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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NKX2-8

Z-value: 0.24

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Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
ENSG00000136327.7 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg38_v1_chr14_-_36582593_365826260.521.9e-01Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_3691887 0.09 ENST00000552050.5
purinergic receptor P2X 5
chr1_+_152985231 0.08 ENST00000368762.1
small proline rich protein 1A
chr18_-_58629084 0.08 ENST00000361673.4
alpha kinase 2
chrX_+_153687918 0.08 ENST00000253122.10
solute carrier family 6 member 8
chr11_-_5441514 0.08 ENST00000380211.1
olfactory receptor family 51 subfamily I member 1
chr12_-_85836372 0.07 ENST00000361228.5
Ras association domain family member 9
chr6_+_125203639 0.07 ENST00000392482.6
TPD52 like 1
chr12_+_25052634 0.06 ENST00000548766.5
inositol 1,4,5-triphosphate receptor associated 2
chr12_+_25052512 0.06 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
inositol 1,4,5-triphosphate receptor associated 2
chr15_+_45129933 0.05 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
dual oxidase 1
chr9_-_21385395 0.05 ENST00000380206.4
interferon alpha 2
chr11_-_72642450 0.05 ENST00000444035.6
ENST00000544570.5
phosphodiesterase 2A
chr3_+_111998915 0.05 ENST00000478951.6
transgelin 3
chr14_-_23155302 0.05 ENST00000529705.6
solute carrier family 7 member 8
chr11_-_72642407 0.05 ENST00000376450.7
phosphodiesterase 2A
chr3_+_111998739 0.05 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr8_-_143568854 0.04 ENST00000524906.5
ENST00000532862.1
ENST00000534459.5
maestro heat like repeat family member 6
chr19_+_45340736 0.04 ENST00000391946.7
kinesin light chain 3
chr12_+_25052732 0.04 ENST00000547044.5
inositol 1,4,5-triphosphate receptor associated 2
chr19_-_50833187 0.04 ENST00000598673.1
kallikrein related peptidase 15
chr17_-_69150062 0.04 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr10_+_24466487 0.04 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr5_+_81233314 0.04 ENST00000511719.5
ENST00000437669.5
ENST00000254035.9
ENST00000424301.6
ENST00000505060.1
creatine kinase, mitochondrial 2
chr12_-_84892120 0.04 ENST00000680379.1
solute carrier family 6 member 15
chr16_+_176659 0.04 ENST00000320868.9
ENST00000397797.1
hemoglobin subunit alpha 1
chr13_-_46182136 0.04 ENST00000323076.7
lymphocyte cytosolic protein 1
chr1_+_172420681 0.03 ENST00000367727.9
chromosome 1 open reading frame 105
chr8_+_124539097 0.03 ENST00000606244.2
ENST00000276689.8
ENST00000518008.5
ENST00000517367.1
NADH:ubiquinone oxidoreductase subunit B9
chr16_-_66918839 0.03 ENST00000565235.2
ENST00000568632.5
ENST00000565796.5
cadherin 16
chr11_+_18132565 0.03 ENST00000621697.2
MAS related GPR family member X3
chr16_-_66918876 0.03 ENST00000570262.5
ENST00000299752.9
ENST00000394055.7
cadherin 16
chr5_-_79512794 0.03 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
homer scaffold protein 1
chr9_-_94640248 0.03 ENST00000415431.5
fructose-bisphosphatase 1
chr13_-_51845169 0.03 ENST00000627246.3
ENST00000629372.3
transmembrane protein 272
chr4_-_99564026 0.03 ENST00000394876.7
tRNA methyltransferase 10A
chr1_+_54998927 0.03 ENST00000651561.1
barttin CLCNK type accessory subunit beta
chr4_-_99563984 0.03 ENST00000394877.7
tRNA methyltransferase 10A
chr11_-_114595750 0.03 ENST00000424261.6
neurexophilin and PC-esterase domain family member 4
chr14_+_63761836 0.03 ENST00000674003.1
spectrin repeat containing nuclear envelope protein 2
chr4_+_70334963 0.03 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr6_+_125986434 0.03 ENST00000368332.7
tRNA methyltransferase 11 homolog
chr2_+_86441341 0.03 ENST00000312912.10
ENST00000409064.5
lysine demethylase 3A
chr8_-_65842051 0.02 ENST00000401827.8
phosphodiesterase 7A
chr7_+_112423137 0.02 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chr4_-_152679984 0.02 ENST00000304385.8
ENST00000504064.1
transmembrane protein 154
chr10_+_72893734 0.02 ENST00000334011.10
oncoprotein induced transcript 3
chr3_+_66998297 0.02 ENST00000484414.5
ENST00000460576.5
ENST00000417314.2
kelch repeat and BTB domain containing 8
chr2_-_29074515 0.02 ENST00000331664.6
photoreceptor cilium actin regulator
chr12_-_8066331 0.02 ENST00000546241.1
ENST00000307637.5
complement C3a receptor 1
chr14_-_24263162 0.02 ENST00000206765.11
ENST00000544573.5
transglutaminase 1
chr16_+_172869 0.02 ENST00000251595.11
ENST00000397806.1
ENST00000484216.1
hemoglobin subunit alpha 2
chr2_+_109614328 0.02 ENST00000356454.5
sosondowah ankyrin repeat domain family member C
chr12_-_14938508 0.02 ENST00000266397.7
endoplasmic reticulum protein 27
chr6_+_116461364 0.02 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr8_+_97887903 0.02 ENST00000520016.5
matrilin 2
chr6_+_34466059 0.02 ENST00000620693.4
ENST00000244458.7
ENST00000374043.6
protein kinase C and casein kinase substrate in neurons 1
chr1_-_155991198 0.02 ENST00000673475.1
Rho/Rac guanine nucleotide exchange factor 2
chrX_+_41688967 0.02 ENST00000378142.9
G protein-coupled receptor 34
chr18_+_46917561 0.02 ENST00000683218.1
katanin catalytic subunit A1 like 2
chrX_+_41689006 0.02 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr1_-_155033778 0.02 ENST00000368424.4
DC-STAMP domain containing 2
chr11_+_5389377 0.02 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chrX_-_31178220 0.02 ENST00000681026.1
dystrophin
chr4_-_99563668 0.02 ENST00000273962.7
tRNA methyltransferase 10A
chrX_-_31178149 0.02 ENST00000679437.1
dystrophin
chrX_+_119399286 0.02 ENST00000217909.8
solute carrier family 25 member 43
chr12_-_64390727 0.02 ENST00000543942.7
chromosome 12 open reading frame 56
chrX_-_32155462 0.02 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr16_+_29663219 0.02 ENST00000436527.5
ENST00000360121.4
ENST00000652691.1
ENST00000449759.2
sialophorin
quinolinate phosphoribosyltransferase
chr12_-_64390691 0.02 ENST00000333722.9
chromosome 12 open reading frame 56
chr3_+_52779916 0.02 ENST00000537050.5
inter-alpha-trypsin inhibitor heavy chain 1
chr14_+_21030509 0.02 ENST00000481535.5
tubulin polymerization promoting protein family member 2
chr9_-_21202205 0.02 ENST00000239347.3
interferon alpha 7
chr9_-_21166660 0.02 ENST00000380225.1
interferon alpha 21
chr22_+_32357867 0.02 ENST00000249007.4
ret finger protein like 3
chr14_+_37198025 0.02 ENST00000556451.5
ENST00000556753.5
mirror-image polydactyly 1
chr3_-_122022122 0.02 ENST00000393631.5
ENST00000273691.7
ENST00000344209.10
immunoglobulin like domain containing receptor 1
chr7_-_5959083 0.02 ENST00000539903.5
radial spoke head 10 homolog B
chr22_+_22343185 0.02 ENST00000427632.2
immunoglobulin lambda variable 9-49
chr6_-_32763466 0.02 ENST00000427449.1
ENST00000411527.5
major histocompatibility complex, class II, DQ beta 2
chr7_-_95396349 0.02 ENST00000427422.5
ENST00000451904.5
ENST00000265627.10
paraoxonase 3
chr3_-_52454032 0.02 ENST00000232975.8
troponin C1, slow skeletal and cardiac type
chr8_-_124539037 0.02 ENST00000519232.5
ENST00000523888.5
ENST00000522810.5
ENST00000519548.5
ENST00000517678.5
ENST00000605953.5
ENST00000276692.11
ENST00000630259.1
TatD DNase domain containing 1
chr22_+_19131271 0.02 ENST00000399635.4
testis specific serine kinase 2
chr17_-_7208325 0.02 ENST00000650120.1
ENST00000648760.1
discs large MAGUK scaffold protein 4
chr14_+_21887848 0.02 ENST00000390437.2
T cell receptor alpha variable 12-2
chr8_-_123396412 0.02 ENST00000287394.10
ATPase family AAA domain containing 2
chr8_+_103298836 0.01 ENST00000523739.5
ENST00000358755.5
frizzled class receptor 6
chr19_+_51127030 0.01 ENST00000599948.1
sialic acid binding Ig like lectin 9
chr12_-_75209814 0.01 ENST00000549446.6
potassium voltage-gated channel subfamily C member 2
chrX_-_27463341 0.01 ENST00000412172.4
protein phosphatase 4 regulatory subunit 3C
chr17_-_7204502 0.01 ENST00000486626.8
ENST00000648263.1
discs large MAGUK scaffold protein 4
chr8_-_140800535 0.01 ENST00000521986.5
ENST00000523539.5
protein tyrosine kinase 2
chr13_-_46390042 0.01 ENST00000389908.7
rubicon like autophagy enhancer
chr22_+_38057200 0.01 ENST00000404072.7
ENST00000424694.5
protein interacting with PRKCA 1
chr5_-_176629943 0.01 ENST00000510387.5
ENST00000506696.1
synuclein beta
chr20_+_64164446 0.01 ENST00000328439.6
myelin transcription factor 1
chr13_+_75549477 0.01 ENST00000618773.4
ubiquitin C-terminal hydrolase L3
chr3_-_53130405 0.01 ENST00000467048.1
ENST00000296292.8
ENST00000394738.7
RFT1 homolog
chr4_+_75556048 0.01 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
odontogenesis associated phosphoprotein
chr20_+_43514492 0.01 ENST00000373135.8
ENST00000373134.5
L3MBTL histone methyl-lysine binding protein 1
chr17_+_78231310 0.01 ENST00000374946.7
ENST00000421688.5
ENST00000586400.5
transmembrane protein 235
chr1_+_37807762 0.01 ENST00000373042.5
chromosome 1 open reading frame 122
chr14_+_103123452 0.01 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr12_+_65169546 0.01 ENST00000308330.3
LEM domain containing 3
chr4_+_71062642 0.01 ENST00000649996.1
solute carrier family 4 member 4
chr1_+_16022030 0.01 ENST00000331433.5
chloride voltage-gated channel Ka
chr6_-_32666648 0.01 ENST00000399082.7
ENST00000399079.7
ENST00000374943.8
ENST00000434651.6
major histocompatibility complex, class II, DQ beta 1
chr18_-_27143024 0.01 ENST00000581714.5
carbohydrate sulfotransferase 9
chr4_+_143381939 0.01 ENST00000505913.5
GRB2 associated binding protein 1
chr6_+_69232406 0.01 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr12_-_6493718 0.01 ENST00000543959.5
ENST00000543164.5
ENST00000543703.1
ENST00000537701.5
mitochondrial ribosomal protein L51
chr10_+_116545907 0.01 ENST00000369221.2
pancreatic lipase
chr14_-_58427158 0.01 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
translocase of inner mitochondrial membrane 9
chr17_-_9905248 0.01 ENST00000226193.6
recoverin
chr9_+_21409116 0.01 ENST00000380205.2
interferon alpha 8
chr7_+_75398915 0.01 ENST00000437796.1
tripartite motif containing 73
chr12_-_117968972 0.01 ENST00000339824.7
kinase suppressor of ras 2
chr15_-_34754989 0.01 ENST00000290374.5
gap junction protein delta 2
chr14_-_77616630 0.01 ENST00000216484.7
serine palmitoyltransferase long chain base subunit 2
chrX_-_70260199 0.01 ENST00000374519.4
pyrimidinergic receptor P2Y4
chr7_-_157010615 0.01 ENST00000252971.11
motor neuron and pancreas homeobox 1
chr15_-_51243011 0.01 ENST00000405913.7
ENST00000559878.5
cytochrome P450 family 19 subfamily A member 1
chr14_+_24070837 0.01 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
copine 6
chr3_-_39051935 0.01 ENST00000668754.1
ENST00000302328.9
sodium voltage-gated channel alpha subunit 11
chr2_+_232633551 0.01 ENST00000264059.8
EF-hand domain family member D1
chr22_-_36817510 0.01 ENST00000443735.1
parvalbumin
chr3_-_180679468 0.01 ENST00000651046.1
ENST00000476379.6
coiled-coil domain containing 39
chr19_+_43533384 0.01 ENST00000601282.1
zinc finger protein 575
chr3_-_196515315 0.01 ENST00000397537.3
single-pass membrane protein with coiled-coil domains 1
chr6_-_70303070 0.01 ENST00000370496.3
ENST00000357250.11
collagen type IX alpha 1 chain
chr16_-_68015911 0.01 ENST00000574912.1
DPEP2 neighbor
chr12_+_56996151 0.01 ENST00000556850.1
G protein-coupled receptor 182
chrX_-_72875974 0.01 ENST00000595412.5
DMRT like family C1
chr2_+_135531460 0.01 ENST00000683871.1
ENST00000409478.5
ENST00000264160.8
ENST00000438014.5
R3H domain containing 1
chr1_-_93681829 0.01 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr21_+_32298945 0.01 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr20_+_63738270 0.01 ENST00000467211.1
novel transcript, LIME1-SLC2A4RG readthrough
chr12_+_121400102 0.01 ENST00000392465.7
ENST00000554606.5
ENST00000392464.3
ENST00000555076.1
ring finger protein 34
chr1_-_11055820 0.01 ENST00000490101.1
spermidine synthase
chr17_-_44911281 0.01 ENST00000638304.1
ENST00000591880.2
ENST00000586125.2
ENST00000639921.1
glial fibrillary acidic protein
chr3_+_186666003 0.01 ENST00000232003.5
histidine rich glycoprotein
chr5_+_141094595 0.01 ENST00000622947.1
ENST00000194155.7
ENST00000624874.1
ENST00000625033.1
protocadherin beta 2
chr12_-_6493295 0.01 ENST00000540949.1
mitochondrial ribosomal protein L51
chr12_-_49110840 0.01 ENST00000550137.5
ENST00000267102.13
ENST00000547382.5
limb development membrane protein 1 like
chr22_+_17638584 0.01 ENST00000337612.9
ENST00000418951.6
ENST00000538149.5
ENST00000543133.5
ENST00000611738.4
ENST00000616863.4
ENST00000618481.4
ENST00000317582.10
ENST00000493680.5
BCL2 like 13
chr7_+_151232464 0.01 ENST00000482173.5
ENST00000495645.5
ENST00000035307.6
chondroitin polymerizing factor 2
chr4_+_6693870 0.01 ENST00000296370.4
S100 calcium binding protein P
chr3_+_173584433 0.01 ENST00000361589.8
neuroligin 1
chr4_-_122456725 0.01 ENST00000226730.5
interleukin 2
chr2_+_118942188 0.01 ENST00000327097.5
macrophage receptor with collagenous structure
chr14_-_105856183 0.01 ENST00000637539.2
ENST00000390559.6
immunoglobulin heavy constant mu
chr12_-_24562438 0.01 ENST00000646273.1
ENST00000659413.1
ENST00000446891.7
SRY-box transcription factor 5
chr20_+_58689124 0.01 ENST00000525967.5
ENST00000525817.5
aminopeptidase like 1
chr8_+_42338477 0.01 ENST00000518925.5
ENST00000265421.9
DNA polymerase beta
chr9_+_93289187 0.01 ENST00000453718.2
WNK lysine deficient protein kinase 2
chrX_+_116436599 0.01 ENST00000598581.3
solute carrier family 6 member 14
chr11_-_10693504 0.01 ENST00000529547.1
ENST00000558540.5
inositol 1,4,5-triphosphate receptor associated 1
chr8_+_39934955 0.01 ENST00000502986.2
indoleamine 2,3-dioxygenase 2
chr11_+_121129964 0.01 ENST00000645008.1
tectorin alpha
chr14_-_106211453 0.01 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr1_-_94541636 0.01 ENST00000370207.4
coagulation factor III, tissue factor
chr14_-_106538331 0.01 ENST00000390624.3
immunoglobulin heavy variable 3-48
chr11_-_10693570 0.01 ENST00000527509.7
inositol 1,4,5-triphosphate receptor associated 1
chr2_-_158456702 0.01 ENST00000409889.1
ENST00000283233.10
coiled-coil domain containing 148
chr12_+_51048318 0.01 ENST00000550929.5
ENST00000550442.5
ENST00000549340.5
ENST00000548209.5
ENST00000548251.5
ENST00000550814.5
ENST00000547660.5
ENST00000262055.9
ENST00000548401.1
ENST00000418425.6
ENST00000547008.5
ENST00000552739.5
LETM1 domain containing 1
chr6_+_147508645 0.01 ENST00000367474.2
sterile alpha motif domain containing 5
chr12_+_8992029 0.01 ENST00000543895.1
killer cell lectin like receptor G1
chr14_+_35046238 0.01 ENST00000280987.9
family with sequence similarity 177 member A1
chr1_+_151540299 0.01 ENST00000392712.7
ENST00000368848.6
ENST00000368849.8
ENST00000353024.4
tuftelin 1
chr3_-_52154382 0.01 ENST00000474012.1
ENST00000296484.7
POC1 centriolar protein A
chr16_+_48244331 0.01 ENST00000535754.5
lon peptidase 2, peroxisomal
chr1_+_75786246 0.01 ENST00000319942.8
Rab geranylgeranyltransferase subunit beta
chr1_+_32205657 0.00 ENST00000291358.11
ENST00000537469.2
IQ motif containing C
chr14_-_58427489 0.00 ENST00000555593.5
translocase of inner mitochondrial membrane 9
chr6_-_39322968 0.00 ENST00000507712.5
potassium two pore domain channel subfamily K member 16
chr3_-_134250831 0.00 ENST00000623711.4
receptor like tyrosine kinase
chr14_-_105626066 0.00 ENST00000641978.1
ENST00000390543.3
immunoglobulin heavy constant gamma 4 (G4m marker)
chr2_+_100974849 0.00 ENST00000450763.1
neuronal PAS domain protein 2
chr2_+_206159580 0.00 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
eukaryotic translation elongation factor 1 beta 2
chr11_+_75562056 0.00 ENST00000533603.5
serpin family H member 1
chr13_+_45464901 0.00 ENST00000349995.10
component of oligomeric golgi complex 3
chr19_-_33225844 0.00 ENST00000253188.8
solute carrier family 7 member 10
chr8_+_66429003 0.00 ENST00000320270.4
ribosome biogenesis regulator 1 homolog
chrX_+_123960519 0.00 ENST00000455404.5
ENST00000218089.13
stromal antigen 2
chr11_+_35189869 0.00 ENST00000525688.5
ENST00000278385.10
ENST00000533222.5
CD44 molecule (Indian blood group)
chr4_+_89894846 0.00 ENST00000264790.7
multimerin 1
chr6_-_55875583 0.00 ENST00000370830.4
bone morphogenetic protein 5
chr11_-_133845495 0.00 ENST00000299140.8
ENST00000532889.1
spermatogenesis associated 19
chr6_+_52186373 0.00 ENST00000648244.1
interleukin 17A
chr22_+_29438583 0.00 ENST00000354373.2
ret finger protein like 1
chr7_+_130207847 0.00 ENST00000297819.4
serine rich single-pass membrane protein 1
chr5_+_43602648 0.00 ENST00000505678.6
ENST00000512422.5
ENST00000264663.9
ENST00000670904.1
ENST00000653251.1
nicotinamide nucleotide transhydrogenase
chr7_-_36724543 0.00 ENST00000612871.4
acyloxyacyl hydrolase
chr8_-_144465648 0.00 ENST00000424149.6
ENST00000530637.1
cysteine and histidine rich 1
chr1_+_151060357 0.00 ENST00000368921.5
MLLT11 transcription factor 7 cofactor
chr8_+_66493556 0.00 ENST00000305454.8
ENST00000522977.5
ENST00000480005.1
vexin
chr4_+_177309866 0.00 ENST00000264596.4
nei like DNA glycosylase 3
chr8_+_66493514 0.00 ENST00000521495.5
vexin
chr17_+_48107549 0.00 ENST00000580219.5
ENST00000452859.6
ENST00000393405.6
sorting nexin 11

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)