Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
ENSG00000070444.15 | MAX network transcriptional repressor | |
ENSG00000164683.18 | hes related family bHLH transcription factor with YRPW motif 1 | |
ENSG00000135547.9 | hes related family bHLH transcription factor with YRPW motif 2 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
HEY1 | hg38_v1_chr8_-_79767843_79767867, hg38_v1_chr8_-_79767462_79767776 | 0.70 | 5.3e-02 | Click! |
HEY2 | hg38_v1_chr6_+_125749623_125749655 | 0.37 | 3.7e-01 | Click! |
MNT | hg38_v1_chr17_-_2401038_2401104 | 0.27 | 5.1e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 4.8 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
0.2 | 3.1 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
0.2 | 2.9 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.1 | 2.8 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
0.0 | 2.2 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
0.0 | 2.1 | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774) |
0.1 | 1.7 | GO:0051639 | actin filament network formation(GO:0051639) |
0.1 | 1.7 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
0.5 | 1.6 | GO:0048817 | negative regulation of hair follicle maturation(GO:0048817) |
0.5 | 1.6 | GO:0034147 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 4.9 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.0 | 3.5 | GO:0035578 | azurophil granule lumen(GO:0035578) |
0.0 | 3.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 3.1 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.1 | 3.0 | GO:0001772 | immunological synapse(GO:0001772) |
0.0 | 2.4 | GO:0070821 | tertiary granule membrane(GO:0070821) |
0.0 | 2.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.2 | 1.6 | GO:1905202 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
0.0 | 1.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.1 | 1.4 | GO:0035748 | myelin sheath abaxonal region(GO:0035748) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 4.9 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.0 | 3.6 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.1 | 3.0 | GO:0016502 | purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) |
0.2 | 2.9 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.1 | 2.6 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.0 | 2.3 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.3 | 2.0 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.0 | 2.0 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.2 | 1.6 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
0.1 | 1.6 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.7 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 1.8 | PID BMP PATHWAY | BMP receptor signaling |
0.0 | 1.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
0.0 | 1.2 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
0.0 | 1.1 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 1.1 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
0.0 | 0.9 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 0.9 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
0.0 | 0.8 | PID FANCONI PATHWAY | Fanconi anemia pathway |
0.0 | 0.8 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.1 | 3.3 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
0.2 | 3.0 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
0.1 | 2.7 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.0 | 2.0 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 1.7 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
0.0 | 1.6 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.0 | 1.5 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
0.0 | 1.5 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
0.0 | 1.4 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |