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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for RFX3_RFX2

Z-value: 1.37

Motif logo

Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
ENSG00000080298.16 regulatory factor X3
ENSG00000087903.13 regulatory factor X2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX2hg38_v1_chr19_-_6110463_6110541-0.334.3e-01Click!
RFX3hg38_v1_chr9_-_3525968_35260170.265.4e-01Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_5500997 1.94 ENST00000568641.2
novel protein
chr14_+_105474781 1.87 ENST00000550577.5
ENST00000538259.2
ENST00000329146.9
cysteine rich protein 2
chr14_-_59870752 1.78 ENST00000611068.1
ENST00000267484.10
reticulon 1
chr5_+_93583212 1.65 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr1_+_183636065 1.65 ENST00000304685.8
ral guanine nucleotide dissociation stimulator like 1
chr5_-_180353317 1.31 ENST00000253778.13
glutamine-fructose-6-phosphate transaminase 2
chr11_+_134069060 1.27 ENST00000534549.5
ENST00000441717.3
ENST00000299106.9
junctional adhesion molecule 3
chr8_+_119416427 1.22 ENST00000259526.4
cellular communication network factor 3
chr15_+_43510945 1.07 ENST00000382031.5
microtubule associated protein 1A
chr22_-_43089375 1.06 ENST00000266254.12
tubulin tyrosine ligase like 1
chr11_-_70717994 1.04 ENST00000659264.1
SH3 and multiple ankyrin repeat domains 2
chr2_-_175005357 1.03 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr16_+_8712943 1.01 ENST00000561870.5
ENST00000396600.6
4-aminobutyrate aminotransferase
chr10_+_102419189 1.00 ENST00000432590.5
F-box and leucine rich repeat protein 15
chr20_+_44531817 0.95 ENST00000372889.5
ENST00000372887.5
cAMP-dependent protein kinase inhibitor gamma
chr20_+_44531758 0.93 ENST00000372891.7
ENST00000372892.7
ENST00000372894.7
cAMP-dependent protein kinase inhibitor gamma
chr2_+_241869722 0.91 ENST00000343216.3
receptor transporter protein 5 (putative)
chr8_+_17027230 0.89 ENST00000318063.10
mitochondrial calcium uptake family member 3
chr19_+_35140022 0.88 ENST00000588081.5
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr12_-_62935117 0.88 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr1_-_109113818 0.86 ENST00000369949.8
chromosome 1 open reading frame 194
chr6_+_112087576 0.85 ENST00000368656.7
ENST00000604268.1
family with sequence similarity 229 member B
chr1_+_42463221 0.84 ENST00000654683.1
ENST00000667205.1
ENST00000655164.1
ENST00000657597.1
ENST00000667947.1
ENST00000668663.1
ENST00000660083.1
ENST00000655845.1
ENST00000671281.1
ENST00000664805.1
ENST00000654604.1
ENST00000655447.1
ENST00000661864.1
ENST00000665176.1
ENST00000670982.1
ENST00000668036.1
coiled-coil domain containing 30
chr14_+_75578589 0.84 ENST00000238667.9
FLVCR heme transporter 2
chr3_-_197949869 0.80 ENST00000452735.1
ENST00000453254.5
ENST00000455191.5
IQ motif containing G
chr1_+_244969976 0.80 ENST00000366522.6
EF-hand calcium binding domain 2
chr17_-_66191855 0.79 ENST00000583358.1
ENST00000392769.6
centrosomal protein 112
chr16_+_29812230 0.79 ENST00000300797.7
ENST00000637403.1
ENST00000572820.2
ENST00000637064.1
ENST00000636246.1
proline rich transmembrane protein 2
chr7_+_150368189 0.79 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr3_-_58577367 0.77 ENST00000464064.5
ENST00000360997.7
family with sequence similarity 107 member A
chr14_+_99793375 0.77 ENST00000262233.11
ENST00000556714.5
EMAP like 1
chr14_+_99793329 0.77 ENST00000334192.8
EMAP like 1
chr13_-_43786889 0.77 ENST00000261488.10
ecto-NOX disulfide-thiol exchanger 1
chr16_+_29812150 0.76 ENST00000647876.1
ENST00000567551.2
ENST00000567659.3
ENST00000637565.1
ENST00000358758.12
ENST00000636619.1
proline rich transmembrane protein 2
chr17_-_66192125 0.73 ENST00000535342.7
centrosomal protein 112
chr7_-_50782853 0.73 ENST00000401949.6
growth factor receptor bound protein 10
chr19_+_35138993 0.73 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr1_-_48472166 0.73 ENST00000371847.8
ENST00000396199.7
spermatogenesis associated 6
chrX_+_86714623 0.73 ENST00000484479.1
dachshund family transcription factor 2
chr2_+_74421721 0.73 ENST00000409791.5
ENST00000348227.4
WD repeat domain 54
chr7_+_150368790 0.72 ENST00000397281.6
ENST00000444957.3
ENST00000466559.1
ENST00000475514.5
ENST00000482680.1
ENST00000488943.1
ENST00000489432.7
ENST00000518514.1
ENST00000478789.5
replication initiator 1
zinc finger protein 775
chr7_+_101154445 0.71 ENST00000337619.11
ENST00000429457.1
adaptor related protein complex 1 subunit sigma 1
chrX_+_136169891 0.71 ENST00000449474.5
four and a half LIM domains 1
chr8_+_13566854 0.71 ENST00000297324.5
chromosome 8 open reading frame 48
chr3_-_58577648 0.71 ENST00000394481.5
family with sequence similarity 107 member A
chr5_+_149141817 0.70 ENST00000504238.5
actin binding LIM protein family member 3
chr1_+_37556913 0.70 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr6_+_30557274 0.70 ENST00000376557.3
proline rich 3
chr19_+_35139724 0.69 ENST00000588715.5
ENST00000588607.5
FXYD domain containing ion transport regulator 1
chr12_+_48183602 0.69 ENST00000316554.5
coiled-coil domain containing 184
chr2_+_219279330 0.69 ENST00000425450.5
ENST00000392086.8
ENST00000421532.5
ENST00000336576.10
DnaJ heat shock protein family (Hsp40) member B2
chr18_-_3013114 0.69 ENST00000677752.1
lipin 2
chr14_-_73714361 0.67 ENST00000316836.5
PNMA family member 1
chrX_+_136169664 0.65 ENST00000456445.5
four and a half LIM domains 1
chr6_+_30557287 0.65 ENST00000376560.8
proline rich 3
chrX_+_136169833 0.65 ENST00000628032.2
four and a half LIM domains 1
chr15_+_55408479 0.64 ENST00000569691.2
chromosome 15 open reading frame 65
chr11_-_6405405 0.64 ENST00000608645.5
ENST00000618005.4
ENST00000610474.4
ENST00000608394.5
ENST00000529519.5
amyloid beta precursor protein binding family B member 1
chr1_-_48472007 0.63 ENST00000371843.7
spermatogenesis associated 6
chr2_-_202871253 0.63 ENST00000435143.5
islet cell autoantigen 1 like
chr1_+_161098320 0.62 ENST00000368011.9
ENST00000392192.6
kelch domain containing 9
chr2_-_130144994 0.61 ENST00000457413.1
ENST00000409128.5
ENST00000441670.1
ENST00000409234.3
ENST00000409943.8
ENST00000392984.7
ENST00000310463.10
coiled-coil domain containing 74B
chr10_+_12349533 0.61 ENST00000619168.5
calcium/calmodulin dependent protein kinase ID
chr3_-_196712194 0.61 ENST00000399942.4
ENST00000409690.5
centrosomal protein 19
chr15_-_52679347 0.61 ENST00000566768.5
ENST00000561543.5
ENST00000619572.5
family with sequence similarity 214 member A
chr2_+_131527833 0.59 ENST00000295171.10
ENST00000467992.6
ENST00000409856.8
coiled-coil domain containing 74A
chr7_-_140924699 0.59 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
B-Raf proto-oncogene, serine/threonine kinase
chr22_-_30667795 0.59 ENST00000404885.5
ENST00000403268.1
ENST00000407308.1
ENST00000334679.4
ENST00000342474.4
dual specificity phosphatase 18
chr10_+_122271292 0.59 ENST00000260723.6
BTB domain containing 16
chr19_+_35139440 0.58 ENST00000455515.6
FXYD domain containing ion transport regulator 1
chr12_+_51424965 0.58 ENST00000514353.7
solute carrier family 4 member 8
chr19_-_50025936 0.57 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr3_+_48465811 0.54 ENST00000433541.1
ENST00000444177.1
three prime repair exonuclease 1
chr20_+_3888915 0.54 ENST00000316562.9
ENST00000495692.5
pantothenate kinase 2
chr17_-_16569169 0.53 ENST00000395824.5
zinc finger protein 287
chr3_+_48466222 0.53 ENST00000625293.3
ENST00000492235.2
ENST00000635452.2
ENST00000456089.1
three prime repair exonuclease 1
chr14_+_23555983 0.52 ENST00000404535.3
thiamine triphosphatase
chr20_+_11892493 0.52 ENST00000422390.5
ENST00000618918.4
BTB domain containing 3
chr14_+_51847145 0.51 ENST00000615906.4
G protein subunit gamma 2
chr6_+_52420107 0.51 ENST00000636489.1
ENST00000637089.1
ENST00000637353.1
ENST00000637263.1
EF-hand domain containing 1
chrX_+_136169624 0.51 ENST00000394153.6
four and a half LIM domains 1
chr3_-_196318170 0.50 ENST00000325318.10
dynein light chain Tctex-type 2B
chr17_-_16569184 0.50 ENST00000448349.2
ENST00000395825.4
zinc finger protein 287
chr4_-_185812209 0.50 ENST00000393523.6
ENST00000393528.7
ENST00000449407.6
sorbin and SH3 domain containing 2
chr17_-_28335421 0.50 ENST00000578122.5
ENST00000579419.5
ENST00000585313.5
ENST00000578985.5
ENST00000577498.1
ENST00000585089.5
ENST00000357896.7
ENST00000395418.8
ENST00000588477.5
intraflagellar transport 20
chrX_+_103918872 0.50 ENST00000419165.5
thymosin beta 15B
chr5_+_154858218 0.49 ENST00000523698.5
ENST00000517876.5
ENST00000520472.5
CCR4-NOT transcription complex subunit 8
chr6_+_52420332 0.49 ENST00000636107.1
ENST00000371068.11
ENST00000636702.1
ENST00000635996.1
ENST00000636379.1
EF-hand domain containing 1
chr19_+_1266653 0.48 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chrX_+_48597482 0.48 ENST00000218056.9
ENST00000376729.10
WD repeat domain 13
chr19_-_6393205 0.47 ENST00000595047.5
general transcription factor IIF subunit 1
chr16_+_3500964 0.47 ENST00000574369.5
ENST00000576634.6
ENST00000341633.9
ENST00000571025.5
clusterin associated protein 1
chr12_+_8914525 0.47 ENST00000543824.5
polyhomeotic homolog 1
chr17_+_68512379 0.47 ENST00000392711.5
ENST00000585427.5
ENST00000589228.6
ENST00000536854.6
ENST00000588702.5
ENST00000589309.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr7_+_102433519 0.46 ENST00000356387.6
ENST00000478730.7
ENST00000495936.7
ENST00000611770.5
ENST00000403646.8
ORAI calcium release-activated calcium modulator 2
chr9_-_128656649 0.46 ENST00000372715.7
dynein 2 intermediate chain 2
chr17_+_410306 0.46 ENST00000360127.7
ENST00000571106.1
ENST00000491373.1
chromosome 17 open reading frame 97
chr14_+_23556253 0.46 ENST00000556015.5
ENST00000554970.1
ENST00000288014.7
ENST00000554789.1
thiamine triphosphatase
chr1_+_3624978 0.45 ENST00000378344.7
ENST00000344579.5
tumor protein p63 regulated 1 like
chr6_-_41735557 0.45 ENST00000373033.6
transcription factor EB
chr6_-_41736239 0.45 ENST00000358871.6
transcription factor EB
chr5_-_134367144 0.44 ENST00000265334.9
cyclin dependent kinase like 3
chr4_+_113292838 0.44 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr19_-_13938371 0.44 ENST00000588872.3
ENST00000339560.10
podocan like 1
chr12_+_4562192 0.43 ENST00000543431.5
dual specificity tyrosine phosphorylation regulated kinase 4
chr12_+_53295506 0.43 ENST00000549759.2
ENST00000628881.2
ENST00000351500.7
ENST00000550846.5
ENST00000334478.9
ENST00000547130.6
ENST00000552742.6
prefoldin subunit 5
chr22_-_44498179 0.43 ENST00000341255.4
retrotransposon Gag like 6
chr11_+_46936710 0.43 ENST00000378618.6
ENST00000278460.12
ENST00000395460.6
ENST00000378615.7
chromosome 11 open reading frame 49
chr22_+_38656627 0.43 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
chibby family member 1, beta catenin antagonist
chr16_+_4734519 0.43 ENST00000299320.10
chromosome 16 open reading frame 71
chr12_-_109573482 0.43 ENST00000540016.5
ENST00000545712.7
metabolism of cobalamin associated B
chr3_-_16264891 0.43 ENST00000488423.2
ENST00000383775.4
diphthamide biosynthesis 3
chr17_+_68511981 0.42 ENST00000358598.6
protein kinase cAMP-dependent type I regulatory subunit alpha
chr19_+_3572971 0.42 ENST00000453933.5
ENST00000262949.7
high mobility group 20B
chr1_-_118185157 0.42 ENST00000336338.10
sperm associated antigen 17
chr19_-_13937991 0.42 ENST00000254320.7
ENST00000586075.1
podocan like 1
chr4_+_113292925 0.42 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr15_-_55408245 0.42 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
cell cycle progression 1
chr1_-_36450279 0.42 ENST00000445843.7
organic solute carrier partner 1
chr19_+_3572777 0.41 ENST00000416526.5
high mobility group 20B
chr8_+_38386303 0.41 ENST00000519476.6
leucine zipper and EF-hand containing transmembrane protein 2
chr3_-_108222362 0.40 ENST00000492106.1
intraflagellar transport 57
chr5_-_160370619 0.40 ENST00000652664.2
ENST00000393975.4
C1q and TNF related 2
chr7_-_44189428 0.40 ENST00000673284.1
ENST00000403799.8
ENST00000671824.1
glucokinase
chr17_-_19362732 0.40 ENST00000395616.7
B9 domain containing 1
chr3_-_149971109 0.40 ENST00000239940.11
profilin 2
chr11_+_111937320 0.40 ENST00000440460.7
DIX domain containing 1
chr3_+_9809948 0.40 ENST00000426895.9
tubulin tyrosine ligase like 3
chr6_-_27472681 0.39 ENST00000377419.1
zinc finger protein 184
chr12_+_56118241 0.39 ENST00000551790.5
ENST00000552345.1
ENST00000257940.7
ENST00000551880.1
extended synaptotagmin 1
zinc finger CCCH-type containing 10
chr2_+_55519610 0.39 ENST00000406691.7
ENST00000407816.7
ENST00000349456.9
ENST00000403007.4
cilia and flagella associated protein 36
chr6_+_35259703 0.39 ENST00000373953.8
ENST00000339411.5
zinc finger protein 76
chr5_-_134367070 0.39 ENST00000521118.5
cyclin dependent kinase like 3
chr20_+_58907981 0.38 ENST00000656419.1
GNAS complex locus
chr3_-_50345665 0.38 ENST00000442887.1
ENST00000231749.8
ENST00000360165.7
zinc finger MYND-type containing 10
chr16_+_57245336 0.38 ENST00000562023.5
ENST00000563234.1
ADP ribosylation factor like GTPase 2 binding protein
chr4_+_153152163 0.38 ENST00000676423.1
ENST00000675745.1
ENST00000676348.1
ENST00000676408.1
ENST00000674874.1
ENST00000675315.1
ENST00000675518.1
tripartite motif containing 2
novel protein
chr1_-_36450410 0.38 ENST00000356637.9
ENST00000354267.3
ENST00000235532.9
organic solute carrier partner 1
chr21_+_39445824 0.38 ENST00000380637.7
ENST00000380634.5
ENST00000458295.5
ENST00000440288.6
ENST00000380631.5
SH3 domain binding glutamate rich protein
chr6_-_27473058 0.38 ENST00000683788.1
ENST00000211936.10
zinc finger protein 184
chr2_+_38875962 0.38 ENST00000340556.11
ENST00000410014.5
ENST00000644631.3
ENST00000409665.5
ENST00000409077.2
ENST00000409131.2
MORN repeat containing 2
chr12_+_6904733 0.38 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr15_-_64989435 0.38 ENST00000433215.6
ENST00000558415.5
ENST00000557795.5
SPG21 abhydrolase domain containing, maspardin
chr5_-_81751085 0.38 ENST00000515395.5
single stranded DNA binding protein 2
chr16_+_57245229 0.38 ENST00000219204.8
ADP ribosylation factor like GTPase 2 binding protein
chr22_+_37051731 0.37 ENST00000610767.4
ENST00000402077.7
ENST00000403888.7
potassium channel tetramerization domain containing 17
chr16_+_4734457 0.37 ENST00000590191.1
chromosome 16 open reading frame 71
chr12_+_51424802 0.37 ENST00000453097.7
solute carrier family 4 member 8
chr17_-_78903193 0.37 ENST00000322630.3
ENST00000586713.5
CEP295 N-terminal like
chr19_-_46471407 0.37 ENST00000438932.2
PNMA family member 8A
chr2_-_74421560 0.37 ENST00000612891.4
ENST00000640331.1
ENST00000684111.1
chromosome 2 open reading frame 81
chr9_+_35829217 0.37 ENST00000439587.6
ENST00000643932.2
ENST00000650015.1
ENST00000377991.9
transmembrane protein 8B
chr11_-_66336396 0.36 ENST00000627248.1
ENST00000311320.9
Ras and Rab interactor 1
chr19_-_46471484 0.36 ENST00000313683.15
ENST00000602246.1
PNMA family member 8A
chr15_-_43510571 0.36 ENST00000263801.7
tumor protein p53 binding protein 1
chr15_-_64989894 0.36 ENST00000416889.6
ENST00000204566.7
SPG21 abhydrolase domain containing, maspardin
chr8_-_100106034 0.36 ENST00000360863.11
ENST00000617334.1
regulator of G protein signaling 22
chr2_+_55519586 0.36 ENST00000339012.7
cilia and flagella associated protein 36
chr9_+_97307645 0.35 ENST00000529487.3
coiled-coil domain containing 180
chr19_+_17302854 0.35 ENST00000594999.1
mitochondrial ribosomal protein L34
chr17_-_54968697 0.35 ENST00000571584.1
cytochrome c oxidase copper chaperone COX11
chr11_+_66593194 0.35 ENST00000310190.8
copper chaperone for superoxide dismutase
chr5_-_81751022 0.34 ENST00000509013.2
ENST00000505980.5
ENST00000509053.5
single stranded DNA binding protein 2
chr22_+_37051787 0.34 ENST00000456470.1
potassium channel tetramerization domain containing 17
chr6_-_30556477 0.34 ENST00000376621.8
G protein nucleolar 1 (putative)
chr2_-_152175715 0.34 ENST00000263904.5
signal transducing adaptor molecule 2
chr11_+_121024072 0.34 ENST00000529397.5
ENST00000683345.1
ENST00000422003.6
tubulin folding cofactor E like
chr4_+_122732652 0.34 ENST00000542236.5
ENST00000314218.8
Bardet-Biedl syndrome 12
chr14_+_71320421 0.34 ENST00000381232.8
signal induced proliferation associated 1 like 1
chr7_-_1138219 0.33 ENST00000397098.8
ENST00000357429.10
ENST00000397100.6
ENST00000491163.1
chromosome 7 open reading frame 50
chr6_-_43510686 0.33 ENST00000372441.1
leucine rich repeat containing 73
chr17_+_45241067 0.33 ENST00000587489.5
formin like 1
chr19_+_50376447 0.33 ENST00000253727.10
ENST00000598168.5
ENST00000411902.6
ENST00000597790.5
ENST00000597130.5
ENST00000599105.5
nuclear receptor subfamily 1 group H member 2
chr20_-_38260725 0.33 ENST00000279024.9
ENST00000496900.2
KIAA1755
chr8_+_58553216 0.33 ENST00000447182.6
ENST00000413219.6
ENST00000424270.6
ENST00000523483.5
ENST00000520168.5
ENST00000260130.9
syndecan binding protein
chr17_-_15341577 0.32 ENST00000543896.1
ENST00000395930.6
ENST00000539245.5
ENST00000539316.1
tektin 3
chr11_-_67504252 0.32 ENST00000533391.5
ENST00000534749.5
ENST00000532703.5
phosphatidylinositol transfer protein membrane associated 1
chr17_-_54968637 0.32 ENST00000299335.8
cytochrome c oxidase copper chaperone COX11
chr12_-_54259531 0.32 ENST00000550411.5
ENST00000439541.6
chromobox 5
chr15_-_55408467 0.32 ENST00000310958.10
cell cycle progression 1
chrX_-_132489842 0.32 ENST00000436215.5
muscleblind like splicing regulator 3
chr3_-_108222383 0.32 ENST00000264538.4
intraflagellar transport 57
chr10_-_132331818 0.32 ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
serine/threonine kinase 32C
chr19_-_50025327 0.32 ENST00000594092.5
ENST00000594948.5
ENST00000316763.8
ENST00000377011.6
ENST00000593919.5
ENST00000601324.1
ENST00000601341.5
ENST00000600259.5
VRK serine/threonine kinase 3
chr9_+_34329495 0.32 ENST00000346365.8
ENST00000379155.9
ENST00000618590.1
nudix hydrolase 2
chr9_+_34329545 0.31 ENST00000379158.7
nudix hydrolase 2
chr12_+_8914464 0.31 ENST00000544916.6
polyhomeotic homolog 1
chr2_+_237085875 0.31 ENST00000392008.6
ENST00000409334.5
ENST00000354371.7
COP9 signalosome subunit 8
chr16_+_89658025 0.31 ENST00000611218.1
ENST00000568929.1
spermatogenesis associated 33
chr12_-_48106042 0.31 ENST00000551798.1
ENST00000549518.6
SUMO specific peptidase 1
chr11_+_66510626 0.31 ENST00000526815.5
ENST00000318312.12
ENST00000525809.5
ENST00000455748.6
ENST00000393994.4
ENST00000630659.2
Bardet-Biedl syndrome 1
chr20_+_63272785 0.31 ENST00000519273.6
ENST00000519604.5
ENST00000523114.5
ENST00000547204.5
ENST00000549047.5
ENST00000523460.5
ENST00000370283.9
ENST00000370275.8
ADP ribosylation factor GTPase activating protein 1
chr7_-_101321723 0.30 ENST00000498704.6
ENST00000517481.5
ENST00000437644.2
ENST00000315322.10
ENST00000621899.4
intraflagellar transport 22
chr9_+_94084458 0.30 ENST00000620992.5
ENST00000288976.3
protein tyrosine phosphatase domain containing 1
chr14_+_74019341 0.30 ENST00000394009.5
ENST00000464394.5
basal body orientation factor 1
chr3_-_49018558 0.30 ENST00000441576.6
ENST00000420952.2
ENST00000341949.9
DALR anticodon binding domain containing 3
chr2_+_108449178 0.30 ENST00000309863.11
ENST00000409821.5
GRIP and coiled-coil domain containing 2
chr5_-_81751103 0.30 ENST00000514493.5
ENST00000320672.8
ENST00000615665.4
single stranded DNA binding protein 2
chr14_-_20305932 0.30 ENST00000258821.8
ENST00000553828.1
tetratricopeptide repeat domain 5
chr14_+_102362931 0.30 ENST00000359520.12
tectonin beta-propeller repeat containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.3 1.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.3 2.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.3 1.2 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.2 0.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 0.6 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 2.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 1.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 1.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.7 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.5 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.6 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.4 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.3 GO:1902269 putrescine transport(GO:0015847) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.7 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 1.0 GO:0015886 heme transport(GO:0015886)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.4 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 1.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 2.6 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.3 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.1 0.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 1.5 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.1 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.3 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.2 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.2 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.3 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.6 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.5 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.5 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0051365 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.0 0.5 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 1.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.2 GO:0097680 maintenance of Golgi location(GO:0051684) double-strand break repair via classical nonhomologous end joining(GO:0097680) positive regulation of autophagosome maturation(GO:1901098)
0.0 0.9 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 1.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 2.3 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0032425 positive regulation of mismatch repair(GO:0032425)
0.0 0.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.8 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.0 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 1.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.4 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.7 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0034092 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.7 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.3 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 1.0 GO:0006298 mismatch repair(GO:0006298)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.0 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0032792 negative regulation of triglyceride biosynthetic process(GO:0010868) negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.7 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.3 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.0 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.0 GO:1902953 endoplasmic reticulum membrane organization(GO:0090158) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.1 GO:0061525 hindgut development(GO:0061525)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.6 GO:0061013 regulation of mRNA catabolic process(GO:0061013)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.0 GO:0018032 protein amidation(GO:0018032)
0.0 0.0 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0097224 sperm connecting piece(GO:0097224)
0.3 1.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 0.6 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.4 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 2.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.3 GO:0097545 axonemal outer doublet(GO:0097545)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 1.3 GO:0033010 paranodal junction(GO:0033010)
0.1 1.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.0 GO:0005883 neurofilament(GO:0005883)
0.1 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 2.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.9 GO:0034464 BBSome(GO:0034464)
0.1 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 1.2 GO:0043034 costamere(GO:0043034)
0.0 0.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.4 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 1.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 1.3 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.3 0.3 GO:0005119 smoothened binding(GO:0005119)
0.3 1.2 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.2 1.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 1.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.9 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.1 1.4 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.6 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.8 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.9 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.6 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.3 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 0.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.0 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.4 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.3 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.3 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.3 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.0 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 3.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.6 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:1901612 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 3.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.9 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 1.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein