Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
KLF4 | hg38_v1_chr9_-_107489754_107489776 | -0.79 | 1.9e-02 | Click! |
PATZ1 | hg38_v1_chr22_-_31345770_31345785 | -0.41 | 3.1e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.2 | 13.2 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
0.3 | 11.2 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
1.1 | 9.7 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
0.1 | 8.5 | GO:0070268 | cornification(GO:0070268) |
0.1 | 7.8 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
0.4 | 7.0 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.0 | 5.9 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.9 | 5.5 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
0.3 | 5.3 | GO:0021894 | cerebral cortex GABAergic interneuron development(GO:0021894) |
0.1 | 5.0 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 30.2 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.6 | 13.2 | GO:0005861 | troponin complex(GO:0005861) |
0.0 | 12.1 | GO:0005739 | mitochondrion(GO:0005739) |
0.0 | 10.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.1 | 9.4 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 7.7 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.0 | 7.5 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.1 | 7.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.2 | 6.9 | GO:0030057 | desmosome(GO:0030057) |
0.3 | 6.8 | GO:0031932 | TORC2 complex(GO:0031932) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 21.8 | GO:0001012 | RNA polymerase II regulatory region DNA binding(GO:0001012) |
0.1 | 13.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.9 | 12.8 | GO:0031014 | troponin T binding(GO:0031014) |
1.5 | 12.3 | GO:0008934 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
0.0 | 9.9 | GO:0003924 | GTPase activity(GO:0003924) |
0.1 | 8.6 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 8.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 7.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.1 | 7.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.2 | 6.0 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 16.1 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.1 | 8.4 | PID MTOR 4PATHWAY | mTOR signaling pathway |
0.1 | 6.7 | PID RAS PATHWAY | Regulation of Ras family activation |
0.0 | 6.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.1 | 6.2 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
0.1 | 5.4 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.1 | 5.0 | PID MYC PATHWAY | C-MYC pathway |
0.0 | 4.7 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
0.1 | 4.6 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 4.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 14.5 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.2 | 12.4 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 7.2 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
0.0 | 7.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
0.1 | 6.3 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.1 | 6.0 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.2 | 5.8 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.1 | 5.6 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
0.2 | 4.8 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
0.1 | 4.6 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |