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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PAX4

Z-value: 0.56

Motif logo

Transcription factors associated with PAX4

Gene Symbol Gene ID Gene Info
ENSG00000106331.17 paired box 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX4hg38_v1_chr7_-_127618137_127618145-0.186.6e-01Click!

Activity profile of PAX4 motif

Sorted Z-values of PAX4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_101237009 0.88 ENST00000305352.7
sphingosine-1-phosphate receptor 1
chr18_+_31447732 0.46 ENST00000257189.5
desmoglein 3
chr8_+_32548267 0.44 ENST00000356819.7
neuregulin 1
chr8_+_32548303 0.42 ENST00000650967.1
neuregulin 1
chr8_+_32548210 0.41 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr18_+_63587297 0.36 ENST00000269489.9
serpin family B member 13
chr3_+_112086335 0.36 ENST00000431717.6
ENST00000480282.5
chromosome 3 open reading frame 52
chr18_+_63587336 0.35 ENST00000344731.10
serpin family B member 13
chr1_+_15153698 0.34 ENST00000400796.7
ENST00000376008.3
ENST00000434578.6
transmembrane protein 51
chr3_+_112086364 0.32 ENST00000264848.10
chromosome 3 open reading frame 52
chr6_-_32838727 0.30 ENST00000652259.1
ENST00000374897.4
ENST00000620123.4
ENST00000452392.2
transporter 2, ATP binding cassette subfamily B member
novel protein, TAP2-HLA-DOB readthrough
chr22_-_39244969 0.30 ENST00000331163.11
platelet derived growth factor subunit B
chr13_+_32315071 0.28 ENST00000544455.6
BRCA2 DNA repair associated
chr7_+_26152188 0.27 ENST00000056233.4
nuclear factor, erythroid 2 like 3
chr12_-_94650506 0.26 ENST00000261226.9
transmembrane and coiled-coil domain family 3
chr2_-_121285194 0.25 ENST00000263707.6
transcription factor CP2 like 1
chr2_+_102355750 0.25 ENST00000233957.7
interleukin 18 receptor 1
chr2_+_102355881 0.24 ENST00000409599.5
interleukin 18 receptor 1
chr6_+_29301701 0.23 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr11_+_72114840 0.22 ENST00000622388.4
folate receptor gamma
chr1_+_152908538 0.22 ENST00000368764.4
involucrin
chr13_-_24922788 0.21 ENST00000381884.9
centromere protein J
chr19_-_35900532 0.21 ENST00000396901.5
ENST00000641389.2
ENST00000585925.7
NFKB inhibitor delta
chr3_-_123620496 0.20 ENST00000578202.1
myosin light chain kinase
chr8_+_142700095 0.20 ENST00000292430.10
ENST00000518841.5
ENST00000519387.1
lymphocyte antigen 6 family member K
chr3_-_123620571 0.20 ENST00000583087.5
myosin light chain kinase
chr8_-_133297092 0.20 ENST00000522890.5
ENST00000675983.1
ENST00000518176.5
ENST00000323851.13
ENST00000522476.5
ENST00000518066.5
ENST00000521544.5
ENST00000674605.1
ENST00000518480.5
ENST00000523892.5
N-myc downstream regulated 1
chr6_+_15246054 0.19 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr8_+_142700465 0.18 ENST00000522591.1
lymphocyte antigen 6 family member K
chr16_-_84239750 0.18 ENST00000568181.1
potassium voltage-gated channel modifier subfamily G member 4
chr6_+_32439866 0.17 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr9_+_131228109 0.17 ENST00000498010.2
ENST00000476004.5
ENST00000528406.1
nucleoporin 214
chr18_-_55422492 0.16 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr7_-_16833411 0.16 ENST00000412973.1
anterior gradient 2, protein disulphide isomerase family member
chr4_+_47485268 0.16 ENST00000273859.8
ENST00000504445.1
ATPase phospholipid transporting 10D (putative)
chr7_-_127252919 0.16 ENST00000339582.7
glutamate metabotropic receptor 8
chr12_-_13095664 0.16 ENST00000337630.10
ENST00000545699.1
germ cell associated 1
chrM_+_5824 0.16 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr12_+_121743623 0.15 ENST00000541467.1
transmembrane protein 120B
chr1_+_209827964 0.15 ENST00000491415.7
UTP25 small subunit processor component
chr21_+_42513834 0.15 ENST00000352133.3
solute carrier family 37 member 1
chr11_-_111871271 0.14 ENST00000398006.6
ALG9 alpha-1,2-mannosyltransferase
chr18_-_55422306 0.14 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr17_-_79009731 0.14 ENST00000392446.10
ENST00000590370.5
ENST00000591625.5
calcium activated nucleotidase 1
chr1_-_247760556 0.14 ENST00000641256.1
olfactory receptor family 1 subfamily C member 1
chr8_-_126557691 0.13 ENST00000652209.1
LRAT domain containing 2
chr17_+_75093287 0.13 ENST00000538213.6
ENST00000584118.1
solute carrier family 16 member 5
chr3_+_130850585 0.13 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr1_-_228406761 0.13 ENST00000366699.3
ENST00000284551.11
tripartite motif containing 11
chr6_+_26500296 0.13 ENST00000684113.1
butyrophilin subfamily 1 member A1
chrX_+_66164340 0.13 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
hephaestin
chr12_-_120325936 0.13 ENST00000549767.1
phospholipase A2 group IB
chr5_+_147878703 0.13 ENST00000296694.5
secretoglobin family 3A member 2
chr19_-_9107475 0.13 ENST00000641081.1
olfactory receptor family 7 subfamily G member 2
chr11_-_111871530 0.13 ENST00000614444.4
ENST00000616540.5
ALG9 alpha-1,2-mannosyltransferase
chrX_+_71910818 0.13 ENST00000633930.1
NHS like 2
chr17_-_48722510 0.12 ENST00000290294.5
PRAC1 small nuclear protein
chr5_-_16916400 0.12 ENST00000513882.5
myosin X
chr17_-_79009778 0.12 ENST00000591773.5
ENST00000588611.5
ENST00000586916.6
ENST00000592033.5
ENST00000588075.5
ENST00000302345.6
ENST00000591811.1
calcium activated nucleotidase 1
chr19_+_14941489 0.12 ENST00000248072.3
olfactory receptor family 7 subfamily C member 2
chr3_-_79767987 0.12 ENST00000464233.6
roundabout guidance receptor 1
chr1_-_151059561 0.12 ENST00000357235.6
ENST00000540998.5
CDC42 small effector 1
chr16_-_17470953 0.12 ENST00000261381.7
xylosyltransferase 1
chr5_-_43515128 0.12 ENST00000306862.7
chromosome 5 open reading frame 34
chr11_+_62123991 0.12 ENST00000533896.5
ENST00000278849.4
ENST00000394818.8
inner centromere protein
chr9_+_27109393 0.11 ENST00000406359.8
TEK receptor tyrosine kinase
chr19_+_49119531 0.11 ENST00000334186.9
PTPRF interacting protein alpha 3
chr2_+_191276885 0.11 ENST00000392316.5
myosin IB
chr16_-_28609992 0.11 ENST00000314752.11
sulfotransferase family 1A member 1
chr12_+_78036248 0.11 ENST00000644176.1
neuron navigator 3
chr7_-_140398456 0.11 ENST00000340308.7
ENST00000447932.6
ENST00000326232.14
ENST00000469193.5
solute carrier family 37 member 3
chr19_-_49119092 0.11 ENST00000408991.4
chromosome 19 open reading frame 73
chr4_+_139665768 0.11 ENST00000616265.4
ENST00000265498.6
ENST00000506797.5
microsomal glutathione S-transferase 2
chr19_+_49388243 0.11 ENST00000447857.8
KASH domain containing 5
chrX_-_31266925 0.10 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
dystrophin
chrX_-_31178220 0.10 ENST00000681026.1
dystrophin
chrX_-_31178149 0.10 ENST00000679437.1
dystrophin
chr17_-_17577440 0.09 ENST00000395782.5
phosphatidylethanolamine N-methyltransferase
chr5_+_127649018 0.09 ENST00000379445.7
cortexin 3
chr19_+_13023958 0.09 ENST00000587760.5
ENST00000585575.5
nuclear factor I X
chr11_-_114595750 0.09 ENST00000424261.6
neurexophilin and PC-esterase domain family member 4
chr4_+_499194 0.09 ENST00000453061.7
ENST00000310340.9
ENST00000504346.5
ENST00000503111.5
ENST00000383028.8
ENST00000509768.1
phosphatidylinositol glycan anchor biosynthesis class G
chr11_-_114595777 0.09 ENST00000375478.4
neurexophilin and PC-esterase domain family member 4
chr2_-_207624551 0.09 ENST00000272839.7
ENST00000426075.5
methyltransferase like 21A
chr18_-_55588535 0.09 ENST00000566286.5
ENST00000566279.5
ENST00000626595.2
ENST00000564999.5
ENST00000616053.4
ENST00000356073.8
transcription factor 4
chr6_+_55174508 0.08 ENST00000370862.4
hypocretin receptor 2
chr1_+_172420681 0.08 ENST00000367727.9
chromosome 1 open reading frame 105
chr1_+_22563460 0.08 ENST00000166244.8
ENST00000374644.8
EPH receptor A8
chr4_-_120066777 0.08 ENST00000296509.11
mitotic arrest deficient 2 like 1
chr1_-_204494752 0.08 ENST00000684373.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
chrX_+_135985416 0.08 ENST00000370698.7
ENST00000627534.2
ENST00000370695.8
ENST00000630721.3
ENST00000678163.1
solute carrier family 9 member A6
chr7_+_80638633 0.08 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr7_-_130440848 0.08 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
centrosomal protein 41
chr12_-_56752366 0.08 ENST00000672280.1
DNA primase subunit 1
chr1_+_15476099 0.08 ENST00000375910.8
chymotrypsin like elastase 2B
chr12_-_56752311 0.08 ENST00000338193.11
ENST00000550770.1
DNA primase subunit 1
chr3_+_46242453 0.07 ENST00000452454.1
ENST00000395940.3
ENST00000457243.1
C-C motif chemokine receptor 3
chr18_-_55588184 0.07 ENST00000354452.8
ENST00000565908.6
ENST00000635822.2
transcription factor 4
chr6_+_34889228 0.07 ENST00000360359.5
ENST00000649117.1
ENST00000650178.1
ankyrin repeat and sterile alpha motif domain containing 1A
chr9_-_137070548 0.07 ENST00000409687.5
suppressor APC domain containing 2
chr6_-_105179952 0.07 ENST00000254765.4
popeye domain containing 3
chr3_+_119579676 0.07 ENST00000357003.7
ADP-ribosylarginine hydrolase
chr2_-_24328113 0.07 ENST00000622089.4
intersectin 2
chr2_+_99141696 0.07 ENST00000650052.2
ENST00000409684.2
chromosome 2 open reading frame 15
chr10_+_72893734 0.07 ENST00000334011.10
oncoprotein induced transcript 3
chr11_-_62601223 0.07 ENST00000527204.5
metastasis associated 1 family member 2
chr6_-_10694533 0.07 ENST00000460742.6
ENST00000379586.5
ENST00000259983.8
chromosome 6 open reading frame 52
chr2_+_203014842 0.07 ENST00000683969.1
ENST00000449802.5
neurobeachin like 1
chr3_+_46242371 0.07 ENST00000545097.1
C-C motif chemokine receptor 3
chr11_+_26332117 0.07 ENST00000531646.1
ENST00000256737.8
anoctamin 3
chr12_-_44875647 0.07 ENST00000395487.6
neural EGFL like 2
chr1_-_24964984 0.06 ENST00000338888.3
ENST00000399916.5
RUNX family transcription factor 3
chr1_-_85276467 0.06 ENST00000648566.1
BCL10 immune signaling adaptor
chrX_+_47145240 0.06 ENST00000628161.2
ENST00000345781.10
RNA binding motif protein 10
chr8_+_103880412 0.06 ENST00000436393.6
regulating synaptic membrane exocytosis 2
chr11_-_124752187 0.06 ENST00000403470.1
V-set and immunoglobulin domain containing 2
chr11_-_59212869 0.06 ENST00000361050.4
macrophage expressed 1
chr6_+_110982028 0.06 ENST00000441448.7
ribosome production factor 2 homolog
chrX_+_30235894 0.06 ENST00000620842.1
MAGE family member B3
chr18_-_46964408 0.06 ENST00000676383.1
elongin A3 family member D
chr17_+_74274241 0.06 ENST00000582036.5
dynein axonemal intermediate chain 2
chr2_-_136118142 0.06 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr10_-_69573416 0.06 ENST00000242462.5
neurogenin 3
chr8_-_673547 0.06 ENST00000522893.1
glutamate rich 1
chr12_-_117968223 0.05 ENST00000425217.5
kinase suppressor of ras 2
chr11_+_123902167 0.05 ENST00000641687.1
olfactory receptor family 8 subfamily D member 4
chr6_-_116668751 0.05 ENST00000368576.8
ENST00000368573.5
zinc finger containing ubiquitin peptidase 1
chr19_+_38289138 0.05 ENST00000590738.1
ENST00000587519.4
ENST00000591889.2
serine peptidase inhibitor, Kunitz type 2
novel protein
chr9_+_127803208 0.05 ENST00000373225.7
ENST00000431857.5
folylpolyglutamate synthase
chr11_+_120236635 0.05 ENST00000260264.8
POU class 2 homeobox 3
chr9_+_27109135 0.05 ENST00000519097.5
ENST00000615002.4
TEK receptor tyrosine kinase
chr3_-_197749688 0.05 ENST00000273582.9
rubicon autophagy regulator
chr21_-_32279012 0.05 ENST00000290130.4
MIS18 kinetochore protein A
chr7_+_100884974 0.05 ENST00000448764.5
serrate, RNA effector molecule
chr8_-_73293616 0.05 ENST00000352983.7
ENST00000396467.5
ribosomal protein L7
chr4_+_164754116 0.05 ENST00000507311.1
small integral membrane protein 31
chr7_+_73433761 0.05 ENST00000344575.5
frizzled class receptor 9
chr2_-_136116165 0.05 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr20_-_46364385 0.05 ENST00000243896.6
ENST00000543605.5
ENST00000372230.10
ENST00000317734.12
solute carrier family 35 member C2
chrX_-_31266857 0.05 ENST00000378702.8
ENST00000361471.8
dystrophin
chrX_+_47145200 0.05 ENST00000377604.8
RNA binding motif protein 10
chr6_-_32128191 0.05 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
activating transcription factor 6 beta
chr4_+_94207845 0.05 ENST00000457823.6
ENST00000354268.9
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr7_-_130441136 0.05 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr2_+_203014721 0.04 ENST00000683091.1
neurobeachin like 1
chr6_+_10694916 0.04 ENST00000379568.4
PAK1 interacting protein 1
chrM_+_8489 0.04 ENST00000361899.2
mitochondrially encoded ATP synthase membrane subunit 6
chr11_+_46719193 0.04 ENST00000311907.10
ENST00000530231.5
ENST00000442468.1
coagulation factor II, thrombin
chr18_-_3874247 0.04 ENST00000581699.5
DLG associated protein 1
chr10_+_112375196 0.04 ENST00000393081.6
acyl-CoA synthetase long chain family member 5
chr1_-_201171545 0.04 ENST00000367333.6
transmembrane protein 9
chr10_-_68232108 0.04 ENST00000373673.5
atonal bHLH transcription factor 7
chr2_-_150487658 0.04 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr3_+_186666003 0.04 ENST00000232003.5
histidine rich glycoprotein
chr6_+_31615215 0.04 ENST00000337917.11
ENST00000376059.8
allograft inflammatory factor 1
chr1_-_231241090 0.04 ENST00000451322.1
chromosome 1 open reading frame 131
chr1_-_231241121 0.04 ENST00000318906.6
ENST00000366649.7
ENST00000366651.7
chromosome 1 open reading frame 131
chr13_+_36674013 0.04 ENST00000315190.4
serine rich and transmembrane domain containing 1
chr9_+_27109200 0.04 ENST00000380036.10
TEK receptor tyrosine kinase
chr1_-_37690481 0.04 ENST00000464085.5
ENST00000358011.8
ENST00000461359.5
ENST00000486637.2
chromosome 1 open reading frame 109
chr5_+_144205250 0.04 ENST00000507359.3
potassium channel tetramerization domain containing 16
chr16_-_28597042 0.04 ENST00000533150.5
ENST00000335715.9
sulfotransferase family 1A member 2
chr4_+_169620527 0.04 ENST00000360642.7
ENST00000512813.5
ENST00000513761.6
chloride voltage-gated channel 3
chr18_+_32190033 0.04 ENST00000269202.11
meprin A subunit beta
chr7_-_86965872 0.04 ENST00000398276.6
ENST00000416314.5
ENST00000425689.1
endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr4_-_170090153 0.04 ENST00000509167.5
ENST00000353187.6
ENST00000507375.5
ENST00000515480.5
aminoadipate aminotransferase
chr11_+_57761787 0.04 ENST00000358694.10
ENST00000361332.8
ENST00000361391.10
ENST00000361796.9
ENST00000415361.6
ENST00000426142.6
ENST00000428599.6
ENST00000525902.5
ENST00000526357.5
ENST00000526772.5
ENST00000527467.5
ENST00000528232.5
ENST00000528621.5
ENST00000529526.5
ENST00000529873.5
ENST00000529986.5
ENST00000530094.5
ENST00000530748.5
ENST00000531014.5
ENST00000532245.5
ENST00000532463.5
ENST00000532649.5
ENST00000532787.5
ENST00000532844.5
ENST00000533667.5
ENST00000534579.5
ENST00000399050.10
ENST00000526938.5
ENST00000674015.1
ENST00000531007.2
ENST00000673826.1
catenin delta 1
chr17_+_48723179 0.03 ENST00000422730.4
PRAC2 small nuclear protein
chr1_-_244862381 0.03 ENST00000640001.1
ENST00000639628.1
heterogeneous nuclear ribonucleoprotein U
chr12_-_113136224 0.03 ENST00000546530.5
ENST00000261729.9
RAS protein activator like 1
chr7_+_134127299 0.03 ENST00000645682.1
ENST00000285928.2
leucine rich repeats and guanylate kinase domain containing
chr18_+_32190015 0.03 ENST00000581447.1
meprin A subunit beta
chr5_-_59586393 0.03 ENST00000505453.1
ENST00000360047.9
phosphodiesterase 4D
chr12_-_113135710 0.03 ENST00000446861.7
RAS protein activator like 1
chr2_+_106487349 0.03 ENST00000643224.2
ENST00000416057.2
CD8b2 molecule
chr16_-_28609976 0.03 ENST00000566189.5
sulfotransferase family 1A member 1
chr16_+_67570741 0.03 ENST00000644753.1
ENST00000642819.1
ENST00000645306.1
CCCTC-binding factor
chr19_+_10013468 0.03 ENST00000591589.3
retinol dehydrogenase 8
chr10_+_6144883 0.03 ENST00000379789.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr16_+_69924984 0.03 ENST00000568684.1
WW domain containing E3 ubiquitin protein ligase 2
chr2_+_69013379 0.03 ENST00000409349.7
ANTXR cell adhesion molecule 1
chr5_-_133968578 0.03 ENST00000231512.5
chromosome 5 open reading frame 15
chr11_-_35420017 0.03 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
solute carrier family 1 member 2
chr19_+_9250930 0.03 ENST00000456448.3
olfactory receptor family 7 subfamily E member 24
chr13_-_46897021 0.03 ENST00000542664.4
ENST00000543956.5
5-hydroxytryptamine receptor 2A
chrX_-_132413597 0.03 ENST00000394311.6
muscleblind like splicing regulator 3
chr4_-_169010080 0.02 ENST00000504561.1
carbonyl reductase 4
chr4_+_169620509 0.02 ENST00000347613.8
chloride voltage-gated channel 3
chr11_-_35420050 0.02 ENST00000395753.6
ENST00000395750.6
ENST00000645634.1
solute carrier family 1 member 2
chr3_-_128153782 0.02 ENST00000464873.5
RuvB like AAA ATPase 1
chr2_-_216694794 0.02 ENST00000449583.1
insulin like growth factor binding protein 5
chr17_-_74893622 0.02 ENST00000612771.5
ENST00000621859.1
fatty acid desaturase 6
chr6_+_20403679 0.02 ENST00000535432.2
E2F transcription factor 3
chr1_+_26317950 0.02 ENST00000374213.3
CD52 molecule
chr8_+_11809135 0.02 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr1_+_21551260 0.02 ENST00000374832.5
alkaline phosphatase, biomineralization associated
chrX_-_154295085 0.02 ENST00000617225.4
ENST00000619903.4
testis expressed 28
chr11_-_35419098 0.02 ENST00000606205.6
ENST00000645303.1
solute carrier family 1 member 2
chr2_-_169694367 0.02 ENST00000447353.6
coiled-coil domain containing 173
chr2_+_15591164 0.02 ENST00000381341.7
DEAD-box helicase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0046967 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) cytosol to ER transport(GO:0046967)
0.1 0.3 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 1.3 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.5 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.1 0.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.5 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.0 0.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:0061511 centriole elongation(GO:0061511)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.3 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.1 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.1 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.1 GO:1990742 microvesicle(GO:1990742)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.3 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.0 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 1.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.9 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 0.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC