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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for RELB

Z-value: 0.78

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Transcription factors associated with RELB

Gene Symbol Gene ID Gene Info
ENSG00000104856.14 RELB proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELBhg38_v1_chr19_+_45001430_450015250.946.3e-04Click!

Activity profile of RELB motif

Sorted Z-values of RELB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_23949847 1.40 ENST00000588004.1
laminin subunit alpha 3
chr12_-_8662619 1.37 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr12_-_8662703 1.33 ENST00000535336.5
microfibril associated protein 5
chr6_-_136526177 1.02 ENST00000617204.4
microtubule associated protein 7
chr11_+_18266254 1.00 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr6_-_136526472 0.94 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr12_-_57767057 0.87 ENST00000228606.9
cytochrome P450 family 27 subfamily B member 1
chr6_-_136525961 0.85 ENST00000438100.6
microtubule associated protein 7
chr12_-_8662808 0.71 ENST00000359478.7
ENST00000396549.6
microfibril associated protein 5
chr1_-_186680411 0.67 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr18_+_36297661 0.65 ENST00000257209.8
ENST00000590592.5
ENST00000359247.8
formin homology 2 domain containing 3
chr12_-_85836372 0.65 ENST00000361228.5
Ras association domain family member 9
chr7_+_86643902 0.61 ENST00000361669.7
glutamate metabotropic receptor 3
chr1_+_24319511 0.60 ENST00000356046.6
grainyhead like transcription factor 3
chr2_+_162318884 0.57 ENST00000446271.5
ENST00000429691.6
grancalcin
chr2_-_162318475 0.53 ENST00000648433.1
interferon induced with helicase C domain 1
chr1_+_24319342 0.51 ENST00000361548.9
grainyhead like transcription factor 3
chr19_-_4338786 0.50 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
signal transducing adaptor family member 2
chr18_+_58149314 0.50 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4 like E3 ubiquitin protein ligase
chr15_-_78944985 0.47 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
cathepsin H
chr1_-_24187246 0.47 ENST00000374421.7
ENST00000374418.3
ENST00000327575.6
ENST00000327535.6
interferon lambda receptor 1
chr11_+_34621065 0.46 ENST00000257831.8
ETS homologous factor
chr3_+_113947901 0.46 ENST00000330212.7
ENST00000498275.5
zinc finger DHHC-type palmitoyltransferase 23
chr11_+_72114840 0.44 ENST00000622388.4
folate receptor gamma
chr12_+_56079843 0.43 ENST00000549282.5
ENST00000549061.5
ENST00000683059.1
erb-b2 receptor tyrosine kinase 3
chr6_+_137867241 0.43 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr6_-_11779606 0.42 ENST00000506810.1
androgen dependent TFPI regulating protein
chr12_+_82686889 0.42 ENST00000321196.8
transmembrane O-mannosyltransferase targeting cadherins 2
chr12_-_8662881 0.42 ENST00000433590.6
microfibril associated protein 5
chr6_+_137867414 0.42 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr6_+_14117764 0.42 ENST00000379153.4
CD83 molecule
chr6_+_116461364 0.40 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr19_+_14031746 0.40 ENST00000263379.4
interleukin 27 receptor subunit alpha
chr5_-_16508951 0.39 ENST00000682628.1
reticulophagy regulator 1
chr5_-_16508858 0.39 ENST00000684456.1
reticulophagy regulator 1
chr5_-_16508812 0.38 ENST00000683414.1
reticulophagy regulator 1
chr3_+_113948004 0.37 ENST00000638807.2
zinc finger DHHC-type palmitoyltransferase 23
chr12_-_12562851 0.36 ENST00000298573.9
dual specificity phosphatase 16
chr5_-_16508990 0.35 ENST00000399793.6
reticulophagy regulator 1
chr15_+_90184912 0.35 ENST00000561085.1
ENST00000332496.10
semaphorin 4B
chr5_-_16508788 0.34 ENST00000682142.1
reticulophagy regulator 1
chr1_-_32901330 0.34 ENST00000329151.5
ENST00000373463.8
transmembrane protein 54
chr1_-_112711355 0.34 ENST00000606505.5
ENST00000605933.5
novel protein, PPM1J-RHOC readthrough
chr19_+_45001430 0.33 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr1_-_183590876 0.33 ENST00000367536.5
neutrophil cytosolic factor 2
chr16_-_57284654 0.32 ENST00000613167.4
ENST00000219207.10
ENST00000569059.5
plasmolipin
chr11_+_34621109 0.32 ENST00000450654.6
ETS homologous factor
chr8_+_100158576 0.31 ENST00000388798.7
sperm associated antigen 1
chr11_+_102317492 0.31 ENST00000673846.1
baculoviral IAP repeat containing 3
chr4_+_102501885 0.30 ENST00000505458.5
nuclear factor kappa B subunit 1
chr2_+_112977998 0.30 ENST00000259205.5
ENST00000376489.6
interleukin 36 gamma
chr21_+_45455514 0.30 ENST00000355480.10
ENST00000359759.8
collagen type XVIII alpha 1 chain
chr8_-_80171106 0.29 ENST00000519303.6
tumor protein D52
chr2_+_64454506 0.28 ENST00000409537.2
galectin like
chr12_-_12562344 0.27 ENST00000228862.3
dual specificity phosphatase 16
chr8_-_65842051 0.26 ENST00000401827.8
phosphodiesterase 7A
chr12_+_6946468 0.25 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr1_+_37474572 0.25 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr10_-_71773513 0.25 ENST00000394957.8
V-set immunoregulatory receptor
chr2_+_158968608 0.24 ENST00000263635.8
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chrX_-_24647091 0.24 ENST00000356768.8
phosphate cytidylyltransferase 1, choline, beta
chr1_+_156153568 0.24 ENST00000368284.5
ENST00000368286.6
ENST00000368285.8
ENST00000438830.5
semaphorin 4A
chr1_-_6261053 0.23 ENST00000377893.3
G protein-coupled receptor 153
chr7_-_22500152 0.22 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP family member 1B
chr2_+_26346086 0.22 ENST00000613142.4
ENST00000260585.12
ENST00000447170.1
selenoprotein I
chr6_+_29723340 0.22 ENST00000334668.8
major histocompatibility complex, class I, F
chr16_+_2009870 0.22 ENST00000567649.1
neuropeptide W
chr2_-_88947820 0.22 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr1_+_45688165 0.22 ENST00000372025.5
transmembrane protein 69
chr3_-_161104816 0.22 ENST00000417187.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr2_+_60881515 0.22 ENST00000295025.12
REL proto-oncogene, NF-kB subunit
chr4_+_73869385 0.21 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr1_-_205775449 0.21 ENST00000235932.8
ENST00000437324.6
ENST00000414729.1
ENST00000367139.8
RAB29, member RAS oncogene family
chr2_-_162318613 0.21 ENST00000649979.2
ENST00000421365.2
interferon induced with helicase C domain 1
chr3_+_50205254 0.21 ENST00000614032.5
ENST00000445096.5
solute carrier family 38 member 3
chr8_+_22053543 0.20 ENST00000519850.5
ENST00000381470.7
dematin actin binding protein
chr19_+_40717091 0.20 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr17_+_7380534 0.20 ENST00000570896.5
tyrosine kinase non receptor 1
chr11_-_124441158 0.20 ENST00000328064.2
olfactory receptor family 8 subfamily B member 8
chr10_+_102394488 0.20 ENST00000369966.8
nuclear factor kappa B subunit 2
chr3_-_52056552 0.20 ENST00000495880.2
dual specificity phosphatase 7
chr14_-_35404650 0.20 ENST00000553342.1
ENST00000557140.5
ENST00000216797.10
NFKB inhibitor alpha
chr2_+_60881553 0.19 ENST00000394479.4
REL proto-oncogene, NF-kB subunit
chrX_-_20266606 0.19 ENST00000643085.1
ENST00000645270.1
ENST00000644368.1
ribosomal protein S6 kinase A3
chr6_+_29723421 0.19 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr1_+_156149657 0.19 ENST00000414683.5
semaphorin 4A
chr4_-_184474518 0.19 ENST00000393593.8
interferon regulatory factor 2
chr1_-_205775182 0.19 ENST00000446390.6
RAB29, member RAS oncogene family
chr6_-_10838467 0.19 ENST00000313243.6
male germ cell associated kinase
chr6_-_24358036 0.19 ENST00000378454.8
doublecortin domain containing 2
chr14_+_23372809 0.18 ENST00000397242.2
ENST00000329715.2
interleukin 25
chr14_+_103123452 0.18 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr6_-_10838503 0.18 ENST00000536370.6
ENST00000474039.5
ENST00000354489.7
ENST00000676116.1
male germ cell associated kinase
chr19_-_4831689 0.18 ENST00000248244.6
toll like receptor adaptor molecule 1
chr10_+_132397168 0.18 ENST00000631148.2
ENST00000305233.6
PWWP domain containing 2B
chr15_+_85380625 0.18 ENST00000560302.5
A-kinase anchoring protein 13
chr1_+_23791138 0.17 ENST00000374514.8
ENST00000420982.5
ENST00000374505.6
lysophospholipase 2
chr11_+_33376077 0.17 ENST00000658780.2
KIAA1549 like
chr16_+_2019777 0.17 ENST00000566435.4
neuropeptide W
chr7_-_111562455 0.16 ENST00000452895.5
ENST00000405709.7
ENST00000452753.1
ENST00000331762.7
inner mitochondrial membrane peptidase subunit 2
chr4_-_73998669 0.16 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr6_+_29942523 0.16 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr20_+_9514562 0.16 ENST00000246070.3
lysosomal associated membrane protein family member 5
chr11_+_102317542 0.15 ENST00000532808.5
baculoviral IAP repeat containing 3
chr15_-_30991415 0.15 ENST00000563714.5
myotubularin related protein 10
chr4_+_77605807 0.15 ENST00000682537.1
C-X-C motif chemokine ligand 13
chr14_+_91114431 0.15 ENST00000428926.6
ENST00000517362.5
D-glutamate cyclase
chr12_+_6199715 0.15 ENST00000382518.6
ENST00000642746.1
ENST00000538834.6
CD9 molecule
chr16_+_50696999 0.15 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr3_+_6861107 0.15 ENST00000357716.9
ENST00000486284.5
ENST00000389336.8
glutamate metabotropic receptor 7
chr1_-_1421302 0.14 ENST00000520296.5
ankyrin repeat domain 65
chr14_+_102777555 0.14 ENST00000539721.5
ENST00000560463.5
TNF receptor associated factor 3
chr21_-_41953997 0.14 ENST00000380486.4
C2 calcium dependent domain containing 2
chr2_+_64453969 0.14 ENST00000464281.5
galectin like
chr10_+_18659382 0.14 ENST00000377275.4
ADP ribosylation factor like GTPase 5B
chr12_-_54981838 0.13 ENST00000316577.12
thymocyte expressed, positive selection associated 1
chr11_+_102317450 0.13 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
baculoviral IAP repeat containing 3
chr17_-_76551174 0.13 ENST00000589145.1
cytoglobin
chr14_+_91114364 0.13 ENST00000518868.5
D-glutamate cyclase
chrX_+_51406947 0.13 ENST00000342995.4
EZH inhibitory protein
chr6_+_15248855 0.13 ENST00000397311.4
jumonji and AT-rich interaction domain containing 2
chr9_-_32526185 0.13 ENST00000379883.3
ENST00000379868.6
ENST00000679859.1
DExD/H-box helicase 58
chr15_+_34102037 0.13 ENST00000397766.4
piggyBac transposable element derived 4
chr14_+_102777461 0.13 ENST00000560371.5
ENST00000347662.8
TNF receptor associated factor 3
chr16_-_2009797 0.13 ENST00000563630.6
ENST00000562103.2
zinc finger protein 598, E3 ubiquitin ligase
chr12_+_2053545 0.13 ENST00000682336.1
ENST00000344100.7
ENST00000399591.5
ENST00000399595.5
ENST00000399597.5
ENST00000399601.5
ENST00000399606.5
ENST00000399621.5
ENST00000399629.5
ENST00000399637.5
ENST00000399638.5
ENST00000399644.5
ENST00000399649.5
ENST00000402845.7
ENST00000682686.1
calcium voltage-gated channel subunit alpha1 C
chr17_-_48722510 0.13 ENST00000290294.5
PRAC1 small nuclear protein
chr11_-_5154757 0.13 ENST00000380367.3
olfactory receptor family 52 subfamily A member 1
chr8_-_33567118 0.12 ENST00000256257.2
ring finger protein 122
chr17_-_6556447 0.12 ENST00000421306.7
PITPNM family member 3
chr2_+_165572329 0.12 ENST00000342316.8
cysteine and serine rich nuclear protein 3
chr20_-_4815100 0.12 ENST00000379376.2
Ras association domain family member 2
chr22_-_40819324 0.12 ENST00000435456.7
ENST00000434185.1
ENST00000544408.5
solute carrier family 25 member 17
chr18_+_46946821 0.12 ENST00000245121.9
ENST00000356157.12
katanin catalytic subunit A1 like 2
chr1_-_204411804 0.12 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr12_+_100473916 0.12 ENST00000549996.5
nuclear receptor subfamily 1 group H member 4
chr1_+_46247684 0.12 ENST00000463715.5
ENST00000442598.5
ENST00000493985.5
ENST00000671528.1
RAD54 like
chr1_-_155990062 0.12 ENST00000462460.6
Rho/Rac guanine nucleotide exchange factor 2
chr6_-_29559724 0.11 ENST00000377050.5
ubiquitin D
chr1_+_202010575 0.11 ENST00000367283.7
ENST00000367284.10
E74 like ETS transcription factor 3
chr6_+_135181268 0.11 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr19_-_40716869 0.11 ENST00000677018.1
ENST00000324464.8
ENST00000594720.6
ENST00000677496.1
coenzyme Q8B
chr6_+_5261497 0.11 ENST00000274680.9
phenylalanyl-tRNA synthetase 2, mitochondrial
chr1_+_156642108 0.11 ENST00000457777.6
ENST00000329117.10
ENST00000424639.5
brevican
chr8_-_17002327 0.11 ENST00000180166.6
fibroblast growth factor 20
chr5_-_88883701 0.11 ENST00000636998.1
myocyte enhancer factor 2C
chr7_+_123845048 0.10 ENST00000488323.5
ENST00000223026.9
hyaluronidase 4
chr16_-_74985070 0.10 ENST00000616369.4
ENST00000262144.11
WD repeat domain 59
chr16_+_30023198 0.10 ENST00000681219.1
ENST00000300575.6
chromosome 16 open reading frame 92
chr14_+_102777433 0.10 ENST00000392745.8
TNF receptor associated factor 3
chr2_+_233693659 0.10 ENST00000406651.1
UDP glucuronosyltransferase family 1 member A6
chr1_+_23791203 0.10 ENST00000374503.7
ENST00000374502.7
lysophospholipase 2
chr22_-_37984534 0.10 ENST00000396884.8
SRY-box transcription factor 10
chr1_+_46247731 0.10 ENST00000371975.9
ENST00000469835.6
RAD54 like
chr16_-_66925526 0.10 ENST00000299759.11
ENST00000420652.5
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr14_+_22829879 0.10 ENST00000355151.9
ENST00000397496.7
ENST00000555345.5
ENST00000432849.7
ENST00000553711.5
ENST00000556465.5
ENST00000397505.2
ENST00000557221.1
ENST00000556840.5
ENST00000555536.1
mitochondrial ribosomal protein L52
chr10_+_122461545 0.10 ENST00000368984.8
HtrA serine peptidase 1
chr1_+_25338294 0.10 ENST00000374358.5
transmembrane protein 50A
chr15_-_40307910 0.09 ENST00000543785.3
ENST00000260402.8
phospholipase C beta 2
chr12_-_121580954 0.09 ENST00000536437.5
ENST00000611216.4
ENST00000538046.6
ENST00000377071.9
lysine demethylase 2B
chr12_-_124989053 0.09 ENST00000308736.7
DEAH-box helicase 37
chr12_+_103930332 0.09 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
heat shock protein 90 beta family member 1
chr5_+_141177790 0.09 ENST00000239444.4
ENST00000623995.1
protocadherin beta 8
novel transcript
chr1_+_53894181 0.09 ENST00000361921.8
ENST00000322679.10
ENST00000613679.4
ENST00000617230.2
ENST00000610607.4
ENST00000532493.5
ENST00000525202.5
ENST00000524406.5
ENST00000388876.3
iodothyronine deiodinase 1
chr1_+_161258738 0.09 ENST00000504449.2
Purkinje cell protein 4 like 1
chr4_-_46124046 0.09 ENST00000295452.5
gamma-aminobutyric acid type A receptor subunit gamma1
chr1_-_153540694 0.09 ENST00000368717.2
S100 calcium binding protein A5
chr20_-_34303345 0.09 ENST00000217426.7
adenosylhomocysteinase
chr12_-_117099434 0.09 ENST00000541210.5
tescalcin
chr1_+_151047699 0.09 ENST00000368926.6
chromosome 1 open reading frame 56
chr9_-_127755243 0.09 ENST00000629203.2
ENST00000420366.5
SH2 domain containing 3C
chr12_-_117099384 0.09 ENST00000335209.12
tescalcin
chr14_+_52267683 0.09 ENST00000306051.3
ENST00000553372.1
prostaglandin D2 receptor
chr4_-_74099187 0.09 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr4_-_78939352 0.09 ENST00000512733.5
progestin and adipoQ receptor family member 3
chr21_+_33403466 0.09 ENST00000405436.5
interferon gamma receptor 2
chr17_+_12665882 0.08 ENST00000425538.6
myocardin
chr8_-_123274255 0.08 ENST00000622816.2
ENST00000395571.8
ZHX1-C8orf76 readthrough
zinc fingers and homeoboxes 1
chr7_+_69599588 0.08 ENST00000403018.3
activator of transcription and developmental regulator AUTS2
chr2_+_89913982 0.08 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr5_-_151080978 0.08 ENST00000520931.5
ENST00000521591.6
ENST00000520695.5
ENST00000610535.5
ENST00000518977.5
ENST00000389378.6
ENST00000610874.4
TNFAIP3 interacting protein 1
chr5_+_141199555 0.08 ENST00000624887.1
ENST00000354757.5
protocadherin beta 11
chr1_+_42463221 0.08 ENST00000654683.1
ENST00000667205.1
ENST00000655164.1
ENST00000657597.1
ENST00000667947.1
ENST00000668663.1
ENST00000660083.1
ENST00000655845.1
ENST00000671281.1
ENST00000664805.1
ENST00000654604.1
ENST00000655447.1
ENST00000661864.1
ENST00000665176.1
ENST00000670982.1
ENST00000668036.1
coiled-coil domain containing 30
chr9_+_38392694 0.08 ENST00000377698.4
ENST00000635162.1
aldehyde dehydrogenase 1 family member B1
chr12_+_2053311 0.08 ENST00000399617.6
ENST00000683482.1
calcium voltage-gated channel subunit alpha1 C
chr17_-_79009731 0.08 ENST00000392446.10
ENST00000590370.5
ENST00000591625.5
calcium activated nucleotidase 1
chr6_+_138161932 0.08 ENST00000251691.5
ARFGEF family member 3
chrX_+_48786578 0.08 ENST00000376670.9
GATA binding protein 1
chr16_-_70289480 0.08 ENST00000261772.13
ENST00000675953.1
ENST00000675691.1
ENST00000675133.1
ENST00000674512.1
ENST00000675045.1
ENST00000675853.1
ENST00000565361.3
ENST00000674963.1
ENST00000674691.1
alanyl-tRNA synthetase 1
chr2_-_100104530 0.08 ENST00000432037.5
ENST00000673232.1
ENST00000423966.6
ENST00000409236.6
AF4/FMR2 family member 3
chr17_-_40665121 0.08 ENST00000394052.5
keratin 222
chr5_+_151212117 0.08 ENST00000523466.5
GM2 ganglioside activator
chr7_-_102616692 0.07 ENST00000521076.5
ENST00000462172.5
ENST00000522801.5
ENST00000262940.12
ENST00000449970.6
RAS p21 protein activator 4
chrX_-_11665908 0.07 ENST00000337414.9
Rho GTPase activating protein 6
chr14_+_91114026 0.07 ENST00000521081.5
ENST00000520328.5
ENST00000524232.5
ENST00000522170.5
ENST00000256324.15
ENST00000519950.5
ENST00000523879.5
ENST00000521077.6
ENST00000518665.6
D-glutamate cyclase
chr8_+_49911604 0.07 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr8_+_106726012 0.07 ENST00000449762.6
ENST00000297447.10
oxidation resistance 1
chr14_+_88824621 0.07 ENST00000622513.4
ENST00000380656.7
ENST00000338104.10
ENST00000346301.8
ENST00000354441.10
ENST00000556651.5
ENST00000554686.5
tetratricopeptide repeat domain 8
chr11_+_61248122 0.07 ENST00000451616.6
pepsinogen A5
chr5_+_127649018 0.07 ENST00000379445.7
cortexin 3

Network of associatons between targets according to the STRING database.

First level regulatory network of RELB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.3 0.8 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.2 1.8 GO:0061709 reticulophagy(GO:0061709)
0.2 0.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.9 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.5 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 4.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.2 GO:0089709 histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.5 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.1 1.0 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 1.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.2 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.8 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 0.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:0098706 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.4 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.2 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 1.0 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.4 GO:0015884 folic acid transport(GO:0015884)
0.0 0.5 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0001079 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.4 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.4 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.0 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.1 GO:0071206 establishment of protein localization to juxtaparanode region of axon(GO:0071206)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0010607 negative regulation of cytoplasmic mRNA processing body assembly(GO:0010607)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 2.6 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.5 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.0 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.0 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0005610 laminin-5 complex(GO:0005610)
0.2 3.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 0.5 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 1.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 2.8 GO:0005875 microtubule associated complex(GO:0005875)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.7 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.4 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.5 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:1901474 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 1.0 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0005542 folic acid binding(GO:0005542)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.0 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 2.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 3.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets