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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for POU3F2

Z-value: 0.79

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Transcription factors associated with POU3F2

Gene Symbol Gene ID Gene Info
ENSG00000184486.10 POU class 3 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU3F2hg38_v1_chr6_+_98834560_988345820.571.4e-01Click!

Activity profile of POU3F2 motif

Sorted Z-values of POU3F2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_63887698 1.18 ENST00000457692.5
ENST00000299502.9
ENST00000413956.5
serpin family B member 2
chr5_+_140848360 0.88 ENST00000532602.2
protocadherin alpha 9
chr11_-_118252279 0.51 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
myelin protein zero like 3
chr18_+_31447732 0.50 ENST00000257189.5
desmoglein 3
chr8_-_15238423 0.49 ENST00000382080.6
sarcoglycan zeta
chr1_-_242449478 0.49 ENST00000427495.5
phospholipase D family member 5
chr2_-_112784486 0.47 ENST00000263339.4
interleukin 1 alpha
chr5_+_140834230 0.44 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr1_+_101238090 0.42 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr4_-_152679984 0.41 ENST00000304385.8
ENST00000504064.1
transmembrane protein 154
chr6_+_54846735 0.40 ENST00000306858.8
family with sequence similarity 83 member B
chr4_-_15938740 0.39 ENST00000382333.2
fibroblast growth factor binding protein 1
chr8_-_85341705 0.39 ENST00000517618.5
carbonic anhydrase 1
chr2_-_112836702 0.36 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr18_+_63777773 0.36 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr18_+_63775395 0.36 ENST00000398019.7
serpin family B member 7
chr5_+_140786136 0.35 ENST00000378133.4
ENST00000504120.4
protocadherin alpha 1
chr18_+_23949847 0.35 ENST00000588004.1
laminin subunit alpha 3
chr6_+_106086316 0.34 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr19_+_35115912 0.34 ENST00000603181.5
FXYD domain containing ion transport regulator 3
chr8_-_6978634 0.33 ENST00000382679.2
defensin alpha 1
chrX_+_106693838 0.33 ENST00000324342.7
ring finger protein 128
chr13_-_20230970 0.32 ENST00000644667.1
ENST00000646108.1
gap junction protein beta 6
chr15_+_43593054 0.32 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr2_-_216013582 0.32 ENST00000620139.4
melanoregulin
chr11_-_5301946 0.32 ENST00000380224.2
olfactory receptor family 51 subfamily B member 4
chr19_-_6720641 0.31 ENST00000245907.11
complement C3
chr5_+_140841183 0.30 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr11_-_102798148 0.30 ENST00000315274.7
matrix metallopeptidase 1
chr20_+_59721210 0.30 ENST00000395636.6
ENST00000361300.4
phosphatase and actin regulator 3
chr4_-_71784046 0.30 ENST00000513476.5
ENST00000273951.13
GC vitamin D binding protein
chr12_-_11134644 0.30 ENST00000539585.1
taste 2 receptor member 30
chr1_+_31576485 0.30 ENST00000457433.6
ENST00000271064.12
tubulointerstitial nephritis antigen like 1
chr18_+_63775369 0.29 ENST00000540675.5
serpin family B member 7
chr6_+_47656436 0.29 ENST00000507065.5
ENST00000296862.5
adhesion G protein-coupled receptor F2
chr6_+_30888672 0.29 ENST00000446312.5
discoidin domain receptor tyrosine kinase 1
chr10_+_116427839 0.29 ENST00000369230.4
pancreatic lipase related protein 3
chr18_+_63752935 0.29 ENST00000425392.5
ENST00000336429.6
serpin family B member 7
chr12_-_11022620 0.28 ENST00000390673.2
taste 2 receptor member 19
chr15_-_78944985 0.28 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
cathepsin H
chr18_+_49562049 0.28 ENST00000261292.9
ENST00000427224.6
ENST00000580036.5
lipase G, endothelial type
chr9_+_21409116 0.28 ENST00000380205.2
interferon alpha 8
chr21_+_38272410 0.28 ENST00000398934.5
ENST00000398930.5
potassium inwardly rectifying channel subfamily J member 15
chr1_+_86547070 0.28 ENST00000370563.3
chloride channel accessory 4
chr12_-_11062294 0.28 ENST00000533467.1
taste 2 receptor member 46
chr12_-_84892120 0.27 ENST00000680379.1
solute carrier family 6 member 15
chr6_+_29306626 0.26 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr8_+_18391276 0.26 ENST00000286479.4
ENST00000520116.1
N-acetyltransferase 2
chr19_+_35115872 0.26 ENST00000435734.6
FXYD domain containing ion transport regulator 3
chr18_+_23873000 0.26 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr7_-_20217342 0.25 ENST00000400331.10
ENST00000332878.8
MET transcriptional regulator MACC1
chr12_+_8822610 0.25 ENST00000299698.12
alpha-2-macroglobulin like 1
chr17_-_41521719 0.25 ENST00000393976.6
keratin 15
chrX_+_66164210 0.25 ENST00000343002.7
ENST00000336279.9
hephaestin
chr19_-_43204223 0.24 ENST00000599746.5
pregnancy specific beta-1-glycoprotein 4
chr4_+_40197023 0.24 ENST00000381799.10
ras homolog family member H
chr13_+_73054969 0.23 ENST00000539231.5
Kruppel like factor 5
chr2_-_216013517 0.23 ENST00000263268.11
melanoregulin
chr3_+_187024614 0.23 ENST00000416235.6
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr5_-_160312756 0.23 ENST00000644313.1
cyclin J like
chr5_+_140827950 0.23 ENST00000378126.4
ENST00000529310.6
ENST00000527624.1
protocadherin alpha 6
chr9_-_39239174 0.23 ENST00000358144.6
contactin associated protein family member 3
chr19_-_50953063 0.23 ENST00000391809.6
kallikrein related peptidase 5
chr8_+_49911801 0.23 ENST00000643809.1
syntrophin gamma 1
chr4_-_56821679 0.23 ENST00000504762.1
ENST00000506738.6
ENST00000248701.8
ENST00000616980.1
ENST00000618802.3
ENST00000631082.1
serine peptidase inhibitor Kazal type 2
chr6_+_29301701 0.23 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr19_-_50953093 0.22 ENST00000593428.5
kallikrein related peptidase 5
chr20_+_59835853 0.22 ENST00000492611.5
phosphatase and actin regulator 3
chr19_-_10587219 0.22 ENST00000591240.5
ENST00000589684.5
ENST00000591676.1
ENST00000250244.11
ENST00000590923.5
adaptor related protein complex 1 subunit mu 2
chr4_+_87975667 0.22 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
secreted phosphoprotein 1
chr13_+_31739542 0.22 ENST00000380314.2
relaxin family peptide receptor 2
chr17_-_4739866 0.22 ENST00000574412.6
ENST00000293778.12
C-X-C motif chemokine ligand 16
chr18_+_63587297 0.22 ENST00000269489.9
serpin family B member 13
chr18_+_63587336 0.22 ENST00000344731.10
serpin family B member 13
chr3_-_151329539 0.22 ENST00000325602.6
purinergic receptor P2Y13
chr20_-_57711536 0.22 ENST00000265626.8
prostate transmembrane protein, androgen induced 1
chr2_+_68734773 0.22 ENST00000409202.8
Rho GTPase activating protein 25
chr19_-_50952942 0.22 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr1_-_207032749 0.21 ENST00000359470.6
ENST00000461135.2
chromosome 1 open reading frame 116
chr6_-_136466858 0.21 ENST00000544465.5
microtubule associated protein 7
chr12_-_70637405 0.21 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
protein tyrosine phosphatase receptor type B
chr7_-_80922354 0.21 ENST00000419255.6
semaphorin 3C
chr13_+_31739520 0.21 ENST00000298386.7
relaxin family peptide receptor 2
chr12_+_50924005 0.21 ENST00000550502.1
methyltransferase like 7A
chr6_-_47042306 0.20 ENST00000371253.7
adhesion G protein-coupled receptor F1
chr11_-_55936400 0.20 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr5_+_140875299 0.20 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr7_+_148133684 0.20 ENST00000628930.2
contactin associated protein 2
chr5_+_148202771 0.20 ENST00000514389.5
ENST00000621437.4
serine peptidase inhibitor Kazal type 6
chr4_+_40196907 0.20 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr18_-_31102411 0.20 ENST00000251081.8
ENST00000280904.11
ENST00000682357.1
ENST00000648081.1
desmocollin 2
chr19_-_51028015 0.20 ENST00000319720.11
kallikrein related peptidase 11
chr11_-_102780620 0.20 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr3_-_172523460 0.20 ENST00000420541.6
TNF superfamily member 10
chr9_-_5833014 0.19 ENST00000339450.10
endoplasmic reticulum metallopeptidase 1
chr15_+_94297939 0.19 ENST00000357742.9
multiple C2 and transmembrane domain containing 2
chrX_-_31178149 0.19 ENST00000679437.1
dystrophin
chr2_+_203936755 0.19 ENST00000316386.11
ENST00000435193.1
inducible T cell costimulator
chr5_+_35856883 0.19 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr14_+_21280077 0.19 ENST00000400017.7
RPGR interacting protein 1
chr11_-_112164056 0.19 ENST00000524595.5
interleukin 18
chr11_+_18132565 0.19 ENST00000621697.2
MAS related GPR family member X3
chr11_-_112164080 0.19 ENST00000528832.1
ENST00000280357.12
interleukin 18
chr5_-_16508812 0.19 ENST00000683414.1
reticulophagy regulator 1
chr6_-_32816910 0.19 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chrX_+_106168297 0.19 ENST00000337685.6
ENST00000357175.6
PWWP domain containing 3B
chrX_-_54798253 0.19 ENST00000218436.7
inter-alpha-trypsin inhibitor heavy chain family member 6
chr1_+_61952283 0.19 ENST00000307297.8
PATJ crumbs cell polarity complex component
chr4_+_87975829 0.19 ENST00000614857.5
secreted phosphoprotein 1
chr1_+_61952036 0.19 ENST00000646453.1
ENST00000635137.1
PATJ crumbs cell polarity complex component
chr6_+_36130484 0.19 ENST00000373766.9
ENST00000211287.9
mitogen-activated protein kinase 13
chr16_+_4795357 0.18 ENST00000586005.6
small integral membrane protein 22
chr8_+_31639291 0.18 ENST00000651149.1
ENST00000650866.1
neuregulin 1
chr19_-_42594918 0.18 ENST00000244336.10
CEA cell adhesion molecule 8
chr4_-_88158605 0.18 ENST00000237612.8
ATP binding cassette subfamily G member 2 (Junior blood group)
chr6_-_26216673 0.18 ENST00000541790.3
H2B clustered histone 8
chrX_+_3066833 0.18 ENST00000359361.2
arylsulfatase F
chr5_-_177780845 0.18 ENST00000393518.7
family with sequence similarity 153 member A
chr1_+_61742418 0.18 ENST00000316485.11
ENST00000371158.6
ENST00000642238.2
ENST00000613764.4
PATJ crumbs cell polarity complex component
chr7_-_22194709 0.18 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr8_+_31639222 0.18 ENST00000519301.6
ENST00000652698.1
neuregulin 1
chr2_+_218710931 0.18 ENST00000442769.5
ENST00000424644.1
tubulin tyrosine ligase like 4
chr17_-_41118369 0.18 ENST00000391413.4
keratin associated protein 4-11
chr1_+_34782259 0.18 ENST00000373362.3
gap junction protein beta 3
chr19_-_6767420 0.18 ENST00000245908.11
ENST00000437152.7
ENST00000597687.1
SH2 domain containing 3A
chr18_+_63476927 0.18 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr11_+_5389377 0.17 ENST00000328611.5
olfactory receptor family 51 subfamily M member 1
chr11_-_72793636 0.17 ENST00000538536.5
ENST00000543304.5
ENST00000540587.1
StAR related lipid transfer domain containing 10
chr12_-_52926459 0.17 ENST00000552150.5
keratin 8
chr12_+_41437680 0.17 ENST00000649474.1
ENST00000539469.6
ENST00000298919.7
PDZ domain containing ring finger 4
chr2_+_102311502 0.17 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr1_+_196774813 0.17 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
complement factor H related 3
chr11_+_55811367 0.17 ENST00000625203.2
olfactory receptor family 5 subfamily L member 1
chr6_-_47042260 0.17 ENST00000371243.2
adhesion G protein-coupled receptor F1
chrX_+_66164340 0.17 ENST00000441993.7
ENST00000419594.6
ENST00000425114.2
hephaestin
chr14_-_60169843 0.17 ENST00000536410.6
ENST00000216500.9
dehydrogenase/reductase 7
chr14_+_22226711 0.16 ENST00000390463.3
T cell receptor alpha variable 36/delta variable 7
chr12_+_56338873 0.16 ENST00000228534.6
interleukin 23 subunit alpha
chr19_-_43656616 0.16 ENST00000593447.5
plasminogen activator, urokinase receptor
chr1_-_95072936 0.16 ENST00000370205.6
ALG14 UDP-N-acetylglucosaminyltransferase subunit
chr6_+_111259294 0.16 ENST00000672303.1
ENST00000671876.2
ENST00000368847.5
major facilitator superfamily domain containing 4B
chr3_+_122055355 0.16 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr6_-_28587250 0.16 ENST00000452236.3
zinc finger BED-type containing 9
chr17_-_66229380 0.16 ENST00000205948.11
apolipoprotein H
chr21_-_41926680 0.16 ENST00000329623.11
C2 calcium dependent domain containing 2
chr1_+_152985231 0.16 ENST00000368762.1
small proline rich protein 1A
chr1_+_240014319 0.16 ENST00000447095.5
formin 2
chrX_-_31178220 0.16 ENST00000681026.1
dystrophin
chr10_+_128047559 0.16 ENST00000306042.9
protein tyrosine phosphatase receptor type E
chr3_+_58008350 0.16 ENST00000490882.5
ENST00000358537.7
ENST00000429972.6
ENST00000682871.1
ENST00000295956.9
filamin B
chr1_+_45688165 0.16 ENST00000372025.5
transmembrane protein 69
chr19_+_41797147 0.15 ENST00000596544.1
CEA cell adhesion molecule 3
chr9_-_101384999 0.15 ENST00000259407.7
bile acid-CoA:amino acid N-acyltransferase
chr6_+_24356903 0.15 ENST00000274766.2
kidney associated antigen 1
chr3_-_98522869 0.15 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
claudin domain containing 1
chr7_-_32299287 0.15 ENST00000396193.5
phosphodiesterase 1C
chr11_-_72794032 0.15 ENST00000334805.11
StAR related lipid transfer domain containing 10
chr3_+_112086364 0.15 ENST00000264848.10
chromosome 3 open reading frame 52
chr11_-_124445696 0.15 ENST00000642064.1
olfactory receptor family 8 subfamily B member 8
chr9_-_115091018 0.15 ENST00000542877.5
ENST00000537320.5
ENST00000341037.8
tenascin C
chr3_-_74521140 0.15 ENST00000263665.6
contactin 3
chr3_-_169147734 0.15 ENST00000464456.5
MDS1 and EVI1 complex locus
chr1_+_99970430 0.15 ENST00000370153.6
solute carrier family 35 member A3
chr6_-_30744537 0.15 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr4_+_88378733 0.15 ENST00000273960.7
ENST00000380265.9
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_-_197226351 0.15 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr2_+_218710821 0.15 ENST00000392102.6
ENST00000457313.5
ENST00000415717.5
tubulin tyrosine ligase like 4
chr1_+_99850485 0.15 ENST00000370165.7
ENST00000370163.7
ENST00000294724.8
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr12_+_1970772 0.15 ENST00000682544.1
calcium voltage-gated channel subunit alpha1 C
chr11_+_55635113 0.15 ENST00000641760.1
olfactory receptor family 4 subfamily P member 4
chr14_+_21042352 0.15 ENST00000298690.5
ribonuclease A family member 7
chr1_-_99766620 0.14 ENST00000646001.2
ferric chelate reductase 1
chr12_+_1970809 0.14 ENST00000683781.1
ENST00000682462.1
calcium voltage-gated channel subunit alpha1 C
chr7_-_38249572 0.14 ENST00000436911.6
T cell receptor gamma constant 2
chr11_+_112176364 0.14 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
beta-carotene oxygenase 2
chr3_-_190322434 0.14 ENST00000295522.4
claudin 1
chr7_+_116953482 0.14 ENST00000323984.8
ENST00000417919.5
suppression of tumorigenicity 7
chr11_-_7796942 0.14 ENST00000329434.3
olfactory receptor family 5 subfamily P member 2
chr1_-_10964201 0.14 ENST00000418570.6
chromosome 1 open reading frame 127
chr1_-_153041111 0.14 ENST00000360379.4
small proline rich protein 2D
chr18_+_58149314 0.14 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4 like E3 ubiquitin protein ligase
chr1_+_160739286 0.14 ENST00000359331.8
ENST00000495334.1
SLAM family member 7
chr12_-_10998304 0.14 ENST00000538986.2
taste 2 receptor member 20
chr18_+_58362467 0.14 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr7_+_116953514 0.14 ENST00000446490.5
suppression of tumorigenicity 7
chr21_+_42199686 0.14 ENST00000398457.6
ATP binding cassette subfamily G member 1
chr14_+_96797304 0.14 ENST00000553683.2
ENST00000680538.1
ENST00000681195.1
ENST00000679727.1
ENST00000680509.1
ENST00000557222.6
ENST00000680683.1
ENST00000680335.1
ENST00000216639.8
ENST00000679736.1
ENST00000681176.1
ENST00000557352.2
ENST00000679903.1
ENST00000681419.1
ENST00000680849.1
ENST00000681493.1
ENST00000679770.1
ENST00000681355.1
ENST00000681344.1
VRK serine/threonine kinase 1
chr1_+_15341744 0.14 ENST00000444385.5
forkhead associated phosphopeptide binding domain 1
chr9_-_136245802 0.14 ENST00000358701.10
quiescin sulfhydryl oxidase 2
chr19_+_57830288 0.14 ENST00000442832.8
ENST00000594901.2
zinc finger protein 587B
chr4_+_88378842 0.14 ENST00000264346.12
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr13_+_42781578 0.14 ENST00000313851.3
family with sequence similarity 216 member B
chr16_-_3372666 0.14 ENST00000399974.5
MT-RNR2 like 4
chr4_+_70334963 0.14 ENST00000273936.6
calcium binding protein, spermatid associated 1
chr5_+_136058849 0.14 ENST00000508076.5
transforming growth factor beta induced
chr14_+_64715677 0.14 ENST00000634379.2
pleckstrin homology and RhoGEF domain containing G3
chrX_+_17375230 0.14 ENST00000380060.7
NHS actin remodeling regulator
chrX_+_17375194 0.14 ENST00000676302.1
NHS actin remodeling regulator
chr7_+_116953238 0.14 ENST00000393446.6
suppression of tumorigenicity 7
chr18_+_58196736 0.14 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.4 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 0.4 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.5 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.3 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 0.7 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.3 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.1 0.3 GO:0002445 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.1 0.3 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.4 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.3 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.3 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.5 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.2 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.2 GO:0060057 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.2 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.1 0.2 GO:0016119 carotene metabolic process(GO:0016119)
0.1 0.2 GO:0043016 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.2 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.2 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.0 0.1 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065) cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0009720 detection of hormone stimulus(GO:0009720)
0.0 1.5 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0061580 colon epithelial cell migration(GO:0061580)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.2 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
0.0 0.2 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.4 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.1 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.1 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0036404 conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404)
0.0 1.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0032730 positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.0 0.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.0 0.1 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.0 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0072615 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.0 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.0 0.2 GO:0061709 reticulophagy(GO:0061709)
0.0 0.1 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002580)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.5 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:0048880 sensory system development(GO:0048880)
0.0 0.1 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.5 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.3 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) regulation of serine-type peptidase activity(GO:1902571)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.1 GO:1902164 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 3.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0035739 CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.0 GO:0034627 'de novo' NAD biosynthetic process(GO:0034627)
0.0 1.8 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.0 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.0 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.1 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.0 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.0 GO:1904457 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.0 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.0 GO:1903487 regulation of lactation(GO:1903487)
0.0 0.1 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of T cell migration(GO:2000405) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.0 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0038016 insulin receptor internalization(GO:0038016)
0.0 0.4 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.0 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.0 GO:0060168 regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.1 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.0 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.0 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.0 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.0 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.0 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.0 GO:0035498 carnosine metabolic process(GO:0035498)
0.0 0.0 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 1.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.7 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0071753 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.0 0.1 GO:0033167 ARC complex(GO:0033167)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0071920 cleavage body(GO:0071920)
0.0 0.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.0 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018) MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 1.7 GO:0005549 odorant binding(GO:0005549)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.7 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.2 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.1 0.2 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.2 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 3.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0036505 prosaposin receptor activity(GO:0036505)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.0 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.0 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.0 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.0 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.0 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.0 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.0 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.0 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 2.4 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling