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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for PTF1A

Z-value: 0.58

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Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
PTF1A
ENSG00000168267.7 pancreas associated transcription factor 1a

Activity profile of PTF1A motif

Sorted Z-values of PTF1A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_40196907 0.98 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
RHOH
ras homolog family member H
chr4_+_40197023 0.71 ENST00000381799.10
RHOH
ras homolog family member H
chr20_+_46008900 0.66 ENST00000372330.3
MMP9
matrix metallopeptidase 9
chr8_+_32548303 0.59 ENST00000650967.1
NRG1
neuregulin 1
chr8_+_32548210 0.53 ENST00000523079.5
ENST00000650919.1
NRG1
neuregulin 1
chr1_+_26529745 0.40 ENST00000374168.7
ENST00000374166.8
RPS6KA1
ribosomal protein S6 kinase A1
chr10_+_11823348 0.39 ENST00000277570.10
ENST00000622831.4
PROSER2
proline and serine rich 2
chr12_+_112906949 0.31 ENST00000679971.1
ENST00000675868.2
ENST00000550883.2
ENST00000553152.2
ENST00000202917.10
ENST00000679467.1
ENST00000680659.1
ENST00000540589.3
ENST00000552526.2
ENST00000681228.1
ENST00000680934.1
ENST00000681700.1
ENST00000679987.1
OAS1
2'-5'-oligoadenylate synthetase 1
chr8_+_32548267 0.31 ENST00000356819.7
NRG1
neuregulin 1
chr2_-_159904668 0.31 ENST00000504764.5
ENST00000505052.1
ENST00000263636.5
LY75-CD302
LY75
LY75-CD302 readthrough
lymphocyte antigen 75
chr8_-_144416481 0.30 ENST00000276833.9
SLC39A4
solute carrier family 39 member 4
chr8_-_124565699 0.30 ENST00000519168.5
MTSS1
MTSS I-BAR domain containing 1
chr12_+_112906777 0.30 ENST00000452357.7
ENST00000445409.7
OAS1
2'-5'-oligoadenylate synthetase 1
chr7_-_22356914 0.28 ENST00000344041.10
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr12_+_112907006 0.28 ENST00000680455.1
ENST00000551241.6
ENST00000550689.2
ENST00000679841.1
ENST00000679494.1
ENST00000553185.2
OAS1
2'-5'-oligoadenylate synthetase 1
chr8_-_144416819 0.27 ENST00000526658.1
ENST00000301305.8
SLC39A4
solute carrier family 39 member 4
chr2_-_236503688 0.26 ENST00000418802.2
ENST00000431676.6
IQCA1
IQ motif containing with AAA domain 1
chr2_-_71227055 0.24 ENST00000244221.9
PAIP2B
poly(A) binding protein interacting protein 2B
chr7_-_22357112 0.23 ENST00000405243.1
ENST00000665637.1
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr19_+_6464229 0.22 ENST00000600229.6
ENST00000356762.7
CRB3
crumbs cell polarity complex component 3
chr2_+_96760857 0.20 ENST00000377075.3
CNNM4
cyclin and CBS domain divalent metal cation transport mediator 4
chr19_+_6464491 0.20 ENST00000308243.7
CRB3
crumbs cell polarity complex component 3
chr19_+_29665444 0.19 ENST00000592810.1
ENST00000436066.4
PLEKHF1
pleckstrin homology and FYVE domain containing 1
chr19_+_41755520 0.18 ENST00000199764.7
CEACAM6
CEA cell adhesion molecule 6
chr20_+_50731571 0.16 ENST00000371610.7
PARD6B
par-6 family cell polarity regulator beta
chr13_-_31162341 0.16 ENST00000445273.6
ENST00000630972.2
HSPH1
heat shock protein family H (Hsp110) member 1
chr20_+_43916142 0.15 ENST00000423191.6
ENST00000372999.5
TOX2
TOX high mobility group box family member 2
chr18_-_55510753 0.14 ENST00000543082.5
TCF4
transcription factor 4
chr13_-_31161890 0.13 ENST00000320027.10
HSPH1
heat shock protein family H (Hsp110) member 1
chr12_+_50057548 0.13 ENST00000228468.8
ENST00000447966.7
ASIC1
acid sensing ion channel subunit 1
chr7_+_30284574 0.13 ENST00000323037.5
ZNRF2
zinc and ring finger 2
chr14_+_69879408 0.13 ENST00000361956.8
ENST00000381280.4
SMOC1
SPARC related modular calcium binding 1
chr20_-_45631235 0.12 ENST00000326000.2
WFDC9
WAP four-disulfide core domain 9
chr10_+_97572493 0.12 ENST00000307518.9
ENST00000298808.9
ANKRD2
ankyrin repeat domain 2
chr4_+_183905266 0.12 ENST00000308497.9
STOX2
storkhead box 2
chr9_-_101383558 0.11 ENST00000674556.1
BAAT
bile acid-CoA:amino acid N-acyltransferase
chr12_+_12813316 0.11 ENST00000352940.8
ENST00000358007.7
ENST00000544400.1
DDX47
DEAD-box helicase 47
chr15_+_79311084 0.11 ENST00000299705.10
TMED3
transmembrane p24 trafficking protein 3
chr1_-_158330957 0.11 ENST00000451207.5
CD1B
CD1b molecule
chr3_-_112133218 0.11 ENST00000488580.5
ENST00000308910.9
ENST00000460387.6
ENST00000484193.5
ENST00000487901.1
GCSAM
germinal center associated signaling and motility
chr3_+_167735704 0.11 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
SERPINI1
serpin family I member 1
chr2_-_70768175 0.11 ENST00000355733.7
ENST00000447731.6
ENST00000430656.5
ENST00000264436.9
ENST00000413157.6
ADD2
adducin 2
chr1_-_204685700 0.10 ENST00000367177.4
LRRN2
leucine rich repeat neuronal 2
chr12_-_21941300 0.10 ENST00000684084.1
ABCC9
ATP binding cassette subfamily C member 9
chr11_-_104968533 0.10 ENST00000444739.7
CASP4
caspase 4
chr9_+_122519141 0.10 ENST00000340750.1
OR1J4
olfactory receptor family 1 subfamily J member 4
chr1_-_158331522 0.09 ENST00000368168.4
CD1B
CD1b molecule
chr4_+_155666827 0.09 ENST00000511507.5
ENST00000506455.6
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
chr3_-_155745016 0.08 ENST00000460012.7
PLCH1
phospholipase C eta 1
chr6_-_149923077 0.08 ENST00000367360.7
ENST00000479265.1
RAET1G
retinoic acid early transcript 1G
chr6_-_41747390 0.08 ENST00000356667.8
ENST00000373025.7
ENST00000425343.6
PGC
progastricsin
chr4_+_20700436 0.08 ENST00000444671.6
ENST00000510700.5
ENST00000506745.5
ENST00000514663.5
ENST00000509469.5
ENST00000515339.5
ENST00000513861.5
ENST00000502374.5
ENST00000503585.6
ENST00000511160.5
ENST00000504630.5
ENST00000513590.5
ENST00000514292.5
ENST00000502938.5
ENST00000509625.1
ENST00000505160.1
ENST00000507634.5
ENST00000513459.5
ENST00000511089.1
PACRGL
parkin coregulated like
chr19_+_9178979 0.08 ENST00000642043.1
ENST00000641288.2
OR7D2
olfactory receptor family 7 subfamily D member 2
chr17_+_41249687 0.08 ENST00000334109.3
KRTAP9-4
keratin associated protein 9-4
chr2_+_85695368 0.08 ENST00000526018.1
GNLY
granulysin
chr1_+_230979064 0.07 ENST00000366658.6
ENST00000310256.7
ENST00000450711.5
ENST00000435927.5
ARV1
ARV1 homolog, fatty acid homeostasis modulator
chr1_+_9997220 0.07 ENST00000294435.8
RBP7
retinol binding protein 7
chr12_-_48004467 0.07 ENST00000380518.8
COL2A1
collagen type II alpha 1 chain
chr22_-_17159220 0.07 ENST00000399852.3
ENST00000336737.8
HDHD5
haloacid dehalogenase like hydrolase domain containing 5
chr7_+_150991087 0.07 ENST00000461406.5
NOS3
nitric oxide synthase 3
chr19_+_11559429 0.07 ENST00000585493.5
ZNF627
zinc finger protein 627
chr17_+_42844573 0.06 ENST00000253799.8
ENST00000452774.2
AOC2
amine oxidase copper containing 2
chr19_+_18340629 0.06 ENST00000597431.2
PGPEP1
pyroglutamyl-peptidase I
chr21_+_33205279 0.06 ENST00000683941.1
IFNAR2
interferon alpha and beta receptor subunit 2
chr12_+_112013418 0.06 ENST00000261735.4
ENST00000552052.1
ERP29
endoplasmic reticulum protein 29
chr8_-_98294339 0.06 ENST00000341166.3
NIPAL2
NIPA like domain containing 2
chr16_-_46689145 0.06 ENST00000299138.12
VPS35
VPS35 retromer complex component
chr14_-_76826229 0.06 ENST00000557497.1
ANGEL1
angel homolog 1
chr12_-_21941402 0.06 ENST00000326684.8
ENST00000682068.1
ENST00000621589.2
ENST00000261200.9
ENST00000683676.1
ABCC9
ATP binding cassette subfamily C member 9
chr3_-_52835011 0.06 ENST00000446157.3
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr1_+_12125892 0.06 ENST00000413146.6
TNFRSF8
TNF receptor superfamily member 8
chr8_-_98294195 0.06 ENST00000430223.7
NIPAL2
NIPA like domain containing 2
chr5_-_75717368 0.06 ENST00000514838.6
ENST00000506164.5
ENST00000502826.5
ENST00000428202.7
ENST00000503835.5
POC5
POC5 centriolar protein
chr1_+_100038087 0.06 ENST00000370152.8
MFSD14A
major facilitator superfamily domain containing 14A
chr12_+_112013348 0.06 ENST00000455836.1
ERP29
endoplasmic reticulum protein 29
chr14_-_106875069 0.05 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr19_-_42442938 0.05 ENST00000601181.6
CXCL17
C-X-C motif chemokine ligand 17
chr5_+_141177790 0.05 ENST00000239444.4
ENST00000623995.1
PCDHB8
ENSG00000279472.1
protocadherin beta 8
novel transcript
chr4_+_155666718 0.05 ENST00000621234.4
ENST00000511108.5
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
chr8_+_49911396 0.05 ENST00000642720.2
SNTG1
syntrophin gamma 1
chrX_-_44542833 0.05 ENST00000378045.5
FUNDC1
FUN14 domain containing 1
chr4_-_86357722 0.05 ENST00000641341.1
ENST00000642038.1
ENST00000641116.1
ENST00000641767.1
ENST00000639242.1
ENST00000638313.1
MAPK10
mitogen-activated protein kinase 10
chr16_+_71358713 0.05 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
CALB2
calbindin 2
chr12_-_14938508 0.05 ENST00000266397.7
ERP27
endoplasmic reticulum protein 27
chr1_+_200739542 0.05 ENST00000358823.6
CAMSAP2
calmodulin regulated spectrin associated protein family member 2
chr11_+_64291285 0.05 ENST00000422670.7
ENST00000538767.1
KCNK4
potassium two pore domain channel subfamily K member 4
chr10_+_48684859 0.05 ENST00000360890.6
ENST00000325239.11
WDFY4
WDFY family member 4
chr19_-_5867741 0.05 ENST00000252675.6
FUT5
fucosyltransferase 5
chr9_-_135961310 0.05 ENST00000371756.4
UBAC1
UBA domain containing 1
chr11_+_6863057 0.05 ENST00000641461.1
OR10A2
olfactory receptor family 10 subfamily A member 2
chr17_-_41098084 0.05 ENST00000318329.6
ENST00000333822.5
KRTAP4-8
keratin associated protein 4-8
chr2_+_119429889 0.05 ENST00000409826.1
ENST00000417645.1
TMEM37
transmembrane protein 37
chr13_-_79405784 0.04 ENST00000267229.11
RBM26
RNA binding motif protein 26
chr13_+_112979306 0.04 ENST00000421756.5
MCF2L
MCF.2 cell line derived transforming sequence like
chr7_-_37916807 0.04 ENST00000436072.7
SFRP4
secreted frizzled related protein 4
chr3_-_50359480 0.04 ENST00000266025.4
TMEM115
transmembrane protein 115
chr2_+_218880844 0.04 ENST00000258411.8
WNT10A
Wnt family member 10A
chr17_+_38297023 0.04 ENST00000619548.1
ENST00000613675.5
MRPL45
mitochondrial ribosomal protein L45
chr20_-_46513516 0.04 ENST00000347606.8
ENST00000625284.2
ENST00000457685.6
ZNF334
zinc finger protein 334
chr3_-_52834901 0.04 ENST00000486659.5
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr12_+_30926716 0.04 ENST00000546076.6
ENST00000535215.5
ENST00000261177.10
TSPAN11
tetraspanin 11
chr1_-_9069608 0.04 ENST00000377424.9
SLC2A5
solute carrier family 2 member 5
chr3_+_35679690 0.04 ENST00000413378.5
ENST00000417925.5
ARPP21
cAMP regulated phosphoprotein 21
chr2_-_196068812 0.04 ENST00000410072.5
ENST00000312428.11
DNAH7
dynein axonemal heavy chain 7
chr7_-_152676130 0.04 ENST00000359321.2
XRCC2
X-ray repair cross complementing 2
chr8_-_109648825 0.04 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
SYBU
syntabulin
chr10_+_75111595 0.04 ENST00000671800.1
ENST00000542569.6
ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr14_-_58427134 0.04 ENST00000555930.6
TIMM9
translocase of inner mitochondrial membrane 9
chr16_+_46884675 0.04 ENST00000562132.5
ENST00000440783.2
GPT2
glutamic--pyruvic transaminase 2
chr11_-_102705737 0.03 ENST00000260229.5
MMP27
matrix metallopeptidase 27
chr19_-_10380454 0.03 ENST00000530829.1
ENST00000529370.5
TYK2
tyrosine kinase 2
chr1_-_44141631 0.03 ENST00000634670.1
KLF18
Kruppel like factor 18
chr7_-_5513738 0.03 ENST00000453700.7
ENST00000382368.8
FBXL18
F-box and leucine rich repeat protein 18
chr11_+_71527267 0.03 ENST00000398536.6
KRTAP5-7
keratin associated protein 5-7
chrX_-_11665908 0.03 ENST00000337414.9
ARHGAP6
Rho GTPase activating protein 6
chr22_+_24603147 0.03 ENST00000412658.5
ENST00000445029.5
ENST00000400382.6
ENST00000419133.5
ENST00000438643.6
ENST00000452551.5
ENST00000412898.5
ENST00000400380.5
ENST00000455483.5
ENST00000430289.5
GGT1
gamma-glutamyltransferase 1
chr17_+_55264952 0.03 ENST00000226067.10
HLF
HLF transcription factor, PAR bZIP family member
chr3_-_12841527 0.03 ENST00000396953.6
ENST00000457131.1
ENST00000435983.5
ENST00000273223.10
ENST00000429711.7
ENST00000396957.5
RPL32
ribosomal protein L32
chr15_-_72231113 0.03 ENST00000565154.6
ENST00000565184.6
ENST00000335181.10
PKM
pyruvate kinase M1/2
chr3_+_57060658 0.03 ENST00000334325.2
SPATA12
spermatogenesis associated 12
chr14_-_58427158 0.03 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
TIMM9
translocase of inner mitochondrial membrane 9
chr4_-_82798735 0.03 ENST00000273908.4
ENST00000319540.9
SCD5
stearoyl-CoA desaturase 5
chr7_-_88795732 0.03 ENST00000297203.3
TEX47
testis expressed 47
chr15_-_72231583 0.03 ENST00000566809.1
ENST00000567087.5
ENST00000569050.1
ENST00000568883.5
PKM
pyruvate kinase M1/2
chr12_+_93571664 0.02 ENST00000622746.4
ENST00000548537.1
SOCS2
suppressor of cytokine signaling 2
chr22_-_50085331 0.02 ENST00000395876.6
MLC1
modulator of VRAC current 1
chr20_-_3663399 0.02 ENST00000290417.7
ENST00000319242.8
GFRA4
GDNF family receptor alpha 4
chr19_+_54573781 0.02 ENST00000391738.8
ENST00000251376.7
ENST00000391737.3
ENST00000629481.1
LILRA2
leukocyte immunoglobulin like receptor A2
chr15_+_79311137 0.02 ENST00000424155.6
ENST00000536821.5
TMED3
transmembrane p24 trafficking protein 3
chr11_-_45665578 0.02 ENST00000308064.7
CHST1
carbohydrate sulfotransferase 1
chr12_-_57251169 0.02 ENST00000554578.5
ENST00000546246.2
ENST00000332782.7
ENST00000553489.1
STAC3
SH3 and cysteine rich domain 3
chr3_+_35639515 0.02 ENST00000684406.1
ARPP21
cAMP regulated phosphoprotein 21
chr1_-_75611083 0.02 ENST00000370855.5
SLC44A5
solute carrier family 44 member 5
chr3_+_35679614 0.02 ENST00000474696.5
ENST00000412048.5
ENST00000396482.6
ENST00000432682.5
ARPP21
cAMP regulated phosphoprotein 21
chr2_+_172735838 0.02 ENST00000397081.8
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr1_-_45491150 0.02 ENST00000372086.4
TESK2
testis associated actin remodelling kinase 2
chr15_-_89221558 0.02 ENST00000268125.10
RLBP1
retinaldehyde binding protein 1
chr17_-_41149823 0.02 ENST00000343246.6
KRTAP4-5
keratin associated protein 4-5
chr1_+_39738866 0.02 ENST00000324379.10
ENST00000356511.6
ENST00000497370.5
ENST00000470213.5
ENST00000372835.9
ENST00000372830.5
PPIE
peptidylprolyl isomerase E
chr14_-_56816693 0.02 ENST00000673035.1
OTX2
orthodenticle homeobox 2
chr8_-_134712962 0.02 ENST00000523399.5
ENST00000377838.8
ZFAT
zinc finger and AT-hook domain containing
chr19_-_9219589 0.02 ENST00000641244.1
ENST00000641669.1
OR7D4
olfactory receptor family 7 subfamily D member 4
chr3_-_155293665 0.01 ENST00000489090.2
STRIT1
small transmembrane regulator of ion transport 1
chr14_-_106025628 0.01 ENST00000631943.1
IGHV7-4-1
immunoglobulin heavy variable 7-4-1
chr4_+_155666963 0.01 ENST00000455639.6
GUCY1A1
guanylate cyclase 1 soluble subunit alpha 1
chr12_+_51888217 0.01 ENST00000340970.8
ANKRD33
ankyrin repeat domain 33
chr12_+_51888083 0.01 ENST00000301190.11
ANKRD33
ankyrin repeat domain 33
chr17_+_51165435 0.01 ENST00000514264.6
NME2
NME/NM23 nucleoside diphosphate kinase 2
chr1_-_9069572 0.01 ENST00000377414.7
SLC2A5
solute carrier family 2 member 5
chr14_-_58427114 0.01 ENST00000556007.6
TIMM9
translocase of inner mitochondrial membrane 9
chr6_-_159044980 0.01 ENST00000367066.8
TAGAP
T cell activation RhoGTPase activating protein
chr2_+_97646034 0.01 ENST00000258424.3
COX5B
cytochrome c oxidase subunit 5B
chrX_-_21658324 0.01 ENST00000379499.3
KLHL34
kelch like family member 34
chr3_+_126524319 0.01 ENST00000615522.1
CHST13
carbohydrate sulfotransferase 13
chr17_+_41105332 0.01 ENST00000391415.1
ENST00000617453.1
KRTAP4-9
keratin associated protein 4-9
chr1_-_75611109 0.01 ENST00000370859.7
SLC44A5
solute carrier family 44 member 5
chr9_-_33025088 0.01 ENST00000436040.7
APTX
aprataxin
chr6_-_159045104 0.01 ENST00000326965.7
TAGAP
T cell activation RhoGTPase activating protein
chr1_+_157993601 0.01 ENST00000359209.11
KIRREL1
kirre like nephrin family adhesion molecule 1
chr17_-_35986649 0.01 ENST00000622526.1
ENST00000620991.1
ENST00000618404.5
CCL14
C-C motif chemokine ligand 14
chr7_-_5967204 0.00 ENST00000337579.4
RSPH10B
radial spoke head 10 homolog B
chr12_+_56996151 0.00 ENST00000556850.1
GPR182
G protein-coupled receptor 182
chr19_-_39840671 0.00 ENST00000597224.5
FBL
fibrillarin
chr12_-_57846686 0.00 ENST00000548823.1
ENST00000398073.7
CTDSP2
CTD small phosphatase 2
chr17_+_7014745 0.00 ENST00000546760.5
ENST00000552402.5
C17orf49
chromosome 17 open reading frame 49
chr2_-_86195400 0.00 ENST00000442664.6
ENST00000409051.6
ENST00000410111.8
ENST00000620815.4
ENST00000449247.6
IMMT
inner membrane mitochondrial protein

Network of associatons between targets according to the STRING database.

First level regulatory network of PTF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 1.4 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.7 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.1 GO:1903179 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
0.1 0.3 GO:0030035 microspike assembly(GO:0030035)
0.1 0.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 1.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.2 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.0 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.0 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.1 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 GO:0030673 axolemma(GO:0030673)
0.0 1.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.0 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.0 0.1 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.0 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions