Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
ENSG00000185155.12 | Mix paired-like homeobox | |
ENSG00000169840.5 | GS homeobox 1 | |
ENSG00000188909.5 | brain specific homeobox | |
ENSG00000106511.6 | mesenchyme homeobox 2 | |
ENSG00000121454.6 | LIM homeobox 4 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
LHX4 | hg38_v1_chr1_+_180230257_180230291 | 0.38 | 3.5e-01 | Click! |
MIXL1 | hg38_v1_chr1_+_226223618_226223670 | 0.37 | 3.7e-01 | Click! |
GSX1 | hg38_v1_chr13_+_27792479_27792485 | 0.24 | 5.6e-01 | Click! |
MEOX2 | hg38_v1_chr7_-_15686671_15686689 | 0.16 | 7.1e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 8.7 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
0.1 | 8.3 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
0.4 | 8.0 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
0.3 | 7.6 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
0.1 | 7.5 | GO:0070268 | cornification(GO:0070268) |
0.0 | 3.6 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
0.0 | 2.9 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
0.0 | 2.8 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.3 | 2.7 | GO:2000620 | innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.2 | 2.5 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 8.1 | GO:0001772 | immunological synapse(GO:0001772) |
0.1 | 7.5 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.2 | 5.7 | GO:0030057 | desmosome(GO:0030057) |
0.0 | 3.0 | GO:0005875 | microtubule associated complex(GO:0005875) |
0.8 | 2.3 | GO:0060187 | cell pole(GO:0060187) |
0.2 | 2.3 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
0.0 | 2.3 | GO:0030673 | axolemma(GO:0030673) |
0.2 | 2.2 | GO:0016013 | syntrophin complex(GO:0016013) |
0.0 | 2.2 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 1.8 | GO:0031258 | lamellipodium membrane(GO:0031258) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 9.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.3 | 8.1 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.1 | 7.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.3 | 7.6 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.2 | 7.5 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.2 | 4.8 | GO:0005549 | odorant binding(GO:0005549) |
0.1 | 4.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.3 | 3.9 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.3 | 2.9 | GO:0004064 | arylesterase activity(GO:0004064) |
0.1 | 2.7 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 10.3 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.2 | 6.5 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
0.0 | 6.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 3.9 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.1 | 3.2 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 3.0 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 2.1 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 2.1 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
0.0 | 1.9 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.0 | 1.7 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 8.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.1 | 8.0 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.2 | 4.6 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 4.4 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
0.2 | 2.9 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
0.1 | 2.3 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.0 | 2.2 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.1 | 1.8 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
0.1 | 1.7 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
0.1 | 1.6 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |