Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
SMAD1 | hg38_v1_chr4_+_145482761_145482820 | 0.62 | 1.0e-01 | Click! |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr19_-_50953093 Show fit | 4.18 |
ENST00000593428.5
|
kallikrein related peptidase 5 |
|
chr2_+_101991953 Show fit | 3.70 |
ENST00000332549.8
|
interleukin 1 receptor type 2 |
|
chr19_-_50952942 Show fit | 3.70 |
ENST00000594846.1
ENST00000336334.8 |
kallikrein related peptidase 5 |
|
chr19_-_50953063 Show fit | 3.06 |
ENST00000391809.6
|
kallikrein related peptidase 5 |
|
chr1_-_153616289 Show fit | 2.44 |
ENST00000368701.5
ENST00000344616.4 |
S100 calcium binding protein A14 |
|
chr4_-_15938740 Show fit | 2.02 |
ENST00000382333.2
|
fibroblast growth factor binding protein 1 |
|
chr19_-_51020019 Show fit | 1.73 |
ENST00000309958.7
|
kallikrein related peptidase 10 |
|
chr19_-_51020154 Show fit | 1.71 |
ENST00000391805.5
ENST00000599077.1 |
kallikrein related peptidase 10 |
|
chr2_+_102008515 Show fit | 1.67 |
ENST00000441002.1
|
interleukin 1 receptor type 2 |
|
chr19_-_35513641 Show fit | 1.60 |
ENST00000339686.8
ENST00000447113.6 |
dermokine |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 11.0 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803) |
0.1 | 8.6 | GO:0070268 | cornification(GO:0070268) |
1.5 | 6.0 | GO:0032690 | negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712) |
0.2 | 4.7 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
0.1 | 4.2 | GO:0006953 | acute-phase response(GO:0006953) |
0.7 | 2.9 | GO:0042361 | menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377) |
0.3 | 2.8 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
0.6 | 2.5 | GO:0032600 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
0.1 | 2.4 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
0.1 | 2.2 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.7 | 11.8 | GO:0097209 | epidermal lamellar body(GO:0097209) |
0.1 | 4.5 | GO:0001533 | cornified envelope(GO:0001533) |
0.2 | 4.1 | GO:0005922 | connexon complex(GO:0005922) |
0.1 | 3.7 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 3.7 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 3.5 | GO:0035578 | azurophil granule lumen(GO:0035578) |
0.2 | 3.2 | GO:0005861 | troponin complex(GO:0005861) |
0.0 | 3.0 | GO:0070821 | tertiary granule membrane(GO:0070821) |
0.7 | 2.9 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
0.1 | 2.7 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 21.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.1 | 7.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
1.2 | 5.9 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
0.0 | 4.6 | GO:0005125 | cytokine activity(GO:0005125) |
0.1 | 4.1 | GO:0042379 | chemokine receptor binding(GO:0042379) |
0.1 | 3.5 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.2 | 3.0 | GO:0031014 | troponin T binding(GO:0031014) |
0.1 | 2.8 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
0.0 | 2.2 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.2 | 2.0 | GO:0038132 | neuregulin binding(GO:0038132) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 12.1 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
0.1 | 8.8 | PID IL1 PATHWAY | IL1-mediated signaling events |
0.1 | 3.9 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
0.0 | 3.9 | PID P73PATHWAY | p73 transcription factor network |
0.0 | 3.3 | PID NOTCH PATHWAY | Notch signaling pathway |
0.1 | 2.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.1 | 2.3 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.0 | 1.8 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 1.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.0 | 1.6 | PID EPO PATHWAY | EPO signaling pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 7.6 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
0.0 | 5.0 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.2 | 4.3 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.1 | 3.6 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
0.0 | 3.2 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
0.0 | 2.9 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
0.0 | 1.8 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 1.8 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
0.1 | 1.6 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
0.1 | 1.5 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |