Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
ENSG00000108788.12 | MAX dimerization protein MLX | |
ENSG00000105698.16 | upstream transcription factor 2, c-fos interacting | |
ENSG00000158773.14 | upstream transcription factor 1 | |
ENSG00000075891.23 | paired box 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
USF1 | hg38_v1_chr1_-_161044941_161044998, hg38_v1_chr1_-_161045961_161045988 | -0.55 | 1.6e-01 | Click! |
USF2 | hg38_v1_chr19_+_35269065_35269140 | 0.45 | 2.6e-01 | Click! |
PAX2 | hg38_v1_chr10_+_100745711_100745790, hg38_v1_chr10_+_100745570_100745588, hg38_v1_chr10_+_100735390_100735402 | -0.31 | 4.6e-01 | Click! |
MLX | hg38_v1_chr17_+_42567084_42567125 | -0.21 | 6.2e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 5.4 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.4 | 5.3 | GO:0060155 | platelet dense granule organization(GO:0060155) |
1.3 | 4.0 | GO:0002339 | B cell selection(GO:0002339) positive regulation of apoptotic DNA fragmentation(GO:1902512) |
0.7 | 3.7 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
0.0 | 3.6 | GO:0006457 | protein folding(GO:0006457) |
0.3 | 3.4 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
0.2 | 2.7 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.4 | 2.5 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
0.4 | 2.5 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
0.6 | 2.4 | GO:0035407 | histone H3-T11 phosphorylation(GO:0035407) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 6.9 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
0.1 | 6.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.2 | 5.4 | GO:0031083 | BLOC-1 complex(GO:0031083) |
0.0 | 4.3 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.3 | 4.0 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.0 | 3.3 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 3.1 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
0.2 | 2.7 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.4 | 2.4 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.0 | 2.2 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 5.8 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.1 | 5.8 | GO:0005507 | copper ion binding(GO:0005507) |
0.1 | 5.7 | GO:0050699 | WW domain binding(GO:0050699) |
0.4 | 5.4 | GO:0031419 | cobalamin binding(GO:0031419) |
0.0 | 4.1 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.3 | 4.0 | GO:0051434 | BH3 domain binding(GO:0051434) |
0.7 | 3.7 | GO:0004370 | glycerol kinase activity(GO:0004370) |
0.6 | 3.1 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.1 | 2.5 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.6 | 2.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 7.2 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.2 | 4.0 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.0 | 4.0 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.1 | 3.7 | PID MYC PATHWAY | C-MYC pathway |
0.0 | 3.2 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.1 | 2.3 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
0.0 | 2.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
0.0 | 2.0 | PID MTOR 4PATHWAY | mTOR signaling pathway |
0.0 | 2.0 | PID E2F PATHWAY | E2F transcription factor network |
0.0 | 1.9 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 7.7 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
0.1 | 6.6 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
0.1 | 4.1 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
0.0 | 3.2 | REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION | Genes involved in Cyclin E associated events during G1/S transition |
0.1 | 2.7 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 2.7 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
0.0 | 2.6 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.0 | 2.3 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
0.1 | 2.2 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.1 | 2.1 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |