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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for POU5F1_POU2F3

Z-value: 0.75

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
ENSG00000204531.20 POU class 5 homeobox 1
ENSG00000137709.10 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU5F1hg38_v1_chr6_-_31170620_31170698-0.078.7e-01Click!
POU2F3hg38_v1_chr11_+_120240135_120240199,
hg38_v1_chr11_+_120236635_120236642
-0.059.0e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_91946989 1.90 ENST00000556154.5
fibulin 5
chr14_-_91947383 1.66 ENST00000267620.14
fibulin 5
chr12_-_91180365 1.65 ENST00000547937.5
decorin
chr2_+_188974364 1.31 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr19_-_43619591 1.21 ENST00000598676.1
ENST00000300811.8
zinc finger protein 428
chr12_-_91179355 1.08 ENST00000550563.5
ENST00000546370.5
decorin
chrX_+_81202066 1.02 ENST00000373212.6
SH3 domain binding glutamate rich protein like
chr5_+_120531464 1.00 ENST00000505123.5
proline rich 16
chr2_-_187554351 0.99 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr4_+_123399488 0.99 ENST00000394339.2
sprouty RTK signaling antagonist 1
chr4_+_70050431 0.98 ENST00000511674.5
ENST00000246896.8
histatin 1
chr14_-_91947654 0.95 ENST00000342058.9
fibulin 5
chr5_-_111756245 0.90 ENST00000447165.6
neuronal regeneration related protein
chr2_+_240998608 0.88 ENST00000310397.13
sushi, nidogen and EGF like domains 1
chrX_-_107775951 0.84 ENST00000315660.8
ENST00000372384.6
ENST00000502650.1
ENST00000506724.1
TSC22 domain family member 3
chr12_-_91182652 0.79 ENST00000552145.5
ENST00000546745.5
decorin
chr12_-_91182784 0.77 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chrX_-_107717054 0.77 ENST00000503515.1
ENST00000372397.6
TSC22 domain family member 3
chr19_-_49640092 0.76 ENST00000246792.4
RAS related
chr20_+_34704336 0.72 ENST00000374809.6
ENST00000374810.8
ENST00000451665.5
tumor protein p53 inducible nuclear protein 2
chr12_-_91179472 0.63 ENST00000550099.5
ENST00000546391.5
decorin
chr12_+_6943811 0.62 ENST00000544681.1
ENST00000537087.5
chromosome 12 open reading frame 57
chr6_-_35688907 0.62 ENST00000539068.5
ENST00000357266.9
FKBP prolyl isomerase 5
chr12_+_6944009 0.60 ENST00000229281.6
chromosome 12 open reading frame 57
chr9_-_92424427 0.60 ENST00000375550.5
osteomodulin
chr4_-_156970903 0.59 ENST00000422544.2
platelet derived growth factor C
chr5_-_111757175 0.58 ENST00000509025.5
ENST00000257435.12
ENST00000515855.5
neuronal regeneration related protein
chr16_+_32995048 0.54 ENST00000425181.3
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chrX_-_81201886 0.53 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
high mobility group nucleosome binding domain 5
chr12_+_6944065 0.53 ENST00000540506.2
chromosome 12 open reading frame 57
chr1_-_145910066 0.53 ENST00000539363.2
integrin subunit alpha 10
chr1_-_145910031 0.52 ENST00000369304.8
integrin subunit alpha 10
chr1_+_163069353 0.52 ENST00000531057.5
ENST00000527809.5
ENST00000367908.8
ENST00000367909.11
regulator of G protein signaling 4
chr3_+_12351470 0.51 ENST00000287820.10
peroxisome proliferator activated receptor gamma
chr5_-_159099909 0.50 ENST00000313708.11
EBF transcription factor 1
chr2_+_200308943 0.50 ENST00000619961.4
spermatogenesis associated serine rich 2 like
chr2_-_68319887 0.48 ENST00000409862.1
ENST00000263655.4
cannabinoid receptor interacting protein 1
chr17_+_40062810 0.48 ENST00000584985.5
ENST00000264637.8
thyroid hormone receptor alpha
chr4_+_125314918 0.48 ENST00000674496.2
ENST00000394329.9
FAT atypical cadherin 4
chr10_-_77090722 0.46 ENST00000638531.1
potassium calcium-activated channel subfamily M alpha 1
chr1_+_61081728 0.46 ENST00000371189.8
nuclear factor I A
chr3_+_12351493 0.44 ENST00000683699.1
peroxisome proliferator activated receptor gamma
chr21_-_38121331 0.43 ENST00000482032.1
ENST00000398948.5
ENST00000328264.7
ENST00000645093.1
Down syndrome critical region 4
potassium inwardly rectifying channel subfamily J member 6
chr1_+_61077219 0.42 ENST00000407417.7
nuclear factor I A
chr2_-_189179754 0.41 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr7_-_13989658 0.40 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr2_+_151357583 0.39 ENST00000243347.5
TNF alpha induced protein 6
chr13_+_75804221 0.39 ENST00000489941.6
ENST00000525373.5
LIM domain 7
chr22_+_37696982 0.39 ENST00000644935.1
TRIO and F-actin binding protein
chr19_+_14583076 0.38 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chr10_+_31319125 0.38 ENST00000320985.14
ENST00000560721.6
ENST00000558440.5
ENST00000424869.6
ENST00000542815.7
zinc finger E-box binding homeobox 1
chr5_+_93583212 0.37 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr5_-_172771187 0.37 ENST00000239223.4
dual specificity phosphatase 1
chr14_-_106130061 0.36 ENST00000390602.3
immunoglobulin heavy variable 3-13
chr1_+_59310071 0.36 ENST00000371212.5
FGGY carbohydrate kinase domain containing
chr5_-_111976925 0.36 ENST00000395634.7
neuronal regeneration related protein
chr3_-_48556785 0.36 ENST00000232375.8
ENST00000383734.6
ENST00000416568.5
ENST00000412035.5
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr9_-_76906090 0.35 ENST00000376718.8
prune homolog 2 with BCH domain
chr10_+_123148128 0.35 ENST00000339992.4
H6 family homeobox 2
chr20_+_41028814 0.35 ENST00000361337.3
DNA topoisomerase I
chr7_-_13988863 0.35 ENST00000405358.8
ETS variant transcription factor 1
chr1_+_164559739 0.34 ENST00000627490.2
PBX homeobox 1
chr5_+_93584916 0.34 ENST00000647447.1
ENST00000615873.1
nuclear receptor subfamily 2 group F member 1
chr13_+_75804169 0.33 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr12_-_95548213 0.33 ENST00000537435.2
ubiquitin specific peptidase 44
chr19_-_893172 0.33 ENST00000325464.6
ENST00000312090.10
mediator complex subunit 16
chr2_-_178478499 0.32 ENST00000434643.6
FKBP prolyl isomerase 7
chr9_-_76906041 0.32 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
prune homolog 2 with BCH domain
chr2_-_187554473 0.32 ENST00000453013.5
ENST00000417013.5
tissue factor pathway inhibitor
chr17_-_68955332 0.32 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr1_-_243163310 0.31 ENST00000492145.1
ENST00000490813.5
ENST00000464936.5
centrosomal protein 170
chr22_-_28306645 0.31 ENST00000612946.4
tetratricopeptide repeat domain 28
chr19_-_18281612 0.31 ENST00000252818.5
JunD proto-oncogene, AP-1 transcription factor subunit
chr19_-_893200 0.30 ENST00000269814.8
ENST00000395808.7
mediator complex subunit 16
chr5_-_147453888 0.30 ENST00000398514.7
dihydropyrimidinase like 3
chr1_+_103655760 0.29 ENST00000370083.9
amylase alpha 1A
chr6_-_33711684 0.29 ENST00000374231.8
ENST00000607484.6
ubiquinol-cytochrome c reductase complex assembly factor 2
chr20_+_36214373 0.29 ENST00000432603.1
erythrocyte membrane protein band 4.1 like 1
chr11_-_133845495 0.28 ENST00000299140.8
ENST00000532889.1
spermatogenesis associated 19
chr2_-_178478541 0.28 ENST00000424785.7
FKBP prolyl isomerase 7
chr1_+_61082398 0.28 ENST00000664149.1
nuclear factor I A
chr4_-_185812209 0.28 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
sorbin and SH3 domain containing 2
chr19_+_17226662 0.28 ENST00000598068.5
occludin/ELL domain containing 1
chr5_-_173328407 0.28 ENST00000265087.9
stanniocalcin 2
chr11_+_120240135 0.28 ENST00000543440.7
POU class 2 homeobox 3
chr6_-_31684040 0.28 ENST00000375863.7
lymphocyte antigen 6 family member G5C
chr14_-_106088573 0.28 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr9_-_120477354 0.27 ENST00000416449.5
CDK5 regulatory subunit associated protein 2
chr17_-_7404039 0.27 ENST00000576017.1
ENST00000302422.4
transmembrane protein 256
chr2_-_174847015 0.27 ENST00000650938.1
chimerin 1
chr14_+_79279403 0.27 ENST00000281127.11
neurexin 3
chr6_+_71886703 0.27 ENST00000491071.6
regulating synaptic membrane exocytosis 1
chr2_-_174846405 0.26 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr2_-_144517663 0.26 ENST00000427902.5
ENST00000462355.2
ENST00000470879.5
ENST00000409487.7
ENST00000435831.5
ENST00000630572.2
zinc finger E-box binding homeobox 2
chr8_+_69492793 0.26 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
sulfatase 1
chr1_+_164559173 0.26 ENST00000420696.7
PBX homeobox 1
chr16_-_30096170 0.26 ENST00000566134.5
ENST00000565110.5
ENST00000398841.6
ENST00000398838.8
yippee like 3
chr19_+_17226597 0.26 ENST00000597836.5
occludin/ELL domain containing 1
chr8_-_107497909 0.26 ENST00000517746.6
angiopoietin 1
chr17_+_45135640 0.26 ENST00000586346.5
ENST00000321854.13
ENST00000398322.7
ENST00000592162.5
ENST00000376955.8
acyl-CoA binding domain containing 4
chr11_+_64318091 0.26 ENST00000265462.9
ENST00000352435.8
ENST00000347941.4
peroxiredoxin 5
chr6_+_71886900 0.25 ENST00000517960.5
ENST00000518273.5
ENST00000522291.5
ENST00000521978.5
ENST00000520567.5
ENST00000264839.11
regulating synaptic membrane exocytosis 1
chr6_+_27147094 0.25 ENST00000377459.3
H2A clustered histone 12
chr9_-_20382461 0.25 ENST00000380321.5
ENST00000629733.3
MLLT3 super elongation complex subunit
chr6_-_52995170 0.25 ENST00000370959.1
ENST00000370963.9
glutathione S-transferase alpha 4
chr22_+_22704265 0.25 ENST00000390307.2
immunoglobulin lambda variable 3-22
chr19_+_17406099 0.25 ENST00000634942.2
ENST00000634568.1
ENST00000600514.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr19_+_39412650 0.24 ENST00000425673.6
pleckstrin homology and RhoGEF domain containing G2
chr3_-_149576203 0.24 ENST00000472417.1
WW domain containing transcription regulator 1
chr19_+_17226218 0.24 ENST00000601529.5
ENST00000215061.9
ENST00000600232.5
occludin/ELL domain containing 1
chr3_-_112610262 0.24 ENST00000479368.1
coiled-coil domain containing 80
chr10_-_62816341 0.24 ENST00000242480.4
ENST00000637191.1
early growth response 2
chr17_+_57257002 0.24 ENST00000322684.7
ENST00000579590.5
musashi RNA binding protein 2
chr2_-_38076076 0.23 ENST00000614273.1
ENST00000610745.5
ENST00000490576.1
cytochrome P450 family 1 subfamily B member 1
chr2_+_56183973 0.23 ENST00000407595.3
coiled-coil domain containing 85A
chr2_+_112911159 0.23 ENST00000263326.8
interleukin 37
chr11_-_58844484 0.23 ENST00000532258.1
glycine-N-acyltransferase like 2
chr2_-_79086847 0.23 ENST00000454188.5
regenerating family member 1 beta
chr1_+_32200587 0.23 ENST00000373602.10
ENST00000421922.6
ENST00000681230.1
coiled-coil domain containing 28B
chr14_+_79279339 0.23 ENST00000557594.5
neurexin 3
chr1_-_145885826 0.22 ENST00000544626.2
ENST00000355594.9
ankyrin repeat domain 35
chr15_-_63156774 0.22 ENST00000462430.5
ribosomal protein S27 like
chr1_-_160282458 0.22 ENST00000485079.1
novel protein
chr1_+_6555301 0.22 ENST00000333172.11
ENST00000351136.7
taste 1 receptor member 1
chr3_+_148730100 0.22 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr14_+_79279681 0.22 ENST00000679122.1
neurexin 3
chr12_+_59664677 0.22 ENST00000548610.5
solute carrier family 16 member 7
chr4_-_158173042 0.22 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr10_+_94089067 0.22 ENST00000371375.1
ENST00000675218.1
phospholipase C epsilon 1
chr5_+_61332236 0.22 ENST00000252744.6
zinc finger SWIM-type containing 6
chr2_+_209579598 0.22 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr5_+_173918186 0.21 ENST00000657000.1
cytoplasmic polyadenylation element binding protein 4
chr7_+_90709530 0.21 ENST00000406263.5
cyclin dependent kinase 14
chr16_+_21678514 0.21 ENST00000286149.8
ENST00000388958.8
otoancorin
chr10_-_62816309 0.21 ENST00000411732.3
early growth response 2
chr3_+_54123452 0.21 ENST00000620722.4
ENST00000490478.5
calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr1_+_65264694 0.21 ENST00000263441.11
ENST00000395325.7
DnaJ heat shock protein family (Hsp40) member C6
chr15_-_19988117 0.21 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr20_-_62407274 0.21 ENST00000279101.9
Cdk5 and Abl enzyme substrate 2
chr1_+_47333863 0.21 ENST00000471289.2
ENST00000450808.2
cytidine/uridine monophosphate kinase 1
chr1_+_164559766 0.21 ENST00000367897.5
ENST00000559240.5
PBX homeobox 1
chr6_-_33711717 0.21 ENST00000374214.3
ubiquinol-cytochrome c reductase complex assembly factor 2
chr5_+_173918216 0.21 ENST00000519467.1
cytoplasmic polyadenylation element binding protein 4
chr19_+_35358460 0.21 ENST00000327809.5
free fatty acid receptor 3
chr15_-_58065734 0.20 ENST00000347587.7
aldehyde dehydrogenase 1 family member A2
chr15_-_58065870 0.20 ENST00000537372.5
aldehyde dehydrogenase 1 family member A2
chr2_+_219279330 0.20 ENST00000425450.5
ENST00000392086.8
ENST00000421532.5
ENST00000336576.10
DnaJ heat shock protein family (Hsp40) member B2
chr5_-_39425187 0.20 ENST00000545653.5
DAB adaptor protein 2
chr6_-_15586006 0.20 ENST00000462989.6
dystrobrevin binding protein 1
chr12_-_7092422 0.20 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr2_-_40512361 0.20 ENST00000403092.5
solute carrier family 8 member A1
chr6_-_24877262 0.20 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr22_+_22758698 0.20 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr15_-_58065703 0.20 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chr19_+_3572971 0.20 ENST00000453933.5
ENST00000262949.7
high mobility group 20B
chr7_-_151248668 0.20 ENST00000262188.13
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr21_-_10649835 0.20 ENST00000622028.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr19_+_3572777 0.20 ENST00000416526.5
high mobility group 20B
chr19_-_12365628 0.20 ENST00000438182.5
zinc finger protein 442
chr6_-_26033609 0.20 ENST00000615868.2
H2A clustered histone 4
chr4_+_122339221 0.19 ENST00000442707.1
KIAA1109
chr1_+_103749898 0.19 ENST00000622339.5
amylase alpha 1C
chr13_-_42992165 0.19 ENST00000398762.7
ENST00000313640.11
ENST00000313624.12
epithelial stromal interaction 1
chr4_+_133149307 0.19 ENST00000618019.1
protocadherin 10
chr2_+_161231078 0.19 ENST00000439442.1
TRAF family member associated NFKB activator
chr14_-_106593319 0.19 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr7_+_90709231 0.19 ENST00000446790.5
ENST00000265741.7
cyclin dependent kinase 14
chr3_+_141387616 0.19 ENST00000509883.5
zinc finger and BTB domain containing 38
chr12_+_133130618 0.19 ENST00000426665.6
ENST00000248211.11
zinc finger protein 10
chr3_-_187745460 0.19 ENST00000406870.7
BCL6 transcription repressor
chr10_+_81875173 0.19 ENST00000372141.7
ENST00000404547.5
neuregulin 3
chr19_+_926001 0.19 ENST00000263620.8
AT-rich interaction domain 3A
chr14_-_106811131 0.18 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr1_+_192809031 0.18 ENST00000235382.7
regulator of G protein signaling 2
chr12_-_10420550 0.18 ENST00000381903.2
ENST00000396439.7
killer cell lectin like receptor C3
chr14_-_106675544 0.18 ENST00000390632.2
immunoglobulin heavy variable 3-66
chrX_-_136780925 0.18 ENST00000250617.7
Rac/Cdc42 guanine nucleotide exchange factor 6
chr22_-_23754376 0.18 ENST00000398465.3
ENST00000248948.4
V-set pre-B cell surrogate light chain 3
chr6_+_101181254 0.18 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr22_+_43923755 0.18 ENST00000423180.2
ENST00000216180.8
patatin like phospholipase domain containing 3
chr11_+_20022550 0.18 ENST00000533917.5
neuron navigator 2
chr9_+_18474206 0.18 ENST00000276935.6
ADAMTS like 1
chrX_+_12975083 0.18 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr22_+_22818994 0.18 ENST00000390316.2
immunoglobulin lambda variable 3-9
chr22_-_19447686 0.18 ENST00000399568.5
ENST00000399562.9
chromosome 22 open reading frame 39
chr2_-_151261839 0.18 ENST00000331426.6
RNA binding motif protein 43
chr3_-_15797930 0.18 ENST00000683139.1
ankyrin repeat domain 28
chr14_-_106658251 0.17 ENST00000454421.2
immunoglobulin heavy variable 3-64
chr10_+_94089034 0.17 ENST00000676102.1
ENST00000371385.8
phospholipase C epsilon 1
chr2_-_210171402 0.17 ENST00000281772.14
KAT8 regulatory NSL complex subunit 1 like
chr3_-_127822455 0.17 ENST00000265052.10
monoglyceride lipase
chr15_+_67166019 0.17 ENST00000537194.6
SMAD family member 3
chr5_-_160400025 0.17 ENST00000523213.1
ENST00000408953.4
zinc finger BED-type containing 8
chr7_+_130293134 0.17 ENST00000445470.6
ENST00000492072.5
ENST00000222482.10
ENST00000473956.5
ENST00000493259.5
ENST00000486598.1
carboxypeptidase A4
chr1_-_3650063 0.17 ENST00000419924.2
ENST00000270708.12
WD repeat containing, antisense to TP73
chr5_+_172834225 0.17 ENST00000393784.8
endoplasmic reticulum-golgi intermediate compartment 1
chr1_+_248445512 0.17 ENST00000642130.1
ENST00000641925.2
olfactory receptor family 2 subfamily T member 2
chr10_+_80132591 0.17 ENST00000372267.6
placenta associated 9
chr1_-_167090370 0.17 ENST00000367868.4
glycoprotein A33
chr9_+_18474100 0.17 ENST00000327883.11
ENST00000431052.6
ENST00000380570.8
ENST00000380548.9
ADAMTS like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 4.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.0 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 1.7 GO:0021678 third ventricle development(GO:0021678)
0.2 1.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.5 GO:0021658 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1 1.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.0 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.4 GO:0030047 actin modification(GO:0030047)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 0.2 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.4 GO:0019075 virus maturation(GO:0019075)
0.1 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.1 0.3 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.7 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.0 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.3 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.2 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.0 0.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 1.2 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0070476 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.3 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 1.2 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662) sclerotome development(GO:0061056) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0 0.1 GO:0071335 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.1 GO:2000449 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) CD8-positive, alpha-beta T cell extravasation(GO:0035697) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) regulation of T cell extravasation(GO:2000407) positive regulation of monocyte extravasation(GO:2000439) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.2 GO:0048294 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.5 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 1.2 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.4 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0032712 regulation of tolerance induction dependent upon immune response(GO:0002652) negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.0 0.1 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.0 0.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.3 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:2000690 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0070676 regulation of multivesicular body size(GO:0010796) intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
0.0 0.5 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.8 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0061011 gall bladder development(GO:0061010) hepatic duct development(GO:0061011)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.0 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.0 GO:1900212 mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.0 0.5 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.1 GO:0061084 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) negative regulation of protein folding(GO:1903333)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.0 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.0 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.1 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.5 GO:0071953 elastic fiber(GO:0071953)
0.4 5.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.0 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.0 GO:0097444 spine apparatus(GO:0097444)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.6 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.0 GO:0050692 DBD domain binding(GO:0050692)
0.1 1.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.1 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.1 4.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.5 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.2 GO:0016295 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 1.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 3.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0036042 lysophosphatidic acid binding(GO:0035727) long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.0 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.0 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 5.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 2.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 2.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors