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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 0.31

Motif logo

Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Gene Symbol Gene ID Gene Info
ENSG00000214513.4 notochord homeobox
ENSG00000119614.3 visual system homeobox 2
ENSG00000115844.11 distal-less homeobox 2
ENSG00000006377.11 distal-less homeobox 6
ENSG00000163623.10 NK6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX6-1hg38_v1_chr4_-_84499281_844992980.432.8e-01Click!
DLX2hg38_v1_chr2_-_172102893_1721029090.413.2e-01Click!
DLX6hg38_v1_chr7_+_97005538_97005562-0.127.8e-01Click!

Activity profile of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Sorted Z-values of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_27970273 0.56 ENST00000542963.1
ENST00000535992.5
parathyroid hormone like hormone
chr12_-_27970047 0.55 ENST00000395868.7
parathyroid hormone like hormone
chr5_+_67004618 0.53 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr3_+_111999189 0.35 ENST00000455401.6
transgelin 3
chr4_-_25863537 0.34 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr3_+_111998915 0.33 ENST00000478951.6
transgelin 3
chr3_-_151316795 0.32 ENST00000260843.5
G protein-coupled receptor 87
chr3_+_111998739 0.32 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr8_-_42377227 0.31 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr3_+_111999326 0.31 ENST00000494932.1
transgelin 3
chr5_-_1882902 0.29 ENST00000231357.7
iroquois homeobox 4
chr11_-_124320197 0.28 ENST00000624618.2
olfactory receptor family 8 subfamily D member 2
chr20_-_51802433 0.26 ENST00000395997.3
spalt like transcription factor 4
chr5_+_36606355 0.23 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
solute carrier family 1 member 3
chr1_+_160400543 0.22 ENST00000368061.3
VANGL planar cell polarity protein 2
chr4_-_73620391 0.22 ENST00000395777.6
ENST00000307439.10
Ras association domain family member 6
chr7_+_70596078 0.21 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr9_+_12693327 0.21 ENST00000388918.10
tyrosinase related protein 1
chr13_-_46142834 0.21 ENST00000674665.1
lymphocyte cytosolic protein 1
chr6_+_130018565 0.20 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr8_-_42501224 0.20 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr12_+_41437680 0.19 ENST00000649474.1
ENST00000539469.6
ENST00000298919.7
PDZ domain containing ring finger 4
chr4_+_76435216 0.19 ENST00000296043.7
shroom family member 3
chr2_-_70553638 0.18 ENST00000444975.5
ENST00000445399.5
ENST00000295400.11
ENST00000418333.6
transforming growth factor alpha
chr5_-_24644968 0.18 ENST00000264463.8
cadherin 10
chr4_+_40196907 0.18 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr10_+_24466487 0.17 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
chr20_-_51802509 0.17 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr6_-_39725335 0.17 ENST00000538893.5
kinesin family member 6
chr2_-_70553440 0.16 ENST00000450929.5
transforming growth factor alpha
chr13_-_85799400 0.16 ENST00000647374.2
SLIT and NTRK like family member 6
chr19_-_51019699 0.15 ENST00000358789.8
kallikrein related peptidase 10
chr7_-_25228485 0.15 ENST00000222674.2
neuropeptide VF precursor
chr6_-_136526472 0.15 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr19_-_51020154 0.15 ENST00000391805.5
ENST00000599077.1
kallikrein related peptidase 10
chr19_-_51020019 0.14 ENST00000309958.7
kallikrein related peptidase 10
chr18_+_63777773 0.14 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr4_+_40197023 0.13 ENST00000381799.10
ras homolog family member H
chr8_+_104223320 0.13 ENST00000339750.3
regulating synaptic membrane exocytosis 2
chr18_-_55422492 0.12 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr4_-_73620629 0.12 ENST00000342081.7
Ras association domain family member 6
chr13_-_35476682 0.12 ENST00000379919.6
mab-21 like 1
chr11_-_120138104 0.12 ENST00000341846.10
tripartite motif containing 29
chr8_-_108787563 0.12 ENST00000297459.4
transmembrane protein 74
chr14_+_61187544 0.12 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chr1_+_160190567 0.12 ENST00000368078.8
calsequestrin 1
chr5_+_148203024 0.12 ENST00000325630.3
serine peptidase inhibitor Kazal type 6
chr14_-_53956811 0.11 ENST00000559087.5
ENST00000245451.9
bone morphogenetic protein 4
chr4_+_68447453 0.11 ENST00000305363.9
transmembrane serine protease 11E
chr21_-_40847149 0.11 ENST00000400454.6
DS cell adhesion molecule
chr1_-_242449478 0.11 ENST00000427495.5
phospholipase D family member 5
chr17_-_66229380 0.11 ENST00000205948.11
apolipoprotein H
chr17_-_7263959 0.11 ENST00000571932.2
claudin 7
chr12_-_27972725 0.11 ENST00000545234.6
parathyroid hormone like hormone
chr11_-_129192198 0.11 ENST00000310343.13
Rho GTPase activating protein 32
chr11_+_65787056 0.10 ENST00000335987.8
ovo like transcriptional repressor 1
chr13_-_75366973 0.10 ENST00000648194.1
TBC1 domain family member 4
chr17_-_40755328 0.10 ENST00000312150.5
keratin 25
chrX_+_105948429 0.10 ENST00000540278.1
Nik related kinase
chr11_-_129192291 0.10 ENST00000682385.1
Rho GTPase activating protein 32
chrX_-_32412220 0.10 ENST00000619831.5
dystrophin
chr16_+_69105636 0.09 ENST00000569188.6
hyaluronan synthase 3
chr7_-_41703062 0.09 ENST00000242208.5
inhibin subunit beta A
chr4_+_112860981 0.09 ENST00000671704.1
ankyrin 2
chr8_-_20183127 0.09 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr12_-_70637405 0.09 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr4_+_112860912 0.09 ENST00000671951.1
ankyrin 2
chr4_+_112861053 0.09 ENST00000672221.1
ankyrin 2
chr12_-_27971970 0.09 ENST00000395872.5
ENST00000201015.8
parathyroid hormone like hormone
chr2_-_49974182 0.09 ENST00000412315.5
ENST00000378262.7
neurexin 1
chr8_-_20183090 0.09 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr11_-_16356538 0.09 ENST00000683767.1
SRY-box transcription factor 6
chr6_-_136466858 0.09 ENST00000544465.5
microtubule associated protein 7
chr8_+_104223344 0.09 ENST00000523362.5
regulating synaptic membrane exocytosis 2
chr17_-_40782544 0.09 ENST00000301656.4
keratin 27
chr17_-_40799939 0.08 ENST00000306658.8
keratin 28
chr11_-_115504389 0.08 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr13_+_108629605 0.08 ENST00000457511.7
myosin XVI
chr5_+_127649018 0.08 ENST00000379445.7
cortexin 3
chrX_-_134658450 0.08 ENST00000359237.9
placenta enriched 1
chr2_-_49974155 0.08 ENST00000635519.1
neurexin 1
chr11_-_117876719 0.08 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr10_+_116324440 0.08 ENST00000333254.4
coiled-coil domain containing 172
chr19_-_3557563 0.08 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr5_+_148202771 0.08 ENST00000514389.5
ENST00000621437.4
serine peptidase inhibitor Kazal type 6
chr12_+_80716906 0.08 ENST00000228644.4
myogenic factor 5
chr11_+_20599602 0.07 ENST00000525748.6
solute carrier family 6 member 5
chr12_+_28257195 0.07 ENST00000381259.5
coiled-coil domain containing 91
chr11_-_117876892 0.07 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr12_-_52434363 0.07 ENST00000252245.6
keratin 75
chr6_+_121437378 0.07 ENST00000650427.1
ENST00000647564.1
gap junction protein alpha 1
chr2_+_127645864 0.07 ENST00000544369.5
G protein-coupled receptor 17
chr17_-_10518536 0.07 ENST00000226207.6
myosin heavy chain 1
chr2_+_161416273 0.07 ENST00000389554.8
T-box brain transcription factor 1
chr12_-_89352487 0.07 ENST00000548755.1
ENST00000279488.8
dual specificity phosphatase 6
chr10_+_132397168 0.07 ENST00000631148.2
ENST00000305233.6
PWWP domain containing 2B
chr3_+_130850585 0.07 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr20_-_52105644 0.07 ENST00000371523.8
ZFP64 zinc finger protein
chr22_-_32464440 0.07 ENST00000397450.2
ENST00000397452.5
ENST00000300399.8
BPI fold containing family C
chr16_-_81220370 0.07 ENST00000337114.8
polycystin 1 like 2 (gene/pseudogene)
chr8_+_49911604 0.07 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr6_-_161274010 0.07 ENST00000366911.9
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chrX_+_106693838 0.07 ENST00000324342.7
ring finger protein 128
chrX_-_15664798 0.06 ENST00000380342.4
collectrin, amino acid transport regulator
chr8_+_49911396 0.06 ENST00000642720.2
syntrophin gamma 1
chr14_+_22497657 0.06 ENST00000390496.1
T cell receptor alpha joining 41
chr9_-_114806031 0.06 ENST00000374045.5
TNF superfamily member 15
chr6_-_161274042 0.06 ENST00000320285.9
1-acylglycerol-3-phosphate O-acyltransferase 4
chr2_+_127646145 0.06 ENST00000486700.2
ENST00000272644.7
G protein-coupled receptor 17
chr4_-_115113822 0.06 ENST00000613194.4
N-deacetylase and N-sulfotransferase 4
chr11_+_10455292 0.06 ENST00000396553.6
adenosine monophosphate deaminase 3
chr15_+_74788542 0.06 ENST00000567571.5
C-terminal Src kinase
chr12_-_89352395 0.06 ENST00000308385.6
dual specificity phosphatase 6
chr13_-_94479671 0.06 ENST00000377028.10
ENST00000446125.1
dopachrome tautomerase
chr6_-_155455830 0.06 ENST00000159060.3
NADPH oxidase 3
chr1_-_152414256 0.06 ENST00000271835.3
cornulin
chrX_-_21658324 0.06 ENST00000379499.3
kelch like family member 34
chr12_-_16608073 0.06 ENST00000441439.6
LIM domain only 3
chr6_+_29301701 0.06 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr18_+_58341038 0.06 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr14_+_71586261 0.06 ENST00000358550.6
signal induced proliferation associated 1 like 1
chr11_+_35176575 0.06 ENST00000526000.6
CD44 molecule (Indian blood group)
chr7_-_22193824 0.06 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr11_+_34642366 0.05 ENST00000532302.1
ETS homologous factor
chr18_+_78979811 0.05 ENST00000537592.7
spalt like transcription factor 3
chr3_-_33645433 0.05 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr12_+_19205294 0.05 ENST00000424268.5
pleckstrin homology domain containing A5
chr2_+_112095189 0.05 ENST00000649734.1
transmembrane protein 87B
chr18_+_31376777 0.05 ENST00000308128.9
ENST00000359747.4
desmoglein 4
chr3_-_27722699 0.05 ENST00000461503.2
eomesodermin
chr4_-_122621011 0.05 ENST00000611104.2
ENST00000648588.1
interleukin 21
chr18_-_55351977 0.05 ENST00000643689.1
transcription factor 4
chr2_+_158968608 0.05 ENST00000263635.8
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr11_-_117877463 0.05 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr4_+_113292925 0.05 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr11_-_124445696 0.05 ENST00000642064.1
olfactory receptor family 8 subfamily B member 8
chr18_-_36129305 0.05 ENST00000269187.10
ENST00000590986.5
ENST00000440549.6
solute carrier family 39 member 6
chr19_+_12938598 0.05 ENST00000586760.2
ENST00000316448.10
ENST00000588454.6
calreticulin
chr4_+_113292838 0.05 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr6_-_39725387 0.05 ENST00000287152.12
kinesin family member 6
chr9_+_470291 0.05 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr11_+_34642468 0.05 ENST00000527935.1
ETS homologous factor
chr8_-_109648825 0.05 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
syntabulin
chr19_-_14979848 0.05 ENST00000594383.2
solute carrier family 1 member 6
chr21_-_30166782 0.05 ENST00000286808.5
claudin 17
chr12_-_16608183 0.05 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr9_-_122227525 0.05 ENST00000373755.6
ENST00000373754.6
LIM homeobox 6
chr7_+_117020191 0.05 ENST00000434836.5
ENST00000393443.5
ENST00000465133.5
ENST00000477742.5
ENST00000393444.7
ENST00000393447.8
suppression of tumorigenicity 7
chr3_-_108529322 0.05 ENST00000273353.4
myosin heavy chain 15
chrX_-_18672101 0.04 ENST00000379984.4
retinoschisin 1
chr3_-_191282383 0.04 ENST00000427544.6
urotensin 2B
chr6_-_116060859 0.04 ENST00000606080.2
fyn related Src family tyrosine kinase
chr9_+_127264740 0.04 ENST00000373387.9
GTPase activating Rap/RanGAP domain like 3
chr7_-_22194709 0.04 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr18_-_55422306 0.04 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr8_-_17722217 0.04 ENST00000381861.7
microtubule associated scaffold protein 1
chr14_-_36582593 0.04 ENST00000258829.6
NK2 homeobox 8
chr3_+_120908072 0.04 ENST00000273666.10
ENST00000471454.6
ENST00000472879.5
ENST00000497029.5
ENST00000492541.5
syntaxin binding protein 5 like
chr3_-_27722316 0.04 ENST00000449599.4
eomesodermin
chr16_+_81645352 0.04 ENST00000398040.8
c-Maf inducing protein
chr12_-_95116967 0.04 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr18_-_55402187 0.04 ENST00000630268.2
ENST00000570177.6
transcription factor 4
chr17_+_50165990 0.04 ENST00000262018.8
ENST00000344627.10
ENST00000682109.1
ENST00000504073.2
sarcoglycan alpha
chr11_+_5389377 0.04 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr3_-_114179052 0.04 ENST00000383673.5
ENST00000295881.9
dopamine receptor D3
chr13_-_83882390 0.04 ENST00000377084.3
SLIT and NTRK like family member 1
chr4_-_110641920 0.04 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
paired like homeodomain 2
chr2_-_29074515 0.04 ENST00000331664.6
photoreceptor cilium actin regulator
chr1_+_99646025 0.04 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr1_-_150765735 0.04 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr21_-_30881572 0.04 ENST00000332378.6
keratin associated protein 11-1
chr12_+_26195313 0.04 ENST00000422622.3
sarcospan
chr6_+_106360668 0.04 ENST00000633556.3
crystallin beta-gamma domain containing 1
chr4_+_87650277 0.04 ENST00000339673.11
ENST00000282479.8
dentin matrix acidic phosphoprotein 1
chr4_+_94974984 0.04 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr1_-_150765785 0.04 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr12_+_20810698 0.04 ENST00000540853.5
ENST00000381545.8
solute carrier organic anion transporter family member 1B3
chr1_+_81306096 0.04 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr17_-_28406160 0.04 ENST00000618626.1
ENST00000612814.5
solute carrier family 46 member 1
chrX_+_69616067 0.04 ENST00000338901.4
ENST00000525810.5
ENST00000527388.5
ENST00000374553.6
ENST00000374552.9
ENST00000524573.5
ectodysplasin A
chr4_+_41612702 0.04 ENST00000509277.5
LIM and calponin homology domains 1
chr6_-_52087569 0.04 ENST00000340994.4
ENST00000371117.8
PKHD1 ciliary IPT domain containing fibrocystin/polyductin
chr2_-_99255107 0.04 ENST00000333017.6
ENST00000626374.2
ENST00000409679.5
ENST00000423306.1
lysozyme g2
chr1_+_28259473 0.04 ENST00000253063.4
sestrin 2
chr3_-_79767987 0.04 ENST00000464233.6
roundabout guidance receptor 1
chr1_-_93681829 0.04 ENST00000260502.11
BCAR3 adaptor protein, NSP family member
chr6_+_150721073 0.04 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr1_-_92486916 0.03 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr12_-_51028234 0.03 ENST00000547688.7
ENST00000394904.9
solute carrier family 11 member 2
chr7_+_50308672 0.03 ENST00000439701.2
ENST00000438033.5
ENST00000492782.6
IKAROS family zinc finger 1
chr2_+_162318884 0.03 ENST00000446271.5
ENST00000429691.6
grancalcin
chr3_-_123620496 0.03 ENST00000578202.1
myosin light chain kinase
chr1_+_180632001 0.03 ENST00000367590.9
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr9_-_123184233 0.03 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr11_-_107858777 0.03 ENST00000525815.6
solute carrier family 35 member F2
chr4_-_39977836 0.03 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr19_-_35812838 0.03 ENST00000653904.2
proline dehydrogenase 2
chr9_-_128724088 0.03 ENST00000406904.2
ENST00000452105.5
ENST00000372667.9
ENST00000372663.9
zinc finger DHHC-type palmitoyltransferase 12
chr13_-_103066411 0.03 ENST00000245312.5
solute carrier family 10 member 2
chr17_-_40937445 0.03 ENST00000436344.7
ENST00000485751.1
keratin 23

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.1 0.2 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:0072101 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 1.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.2 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.0 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.0 GO:0035993 deltoid tuberosity development(GO:0035993)
0.0 0.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.0 0.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:1902224 ketone body metabolic process(GO:1902224)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.0 GO:0002912 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.1 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.2 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)