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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for RREB1

Z-value: 0.51

Motif logo

Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
ENSG00000124782.20 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RREB1hg38_v1_chr6_+_7107941_71080310.658.4e-02Click!

Activity profile of RREB1 motif

Sorted Z-values of RREB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_35118456 0.79 ENST00000604621.5
FXYD domain containing ion transport regulator 3
chr20_+_59604527 0.78 ENST00000371015.6
phosphatase and actin regulator 3
chr19_-_50953063 0.77 ENST00000391809.6
kallikrein related peptidase 5
chr19_-_50953093 0.77 ENST00000593428.5
kallikrein related peptidase 5
chr19_-_50952942 0.73 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr16_+_68737284 0.61 ENST00000261769.10
ENST00000422392.6
cadherin 1
chr6_-_136526472 0.59 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr19_-_6720641 0.59 ENST00000245907.11
complement C3
chr6_-_136526654 0.55 ENST00000611373.1
microtubule associated protein 7
chr17_-_41521719 0.54 ENST00000393976.6
keratin 15
chr8_-_74321532 0.46 ENST00000342232.5
junctophilin 1
chr8_+_32548303 0.44 ENST00000650967.1
neuregulin 1
chr14_-_105168753 0.40 ENST00000331782.8
ENST00000347004.2
jagged canonical Notch ligand 2
chr8_+_32548210 0.39 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr11_+_1099730 0.35 ENST00000674892.1
mucin 2, oligomeric mucus/gel-forming
chrX_+_103330206 0.35 ENST00000372666.1
ENST00000332431.5
transcription elongation factor A like 7
chr2_+_222424520 0.34 ENST00000321276.8
sphingosine-1-phosphate phosphatase 2
chr18_+_36297661 0.30 ENST00000257209.8
ENST00000590592.5
ENST00000359247.8
formin homology 2 domain containing 3
chr4_-_86453278 0.29 ENST00000638867.2
ENST00000642019.1
ENST00000641313.1
mitogen-activated protein kinase 10
chr2_+_105851748 0.28 ENST00000425756.1
ENST00000393349.2
NCK adaptor protein 2
chr2_-_46542555 0.25 ENST00000522587.6
ATPase H+ transporting V1 subunit E2
chr2_+_233195433 0.24 ENST00000417661.1
inositol polyphosphate-5-phosphatase D
chr1_+_212608628 0.24 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
activating transcription factor 3
chr12_-_12562851 0.22 ENST00000298573.9
dual specificity phosphatase 16
chr4_-_86453075 0.22 ENST00000641384.1
ENST00000642009.1
ENST00000641274.1
ENST00000641629.1
ENST00000641718.1
ENST00000641782.1
ENST00000511328.5
ENST00000503911.5
ENST00000641862.1
ENST00000640445.1
ENST00000641675.1
ENST00000361569.8
ENST00000639989.2
ENST00000641120.1
ENST00000642023.1
ENST00000641902.1
ENST00000641016.1
ENST00000509464.7
ENST00000638946.2
ENST00000395160.9
ENST00000512017.7
ENST00000639972.2
mitogen-activated protein kinase 10
chr1_+_101238090 0.21 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr12_-_12562344 0.20 ENST00000228862.3
dual specificity phosphatase 16
chr8_+_32548267 0.19 ENST00000356819.7
neuregulin 1
chr4_-_86453370 0.19 ENST00000641297.1
ENST00000641952.1
ENST00000641657.1
ENST00000642048.1
ENST00000641170.1
mitogen-activated protein kinase 10
chr19_+_5805018 0.17 ENST00000303212.3
neurturin
chr6_-_13486137 0.17 ENST00000612338.4
glucose-fructose oxidoreductase domain containing 1
chr22_+_32354885 0.16 ENST00000397468.5
ret finger protein like 3
chr12_+_26195313 0.16 ENST00000422622.3
sarcospan
chr12_+_54053815 0.15 ENST00000430889.3
homeobox C4
chr1_-_32901330 0.15 ENST00000329151.5
ENST00000373463.8
transmembrane protein 54
chr12_-_57129001 0.15 ENST00000556155.5
signal transducer and activator of transcription 6
chr16_+_27313879 0.14 ENST00000562142.5
ENST00000561742.5
ENST00000543915.6
ENST00000395762.7
ENST00000563002.5
interleukin 4 receptor
chr19_+_48364361 0.14 ENST00000344846.7
synaptogyrin 4
chr1_-_47997348 0.14 ENST00000606738.3
TraB domain containing 2B
chr12_+_26195543 0.14 ENST00000242729.7
sarcospan
chr19_-_43802438 0.14 ENST00000377950.8
LY6/PLAUR domain containing 5
chr11_+_128693887 0.13 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr17_+_37489882 0.13 ENST00000617516.5
dual specificity phosphatase 14
chr6_+_112054075 0.13 ENST00000230529.9
ENST00000604763.5
ENST00000368666.7
ENST00000674325.1
ENST00000483439.1
ENST00000409166.5
cellular communication network factor 6
chr4_-_99563984 0.13 ENST00000394877.7
tRNA methyltransferase 10A
chr4_-_99564026 0.13 ENST00000394876.7
tRNA methyltransferase 10A
chr12_-_94650506 0.13 ENST00000261226.9
transmembrane and coiled-coil domain family 3
chrX_+_152733751 0.12 ENST00000393869.8
ENST00000357916.8
MAGE family member A12
chrX_+_151912878 0.12 ENST00000276344.6
MAGE family member A4
chr12_+_131929219 0.12 ENST00000322060.9
pseudouridine synthase 1
chr4_-_99563668 0.12 ENST00000273962.7
tRNA methyltransferase 10A
chr1_-_155978144 0.12 ENST00000313695.11
ENST00000497907.5
Rho/Rac guanine nucleotide exchange factor 2
chr19_+_6135635 0.12 ENST00000588304.5
ENST00000588722.5
ENST00000588485.6
ENST00000591403.5
ENST00000586696.5
ENST00000681525.1
ENST00000589401.5
acyl-CoA synthetase bubblegum family member 2
chr9_-_81689536 0.12 ENST00000376499.8
TLE family member 1, transcriptional corepressor
chr12_+_131929259 0.11 ENST00000542167.2
ENST00000376649.8
ENST00000538037.5
ENST00000456665.6
pseudouridine synthase 1
chr12_+_131929194 0.11 ENST00000443358.6
pseudouridine synthase 1
chr8_+_144477975 0.11 ENST00000435887.2
protein phosphatase 1 regulatory subunit 16A
chr3_-_195909711 0.11 ENST00000333602.14
tyrosine kinase non receptor 2
chr11_-_75351686 0.11 ENST00000360025.7
arrestin beta 1
chr8_+_32548590 0.11 ENST00000652588.1
ENST00000521670.5
ENST00000287842.7
neuregulin 1
chr10_+_125973373 0.11 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
fibronectin type III and ankyrin repeat domains 1
chr3_+_57060658 0.11 ENST00000334325.2
spermatogenesis associated 12
chr7_-_712437 0.11 ENST00000360274.8
protein kinase cAMP-dependent type I regulatory subunit beta
chr8_+_32548661 0.11 ENST00000650980.1
ENST00000405005.7
neuregulin 1
chr19_-_38735405 0.11 ENST00000597987.5
ENST00000595177.1
calpain 12
chr16_+_50693568 0.10 ENST00000647318.2
ENST00000531674.1
nucleotide binding oligomerization domain containing 2
chrX_+_151912458 0.10 ENST00000431963.6
ENST00000682265.1
MAGE family member A4
chr17_-_45425620 0.10 ENST00000376922.6
Rho GTPase activating protein 27
chr7_-_24757413 0.09 ENST00000645220.1
ENST00000409970.6
gasdermin E
chr2_-_32011001 0.09 ENST00000404530.6
mediator of cell motility 1
chr3_-_116444983 0.09 ENST00000333617.8
limbic system associated membrane protein
chr19_-_42255119 0.09 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr19_+_43581037 0.09 ENST00000562365.2
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr5_+_79612410 0.09 ENST00000423041.6
ENST00000504233.5
ENST00000453514.6
ENST00000428308.6
terminal nucleotidyltransferase 2
chrX_-_120115909 0.09 ENST00000217999.3
Rhox homeobox family member 1
chr5_+_79612560 0.09 ENST00000296783.7
terminal nucleotidyltransferase 2
chr17_+_7015035 0.09 ENST00000552775.1
chromosome 17 open reading frame 49
chr19_+_2163915 0.09 ENST00000398665.8
DOT1 like histone lysine methyltransferase
chrX_+_37685773 0.09 ENST00000378616.5
X-linked Kx blood group
chr17_+_7884783 0.08 ENST00000380358.9
chromodomain helicase DNA binding protein 3
chr4_+_8229170 0.08 ENST00000511002.6
SH3 domain and tetratricopeptide repeats 1
chr15_+_77420668 0.08 ENST00000381714.7
ENST00000558651.5
high mobility group 20A
chr9_-_114682172 0.08 ENST00000436752.3
testis expressed 48
chrX_+_150568595 0.08 ENST00000370396.7
ENST00000424519.1
myotubularin 1
chr19_-_40714641 0.08 ENST00000678467.1
coenzyme Q8B
chr20_-_38165261 0.08 ENST00000361475.7
transglutaminase 2
chr17_-_6556447 0.08 ENST00000421306.7
PITPNM family member 3
chr11_+_67119245 0.08 ENST00000529006.7
ENST00000398645.6
lysine demethylase 2A
chr19_-_18941117 0.08 ENST00000600077.5
homer scaffold protein 3
chr5_-_142686079 0.08 ENST00000337706.7
fibroblast growth factor 1
chr11_-_57322197 0.08 ENST00000532437.1
tankyrase 1 binding protein 1
chr17_-_6556539 0.07 ENST00000262483.13
PITPNM family member 3
chr5_+_175872741 0.07 ENST00000502265.5
complexin 2
chr19_-_33064872 0.07 ENST00000254260.8
rhophilin Rho GTPase binding protein 2
chr7_-_128405930 0.07 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
inosine monophosphate dehydrogenase 1
chr19_+_40799425 0.07 ENST00000593972.1
egl-9 family hypoxia inducible factor 2
chr12_-_7936177 0.07 ENST00000544291.1
ENST00000075120.12
solute carrier family 2 member 3
chrX_+_152698767 0.07 ENST00000417212.5
ENST00000598245.2
ENST00000370278.4
MAGE family member A3
chr5_-_142685654 0.07 ENST00000378046.5
ENST00000619447.4
fibroblast growth factor 1
chr12_+_54549586 0.07 ENST00000243052.8
phosphodiesterase 1B
chr19_+_40799796 0.07 ENST00000596517.1
egl-9 family hypoxia inducible factor 2
chrX_-_152769677 0.07 ENST00000457643.1
ENST00000616035.4
ENST00000412733.1
ENST00000329342.9
MAGE family member A6
chr19_+_40799707 0.07 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
ENST00000593525.1
egl-9 family hypoxia inducible factor 2
chr1_-_228416841 0.07 ENST00000366698.7
ENST00000457345.2
tripartite motif containing 17
chr12_-_123272234 0.07 ENST00000544658.5
cyclin dependent kinase 2 associated protein 1
chr1_-_94121105 0.07 ENST00000649773.1
ENST00000370225.4
ATP binding cassette subfamily A member 4
chr8_-_143541425 0.06 ENST00000262577.6
zinc finger CCCH-type containing 3
chr19_+_43580544 0.06 ENST00000562255.5
ENST00000569031.6
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chrX_+_120362079 0.06 ENST00000539306.5
ENST00000218008.8
ENST00000361319.3
ATPase Na+/K+ transporting family member beta 4
chr12_-_123364781 0.06 ENST00000267176.8
ENST00000602398.3
strawberry notch homolog 1
chr5_+_151212117 0.06 ENST00000523466.5
GM2 ganglioside activator
chr15_-_89221558 0.06 ENST00000268125.10
retinaldehyde binding protein 1
chr1_-_173917281 0.06 ENST00000367698.4
serpin family C member 1
chr3_+_8733779 0.06 ENST00000343849.3
ENST00000397368.2
caveolin 3
chr3_+_41200104 0.06 ENST00000643297.1
ENST00000450969.6
catenin beta 1
chr12_+_26195647 0.06 ENST00000535504.1
sarcospan
chr10_-_110304894 0.06 ENST00000369603.10
survival motor neuron domain containing 1
chr17_-_75844334 0.06 ENST00000592386.5
ENST00000412096.6
ENST00000586147.1
ENST00000207549.9
unc-13 homolog D
chr6_+_31946086 0.06 ENST00000425368.7
complement factor B
chr12_-_16606795 0.06 ENST00000447609.5
LIM domain only 3
chr11_+_2301987 0.06 ENST00000612299.4
ENST00000182290.9
tetraspanin 32
chr9_+_129665603 0.06 ENST00000372469.6
paired related homeobox 2
chr20_-_45101112 0.06 ENST00000306117.5
ENST00000537075.3
potassium voltage-gated channel modifier subfamily S member 1
chr18_-_3874270 0.06 ENST00000400149.7
ENST00000400155.5
ENST00000400150.7
DLG associated protein 1
chr14_+_103121457 0.06 ENST00000333007.8
TNF alpha induced protein 2
chr13_-_46386504 0.06 ENST00000417405.2
rubicon like autophagy enhancer
chr19_-_18941184 0.06 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr1_-_156282799 0.06 ENST00000361813.5
SMG5 nonsense mediated mRNA decay factor
chr8_+_141416078 0.05 ENST00000349124.3
protein tyrosine phosphatase 4A3
chr6_-_35512863 0.05 ENST00000428978.1
ENST00000614066.4
ENST00000322263.8
TUB like protein 1
chr2_-_136116165 0.05 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr1_+_23778377 0.05 ENST00000246151.9
PITH domain containing 1
chr22_-_32205001 0.05 ENST00000652607.1
ret finger protein like 2
chr15_+_77420880 0.05 ENST00000336216.9
ENST00000558176.1
high mobility group 20A
chr12_-_121793668 0.05 ENST00000267205.7
ras homolog family member F, filopodia associated
chr18_-_3874247 0.05 ENST00000581699.5
DLG associated protein 1
chr6_+_7107941 0.05 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
ras responsive element binding protein 1
chr3_+_41200080 0.05 ENST00000644524.1
catenin beta 1
chr16_-_4538761 0.05 ENST00000567695.6
ENST00000562334.5
ENST00000562579.5
ENST00000563507.5
cell death inducing p53 target 1
chr8_+_141416141 0.05 ENST00000680615.1
protein tyrosine phosphatase 4A3
chr3_+_41199494 0.05 ENST00000644138.1
ENST00000645276.1
ENST00000642426.1
ENST00000349496.11
ENST00000646116.1
ENST00000644873.1
ENST00000644867.1
ENST00000646725.1
ENST00000645493.1
ENST00000646369.1
ENST00000647413.1
ENST00000643977.1
catenin beta 1
chr9_+_93263948 0.05 ENST00000448251.5
WNK lysine deficient protein kinase 2
chr20_+_836052 0.04 ENST00000246100.3
family with sequence similarity 110 member A
chr7_-_51316754 0.04 ENST00000632460.1
ENST00000441453.5
ENST00000648294.1
ENST00000265136.12
ENST00000395542.6
ENST00000395540.6
cordon-bleu WH2 repeat protein
chr22_-_37580075 0.04 ENST00000215886.6
galectin 2
chr2_+_85616129 0.04 ENST00000409025.5
ENST00000409470.5
ENST00000323701.11
ENST00000409766.7
ubiquitin specific peptidase 39
chr3_+_41199462 0.04 ENST00000647264.1
ENST00000645900.1
ENST00000646174.1
ENST00000643992.1
ENST00000647390.1
ENST00000642886.1
catenin beta 1
chr21_+_42653585 0.04 ENST00000291539.11
phosphodiesterase 9A
chr7_+_98211431 0.04 ENST00000609256.2
basic helix-loop-helix family member a15
chr2_+_227472363 0.04 ENST00000409315.5
ENST00000373671.7
ENST00000409171.5
ArfGAP with FG repeats 1
chr19_+_40799155 0.04 ENST00000303961.9
egl-9 family hypoxia inducible factor 2
chr3_+_37861926 0.04 ENST00000443503.6
CTD small phosphatase like
chr17_+_2055094 0.04 ENST00000399849.4
ENST00000619757.5
HIC ZBTB transcriptional repressor 1
chr1_+_220094086 0.04 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chr20_+_43667019 0.04 ENST00000396863.8
MYB proto-oncogene like 2
chr19_-_56840661 0.04 ENST00000649735.1
ENST00000593695.5
ENST00000599577.5
ENST00000594389.1
ENST00000648694.1
ENST00000326441.15
ENST00000649680.1
ENST00000649876.1
ENST00000650632.1
ENST00000650102.1
ENST00000647621.1
ENST00000598410.5
ENST00000649233.1
ENST00000593711.6
ENST00000629319.2
ENST00000599935.5
paternally expressed 3
zinc finger imprinted 2
chr6_-_31592952 0.04 ENST00000376073.8
ENST00000376072.7
natural cytotoxicity triggering receptor 3
chr19_+_35666515 0.04 ENST00000617999.4
ENST00000616789.4
uroplakin 1A
chr20_+_43667105 0.04 ENST00000217026.5
MYB proto-oncogene like 2
chr18_-_3874751 0.04 ENST00000515196.6
ENST00000534970.5
DLG associated protein 1
chr17_+_60421697 0.04 ENST00000474834.5
chromosome 17 open reading frame 64
chr1_-_204411804 0.04 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr9_+_130172343 0.04 ENST00000372398.6
neuronal calcium sensor 1
chr12_+_56021316 0.04 ENST00000547791.2
IKAROS family zinc finger 4
chr21_+_42653734 0.04 ENST00000335512.8
ENST00000328862.10
ENST00000335440.10
ENST00000380328.6
ENST00000398225.7
ENST00000398227.7
ENST00000398229.7
ENST00000398232.7
ENST00000398234.7
ENST00000398236.7
ENST00000349112.7
ENST00000398224.3
phosphodiesterase 9A
chr15_-_77632869 0.04 ENST00000355300.7
leucine rich repeat and Ig domain containing 1
chr3_-_52835011 0.04 ENST00000446157.3
musculoskeletal, embryonic nuclear protein 1
chr1_-_228416626 0.04 ENST00000355586.4
ENST00000520264.1
ENST00000479800.1
ENST00000295033.7
tripartite motif containing 17
chr18_-_23662810 0.04 ENST00000322980.13
ankyrin repeat domain 29
chr12_+_118016690 0.04 ENST00000537315.5
ENST00000454402.7
ENST00000484086.6
ENST00000420967.5
ENST00000392542.6
ENST00000535092.1
replication factor C subunit 5
chr10_-_101843920 0.04 ENST00000358038.7
potassium voltage-gated channel interacting protein 2
chr6_+_33420201 0.04 ENST00000644458.1
ENST00000449372.7
ENST00000628646.2
ENST00000418600.7
synaptic Ras GTPase activating protein 1
chr19_-_50968125 0.04 ENST00000594641.1
kallikrein related peptidase 6
chr11_-_130002818 0.04 ENST00000358825.9
ENST00000360871.8
ENST00000528746.5
PR/SET domain 10
chrX_-_14873027 0.04 ENST00000452869.1
ENST00000398334.5
ENST00000650831.1
ENST00000324138.7
FA complementation group B
chr4_-_55546900 0.04 ENST00000513440.6
clock circadian regulator
chr4_-_24912886 0.04 ENST00000504487.5
coiled-coil domain containing 149
chr6_-_35512882 0.03 ENST00000229771.11
TUB like protein 1
chr12_+_62260374 0.03 ENST00000312635.10
ENST00000280377.10
ENST00000549237.5
ubiquitin specific peptidase 15
chr17_-_68601357 0.03 ENST00000592554.2
FAM20A golgi associated secretory pathway pseudokinase
chr18_+_74499861 0.03 ENST00000324301.12
carnosine dipeptidase 2
chr19_+_40799501 0.03 ENST00000406058.6
ENST00000593726.5
egl-9 family hypoxia inducible factor 2
chr14_-_70600643 0.03 ENST00000554963.5
ENST00000256379.10
ENST00000430055.6
ENST00000440435.2
ENST00000615788.4
mediator complex subunit 6
chrX_-_48835553 0.03 ENST00000218230.6
proprotein convertase subtilisin/kexin type 1 inhibitor
chr7_+_152759744 0.03 ENST00000377776.7
ENST00000256001.13
ENST00000397282.2
actin related protein 3B
chrX_+_123859976 0.03 ENST00000371199.8
X-linked inhibitor of apoptosis
chr18_-_46559289 0.03 ENST00000419859.1
ENST00000582408.6
ENST00000300591.11
lipoxygenase homology domains 1
chr16_-_31428325 0.03 ENST00000287490.5
cytochrome c oxidase subunit 6A2
chr1_+_84506397 0.03 ENST00000490879.8
spermatogenesis associated 1
chr6_-_31592992 0.03 ENST00000340027.10
natural cytotoxicity triggering receptor 3
chr12_-_120250145 0.03 ENST00000458477.6
paxillin
chr19_+_43576800 0.03 ENST00000612042.4
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr10_+_112374110 0.03 ENST00000354655.9
acyl-CoA synthetase long chain family member 5
chr11_-_59668981 0.03 ENST00000300146.10
PAT1 homolog 1, processing body mRNA decay factor
chr3_+_4814528 0.03 ENST00000478515.2
ENST00000649139.1
ENST00000647685.1
ENST00000649908.1
inositol 1,4,5-trisphosphate receptor type 1
chr19_-_48637338 0.03 ENST00000601104.1
ENST00000222122.10
D-box binding PAR bZIP transcription factor
chr20_+_58689124 0.03 ENST00000525967.5
ENST00000525817.5
aminopeptidase like 1
chrX_-_152138493 0.03 ENST00000583636.5
ENST00000509345.6
ENST00000444834.6
ENST00000579960.1
MAGEA10-MAGEA5 readthrough
MAGE family member A10
chr3_+_193241128 0.03 ENST00000650797.1
phospholipase A and acyltransferase 1
chr12_-_57251169 0.03 ENST00000554578.5
ENST00000546246.2
ENST00000332782.7
ENST00000553489.1
SH3 and cysteine rich domain 3

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.6 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.1 0.3 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 1.2 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.4 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.8 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 0.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.0 0.4 GO:0009912 auditory receptor cell fate commitment(GO:0009912) gamma-delta T cell differentiation(GO:0042492) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0032499 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.3 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.0 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0044691 tooth eruption(GO:0044691)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.4 GO:0070701 mucus layer(GO:0070701)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.8 GO:0016600 flotillin complex(GO:0016600)
0.0 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.2 GO:0030673 axolemma(GO:0030673)
0.0 0.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.1 GO:0032428 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0030305 heparanase activity(GO:0030305)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac