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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PAX6

Z-value: 0.67

Motif logo

Transcription factors associated with PAX6

Gene Symbol Gene ID Gene Info
ENSG00000007372.24 paired box 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX6hg38_v1_chr11_-_31811314_31811336-0.531.7e-01Click!

Activity profile of PAX6 motif

Sorted Z-values of PAX6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_63752935 0.73 ENST00000425392.5
ENST00000336429.6
serpin family B member 7
chr2_-_160200310 0.69 ENST00000620391.4
integrin subunit beta 6
chr1_-_242449478 0.64 ENST00000427495.5
phospholipase D family member 5
chr2_-_160200251 0.64 ENST00000428609.6
ENST00000409967.6
ENST00000283249.7
integrin subunit beta 6
chr18_+_63777773 0.64 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr2_-_160200289 0.62 ENST00000409872.1
integrin subunit beta 6
chr11_-_88175432 0.53 ENST00000531138.1
ENST00000526372.1
ENST00000243662.11
RAB38, member RAS oncogene family
chr1_+_2073986 0.51 ENST00000461106.6
protein kinase C zeta
chr1_-_201399302 0.49 ENST00000633953.1
ENST00000391967.7
ladinin 1
chr4_+_76435216 0.48 ENST00000296043.7
shroom family member 3
chr4_+_40192949 0.47 ENST00000507851.5
ENST00000615577.4
ENST00000613272.4
ras homolog family member H
chrX_-_107206426 0.47 ENST00000372466.8
ENST00000421752.1
nucleoporin 62 C-terminal like
chr1_-_159945596 0.45 ENST00000361509.7
ENST00000611023.1
ENST00000368094.6
immunoglobulin superfamily member 9
chr1_-_201399525 0.44 ENST00000367313.4
ladinin 1
chr12_+_82686889 0.41 ENST00000321196.8
transmembrane O-mannosyltransferase targeting cadherins 2
chr3_-_125120813 0.40 ENST00000430155.6
solute carrier family 12 member 8
chr9_+_90827452 0.40 ENST00000375746.1
spleen associated tyrosine kinase
chr11_-_58575846 0.40 ENST00000395074.7
leupaxin
chr5_+_140875299 0.38 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr12_-_84912816 0.32 ENST00000680469.1
ENST00000450363.4
ENST00000681106.1
solute carrier family 6 member 15
chr17_-_41060109 0.32 ENST00000391418.3
keratin associated protein 2-3
chr16_+_71626175 0.31 ENST00000268485.8
ENST00000565261.1
ENST00000299952.4
MARVEL domain containing 3
chr14_+_61529005 0.28 ENST00000556347.1
novel protein
chr12_+_77830886 0.25 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr1_+_161707244 0.24 ENST00000349527.8
ENST00000294796.8
ENST00000309691.10
ENST00000367953.7
ENST00000367950.2
Fc receptor like A
chr5_+_136058849 0.24 ENST00000508076.5
transforming growth factor beta induced
chr11_+_60924452 0.23 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
transmembrane protein 132A
chr17_-_40867200 0.21 ENST00000647902.1
ENST00000251643.5
keratin 12
chr10_-_117005570 0.21 ENST00000260777.14
ENST00000392903.3
shootin 1
chr10_+_5196831 0.21 ENST00000263126.3
aldo-keto reductase family 1 member C4
chr19_+_49388243 0.21 ENST00000447857.8
KASH domain containing 5
chrX_+_107206632 0.20 ENST00000535523.5
ENST00000673764.1
dynein axonemal assembly factor 6
chrX_+_107206605 0.20 ENST00000372453.8
dynein axonemal assembly factor 6
chr2_+_148978361 0.20 ENST00000678720.1
ENST00000678856.1
ENST00000677080.1
kinesin family member 5C
chr3_-_119660580 0.19 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
popeye domain containing 2
chrX_-_139832235 0.19 ENST00000327569.7
ENST00000361648.6
ATPase phospholipid transporting 11C
chrX_-_131289412 0.19 ENST00000652189.1
ENST00000651556.1
immunoglobulin superfamily member 1
chr1_+_159439722 0.18 ENST00000641630.1
ENST00000423932.6
olfactory receptor family 10 subfamily J member 1
chr10_-_117005173 0.18 ENST00000355371.9
shootin 1
chr1_-_86914319 0.18 ENST00000611507.4
ENST00000616787.4
selenoprotein F
chr11_-_16356538 0.17 ENST00000683767.1
SRY-box transcription factor 6
chr10_-_117005349 0.17 ENST00000615301.4
shootin 1
chr14_+_22314435 0.16 ENST00000390467.3
T cell receptor alpha variable 40
chr7_-_72828171 0.16 ENST00000612372.4
ENST00000610600.1
ENST00000620995.5
tRNA-yW synthesizing protein 1 homolog B
chr1_+_180928133 0.16 ENST00000367587.1
KIAA1614
chr19_-_35528221 0.16 ENST00000588674.5
ENST00000452271.7
ENST00000518157.1
suprabasin
chr1_+_207752046 0.15 ENST00000367042.6
ENST00000322875.8
ENST00000322918.9
ENST00000354848.5
ENST00000357714.5
ENST00000358170.6
ENST00000367041.5
ENST00000367047.5
ENST00000360212.6
ENST00000480003.5
CD46 molecule
chr1_+_160739265 0.15 ENST00000368042.7
SLAM family member 7
chr13_+_113158642 0.15 ENST00000375547.7
ENST00000342783.5
protein Z, vitamin K dependent plasma glycoprotein
chr1_-_86914102 0.15 ENST00000331835.10
ENST00000401030.4
ENST00000370554.5
selenoprotein F
chr4_+_76074701 0.15 ENST00000355810.9
ENST00000349321.7
ADP-ribosyltransferase 3 (inactive)
chr8_+_127735597 0.15 ENST00000651626.1
MYC proto-oncogene, bHLH transcription factor
chr12_-_69699455 0.14 ENST00000266661.8
bestrophin 3
chr6_-_10412367 0.14 ENST00000379608.9
transcription factor AP-2 alpha
chr20_-_45515612 0.14 ENST00000217428.7
serine peptidase inhibitor, Kunitz type 3
chrX_-_66040072 0.14 ENST00000374737.9
V-set and immunoglobulin domain containing 4
chr7_-_152676130 0.14 ENST00000359321.2
X-ray repair cross complementing 2
chr2_+_191245473 0.13 ENST00000304164.8
myosin IB
chr2_+_29097705 0.13 ENST00000401605.5
ENST00000401617.6
CAP-Gly domain containing linker protein family member 4
chr3_-_197299067 0.13 ENST00000663148.1
discs large MAGUK scaffold protein 1
chrX_-_66040107 0.13 ENST00000455586.6
V-set and immunoglobulin domain containing 4
chr11_-_117876719 0.13 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr6_-_35512863 0.13 ENST00000428978.1
ENST00000614066.4
ENST00000322263.8
TUB like protein 1
chr3_+_108296489 0.13 ENST00000619531.4
HERV-H LTR-associating 2
chr8_-_123025750 0.13 ENST00000523036.1
derlin 1
chr11_-_117876892 0.12 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr18_+_58341038 0.12 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr10_-_88851809 0.12 ENST00000371930.5
ankyrin repeat domain 22
chrX_-_131289266 0.12 ENST00000370910.5
ENST00000370901.4
ENST00000361420.8
ENST00000370903.8
immunoglobulin superfamily member 1
chr8_-_3409528 0.12 ENST00000335551.11
CUB and Sushi multiple domains 1
chr6_-_42194947 0.12 ENST00000230361.4
guanylate cyclase activator 1B
chr5_-_801145 0.12 ENST00000424784.3
zinc finger DHHC-type containing 11
chr6_-_35512882 0.12 ENST00000229771.11
TUB like protein 1
chr1_-_95072936 0.12 ENST00000370205.6
ALG14 UDP-N-acetylglucosaminyltransferase subunit
chr12_-_69699331 0.12 ENST00000548658.1
ENST00000476098.5
bestrophin 3
chr10_+_12068945 0.11 ENST00000263035.9
dehydrogenase E1 and transketolase domain containing 1
chr3_-_197183806 0.11 ENST00000671246.1
ENST00000660553.1
discs large MAGUK scaffold protein 1
chr12_+_68686951 0.11 ENST00000378905.6
ENST00000229179.9
nucleoporin 107
chr19_-_55160668 0.11 ENST00000588076.1
dynein axonemal assembly factor 3
chr1_+_152719522 0.11 ENST00000368775.3
chromosome 1 open reading frame 68
chr21_+_38256698 0.11 ENST00000613499.4
ENST00000612702.4
ENST00000398925.5
ENST00000398928.5
ENST00000328656.8
ENST00000443341.5
potassium inwardly rectifying channel subfamily J member 15
chr1_-_10964201 0.11 ENST00000418570.6
chromosome 1 open reading frame 127
chr1_-_155991198 0.11 ENST00000673475.1
Rho/Rac guanine nucleotide exchange factor 2
chr17_+_59220446 0.11 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
glycerophosphodiester phosphodiesterase domain containing 1
chr7_-_102356444 0.10 ENST00000563237.3
speedy/RINGO cell cycle regulator family member E6
chr12_-_9999176 0.10 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr4_-_64409444 0.10 ENST00000381210.8
ENST00000507440.5
trans-2,3-enoyl-CoA reductase like
chr11_-_18791563 0.10 ENST00000396168.1
protein tyrosine phosphatase non-receptor type 5
chr19_+_15640880 0.10 ENST00000586182.6
ENST00000221307.13
ENST00000591058.5
cytochrome P450 family 4 subfamily F member 3
chr12_+_110847000 0.10 ENST00000552694.1
coiled-coil domain containing 63
chr14_+_55661272 0.10 ENST00000555573.5
kinectin 1
chr16_+_84768246 0.10 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr17_-_60422404 0.10 ENST00000588898.1
ubiquitin specific peptidase 32
chr1_+_147902789 0.10 ENST00000369235.2
gap junction protein alpha 8
chr14_+_67720842 0.10 ENST00000267502.3
retinol dehydrogenase 12
chr12_+_112978562 0.10 ENST00000680122.1
2'-5'-oligoadenylate synthetase 2
chr17_+_29941605 0.09 ENST00000394835.7
EF-hand calcium binding domain 5
chr12_+_110846960 0.09 ENST00000545036.5
ENST00000308208.10
coiled-coil domain containing 63
chr7_+_80638633 0.09 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr11_+_128693887 0.09 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_113049616 0.09 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr12_+_47079586 0.09 ENST00000432328.2
ENST00000546455.6
PC-esterase domain containing 1B
chr15_-_51751525 0.09 ENST00000454181.6
LysM domain containing 2
chr1_-_165768848 0.09 ENST00000367881.11
ENST00000464650.5
ENST00000612311.4
ENST00000628579.1
transmembrane and coiled-coil domains 1
chr3_-_36739791 0.09 ENST00000416516.2
doublecortin like kinase 3
chr11_-_18791768 0.09 ENST00000358540.7
protein tyrosine phosphatase non-receptor type 5
chr10_+_100462969 0.09 ENST00000343737.6
Wnt family member 8B
chr3_-_51903341 0.09 ENST00000310914.10
IQ motif containing F1
chr15_+_22838635 0.09 ENST00000398014.7
ENST00000359727.8
ENST00000674173.1
ENST00000337451.8
ENST00000674289.1
ENST00000674477.1
ENST00000398013.7
ENST00000674330.1
ENST00000560039.1
ENST00000539711.2
NIPA magnesium transporter 2
chr4_+_186227501 0.09 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr16_-_47459130 0.09 ENST00000565940.6
integrin alpha FG-GAP repeat containing 1
chr22_+_25742141 0.09 ENST00000536101.5
ENST00000335473.12
ENST00000407587.6
myosin XVIIIB
chr1_+_86914616 0.09 ENST00000370550.10
ENST00000370551.8
heparan sulfate 2-O-sulfotransferase 1
chr21_+_7748899 0.08 ENST00000623661.1
small integral membrane protein 11B
chr16_+_56936654 0.08 ENST00000563911.5
homocysteine inducible ER protein with ubiquitin like domain 1
chr13_+_95433593 0.08 ENST00000376873.7
claudin 10
chr6_-_134052594 0.08 ENST00000275230.6
solute carrier family 2 member 12
chr16_-_71230676 0.08 ENST00000321489.9
ENST00000539973.5
ENST00000288168.14
ENST00000545267.1
ENST00000541601.5
ENST00000393567.7
ENST00000538248.5
HYDIN axonemal central pair apparatus protein
chrX_+_100666854 0.08 ENST00000640282.1
sushi repeat containing protein X-linked 2
chr8_-_94475044 0.08 ENST00000297592.5
ENST00000336148.10
RAD54 homolog B
chr7_-_76541459 0.08 ENST00000632547.1
speedy/RINGO cell cycle regulator family member E16
chr13_+_112968496 0.08 ENST00000397030.5
MCF.2 cell line derived transforming sequence like
chr3_-_197299281 0.08 ENST00000419354.5
ENST00000667104.1
ENST00000658701.1
discs large MAGUK scaffold protein 1
chr22_+_21420636 0.08 ENST00000407598.2
HIC ZBTB transcriptional repressor 2
chr8_+_22059169 0.08 ENST00000358242.5
dematin actin binding protein
chr8_-_21913671 0.08 ENST00000523932.1
ENST00000276420.9
docking protein 2
chr3_-_128467248 0.08 ENST00000319153.3
DnaJ heat shock protein family (Hsp40) member B8
chr3_-_197183849 0.07 ENST00000443183.5
discs large MAGUK scaffold protein 1
chr20_+_4721901 0.07 ENST00000305817.3
prion like protein doppel
chr18_-_48137295 0.07 ENST00000535628.6
zinc finger and BTB domain containing 7C
chr12_-_14950606 0.07 ENST00000536592.5
Rho GDP dissociation inhibitor beta
chr19_+_35448251 0.07 ENST00000599180.3
free fatty acid receptor 2
chr4_-_67883987 0.07 ENST00000283916.11
transmembrane serine protease 11D
chr3_+_171843337 0.07 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr20_+_59163810 0.07 ENST00000371030.4
zinc finger protein 831
chr10_+_35605337 0.07 ENST00000321660.2
gap junction protein delta 4
chr18_+_13611429 0.07 ENST00000587757.5
low density lipoprotein receptor class A domain containing 4
chr10_+_5692792 0.07 ENST00000645567.1
transcription activation suppressor family member 2
chr17_-_69150062 0.07 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr5_+_80408031 0.07 ENST00000505560.5
ENST00000509562.2
zinc finger FYVE-type containing 16
chr8_-_67746348 0.07 ENST00000297770.10
carboxypeptidase A6
chr2_-_28870266 0.07 ENST00000306108.10
tRNA methyltransferase 61B
chr12_-_44875647 0.07 ENST00000395487.6
neural EGFL like 2
chr9_+_131190119 0.07 ENST00000483497.6
nucleoporin 214
chr4_+_113049479 0.06 ENST00000671727.1
ENST00000671762.1
ENST00000672366.1
ENST00000672502.1
ENST00000672045.1
ENST00000672251.1
ENST00000672854.1
ankyrin 2
chr5_+_80407994 0.06 ENST00000338008.9
ENST00000510158.5
zinc finger FYVE-type containing 16
chr8_+_22059198 0.06 ENST00000523266.5
ENST00000519907.5
dematin actin binding protein
chr19_-_5867741 0.06 ENST00000252675.6
fucosyltransferase 5
chr2_-_677367 0.06 ENST00000281017.8
transmembrane protein 18
chr13_+_25301587 0.06 ENST00000381736.8
ENST00000463407.5
ENST00000381718.7
ENST00000381747.7
nucleoporin 58
chr7_+_112480853 0.06 ENST00000439068.6
ENST00000312849.4
leucine rich single-pass membrane protein 1
chr8_-_58500158 0.06 ENST00000301645.4
cytochrome P450 family 7 subfamily A member 1
chr21_+_38256984 0.06 ENST00000398938.7
potassium inwardly rectifying channel subfamily J member 15
chr16_-_3717505 0.06 ENST00000538171.5
ENST00000246957.10
TNF receptor associated protein 1
chr8_+_120445402 0.06 ENST00000305949.6
MDM2 binding protein
chrX_+_48383516 0.06 ENST00000620320.4
ENST00000595689.3
SSX family member 4
chr5_+_40909490 0.06 ENST00000313164.10
complement C7
chr4_-_145180496 0.06 ENST00000447906.8
OTU deubiquitinase 4
chr3_-_112133218 0.06 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
germinal center associated signaling and motility
chr2_-_54987578 0.06 ENST00000486085.5
reticulon 4
chr5_+_96876480 0.05 ENST00000437043.8
ENST00000379904.8
endoplasmic reticulum aminopeptidase 2
chr1_+_62194831 0.05 ENST00000498273.2
LINE1 type transposase domain containing 1
chr14_+_63761836 0.05 ENST00000674003.1
spectrin repeat containing nuclear envelope protein 2
chr2_-_219245389 0.05 ENST00000428427.1
ENST00000432839.1
ENST00000295759.12
ENST00000424620.1
galactosidase beta 1 like
chr21_-_14658812 0.05 ENST00000647101.1
SAM domain, SH3 domain and nuclear localization signals 1
chr19_-_53824288 0.05 ENST00000324134.11
ENST00000391773.6
ENST00000391775.7
ENST00000345770.9
ENST00000391772.1
NLR family pyrin domain containing 12
chr2_-_162074394 0.05 ENST00000676810.1
dipeptidyl peptidase 4
chr15_-_84654270 0.05 ENST00000434634.7
WD repeat domain 73
chr1_+_207645114 0.05 ENST00000508064.7
complement C3b/C4b receptor 1 like
chr12_-_44876294 0.05 ENST00000429094.7
ENST00000551601.5
ENST00000549027.5
ENST00000452445.6
neural EGFL like 2
chr9_+_84668485 0.05 ENST00000359847.4
ENST00000395882.6
ENST00000376208.6
ENST00000376213.6
neurotrophic receptor tyrosine kinase 2
chr10_+_116590956 0.05 ENST00000358834.9
ENST00000528052.5
pancreatic lipase related protein 1
chr10_-_100229550 0.05 ENST00000370397.8
component of inhibitor of nuclear factor kappa B kinase complex
chr10_+_116591010 0.05 ENST00000530319.5
ENST00000527980.5
ENST00000471549.5
ENST00000534537.5
pancreatic lipase related protein 1
chr7_+_76480510 0.05 ENST00000446820.6
deltex E3 ubiquitin ligase 2
chr5_-_142698004 0.05 ENST00000407758.5
ENST00000441680.6
ENST00000419524.6
ENST00000621536.4
fibroblast growth factor 1
chrX_-_54998530 0.05 ENST00000545676.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_+_63204859 0.05 ENST00000555125.1
ras homolog family member J
chr11_-_117876612 0.04 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr17_+_44142015 0.04 ENST00000245382.6
homologous recombination factor with OB-fold
chr15_+_51681483 0.04 ENST00000542355.6
ENST00000220478.8
ENST00000558709.1
secretogranin III
chr1_-_54623518 0.04 ENST00000302250.7
ENST00000371304.2
family with sequence similarity 151 member A
chr4_+_70197924 0.04 ENST00000514097.5
odontogenic, ameloblast associated
chr1_-_184037695 0.04 ENST00000361927.9
ENST00000649786.1
collagen beta(1-O)galactosyltransferase 2
chr15_-_25346012 0.04 ENST00000636667.1
ubiquitin protein ligase E3A
chr2_+_201790461 0.04 ENST00000410091.7
cyclin dependent kinase 15
chr17_-_2511875 0.04 ENST00000263092.11
ENST00000576976.2
methyltransferase like 16
chr7_+_69824565 0.04 ENST00000643587.1
activator of transcription and developmental regulator AUTS2
chr17_-_35560812 0.04 ENST00000674182.1
schlafen family member 14
chr10_+_95711750 0.04 ENST00000453258.6
ectonucleoside triphosphate diphosphohydrolase 1
chr1_+_167329044 0.04 ENST00000367862.9
POU class 2 homeobox 1
chr10_+_112376193 0.04 ENST00000433418.6
ENST00000356116.6
ENST00000354273.5
acyl-CoA synthetase long chain family member 5
chr9_-_114682061 0.04 ENST00000612244.5
testis expressed 48
chr18_+_21242254 0.04 ENST00000269218.10
GREB1 like retinoic acid receptor coactivator
chr10_-_133626792 0.04 ENST00000443774.5
ENST00000425520.2
FSHD region gene 2 family member B
chr11_+_844406 0.04 ENST00000397404.5
tetraspanin 4
chr1_-_165768835 0.04 ENST00000481278.5
transmembrane and coiled-coil domains 1
chrX_-_124963768 0.04 ENST00000371130.7
ENST00000422452.2
teneurin transmembrane protein 1
chr12_+_6840800 0.04 ENST00000541978.5
ENST00000229264.8
ENST00000435982.6
G protein subunit beta 3
chr1_+_163321942 0.04 ENST00000271452.8
NUF2 component of NDC80 kinetochore complex

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.6 GO:0061163 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
0.2 1.9 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.4 GO:0042223 response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.5 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.5 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.4 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.0 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.2 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.5 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.4 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 2.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.0 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.0 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 2.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors