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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PAX4

Z-value: 0.56

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Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
PAX4
ENSG00000106331.17 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg38_v1_chr7_-_127618137_127618145-0.186.6e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_101237009 0.88 ENST00000305352.7
S1PR1
sphingosine-1-phosphate receptor 1
chr18_+_31447732 0.46 ENST00000257189.5
DSG3
desmoglein 3
chr8_+_32548267 0.44 ENST00000356819.7
NRG1
neuregulin 1
chr8_+_32548303 0.42 ENST00000650967.1
NRG1
neuregulin 1
chr8_+_32548210 0.41 ENST00000523079.5
ENST00000650919.1
NRG1
neuregulin 1
chr18_+_63587297 0.36 ENST00000269489.9
SERPINB13
serpin family B member 13
chr3_+_112086335 0.36 ENST00000431717.6
ENST00000480282.5
C3orf52
chromosome 3 open reading frame 52
chr18_+_63587336 0.35 ENST00000344731.10
SERPINB13
serpin family B member 13
chr1_+_15153698 0.34 ENST00000400796.7
ENST00000376008.3
ENST00000434578.6
TMEM51
transmembrane protein 51
chr3_+_112086364 0.32 ENST00000264848.10
C3orf52
chromosome 3 open reading frame 52
chr6_-_32838727 0.30 ENST00000652259.1
ENST00000374897.4
ENST00000620123.4
ENST00000452392.2
TAP2
ENSG00000250264.1
transporter 2, ATP binding cassette subfamily B member
novel protein, TAP2-HLA-DOB readthrough
chr22_-_39244969 0.30 ENST00000331163.11
PDGFB
platelet derived growth factor subunit B
chr13_+_32315071 0.28 ENST00000544455.6
BRCA2
BRCA2 DNA repair associated
chr7_+_26152188 0.27 ENST00000056233.4
NFE2L3
nuclear factor, erythroid 2 like 3
chr12_-_94650506 0.26 ENST00000261226.9
TMCC3
transmembrane and coiled-coil domain family 3
chr2_-_121285194 0.25 ENST00000263707.6
TFCP2L1
transcription factor CP2 like 1
chr2_+_102355750 0.25 ENST00000233957.7
IL18R1
interleukin 18 receptor 1
chr2_+_102355881 0.24 ENST00000409599.5
IL18R1
interleukin 18 receptor 1
chr6_+_29301701 0.23 ENST00000641895.1
OR14J1
olfactory receptor family 14 subfamily J member 1
chr11_+_72114840 0.22 ENST00000622388.4
FOLR3
folate receptor gamma
chr1_+_152908538 0.22 ENST00000368764.4
IVL
involucrin
chr13_-_24922788 0.21 ENST00000381884.9
CENPJ
centromere protein J
chr19_-_35900532 0.21 ENST00000396901.5
ENST00000641389.2
ENST00000585925.7
NFKBID
NFKB inhibitor delta
chr3_-_123620496 0.20 ENST00000578202.1
MYLK
myosin light chain kinase
chr8_+_142700095 0.20 ENST00000292430.10
ENST00000518841.5
ENST00000519387.1
LY6K
lymphocyte antigen 6 family member K
chr3_-_123620571 0.20 ENST00000583087.5
MYLK
myosin light chain kinase
chr8_-_133297092 0.20 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
NDRG1
N-myc downstream regulated 1
chr6_+_15246054 0.19 ENST00000341776.7
JARID2
jumonji and AT-rich interaction domain containing 2
chr8_+_142700465 0.18 ENST00000522591.1
LY6K
lymphocyte antigen 6 family member K
chr16_-_84239750 0.18 ENST00000568181.1
KCNG4
potassium voltage-gated channel modifier subfamily G member 4
chr6_+_32439866 0.17 ENST00000374982.5
ENST00000395388.7
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr9_+_131228109 0.17 ENST00000498010.2
ENST00000476004.5
ENST00000528406.1
NUP214
nucleoporin 214
chr18_-_55422492 0.16 ENST00000561992.5
ENST00000630712.2
TCF4
transcription factor 4
chr7_-_16833411 0.16 ENST00000412973.1
AGR2
anterior gradient 2, protein disulphide isomerase family member
chr4_+_47485268 0.16 ENST00000273859.8
ENST00000504445.1
ATP10D
ATPase phospholipid transporting 10D (putative)
chr7_-_127252919 0.16 ENST00000339582.7
GRM8
glutamate metabotropic receptor 8
chr12_-_13095664 0.16 ENST00000337630.10
ENST00000545699.1
GSG1
germ cell associated 1
chrM_+_5824 0.16 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr12_+_121743623 0.15 ENST00000541467.1
TMEM120B
transmembrane protein 120B
chr1_+_209827964 0.15 ENST00000491415.7
UTP25
UTP25 small subunit processor component
chr21_+_42513834 0.15 ENST00000352133.3
SLC37A1
solute carrier family 37 member 1
chr11_-_111871271 0.14 ENST00000398006.6
ALG9
ALG9 alpha-1,2-mannosyltransferase
chr18_-_55422306 0.14 ENST00000566777.5
ENST00000626584.2
TCF4
transcription factor 4
chr17_-_79009731 0.14 ENST00000392446.10
ENST00000590370.5
ENST00000591625.5
CANT1
calcium activated nucleotidase 1
chr1_-_247760556 0.14 ENST00000641256.1
OR1C1
olfactory receptor family 1 subfamily C member 1
chr8_-_126557691 0.13 ENST00000652209.1
LRATD2
LRAT domain containing 2
chr17_+_75093287 0.13 ENST00000538213.6
ENST00000584118.1
SLC16A5
solute carrier family 16 member 5
chr3_+_130850585 0.13 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATP2C1
ATPase secretory pathway Ca2+ transporting 1
chr1_-_228406761 0.13 ENST00000366699.3
ENST00000284551.11
TRIM11
tripartite motif containing 11
chr6_+_26500296 0.13 ENST00000684113.1
BTN1A1
butyrophilin subfamily 1 member A1
chrX_+_66164340 0.13 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
HEPH
hephaestin
chr12_-_120325936 0.13 ENST00000549767.1
PLA2G1B
phospholipase A2 group IB
chr5_+_147878703 0.13 ENST00000296694.5
SCGB3A2
secretoglobin family 3A member 2
chr19_-_9107475 0.13 ENST00000641081.1
OR7G2
olfactory receptor family 7 subfamily G member 2
chr11_-_111871530 0.13 ENST00000614444.4
ENST00000616540.5
ALG9
ALG9 alpha-1,2-mannosyltransferase
chrX_+_71910818 0.13 ENST00000633930.1
NHSL2
NHS like 2
chr17_-_48722510 0.12 ENST00000290294.5
PRAC1
PRAC1 small nuclear protein
chr5_-_16916400 0.12 ENST00000513882.5
MYO10
myosin X
chr17_-_79009778 0.12 ENST00000591773.5
ENST00000588611.5
ENST00000586916.6
ENST00000592033.5
ENST00000588075.5
ENST00000302345.6
ENST00000591811.1
CANT1
calcium activated nucleotidase 1
chr19_+_14941489 0.12 ENST00000248072.3
OR7C2
olfactory receptor family 7 subfamily C member 2
chr3_-_79767987 0.12 ENST00000464233.6
ROBO1
roundabout guidance receptor 1
chr1_-_151059561 0.12 ENST00000357235.6
ENST00000540998.5
CDC42SE1
CDC42 small effector 1
chr16_-_17470953 0.12 ENST00000261381.7
XYLT1
xylosyltransferase 1
chr5_-_43515128 0.12 ENST00000306862.7
C5orf34
chromosome 5 open reading frame 34
chr11_+_62123991 0.12 ENST00000533896.5
ENST00000278849.4
ENST00000394818.8
INCENP
inner centromere protein
chr9_+_27109393 0.11 ENST00000406359.8
TEK
TEK receptor tyrosine kinase
chr19_+_49119531 0.11 ENST00000334186.9
PPFIA3
PTPRF interacting protein alpha 3
chr2_+_191276885 0.11 ENST00000392316.5
MYO1B
myosin IB
chr16_-_28609992 0.11 ENST00000314752.11
SULT1A1
sulfotransferase family 1A member 1
chr12_+_78036248 0.11 ENST00000644176.1
NAV3
neuron navigator 3
chr7_-_140398456 0.11 ENST00000340308.7
ENST00000447932.6
ENST00000326232.14
ENST00000469193.5
SLC37A3
solute carrier family 37 member 3
chr19_-_49119092 0.11 ENST00000408991.4
C19orf73
chromosome 19 open reading frame 73
chr4_+_139665768 0.11 ENST00000616265.4
ENST00000265498.6
ENST00000506797.5
MGST2
microsomal glutathione S-transferase 2
chr19_+_49388243 0.11 ENST00000447857.8
KASH5
KASH domain containing 5
chrX_-_31266925 0.10 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
DMD
dystrophin
chrX_-_31178220 0.10 ENST00000681026.1
DMD
dystrophin
chrX_-_31178149 0.10 ENST00000679437.1
DMD
dystrophin
chr17_-_17577440 0.09 ENST00000395782.5
PEMT
phosphatidylethanolamine N-methyltransferase
chr5_+_127649018 0.09 ENST00000379445.7
CTXN3
cortexin 3
chr19_+_13023958 0.09 ENST00000587760.5
ENST00000585575.5
NFIX
nuclear factor I X
chr11_-_114595750 0.09 ENST00000424261.6
NXPE4
neurexophilin and PC-esterase domain family member 4
chr4_+_499194 0.09 ENST00000453061.7
ENST00000310340.9
ENST00000504346.5
ENST00000503111.5
ENST00000383028.8
ENST00000509768.1
PIGG
phosphatidylinositol glycan anchor biosynthesis class G
chr11_-_114595777 0.09 ENST00000375478.4
NXPE4
neurexophilin and PC-esterase domain family member 4
chr2_-_207624551 0.09 ENST00000272839.7
ENST00000426075.5
METTL21A
methyltransferase like 21A
chr18_-_55588535 0.09 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
TCF4
transcription factor 4
chr6_+_55174508 0.08 ENST00000370862.4
HCRTR2
hypocretin receptor 2
chr1_+_172420681 0.08 ENST00000367727.9
C1orf105
chromosome 1 open reading frame 105
chr1_+_22563460 0.08 ENST00000166244.8
ENST00000374644.8
EPHA8
EPH receptor A8
chr4_-_120066777 0.08 ENST00000296509.11
MAD2L1
mitotic arrest deficient 2 like 1
chr1_-_204494752 0.08 ENST00000684373.1
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chrX_+_135985416 0.08 ENST00000370698.7
ENST00000627534.2
ENST00000370695.8
ENST00000630721.3
ENST00000678163.1
SLC9A6
solute carrier family 9 member A6
chr7_+_80638633 0.08 ENST00000447544.7
ENST00000482059.6
CD36
CD36 molecule
chr7_-_130440848 0.08 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
CEP41
centrosomal protein 41
chr12_-_56752366 0.08 ENST00000672280.1
PRIM1
DNA primase subunit 1
chr1_+_15476099 0.08 ENST00000375910.8
CELA2B
chymotrypsin like elastase 2B
chr12_-_56752311 0.08 ENST00000338193.11
ENST00000550770.1
PRIM1
DNA primase subunit 1
chr3_+_46242453 0.07 ENST00000452454.1
ENST00000395940.3
ENST00000457243.1
CCR3
C-C motif chemokine receptor 3
chr18_-_55588184 0.07 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
TCF4
transcription factor 4
chr6_+_34889228 0.07 ENST00000360359.5
ENST00000649117.1
ENST00000650178.1
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr9_-_137070548 0.07 ENST00000409687.5
SAPCD2
suppressor APC domain containing 2
chr6_-_105179952 0.07 ENST00000254765.4
POPDC3
popeye domain containing 3
chr3_+_119579676 0.07 ENST00000357003.7
ADPRH
ADP-ribosylarginine hydrolase
chr2_-_24328113 0.07 ENST00000622089.4
ITSN2
intersectin 2
chr2_+_99141696 0.07 ENST00000650052.2
ENST00000409684.2
C2orf15
chromosome 2 open reading frame 15
chr10_+_72893734 0.07 ENST00000334011.10
OIT3
oncoprotein induced transcript 3
chr11_-_62601223 0.07 ENST00000527204.5
MTA2
metastasis associated 1 family member 2
chr6_-_10694533 0.07 ENST00000460742.6
ENST00000379586.5
ENST00000259983.8
C6orf52
chromosome 6 open reading frame 52
chr2_+_203014842 0.07 ENST00000683969.1
ENST00000449802.5
NBEAL1
neurobeachin like 1
chr3_+_46242371 0.07 ENST00000545097.1
CCR3
C-C motif chemokine receptor 3
chr11_+_26332117 0.07 ENST00000531646.1
ENST00000256737.8
ANO3
anoctamin 3
chr12_-_44875647 0.07 ENST00000395487.6
NELL2
neural EGFL like 2
chr1_-_24964984 0.06 ENST00000338888.3
ENST00000399916.5
RUNX3
RUNX family transcription factor 3
chr1_-_85276467 0.06 ENST00000648566.1
BCL10
BCL10 immune signaling adaptor
chrX_+_47145240 0.06 ENST00000628161.2
ENST00000345781.10
RBM10
RNA binding motif protein 10
chr8_+_103880412 0.06 ENST00000436393.6
RIMS2
regulating synaptic membrane exocytosis 2
chr11_-_124752187 0.06 ENST00000403470.1
VSIG2
V-set and immunoglobulin domain containing 2
chr11_-_59212869 0.06 ENST00000361050.4
MPEG1
macrophage expressed 1
chr6_+_110982028 0.06 ENST00000441448.7
RPF2
ribosome production factor 2 homolog
chrX_+_30235894 0.06 ENST00000620842.1
MAGEB3
MAGE family member B3
chr18_-_46964408 0.06 ENST00000676383.1
ENSG00000288616.1
elongin A3 family member D
chr17_+_74274241 0.06 ENST00000582036.5
DNAI2
dynein axonemal intermediate chain 2
chr2_-_136118142 0.06 ENST00000241393.4
CXCR4
C-X-C motif chemokine receptor 4
chr10_-_69573416 0.06 ENST00000242462.5
NEUROG3
neurogenin 3
chr8_-_673547 0.06 ENST00000522893.1
ERICH1
glutamate rich 1
chr12_-_117968223 0.05 ENST00000425217.5
KSR2
kinase suppressor of ras 2
chr11_+_123902167 0.05 ENST00000641687.1
OR8D4
olfactory receptor family 8 subfamily D member 4
chr6_-_116668751 0.05 ENST00000368576.8
ENST00000368573.5
ZUP1
zinc finger containing ubiquitin peptidase 1
chr19_+_38289138 0.05 ENST00000590738.1
ENST00000587519.4
ENST00000591889.2
SPINT2
ENSG00000267748.4
serine peptidase inhibitor, Kunitz type 2
novel protein
chr9_+_127803208 0.05 ENST00000373225.7
ENST00000431857.5
FPGS
folylpolyglutamate synthase
chr11_+_120236635 0.05 ENST00000260264.8
POU2F3
POU class 2 homeobox 3
chr9_+_27109135 0.05 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr3_-_197749688 0.05 ENST00000273582.9
RUBCN
rubicon autophagy regulator
chr21_-_32279012 0.05 ENST00000290130.4
MIS18A
MIS18 kinetochore protein A
chr7_+_100884974 0.05 ENST00000448764.5
SRRT
serrate, RNA effector molecule
chr8_-_73293616 0.05 ENST00000352983.7
ENST00000396467.5
RPL7
ribosomal protein L7
chr4_+_164754116 0.05 ENST00000507311.1
SMIM31
small integral membrane protein 31
chr7_+_73433761 0.05 ENST00000344575.5
FZD9
frizzled class receptor 9
chr2_-_136116165 0.05 ENST00000409817.1
CXCR4
C-X-C motif chemokine receptor 4
chr20_-_46364385 0.05 ENST00000243896.6
ENST00000543605.5
ENST00000372230.10
ENST00000317734.12
SLC35C2
solute carrier family 35 member C2
chrX_-_31266857 0.05 ENST00000378702.8
ENST00000361471.8
DMD
dystrophin
chrX_+_47145200 0.05 ENST00000377604.8
RBM10
RNA binding motif protein 10
chr6_-_32128191 0.05 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
ATF6B
activating transcription factor 6 beta
chr4_+_94207845 0.05 ENST00000457823.6
ENST00000354268.9
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr7_-_130441136 0.05 ENST00000675596.1
ENST00000676312.1
CEP41
centrosomal protein 41
chr2_+_203014721 0.04 ENST00000683091.1
NBEAL1
neurobeachin like 1
chr6_+_10694916 0.04 ENST00000379568.4
PAK1IP1
PAK1 interacting protein 1
chrM_+_8489 0.04 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase membrane subunit 6
chr11_+_46719193 0.04 ENST00000311907.10
ENST00000530231.5
ENST00000442468.1
F2
coagulation factor II, thrombin
chr18_-_3874247 0.04 ENST00000581699.5
DLGAP1
DLG associated protein 1
chr10_+_112375196 0.04 ENST00000393081.6
ACSL5
acyl-CoA synthetase long chain family member 5
chr1_-_201171545 0.04 ENST00000367333.6
TMEM9
transmembrane protein 9
chr10_-_68232108 0.04 ENST00000373673.5
ATOH7
atonal bHLH transcription factor 7
chr2_-_150487658 0.04 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
RND3
Rho family GTPase 3
chr3_+_186666003 0.04 ENST00000232003.5
HRG
histidine rich glycoprotein
chr6_+_31615215 0.04 ENST00000337917.11
ENST00000376059.8
AIF1
allograft inflammatory factor 1
chr1_-_231241090 0.04 ENST00000451322.1
C1orf131
chromosome 1 open reading frame 131
chr1_-_231241121 0.04 ENST00000318906.6
ENST00000366649.7
ENST00000366651.7
C1orf131
chromosome 1 open reading frame 131
chr13_+_36674013 0.04 ENST00000315190.4
SERTM1
serine rich and transmembrane domain containing 1
chr9_+_27109200 0.04 ENST00000380036.10
TEK
TEK receptor tyrosine kinase
chr1_-_37690481 0.04 ENST00000464085.5
ENST00000358011.8
ENST00000461359.5
ENST00000486637.2
C1orf109
chromosome 1 open reading frame 109
chr5_+_144205250 0.04 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr16_-_28597042 0.04 ENST00000533150.5
ENST00000335715.9
SULT1A2
sulfotransferase family 1A member 2
chr4_+_169620527 0.04 ENST00000360642.7
ENST00000512813.5
ENST00000513761.6
CLCN3
chloride voltage-gated channel 3
chr18_+_32190033 0.04 ENST00000269202.11
MEP1B
meprin A subunit beta
chr7_-_86965872 0.04 ENST00000398276.6
ENST00000416314.5
ENST00000425689.1
ELAPOR2
endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr4_-_170090153 0.04 ENST00000509167.5
ENST00000353187.6
ENST00000507375.5
ENST00000515480.5
AADAT
aminoadipate aminotransferase
chr11_+_57761787 0.04 ENST00000358694.10
ENST00000361332.8
ENST00000361391.10
ENST00000361796.9
ENST00000415361.6
ENST00000426142.6
ENST00000428599.6
ENST00000525902.5
ENST00000526357.5
ENST00000526772.5
ENST00000527467.5
ENST00000528232.5
ENST00000528621.5
ENST00000529526.5
ENST00000529873.5
ENST00000529986.5
ENST00000530094.5
ENST00000530748.5
ENST00000531014.5
ENST00000532245.5
ENST00000532463.5
ENST00000532649.5
ENST00000532787.5
ENST00000532844.5
ENST00000533667.5
ENST00000534579.5
ENST00000399050.10
ENST00000526938.5
ENST00000674015.1
ENST00000531007.2
ENST00000673826.1
CTNND1
catenin delta 1
chr17_+_48723179 0.03 ENST00000422730.4
PRAC2
PRAC2 small nuclear protein
chr1_-_244862381 0.03 ENST00000640001.1
ENST00000639628.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U
chr12_-_113136224 0.03 ENST00000546530.5
ENST00000261729.9
RASAL1
RAS protein activator like 1
chr7_+_134127299 0.03 ENST00000645682.1
ENST00000285928.2
LRGUK
leucine rich repeats and guanylate kinase domain containing
chr18_+_32190015 0.03 ENST00000581447.1
MEP1B
meprin A subunit beta
chr5_-_59586393 0.03 ENST00000505453.1
ENST00000360047.9
PDE4D
phosphodiesterase 4D
chr12_-_113135710 0.03 ENST00000446861.7
RASAL1
RAS protein activator like 1
chr2_+_106487349 0.03 ENST00000643224.2
ENST00000416057.2
CD8B2
CD8b2 molecule
chr16_-_28609976 0.03 ENST00000566189.5
SULT1A1
sulfotransferase family 1A member 1
chr16_+_67570741 0.03 ENST00000644753.1
ENST00000642819.1
ENST00000645306.1
CTCF
CCCTC-binding factor
chr19_+_10013468 0.03 ENST00000591589.3
RDH8
retinol dehydrogenase 8
chr10_+_6144883 0.03 ENST00000379789.8
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr16_+_69924984 0.03 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr2_+_69013379 0.03 ENST00000409349.7
ANTXR1
ANTXR cell adhesion molecule 1
chr5_-_133968578 0.03 ENST00000231512.5
C5orf15
chromosome 5 open reading frame 15
chr11_-_35420017 0.03 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
SLC1A2
solute carrier family 1 member 2
chr19_+_9250930 0.03 ENST00000456448.3
OR7E24
olfactory receptor family 7 subfamily E member 24
chr13_-_46897021 0.03 ENST00000542664.4
ENST00000543956.5
HTR2A
5-hydroxytryptamine receptor 2A
chrX_-_132413597 0.03 ENST00000394311.6
MBNL3
muscleblind like splicing regulator 3
chr4_-_169010080 0.02 ENST00000504561.1
CBR4
carbonyl reductase 4
chr4_+_169620509 0.02 ENST00000347613.8
CLCN3
chloride voltage-gated channel 3
chr11_-_35420050 0.02 ENST00000395753.6
ENST00000395750.6
ENST00000645634.1
SLC1A2
solute carrier family 1 member 2
chr3_-_128153782 0.02 ENST00000464873.5
RUVBL1
RuvB like AAA ATPase 1
chr2_-_216694794 0.02 ENST00000449583.1
IGFBP5
insulin like growth factor binding protein 5
chr17_-_74893622 0.02 ENST00000612771.5
ENST00000621859.1
FADS6
fatty acid desaturase 6
chr6_+_20403679 0.02 ENST00000535432.2
E2F3
E2F transcription factor 3
chr1_+_26317950 0.02 ENST00000374213.3
CD52
CD52 molecule
chr8_+_11809135 0.02 ENST00000528643.5
ENST00000525777.5
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr1_+_21551260 0.02 ENST00000374832.5
ALPL
alkaline phosphatase, biomineralization associated
chrX_-_154295085 0.02 ENST00000617225.4
ENST00000619903.4
TEX28
testis expressed 28
chr11_-_35419098 0.02 ENST00000606205.6
ENST00000645303.1
SLC1A2
solute carrier family 1 member 2
chr2_-_169694367 0.02 ENST00000447353.6
CCDC173
coiled-coil domain containing 173
chr2_+_15591164 0.02 ENST00000381341.7
DDX1
DEAD-box helicase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0046967 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) cytosol to ER transport(GO:0046967)
0.1 0.3 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 1.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.5 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.1 0.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.5 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0061511 centriole elongation(GO:0061511)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.3 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.1 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.0 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 1.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.9 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC