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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NKX2-3

Z-value: 0.79

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Transcription factors associated with NKX2-3

Gene Symbol Gene ID Gene Info
ENSG00000119919.11 NK2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-3hg38_v1_chr10_+_99532927_995329530.452.6e-01Click!

Activity profile of NKX2-3 motif

Sorted Z-values of NKX2-3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_140834230 0.65 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr4_-_36244438 0.48 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_34755039 0.48 ENST00000338513.1
gap junction protein beta 5
chr20_+_59835853 0.47 ENST00000492611.5
phosphatase and actin regulator 3
chr5_+_36608146 0.46 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr3_-_111595339 0.44 ENST00000317012.5
zinc finger BED-type containing 2
chr19_+_35106510 0.39 ENST00000648240.1
novel protein
chr2_-_162318129 0.38 ENST00000679938.1
interferon induced with helicase C domain 1
chr4_-_89837106 0.38 ENST00000394986.5
ENST00000394991.8
ENST00000506244.5
ENST00000394989.6
ENST00000673902.1
ENST00000674129.1
synuclein alpha
chr4_-_89836213 0.37 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr4_-_89837076 0.36 ENST00000506691.1
synuclein alpha
chr4_-_99352754 0.34 ENST00000639454.1
alcohol dehydrogenase 1B (class I), beta polypeptide
chr19_-_51002527 0.32 ENST00000595238.1
ENST00000600767.5
kallikrein related peptidase 8
chr4_-_89836963 0.32 ENST00000420646.6
ENST00000673718.1
synuclein alpha
chr18_+_63777773 0.29 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr19_+_44905785 0.29 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr9_-_92404559 0.28 ENST00000262551.8
ENST00000375561.10
osteoglycin
chr4_-_99352730 0.27 ENST00000510055.5
ENST00000515683.6
ENST00000511397.3
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr2_+_190180447 0.26 ENST00000409870.1
chromosome 2 open reading frame 88
chr11_-_102798148 0.26 ENST00000315274.7
matrix metallopeptidase 1
chr12_+_8822610 0.25 ENST00000299698.12
alpha-2-macroglobulin like 1
chr8_-_17697654 0.24 ENST00000297488.10
microtubule associated scaffold protein 1
chr12_-_84911178 0.24 ENST00000681688.1
solute carrier family 6 member 15
chr4_-_99321362 0.23 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chr3_+_57060658 0.23 ENST00000334325.2
spermatogenesis associated 12
chrX_-_32155462 0.23 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr12_-_122716790 0.23 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr19_-_49061997 0.22 ENST00000593537.1
neurotrophin 4
chr4_+_94974984 0.22 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr19_-_38253238 0.22 ENST00000587515.5
protein phosphatase 1 regulatory inhibitor subunit 14A
chr2_+_190137760 0.21 ENST00000396974.2
chromosome 2 open reading frame 88
chr19_-_51001668 0.21 ENST00000347619.8
ENST00000291726.11
ENST00000320838.9
kallikrein related peptidase 8
chr15_-_43879835 0.21 ENST00000636859.1
FERM domain containing 5
chr4_+_112818032 0.21 ENST00000672356.1
ENST00000672955.1
ankyrin 2
chr4_-_83114715 0.21 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
placenta associated 8
chr4_+_112818088 0.21 ENST00000673044.1
ENST00000672696.1
ENST00000672315.1
ENST00000672088.1
ENST00000671793.1
ENST00000672402.1
ENST00000671825.1
ENST00000672312.1
ENST00000672830.1
ENST00000672731.1
ENST00000671854.1
ENST00000672350.1
ENST00000672684.1
ENST00000672934.1
ENST00000673546.1
ENST00000673573.1
ENST00000503423.6
ENST00000673255.1
ENST00000671893.1
ENST00000672246.1
ENST00000672930.1
ENST00000673334.1
ENST00000673453.1
ENST00000673555.1
ENST00000672880.1
ENST00000672990.1
ENST00000673430.1
ENST00000673298.1
ENST00000672068.1
ENST00000672362.1
ENST00000672793.1
ENST00000672209.1
ENST00000671756.1
ENST00000671809.1
ENST00000671906.1
ENST00000672090.1
ENST00000672177.1
ENST00000672759.1
ENST00000672965.1
ENST00000673109.1
ENST00000503271.5
ENST00000506722.5
ENST00000673536.1
ENST00000672986.1
ankyrin 2
chr6_-_11779606 0.20 ENST00000506810.1
androgen dependent TFPI regulating protein
chr18_+_58362467 0.20 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr16_-_1981463 0.19 ENST00000356120.9
ENST00000354249.8
NADPH oxidase organizer 1
chr12_-_122703346 0.19 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr22_-_37188281 0.18 ENST00000397110.6
C1q and TNF related 6
chr4_+_88378842 0.18 ENST00000264346.12
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr4_-_46909206 0.17 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr4_+_112860981 0.17 ENST00000671704.1
ankyrin 2
chr17_-_82840010 0.17 ENST00000269394.4
ENST00000572562.1
zinc finger protein 750
chr3_+_98763331 0.16 ENST00000485391.5
ENST00000492254.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chrX_+_41688967 0.16 ENST00000378142.9
G protein-coupled receptor 34
chr4_+_112861053 0.16 ENST00000672221.1
ankyrin 2
chrX_+_41689006 0.16 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr6_-_26216673 0.15 ENST00000541790.3
H2B clustered histone 8
chr18_-_77127935 0.15 ENST00000581878.5
myelin basic protein
chr20_+_33662310 0.14 ENST00000375222.4
chromosome 20 open reading frame 144
chr3_-_36945042 0.14 ENST00000645898.2
ENST00000429976.5
tetratricopeptide repeat and ankyrin repeat containing 1
chr19_+_33374312 0.14 ENST00000585933.2
CCAAT enhancer binding protein gamma
chr7_+_97117676 0.14 ENST00000432641.3
succinate dehydrogenase complex assembly factor 3
chr16_-_66918839 0.13 ENST00000565235.2
ENST00000568632.5
ENST00000565796.5
cadherin 16
chr16_-_66918876 0.12 ENST00000570262.5
ENST00000299752.9
ENST00000394055.7
cadherin 16
chr9_+_128203371 0.12 ENST00000475805.5
ENST00000372923.8
ENST00000341179.11
ENST00000393594.7
dynamin 1
chr1_+_196819731 0.12 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr14_-_67412112 0.12 ENST00000216446.9
pleckstrin 2
chr19_+_49581304 0.12 ENST00000246794.10
proline rich and Gla domain 2
chr4_-_99290975 0.12 ENST00000209668.3
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr4_-_46909235 0.11 ENST00000505102.1
ENST00000355591.8
cytochrome c oxidase subunit 7B2
chr7_-_16465728 0.11 ENST00000307068.5
sclerostin domain containing 1
chr17_-_67996428 0.11 ENST00000580729.3
chromosome 17 open reading frame 58
chr12_+_19205294 0.11 ENST00000424268.5
pleckstrin homology domain containing A5
chr1_+_43337803 0.11 ENST00000372470.9
ENST00000413998.7
MPL proto-oncogene, thrombopoietin receptor
chr8_-_92017637 0.10 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr13_-_46182136 0.10 ENST00000323076.7
lymphocyte cytosolic protein 1
chr8_+_27633863 0.10 ENST00000337221.8
scavenger receptor class A member 3
chr11_+_61248122 0.10 ENST00000451616.6
pepsinogen A5
chrX_+_115561162 0.10 ENST00000355899.8
ENST00000626746.2
ENST00000289290.7
plastin 3
chr13_-_44161257 0.10 ENST00000400419.2
small integral membrane protein 2
chr8_+_144477975 0.10 ENST00000435887.2
protein phosphatase 1 regulatory subunit 16A
chr14_+_39233908 0.10 ENST00000280082.4
MIA SH3 domain ER export factor 2
chr9_+_122614738 0.10 ENST00000297913.3
olfactory receptor family 1 subfamily Q member 1
chr15_-_99251207 0.10 ENST00000394129.6
ENST00000558663.5
ENST00000394135.7
ENST00000561365.5
ENST00000560279.5
tetratricopeptide repeat domain 23
chr11_+_6205549 0.10 ENST00000316375.3
chromosome 11 open reading frame 42
chrX_-_21758097 0.10 ENST00000379494.4
small muscle protein X-linked
chr22_+_38057371 0.10 ENST00000437453.5
ENST00000356976.8
protein interacting with PRKCA 1
chr6_+_143864458 0.10 ENST00000237275.9
zinc finger C2HC-type containing 1B
chr1_+_65147657 0.10 ENST00000546702.5
adenylate kinase 4
chr3_-_171809770 0.10 ENST00000331659.2
phospholipase D1
chr17_-_68601357 0.10 ENST00000592554.2
FAM20A golgi associated secretory pathway pseudokinase
chr22_-_37188233 0.10 ENST00000434784.1
ENST00000337843.7
C1q and TNF related 6
chr8_+_32721823 0.10 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chr6_-_33317728 0.09 ENST00000431845.3
zinc finger and BTB domain containing 22
chr19_-_3478478 0.09 ENST00000591708.1
small integral membrane protein 24
chr1_+_202462730 0.09 ENST00000290419.9
ENST00000491336.5
protein phosphatase 1 regulatory subunit 12B
chr19_-_45076465 0.09 ENST00000303809.7
zinc finger protein 296
chr7_-_111562455 0.09 ENST00000452895.5
ENST00000405709.7
ENST00000452753.1
ENST00000331762.7
inner mitochondrial membrane peptidase subunit 2
chr16_+_3135121 0.09 ENST00000576416.5
ENST00000416391.6
zinc finger protein 213
chr1_-_216723437 0.09 ENST00000459955.5
ENST00000366937.5
ENST00000391890.7
estrogen related receptor gamma
chr6_-_32763466 0.08 ENST00000427449.1
ENST00000411527.5
major histocompatibility complex, class II, DQ beta 2
chrX_+_131083706 0.08 ENST00000370921.1
Rho GTPase activating protein 36
chr1_-_216723410 0.08 ENST00000469486.5
ENST00000481543.1
ENST00000408911.8
estrogen related receptor gamma
chr8_-_123737378 0.08 ENST00000419625.6
ENST00000262219.10
annexin A13
chr1_+_65147514 0.08 ENST00000545314.5
adenylate kinase 4
chr17_+_28335571 0.08 ENST00000544907.6
TNF alpha induced protein 1
chr1_+_156591741 0.08 ENST00000368234.7
ENST00000680087.1
ENST00000681734.1
ENST00000679369.1
ENST00000680269.1
ENST00000680661.1
ENST00000681054.1
ENST00000680004.1
ENST00000679702.1
ENST00000368235.8
ENST00000368233.3
NAD(P)HX epimerase
chr16_+_3134923 0.08 ENST00000574902.5
ENST00000396878.8
zinc finger protein 213
chr13_-_51845169 0.08 ENST00000627246.3
ENST00000629372.3
transmembrane protein 272
chr22_+_32043253 0.08 ENST00000266088.9
solute carrier family 5 member 1
chr8_-_108443409 0.08 ENST00000678023.1
ENST00000679198.1
ENST00000678881.1
ENST00000677084.1
ENST00000676663.1
ENST00000677614.1
ENST00000677040.1
ENST00000676487.1
ENST00000677409.1
ENST00000678797.1
ENST00000678334.1
eukaryotic translation initiation factor 3 subunit E
chr1_-_205422050 0.08 ENST00000367153.9
LEM domain containing 1
chr17_-_40867200 0.08 ENST00000647902.1
ENST00000251643.5
keratin 12
chr1_-_44788168 0.08 ENST00000372207.4
bestrophin 4
chr2_-_96208815 0.08 ENST00000443962.1
ENST00000337288.10
StAR related lipid transfer domain containing 7
chr7_+_97117718 0.07 ENST00000360382.4
succinate dehydrogenase complex assembly factor 3
chr19_+_53258292 0.07 ENST00000341702.3
vomeronasal 1 receptor 2
chr2_-_171434763 0.07 ENST00000442778.5
ENST00000453846.5
ENST00000612742.5
methyltransferase like 8
chr11_+_94543894 0.07 ENST00000358752.4
fucosyltransferase 4
chr10_+_97572771 0.07 ENST00000370655.6
ENST00000455090.1
ankyrin repeat domain 2
chr4_+_143381939 0.07 ENST00000505913.5
GRB2 associated binding protein 1
chr12_+_101594849 0.07 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr19_+_32691783 0.07 ENST00000397061.4
nudix hydrolase 19
chr19_+_55676621 0.07 ENST00000411543.6
epsin 1
chr18_-_66604076 0.07 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
cadherin 19
chr10_+_97572493 0.07 ENST00000307518.9
ENST00000298808.9
ankyrin repeat domain 2
chr20_-_4815100 0.07 ENST00000379376.2
Ras association domain family member 2
chr1_+_196943738 0.07 ENST00000367415.8
ENST00000367421.5
ENST00000649283.1
ENST00000476712.6
ENST00000496448.6
ENST00000473386.1
ENST00000649960.1
complement factor H related 2
chr1_-_202144677 0.07 ENST00000272217.7
ENST00000614750.1
ADP ribosylation factor like GTPase 8A
chr2_+_233681877 0.07 ENST00000373426.4
UDP glucuronosyltransferase family 1 member A7
chr17_+_28335718 0.07 ENST00000226225.7
TNF alpha induced protein 1
chr17_-_8152380 0.06 ENST00000317276.9
period circadian regulator 1
chr13_+_30932638 0.06 ENST00000380473.8
testis expressed 26
chr16_-_90019821 0.06 ENST00000568838.2
dysbindin domain containing 1
chr9_-_39239174 0.06 ENST00000358144.6
contactin associated protein family member 3
chr22_+_38057200 0.06 ENST00000404072.7
ENST00000424694.5
protein interacting with PRKCA 1
chr6_+_143677935 0.06 ENST00000440869.6
ENST00000367582.7
ENST00000451827.6
phosphatase and actin regulator 2
chr12_-_49897056 0.06 ENST00000552863.5
Fas apoptotic inhibitory molecule 2
chr15_-_33194696 0.06 ENST00000320930.7
ENST00000616417.5
formin 1
chr8_-_48921419 0.06 ENST00000020945.4
snail family transcriptional repressor 2
chr13_-_49444004 0.06 ENST00000410043.5
ENST00000409308.6
calcium binding protein 39 like
chr6_+_69232406 0.06 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr19_+_17511606 0.06 ENST00000252603.7
ENST00000600923.5
6-phosphogluconolactonase
chr2_+_102187015 0.06 ENST00000441515.3
ENST00000264257.7
interleukin 1 receptor like 2
chr3_+_113838772 0.06 ENST00000358160.9
GRAM domain containing 1C
chr19_-_18941184 0.06 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr6_+_32154010 0.06 ENST00000375137.6
palmitoyl-protein thioesterase 2
chr13_+_31739520 0.06 ENST00000298386.7
relaxin family peptide receptor 2
chr7_-_80919017 0.05 ENST00000265361.8
semaphorin 3C
chr19_-_50476838 0.05 ENST00000600100.6
family with sequence similarity 71 member E1
chr19_+_39125769 0.05 ENST00000602004.1
ENST00000599470.5
ENST00000321944.8
ENST00000593480.5
ENST00000358301.7
ENST00000593690.5
ENST00000599386.5
p21 (RAC1) activated kinase 4
chr1_+_202348727 0.05 ENST00000356764.6
protein phosphatase 1 regulatory subunit 12B
chr1_-_248825906 0.05 ENST00000366472.6
SH3 binding domain protein 5 like
chr10_+_43606415 0.05 ENST00000430885.5
ENST00000374435.3
ENST00000361807.8
zinc finger protein 485
chr6_-_70283105 0.05 ENST00000683980.1
collagen type IX alpha 1 chain
chr19_-_45076504 0.05 ENST00000622376.1
zinc finger protein 296
chr1_-_165355746 0.05 ENST00000367893.4
LIM homeobox transcription factor 1 alpha
chr12_-_52796110 0.05 ENST00000417996.2
keratin 3
chr3_+_23810436 0.05 ENST00000467766.5
ENST00000424381.5
ubiquitin conjugating enzyme E2 E1
chr13_+_31739542 0.05 ENST00000380314.2
relaxin family peptide receptor 2
chr3_-_101320558 0.05 ENST00000193391.8
interphotoreceptor matrix proteoglycan 2
chr11_-_75306688 0.05 ENST00000532525.1
arrestin beta 1
chr8_-_139654330 0.05 ENST00000647605.1
potassium two pore domain channel subfamily K member 9
chr16_-_58629816 0.05 ENST00000564557.1
ENST00000317147.10
ENST00000569240.5
ENST00000441024.6
CCR4-NOT transcription complex subunit 1
chr10_-_75109085 0.05 ENST00000607131.5
dual specificity phosphatase 13
chr15_+_63529142 0.05 ENST00000268049.11
ubiquitin specific peptidase 3
chr7_-_1569955 0.05 ENST00000288607.3
ENST00000404674.7
proteasome assembly chaperone 3
chr6_+_32153441 0.05 ENST00000414204.5
ENST00000361568.6
ENST00000395523.5
palmitoyl-protein thioesterase 2
chr3_+_25790076 0.05 ENST00000280701.8
ENST00000420173.2
3-oxoacyl-ACP synthase, mitochondrial
chr11_+_31650024 0.05 ENST00000638317.1
elongator acetyltransferase complex subunit 4
chr19_+_35651245 0.05 ENST00000590618.1
cytochrome c oxidase subunit 6B1
chr5_+_50665899 0.05 ENST00000505697.6
poly(ADP-ribose) polymerase family member 8
chr1_-_156490599 0.05 ENST00000360595.7
myocyte enhancer factor 2D
chr8_+_103298433 0.05 ENST00000522566.5
frizzled class receptor 6
chr10_-_75109172 0.05 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
dual specificity phosphatase 13
chr1_+_46341164 0.05 ENST00000537428.2
NOP2/Sun RNA methyltransferase 4
chr12_+_10307950 0.05 ENST00000543420.5
ENST00000543777.5
killer cell lectin like receptor D1
chr12_+_123233420 0.05 ENST00000253233.6
ENST00000366329.7
ENST00000546132.2
ENST00000536130.2
chromosome 12 open reading frame 65
chr10_-_72217126 0.05 ENST00000317126.8
activating signal cointegrator 1 complex subunit 1
chr11_+_71833200 0.05 ENST00000328698.2
defensin beta 108B
chr8_+_132775340 0.05 ENST00000622263.4
ENST00000220847.8
ENST00000395379.5
ENST00000395386.7
ENST00000485595.5
ENST00000337920.8
PHD finger protein 20 like 1
chr6_-_70283214 0.05 ENST00000683758.1
collagen type IX alpha 1 chain
chr10_+_114938187 0.05 ENST00000298746.5
TruB pseudouridine synthase family member 1
chr2_+_200889327 0.04 ENST00000426253.5
ENST00000454952.1
ENST00000651500.1
ENST00000409020.6
ENST00000359683.8
NGG1 interacting factor 3 like 1
chr6_-_70283184 0.04 ENST00000320755.12
collagen type IX alpha 1 chain
chr6_-_137219028 0.04 ENST00000647124.1
ENST00000642390.1
ENST00000645753.1
ENST00000646036.1
ENST00000646898.1
ENST00000644894.1
interferon gamma receptor 1
chr19_+_17511835 0.04 ENST00000595782.1
6-phosphogluconolactonase
chr1_+_206897435 0.04 ENST00000391929.7
ENST00000294984.7
ENST00000611909.4
ENST00000367093.3
interleukin 24
chr3_+_49021071 0.04 ENST00000395458.6
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr16_+_56935371 0.04 ENST00000568358.1
homocysteine inducible ER protein with ubiquitin like domain 1
chr7_+_117611617 0.04 ENST00000468795.1
CF transmembrane conductance regulator
chr11_+_35189869 0.04 ENST00000525688.5
ENST00000278385.10
ENST00000533222.5
CD44 molecule (Indian blood group)
chr8_-_20183090 0.04 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr8_-_20183127 0.04 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr14_+_35826298 0.04 ENST00000216807.12
BRMS1 like transcriptional repressor
chr9_+_136952256 0.04 ENST00000371633.8
lipocalin 12
chr18_-_27185284 0.04 ENST00000580774.2
ENST00000618847.5
carbohydrate sulfotransferase 9
chr1_+_46340780 0.04 ENST00000474844.6
NOP2/Sun RNA methyltransferase 4
chr2_-_180007254 0.04 ENST00000410053.8
CWC22 spliceosome associated protein homolog
chr5_-_176416222 0.04 ENST00000508425.5
clathrin light chain B
chr6_+_167999092 0.04 ENST00000443060.6
kinesin family member 25
chr19_-_50637939 0.04 ENST00000338916.8
synaptotagmin 3
chr6_-_26271815 0.04 ENST00000614378.1
H3 clustered histone 8
chr12_+_12813316 0.04 ENST00000352940.8
ENST00000358007.7
ENST00000544400.1
DEAD-box helicase 47
chr1_-_200409976 0.04 ENST00000367352.3
zinc finger protein 281
chr4_+_75514455 0.04 ENST00000508105.5
ENST00000311638.7
ENST00000380837.7
ENST00000507556.5
ENST00000504190.5
ENST00000507885.5
ENST00000502620.1
ENST00000514480.1
THAP domain containing 6
chrX_-_107118783 0.04 ENST00000372487.5
ENST00000372479.7
RNA binding motif protein 41

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.2 GO:0048867 stem cell fate determination(GO:0048867)
0.1 0.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.0 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.2 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.5 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.5 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.2 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.2 GO:0015820 leucine transport(GO:0015820)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.0 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.0 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.0 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 1.0 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.1 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.0 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.0 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)