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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PBX3

Z-value: 0.97

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Transcription factors associated with PBX3

Gene Symbol Gene ID Gene Info
ENSG00000167081.18 PBX homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX3hg38_v1_chr9_+_125747345_125747380-0.167.1e-01Click!

Activity profile of PBX3 motif

Sorted Z-values of PBX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_45009401 1.51 ENST00000303077.7
SIX homeobox 2
chr12_-_91179472 1.18 ENST00000550099.5
ENST00000546391.5
decorin
chr7_+_149873956 1.14 ENST00000425642.3
ENST00000479613.5
ENST00000606024.5
ENST00000464662.5
ATPase H+ transporting V0 subunit e2
chr12_-_91179355 1.13 ENST00000550563.5
ENST00000546370.5
decorin
chrX_-_155022716 1.07 ENST00000360256.9
coagulation factor VIII
chr17_+_60677822 0.72 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr6_-_84764581 0.63 ENST00000369663.10
T-box transcription factor 18
chr17_+_63622406 0.63 ENST00000579585.5
ENST00000361733.8
ENST00000584573.5
ENST00000361357.7
mitogen-activated protein kinase kinase kinase 3
chr21_-_37916440 0.61 ENST00000609713.2
potassium inwardly rectifying channel subfamily J member 6
chr4_+_123396785 0.61 ENST00000505319.5
ENST00000651917.1
ENST00000610581.4
ENST00000339241.1
sprouty RTK signaling antagonist 1
chr19_+_19865905 0.59 ENST00000355650.4
zinc finger protein 253
chr19_-_12484773 0.59 ENST00000397732.8
zinc finger protein 709
chr19_+_11987634 0.55 ENST00000652448.1
ENST00000495324.5
novel protein
ZNF433 and ZNF878 antisense RNA 1
chr4_-_137532452 0.53 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chrX_+_103776831 0.52 ENST00000621218.5
ENST00000619236.1
proteolipid protein 1
chrX_+_103776493 0.51 ENST00000433491.5
ENST00000612423.4
ENST00000443502.5
proteolipid protein 1
chr19_+_19865874 0.46 ENST00000589717.2
ENST00000592725.1
zinc finger protein 253
chr4_-_174522791 0.46 ENST00000541923.5
ENST00000542498.5
15-hydroxyprostaglandin dehydrogenase
chr2_+_200306648 0.45 ENST00000409140.8
spermatogenesis associated serine rich 2 like
chr19_+_22832284 0.45 ENST00000600766.3
zinc finger protein 723
chr19_-_12401247 0.45 ENST00000595766.1
ENST00000430385.3
ENST00000435033.1
zinc finger protein 799
novel transcript
chr4_-_174522446 0.44 ENST00000296521.11
ENST00000296522.11
ENST00000422112.6
ENST00000504433.1
15-hydroxyprostaglandin dehydrogenase
chr1_+_164559173 0.44 ENST00000420696.7
PBX homeobox 1
chr19_-_12365628 0.43 ENST00000438182.5
zinc finger protein 442
chr4_+_159103010 0.42 ENST00000644474.1
Rap guanine nucleotide exchange factor 2
chr10_+_74826406 0.42 ENST00000648892.1
ENST00000647890.1
ENST00000372724.6
lysine acetyltransferase 6B
chr16_+_85027735 0.42 ENST00000258180.7
ENST00000538274.5
KIAA0513
chr16_+_85027761 0.42 ENST00000683363.1
KIAA0513
chr8_-_56211257 0.41 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1 zinc finger
chr10_+_74826550 0.40 ENST00000649657.1
ENST00000372714.6
ENST00000649442.1
ENST00000648539.1
ENST00000647666.1
ENST00000648048.1
ENST00000287239.10
ENST00000649375.1
lysine acetyltransferase 6B
chr9_-_35689913 0.39 ENST00000329305.6
ENST00000645482.3
ENST00000647435.1
ENST00000378292.9
tropomyosin 2
chr9_+_36036899 0.39 ENST00000377966.4
reversion inducing cysteine rich protein with kazal motifs
chr19_+_16324817 0.38 ENST00000248071.6
ENST00000592003.1
Kruppel like factor 2
chr11_-_106022209 0.38 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr22_+_35299800 0.37 ENST00000456128.5
ENST00000411850.5
ENST00000425375.5
ENST00000449058.7
target of myb1 membrane trafficking protein
chr7_-_50782853 0.36 ENST00000401949.6
growth factor receptor bound protein 10
chr4_-_174522315 0.36 ENST00000514584.5
15-hydroxyprostaglandin dehydrogenase
chr6_-_41705813 0.35 ENST00000419574.6
ENST00000445214.2
transcription factor EB
chr1_+_222928415 0.35 ENST00000284476.7
dispatched RND transporter family member 1
chrX_-_71254527 0.34 ENST00000373978.1
ENST00000373981.5
zinc finger MYM-type containing 3
chr19_-_23395418 0.33 ENST00000595533.1
ENST00000397082.2
ENST00000599743.5
ENST00000300619.12
zinc finger protein 91
chr7_+_134646845 0.33 ENST00000344924.8
bisphosphoglycerate mutase
chr9_-_120477354 0.33 ENST00000416449.5
CDK5 regulatory subunit associated protein 2
chr1_-_145957969 0.32 ENST00000604000.4
limb and CNS expressed 1 like
chr19_+_10420474 0.32 ENST00000380702.7
phosphodiesterase 4A
chr19_-_12365655 0.31 ENST00000242804.9
zinc finger protein 442
chr22_-_19881369 0.31 ENST00000462330.5
thioredoxin reductase 2
chr9_-_116687205 0.31 ENST00000288520.9
ENST00000358637.4
ENST00000341734.8
astrotactin 2
chr2_+_20447065 0.30 ENST00000272233.6
ras homolog family member B
chr14_-_106811131 0.30 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr19_-_12551426 0.30 ENST00000416136.1
ENST00000339282.12
ENST00000596193.1
ENST00000428311.1
zinc finger protein 564
novel zinc finger protein
chr8_+_56211686 0.30 ENST00000521831.5
ENST00000303759.3
ENST00000517636.5
ENST00000517933.5
ENST00000355315.8
ENST00000518801.5
ENST00000523975.5
ENST00000396723.9
ENST00000523061.5
ENST00000521524.5
coiled-coil-helix-coiled-coil-helix domain containing 7
chr3_-_187736493 0.30 ENST00000232014.8
BCL6 transcription repressor
chr19_-_21329400 0.30 ENST00000356929.3
zinc finger protein 708
chr7_+_134646798 0.29 ENST00000418040.5
ENST00000393132.2
bisphosphoglycerate mutase
chr19_-_12140315 0.29 ENST00000418866.1
ENST00000600335.5
ENST00000334213.10
zinc finger protein 20
chr10_-_43648704 0.29 ENST00000395797.1
zinc finger protein 32
chr22_-_19881163 0.29 ENST00000485358.5
thioredoxin reductase 2
chr19_-_11738882 0.29 ENST00000586121.1
ENST00000431998.1
ENST00000341191.11
ENST00000440527.1
zinc finger protein 823
chr19_+_11766989 0.29 ENST00000357901.5
zinc finger protein 441
chr11_-_2149603 0.29 ENST00000643349.1
novel protein
chr10_-_43648845 0.28 ENST00000374433.7
zinc finger protein 32
chr7_-_13989658 0.28 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr1_+_1001002 0.28 ENST00000624697.4
ENST00000624652.1
ISG15 ubiquitin like modifier
chr5_-_81751085 0.28 ENST00000515395.5
single stranded DNA binding protein 2
chr18_+_3448456 0.28 ENST00000549780.5
TGFB induced factor homeobox 1
chr20_+_41136944 0.27 ENST00000244007.7
phospholipase C gamma 1
chr6_+_31652414 0.27 ENST00000375918.6
ENST00000375920.8
apolipoprotein M
chr5_-_81751022 0.27 ENST00000509013.2
ENST00000505980.5
ENST00000509053.5
single stranded DNA binding protein 2
chr7_+_90709816 0.27 ENST00000436577.3
cyclin dependent kinase 14
chr19_+_48954850 0.26 ENST00000345358.12
ENST00000539787.2
ENST00000415969.6
ENST00000354470.7
ENST00000506183.5
ENST00000391871.4
ENST00000293288.12
BCL2 associated X, apoptosis regulator
chr1_-_109740304 0.26 ENST00000540225.2
glutathione S-transferase mu 3
chr7_-_138701352 0.26 ENST00000421622.5
ENST00000674285.1
SVOP like
chr7_+_90709530 0.25 ENST00000406263.5
cyclin dependent kinase 14
chr19_-_12294819 0.25 ENST00000355684.6
ENST00000356109.10
zinc finger protein 44
chrX_+_9560465 0.25 ENST00000647060.1
transducin beta like 1 X-linked
chr11_-_842508 0.24 ENST00000322028.5
RNA polymerase II, I and III subunit L
chrX_-_40177213 0.24 ENST00000672922.2
ENST00000378455.8
ENST00000342274.8
BCL6 corepressor
chr5_-_81751103 0.24 ENST00000514493.5
ENST00000320672.8
ENST00000615665.4
single stranded DNA binding protein 2
chr8_-_77000194 0.24 ENST00000522527.5
peroxisomal biogenesis factor 2
chr7_-_23470469 0.24 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chrX_+_103376488 0.24 ENST00000361298.9
brain expressed X-linked 3
chr11_+_62611722 0.23 ENST00000525801.1
ENST00000534093.5
retinal outer segment membrane protein 1
chr19_-_12333626 0.23 ENST00000293725.10
zinc finger protein 563
chr19_-_55461597 0.23 ENST00000589080.1
ENST00000425675.7
ENST00000085068.7
isochorismatase domain containing 2
chr7_-_13989891 0.23 ENST00000405218.6
ETS variant transcription factor 1
chr5_-_172283743 0.23 ENST00000393792.3
ubiquitin domain containing 2
chrX_+_10156960 0.23 ENST00000380833.9
chloride voltage-gated channel 4
chr19_+_12163049 0.22 ENST00000425827.5
ENST00000439995.5
ENST00000652580.1
ENST00000343979.6
ENST00000418338.1
zinc finger protein 136
chr4_-_88284616 0.22 ENST00000508256.5
protein phosphatase, Mg2+/Mn2+ dependent 1K
chrX_+_103376389 0.22 ENST00000372645.3
ENST00000372635.1
brain expressed X-linked 3
chr7_+_90709231 0.22 ENST00000446790.5
ENST00000265741.7
cyclin dependent kinase 14
chrX_+_103628959 0.22 ENST00000372625.8
ENST00000372624.3
transcription elongation factor A like 1
chr2_+_74458400 0.22 ENST00000393972.7
ENST00000233615.7
ENST00000409737.5
ENST00000428943.1
WW domain binding protein 1
chr14_+_60509138 0.22 ENST00000327720.6
SIX homeobox 6
chr4_-_88284590 0.22 ENST00000510548.6
protein phosphatase, Mg2+/Mn2+ dependent 1K
chrX_+_71254781 0.22 ENST00000677446.1
non-POU domain containing octamer binding
chr13_+_23579346 0.22 ENST00000382258.8
ENST00000382263.3
TNF receptor superfamily member 19
chr13_-_19863630 0.22 ENST00000337963.9
zinc finger MYM-type containing 5
chr3_-_165196369 0.22 ENST00000475390.2
SLIT and NTRK like family member 3
chr5_-_141320755 0.22 ENST00000624761.1
ENST00000313368.8
TATA-box binding protein associated factor 7
chrX_-_108438407 0.21 ENST00000334504.12
ENST00000621266.4
ENST00000538570.5
ENST00000394872.6
ENST00000545689.2
collagen type IV alpha 6 chain
chr15_+_92900338 0.21 ENST00000625990.3
chromodomain helicase DNA binding protein 2
chr3_+_123201920 0.21 ENST00000492595.6
ENST00000473494.6
ENST00000481965.6
SEC22 homolog A, vesicle trafficking protein
chr6_-_35688907 0.21 ENST00000539068.5
ENST00000357266.9
FKBP prolyl isomerase 5
chr15_-_43493076 0.21 ENST00000413546.1
tumor protein p53 binding protein 1
chr1_+_65264694 0.21 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chrX_+_53082358 0.20 ENST00000375442.8
ENST00000579390.1
TSPY like 2
chrX_-_154409246 0.20 ENST00000369807.6
deoxyribonuclease 1 like 1
chr16_-_53503192 0.20 ENST00000568596.5
ENST00000394657.12
ENST00000570004.5
ENST00000564497.1
ENST00000300245.8
AKT interacting protein
chr19_-_12441012 0.20 ENST00000301547.10
zinc finger protein 443
chr5_-_108382080 0.20 ENST00000542267.7
F-box and leucine rich repeat protein 17
chr2_+_61162185 0.20 ENST00000432605.3
ENST00000488469.4
chromosome 2 open reading frame 74
chr20_-_46089905 0.20 ENST00000372291.3
ENST00000290231.11
nuclear receptor coactivator 5
chr17_+_41819201 0.20 ENST00000455106.1
FKBP prolyl isomerase 10
chr3_-_3179674 0.19 ENST00000424814.5
ENST00000450014.1
ENST00000231948.9
ENST00000432408.6
ENST00000639284.1
cereblon
chr1_+_6785518 0.19 ENST00000467404.6
calmodulin binding transcription activator 1
chr4_+_73481737 0.19 ENST00000226355.5
afamin
chr1_+_7771263 0.19 ENST00000054666.11
vesicle associated membrane protein 3
chrX_-_154409278 0.19 ENST00000369808.7
deoxyribonuclease 1 like 1
chr19_+_40576849 0.19 ENST00000600733.5
ENST00000291842.10
ENST00000600718.5
SH3KBP1 binding protein 1
chr12_-_91179517 0.19 ENST00000551354.1
decorin
chr7_-_38363476 0.18 ENST00000426402.2
T cell receptor gamma variable 2
chr21_+_42974510 0.18 ENST00000432907.6
ENST00000291547.10
PBX/knotted 1 homeobox 1
chr8_+_26383043 0.18 ENST00000380629.7
BCL2 interacting protein 3 like
chr11_+_67483019 0.18 ENST00000279146.8
ENST00000528641.7
ENST00000682324.1
ENST00000684006.1
ENST00000683237.1
ENST00000684657.1
aryl hydrocarbon receptor interacting protein
chr9_+_34652167 0.18 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chrX_-_134915203 0.18 ENST00000370779.8
motile sperm domain containing 1
chr8_-_92966129 0.18 ENST00000522925.5
ENST00000522903.5
ENST00000537541.1
ENST00000521988.6
ENST00000518748.5
ENST00000519069.5
triple QxxK/R motif containing
chr20_-_35411963 0.18 ENST00000349714.9
ENST00000438533.5
ENST00000359226.6
ENST00000374384.6
ENST00000374385.10
ENST00000424405.5
ENST00000397554.5
ENST00000374380.6
ubiquinol-cytochrome c reductase complex assembly factor 1
chr15_+_24823625 0.18 ENST00000400100.5
ENST00000645002.1
ENST00000642807.1
small nuclear ribonucleoprotein polypeptide N
chr7_+_100101657 0.17 ENST00000421755.5
adaptor related protein complex 4 subunit mu 1
chr3_-_88058928 0.17 ENST00000482016.6
CGG triplet repeat binding protein 1
chr19_-_14117729 0.17 ENST00000590853.5
ENST00000308677.9
protein kinase cAMP-activated catalytic subunit alpha
chr10_+_101031223 0.17 ENST00000393459.5
ENST00000224807.9
sideroflexin 3
chr10_+_132537814 0.17 ENST00000368593.7
inositol polyphosphate-5-phosphatase A
chr3_+_88059231 0.17 ENST00000636215.2
zinc finger protein 654
chr2_+_172085499 0.17 ENST00000361725.5
ENST00000341900.6
distal-less homeobox 1
chr7_+_107168961 0.17 ENST00000468410.5
ENST00000478930.5
ENST00000464009.1
ENST00000222574.9
HMG-box transcription factor 1
chr16_+_28878382 0.17 ENST00000357084.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr3_+_15601720 0.17 ENST00000673620.1
biotinidase
chr12_+_51239278 0.17 ENST00000551313.1
DAZ associated protein 2
chr10_+_87357720 0.17 ENST00000412718.3
ENST00000381697.7
NUT family member 2D
chr2_-_215436061 0.16 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
fibronectin 1
chr7_+_65373873 0.16 ENST00000450302.2
zinc finger protein 92
chr19_+_21142024 0.16 ENST00000600692.5
ENST00000599296.5
ENST00000594425.5
ENST00000311048.11
zinc finger protein 431
chr22_-_36776067 0.16 ENST00000417951.6
ENST00000433985.7
ENST00000430701.5
intraflagellar transport 27
chr3_-_88059042 0.16 ENST00000309534.10
CGG triplet repeat binding protein 1
chr12_-_56221701 0.16 ENST00000615206.4
ENST00000549038.5
ENST00000552244.5
ring finger protein 41
chr12_+_75480745 0.16 ENST00000266659.8
GLI pathogenesis related 1
chr5_-_37249281 0.16 ENST00000651892.2
ciliogenesis and planar polarity effector 1
chr22_+_42079688 0.16 ENST00000331479.4
single-pass membrane protein with aspartate rich tail 1
chr19_-_49560650 0.16 ENST00000598296.5
nitric oxide synthase interacting protein
chr19_-_38831659 0.16 ENST00000601094.5
ENST00000595567.1
ENST00000602115.1
ENST00000601778.5
ENST00000597205.1
ENST00000595470.1
ENST00000221418.9
enoyl-CoA hydratase 1
chr19_+_10013468 0.16 ENST00000591589.3
retinol dehydrogenase 8
chr17_-_8630749 0.16 ENST00000379980.8
ENST00000269243.8
myosin heavy chain 10
chr12_+_75481204 0.16 ENST00000550491.1
GLI pathogenesis related 1
chr10_+_79703227 0.16 ENST00000429828.5
ENST00000372321.5
NUT family member 2B
chr10_+_97498881 0.16 ENST00000370664.4
ubiquitin domain containing 1
chr1_+_6785437 0.15 ENST00000303635.12
ENST00000473578.5
ENST00000557126.5
calmodulin binding transcription activator 1
chr1_+_85062304 0.15 ENST00000326813.12
ENST00000528899.5
ENST00000294664.11
dynein axonemal intermediate chain 3
chr19_-_4867649 0.15 ENST00000592528.5
ENST00000589494.1
ENST00000221957.9
perilipin 3
chr7_+_100101556 0.15 ENST00000438383.5
ENST00000429084.5
ENST00000439416.5
adaptor related protein complex 4 subunit mu 1
chr14_+_75661186 0.15 ENST00000556977.5
ENST00000298832.14
ENST00000557636.5
ENST00000286650.9
tubulin tyrosine ligase like 5
chr16_+_28878480 0.15 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr7_+_65373799 0.15 ENST00000357512.3
zinc finger protein 92
chr4_+_337791 0.15 ENST00000240499.8
ENST00000512994.5
ENST00000505939.5
zinc finger protein 141
chr7_+_65373839 0.15 ENST00000431504.1
ENST00000328747.12
zinc finger protein 92
chr6_+_63211446 0.15 ENST00000370659.1
FKBP prolyl isomerase family member 1C
chr16_-_2210833 0.15 ENST00000562360.5
ENST00000328540.8
ENST00000566018.1
BRICHOS domain containing 5
chr4_-_2418608 0.15 ENST00000503000.1
zinc finger FYVE-type containing 28
chr22_-_36776147 0.15 ENST00000340630.9
intraflagellar transport 27
chrX_-_65034707 0.15 ENST00000337990.2
zinc finger C4H2-type containing
chr17_-_8630713 0.15 ENST00000411957.1
ENST00000360416.8
myosin heavy chain 10
chr1_-_28643005 0.15 ENST00000263974.4
ENST00000373824.9
ENST00000495422.2
TATA-box binding protein associated factor 12
chr4_+_124491 0.15 ENST00000510175.6
ENST00000609714.1
zinc finger protein 718
chr19_-_3700390 0.15 ENST00000679885.1
ENST00000537021.1
ENST00000589578.5
ENST00000539785.5
ENST00000335312.8
phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
chr5_+_43603163 0.15 ENST00000660752.1
ENST00000654405.1
ENST00000344920.9
ENST00000657172.1
ENST00000512996.6
ENST00000671668.1
nicotinamide nucleotide transhydrogenase
chr19_-_12156710 0.15 ENST00000455799.1
ENST00000439556.3
zinc finger protein 625
chr19_-_22010930 0.15 ENST00000601773.5
ENST00000397126.9
ENST00000609966.5
ENST00000601993.1
ENST00000599916.5
zinc finger protein 208
chrX_-_47659128 0.15 ENST00000333119.7
ENST00000335890.3
ubiquitously expressed prefoldin like chaperone
chr7_+_55365317 0.15 ENST00000254770.3
LanC like 2
chr2_+_44168866 0.15 ENST00000282412.9
ENST00000409432.7
ENST00000378551.6
ENST00000345249.8
protein phosphatase, Mg2+/Mn2+ dependent 1B
chr19_-_19733091 0.15 ENST00000344099.4
zinc finger protein 14
chr17_+_78231310 0.15 ENST00000374946.7
ENST00000421688.5
ENST00000586400.5
transmembrane protein 235
chr12_-_123233097 0.14 ENST00000541437.5
ENST00000606320.6
M-phase phosphoprotein 9
chr12_-_56221909 0.14 ENST00000394013.6
ENST00000345093.9
ENST00000551711.5
ENST00000552656.5
ring finger protein 41
chr19_-_21767498 0.14 ENST00000608416.5
ENST00000598026.1
zinc finger protein 100
chr9_-_35115839 0.14 ENST00000378566.5
ENST00000322813.10
family with sequence similarity 214 member B
chr8_-_92966105 0.14 ENST00000524037.5
ENST00000520430.5
ENST00000521617.5
ENST00000523580.5
triple QxxK/R motif containing
chr2_-_197786238 0.14 ENST00000282278.12
boule homolog, RNA binding protein
chr12_+_8509460 0.14 ENST00000382064.6
C-type lectin domain family 4 member D
chrX_-_70289888 0.14 ENST00000239666.9
ENST00000374454.1
PDZ domain containing 11
chr13_-_19863508 0.14 ENST00000382907.8
ENST00000382905.8
zinc finger MYM-type containing 5
chr15_-_43493105 0.14 ENST00000382039.7
ENST00000450115.6
ENST00000382044.9
tumor protein p53 binding protein 1
chr7_-_101321723 0.14 ENST00000498704.6
ENST00000517481.5
ENST00000437644.2
ENST00000315322.10
ENST00000621899.4
intraflagellar transport 22
chr22_+_42553994 0.14 ENST00000407614.8
ENST00000335879.5
serine hydrolase like 2
chr8_-_92966081 0.14 ENST00000517858.5
ENST00000378861.9
triple QxxK/R motif containing
chr10_-_22003678 0.14 ENST00000376980.8
DnaJ heat shock protein family (Hsp40) member C1
chr4_-_174283614 0.14 ENST00000513696.1
ENST00000393674.7
ENST00000503293.5
F-box protein 8

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168) positive regulation of chondrocyte proliferation(GO:1902732)
0.2 0.6 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.2 0.6 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 2.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.4 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.1 0.3 GO:0007225 patched ligand maturation(GO:0007225) signal maturation(GO:0035638)
0.1 0.3 GO:0031443 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076)
0.1 1.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.3 GO:1902869 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.6 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.3 GO:0002339 B cell selection(GO:0002339) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.4 GO:2000670 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.3 GO:0021592 fourth ventricle development(GO:0021592)
0.1 0.3 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.3 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.2 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 1.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.3 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.4 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0009946 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 1.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 1.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.4 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.7 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.2 GO:0015846 polyamine transport(GO:0015846)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.5 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.0 0.1 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.4 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.0 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.0 0.2 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:2000327 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.0 GO:1904397 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.4 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.6 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.0 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.1 GO:2000769 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219) retina vasculature development in camera-type eye(GO:0061298)
0.0 0.6 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 1.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.2 0.7 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.6 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.5 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.1 0.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0047708 biotinidase activity(GO:0047708)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.1 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.6 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.0 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis