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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for MECOM

Z-value: 0.72

Motif logo

Transcription factors associated with MECOM

Gene Symbol Gene ID Gene Info
ENSG00000085276.19 MDS1 and EVI1 complex locus

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MECOMhg38_v1_chr3_-_169147734_169147748-0.049.2e-01Click!

Activity profile of MECOM motif

Sorted Z-values of MECOM motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_101489940 0.94 ENST00000376162.7
integrin subunit beta like 1
chr12_-_14885845 0.93 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chr2_+_188974364 0.88 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr5_+_93583212 0.75 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr12_-_46825949 0.64 ENST00000547477.5
ENST00000447411.5
ENST00000266579.9
solute carrier family 38 member 4
chr17_-_68955332 0.59 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr3_+_99638475 0.57 ENST00000452013.5
ENST00000261037.7
ENST00000652472.1
ENST00000273342.8
ENST00000621757.1
collagen type VIII alpha 1 chain
chr10_-_20897288 0.54 ENST00000377122.9
nebulette
chrX_+_87517784 0.54 ENST00000373119.9
ENST00000373114.4
kelch like family member 4
chr1_+_171090892 0.48 ENST00000367755.9
ENST00000479749.1
flavin containing dimethylaniline monoxygenase 3
chr5_+_141223332 0.47 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr2_-_223602284 0.42 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr13_+_32031706 0.42 ENST00000542859.6
FRY microtubule binding protein
chr9_-_92482350 0.35 ENST00000375543.2
asporin
chr6_-_87095059 0.32 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr9_-_92482499 0.30 ENST00000375544.7
asporin
chr13_+_75760362 0.30 ENST00000534657.5
LIM domain 7
chr2_-_144517663 0.30 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr11_-_55936400 0.29 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr20_-_47355657 0.28 ENST00000311275.11
zinc finger MYND-type containing 8
chr6_-_53665748 0.27 ENST00000370905.4
kelch like family member 31
chr20_-_31722533 0.27 ENST00000677194.1
ENST00000434194.2
ENST00000376062.6
BCL2 like 1
chr19_+_49527988 0.26 ENST00000270645.8
reticulocalbin 3
chr6_-_52995170 0.25 ENST00000370959.1
ENST00000370963.9
glutathione S-transferase alpha 4
chr9_+_116153783 0.25 ENST00000328252.4
pappalysin 1
chr5_-_128339191 0.25 ENST00000507835.5
fibrillin 2
chr4_-_73982019 0.25 ENST00000296029.4
platelet factor 4
chr12_+_15546344 0.24 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
protein tyrosine phosphatase receptor type O
chrX_+_103628692 0.24 ENST00000372626.7
transcription elongation factor A like 1
chr1_+_74235377 0.23 ENST00000326637.8
TNNI3 interacting kinase
chr6_-_24935942 0.23 ENST00000645100.1
ENST00000643898.2
ENST00000613507.4
RHO family interacting cell polarization regulator 2
chr12_+_7062583 0.21 ENST00000542978.1
complement C1s
chrX_+_103628959 0.20 ENST00000372625.8
ENST00000372624.3
transcription elongation factor A like 1
chr1_+_103749898 0.20 ENST00000622339.5
amylase alpha 1C
chr9_+_131502789 0.19 ENST00000372228.9
ENST00000341012.13
ENST00000677216.1
ENST00000676640.1
ENST00000441334.5
ENST00000402686.8
ENST00000677029.1
ENST00000676915.1
ENST00000676803.1
ENST00000677293.1
ENST00000678303.1
ENST00000677626.1
ENST00000372220.5
ENST00000683229.1
ENST00000418774.6
ENST00000430619.2
ENST00000448212.5
ENST00000679221.1
ENST00000678785.1
protein O-mannosyltransferase 1
chr12_+_113422354 0.19 ENST00000403593.9
ENST00000553248.5
ENST00000345635.8
ENST00000547802.1
serine dehydratase like
chr1_-_97920986 0.19 ENST00000370192.8
dihydropyrimidine dehydrogenase
chr20_-_47356670 0.18 ENST00000540497.5
ENST00000461685.5
ENST00000617418.4
ENST00000435836.5
ENST00000471951.6
ENST00000352431.6
ENST00000360911.7
ENST00000458360.6
zinc finger MYND-type containing 8
chr20_-_47356721 0.18 ENST00000262975.8
ENST00000446994.6
ENST00000355972.8
ENST00000396281.8
ENST00000619049.4
ENST00000611941.4
ENST00000372023.7
zinc finger MYND-type containing 8
chrX_-_40096190 0.18 ENST00000679513.1
BCL6 corepressor
chr13_+_75760431 0.17 ENST00000321797.12
LIM domain 7
chr2_-_55923775 0.17 ENST00000438672.5
ENST00000355426.8
ENST00000440439.5
ENST00000429909.5
ENST00000424207.5
ENST00000452337.5
ENST00000439193.5
ENST00000421664.1
EGF containing fibulin extracellular matrix protein 1
chr12_+_18242955 0.16 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr15_-_78811415 0.16 ENST00000388820.5
ADAM metallopeptidase with thrombospondin type 1 motif 7
chr18_-_63158208 0.16 ENST00000678301.1
BCL2 apoptosis regulator
chr7_+_17298642 0.15 ENST00000242057.9
aryl hydrocarbon receptor
chrX_-_63755032 0.15 ENST00000624538.2
ENST00000636276.1
ENST00000624843.3
ENST00000671907.1
ENST00000624210.3
ENST00000374870.8
ENST00000635967.1
ENST00000253401.10
ENST00000672194.1
ENST00000637723.2
ENST00000637417.1
ENST00000637520.1
ENST00000374872.4
ENST00000636926.1
Cdc42 guanine nucleotide exchange factor 9
chr3_-_179266971 0.15 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr12_+_54854505 0.15 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr4_+_73853290 0.15 ENST00000226524.4
platelet factor 4 variant 1
chr5_+_168529299 0.15 ENST00000338333.5
fibrillarin like 1
chr1_+_103750406 0.15 ENST00000370079.3
amylase alpha 1C
chr14_-_24081986 0.15 ENST00000560550.1
neural retina leucine zipper
chr5_-_65624288 0.14 ENST00000381018.7
ENST00000274327.11
ENST00000231524.14
tripartite motif containing 23
chrX_-_107000185 0.13 ENST00000355610.9
MORC family CW-type zinc finger 4
chr14_-_24081928 0.13 ENST00000396995.1
neural retina leucine zipper
chr14_+_21990357 0.13 ENST00000390444.1
T cell receptor alpha variable 16
chr7_+_20615653 0.13 ENST00000404938.7
ATP binding cassette subfamily B member 5
chr12_+_53441724 0.12 ENST00000551003.5
ENST00000429243.7
ENST00000549068.5
ENST00000549740.5
ENST00000546581.5
ENST00000549581.5
ENST00000547368.5
ENST00000379786.8
ENST00000551945.5
ENST00000547717.1
proline rich 13
novel transcript
chr8_-_121641424 0.12 ENST00000303924.5
hyaluronan synthase 2
chr11_+_17295322 0.12 ENST00000458064.6
ENST00000622082.4
nucleobindin 2
chr12_-_10939263 0.11 ENST00000537503.2
taste 2 receptor member 14
chr20_+_15196834 0.11 ENST00000402914.5
mono-ADP ribosylhydrolase 2
chr5_+_119629552 0.11 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
family with sequence similarity 170 member A
chrX_+_130339941 0.11 ENST00000218197.9
solute carrier family 25 member 14
chrX_-_86047527 0.10 ENST00000615443.1
ENST00000357749.7
CHM Rab escort protein
chr7_-_120858066 0.10 ENST00000222747.8
tetraspanin 12
chr7_+_44000889 0.10 ENST00000258704.3
speedy/RINGO cell cycle regulator family member E1
chr9_-_27005659 0.10 ENST00000380055.6
leucine rich repeat containing 19
chr18_-_12656716 0.10 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr22_-_31292445 0.09 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr11_-_95923763 0.09 ENST00000497683.6
ENST00000470293.6
ENST00000674968.1
ENST00000484818.6
ENST00000675454.1
ENST00000675981.1
ENST00000674924.1
ENST00000676166.1
ENST00000676440.1
ENST00000675807.1
ENST00000495134.6
ENST00000675196.1
myotubularin related protein 2
chr9_+_79571767 0.09 ENST00000376544.7
TLE family member 4, transcriptional corepressor
chr1_-_97921042 0.09 ENST00000306031.5
dihydropyrimidine dehydrogenase
chr2_+_241350087 0.09 ENST00000451310.1
septin 2
chr8_+_133191029 0.09 ENST00000250160.11
cellular communication network factor 4
chr6_+_69232406 0.09 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr7_-_108130349 0.09 ENST00000205386.8
ENST00000418464.1
ENST00000388781.8
laminin subunit beta 4
chr18_+_34709356 0.08 ENST00000585446.1
ENST00000681241.1
dystrobrevin alpha
chr8_+_42697339 0.08 ENST00000289957.3
ENST00000534391.1
cholinergic receptor nicotinic beta 3 subunit
chr2_+_27582969 0.08 ENST00000556601.5
ENST00000413371.6
ENST00000416005.6
zinc finger protein 512
chr8_+_11494367 0.08 ENST00000259089.9
ENST00000529894.1
BLK proto-oncogene, Src family tyrosine kinase
chr1_-_237890922 0.08 ENST00000611898.4
ENST00000366570.5
zona pellucida glycoprotein 4
chr8_+_39902275 0.08 ENST00000518804.5
ENST00000519154.5
ENST00000522495.5
ENST00000522840.1
indoleamine 2,3-dioxygenase 1
chr17_-_45060988 0.08 ENST00000342350.9
dephospho-CoA kinase domain containing
chr11_+_5383812 0.08 ENST00000642046.1
olfactory receptor family 51 subfamily M member 1
chr17_-_31321603 0.08 ENST00000462804.3
ecotropic viral integration site 2A
chr2_+_27583015 0.08 ENST00000379717.5
ENST00000355467.6
ENST00000505973.1
zinc finger protein 512
novel transcript
chr15_-_55270383 0.08 ENST00000396307.6
RAB27A, member RAS oncogene family
chr14_+_24115299 0.08 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr2_+_37344594 0.08 ENST00000404976.5
ENST00000338415.8
glutaminyl-peptide cyclotransferase
chr19_-_14090695 0.07 ENST00000533683.7
sterile alpha motif domain containing 1
chr7_-_33100886 0.07 ENST00000448915.1
RP9 pre-mRNA splicing factor
chr1_-_147225309 0.07 ENST00000369272.7
ENST00000254090.9
ENST00000441068.6
flavin containing dimethylaniline monoxygenase 5
chrX_+_136648138 0.07 ENST00000370629.7
CD40 ligand
chr2_+_55519586 0.07 ENST00000339012.7
cilia and flagella associated protein 36
chr7_-_8262533 0.07 ENST00000447326.5
ENST00000406470.6
ENST00000407906.5
islet cell autoantigen 1
chr2_+_55519610 0.07 ENST00000406691.7
ENST00000407816.7
ENST00000349456.9
ENST00000403007.4
cilia and flagella associated protein 36
chr3_+_108822759 0.07 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chrX_+_136648214 0.07 ENST00000370628.2
CD40 ligand
chr9_+_79572572 0.07 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE family member 4, transcriptional corepressor
chr14_+_24114627 0.07 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr22_+_35717872 0.07 ENST00000249044.2
apolipoprotein L5
chr5_+_102865805 0.06 ENST00000346918.7
peptidylglycine alpha-amidating monooxygenase
chr3_+_108822778 0.06 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr17_-_31321743 0.06 ENST00000247270.3
ecotropic viral integration site 2A
chr7_-_101200912 0.06 ENST00000440203.6
ENST00000379423.3
ENST00000223114.9
monoacylglycerol O-acyltransferase 3
chr9_-_13175824 0.06 ENST00000545857.5
multiple PDZ domain crumbs cell polarity complex component
chr11_+_94567362 0.06 ENST00000299001.11
piwi like RNA-mediated gene silencing 4
chr7_+_91264426 0.06 ENST00000287934.4
frizzled class receptor 1
chr17_-_58353069 0.06 ENST00000580947.1
SPT4 homolog, DSIF elongation factor subunit
chr16_-_71724700 0.06 ENST00000568954.5
PH domain and leucine rich repeat protein phosphatase 2
chr6_+_31546845 0.06 ENST00000376146.8
NFKB inhibitor like 1
chrX_-_155071064 0.06 ENST00000369484.8
ENST00000369476.8
C-X9-C motif containing 4
mature T cell proliferation 1
chrX_-_43882411 0.06 ENST00000378069.5
monoamine oxidase B
chr8_-_92017292 0.06 ENST00000521553.5
RUNX1 partner transcriptional co-repressor 1
chr21_-_26967057 0.05 ENST00000284987.6
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr2_+_203706475 0.05 ENST00000374481.7
ENST00000458610.6
CD28 molecule
chr19_+_22052507 0.05 ENST00000600162.1
zinc finger protein 257
chr18_+_21363593 0.05 ENST00000580732.6
GREB1 like retinoic acid receptor coactivator
chr5_-_147782681 0.05 ENST00000616793.5
ENST00000333010.6
ENST00000265272.9
janus kinase and microtubule interacting protein 2
chr15_+_42274185 0.05 ENST00000440615.6
ENST00000318010.12
glucosidase alpha, neutral C
chr11_-_82846128 0.05 ENST00000679809.1
ENST00000680186.1
ENST00000681592.1
prolylcarboxypeptidase
chr9_+_79571956 0.05 ENST00000376552.8
TLE family member 4, transcriptional corepressor
chr2_+_171687457 0.05 ENST00000397119.8
ENST00000410079.7
ENST00000438879.5
dynein cytoplasmic 1 intermediate chain 2
chr15_+_44427793 0.05 ENST00000558966.5
ENST00000559793.5
ENST00000558968.1
CTD small phosphatase like 2
chr19_+_47994696 0.05 ENST00000596043.5
ENST00000597519.5
epididymal sperm binding protein 1
chr17_-_39152571 0.05 ENST00000415163.5
ENST00000441877.5
ENST00000444911.6
plexin domain containing 1
chr17_-_42194459 0.05 ENST00000593209.5
ENST00000588352.5
ENST00000587427.6
ENST00000414034.7
ENST00000590249.5
ENST00000428494.6
GH3 domain containing
chr9_+_127611760 0.05 ENST00000625363.2
ENST00000626539.3
syntaxin binding protein 1
chr19_+_47994625 0.05 ENST00000339841.7
epididymal sperm binding protein 1
chr9_-_127578989 0.04 ENST00000373314.7
niban apoptosis regulator 2
chr6_-_41201128 0.04 ENST00000483722.2
triggering receptor expressed on myeloid cells like 2
chr4_-_75673360 0.04 ENST00000676584.1
ENST00000678329.1
ENST00000677889.1
ENST00000357854.7
ENST00000359707.9
ENST00000676974.1
ENST00000678273.1
ENST00000677201.1
ENST00000678244.1
ENST00000677125.1
ENST00000677162.1
G3BP stress granule assembly factor 2
chr19_-_10503186 0.04 ENST00000592055.2
ENST00000171111.10
kelch like ECH associated protein 1
chr14_-_25010604 0.04 ENST00000550887.5
syntaxin binding protein 6
chr4_-_108168950 0.04 ENST00000379951.6
lymphoid enhancer binding factor 1
chr7_-_130734207 0.04 ENST00000583337.4
Kruppel like factor 14
chr7_-_76409682 0.04 ENST00000275560.4
scavenger receptor cysteine rich family member with 4 domains
chr5_+_141408032 0.04 ENST00000520790.1
protocadherin gamma subfamily B, 6
chr6_+_31547560 0.04 ENST00000376148.9
ENST00000376145.8
NFKB inhibitor like 1
chr1_-_147225568 0.04 ENST00000533174.5
ENST00000578284.5
flavin containing dimethylaniline monoxygenase 5
chr5_-_139482741 0.04 ENST00000330794.9
stimulator of interferon response cGAMP interactor 1
chr14_-_102235402 0.04 ENST00000561150.5
ENST00000522867.1
MOK protein kinase
chr2_+_43838963 0.04 ENST00000272286.4
ATP binding cassette subfamily G member 8
chr6_+_29657120 0.04 ENST00000396704.7
ENST00000416766.6
ENST00000483013.5
ENST00000490427.5
ENST00000376891.8
ENST00000376898.7
ENST00000396701.6
ENST00000494692.5
ENST00000431798.6
myelin oligodendrocyte glycoprotein
chr4_-_108168919 0.04 ENST00000265165.6
lymphoid enhancer binding factor 1
chr19_-_57145202 0.04 ENST00000269834.1
zinc finger imprinted 3
chr18_-_24311495 0.04 ENST00000357041.8
oxysterol binding protein like 1A
chr19_-_20661563 0.04 ENST00000601440.6
ENST00000291750.6
ENST00000595094.1
zinc finger protein 626
novel transcript
chr13_+_60396946 0.03 ENST00000377894.6
tudor domain containing 3
chr10_+_76318330 0.03 ENST00000496424.2
leucine rich melanocyte differentiation associated
chr4_-_75673139 0.03 ENST00000677566.1
ENST00000503660.5
ENST00000677060.1
ENST00000678552.1
G3BP stress granule assembly factor 2
chr7_+_44200960 0.03 ENST00000496112.5
ENST00000678359.1
ENST00000223369.3
ENST00000677090.1
YKT6 v-SNARE homolog
chr3_-_45842066 0.03 ENST00000445698.1
ENST00000296135.11
leucine zipper transcription factor like 1
chr3_+_109136707 0.03 ENST00000622536.6
chromosome 3 open reading frame 85
chr12_+_53442555 0.03 ENST00000549135.1
proline rich 13
chr19_+_17292583 0.03 ENST00000595444.1
ENST00000600434.5
mitochondrial ribosomal protein L34
chr3_+_119294337 0.03 ENST00000264245.9
Rho GTPase activating protein 31
chr12_-_7503744 0.03 ENST00000396620.7
ENST00000432237.3
CD163 molecule
chr5_+_96876480 0.03 ENST00000437043.8
ENST00000379904.8
endoplasmic reticulum aminopeptidase 2
chr10_+_100735390 0.03 ENST00000679374.1
paired box 2
chr15_-_26939518 0.03 ENST00000541819.6
gamma-aminobutyric acid type A receptor subunit beta3
chr5_+_126360113 0.03 ENST00000513040.5
GRAM domain containing 2B
chr12_-_95551417 0.03 ENST00000258499.8
ubiquitin specific peptidase 44
chr14_+_19743571 0.03 ENST00000642117.2
olfactory receptor family 4 subfamily Q member 3
chr16_+_71845958 0.03 ENST00000427980.7
ENST00000568581.5
ataxin 1 like
IST1 factor associated with ESCRT-III
chr11_+_60378475 0.03 ENST00000358246.5
membrane spanning 4-domains A7
chr1_+_50103903 0.03 ENST00000371827.5
ELAV like RNA binding protein 4
chr6_-_154510675 0.02 ENST00000607772.6
CNKSR family member 3
chrX_+_155997581 0.02 ENST00000244174.10
interleukin 9 receptor
chr17_+_46292733 0.02 ENST00000496930.5
leucine rich repeat containing 37A
chr2_+_36696686 0.02 ENST00000379242.7
ENST00000389975.7
vitrin
chr11_+_61222347 0.02 ENST00000378149.9
pepsinogen A4
chr8_+_133191060 0.02 ENST00000519433.1
ENST00000517423.5
ENST00000220856.6
cellular communication network factor 4
chr1_-_206117386 0.02 ENST00000367126.5
arginine vasopressin receptor 1B
chr8_-_27258414 0.02 ENST00000523048.5
stathmin 4
chr11_-_6799689 0.02 ENST00000641196.1
olfactory receptor family 6 subfamily A member 2
chr4_-_75673112 0.02 ENST00000395719.7
ENST00000677489.1
G3BP stress granule assembly factor 2
chr6_+_152697888 0.02 ENST00000367245.5
ENST00000529453.1
MYC target 1
chr15_+_70892809 0.02 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr7_-_15561986 0.02 ENST00000342526.8
alkylglycerol monooxygenase
chr11_+_17351786 0.02 ENST00000338965.9
natural killer cell cytotoxicity receptor 3 ligand 1
chr6_+_33428223 0.02 ENST00000682587.1
synaptic Ras GTPase activating protein 1
chr2_+_171687501 0.02 ENST00000508530.5
dynein cytoplasmic 1 intermediate chain 2
chr11_-_18634332 0.02 ENST00000336349.6
SPT2 chromatin protein domain containing 1
chr10_+_104275126 0.02 ENST00000369707.2
glutathione S-transferase omega 2
chr1_+_192158448 0.02 ENST00000367460.4
regulator of G protein signaling 18
chrX_-_9295682 0.02 ENST00000651278.1
family with sequence similarity 9 member B
chr7_+_124476371 0.02 ENST00000473520.1
SSU72 pseudogene 8
chr19_-_48391505 0.02 ENST00000600980.1
ENST00000330720.7
KDEL endoplasmic reticulum protein retention receptor 1
chr1_-_161223408 0.02 ENST00000491350.1
apolipoprotein A2
chr12_-_7503841 0.02 ENST00000359156.8
CD163 molecule
chr2_+_171687672 0.01 ENST00000409197.5
ENST00000456808.5
ENST00000409317.5
ENST00000409773.5
ENST00000411953.5
ENST00000409453.5
dynein cytoplasmic 1 intermediate chain 2
chr19_+_47035300 0.01 ENST00000439365.6
ENST00000594670.1
neuronal PAS domain protein 1
chr15_-_40108861 0.01 ENST00000354670.9
ENST00000559701.5
ENST00000557870.1
ENST00000558774.5
Bcl2 modifying factor
chr10_-_29634964 0.01 ENST00000375398.6
ENST00000355867.8
supervillin
chr20_+_45629717 0.01 ENST00000372643.4
WAP four-disulfide core domain 10A
chr4_-_77075967 0.01 ENST00000237654.9
cyclin I
chr12_+_71686061 0.01 ENST00000266673.10
ENST00000550524.5
transmembrane protein 19

Network of associatons between targets according to the STRING database.

First level regulatory network of MECOM

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.8 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.3 GO:0019483 uracil catabolic process(GO:0006212) beta-alanine biosynthetic process(GO:0019483)
0.1 0.2 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0000494 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.2 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.2 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0045653 negative regulation of MHC class II biosynthetic process(GO:0045347) negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.8 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.0 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630) regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.0 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.6 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.2 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0071547 piP-body(GO:0071547)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)