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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for NR5A2

Z-value: 0.84

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Transcription factors associated with NR5A2

Gene Symbol Gene ID Gene Info
NR5A2
ENSG00000116833.14 nuclear receptor subfamily 5 group A member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR5A2hg38_v1_chr1_+_200027702_200027716-0.714.7e-02Click!

Activity profile of NR5A2 motif

Sorted Z-values of NR5A2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_59577463 1.34 ENST00000359926.7
PHACTR3
phosphatase and actin regulator 3
chr10_+_116427839 0.86 ENST00000369230.4
PNLIPRP3
pancreatic lipase related protein 3
chr20_+_59604527 0.82 ENST00000371015.6
PHACTR3
phosphatase and actin regulator 3
chr2_+_219627394 0.77 ENST00000373760.6
SLC4A3
solute carrier family 4 member 3
chr15_+_43593054 0.71 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43692886 0.69 ENST00000434505.5
ENST00000411750.5
CKMT1A
creatine kinase, mitochondrial 1A
chr6_-_136526177 0.56 ENST00000617204.4
MAP7
microtubule associated protein 7
chr6_-_136525961 0.45 ENST00000438100.6
MAP7
microtubule associated protein 7
chr11_-_72785932 0.45 ENST00000539138.1
ENST00000542989.5
STARD10
StAR related lipid transfer domain containing 10
chr22_+_39994926 0.42 ENST00000333407.11
FAM83F
family with sequence similarity 83 member F
chr3_-_49903863 0.41 ENST00000296474.8
ENST00000621387.4
MST1R
macrophage stimulating 1 receptor
chr2_+_219627565 0.41 ENST00000273063.10
SLC4A3
solute carrier family 4 member 3
chr6_+_30888672 0.39 ENST00000446312.5
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_+_219627650 0.39 ENST00000317151.7
SLC4A3
solute carrier family 4 member 3
chr2_+_219627622 0.38 ENST00000358055.8
SLC4A3
solute carrier family 4 member 3
chr12_-_106138946 0.38 ENST00000261402.7
NUAK1
NUAK family kinase 1
chr11_+_10450627 0.38 ENST00000396554.7
ENST00000524866.5
AMPD3
adenosine monophosphate deaminase 3
chr15_-_82952683 0.37 ENST00000450735.7
ENST00000304231.12
HOMER2
homer scaffold protein 2
chr1_+_152908538 0.35 ENST00000368764.4
IVL
involucrin
chr2_-_237590660 0.34 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr9_-_114806031 0.34 ENST00000374045.5
TNFSF15
TNF superfamily member 15
chr15_+_45129933 0.33 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
DUOX1
dual oxidase 1
chr15_-_81324130 0.33 ENST00000302824.7
STARD5
StAR related lipid transfer domain containing 5
chr19_+_48270079 0.32 ENST00000595607.6
ZNF114
zinc finger protein 114
chr8_+_22053543 0.31 ENST00000519850.5
ENST00000381470.7
DMTN
dematin actin binding protein
chr17_-_29176752 0.30 ENST00000533112.5
MYO18A
myosin XVIIIA
chr5_+_52989314 0.30 ENST00000296585.10
ITGA2
integrin subunit alpha 2
chr11_+_59713403 0.30 ENST00000641815.1
STX3
syntaxin 3
chr1_-_11654422 0.30 ENST00000354287.5
FBXO2
F-box protein 2
chr19_+_45340736 0.29 ENST00000391946.7
KLC3
kinesin light chain 3
chr19_+_45340760 0.29 ENST00000585434.5
KLC3
kinesin light chain 3
chr2_-_31138429 0.29 ENST00000349752.10
GALNT14
polypeptide N-acetylgalactosaminyltransferase 14
chr19_+_14941489 0.28 ENST00000248072.3
OR7C2
olfactory receptor family 7 subfamily C member 2
chr10_-_75235917 0.28 ENST00000469299.1
ENST00000372538.8
COMTD1
catechol-O-methyltransferase domain containing 1
chr14_-_23155302 0.28 ENST00000529705.6
SLC7A8
solute carrier family 7 member 8
chr12_-_56488350 0.27 ENST00000623608.3
ENST00000610413.4
GLS2
glutaminase 2
chr2_-_237590694 0.27 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17
RAB17, member RAS oncogene family
chr12_+_132490140 0.26 ENST00000680143.1
FBRSL1
fibrosin like 1
chr10_-_86969178 0.26 ENST00000440490.1
ENST00000609457.5
ADIRF-AS1
MMRN2
ADIRF antisense RNA 1
multimerin 2
chr3_+_113947901 0.25 ENST00000330212.7
ENST00000498275.5
ZDHHC23
zinc finger DHHC-type palmitoyltransferase 23
chr1_+_15756659 0.25 ENST00000375771.5
FBLIM1
filamin binding LIM protein 1
chr12_+_100794769 0.25 ENST00000392977.8
ENST00000546991.1
ENST00000392979.7
ANO4
anoctamin 4
chr19_+_2249317 0.25 ENST00000221496.5
AMH
anti-Mullerian hormone
chr15_-_51243011 0.25 ENST00000405913.7
ENST00000559878.5
CYP19A1
cytochrome P450 family 19 subfamily A member 1
chr3_+_186996444 0.25 ENST00000676633.1
ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr3_-_121660892 0.24 ENST00000428394.6
ENST00000314583.8
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_+_43836043 0.24 ENST00000266534.8
ENST00000551577.5
TMEM117
transmembrane protein 117
chr7_+_130266847 0.24 ENST00000222481.9
CPA2
carboxypeptidase A2
chr17_-_40501615 0.24 ENST00000254051.11
TNS4
tensin 4
chr22_+_48693204 0.23 ENST00000406880.1
TAFA5
TAFA chemokine like family member 5
chr22_+_44677044 0.23 ENST00000006251.11
PRR5
proline rich 5
chr1_+_32765667 0.23 ENST00000373480.1
KIAA1522
KIAA1522
chr22_+_44677077 0.23 ENST00000403581.5
PRR5
proline rich 5
chr22_+_44676808 0.23 ENST00000624862.3
PRR5
proline rich 5
chr3_+_113948004 0.23 ENST00000638807.2
ZDHHC23
zinc finger DHHC-type palmitoyltransferase 23
chr19_+_45340774 0.23 ENST00000589837.5
KLC3
kinesin light chain 3
chr21_+_42219123 0.22 ENST00000398449.8
ABCG1
ATP binding cassette subfamily G member 1
chr2_+_46297397 0.22 ENST00000263734.5
EPAS1
endothelial PAS domain protein 1
chr4_-_170026371 0.22 ENST00000361618.4
ENST00000506764.1
MFAP3L
microfibril associated protein 3 like
chr17_+_32487686 0.22 ENST00000584792.5
CDK5R1
cyclin dependent kinase 5 regulatory subunit 1
chr5_-_60844185 0.21 ENST00000505959.5
ELOVL7
ELOVL fatty acid elongase 7
chr16_+_67431112 0.21 ENST00000326152.6
HSD11B2
hydroxysteroid 11-beta dehydrogenase 2
chr21_+_42219111 0.21 ENST00000450121.5
ENST00000361802.6
ABCG1
ATP binding cassette subfamily G member 1
chr10_+_79347491 0.19 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr11_-_72642450 0.19 ENST00000444035.6
ENST00000544570.5
PDE2A
phosphodiesterase 2A
chr4_-_170026333 0.19 ENST00000504999.1
MFAP3L
microfibril associated protein 3 like
chr11_-_72642407 0.19 ENST00000376450.7
PDE2A
phosphodiesterase 2A
chr15_+_90184912 0.19 ENST00000561085.1
ENST00000332496.10
SEMA4B
semaphorin 4B
chr21_+_38272291 0.18 ENST00000438657.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr16_-_84239750 0.18 ENST00000568181.1
KCNG4
potassium voltage-gated channel modifier subfamily G member 4
chr22_-_39244969 0.18 ENST00000331163.11
PDGFB
platelet derived growth factor subunit B
chr10_-_49762335 0.17 ENST00000419399.4
ENST00000432695.2
OGDHL
oxoglutarate dehydrogenase L
chr2_-_236507428 0.17 ENST00000409907.8
IQCA1
IQ motif containing with AAA domain 1
chr8_-_130016414 0.17 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYRIB
CYFIP related Rac1 interactor B
chr1_+_207053229 0.17 ENST00000367080.8
ENST00000367079.3
PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr2_+_233195433 0.17 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase D
chr17_+_7705193 0.17 ENST00000226091.3
EFNB3
ephrin B3
chr6_-_27132750 0.16 ENST00000607124.1
ENST00000339812.3
H2BC11
H2B clustered histone 11
chr14_+_93927259 0.16 ENST00000556222.1
ENST00000554404.1
FAM181A
family with sequence similarity 181 member A
chr2_-_236507515 0.16 ENST00000309507.9
IQCA1
IQ motif containing with AAA domain 1
chr19_-_42877988 0.16 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr6_-_143511682 0.16 ENST00000002165.11
FUCA2
alpha-L-fucosidase 2
chr17_+_7439504 0.16 ENST00000575331.1
ENST00000293829.9
ENSG00000272884.1
FGF11
novel transcript
fibroblast growth factor 11
chr5_-_16616972 0.16 ENST00000682564.1
ENST00000306320.10
ENST00000682229.1
RETREG1
reticulophagy regulator 1
chr5_-_16617085 0.16 ENST00000684521.1
RETREG1
reticulophagy regulator 1
chr4_-_75630473 0.15 ENST00000307465.9
CDKL2
cyclin dependent kinase like 2
chr6_+_116461364 0.15 ENST00000368606.7
ENST00000368605.3
CALHM6
calcium homeostasis modulator family member 6
chr1_+_26543106 0.15 ENST00000530003.5
RPS6KA1
ribosomal protein S6 kinase A1
chr1_-_85048437 0.15 ENST00000341115.8
ENST00000370587.5
ENST00000370589.7
MCOLN3
mucolipin TRP cation channel 3
chrX_+_49058966 0.15 ENST00000496529.6
ENST00000606812.5
ENST00000603986.6
ENST00000536628.3
CCDC120
coiled-coil domain containing 120
chr17_+_50508384 0.15 ENST00000436259.6
ENST00000652471.1
ENST00000323776.11
ENST00000419930.2
MYCBPAP
MYCBP associated protein
chr16_-_4538469 0.15 ENST00000588381.1
ENST00000563332.6
CDIP1
cell death inducing p53 target 1
chr11_+_66291887 0.14 ENST00000327259.5
TMEM151A
transmembrane protein 151A
chr19_-_51026593 0.14 ENST00000600362.5
ENST00000453757.8
ENST00000601671.1
KLK11
kallikrein related peptidase 11
chr1_+_42153399 0.14 ENST00000372581.2
GUCA2B
guanylate cyclase activator 2B
chr1_-_149886652 0.14 ENST00000369155.3
H2BC21
H2B clustered histone 21
chr22_+_26483851 0.14 ENST00000215917.11
SRRD
SRR1 domain containing
chr12_-_7092422 0.14 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
C1R
complement C1r
chrX_-_49200174 0.14 ENST00000472598.5
ENST00000263233.9
ENST00000479808.5
SYP
synaptophysin
chr15_+_64911869 0.14 ENST00000319580.13
ENST00000496660.5
ANKDD1A
ankyrin repeat and death domain containing 1A
chr19_+_41797147 0.14 ENST00000596544.1
CEACAM3
CEA cell adhesion molecule 3
chr3_-_122793772 0.13 ENST00000306103.3
HSPBAP1
HSPB1 associated protein 1
chr11_-_124897797 0.13 ENST00000306534.8
ENST00000533054.5
ROBO4
roundabout guidance receptor 4
chr17_-_4560564 0.13 ENST00000574584.1
ENST00000381550.8
ENST00000301395.7
GGT6
gamma-glutamyltransferase 6
chr9_-_129178247 0.13 ENST00000372491.4
IER5L
immediate early response 5 like
chr21_+_38272410 0.13 ENST00000398934.5
ENST00000398930.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr16_-_66918839 0.13 ENST00000565235.2
ENST00000568632.5
ENST00000565796.5
CDH16
cadherin 16
chr5_+_66958870 0.13 ENST00000405643.5
ENST00000407621.1
ENST00000432426.5
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_-_147225309 0.13 ENST00000369272.7
ENST00000254090.9
ENST00000441068.6
FMO5
flavin containing dimethylaniline monoxygenase 5
chr10_+_116324440 0.13 ENST00000333254.4
CCDC172
coiled-coil domain containing 172
chr10_+_72893734 0.13 ENST00000334011.10
OIT3
oncoprotein induced transcript 3
chr21_+_38272250 0.13 ENST00000398932.5
KCNJ15
potassium inwardly rectifying channel subfamily J member 15
chr16_-_66918876 0.13 ENST00000570262.5
ENST00000299752.9
ENST00000394055.7
CDH16
cadherin 16
chr1_+_32741779 0.13 ENST00000401073.7
KIAA1522
KIAA1522
chr6_+_89080739 0.13 ENST00000369472.1
ENST00000336032.4
PNRC1
proline rich nuclear receptor coactivator 1
chr13_-_110561668 0.13 ENST00000267328.5
RAB20
RAB20, member RAS oncogene family
chr17_+_7435416 0.13 ENST00000323206.2
ENST00000396568.1
TMEM102
transmembrane protein 102
chr12_+_6385119 0.13 ENST00000541102.1
LTBR
lymphotoxin beta receptor
chr3_-_10708007 0.13 ENST00000646379.1
ATP2B2
ATPase plasma membrane Ca2+ transporting 2
chr4_-_170027209 0.13 ENST00000393702.7
MFAP3L
microfibril associated protein 3 like
chr7_+_75398142 0.13 ENST00000447409.6
TRIM73
tripartite motif containing 73
chr10_+_79347460 0.12 ENST00000225174.8
PPIF
peptidylprolyl isomerase F
chr15_+_59438149 0.12 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
FAM81A
family with sequence similarity 81 member A
chr6_+_27815010 0.12 ENST00000621112.2
H2BC14
H2B clustered histone 14
chr10_+_23439060 0.12 ENST00000376495.5
OTUD1
OTU deubiquitinase 1
chr12_+_56338873 0.12 ENST00000228534.6
IL23A
interleukin 23 subunit alpha
chr7_+_48089257 0.12 ENST00000436673.5
ENST00000395564.9
UPP1
uridine phosphorylase 1
chr17_+_1742836 0.12 ENST00000324015.7
ENST00000450523.6
ENST00000453723.5
ENST00000453066.6
ENST00000382061.5
SERPINF2
serpin family F member 2
chr17_-_40100569 0.12 ENST00000246672.4
NR1D1
nuclear receptor subfamily 1 group D member 1
chr4_+_73436198 0.12 ENST00000395792.7
AFP
alpha fetoprotein
chr8_-_130016395 0.12 ENST00000523509.5
CYRIB
CYFIP related Rac1 interactor B
chr14_-_103522696 0.12 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
CKB
creatine kinase B
chr2_-_175181663 0.12 ENST00000392541.3
ENST00000284727.9
ENST00000409194.5
ATP5MC3
ATP synthase membrane subunit c locus 3
chr8_+_124539097 0.12 ENST00000606244.2
ENST00000276689.8
ENST00000518008.5
ENST00000517367.1
NDUFB9
NADH:ubiquinone oxidoreductase subunit B9
chr19_-_17026795 0.12 ENST00000443236.7
CPAMD8
C3 and PZP like alpha-2-macroglobulin domain containing 8
chr7_-_72966953 0.12 ENST00000395244.5
TRIM74
tripartite motif containing 74
chr4_+_73436244 0.12 ENST00000226359.2
AFP
alpha fetoprotein
chr1_+_115976488 0.12 ENST00000369503.9
SLC22A15
solute carrier family 22 member 15
chr17_-_75509880 0.11 ENST00000433559.6
CASKIN2
CASK interacting protein 2
chr22_-_29315656 0.11 ENST00000401450.3
ENST00000216101.7
RASL10A
RAS like family 10 member A
chr1_+_43979179 0.11 ENST00000434555.7
ENST00000372324.6
ENST00000481924.2
B4GALT2
beta-1,4-galactosyltransferase 2
chr4_-_10457385 0.11 ENST00000507515.1
ENST00000326756.4
ZNF518B
zinc finger protein 518B
chr8_+_102551583 0.11 ENST00000285402.4
ODF1
outer dense fiber of sperm tails 1
chr18_-_31162849 0.11 ENST00000257197.7
ENST00000257198.6
DSC1
desmocollin 1
chr2_+_219442023 0.11 ENST00000431523.5
ENST00000396698.5
SPEG
striated muscle enriched protein kinase
chr20_+_1895365 0.11 ENST00000358771.5
SIRPA
signal regulatory protein alpha
chr17_-_2711736 0.11 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
CLUH
clustered mitochondria homolog
chr1_-_149842736 0.11 ENST00000369159.2
H2AC18
H2A clustered histone 18
chr1_+_19596960 0.11 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
MICOS10
NBL1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chr6_+_143864458 0.11 ENST00000237275.9
ZC2HC1B
zinc finger C2HC-type containing 1B
chr14_-_21023318 0.11 ENST00000298684.9
ENST00000557169.5
ENST00000553563.5
NDRG2
NDRG family member 2
chr6_-_42194947 0.11 ENST00000230361.4
GUCA1B
guanylate cyclase activator 1B
chr3_-_108953870 0.11 ENST00000261047.8
GUCA1C
guanylate cyclase activator 1C
chr11_+_7576408 0.11 ENST00000533792.5
PPFIBP2
PPFIA binding protein 2
chr3_+_49689531 0.11 ENST00000432042.5
ENST00000454491.5
ENST00000327697.11
RNF123
ring finger protein 123
chr2_-_241637045 0.11 ENST00000407315.6
THAP4
THAP domain containing 4
chr12_+_57583101 0.11 ENST00000674858.1
ENST00000675433.1
ENST00000674980.1
KIF5A
kinesin family member 5A
chr14_-_21022817 0.11 ENST00000554104.5
NDRG2
NDRG family member 2
chr1_+_32251239 0.11 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK
LCK proto-oncogene, Src family tyrosine kinase
chr8_-_130016622 0.10 ENST00000518283.5
ENST00000519110.5
CYRIB
CYFIP related Rac1 interactor B
chr2_+_176269406 0.10 ENST00000249442.11
ENST00000443241.5
MTX2
metaxin 2
chr4_-_73998669 0.10 ENST00000296027.5
CXCL5
C-X-C motif chemokine ligand 5
chr17_-_29589536 0.10 ENST00000394869.7
GIT1
GIT ArfGAP 1
chr19_-_17245889 0.10 ENST00000291442.4
NR2F6
nuclear receptor subfamily 2 group F member 6
chr22_+_46150590 0.10 ENST00000262735.9
ENST00000420804.5
PPARA
peroxisome proliferator activated receptor alpha
chr11_-_95232514 0.10 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
SESN3
sestrin 3
chr14_-_91060113 0.10 ENST00000536315.6
RPS6KA5
ribosomal protein S6 kinase A5
chr2_+_237966955 0.10 ENST00000414443.5
ENST00000448502.5
ENST00000416292.5
ENST00000409633.5
ENST00000272930.9
ENST00000409953.5
ENST00000409332.5
UBE2F
ubiquitin conjugating enzyme E2 F (putative)
chr17_-_29589606 0.10 ENST00000225394.8
GIT1
GIT ArfGAP 1
chr8_-_58500158 0.10 ENST00000301645.4
CYP7A1
cytochrome P450 family 7 subfamily A member 1
chr7_+_151085858 0.10 ENST00000463381.5
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr19_+_44748673 0.10 ENST00000164227.10
BCL3
BCL3 transcription coactivator
chr14_-_103521342 0.10 ENST00000553610.5
CKB
creatine kinase B
chr20_-_45631235 0.09 ENST00000326000.2
WFDC9
WAP four-disulfide core domain 9
chr11_+_26332117 0.09 ENST00000531646.1
ENST00000256737.8
ANO3
anoctamin 3
chr8_+_144095054 0.09 ENST00000318911.5
CYC1
cytochrome c1
chr21_+_41167774 0.09 ENST00000328735.10
ENST00000347667.5
BACE2
beta-secretase 2
chr5_+_141051374 0.09 ENST00000306549.6
PCDHB1
protocadherin beta 1
chr5_+_141637398 0.09 ENST00000518856.1
RELL2
RELT like 2
chr1_+_110210272 0.09 ENST00000438661.3
KCNC4
potassium voltage-gated channel subfamily C member 4
chr7_+_55964577 0.09 ENST00000446778.5
ENST00000322090.8
NIPSNAP2
nipsnap homolog 2
chr16_+_641792 0.09 ENST00000307650.9
ENST00000629534.2
MCRIP2
MAPK regulated corepressor interacting protein 2
chr9_-_127916978 0.09 ENST00000361444.3
ENST00000335791.10
ST6GALNAC4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chrX_+_48786578 0.09 ENST00000376670.9
GATA1
GATA binding protein 1
chr12_-_109833373 0.09 ENST00000261740.7
TRPV4
transient receptor potential cation channel subfamily V member 4
chrX_+_155026835 0.09 ENST00000369498.8
FUNDC2
FUN14 domain containing 2
chr17_-_58007217 0.09 ENST00000258962.5
ENST00000582730.6
ENST00000584773.5
ENST00000585096.1
SRSF1
serine and arginine rich splicing factor 1
chr16_-_58295019 0.09 ENST00000567164.6
ENST00000219301.8
ENST00000569727.1
PRSS54
serine protease 54
chr20_+_43916142 0.09 ENST00000423191.6
ENST00000372999.5
TOX2
TOX high mobility group box family member 2
chr20_+_54475584 0.09 ENST00000262593.10
DOK5
docking protein 5
chr7_-_945799 0.09 ENST00000611167.4
ADAP1
ArfGAP with dual PH domains 1
chr17_-_40937445 0.09 ENST00000436344.7
ENST00000485751.1
KRT23
keratin 23
chr5_-_74866958 0.09 ENST00000389156.9
FAM169A
family with sequence similarity 169 member A
chr17_-_8087709 0.09 ENST00000647874.1
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr14_+_92513766 0.09 ENST00000216487.12
ENST00000620541.4
ENST00000557762.1
RIN3
Ras and Rab interactor 3
chr18_+_44680875 0.09 ENST00000649279.2
ENST00000677699.1
SETBP1
SET binding protein 1
chr3_+_4493340 0.09 ENST00000357086.10
ENST00000354582.12
ENST00000649015.2
ENST00000467056.6
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr18_+_44680093 0.09 ENST00000426838.8
ENST00000677068.1
SETBP1
SET binding protein 1
chr10_-_123008784 0.09 ENST00000368886.10
IKZF5
IKAROS family zinc finger 5
chr11_-_1762403 0.09 ENST00000367196.4
CTSD
cathepsin D

Network of associatons between targets according to the STRING database.

First level regulatory network of NR5A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.4 GO:0009720 detection of hormone stimulus(GO:0009720)
0.1 0.3 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.3 GO:0042335 cuticle development(GO:0042335)
0.1 0.4 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.2 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 1.0 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.4 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.2 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.2 GO:0072209 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.2 GO:0030221 basophil differentiation(GO:0030221)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.4 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.4 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.4 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:0070859 circadian temperature homeostasis(GO:0060086) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 0.6 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.1 GO:0035645 enteric smooth muscle cell differentiation(GO:0035645)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:0002339 B cell selection(GO:0002339)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 1.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.0 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.3 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.0 0.1 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.0 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.0 GO:0060406 maternal aggressive behavior(GO:0002125) positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.0 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.7 GO:0008088 axo-dendritic transport(GO:0008088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.9 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 0.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.7 GO:0038064 collagen receptor activity(GO:0038064)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 2.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.2 GO:0010465 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0008443 6-phosphofructokinase activity(GO:0003872) phosphofructokinase activity(GO:0008443)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0050733 DNA topoisomerase binding(GO:0044547) RS domain binding(GO:0050733)
0.0 0.0 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)