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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NR1I2

Z-value: 1.81

Motif logo

Transcription factors associated with NR1I2

Gene Symbol Gene ID Gene Info
ENSG00000144852.20 nuclear receptor subfamily 1 group I member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I2hg38_v1_chr3_+_119782094_119782114-0.216.2e-01Click!

Activity profile of NR1I2 motif

Sorted Z-values of NR1I2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91182652 6.58 ENST00000552145.5
ENST00000546745.5
decorin
chr3_+_157436842 2.69 ENST00000295927.4
pentraxin 3
chr12_-_91182784 2.55 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chr1_+_222928415 2.49 ENST00000284476.7
dispatched RND transporter family member 1
chr12_-_55712402 2.43 ENST00000452168.6
integrin subunit alpha 7
chr10_+_68106109 2.42 ENST00000540630.5
ENST00000354393.6
myopalladin
chr10_-_20897288 2.34 ENST00000377122.9
nebulette
chr12_-_95790755 2.32 ENST00000343702.9
ENST00000344911.8
netrin 4
chr1_+_78490966 2.26 ENST00000370757.8
ENST00000370756.3
prostaglandin F receptor
chr5_+_40679907 2.19 ENST00000302472.4
prostaglandin E receptor 4
chr6_-_46325641 2.18 ENST00000330430.10
ENST00000405162.2
regulator of calcineurin 2
chr5_+_93583212 2.12 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr8_+_37796850 2.06 ENST00000412232.3
adhesion G protein-coupled receptor A2
chr3_+_12288838 1.95 ENST00000455517.6
ENST00000681982.1
peroxisome proliferator activated receptor gamma
chr14_-_52069228 1.94 ENST00000617139.4
nidogen 2
chr11_-_70717994 1.93 ENST00000659264.1
SH3 and multiple ankyrin repeat domains 2
chr14_-_52069039 1.90 ENST00000216286.10
nidogen 2
chrX_+_22136552 1.86 ENST00000682888.1
ENST00000684356.1
phosphate regulating endopeptidase homolog X-linked
chr14_-_89619118 1.78 ENST00000345097.8
ENST00000555855.5
ENST00000555353.5
forkhead box N3
chr6_-_154430495 1.77 ENST00000424998.3
CNKSR family member 3
chr22_-_24245059 1.68 ENST00000398292.3
ENST00000263112.11
ENST00000327365.10
ENST00000424217.1
gamma-glutamyltransferase 5
chr2_-_144430934 1.63 ENST00000638087.1
ENST00000638007.1
zinc finger E-box binding homeobox 2
chr3_+_12289061 1.63 ENST00000652522.1
ENST00000652431.1
ENST00000652098.1
ENST00000651735.1
ENST00000397026.7
peroxisome proliferator activated receptor gamma
chr8_+_37796906 1.62 ENST00000315215.11
adhesion G protein-coupled receptor A2
chr9_-_20382461 1.58 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr6_+_84033717 1.57 ENST00000257776.5
melanocortin 2 receptor accessory protein 2
chr5_+_150190035 1.49 ENST00000230671.7
ENST00000524041.1
solute carrier family 6 member 7
chr2_-_144431001 1.45 ENST00000636413.1
zinc finger E-box binding homeobox 2
chr4_+_123396785 1.42 ENST00000505319.5
ENST00000651917.1
ENST00000610581.4
ENST00000339241.1
sprouty RTK signaling antagonist 1
chr7_-_137846860 1.41 ENST00000288490.9
ENST00000614521.2
ENST00000424189.6
ENST00000446122.5
diacylglycerol kinase iota
chr3_+_155083889 1.41 ENST00000680282.1
membrane metalloendopeptidase
chr3_-_9952337 1.40 ENST00000411976.2
ENST00000412055.6
proline rich transmembrane protein 3
chr13_-_33285682 1.34 ENST00000336934.10
StAR related lipid transfer domain containing 13
chr3_+_155083523 1.32 ENST00000680057.1
membrane metalloendopeptidase
chr13_+_32031300 1.27 ENST00000642040.1
FRY microtubule binding protein
chr22_+_35383106 1.22 ENST00000678411.1
heme oxygenase 1
chr5_-_159099684 1.17 ENST00000380654.8
EBF transcription factor 1
chr2_-_191847068 1.16 ENST00000304141.5
caveolae associated protein 2
chr13_-_32538683 1.15 ENST00000674456.1
ENST00000504114.5
NEDD4 binding protein 2 like 2
chrX_-_150898779 1.14 ENST00000613030.4
ENST00000437787.6
CD99 molecule like 2
chr5_-_159099745 1.14 ENST00000517373.1
EBF transcription factor 1
chr4_-_158173042 1.13 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chrX_-_119693150 1.13 ENST00000394610.7
septin 6
chr7_+_120988683 1.11 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr5_-_159099909 1.11 ENST00000313708.11
EBF transcription factor 1
chr8_-_13514821 1.05 ENST00000276297.9
DLC1 Rho GTPase activating protein
chrX_-_150898592 1.05 ENST00000355149.8
ENST00000466436.5
ENST00000370377.8
CD99 molecule like 2
chr16_+_67173935 1.04 ENST00000566871.5
nucleolar protein 3
chrX_+_9912434 1.04 ENST00000418909.6
shroom family member 2
chr6_+_132570322 1.04 ENST00000275198.1
trace amine associated receptor 6
chrX_+_150363306 1.03 ENST00000370401.7
ENST00000432680.7
mastermind like domain containing 1
chr4_-_158173004 1.03 ENST00000585682.6
golgi associated kinase 1B
chrX_+_150363258 1.03 ENST00000683696.1
mastermind like domain containing 1
chr3_+_8501846 1.02 ENST00000454244.4
LIM and cysteine rich domains 1
chr10_-_43574555 1.02 ENST00000374446.7
ENST00000535642.5
ENST00000426961.1
zinc finger protein 239
chr2_+_30231524 1.01 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr3_+_69936583 1.01 ENST00000314557.10
ENST00000394351.9
melanocyte inducing transcription factor
chr4_-_158159657 1.00 ENST00000590648.5
golgi associated kinase 1B
chr1_+_61082702 0.99 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr21_+_25639272 0.98 ENST00000400532.5
ENST00000312957.9
junctional adhesion molecule 2
chr6_-_166627244 0.98 ENST00000265678.9
ribosomal protein S6 kinase A2
chr16_+_67173971 0.93 ENST00000563258.1
ENST00000568146.1
nucleolar protein 3
chr1_+_42825548 0.91 ENST00000372514.7
erythroblast membrane associated protein (Scianna blood group)
chr3_-_114624193 0.91 ENST00000481632.5
zinc finger and BTB domain containing 20
chr5_-_124745315 0.90 ENST00000306315.9
zinc finger protein 608
chr1_+_164559173 0.90 ENST00000420696.7
PBX homeobox 1
chrX_-_100928903 0.89 ENST00000372956.3
XK related X-linked
chr21_+_25639251 0.86 ENST00000480456.6
junctional adhesion molecule 2
chr10_-_13707536 0.85 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr10_-_24721866 0.84 ENST00000416305.1
ENST00000320481.10
Rho GTPase activating protein 21
chr5_-_124744513 0.83 ENST00000504926.5
zinc finger protein 608
chr6_+_155216637 0.82 ENST00000275246.11
TIAM Rac1 associated GEF 2
chr13_+_48976597 0.82 ENST00000541916.5
fibronectin type III domain containing 3A
chr13_+_32031706 0.79 ENST00000542859.6
FRY microtubule binding protein
chr11_-_111913134 0.78 ENST00000533971.2
ENST00000526180.6
crystallin alpha B
chr11_-_111913195 0.77 ENST00000531198.5
ENST00000616970.5
ENST00000527899.6
crystallin alpha B
chr3_+_8501807 0.76 ENST00000426878.2
ENST00000397386.7
ENST00000415597.5
ENST00000157600.8
LIM and cysteine rich domains 1
chr3_-_49685090 0.76 ENST00000448220.5
macrophage stimulating 1
chr5_-_154850570 0.76 ENST00000326080.10
ENST00000519501.5
ENST00000518651.5
ENST00000517938.5
ENST00000520461.1
fatty acid hydroxylase domain containing 2
chr5_-_128339191 0.76 ENST00000507835.5
fibrillin 2
chr5_+_173918216 0.76 ENST00000519467.1
cytoplasmic polyadenylation element binding protein 4
chr2_-_218568291 0.75 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
ubiquitin specific peptidase 37
chr11_-_111912871 0.75 ENST00000528628.5
crystallin alpha B
chr1_+_148889403 0.75 ENST00000464103.5
ENST00000534536.5
ENST00000369356.8
ENST00000369354.7
ENST00000369347.8
ENST00000369349.7
ENST00000369351.7
phosphodiesterase 4D interacting protein
chr5_+_173918186 0.74 ENST00000657000.1
cytoplasmic polyadenylation element binding protein 4
chr11_-_111923722 0.74 ENST00000527950.5
crystallin alpha B
chr9_-_70869076 0.72 ENST00000677594.1
transient receptor potential cation channel subfamily M member 3
chr3_-_115071333 0.71 ENST00000462705.5
zinc finger and BTB domain containing 20
chr2_+_108621260 0.69 ENST00000409441.5
LIM zinc finger domain containing 1
chr3_-_179251615 0.68 ENST00000314235.9
ENST00000392685.6
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr7_+_150368790 0.68 ENST00000397281.6
ENST00000444957.3
ENST00000466559.1
ENST00000475514.5
ENST00000482680.1
ENST00000488943.1
ENST00000489432.7
ENST00000518514.1
ENST00000478789.5
replication initiator 1
zinc finger protein 775
chr3_+_37243333 0.67 ENST00000431105.1
golgin A4
chr15_+_43517590 0.67 ENST00000300231.6
microtubule associated protein 1A
chr12_+_116738285 0.67 ENST00000392549.7
ENST00000407967.7
ring finger protein, transmembrane 2
chr10_+_133379238 0.65 ENST00000357296.7
ENST00000278060.10
polyamine oxidase
chr12_+_116738308 0.65 ENST00000257575.9
ring finger protein, transmembrane 2
chr5_+_141430499 0.64 ENST00000252085.4
protocadherin gamma subfamily A, 12
chrX_+_103585478 0.63 ENST00000468024.5
ENST00000415568.2
ENST00000472484.6
ENST00000613326.4
ENST00000490644.5
ENST00000459722.1
ENST00000472745.1
ENST00000494801.5
ENST00000434216.2
transcription elongation factor A like 4
chr11_-_108498374 0.63 ENST00000323468.10
protein O-glucosyltransferase 3
chr9_-_120876356 0.61 ENST00000456291.1
PHD finger protein 19
chr14_-_50561119 0.61 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr1_+_236142526 0.61 ENST00000366592.8
G protein-coupled receptor 137B
chr6_-_56851888 0.59 ENST00000312431.10
ENST00000520645.5
dystonin
chr11_-_133845495 0.59 ENST00000299140.8
ENST00000532889.1
spermatogenesis associated 19
chr1_+_61082398 0.59 ENST00000664149.1
nuclear factor I A
chr11_+_308106 0.59 ENST00000399817.9
ENST00000680344.1
interferon induced transmembrane protein 2
chr5_-_38556625 0.59 ENST00000506990.5
ENST00000453190.7
LIF receptor subunit alpha
chr11_-_7963646 0.59 ENST00000328600.3
NLR family pyrin domain containing 10
chr14_+_88385643 0.57 ENST00000393545.9
ENST00000356583.9
ENST00000555401.5
ENST00000553885.5
spermatogenesis associated 7
chr16_+_28863812 0.57 ENST00000684370.1
SH2B adaptor protein 1
chr6_-_152637351 0.57 ENST00000367255.10
spectrin repeat containing nuclear envelope protein 1
chr11_+_307915 0.56 ENST00000616316.2
interferon induced transmembrane protein 2
chr11_+_308217 0.56 ENST00000602569.2
interferon induced transmembrane protein 2
chr11_+_308188 0.55 ENST00000680619.1
ENST00000681833.1
ENST00000680261.1
interferon induced transmembrane protein 2
chr13_+_114234907 0.55 ENST00000375310.5
cell division cycle 16
chr11_+_118607579 0.55 ENST00000530708.4
pleckstrin homology like domain family B member 1
chr14_+_88385714 0.55 ENST00000045347.11
spermatogenesis associated 7
chr7_-_131556602 0.55 ENST00000322985.9
ENST00000378555.8
podocalyxin like
chr14_-_73027117 0.55 ENST00000318876.9
zinc finger FYVE-type containing 1
chr1_+_196819731 0.54 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr18_-_63158208 0.54 ENST00000678301.1
BCL2 apoptosis regulator
chr14_-_73027077 0.52 ENST00000553891.5
ENST00000556143.6
zinc finger FYVE-type containing 1
chr8_-_81112055 0.52 ENST00000220597.4
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr2_+_69013170 0.51 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr14_+_105314711 0.51 ENST00000447393.6
ENST00000547217.5
phosphofurin acidic cluster sorting protein 2
chr11_+_118607598 0.50 ENST00000600882.6
ENST00000356063.9
pleckstrin homology like domain family B member 1
chr11_+_121102666 0.50 ENST00000264037.2
tectorin alpha
chr17_-_10036741 0.50 ENST00000585266.5
growth arrest specific 7
chr9_-_70869029 0.50 ENST00000361823.9
ENST00000377101.5
ENST00000360823.6
ENST00000377105.5
transient receptor potential cation channel subfamily M member 3
chr18_-_500692 0.49 ENST00000400256.5
collectin subfamily member 12
chr1_+_218346235 0.49 ENST00000366929.4
transforming growth factor beta 2
chr5_+_137867852 0.49 ENST00000421631.6
ENST00000239926.9
myotilin
chr7_-_13989658 0.49 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr3_+_184176778 0.49 ENST00000439647.5
adaptor related protein complex 2 subunit mu 1
chr15_+_96332432 0.48 ENST00000559679.1
ENST00000394171.6
nuclear receptor subfamily 2 group F member 2
chr10_+_133379278 0.48 ENST00000480071.2
polyamine oxidase
chr11_-_627173 0.47 ENST00000176195.4
secretin
chr20_+_56358938 0.47 ENST00000371384.4
ENST00000437418.1
family with sequence similarity 210 member B
chr13_+_114235066 0.47 ENST00000252458.6
cell division cycle 16
chr13_+_114234864 0.47 ENST00000360383.7
ENST00000628084.2
ENST00000356221.8
cell division cycle 16
chr5_-_59430600 0.46 ENST00000636120.1
phosphodiesterase 4D
chr16_+_28863757 0.46 ENST00000618521.4
ENST00000359285.9
ENST00000538342.5
SH2B adaptor protein 1
chr12_+_56118241 0.45 ENST00000551790.5
ENST00000552345.1
ENST00000257940.7
ENST00000551880.1
extended synaptotagmin 1
zinc finger CCCH-type containing 10
chr14_-_104953899 0.45 ENST00000557457.1
AHNAK nucleoprotein 2
chr3_+_184176949 0.45 ENST00000432591.5
ENST00000431779.5
ENST00000621863.4
adaptor related protein complex 2 subunit mu 1
chr19_-_4518465 0.45 ENST00000633942.1
perilipin 4
chr9_-_135499846 0.45 ENST00000429260.7
chromosome 9 open reading frame 116
chrX_-_72305892 0.45 ENST00000450875.5
ENST00000417400.1
ENST00000431381.5
ENST00000445983.5
ENST00000651998.1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr9_-_93453540 0.44 ENST00000375412.11
family with sequence similarity 120A opposite strand
chr9_-_71446835 0.44 ENST00000357533.6
transient receptor potential cation channel subfamily M member 3
chr12_-_120446372 0.44 ENST00000546954.2
TP53 regulated inhibitor of apoptosis 1
chr14_+_50560137 0.43 ENST00000358385.12
atlastin GTPase 1
chr19_+_37371092 0.43 ENST00000436120.7
zinc finger protein 527
chr1_+_61082553 0.43 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr11_+_130448633 0.42 ENST00000299164.4
ADAM metallopeptidase with thrombospondin type 1 motif 15
chr13_-_32538819 0.42 ENST00000674452.1
ENST00000674422.1
ENST00000674349.1
ENST00000674465.1
ENST00000674327.1
ENST00000505213.5
ENST00000357505.10
ENST00000399396.7
NEDD4 binding protein 2 like 2
chrX_-_72714181 0.42 ENST00000339490.7
ENST00000541944.5
ENST00000373539.3
phosphorylase kinase regulatory subunit alpha 1
chr1_-_159925496 0.42 ENST00000368097.9
transgelin 2
chr17_+_77141378 0.41 ENST00000587820.1
SEC14 like lipid binding 1
chr13_+_114235044 0.41 ENST00000252457.9
ENST00000375308.5
cell division cycle 16
chr17_+_82228397 0.41 ENST00000584689.6
ENST00000392341.6
solute carrier family 16 member 3
chr2_-_65366650 0.40 ENST00000443619.6
sprouty related EVH1 domain containing 2
chr4_+_113049479 0.40 ENST00000671727.1
ENST00000671762.1
ENST00000672366.1
ENST00000672502.1
ENST00000672045.1
ENST00000672251.1
ENST00000672854.1
ankyrin 2
chr11_-_66677748 0.39 ENST00000525754.5
ENST00000531969.5
ENST00000524637.1
ENST00000531036.2
ENST00000310046.9
RNA binding motif protein 4B
chr15_-_56918571 0.39 ENST00000559000.6
novel protein
chr9_+_128275343 0.39 ENST00000495313.5
ENST00000372898.6
SWI5 homologous recombination repair protein
chr19_+_1248553 0.38 ENST00000586757.5
ENST00000300952.6
ENST00000682408.1
midnolin
chr16_-_28925172 0.38 ENST00000544477.5
ENST00000357573.10
ENST00000358201.9
rabaptin, RAB GTPase binding effector protein 2
chr4_+_147732070 0.38 ENST00000336498.8
Rho GTPase activating protein 10
chr17_-_8162932 0.38 ENST00000488857.5
ENST00000316509.11
ENST00000481878.1
ENST00000498285.1
vesicle associated membrane protein 2
novel protein
chr3_-_186108501 0.38 ENST00000422039.1
ENST00000434744.5
ETS variant transcription factor 5
chr6_+_125781108 0.37 ENST00000368357.7
nuclear receptor coactivator 7
chrX_+_16650155 0.37 ENST00000380200.3
S100 calcium binding protein G
chr12_-_52192007 0.37 ENST00000394815.3
keratin 80
chr12_-_7088848 0.37 ENST00000649804.1
complement C1r
chr7_+_134891400 0.36 ENST00000393118.6
caldesmon 1
chr1_+_149390612 0.35 ENST00000650865.1
ENST00000652191.1
ENST00000621744.4
notch 2 N-terminal like C
novel protein, identical to neuroblastoma breakpoint family, member 19 NBPF19
chr1_+_207104226 0.35 ENST00000367070.8
complement component 4 binding protein alpha
chr2_+_218399838 0.34 ENST00000273062.7
CTD small phosphatase 1
chr5_+_6448832 0.34 ENST00000399816.4
ubiquitin conjugating enzyme E2 Q family like 1
chr9_-_101594918 0.33 ENST00000374806.2
protein phosphatase 3 regulatory subunit B, beta
chr9_-_127874964 0.33 ENST00000373156.5
adenylate kinase 1
chr9_-_128067310 0.33 ENST00000373078.5
nuclear apoptosis inducing factor 1
chr1_-_162023826 0.32 ENST00000294794.8
olfactomedin like 2B
chr15_+_96333111 0.32 ENST00000453270.2
nuclear receptor subfamily 2 group F member 2
chr9_-_128204218 0.32 ENST00000634901.1
ENST00000372948.7
CDKN1A interacting zinc finger protein 1
chr1_-_15944348 0.31 ENST00000444358.1
zinc finger and BTB domain containing 17
chr4_+_99574812 0.31 ENST00000422897.6
ENST00000265517.10
microsomal triglyceride transfer protein
chr8_+_61287950 0.31 ENST00000519846.5
ENST00000325897.5
ENST00000523868.2
ENST00000518592.5
clavesin 1
chr1_-_156677400 0.31 ENST00000368223.4
nestin
chr11_+_73342906 0.30 ENST00000643371.1
Rho guanine nucleotide exchange factor 17
chr1_-_146229000 0.30 ENST00000612520.2
ENST00000579793.6
ENST00000362074.7
NBPF member 10
notch 2 N-terminal like A
chr16_+_47461314 0.30 ENST00000299167.12
ENST00000323584.10
ENST00000563376.5
phosphorylase kinase regulatory subunit beta
chr9_+_35829217 0.30 ENST00000439587.6
ENST00000643932.2
ENST00000650015.1
ENST00000377991.9
transmembrane protein 8B
chr6_-_31897200 0.30 ENST00000395728.7
ENST00000375528.8
euchromatic histone lysine methyltransferase 2
chr19_-_52008081 0.30 ENST00000602063.5
ENST00000597747.5
ENST00000594083.5
ENST00000593650.5
ENST00000599631.5
ENST00000598071.6
ENST00000601178.5
ENST00000376716.9
ENST00000391795.7
zinc finger protein 615
chr4_-_151325488 0.29 ENST00000604030.7
SH3 domain containing 19
chr17_-_7179544 0.29 ENST00000619926.4
asialoglycoprotein receptor 1
chr12_-_52191981 0.29 ENST00000313234.9
keratin 80
chr16_+_47461290 0.29 ENST00000566044.5
phosphorylase kinase regulatory subunit beta

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.8 2.5 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.8 12.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.7 2.2 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.7 2.0 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.5 2.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.5 3.6 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.5 1.9 GO:1904383 response to sodium phosphate(GO:1904383)
0.4 1.2 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.4 2.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 3.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.4 1.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.3 1.1 GO:0046203 putrescine catabolic process(GO:0009447) spermidine catabolic process(GO:0046203)
0.3 2.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.2 2.3 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.2 1.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 1.0 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.2 0.8 GO:0009956 radial pattern formation(GO:0009956)
0.2 3.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.5 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.2 0.5 GO:0090274 positive regulation of pancreatic juice secretion(GO:0090187) regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.7 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 1.4 GO:0046959 habituation(GO:0046959)
0.1 0.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 2.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.5 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 1.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 1.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 1.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 4.5 GO:0071711 basement membrane organization(GO:0071711)
0.1 2.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:0071105 response to interleukin-11(GO:0071105)
0.1 1.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.3 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 2.3 GO:0072189 ureter development(GO:0072189)
0.1 4.0 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 2.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.3 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.8 GO:0036309 protein localization to M-band(GO:0036309)
0.1 0.6 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 1.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 1.7 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 1.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.6 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.8 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.2 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 0.6 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.7 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0072573 tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.4 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.4 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 1.9 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 1.8 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.0 0.3 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.3 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.5 GO:0072553 terminal button organization(GO:0072553)
0.0 0.5 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.2 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.8 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0015847 putrescine transport(GO:0015847)
0.0 1.2 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.9 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.4 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 1.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.0 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.2 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.5 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.9 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 2.6 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.1 GO:0072179 regulation of branch elongation involved in ureteric bud branching(GO:0072095) nephric duct formation(GO:0072179) mesonephric duct morphogenesis(GO:0072180)
0.0 1.7 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.4 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.0 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.2 GO:0051343 positive regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051343)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.8 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.3 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.5 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 1.0 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.0 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.1 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.0 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.0 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.0 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445) positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 1.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 2.8 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.9 GO:0005883 neurofilament(GO:0005883)
0.1 1.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.4 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.1 0.3 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.4 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.7 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 2.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 5.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.0 1.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.7 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 3.9 GO:0005901 caveola(GO:0005901)
0.0 1.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.9 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 4.1 GO:0030175 filopodium(GO:0030175)
0.0 5.7 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 1.9 GO:0005811 lipid particle(GO:0005811)
0.0 2.8 GO:0005903 brush border(GO:0005903)
0.0 3.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 1.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.5 1.6 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.3 3.6 GO:0050692 DBD domain binding(GO:0050692)
0.3 2.6 GO:0001849 complement component C1q binding(GO:0001849)
0.3 1.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.3 2.3 GO:0043237 laminin-1 binding(GO:0043237)
0.2 1.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 1.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 2.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 2.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.2 1.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 1.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 2.0 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.6 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 2.5 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.7 GO:0039552 RIG-I binding(GO:0039552)
0.1 9.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 3.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.7 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 2.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 2.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 3.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 4.6 GO:0005518 collagen binding(GO:0005518)
0.0 1.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 2.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 4.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 1.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.9 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 6.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 3.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 4.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 3.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 9.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 7.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 2.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling