Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
ENSG00000119950.21 | MAX interactor 1, dimerization protein | |
ENSG00000136997.21 | MYC proto-oncogene, bHLH transcription factor | |
ENSG00000134323.12 | MYCN proto-oncogene, bHLH transcription factor |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
MYC | hg38_v1_chr8_+_127736046_127736084, hg38_v1_chr8_+_127736220_127736241, hg38_v1_chr8_+_127735597_127735659, hg38_v1_chr8_+_127737610_127737626 | 0.82 | 1.3e-02 | Click! |
MYCN | hg38_v1_chr2_+_15940537_15940566 | 0.75 | 3.2e-02 | Click! |
MXI1 | hg38_v1_chr10_+_110226805_110227679 | -0.13 | 7.6e-01 | Click! |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr22_+_39994926 Show fit | 7.90 |
ENST00000333407.11
|
family with sequence similarity 83 member F |
|
chr20_+_59628609 Show fit | 5.18 |
ENST00000541461.5
|
phosphatase and actin regulator 3 |
|
chr12_-_31325494 Show fit | 4.94 |
ENST00000543615.1
|
SIN3-HDAC complex associated factor |
|
chr19_+_10654261 Show fit | 4.81 |
ENST00000449870.5
|
interleukin enhancer binding factor 3 |
|
chr8_+_94641145 Show fit | 4.73 |
ENST00000433389.8
ENST00000358397.9 |
epithelial splicing regulatory protein 1 |
|
chr2_-_110115811 Show fit | 4.73 |
ENST00000272462.3
|
mal, T cell differentiation protein like |
|
chr8_+_94641199 Show fit | 4.69 |
ENST00000646773.1
ENST00000454170.7 |
epithelial splicing regulatory protein 1 |
|
chr8_+_94641074 Show fit | 4.62 |
ENST00000423620.6
|
epithelial splicing regulatory protein 1 |
|
chr7_+_69598465 Show fit | 4.61 |
ENST00000342771.10
|
activator of transcription and developmental regulator AUTS2 |
|
chr16_+_68645290 Show fit | 4.57 |
ENST00000264012.9
|
cadherin 3 |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 20.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.1 | 14.9 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
0.3 | 10.5 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
3.2 | 9.5 | GO:0048817 | negative regulation of hair follicle maturation(GO:0048817) |
0.1 | 9.0 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.8 | 8.6 | GO:0035524 | proline transmembrane transport(GO:0035524) |
0.2 | 8.5 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.2 | 8.5 | GO:0006400 | tRNA modification(GO:0006400) |
0.9 | 8.3 | GO:0098582 | innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.5 | 8.3 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 52.7 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.0 | 20.0 | GO:0005730 | nucleolus(GO:0005730) |
0.0 | 15.8 | GO:0016604 | nuclear body(GO:0016604) |
0.0 | 15.6 | GO:0031965 | nuclear membrane(GO:0031965) |
0.0 | 14.8 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.1 | 12.9 | GO:0001650 | fibrillar center(GO:0001650) |
0.2 | 12.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.3 | 10.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.5 | 8.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.3 | 8.2 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 14.4 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
0.1 | 12.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.1 | 12.0 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.5 | 11.6 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.1 | 8.8 | GO:0017048 | Rho GTPase binding(GO:0017048) |
1.4 | 8.5 | GO:0005298 | proline:sodium symporter activity(GO:0005298) |
0.1 | 8.5 | GO:0004896 | cytokine receptor activity(GO:0004896) |
0.7 | 7.6 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.2 | 7.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.3 | 7.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 21.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 7.9 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.1 | 5.7 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
0.1 | 5.7 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
0.1 | 5.0 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
0.1 | 5.0 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.1 | 4.8 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.1 | 4.5 | PID BMP PATHWAY | BMP receptor signaling |
0.1 | 3.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 3.7 | PID CD40 PATHWAY | CD40/CD40L signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 11.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
0.6 | 9.5 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
0.3 | 9.3 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
0.1 | 9.2 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
0.5 | 9.0 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
0.1 | 8.6 | REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | Genes involved in Processing of Capped Intron-Containing Pre-mRNA |
0.4 | 8.5 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
0.4 | 7.7 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
0.2 | 6.7 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.1 | 6.3 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |