ISMARA results: KLF12

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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for KLF12

Z-value: 1.13

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Transcription factors associated with KLF12

Gene Symbol	Gene ID	Gene Info
KLF12 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000118922.18	Kruppel like factor 12

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
KLF12	hg38_v1_chr13_-_74133892_74133941	-0.05	9.1e-01	Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_+_153778178 Show fit	1.01	ENST00000532853.5	SLC27A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 27 member 3
chr1_+_109249530 Show fit	0.78	ENST00000271332.4	CELSR2 Ensembl NCBI GeneCards UniProt NextProt Show fit	cadherin EGF LAG seven-pass G-type receptor 2
chr12_-_54384687 Show fit	0.60	ENST00000550120.1 ENST00000547210.5 ENST00000394313.7	ZNF385A Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 385A
chr15_+_40239042 Show fit	0.47	ENST00000558055.5 ENST00000455577.6	PAK6 Ensembl NCBI GeneCards UniProt NextProt Show fit	p21 (RAC1) activated kinase 6
chr15_+_40239420 Show fit	0.46	ENST00000560346.5	PAK6 Ensembl NCBI GeneCards UniProt NextProt Show fit	p21 (RAC1) activated kinase 6
chr20_+_59577463 Show fit	0.45	ENST00000359926.7	PHACTR3 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatase and actin regulator 3
chr11_-_125496122 Show fit	0.44	ENST00000527534.1 ENST00000278919.8 ENST00000366139.3	FEZ1 Ensembl NCBI GeneCards UniProt NextProt Show fit	fasciculation and elongation protein zeta 1
chr19_+_44777860 Show fit	0.43	ENST00000341505.4 ENST00000647358.2	CBLC Ensembl NCBI GeneCards UniProt NextProt Show fit	Cbl proto-oncogene C
chr1_+_203305510 Show fit	0.43	ENST00000290551.5	BTG2 Ensembl NCBI GeneCards UniProt NextProt Show fit	BTG anti-proliferation factor 2
chr11_-_72781858 Show fit	0.43	ENST00000537947.5	STARD10 Ensembl NCBI GeneCards UniProt NextProt Show fit	StAR related lipid transfer domain containing 10
chr3_-_190120881 Show fit	0.43	ENST00000319332.10	P3H2 Ensembl NCBI GeneCards UniProt NextProt Show fit	prolyl 3-hydroxylase 2
chr11_-_120138104 Show fit	0.41	ENST00000341846.10	TRIM29 Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 29
chr2_+_233195433 Show fit	0.40	ENST00000417661.1	INPP5D Ensembl NCBI GeneCards UniProt NextProt Show fit	inositol polyphosphate-5-phosphatase D
chr8_+_122781621 Show fit	0.38	ENST00000314393.6	ZHX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc fingers and homeoboxes 2
chr11_-_72781833 Show fit	0.37	ENST00000535054.1 ENST00000545082.5	STARD10 Ensembl NCBI GeneCards UniProt NextProt Show fit	StAR related lipid transfer domain containing 10
chr3_+_194136138 Show fit	0.36	ENST00000232424.4	HES1 Ensembl NCBI GeneCards UniProt NextProt Show fit	hes family bHLH transcription factor 1
chr1_+_155127866 Show fit	0.35	ENST00000368406.2 ENST00000368407.8	EFNA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ephrin A1
chr5_+_167754918 Show fit	0.33	ENST00000519204.5	TENM2 Ensembl NCBI GeneCards UniProt NextProt Show fit	teneurin transmembrane protein 2
chr11_+_121590388 Show fit	0.32	ENST00000527934.1	SORL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	sortilin related receptor 1
chr8_+_123182635 Show fit	0.32	ENST00000276699.10 ENST00000522648.5	FAM83A Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 83 member A
chr12_-_66678934 Show fit	0.32	ENST00000545666.5 ENST00000398016.7 ENST00000359742.9 ENST00000538211.5	GRIP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor interacting protein 1
chr5_-_1882902 Show fit	0.32	ENST00000231357.7	IRX4 Ensembl NCBI GeneCards UniProt NextProt Show fit	iroquois homeobox 4
chr14_-_21526312 Show fit	0.31	ENST00000537235.2	SALL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	spalt like transcription factor 2
chr14_+_64704380 Show fit	0.30	ENST00000247226.13 ENST00000394691.7	PLEKHG3 Ensembl NCBI GeneCards UniProt NextProt Show fit	pleckstrin homology and RhoGEF domain containing G3
chr4_-_170026371 Show fit	0.29	ENST00000361618.4 ENST00000506764.1	MFAP3L Ensembl NCBI GeneCards UniProt NextProt Show fit	microfibril associated protein 3 like
chr11_-_102530738 Show fit	0.29	ENST00000260227.5	MMP7 Ensembl NCBI GeneCards UniProt NextProt Show fit	matrix metallopeptidase 7
chr2_+_202634960 Show fit	0.29	ENST00000392238.3	FAM117B Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 117 member B
chr4_-_11428868 Show fit	0.29	ENST00000002596.6	HS3ST1 Ensembl NCBI GeneCards UniProt NextProt Show fit	heparan sulfate-glucosamine 3-sulfotransferase 1
chr14_-_21526391 Show fit	0.28	ENST00000611430.4	SALL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	spalt like transcription factor 2
chr5_+_53480619 Show fit	0.28	ENST00000396947.7 ENST00000256759.8	FST Ensembl NCBI GeneCards UniProt NextProt Show fit	follistatin
chr16_+_69105636 Show fit	0.28	ENST00000569188.6	HAS3 Ensembl NCBI GeneCards UniProt NextProt Show fit	hyaluronan synthase 3
chr20_+_46008900 Show fit	0.27	ENST00000372330.3	MMP9 Ensembl NCBI GeneCards UniProt NextProt Show fit	matrix metallopeptidase 9
chr8_+_32647080 Show fit	0.27	ENST00000520502.7 ENST00000523041.2 ENST00000650819.1	NRG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neuregulin 1
chr15_+_73926443 Show fit	0.27	ENST00000261921.8	LOXL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	lysyl oxidase like 1
chr11_-_1757452 Show fit	0.27	ENST00000427721.3	ENSG00000250644.3 Ensembl NCBI GeneCards UniProt NextProt Show fit	novel protein
chr17_-_7294592 Show fit	0.27	ENST00000007699.10	YBX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	Y-box binding protein 2
chr1_+_23791138 Show fit	0.26	ENST00000374514.8 ENST00000420982.5 ENST00000374505.6	LYPLA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	lysophospholipase 2
chr17_-_49764123 Show fit	0.26	ENST00000240364.7 ENST00000506156.1	FAM117A Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 117 member A
chr1_+_92029971 Show fit	0.25	ENST00000370383.5	EPHX4 Ensembl NCBI GeneCards UniProt NextProt Show fit	epoxide hydrolase 4
chrX_+_68829009 Show fit	0.25	ENST00000204961.5	EFNB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ephrin B1
chr12_-_56488153 Show fit	0.25	ENST00000311966.9	GLS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	glutaminase 2
chr12_-_56488350 Show fit	0.24	ENST00000623608.3 ENST00000610413.4	GLS2 Ensembl NCBI GeneCards UniProt NextProt Show fit	glutaminase 2
chr18_-_55585773 Show fit	0.24	ENST00000563824.5 ENST00000626425.2 ENST00000566514.5 ENST00000568673.5 ENST00000562847.5 ENST00000568147.5	TCF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor 4
chr9_-_96302142 Show fit	0.24	ENST00000648799.1	HSD17B3 Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxysteroid 17-beta dehydrogenase 3
chr14_+_104724221 Show fit	0.24	ENST00000330877.7	ADSS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	adenylosuccinate synthase 1
chr4_+_95051671 Show fit	0.24	ENST00000440890.7	BMPR1B Ensembl NCBI GeneCards UniProt NextProt Show fit	bone morphogenetic protein receptor type 1B
chr12_-_7088848 Show fit	0.24	ENST00000649804.1	C1R Ensembl NCBI GeneCards UniProt NextProt Show fit	complement C1r
chr3_-_49685090 Show fit	0.23	ENST00000448220.5	MST1 Ensembl NCBI GeneCards UniProt NextProt Show fit	macrophage stimulating 1
chr8_-_139703093 Show fit	0.23	ENST00000650269.1 ENST00000520439.3	KCNK9 Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium two pore domain channel subfamily K member 9
chr11_-_32435360 Show fit	0.23	ENST00000639563.3	WT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	WT1 transcription factor
chr17_-_38674940 Show fit	0.23	ENST00000621654.2	EPOP Ensembl NCBI GeneCards UniProt NextProt Show fit	elongin BC and polycomb repressive complex 2 associated protein
chr2_+_127423265 Show fit	0.23	ENST00000402125.2	PROC Ensembl NCBI GeneCards UniProt NextProt Show fit	protein C, inactivator of coagulation factors Va and VIIIa
chr1_+_27234612 Show fit	0.22	ENST00000319394.8 ENST00000361771.7	WDTC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	WD and tetratricopeptide repeats 1
chr12_+_6951271 Show fit	0.22	ENST00000456013.5	PTPN6 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr8_-_24956604 Show fit	0.22	ENST00000610854.2	NEFL Ensembl NCBI GeneCards UniProt NextProt Show fit	neurofilament light
chr3_-_14540315 Show fit	0.22	ENST00000621039.5	GRIP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate receptor interacting protein 2
chr12_+_6951345 Show fit	0.21	ENST00000318974.14 ENST00000541698.5 ENST00000542462.1	PTPN6 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr3_-_116444983 Show fit	0.21	ENST00000333617.8	LSAMP Ensembl NCBI GeneCards UniProt NextProt Show fit	limbic system associated membrane protein
chr10_+_23694707 Show fit	0.21	ENST00000376462.5	KIAA1217 Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA1217
chr16_-_9943182 Show fit	0.21	ENST00000535259.6	GRIN2A Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamate ionotropic receptor NMDA type subunit 2A
chr22_+_46620380 Show fit	0.20	ENST00000406902.6	GRAMD4 Ensembl NCBI GeneCards UniProt NextProt Show fit	GRAM domain containing 4
chr17_+_7705193 Show fit	0.20	ENST00000226091.3	EFNB3 Ensembl NCBI GeneCards UniProt NextProt Show fit	ephrin B3
chr3_-_61251376 Show fit	0.20	ENST00000476844.5 ENST00000488467.5 ENST00000492590.6 ENST00000468189.5	FHIT Ensembl NCBI GeneCards UniProt NextProt Show fit	fragile histidine triad diadenosine triphosphatase
chr14_+_21057822 Show fit	0.20	ENST00000308227.2	RNASE8 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribonuclease A family member 8
chr6_+_89080739 Show fit	0.20	ENST00000369472.1 ENST00000336032.4	PNRC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	proline rich nuclear receptor coactivator 1
chr20_-_32483438 Show fit	0.19	ENST00000359676.9	NOL4L Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleolar protein 4 like
chr22_-_39244969 Show fit	0.19	ENST00000331163.11	PDGFB Ensembl NCBI GeneCards UniProt NextProt Show fit	platelet derived growth factor subunit B
chr13_-_99971739 Show fit	0.19	ENST00000267294.4	ZIC5 Ensembl NCBI GeneCards UniProt NextProt Show fit	Zic family member 5
chr17_-_5500997 Show fit	0.19	ENST00000568641.2	ENSG00000286190.2 Ensembl NCBI GeneCards UniProt NextProt Show fit	novel protein
chr20_-_32483507 Show fit	0.19	ENST00000326071.8	NOL4L Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleolar protein 4 like
chr7_-_44325577 Show fit	0.19	ENST00000395749.7	CAMK2B Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium/calmodulin dependent protein kinase II beta
chrX_-_11665908 Show fit	0.19	ENST00000337414.9	ARHGAP6 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho GTPase activating protein 6
chr2_+_168802563 Show fit	0.19	ENST00000445023.6	NOSTRIN Ensembl NCBI GeneCards UniProt NextProt Show fit	nitric oxide synthase trafficking
chr9_+_35673917 Show fit	0.18	ENST00000617161.1 ENST00000378357.9	CA9 Ensembl NCBI GeneCards UniProt NextProt Show fit	carbonic anhydrase 9
chr19_+_49335396 Show fit	0.18	ENST00000598095.5 ENST00000426897.6 ENST00000323906.9 ENST00000535669.6 ENST00000597602.1 ENST00000595660.1	CD37 Ensembl NCBI GeneCards UniProt NextProt Show fit	CD37 molecule
chr2_+_168802610 Show fit	0.18	ENST00000397206.6 ENST00000317647.12 ENST00000397209.6	NOSTRIN Ensembl NCBI GeneCards UniProt NextProt Show fit	nitric oxide synthase trafficking
chr11_+_61392360 Show fit	0.18	ENST00000334888.9 ENST00000398979.7	TMEM216 Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 216
chr8_+_74824526 Show fit	0.18	ENST00000649643.1 ENST00000260113.7	PI15 Ensembl NCBI GeneCards UniProt NextProt Show fit	peptidase inhibitor 15
chr9_+_128322540 Show fit	0.18	ENST00000609948.1 ENST00000608951.5	COQ4 Ensembl NCBI GeneCards UniProt NextProt Show fit	coenzyme Q4
chr6_-_27146841 Show fit	0.17	ENST00000356950.2	H2BC12 Ensembl NCBI GeneCards UniProt NextProt Show fit	H2B clustered histone 12
chr6_+_31927683 Show fit	0.17	ENST00000456570.5	ENSG00000244255.5 Ensembl NCBI GeneCards UniProt NextProt Show fit	novel complement component 2 (C2) and complement factor B (CFB) protein
chr10_-_89643870 Show fit	0.17	ENST00000322191.10 ENST00000342512.3	PANK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	pantothenate kinase 1
chr2_-_228181612 Show fit	0.17	ENST00000344657.5	SPHKAP Ensembl NCBI GeneCards UniProt NextProt Show fit	SPHK1 interactor, AKAP domain containing
chr1_+_160400543 Show fit	0.17	ENST00000368061.3	VANGL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	VANGL planar cell polarity protein 2
chr17_+_28744034 Show fit	0.17	ENST00000444415.7 ENST00000262396.10	TRAF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	TNF receptor associated factor 4
chr12_-_6663083 Show fit	0.17	ENST00000467678.5 ENST00000493873.1 ENST00000412586.6 ENST00000423703.6 ENST00000444704.5 ENST00000341550.9	ING4 Ensembl NCBI GeneCards UniProt NextProt Show fit	inhibitor of growth family member 4
chr4_-_5708530 Show fit	0.16	ENST00000344408.10	EVC2 Ensembl NCBI GeneCards UniProt NextProt Show fit	EvC ciliary complex subunit 2
chr2_-_219571241 Show fit	0.16	ENST00000373876.5 ENST00000603926.5 ENST00000373873.8 ENST00000289656.3	OBSL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	obscurin like cytoskeletal adaptor 1
chr12_+_7061206 Show fit	0.16	ENST00000423384.5 ENST00000413211.5	C1S Ensembl NCBI GeneCards UniProt NextProt Show fit	complement C1s
chr19_-_45768627 Show fit	0.16	ENST00000560160.1	SIX5 Ensembl NCBI GeneCards UniProt NextProt Show fit	SIX homeobox 5
chr12_+_7060676 Show fit	0.16	ENST00000617865.4 ENST00000402681.7 ENST00000360817.10	C1S Ensembl NCBI GeneCards UniProt NextProt Show fit	complement C1s
chr14_+_41606865 Show fit	0.16	ENST00000298119.9	LRFN5 Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat and fibronectin type III domain containing 5
chr14_+_76376113 Show fit	0.15	ENST00000644823.1	ESRRB Ensembl NCBI GeneCards UniProt NextProt Show fit	estrogen related receptor beta
chr2_-_228181669 Show fit	0.15	ENST00000392056.8	SPHKAP Ensembl NCBI GeneCards UniProt NextProt Show fit	SPHK1 interactor, AKAP domain containing
chr1_+_23791203 Show fit	0.15	ENST00000374503.7 ENST00000374502.7	LYPLA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	lysophospholipase 2
chr12_+_120302316 Show fit	0.15	ENST00000536460.1 ENST00000202967.4	SIRT4 Ensembl NCBI GeneCards UniProt NextProt Show fit	sirtuin 4
chr1_-_75932392 Show fit	0.15	ENST00000284142.7	ASB17 Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat and SOCS box containing 17
chr1_-_202808406 Show fit	0.15	ENST00000650569.1 ENST00000367265.9 ENST00000649770.1	KDM5B Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine demethylase 5B
chr20_-_40689228 Show fit	0.15	ENST00000373313.3	MAFB Ensembl NCBI GeneCards UniProt NextProt Show fit	MAF bZIP transcription factor B
chr2_+_237966955 Show fit	0.15	ENST00000414443.5 ENST00000448502.5 ENST00000416292.5 ENST00000409633.5 ENST00000272930.9 ENST00000409953.5 ENST00000409332.5	UBE2F Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin conjugating enzyme E2 F (putative)
chr17_-_82840010 Show fit	0.15	ENST00000269394.4 ENST00000572562.1	ZNF750 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 750
chr11_-_16356538 Show fit	0.15	ENST00000683767.1	SOX6 Ensembl NCBI GeneCards UniProt NextProt Show fit	SRY-box transcription factor 6
chr1_-_202808464 Show fit	0.15	ENST00000648469.1 ENST00000648338.1 ENST00000367264.7 ENST00000648473.1 ENST00000648056.1 ENST00000650368.1	KDM5B Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine demethylase 5B
chr17_+_1762052 Show fit	0.14	ENST00000254722.9 ENST00000576406.5 ENST00000571149.5	SERPINF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin family F member 1
chr2_+_24049673 Show fit	0.14	ENST00000380991.8	FKBP1B Ensembl NCBI GeneCards UniProt NextProt Show fit	FKBP prolyl isomerase 1B
chr1_+_6785437 Show fit	0.14	ENST00000303635.12 ENST00000473578.5 ENST00000557126.5	CAMTA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	calmodulin binding transcription activator 1
chr15_+_31326807 Show fit	0.14	ENST00000307145.4	KLF13 Ensembl NCBI GeneCards UniProt NextProt Show fit	Kruppel like factor 13
chr12_-_10674013 Show fit	0.14	ENST00000535345.5 ENST00000542562.5 ENST00000075503.8	STYK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/threonine/tyrosine kinase 1
chr1_+_43991588 Show fit	0.14	ENST00000372318.8	CCDC24 Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 24
chr14_+_103715724 Show fit	0.14	ENST00000216602.10	ZFYVE21 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger FYVE-type containing 21
chr2_-_49974182 Show fit	0.14	ENST00000412315.5 ENST00000378262.7	NRXN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 1
chr4_-_20984011 Show fit	0.13	ENST00000382149.9	KCNIP4 Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium voltage-gated channel interacting protein 4
chr14_+_103715767 Show fit	0.13	ENST00000311141.7	ZFYVE21 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger FYVE-type containing 21
chr17_-_43022350 Show fit	0.13	ENST00000587173.5 ENST00000355653.8	VAT1 Ensembl NCBI GeneCards UniProt NextProt Show fit	vesicle amine transport 1
chr6_-_107115493 Show fit	0.13	ENST00000369042.6	BEND3 Ensembl NCBI GeneCards UniProt NextProt Show fit	BEN domain containing 3
chr2_-_49973939 Show fit	0.13	ENST00000630656.1	NRXN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 1
chr2_-_74553049 Show fit	0.13	ENST00000409549.5	LOXL3 Ensembl NCBI GeneCards UniProt NextProt Show fit	lysyl oxidase like 3
chr19_-_4338786 Show fit	0.13	ENST00000601482.1 ENST00000600324.5 ENST00000594605.6	STAP2 Ensembl NCBI GeneCards UniProt NextProt Show fit	signal transducing adaptor family member 2
chr11_-_124320197 Show fit	0.13	ENST00000624618.2	OR8D2 Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactory receptor family 8 subfamily D member 2
chr1_+_50108856 Show fit	0.13	ENST00000650764.1 ENST00000494555.2 ENST00000371824.7 ENST00000371823.8 ENST00000652693.1	ELAVL4 Ensembl NCBI GeneCards UniProt NextProt Show fit	ELAV like RNA binding protein 4
chr2_+_24049705 Show fit	0.12	ENST00000380986.9 ENST00000452109.1	FKBP1B Ensembl NCBI GeneCards UniProt NextProt Show fit	FKBP prolyl isomerase 1B
chr14_+_73950489 Show fit	0.12	ENST00000554320.1	COQ6 Ensembl NCBI GeneCards UniProt NextProt Show fit	coenzyme Q6, monooxygenase
chr1_+_15756659 Show fit	0.12	ENST00000375771.5	FBLIM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	filamin binding LIM protein 1
chr8_+_32646838 Show fit	0.12	ENST00000651333.1 ENST00000652592.1	NRG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neuregulin 1
chr2_+_184598520 Show fit	0.12	ENST00000302277.7	ZNF804A Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 804A
chr18_+_32018817 Show fit	0.12	ENST00000217740.4 ENST00000583184.1	RNF125 Ensembl NCBI GeneCards UniProt NextProt Show fit ENSG00000263917.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 125 novel transcript
chr1_+_6785518 Show fit	0.12	ENST00000467404.6	CAMTA1 Ensembl NCBI GeneCards UniProt NextProt Show fit	calmodulin binding transcription activator 1
chr9_-_111794926 Show fit	0.12	ENST00000682961.1 ENST00000374283.5	SHOC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	shortage in chiasmata 1
chr11_-_34511710 Show fit	0.12	ENST00000620316.4 ENST00000312319.6	ELF5 Ensembl NCBI GeneCards UniProt NextProt Show fit	E74 like ETS transcription factor 5
chr18_-_34224871 Show fit	0.12	ENST00000261592.10	NOL4 Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleolar protein 4
chr4_+_102501298 Show fit	0.12	ENST00000394820.8 ENST00000226574.9 ENST00000511926.5 ENST00000507079.5	NFKB1 Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor kappa B subunit 1
chr18_+_22169580 Show fit	0.12	ENST00000269216.10	GATA6 Ensembl NCBI GeneCards UniProt NextProt Show fit	GATA binding protein 6
chr11_+_66593171 Show fit	0.12	ENST00000533244.6	CCS Ensembl NCBI GeneCards UniProt NextProt Show fit	copper chaperone for superoxide dismutase
chr12_+_6946468 Show fit	0.12	ENST00000543115.5 ENST00000399448.5	PTPN6 Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine phosphatase non-receptor type 6
chr10_-_73641450 Show fit	0.11	ENST00000359322.5	MYOZ1 Ensembl NCBI GeneCards UniProt NextProt Show fit	myozenin 1
chr2_-_74552616 Show fit	0.11	ENST00000409249.5	LOXL3 Ensembl NCBI GeneCards UniProt NextProt Show fit	lysyl oxidase like 3
chr20_+_35699442 Show fit	0.11	ENST00000374072.5 ENST00000397416.1 ENST00000336695.4	ROMO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	reactive oxygen species modulator 1
chr1_-_155207886 Show fit	0.11	ENST00000368378.7 ENST00000541990.5 ENST00000457183.6 ENST00000541576.5	THBS3 Ensembl NCBI GeneCards UniProt NextProt Show fit	thrombospondin 3
chr11_+_66593194 Show fit	0.11	ENST00000310190.8	CCS Ensembl NCBI GeneCards UniProt NextProt Show fit	copper chaperone for superoxide dismutase
chr16_-_31073712 Show fit	0.11	ENST00000414399.1	ZNF668 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 668
chrX_-_112840815 Show fit	0.11	ENST00000304758.5 ENST00000371959.9	AMOT Ensembl NCBI GeneCards UniProt NextProt Show fit	angiomotin
chrX_-_85379659 Show fit	0.11	ENST00000262753.9	POF1B Ensembl NCBI GeneCards UniProt NextProt Show fit	POF1B actin binding protein
chr19_+_43612083 Show fit	0.11	ENST00000417606.3	SRRM5 Ensembl NCBI GeneCards UniProt NextProt Show fit	serine/arginine repetitive matrix 5
chr11_+_117199363 Show fit	0.11	ENST00000392951.9 ENST00000525531.5 ENST00000278968.10	TAGLN Ensembl NCBI GeneCards UniProt NextProt Show fit	transgelin
chr17_+_28744002 Show fit	0.11	ENST00000618771.1 ENST00000262395.10 ENST00000422344.5	TRAF4 Ensembl NCBI GeneCards UniProt NextProt Show fit	TNF receptor associated factor 4
chr1_+_32274111 Show fit	0.11	ENST00000619559.4 ENST00000461712.6 ENST00000373562.7 ENST00000477031.6 ENST00000373557.6 ENST00000333070.4	LCK Ensembl NCBI GeneCards UniProt NextProt Show fit	LCK proto-oncogene, Src family tyrosine kinase
chr3_-_133895867 Show fit	0.11	ENST00000285208.9	RAB6B Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB6B, member RAS oncogene family
chr10_+_102644462 Show fit	0.11	ENST00000643721.2 ENST00000302424.12	TRIM8 Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 8
chr17_-_39401593 Show fit	0.11	ENST00000394294.7 ENST00000264658.11 ENST00000583610.5 ENST00000647139.1	FBXL20 Ensembl NCBI GeneCards UniProt NextProt Show fit	F-box and leucine rich repeat protein 20
chrX_-_71068384 Show fit	0.11	ENST00000276105.3 ENST00000622259.4	SNX12 Ensembl NCBI GeneCards UniProt NextProt Show fit	sorting nexin 12
chr17_-_42112674 Show fit	0.11	ENST00000251642.8 ENST00000591220.5	DHX58 Ensembl NCBI GeneCards UniProt NextProt Show fit	DExH-box helicase 58
chr16_+_28878480 Show fit	0.11	ENST00000395503.9	ATP2A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr11_-_44950151 Show fit	0.10	ENST00000533940.5 ENST00000533937.1	TP53I11 Ensembl NCBI GeneCards UniProt NextProt Show fit	tumor protein p53 inducible protein 11
chr9_+_113444725 Show fit	0.10	ENST00000374140.6	RGS3 Ensembl NCBI GeneCards UniProt NextProt Show fit	regulator of G protein signaling 3
chr12_-_56934403 Show fit	0.10	ENST00000293502.2	SDR9C7 Ensembl NCBI GeneCards UniProt NextProt Show fit	short chain dehydrogenase/reductase family 9C member 7
chr19_-_45496998 Show fit	0.10	ENST00000245923.9 ENST00000590526.5 ENST00000344680.8	RTN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	reticulon 2
chr12_-_80937918 Show fit	0.10	ENST00000552864.6	LIN7A Ensembl NCBI GeneCards UniProt NextProt Show fit	lin-7 homolog A, crumbs cell polarity complex component
chr20_+_35699227 Show fit	0.10	ENST00000374078.5	ROMO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	reactive oxygen species modulator 1
chr2_-_49974155 Show fit	0.10	ENST00000635519.1	NRXN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 1
chr2_-_219543793 Show fit	0.10	ENST00000243776.11	CHPF Ensembl NCBI GeneCards UniProt NextProt Show fit	chondroitin polymerizing factor
chr9_+_136977496 Show fit	0.10	ENST00000371625.8 ENST00000457950.5	PTGDS Ensembl NCBI GeneCards UniProt NextProt Show fit	prostaglandin D2 synthase
chr20_+_35699368 Show fit	0.10	ENST00000374077.8	ROMO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	reactive oxygen species modulator 1
chr19_+_35269065 Show fit	0.10	ENST00000595068.5 ENST00000379134.7 ENST00000594064.5 ENST00000598058.1	USF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	upstream transcription factor 2, c-fos interacting
chr17_+_53822887 Show fit	0.10	ENST00000268919.6	KIF2B Ensembl NCBI GeneCards UniProt NextProt Show fit	kinesin family member 2B
chr3_-_133895577 Show fit	0.09	ENST00000543906.5	RAB6B Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB6B, member RAS oncogene family
chr7_-_79453544 Show fit	0.09	ENST00000419488.5	MAGI2 Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_-_40874216 Show fit	0.09	ENST00000220507.5	RHOV Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member V
chr19_-_45769204 Show fit	0.09	ENST00000317578.7	SIX5 Ensembl NCBI GeneCards UniProt NextProt Show fit	SIX homeobox 5
chr1_-_223364059 Show fit	0.09	ENST00000343846.7 ENST00000484758.6 ENST00000344029.6 ENST00000366878.9 ENST00000494793.6 ENST00000681285.1 ENST00000680429.1 ENST00000681669.1 ENST00000681305.1	SUSD4 Ensembl NCBI GeneCards UniProt NextProt Show fit	sushi domain containing 4
chr1_+_1308714 Show fit	0.09	ENST00000467712.1	PUSL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	pseudouridine synthase like 1
chr9_-_114806031 Show fit	0.09	ENST00000374045.5	TNFSF15 Ensembl NCBI GeneCards UniProt NextProt Show fit	TNF superfamily member 15
chr10_-_114174183 Show fit	0.09	ENST00000369285.7 ENST00000369287.8 ENST00000369286.1 ENST00000648613.1	CCDC186 Ensembl NCBI GeneCards UniProt NextProt Show fit	coiled-coil domain containing 186
chr11_+_36594369 Show fit	0.09	ENST00000678060.1 ENST00000446510.6 ENST00000676979.1 ENST00000677808.1 ENST00000617650.5 ENST00000334307.10 ENST00000531554.6 ENST00000679022.1 ENST00000347206.8 ENST00000534635.5 ENST00000676921.1 ENST00000678950.1 ENST00000530697.6 ENST00000527108.6 ENST00000532470.3	IFTAP Ensembl NCBI GeneCards UniProt NextProt Show fit	intraflagellar transport associated protein
chr19_+_45497246 Show fit	0.09	ENST00000396737.6	PPM1N Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr19_+_45497221 Show fit	0.09	ENST00000456399.6	PPM1N Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)
chr19_+_35268921 Show fit	0.09	ENST00000222305.8 ENST00000343550.9	USF2 Ensembl NCBI GeneCards UniProt NextProt Show fit	upstream transcription factor 2, c-fos interacting
chr6_+_135181361 Show fit	0.09	ENST00000527615.5 ENST00000420123.6 ENST00000525369.5 ENST00000528774.5 ENST00000533624.5 ENST00000534044.5 ENST00000534121.5	MYB Ensembl NCBI GeneCards UniProt NextProt Show fit	MYB proto-oncogene, transcription factor
chr1_-_115841116 Show fit	0.09	ENST00000320238.3	NHLH2 Ensembl NCBI GeneCards UniProt NextProt Show fit	nescient helix-loop-helix 2
chr4_+_3441960 Show fit	0.09	ENST00000382774.8 ENST00000511533.1	HGFAC Ensembl NCBI GeneCards UniProt NextProt Show fit	HGF activator
chrX_-_84188148 Show fit	0.09	ENST00000262752.5	RPS6KA6 Ensembl NCBI GeneCards UniProt NextProt Show fit	ribosomal protein S6 kinase A6
chr14_+_63204436 Show fit	0.09	ENST00000316754.8	RHOJ Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member J
chr4_-_46124046 Show fit	0.09	ENST00000295452.5	GABRG1 Ensembl NCBI GeneCards UniProt NextProt Show fit	gamma-aminobutyric acid type A receptor subunit gamma1
chr16_+_28878382 Show fit	0.08	ENST00000357084.7	ATP2A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr1_-_201112420 Show fit	0.08	ENST00000362061.4 ENST00000681874.1	CACNA1S Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium voltage-gated channel subunit alpha1 S
chr19_-_47232649 Show fit	0.08	ENST00000449228.5 ENST00000300880.11 ENST00000341983.8	BBC3 Ensembl NCBI GeneCards UniProt NextProt Show fit	BCL2 binding component 3
chr1_-_201112451 Show fit	0.08	ENST00000367338.7	CACNA1S Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium voltage-gated channel subunit alpha1 S
chr1_+_6034980 Show fit	0.08	ENST00000378092.6 ENST00000472700.7	KCNAB2 Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr7_-_79453459 Show fit	0.08	ENST00000522391.3 ENST00000637441.1	MAGI2 Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_-_55411817 Show fit	0.08	ENST00000247178.6	ATG14 Ensembl NCBI GeneCards UniProt NextProt Show fit	autophagy related 14
chr11_-_22625804 Show fit	0.08	ENST00000327470.6	FANCF Ensembl NCBI GeneCards UniProt NextProt Show fit	FA complementation group F
chr11_+_71833200 Show fit	0.08	ENST00000328698.2	DEFB108B Ensembl NCBI GeneCards UniProt NextProt Show fit	defensin beta 108B
chr22_+_19131271 Show fit	0.08	ENST00000399635.4	TSSK2 Ensembl NCBI GeneCards UniProt NextProt Show fit	testis specific serine kinase 2
chr18_+_58864866 Show fit	0.08	ENST00000588456.5 ENST00000591808.6 ENST00000589481.1 ENST00000591049.1	ZNF532 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 532
chr7_-_79453641 Show fit	0.08	ENST00000354212.9	MAGI2 Ensembl NCBI GeneCards UniProt NextProt Show fit	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_61361834 Show fit	0.08	ENST00000544118.5 ENST00000294072.9 ENST00000545361.5 ENST00000539128.5 ENST00000546151.5 ENST00000447532.6	CYB561A3 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome b561 family member A3
chr4_+_127781815 Show fit	0.08	ENST00000508776.5	HSPA4L Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock protein family A (Hsp70) member 4 like
chr5_-_140043069 Show fit	0.08	ENST00000289409.8 ENST00000358522.7 ENST00000289422.11 ENST00000541337.5 ENST00000361474.6	NRG2 Ensembl NCBI GeneCards UniProt NextProt Show fit	neuregulin 2
chr3_-_133895453 Show fit	0.08	ENST00000486858.5 ENST00000477759.5	RAB6B Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB6B, member RAS oncogene family
chr14_+_23095491 Show fit	0.08	ENST00000319074.6 ENST00000554203.1	C14orf119 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 14 open reading frame 119
chr6_+_27147094 Show fit	0.08	ENST00000377459.3	H2AC12 Ensembl NCBI GeneCards UniProt NextProt Show fit	H2A clustered histone 12

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:1902162	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1	0.4	GO:0045608	trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) negative regulation of pro-B cell differentiation(GO:2000974)
0.1	0.3	GO:1902769	regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1	0.3	GO:0048560	establishment of anatomical structure orientation(GO:0048560)
0.1	0.4	GO:0045659	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1	0.6	GO:0033277	abortive mitotic cell cycle(GO:0033277)
0.1	0.3	GO:0009386	translational attenuation(GO:0009386)
0.1	0.5	GO:0006543	glutamine catabolic process(GO:0006543)
0.1	0.2	GO:0018057	peptidyl-lysine oxidation(GO:0018057)
0.1	0.8	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.1	0.2	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.1	0.2	GO:1903937	response to acrylamide(GO:1903937)
0.1	0.4	GO:0035787	cell migration involved in kidney development(GO:0035787)
0.1	0.2	GO:0090076	regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.1	0.2	GO:0072299	negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1	0.8	GO:0032782	bile acid secretion(GO:0032782)
0.1	0.4	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1	0.2	GO:0045226	extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1	0.2	GO:1990922	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1	0.2	GO:0071931	regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0	0.1	GO:1903217	regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0	0.2	GO:0033058	directional locomotion(GO:0033058)
0.0	0.1	GO:2000642	negative regulation of early endosome to late endosome transport(GO:2000642)
0.0	0.4	GO:0002084	protein depalmitoylation(GO:0002084)
0.0	0.2	GO:0061760	antifungal innate immune response(GO:0061760)
0.0	0.1	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0	0.1	GO:0032912	negative regulation of transforming growth factor beta2 production(GO:0032912)
0.0	0.2	GO:0015680	intracellular copper ion transport(GO:0015680)
0.0	0.1	GO:0035283	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.4	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.1	GO:0021780	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.3	GO:1902723	negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0	0.3	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0	0.2	GO:0034721	histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0	0.3	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0	0.2	GO:1902731	ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0	0.1	GO:0043973	histone H3-K4 acetylation(GO:0043973)
0.0	0.2	GO:0000432	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.0	0.4	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0	0.5	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.4	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0	0.3	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	0.1	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0	0.1	GO:0072272	proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0	0.1	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0	0.1	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0	0.3	GO:0051715	cytolysis in other organism(GO:0051715)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.2	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.2	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0	0.2	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279)
0.0	0.4	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.3	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.4	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.2	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.1	GO:0001712	ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0	0.4	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.1	GO:0016240	autophagosome docking(GO:0016240)
0.0	0.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.3	GO:0097264	self proteolysis(GO:0097264)
0.0	0.3	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.1	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0	0.2	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.3	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.2	GO:0071313	cellular response to caffeine(GO:0071313)
0.0	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.1	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.1	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0070995	NADPH oxidation(GO:0070995)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0036117	hyaluranon cable(GO:0036117)
0.1	0.2	GO:0060187	cell pole(GO:0060187)
0.1	0.2	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.1	0.8	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.6	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.2	GO:0014802	terminal cisterna(GO:0014802)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.1	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.1	GO:0060342	photoreceptor inner segment membrane(GO:0060342)
0.0	0.2	GO:0070449	elongin complex(GO:0070449)
0.0	0.3	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.1	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:1990031	pinceau fiber(GO:1990031)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.5	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.0	GO:0036156	inner dynein arm(GO:0036156)
0.0	0.1	GO:0043203	axon hillock(GO:0043203)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1	0.5	GO:0004359	glutaminase activity(GO:0004359)
0.1	0.4	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.3	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	1.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.3	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0	0.1	GO:0047708	biotinidase activity(GO:0047708)
0.0	0.2	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.4	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.2	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.3	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.1	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0	0.2	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.0	0.2	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.4	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0042610	CD8 receptor binding(GO:0042610)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.3	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.6	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.1	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	0.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.3	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.4	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0	0.3	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.4	GO:0033130	acetylcholine receptor binding(GO:0033130) neuroligin family protein binding(GO:0097109)
0.0	0.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.3	GO:0031489	myosin V binding(GO:0031489)
0.0	0.2	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.0	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.0	GO:0050405	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0	0.2	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.4	GO:0008157	protein phosphatase 1 binding(GO:0008157)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.1	PID EPO PATHWAY	EPO signaling pathway
1.0	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.4	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.4	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.7	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.9	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.7	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.5	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism

Results for KLF12

Z-value: 1.13

Motif logo

Transcription factors associated with KLF12

Activity-expression correlation:

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: