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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NFATC1

Z-value: 0.84

Motif logo

Transcription factors associated with NFATC1

Gene Symbol Gene ID Gene Info
ENSG00000131196.18 nuclear factor of activated T cells 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC1hg38_v1_chr18_+_79395856_79395939-0.611.1e-01Click!

Activity profile of NFATC1 motif

Sorted Z-values of NFATC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_91946989 2.29 ENST00000556154.5
fibulin 5
chr14_-_91947383 2.02 ENST00000267620.14
fibulin 5
chr2_+_188974364 1.29 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr12_-_91179472 1.06 ENST00000550099.5
ENST00000546391.5
decorin
chr12_-_91179355 1.03 ENST00000550563.5
ENST00000546370.5
decorin
chr7_+_100602344 0.68 ENST00000223061.6
procollagen C-endopeptidase enhancer
chr15_+_32717994 0.64 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chrX_+_153494970 0.62 ENST00000331595.9
ENST00000431891.1
biglycan
chr13_-_67230313 0.59 ENST00000377865.7
protocadherin 9
chr18_-_28036585 0.59 ENST00000399380.7
cadherin 2
chr13_-_67230377 0.55 ENST00000544246.5
ENST00000377861.4
protocadherin 9
chr1_+_162632454 0.53 ENST00000367921.8
ENST00000367922.7
discoidin domain receptor tyrosine kinase 2
chr2_-_162242998 0.50 ENST00000627638.2
ENST00000447386.5
fibroblast activation protein alpha
chr5_-_111758061 0.46 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
neuronal regeneration related protein
chr8_-_13514821 0.45 ENST00000276297.9
DLC1 Rho GTPase activating protein
chr1_-_153544997 0.44 ENST00000368715.5
S100 calcium binding protein A4
chr3_+_148730100 0.44 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr5_-_159099684 0.41 ENST00000380654.8
EBF transcription factor 1
chr12_+_78863962 0.41 ENST00000393240.7
synaptotagmin 1
chr5_-_159099745 0.41 ENST00000517373.1
EBF transcription factor 1
chr17_-_15260752 0.40 ENST00000676329.1
ENST00000675551.1
ENST00000644020.1
ENST00000674947.1
peripheral myelin protein 22
chr5_-_159099909 0.39 ENST00000313708.11
EBF transcription factor 1
chr9_+_88991440 0.38 ENST00000358157.3
sphingosine-1-phosphate receptor 3
chr8_-_13514744 0.38 ENST00000316609.9
DLC1 Rho GTPase activating protein
chr3_-_71583683 0.36 ENST00000649631.1
ENST00000648718.1
forkhead box P1
chr9_-_16870702 0.34 ENST00000380667.6
ENST00000545497.5
ENST00000486514.5
basonuclin 2
chr10_+_92831153 0.34 ENST00000672817.1
exocyst complex component 6
chr10_-_103452384 0.34 ENST00000369788.7
calcium homeostasis modulator family member 2
chr8_+_76681208 0.34 ENST00000651372.2
zinc finger homeobox 4
chr16_+_15434577 0.34 ENST00000300006.9
bMERB domain containing 1
chr16_+_15434475 0.34 ENST00000566490.5
bMERB domain containing 1
chr10_+_103277129 0.33 ENST00000369849.9
internexin neuronal intermediate filament protein alpha
chr6_-_56851888 0.32 ENST00000312431.10
ENST00000520645.5
dystonin
chr10_-_103452356 0.32 ENST00000260743.10
calcium homeostasis modulator family member 2
chr3_-_15797930 0.30 ENST00000683139.1
ankyrin repeat domain 28
chr11_-_102530738 0.30 ENST00000260227.5
matrix metallopeptidase 7
chr1_+_78649818 0.29 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr3_-_71583713 0.29 ENST00000649528.3
ENST00000471386.3
ENST00000493089.7
forkhead box P1
chr2_-_213151590 0.28 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr8_-_121641424 0.27 ENST00000303924.5
hyaluronan synthase 2
chr5_+_141350081 0.27 ENST00000523390.2
ENST00000611598.1
protocadherin gamma subfamily B, 1
chr9_-_20622479 0.25 ENST00000380338.9
MLLT3 super elongation complex subunit
chr2_-_162243375 0.24 ENST00000188790.9
ENST00000443424.5
fibroblast activation protein alpha
chr7_+_120988683 0.23 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr5_+_149141483 0.23 ENST00000326685.11
ENST00000309868.12
actin binding LIM protein family member 3
chr5_+_149141573 0.22 ENST00000506113.5
actin binding LIM protein family member 3
chr3_-_71583592 0.22 ENST00000650156.1
ENST00000649596.1
forkhead box P1
chr7_-_29146436 0.22 ENST00000396276.7
carboxypeptidase vitellogenic like
chr3_+_69763726 0.21 ENST00000448226.9
melanocyte inducing transcription factor
chr15_+_92900189 0.21 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chr8_-_130386864 0.21 ENST00000521426.5
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chrX_+_22136552 0.20 ENST00000682888.1
ENST00000684356.1
phosphate regulating endopeptidase homolog X-linked
chr8_+_38974212 0.19 ENST00000302495.5
HtrA serine peptidase 4
chr17_-_31321603 0.19 ENST00000462804.3
ecotropic viral integration site 2A
chr12_-_10453330 0.19 ENST00000347831.9
ENST00000359151.8
killer cell lectin like receptor C1
chr3_-_127822455 0.19 ENST00000265052.10
monoglyceride lipase
chr4_-_158173042 0.18 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr17_-_31321743 0.18 ENST00000247270.3
ecotropic viral integration site 2A
chr3_-_115147237 0.18 ENST00000357258.8
zinc finger and BTB domain containing 20
chr9_-_70869076 0.18 ENST00000677594.1
transient receptor potential cation channel subfamily M member 3
chr3_-_115147277 0.18 ENST00000675478.1
zinc finger and BTB domain containing 20
chr4_-_158173004 0.17 ENST00000585682.6
golgi associated kinase 1B
chr5_-_160685379 0.17 ENST00000642502.1
ATPase phospholipid transporting 10B (putative)
chr1_+_85580751 0.17 ENST00000451137.7
cellular communication network factor 1
chr4_+_122339221 0.17 ENST00000442707.1
KIAA1109
chr12_+_1820558 0.17 ENST00000299194.6
leucine rich repeats and transmembrane domains 2
chr12_+_1820255 0.17 ENST00000543818.5
leucine rich repeats and transmembrane domains 2
chr16_-_18876305 0.17 ENST00000563235.5
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chrX_-_100410264 0.16 ENST00000373034.8
protocadherin 19
chr14_+_104581141 0.16 ENST00000410013.1
chromosome 14 open reading frame 180
chr4_-_41748713 0.16 ENST00000226382.4
paired like homeobox 2B
chr11_-_58844695 0.16 ENST00000287275.6
glycine-N-acyltransferase like 2
chrX_-_63785510 0.16 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr3_+_69084929 0.16 ENST00000273258.4
ADP ribosylation factor like GTPase 6 interacting protein 5
chr12_-_91179517 0.16 ENST00000551354.1
decorin
chr4_-_177442427 0.16 ENST00000264595.7
aspartylglucosaminidase
chr12_+_1820617 0.16 ENST00000535041.5
leucine rich repeats and transmembrane domains 2
chr3_-_157533594 0.16 ENST00000487753.5
ENST00000489602.1
ENST00000461299.5
ENST00000479987.5
ventricular zone expressed PH domain containing 1
chr3_+_152300135 0.15 ENST00000465907.6
ENST00000492948.5
ENST00000485509.5
ENST00000464596.5
muscleblind like splicing regulator 1
chr7_-_100896123 0.15 ENST00000428317.7
acetylcholinesterase (Cartwright blood group)
chr10_-_78029487 0.15 ENST00000372371.8
RNA polymerase III subunit A
chr2_+_33476640 0.15 ENST00000425210.5
ENST00000444784.5
ENST00000423159.5
ENST00000403687.8
RAS guanyl releasing protein 3
chr2_+_11677587 0.15 ENST00000449576.6
lipin 1
chr14_+_50560137 0.15 ENST00000358385.12
atlastin GTPase 1
chr5_-_55173173 0.15 ENST00000296733.5
ENST00000322374.10
ENST00000381375.7
cell division cycle 20B
chr9_-_70869029 0.14 ENST00000361823.9
ENST00000377101.5
ENST00000360823.6
ENST00000377105.5
transient receptor potential cation channel subfamily M member 3
chr19_-_43883964 0.14 ENST00000587539.2
zinc finger protein 404
chr22_+_37675629 0.14 ENST00000215909.10
galectin 1
chr5_+_50666612 0.13 ENST00000281631.10
poly(ADP-ribose) polymerase family member 8
chr12_+_25958891 0.13 ENST00000381352.7
ENST00000535907.5
ENST00000405154.6
ENST00000615708.4
Ras association domain family member 8
chr4_-_16083714 0.13 ENST00000508167.5
prominin 1
chr3_+_69084973 0.13 ENST00000478935.1
ADP ribosylation factor like GTPase 6 interacting protein 5
chr5_+_71719267 0.13 ENST00000296777.5
CART prepropeptide
chr10_-_102837406 0.13 ENST00000369887.4
ENST00000638272.1
ENST00000639393.1
ENST00000638971.1
ENST00000638190.1
cytochrome P450 family 17 subfamily A member 1
chr5_+_140401808 0.13 ENST00000616482.4
ENST00000297183.10
ENST00000360839.7
ENST00000421134.5
ENST00000394723.7
ENST00000511151.5
ankyrin repeat and KH domain containing 1
chr4_-_16083695 0.13 ENST00000510224.5
prominin 1
chr4_+_26584064 0.12 ENST00000264866.9
ENST00000505206.5
ENST00000511789.5
TBC1 domain family member 19
chr5_-_74641419 0.12 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ectodermal-neural cortex 1
chr1_-_150808251 0.12 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
cathepsin K
chr7_-_120858066 0.12 ENST00000222747.8
tetraspanin 12
chr14_+_80955577 0.12 ENST00000642209.1
ENST00000298171.7
thyroid stimulating hormone receptor
chr10_-_63269057 0.12 ENST00000542921.5
jumonji domain containing 1C
chr16_+_1533654 0.12 ENST00000566264.2
transmembrane protein 204
chr16_-_21425278 0.12 ENST00000504841.6
ENST00000419180.6
nuclear pore complex interacting protein family member B3
chr4_-_82844418 0.12 ENST00000503937.5
SEC31 homolog A, COPII coat complex component
chrX_+_41333905 0.12 ENST00000457138.7
ENST00000643821.1
DEAD-box helicase 3 X-linked
chr2_-_40452046 0.12 ENST00000406785.6
solute carrier family 8 member A1
chr6_+_10528326 0.12 ENST00000379597.7
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr7_+_134866831 0.12 ENST00000435928.1
caldesmon 1
chr14_-_89417148 0.12 ENST00000557258.6
forkhead box N3
chrX_-_13817346 0.12 ENST00000356942.9
glycoprotein M6B
chr3_-_15798184 0.12 ENST00000624145.3
ankyrin repeat domain 28
chr10_-_13099652 0.12 ENST00000378839.1
coiled-coil domain containing 3
chr3_-_179259208 0.12 ENST00000485523.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr2_-_55334529 0.11 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chr10_-_90921079 0.11 ENST00000371697.4
ankyrin repeat domain 1
chr11_-_2161158 0.11 ENST00000421783.1
ENST00000397262.5
ENST00000381330.5
ENST00000250971.7
ENST00000397270.1
insulin
INS-IGF2 readthrough
chr1_+_61082702 0.11 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chrX_+_9560465 0.11 ENST00000647060.1
transducin beta like 1 X-linked
chr15_-_43493076 0.11 ENST00000413546.1
tumor protein p53 binding protein 1
chr7_+_20647388 0.11 ENST00000258738.10
ATP binding cassette subfamily B member 5
chr1_-_27490045 0.11 ENST00000536657.1
WASP family member 2
chr1_-_154192058 0.11 ENST00000271850.11
ENST00000368530.7
ENST00000651641.1
tropomyosin 3
chr14_+_58427970 0.11 ENST00000261244.9
KIAA0586
chr6_+_32439866 0.11 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr10_+_102776237 0.11 ENST00000369889.5
WW domain binding protein 1 like
chr6_-_135498417 0.11 ENST00000681022.1
ENST00000680033.1
Abelson helper integration site 1
chr2_+_46699241 0.11 ENST00000394861.3
suppressor of cytokine signaling 5
chr17_+_34255274 0.11 ENST00000580907.5
ENST00000225831.4
C-C motif chemokine ligand 2
chr15_-_43493105 0.11 ENST00000382039.7
ENST00000450115.6
ENST00000382044.9
tumor protein p53 binding protein 1
chr1_+_15476099 0.10 ENST00000375910.8
chymotrypsin like elastase 2B
chr8_+_84183534 0.10 ENST00000518566.5
RALY RNA binding protein like
chr6_-_79234713 0.10 ENST00000620514.1
high mobility group nucleosomal binding domain 3
chr6_-_79234619 0.10 ENST00000344726.9
ENST00000275036.11
high mobility group nucleosomal binding domain 3
chr9_+_35161951 0.10 ENST00000617908.4
ENST00000619578.4
unc-13 homolog B
chr12_+_26195543 0.10 ENST00000242729.7
sarcospan
chr17_+_7425606 0.10 ENST00000333870.8
ENST00000574034.1
SPEM family member 2
chr9_-_35815034 0.10 ENST00000259667.6
histidine triad nucleotide binding protein 2
chr9_+_121299793 0.10 ENST00000373818.8
gelsolin
chr4_+_41613476 0.10 ENST00000508466.1
LIM and calponin homology domains 1
chr17_+_81528370 0.10 ENST00000417245.7
ENST00000334850.7
fascin actin-bundling protein 2, retinal
chr9_+_35162000 0.10 ENST00000396787.5
ENST00000378495.7
ENST00000635942.1
ENST00000378496.8
unc-13 homolog B
chr1_-_41662298 0.09 ENST00000643665.1
HIVEP zinc finger 3
chr19_-_18281612 0.09 ENST00000252818.5
JunD proto-oncogene, AP-1 transcription factor subunit
chr3_-_179266971 0.09 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr5_+_140401860 0.09 ENST00000532219.5
ENST00000394722.7
ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1
chr19_-_14062028 0.09 ENST00000669674.2
paralemmin 3
chr2_+_200526120 0.09 ENST00000409203.3
ENST00000357799.9
shugoshin 2
chr11_+_118883884 0.09 ENST00000292174.5
C-X-C motif chemokine receptor 5
chr16_+_28638065 0.09 ENST00000683297.1
nuclear pore complex interacting protein family member B8
chr12_-_119804472 0.09 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chr4_+_158521937 0.09 ENST00000343542.9
ENST00000470033.2
relaxin family peptide receptor 1
chr17_-_51046868 0.09 ENST00000510283.5
ENST00000510855.1
sperm associated antigen 9
chr12_+_26195313 0.09 ENST00000422622.3
sarcospan
chr2_+_172085499 0.09 ENST00000361725.5
ENST00000341900.6
distal-less homeobox 1
chr16_-_69384747 0.09 ENST00000566257.5
telomeric repeat binding factor 2
chr5_+_141408032 0.09 ENST00000520790.1
protocadherin gamma subfamily B, 6
chr17_-_41060109 0.09 ENST00000391418.3
keratin associated protein 2-3
chrX_-_120629936 0.09 ENST00000371313.2
ENST00000304661.6
C1GALT1 specific chaperone 1
chr6_+_39792298 0.09 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr19_-_51082883 0.09 ENST00000650543.2
kallikrein related peptidase 14
chr3_-_136752361 0.09 ENST00000480733.1
ENST00000629124.2
ENST00000383202.7
ENST00000236698.9
ENST00000434713.6
stromal antigen 1
chr15_-_34969688 0.08 ENST00000156471.10
aquarius intron-binding spliceosomal factor
chr11_+_121129964 0.08 ENST00000645008.1
tectorin alpha
chr2_-_55296361 0.08 ENST00000647547.1
coiled-coil domain containing 88A
chr12_+_8157034 0.08 ENST00000396570.7
zinc finger protein 705A
chr8_-_11201799 0.08 ENST00000416569.3
XK related 6
chr14_-_24429665 0.08 ENST00000267406.11
cerebellin 3 precursor
chr3_+_46354072 0.08 ENST00000445132.3
ENST00000421659.1
C-C motif chemokine receptor 2
chrX_-_43973382 0.08 ENST00000642620.1
ENST00000647044.1
norrin cystine knot growth factor NDP
chr1_-_182400660 0.08 ENST00000367565.2
transmembrane epididymal protein 1
chr3_-_71304741 0.08 ENST00000484350.5
forkhead box P1
chrX_-_19887585 0.08 ENST00000397821.8
SH3 domain containing kinase binding protein 1
chr5_+_50666660 0.08 ENST00000515175.6
poly(ADP-ribose) polymerase family member 8
chr15_-_32455634 0.08 ENST00000509311.7
golgin A8 family member O
chr3_+_152299570 0.08 ENST00000485910.5
ENST00000463374.5
muscleblind like splicing regulator 1
chr7_-_6706843 0.08 ENST00000394917.3
ENST00000342651.9
ENST00000405858.6
zinc finger protein 12
chr14_-_35121950 0.08 ENST00000554361.5
ENST00000261475.10
protein phosphatase 2 regulatory subunit B''gamma
chr1_+_171512032 0.08 ENST00000426496.6
proline rich coiled-coil 2C
chr3_-_65597886 0.08 ENST00000460329.6
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_+_11806096 0.08 ENST00000312413.10
ENST00000346436.11
chloride voltage-gated channel 6
chr1_+_36084079 0.08 ENST00000207457.8
tektin 2
chrX_+_103356446 0.08 ENST00000372656.5
ENST00000372661.6
ENST00000646896.1
transcription elongation factor A like 9
chr17_-_37609361 0.08 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr3_-_183099508 0.07 ENST00000476176.5
methylcrotonoyl-CoA carboxylase 1
chr1_-_120051714 0.07 ENST00000579475.7
notch receptor 2
chr3_-_179071742 0.07 ENST00000311417.7
ENST00000652290.1
zinc finger matrin-type 3
chr12_+_6772512 0.07 ENST00000441671.6
ENST00000203629.3
lymphocyte activating 3
chr1_-_169630115 0.07 ENST00000263686.11
ENST00000367788.6
selectin P
chr3_-_132684685 0.07 ENST00000512094.5
ENST00000632629.1
nephrocystin 3
NPHP3-ACAD11 readthrough (NMD candidate)
chrX_+_134807217 0.07 ENST00000482240.5
ENST00000475361.1
ENST00000645433.2
ENST00000494709.1
PABIR family member 3
chr9_-_14314519 0.07 ENST00000397581.6
nuclear factor I B
chr19_+_10086787 0.07 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr1_+_168576595 0.07 ENST00000367818.4
X-C motif chemokine ligand 1
chr16_+_22513523 0.07 ENST00000538606.5
ENST00000451409.5
ENST00000424340.5
ENST00000517539.5
ENST00000528249.5
nuclear pore complex interacting protein family member B5
chr16_-_21857418 0.07 ENST00000415645.6
nuclear pore complex interacting protein family member B4
chr15_+_32593456 0.07 ENST00000448387.6
ENST00000569659.5
golgin A8 family member N
chr3_-_158672612 0.07 ENST00000264265.4
latexin
chrX_-_13817027 0.06 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr12_-_58920465 0.06 ENST00000320743.8
leucine rich repeats and immunoglobulin like domains 3

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.6 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.2 1.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 0.7 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 2.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 1.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.8 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.1 GO:0048058 compound eye corneal lens development(GO:0048058)
0.0 0.3 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 0.1 GO:0039023 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.5 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0090264 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
0.0 0.1 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:2000537 positive regulation of thymocyte migration(GO:2000412) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0061443 endocardial cell fate commitment(GO:0060957) endocardial cushion cell differentiation(GO:0061443) endocardial cushion cell fate commitment(GO:0061445)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:2000724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.3 GO:0044849 estrous cycle(GO:0044849)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.3 GO:0071953 elastic fiber(GO:0071953)
0.2 2.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.7 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.2 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0043218 compact myelin(GO:0043218)
0.0 1.4 GO:0044291 cell-cell contact zone(GO:0044291)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 1.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.6 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 5.7 GO:0005178 integrin binding(GO:0005178)
0.0 2.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.0 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 0.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0043273 CTPase activity(GO:0043273)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.7 GO:0016504 peptidase activator activity(GO:0016504)
0.0 1.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.0 GO:0033265 choline binding(GO:0033265)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 4.5 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling