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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for KLF12

Z-value: 1.13

Motif logo

Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
ENSG00000118922.18 Kruppel like factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg38_v1_chr13_-_74133892_74133941-0.059.1e-01Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_153778178 1.01 ENST00000532853.5
solute carrier family 27 member 3
chr1_+_109249530 0.78 ENST00000271332.4
cadherin EGF LAG seven-pass G-type receptor 2
chr12_-_54384687 0.60 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
zinc finger protein 385A
chr15_+_40239042 0.47 ENST00000558055.5
ENST00000455577.6
p21 (RAC1) activated kinase 6
chr15_+_40239420 0.46 ENST00000560346.5
p21 (RAC1) activated kinase 6
chr20_+_59577463 0.45 ENST00000359926.7
phosphatase and actin regulator 3
chr11_-_125496122 0.44 ENST00000527534.1
ENST00000278919.8
ENST00000366139.3
fasciculation and elongation protein zeta 1
chr19_+_44777860 0.43 ENST00000341505.4
ENST00000647358.2
Cbl proto-oncogene C
chr1_+_203305510 0.43 ENST00000290551.5
BTG anti-proliferation factor 2
chr11_-_72781858 0.43 ENST00000537947.5
StAR related lipid transfer domain containing 10
chr3_-_190120881 0.43 ENST00000319332.10
prolyl 3-hydroxylase 2
chr11_-_120138104 0.41 ENST00000341846.10
tripartite motif containing 29
chr2_+_233195433 0.40 ENST00000417661.1
inositol polyphosphate-5-phosphatase D
chr8_+_122781621 0.38 ENST00000314393.6
zinc fingers and homeoboxes 2
chr11_-_72781833 0.37 ENST00000535054.1
ENST00000545082.5
StAR related lipid transfer domain containing 10
chr3_+_194136138 0.36 ENST00000232424.4
hes family bHLH transcription factor 1
chr1_+_155127866 0.35 ENST00000368406.2
ENST00000368407.8
ephrin A1
chr5_+_167754918 0.33 ENST00000519204.5
teneurin transmembrane protein 2
chr11_+_121590388 0.32 ENST00000527934.1
sortilin related receptor 1
chr8_+_123182635 0.32 ENST00000276699.10
ENST00000522648.5
family with sequence similarity 83 member A
chr12_-_66678934 0.32 ENST00000545666.5
ENST00000398016.7
ENST00000359742.9
ENST00000538211.5
glutamate receptor interacting protein 1
chr5_-_1882902 0.32 ENST00000231357.7
iroquois homeobox 4
chr14_-_21526312 0.31 ENST00000537235.2
spalt like transcription factor 2
chr14_+_64704380 0.30 ENST00000247226.13
ENST00000394691.7
pleckstrin homology and RhoGEF domain containing G3
chr4_-_170026371 0.29 ENST00000361618.4
ENST00000506764.1
microfibril associated protein 3 like
chr11_-_102530738 0.29 ENST00000260227.5
matrix metallopeptidase 7
chr2_+_202634960 0.29 ENST00000392238.3
family with sequence similarity 117 member B
chr4_-_11428868 0.29 ENST00000002596.6
heparan sulfate-glucosamine 3-sulfotransferase 1
chr14_-_21526391 0.28 ENST00000611430.4
spalt like transcription factor 2
chr5_+_53480619 0.28 ENST00000396947.7
ENST00000256759.8
follistatin
chr16_+_69105636 0.28 ENST00000569188.6
hyaluronan synthase 3
chr20_+_46008900 0.27 ENST00000372330.3
matrix metallopeptidase 9
chr8_+_32647080 0.27 ENST00000520502.7
ENST00000523041.2
ENST00000650819.1
neuregulin 1
chr15_+_73926443 0.27 ENST00000261921.8
lysyl oxidase like 1
chr11_-_1757452 0.27 ENST00000427721.3
novel protein
chr17_-_7294592 0.27 ENST00000007699.10
Y-box binding protein 2
chr1_+_23791138 0.26 ENST00000374514.8
ENST00000420982.5
ENST00000374505.6
lysophospholipase 2
chr17_-_49764123 0.26 ENST00000240364.7
ENST00000506156.1
family with sequence similarity 117 member A
chr1_+_92029971 0.25 ENST00000370383.5
epoxide hydrolase 4
chrX_+_68829009 0.25 ENST00000204961.5
ephrin B1
chr12_-_56488153 0.25 ENST00000311966.9
glutaminase 2
chr12_-_56488350 0.24 ENST00000623608.3
ENST00000610413.4
glutaminase 2
chr18_-_55585773 0.24 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr9_-_96302142 0.24 ENST00000648799.1
hydroxysteroid 17-beta dehydrogenase 3
chr14_+_104724221 0.24 ENST00000330877.7
adenylosuccinate synthase 1
chr4_+_95051671 0.24 ENST00000440890.7
bone morphogenetic protein receptor type 1B
chr12_-_7088848 0.24 ENST00000649804.1
complement C1r
chr3_-_49685090 0.23 ENST00000448220.5
macrophage stimulating 1
chr8_-_139703093 0.23 ENST00000650269.1
ENST00000520439.3
potassium two pore domain channel subfamily K member 9
chr11_-_32435360 0.23 ENST00000639563.3
WT1 transcription factor
chr17_-_38674940 0.23 ENST00000621654.2
elongin BC and polycomb repressive complex 2 associated protein
chr2_+_127423265 0.23 ENST00000402125.2
protein C, inactivator of coagulation factors Va and VIIIa
chr1_+_27234612 0.22 ENST00000319394.8
ENST00000361771.7
WD and tetratricopeptide repeats 1
chr12_+_6951271 0.22 ENST00000456013.5
protein tyrosine phosphatase non-receptor type 6
chr8_-_24956604 0.22 ENST00000610854.2
neurofilament light
chr3_-_14540315 0.22 ENST00000621039.5
glutamate receptor interacting protein 2
chr12_+_6951345 0.21 ENST00000318974.14
ENST00000541698.5
ENST00000542462.1
protein tyrosine phosphatase non-receptor type 6
chr3_-_116444983 0.21 ENST00000333617.8
limbic system associated membrane protein
chr10_+_23694707 0.21 ENST00000376462.5
KIAA1217
chr16_-_9943182 0.21 ENST00000535259.6
glutamate ionotropic receptor NMDA type subunit 2A
chr22_+_46620380 0.20 ENST00000406902.6
GRAM domain containing 4
chr17_+_7705193 0.20 ENST00000226091.3
ephrin B3
chr3_-_61251376 0.20 ENST00000476844.5
ENST00000488467.5
ENST00000492590.6
ENST00000468189.5
fragile histidine triad diadenosine triphosphatase
chr14_+_21057822 0.20 ENST00000308227.2
ribonuclease A family member 8
chr6_+_89080739 0.20 ENST00000369472.1
ENST00000336032.4
proline rich nuclear receptor coactivator 1
chr20_-_32483438 0.19 ENST00000359676.9
nucleolar protein 4 like
chr22_-_39244969 0.19 ENST00000331163.11
platelet derived growth factor subunit B
chr13_-_99971739 0.19 ENST00000267294.4
Zic family member 5
chr17_-_5500997 0.19 ENST00000568641.2
novel protein
chr20_-_32483507 0.19 ENST00000326071.8
nucleolar protein 4 like
chr7_-_44325577 0.19 ENST00000395749.7
calcium/calmodulin dependent protein kinase II beta
chrX_-_11665908 0.19 ENST00000337414.9
Rho GTPase activating protein 6
chr2_+_168802563 0.19 ENST00000445023.6
nitric oxide synthase trafficking
chr9_+_35673917 0.18 ENST00000617161.1
ENST00000378357.9
carbonic anhydrase 9
chr19_+_49335396 0.18 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr2_+_168802610 0.18 ENST00000397206.6
ENST00000317647.12
ENST00000397209.6
nitric oxide synthase trafficking
chr11_+_61392360 0.18 ENST00000334888.9
ENST00000398979.7
transmembrane protein 216
chr8_+_74824526 0.18 ENST00000649643.1
ENST00000260113.7
peptidase inhibitor 15
chr9_+_128322540 0.18 ENST00000609948.1
ENST00000608951.5
coenzyme Q4
chr6_-_27146841 0.17 ENST00000356950.2
H2B clustered histone 12
chr6_+_31927683 0.17 ENST00000456570.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr10_-_89643870 0.17 ENST00000322191.10
ENST00000342512.3
pantothenate kinase 1
chr2_-_228181612 0.17 ENST00000344657.5
SPHK1 interactor, AKAP domain containing
chr1_+_160400543 0.17 ENST00000368061.3
VANGL planar cell polarity protein 2
chr17_+_28744034 0.17 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr12_-_6663083 0.17 ENST00000467678.5
ENST00000493873.1
ENST00000412586.6
ENST00000423703.6
ENST00000444704.5
ENST00000341550.9
inhibitor of growth family member 4
chr4_-_5708530 0.16 ENST00000344408.10
EvC ciliary complex subunit 2
chr2_-_219571241 0.16 ENST00000373876.5
ENST00000603926.5
ENST00000373873.8
ENST00000289656.3
obscurin like cytoskeletal adaptor 1
chr12_+_7061206 0.16 ENST00000423384.5
ENST00000413211.5
complement C1s
chr19_-_45768627 0.16 ENST00000560160.1
SIX homeobox 5
chr12_+_7060676 0.16 ENST00000617865.4
ENST00000402681.7
ENST00000360817.10
complement C1s
chr14_+_41606865 0.16 ENST00000298119.9
leucine rich repeat and fibronectin type III domain containing 5
chr14_+_76376113 0.15 ENST00000644823.1
estrogen related receptor beta
chr2_-_228181669 0.15 ENST00000392056.8
SPHK1 interactor, AKAP domain containing
chr1_+_23791203 0.15 ENST00000374503.7
ENST00000374502.7
lysophospholipase 2
chr12_+_120302316 0.15 ENST00000536460.1
ENST00000202967.4
sirtuin 4
chr1_-_75932392 0.15 ENST00000284142.7
ankyrin repeat and SOCS box containing 17
chr1_-_202808406 0.15 ENST00000650569.1
ENST00000367265.9
ENST00000649770.1
lysine demethylase 5B
chr20_-_40689228 0.15 ENST00000373313.3
MAF bZIP transcription factor B
chr2_+_237966955 0.15 ENST00000414443.5
ENST00000448502.5
ENST00000416292.5
ENST00000409633.5
ENST00000272930.9
ENST00000409953.5
ENST00000409332.5
ubiquitin conjugating enzyme E2 F (putative)
chr17_-_82840010 0.15 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr11_-_16356538 0.15 ENST00000683767.1
SRY-box transcription factor 6
chr1_-_202808464 0.15 ENST00000648469.1
ENST00000648338.1
ENST00000367264.7
ENST00000648473.1
ENST00000648056.1
ENST00000650368.1
lysine demethylase 5B
chr17_+_1762052 0.14 ENST00000254722.9
ENST00000576406.5
ENST00000571149.5
serpin family F member 1
chr2_+_24049673 0.14 ENST00000380991.8
FKBP prolyl isomerase 1B
chr1_+_6785437 0.14 ENST00000303635.12
ENST00000473578.5
ENST00000557126.5
calmodulin binding transcription activator 1
chr15_+_31326807 0.14 ENST00000307145.4
Kruppel like factor 13
chr12_-_10674013 0.14 ENST00000535345.5
ENST00000542562.5
ENST00000075503.8
serine/threonine/tyrosine kinase 1
chr1_+_43991588 0.14 ENST00000372318.8
coiled-coil domain containing 24
chr14_+_103715724 0.14 ENST00000216602.10
zinc finger FYVE-type containing 21
chr2_-_49974182 0.14 ENST00000412315.5
ENST00000378262.7
neurexin 1
chr4_-_20984011 0.13 ENST00000382149.9
potassium voltage-gated channel interacting protein 4
chr14_+_103715767 0.13 ENST00000311141.7
zinc finger FYVE-type containing 21
chr17_-_43022350 0.13 ENST00000587173.5
ENST00000355653.8
vesicle amine transport 1
chr6_-_107115493 0.13 ENST00000369042.6
BEN domain containing 3
chr2_-_49973939 0.13 ENST00000630656.1
neurexin 1
chr2_-_74553049 0.13 ENST00000409549.5
lysyl oxidase like 3
chr19_-_4338786 0.13 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
signal transducing adaptor family member 2
chr11_-_124320197 0.13 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr1_+_50108856 0.13 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr2_+_24049705 0.12 ENST00000380986.9
ENST00000452109.1
FKBP prolyl isomerase 1B
chr14_+_73950489 0.12 ENST00000554320.1
coenzyme Q6, monooxygenase
chr1_+_15756659 0.12 ENST00000375771.5
filamin binding LIM protein 1
chr8_+_32646838 0.12 ENST00000651333.1
ENST00000652592.1
neuregulin 1
chr2_+_184598520 0.12 ENST00000302277.7
zinc finger protein 804A
chr18_+_32018817 0.12 ENST00000217740.4
ENST00000583184.1
ring finger protein 125
novel transcript
chr1_+_6785518 0.12 ENST00000467404.6
calmodulin binding transcription activator 1
chr9_-_111794926 0.12 ENST00000682961.1
ENST00000374283.5
shortage in chiasmata 1
chr11_-_34511710 0.12 ENST00000620316.4
ENST00000312319.6
E74 like ETS transcription factor 5
chr18_-_34224871 0.12 ENST00000261592.10
nucleolar protein 4
chr4_+_102501298 0.12 ENST00000394820.8
ENST00000226574.9
ENST00000511926.5
ENST00000507079.5
nuclear factor kappa B subunit 1
chr18_+_22169580 0.12 ENST00000269216.10
GATA binding protein 6
chr11_+_66593171 0.12 ENST00000533244.6
copper chaperone for superoxide dismutase
chr12_+_6946468 0.12 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr10_-_73641450 0.11 ENST00000359322.5
myozenin 1
chr2_-_74552616 0.11 ENST00000409249.5
lysyl oxidase like 3
chr20_+_35699442 0.11 ENST00000374072.5
ENST00000397416.1
ENST00000336695.4
reactive oxygen species modulator 1
chr1_-_155207886 0.11 ENST00000368378.7
ENST00000541990.5
ENST00000457183.6
ENST00000541576.5
thrombospondin 3
chr11_+_66593194 0.11 ENST00000310190.8
copper chaperone for superoxide dismutase
chr16_-_31073712 0.11 ENST00000414399.1
zinc finger protein 668
chrX_-_112840815 0.11 ENST00000304758.5
ENST00000371959.9
angiomotin
chrX_-_85379659 0.11 ENST00000262753.9
POF1B actin binding protein
chr19_+_43612083 0.11 ENST00000417606.3
serine/arginine repetitive matrix 5
chr11_+_117199363 0.11 ENST00000392951.9
ENST00000525531.5
ENST00000278968.10
transgelin
chr17_+_28744002 0.11 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TNF receptor associated factor 4
chr1_+_32274111 0.11 ENST00000619559.4
ENST00000461712.6
ENST00000373562.7
ENST00000477031.6
ENST00000373557.6
ENST00000333070.4
LCK proto-oncogene, Src family tyrosine kinase
chr3_-_133895867 0.11 ENST00000285208.9
RAB6B, member RAS oncogene family
chr10_+_102644462 0.11 ENST00000643721.2
ENST00000302424.12
tripartite motif containing 8
chr17_-_39401593 0.11 ENST00000394294.7
ENST00000264658.11
ENST00000583610.5
ENST00000647139.1
F-box and leucine rich repeat protein 20
chrX_-_71068384 0.11 ENST00000276105.3
ENST00000622259.4
sorting nexin 12
chr17_-_42112674 0.11 ENST00000251642.8
ENST00000591220.5
DExH-box helicase 58
chr16_+_28878480 0.11 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr11_-_44950151 0.10 ENST00000533940.5
ENST00000533937.1
tumor protein p53 inducible protein 11
chr9_+_113444725 0.10 ENST00000374140.6
regulator of G protein signaling 3
chr12_-_56934403 0.10 ENST00000293502.2
short chain dehydrogenase/reductase family 9C member 7
chr19_-_45496998 0.10 ENST00000245923.9
ENST00000590526.5
ENST00000344680.8
reticulon 2
chr12_-_80937918 0.10 ENST00000552864.6
lin-7 homolog A, crumbs cell polarity complex component
chr20_+_35699227 0.10 ENST00000374078.5
reactive oxygen species modulator 1
chr2_-_49974155 0.10 ENST00000635519.1
neurexin 1
chr2_-_219543793 0.10 ENST00000243776.11
chondroitin polymerizing factor
chr9_+_136977496 0.10 ENST00000371625.8
ENST00000457950.5
prostaglandin D2 synthase
chr20_+_35699368 0.10 ENST00000374077.8
reactive oxygen species modulator 1
chr19_+_35269065 0.10 ENST00000595068.5
ENST00000379134.7
ENST00000594064.5
ENST00000598058.1
upstream transcription factor 2, c-fos interacting
chr17_+_53822887 0.10 ENST00000268919.6
kinesin family member 2B
chr3_-_133895577 0.09 ENST00000543906.5
RAB6B, member RAS oncogene family
chr7_-_79453544 0.09 ENST00000419488.5
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_-_40874216 0.09 ENST00000220507.5
ras homolog family member V
chr19_-_45769204 0.09 ENST00000317578.7
SIX homeobox 5
chr1_-_223364059 0.09 ENST00000343846.7
ENST00000484758.6
ENST00000344029.6
ENST00000366878.9
ENST00000494793.6
ENST00000681285.1
ENST00000680429.1
ENST00000681669.1
ENST00000681305.1
sushi domain containing 4
chr1_+_1308714 0.09 ENST00000467712.1
pseudouridine synthase like 1
chr9_-_114806031 0.09 ENST00000374045.5
TNF superfamily member 15
chr10_-_114174183 0.09 ENST00000369285.7
ENST00000369287.8
ENST00000369286.1
ENST00000648613.1
coiled-coil domain containing 186
chr11_+_36594369 0.09 ENST00000678060.1
ENST00000446510.6
ENST00000676979.1
ENST00000677808.1
ENST00000617650.5
ENST00000334307.10
ENST00000531554.6
ENST00000679022.1
ENST00000347206.8
ENST00000534635.5
ENST00000676921.1
ENST00000678950.1
ENST00000530697.6
ENST00000527108.6
ENST00000532470.3
intraflagellar transport associated protein
chr19_+_45497246 0.09 ENST00000396737.6
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr19_+_45497221 0.09 ENST00000456399.6
protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr19_+_35268921 0.09 ENST00000222305.8
ENST00000343550.9
upstream transcription factor 2, c-fos interacting
chr6_+_135181361 0.09 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chr1_-_115841116 0.09 ENST00000320238.3
nescient helix-loop-helix 2
chr4_+_3441960 0.09 ENST00000382774.8
ENST00000511533.1
HGF activator
chrX_-_84188148 0.09 ENST00000262752.5
ribosomal protein S6 kinase A6
chr14_+_63204436 0.09 ENST00000316754.8
ras homolog family member J
chr4_-_46124046 0.09 ENST00000295452.5
gamma-aminobutyric acid type A receptor subunit gamma1
chr16_+_28878382 0.08 ENST00000357084.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr1_-_201112420 0.08 ENST00000362061.4
ENST00000681874.1
calcium voltage-gated channel subunit alpha1 S
chr19_-_47232649 0.08 ENST00000449228.5
ENST00000300880.11
ENST00000341983.8
BCL2 binding component 3
chr1_-_201112451 0.08 ENST00000367338.7
calcium voltage-gated channel subunit alpha1 S
chr1_+_6034980 0.08 ENST00000378092.6
ENST00000472700.7
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr7_-_79453459 0.08 ENST00000522391.3
ENST00000637441.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_-_55411817 0.08 ENST00000247178.6
autophagy related 14
chr11_-_22625804 0.08 ENST00000327470.6
FA complementation group F
chr11_+_71833200 0.08 ENST00000328698.2
defensin beta 108B
chr22_+_19131271 0.08 ENST00000399635.4
testis specific serine kinase 2
chr18_+_58864866 0.08 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
zinc finger protein 532
chr7_-_79453641 0.08 ENST00000354212.9
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_61361834 0.08 ENST00000544118.5
ENST00000294072.9
ENST00000545361.5
ENST00000539128.5
ENST00000546151.5
ENST00000447532.6
cytochrome b561 family member A3
chr4_+_127781815 0.08 ENST00000508776.5
heat shock protein family A (Hsp70) member 4 like
chr5_-_140043069 0.08 ENST00000289409.8
ENST00000358522.7
ENST00000289422.11
ENST00000541337.5
ENST00000361474.6
neuregulin 2
chr3_-_133895453 0.08 ENST00000486858.5
ENST00000477759.5
RAB6B, member RAS oncogene family
chr14_+_23095491 0.08 ENST00000319074.6
ENST00000554203.1
chromosome 14 open reading frame 119
chr6_+_27147094 0.08 ENST00000377459.3
H2A clustered histone 12

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:0045608 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.3 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.1 0.4 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.6 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.3 GO:0009386 translational attenuation(GO:0009386)
0.1 0.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.8 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.2 GO:1903937 response to acrylamide(GO:1903937)
0.1 0.4 GO:0035787 cell migration involved in kidney development(GO:0035787)
0.1 0.2 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.1 0.2 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.8 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.2 GO:0071931 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.1 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.2 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.0 0.4 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.1 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.0 0.2 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.4 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.3 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.3 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.2 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.2 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0 0.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.4 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.3 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.3 GO:0051715 cytolysis in other organism(GO:0051715)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.0 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.5 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 1.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130) neuroligin family protein binding(GO:0097109)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID EPO PATHWAY EPO signaling pathway
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism