Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
RFX5 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000143390.18	regulatory factor X5

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RFX5	hg38_v1_chr1_-_151347234_151347326	0.88	3.8e-03	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr6_+_32854179 Show fit	0.30	ENST00000374859.3	PSMB9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome 20S subunit beta 9
chr19_+_44914833 Show fit	0.29	ENST00000589078.1 ENST00000586638.5	APOC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein C1
chr19_+_44914702 Show fit	0.26	ENST00000592885.5 ENST00000589781.1	APOC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein C1
chr6_+_33075952 Show fit	0.26	ENST00000418931.7	HLA-DPB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class II, DP beta 1
chr6_+_32844789 Show fit	0.24	ENST00000414474.5	PSMB9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome 20S subunit beta 9
chr6_+_26402237 Show fit	0.19	ENST00000476549.6 ENST00000450085.6 ENST00000425234.6 ENST00000427334.5 ENST00000506698.1 ENST00000289361.11	BTN3A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin subfamily 3 member A1
chr6_+_26402289 Show fit	0.16	ENST00000414912.2	BTN3A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin subfamily 3 member A1
chr6_+_26440472 Show fit	0.15	ENST00000494393.5 ENST00000482451.5 ENST00000471353.5 ENST00000361232.7 ENST00000487627.5 ENST00000496719.1 ENST00000244519.7 ENST00000490254.5 ENST00000487272.1	BTN3A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin subfamily 3 member A3
chr6_-_32844643 Show fit	0.12	ENST00000374881.3	PSMB8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proteasome 20S subunit beta 8
chr6_-_32530268 Show fit	0.12	ENST00000374975.4	HLA-DRB5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class II, DR beta 5
chr6_-_32589833 Show fit	0.12	ENST00000360004.5	HLA-DRB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class II, DR beta 1
chr3_-_169869833 Show fit	0.10	ENST00000523069.1 ENST00000264676.9 ENST00000316428.10	LRRC31 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 31
chr6_+_26365176 Show fit	0.09	ENST00000377708.7	BTN3A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin subfamily 3 member A2
chr6_+_26365159 Show fit	0.09	ENST00000532865.5 ENST00000396934.7 ENST00000508906.6 ENST00000530653.5 ENST00000527417.5	BTN3A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin subfamily 3 member A2
chr6_+_26365215 Show fit	0.09	ENST00000527422.5 ENST00000356386.6 ENST00000396948.5	BTN3A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin subfamily 3 member A2
chr17_-_19362732 Show fit	0.09	ENST00000395616.7	B9D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	B9 domain containing 1
chr1_+_85062304 Show fit	0.08	ENST00000326813.12 ENST00000528899.5 ENST00000294664.11	DNAI3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein axonemal intermediate chain 3
chr1_+_181033887 Show fit	0.08	ENST00000684662.1 ENST00000434571.7 ENST00000367580.6 ENST00000617803.5 ENST00000683652.1 ENST00000367579.7 ENST00000282990.10	MR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class I-related
chr10_+_80356754 Show fit	0.08	ENST00000616870.4 ENST00000411538.5 ENST00000256039.3	DYDC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DPY30 domain containing 2
chr3_+_66220984 Show fit	0.08	ENST00000354883.11 ENST00000336733.10	SLC25A26 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 25 member 26
chr11_-_72722302 Show fit	0.07	ENST00000334211.12	ARAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_+_45847406 Show fit	0.06	ENST00000443527.6 ENST00000616623.4 ENST00000616080.2	CRY2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cryptochrome circadian regulator 2
chr8_-_74321532 Show fit	0.06	ENST00000342232.5	JPH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	junctophilin 1
chr10_-_25062279 Show fit	0.06	ENST00000615958.4	ENKUR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	enkurin, TRPC channel interacting protein
chr4_-_99290975 Show fit	0.05	ENST00000209668.3	ADH1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	alcohol dehydrogenase 1A (class I), alpha polypeptide
chr11_-_6619353 Show fit	0.05	ENST00000642892.1 ENST00000645620.1 ENST00000533371.6 ENST00000647152.1 ENST00000644810.1 ENST00000299427.12 ENST00000682424.1 ENST00000644218.1 ENST00000528657.2 ENST00000531754.2	TPP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tripeptidyl peptidase 1
chr11_+_85628573 Show fit	0.05	ENST00000393375.5 ENST00000358867.11 ENST00000534341.1 ENST00000531274.1	TMEM126B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 126B
chr17_-_19362542 Show fit	0.05	ENST00000440841.1 ENST00000671102.1 ENST00000461069.6	B9D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	B9 domain containing 1
chr9_+_133061981 Show fit	0.05	ENST00000372080.8	CEL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	carboxyl ester lipase
chr19_-_50511203 Show fit	0.05	ENST00000595669.5	JOSD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Josephin domain containing 2
chr17_-_19362669 Show fit	0.04	ENST00000268841.10 ENST00000663089.1 ENST00000675510.1 ENST00000647252.1 ENST00000477683.5 ENST00000575478.7 ENST00000261499.10	B9D1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	B9 domain containing 1
chr8_-_132321509 Show fit	0.04	ENST00000638588.1	KCNQ3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium voltage-gated channel subfamily Q member 3
chr6_+_26383090 Show fit	0.04	ENST00000469230.5 ENST00000490025.5 ENST00000352867.6 ENST00000356709.9 ENST00000493275.5 ENST00000472507.5 ENST00000482536.5 ENST00000432533.6 ENST00000482842.1	BTN2A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin subfamily 2 member A2
chr6_-_32816910 Show fit	0.04	ENST00000447394.1 ENST00000438763.7	HLA-DOB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class II, DO beta
chr1_-_27012837 Show fit	0.04	ENST00000289166.6	TENT5B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	terminal nucleotidyltransferase 5B
chr11_-_118565992 Show fit	0.04	ENST00000264020.6	IFT46 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intraflagellar transport 46
chr6_-_32666648 Show fit	0.03	ENST00000399082.7 ENST00000399079.7 ENST00000374943.8 ENST00000434651.6	HLA-DQB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class II, DQ beta 1
chr1_+_248838211 Show fit	0.03	ENST00000306562.8	ZNF672 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 672
chr1_+_150282526 Show fit	0.03	ENST00000447007.5 ENST00000369095.5 ENST00000369094.5 ENST00000290363.6	CIART Links Ensembl NCBI GeneCards UniProt NextProt Show fit	circadian associated repressor of transcription
chr8_-_98294339 Show fit	0.03	ENST00000341166.3	NIPAL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NIPA like domain containing 2
chr16_+_67347358 Show fit	0.03	ENST00000563189.5	LRRC36 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 36
chr11_-_85719045 Show fit	0.03	ENST00000533057.6 ENST00000533892.5	SYTL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptotagmin like 2
chr11_-_118565810 Show fit	0.03	ENST00000672656.2 ENST00000530872.5 ENST00000264021.8	IFT46 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	intraflagellar transport 46
chr8_-_98294195 Show fit	0.03	ENST00000430223.7	NIPAL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NIPA like domain containing 2
chr19_-_50511146 Show fit	0.03	ENST00000594350.1 ENST00000601423.5	JOSD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Josephin domain containing 2
chr4_-_121952014 Show fit	0.03	ENST00000379645.8	TRPC3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transient receptor potential cation channel subfamily C member 3
chr11_+_7987314 Show fit	0.03	ENST00000531572.2 ENST00000651655.1	EIF3F Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3 subunit F
chr19_-_50511173 Show fit	0.02	ENST00000598418.6	JOSD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Josephin domain containing 2
chr9_-_34895722 Show fit	0.02	ENST00000603640.6 ENST00000603592.1 ENST00000340783.11	FAM205C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 205 member C
chr8_-_97277890 Show fit	0.02	ENST00000322128.5	TSPYL5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TSPY like 5
chr6_-_31357171 Show fit	0.02	ENST00000412585.7 ENST00000434333.1	HLA-B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class I, B
chr13_-_29850605 Show fit	0.02	ENST00000380680.5	UBL3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquitin like 3
chr16_+_67347391 Show fit	0.02	ENST00000435835.3	LRRC36 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	leucine rich repeat containing 36
chr2_+_241149547 Show fit	0.02	ENST00000438799.5 ENST00000402734.5 ENST00000423280.5	PPP1R7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 1 regulatory subunit 7
chr20_+_325536 Show fit	0.02	ENST00000342665.5	SOX12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SRY-box transcription factor 12
chr5_-_56116946 Show fit	0.02	ENST00000434982.2	ANKRD55 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat domain 55
chr6_-_24666854 Show fit	0.02	ENST00000378198.9	TDP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosyl-DNA phosphodiesterase 2
chr10_-_80356710 Show fit	0.02	ENST00000454362.5 ENST00000372204.7 ENST00000372202.6 ENST00000453477.1	DYDC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DPY30 domain containing 1
chr6_+_30489501 Show fit	0.02	ENST00000376630.5	HLA-E Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class I, E
chr6_-_24666591 Show fit	0.01	ENST00000341060.3	TDP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tyrosyl-DNA phosphodiesterase 2
chr19_+_49766962 Show fit	0.01	ENST00000354293.10 ENST00000359032.9	AP2A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adaptor related protein complex 2 subunit alpha 1
chr5_+_120464236 Show fit	0.01	ENST00000407149.7 ENST00000379551.2	PRR16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proline rich 16
chr9_+_130172343 Show fit	0.01	ENST00000372398.6	NCS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuronal calcium sensor 1
chr1_+_45583846 Show fit	0.01	ENST00000437901.6 ENST00000537798.5 ENST00000350030.8 ENST00000527470.5 ENST00000525515.5 ENST00000528238.5 ENST00000470768.5 ENST00000372052.8 ENST00000629893.1 ENST00000351223.7	NASP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear autoantigenic sperm protein
chr1_-_79006680 Show fit	0.01	ENST00000370742.4 ENST00000656841.1	ADGRL4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adhesion G protein-coupled receptor L4
chr6_+_26383176 Show fit	0.01	ENST00000416795.6 ENST00000494184.1	BTN2A2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin subfamily 2 member A2
chr1_-_79006773 Show fit	0.01	ENST00000671209.1	ADGRL4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adhesion G protein-coupled receptor L4
chr12_-_52652207 Show fit	0.01	ENST00000309680.4	KRT2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 2
chr19_-_48615050 Show fit	0.01	ENST00000263266.4	FAM83E Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 83 member E
chr6_-_132757883 Show fit	0.01	ENST00000525289.5 ENST00000326499.11	VNN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	vanin 2
chr6_-_32953017 Show fit	0.00	ENST00000395305.7 ENST00000374843.9 ENST00000395303.7 ENST00000429234.1	HLA-DMA Links Ensembl NCBI GeneCards UniProt NextProt Show fit ENSG00000248993.1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class II, DM alpha novel protein
chr6_-_32763522 Show fit	0.00	ENST00000435145.6 ENST00000437316.7	HLA-DQB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class II, DQ beta 2
chr16_-_57971121 Show fit	0.00	ENST00000251102.13	CNGB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cyclic nucleotide gated channel subunit beta 1
chr3_-_27369355 Show fit	0.00	ENST00000429845.6 ENST00000341435.9 ENST00000435750.1	NEK10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NIMA related kinase 10
chrX_-_40735476 Show fit	0.00	ENST00000324817.6	MED14 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mediator complex subunit 14

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0010900	negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0	0.1	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.0	0.6	GO:0072643	interferon-gamma secretion(GO:0072643)
0.0	0.1	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.0	0.0	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0002399	MHC class II protein complex assembly(GO:0002399)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.6	GO:0042627	chylomicron(GO:0042627)
0.0	0.4	GO:0042613	MHC class II protein complex(GO:0042613)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.7	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.4	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse