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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SOX13_SOX12

Z-value: 0.73

Motif logo

Transcription factors associated with SOX13_SOX12

Gene Symbol Gene ID Gene Info
ENSG00000143842.15 SRY-box transcription factor 13
ENSG00000177732.9 SRY-box transcription factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX12hg38_v1_chr20_+_325536_325565-0.393.4e-01Click!
SOX13hg38_v1_chr1_+_204073104_2040731210.206.3e-01Click!

Activity profile of SOX13_SOX12 motif

Sorted Z-values of SOX13_SOX12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_116427839 1.69 ENST00000369230.4
pancreatic lipase related protein 3
chr1_+_153031195 1.32 ENST00000307098.5
small proline rich protein 1B
chr12_-_8662703 0.94 ENST00000535336.5
microfibril associated protein 5
chr12_-_8662619 0.88 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr6_-_136526472 0.82 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr10_-_104085847 0.79 ENST00000648076.2
collagen type XVII alpha 1 chain
chr2_+_206939515 0.72 ENST00000272852.4
carboxypeptidase O
chr2_+_102311502 0.71 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr12_-_8650529 0.69 ENST00000543467.5
microfibril associated protein 5
chr5_+_140841183 0.68 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr11_+_7088991 0.62 ENST00000306904.7
RBMX like 2
chr13_-_85799400 0.60 ENST00000647374.2
SLIT and NTRK like family member 6
chr6_-_136466858 0.60 ENST00000544465.5
microtubule associated protein 7
chr12_-_8662808 0.60 ENST00000359478.7
ENST00000396549.6
microfibril associated protein 5
chr19_+_35118456 0.58 ENST00000604621.5
FXYD domain containing ion transport regulator 3
chr3_-_151316795 0.55 ENST00000260843.5
G protein-coupled receptor 87
chr5_+_140855882 0.55 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
protocadherin alpha 10
chr12_+_50924005 0.53 ENST00000550502.1
methyltransferase like 7A
chr12_-_8662073 0.53 ENST00000535411.5
ENST00000540087.5
microfibril associated protein 5
chr5_+_140834230 0.52 ENST00000356878.5
ENST00000525929.2
protocadherin alpha 7
chr18_+_63587297 0.47 ENST00000269489.9
serpin family B member 13
chr21_+_42199686 0.47 ENST00000398457.6
ATP binding cassette subfamily G member 1
chr5_+_148203024 0.46 ENST00000325630.3
serine peptidase inhibitor Kazal type 6
chr5_+_35856883 0.46 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr2_-_216013517 0.45 ENST00000263268.11
melanoregulin
chr18_+_63587336 0.45 ENST00000344731.10
serpin family B member 13
chr1_+_76867469 0.44 ENST00000477717.6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr1_-_153460644 0.43 ENST00000368723.4
S100 calcium binding protein A7
chr8_+_32721823 0.43 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chr5_-_83673544 0.42 ENST00000503117.1
ENST00000510978.5
hyaluronan and proteoglycan link protein 1
chr5_+_140868945 0.42 ENST00000398640.7
protocadherin alpha 11
chr6_-_11778781 0.41 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr3_+_111998739 0.41 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr2_-_237590660 0.40 ENST00000409576.1
RAB17, member RAS oncogene family
chr8_-_124728273 0.40 ENST00000325064.9
ENST00000518547.6
MTSS I-BAR domain containing 1
chr5_+_36596583 0.39 ENST00000680318.1
solute carrier family 1 member 3
chr11_-_102780620 0.39 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr18_+_49562049 0.38 ENST00000261292.9
ENST00000427224.6
ENST00000580036.5
lipase G, endothelial type
chr5_+_140882116 0.38 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
protocadherin alpha 13
chr12_+_8950036 0.38 ENST00000539240.5
killer cell lectin like receptor G1
chr12_-_27972725 0.37 ENST00000545234.6
parathyroid hormone like hormone
chr5_+_148202771 0.36 ENST00000514389.5
ENST00000621437.4
serine peptidase inhibitor Kazal type 6
chr6_-_136526654 0.36 ENST00000611373.1
microtubule associated protein 7
chr4_+_52862308 0.35 ENST00000248706.5
RAS like family 11 member B
chr18_+_63775369 0.33 ENST00000540675.5
serpin family B member 7
chr2_+_131011683 0.33 ENST00000355771.7
Rho guanine nucleotide exchange factor 4
chr11_-_60183011 0.32 ENST00000533023.5
ENST00000420732.6
ENST00000528851.6
membrane spanning 4-domains A6A
chr18_+_58341038 0.32 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr5_+_140875299 0.32 ENST00000613593.1
ENST00000398631.3
protocadherin alpha 12
chr10_-_5003850 0.31 ENST00000421196.7
ENST00000455190.2
ENST00000380753.8
aldo-keto reductase family 1 member C2
chr16_+_2817230 0.31 ENST00000005995.8
ENST00000574813.5
serine protease 21
chr11_+_128694052 0.31 ENST00000527786.7
ENST00000534087.3
Fli-1 proto-oncogene, ETS transcription factor
chr9_-_137302264 0.31 ENST00000356628.4
NOTCH regulated ankyrin repeat protein
chr7_-_105522264 0.31 ENST00000469408.6
pseudouridine synthase 7
chr11_+_128693887 0.30 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_53510445 0.30 ENST00000509541.5
glutamate-cysteine ligase catalytic subunit
chr2_-_237590694 0.30 ENST00000264601.8
ENST00000411462.5
ENST00000409822.1
RAB17, member RAS oncogene family
chr1_+_161707244 0.30 ENST00000349527.8
ENST00000294796.8
ENST00000309691.10
ENST00000367953.7
ENST00000367950.2
Fc receptor like A
chr2_-_70553440 0.29 ENST00000450929.5
transforming growth factor alpha
chr6_+_125219804 0.29 ENST00000524679.1
TPD52 like 1
chr3_-_139539577 0.28 ENST00000619087.4
retinol binding protein 1
chr2_-_216013582 0.28 ENST00000620139.4
melanoregulin
chr6_+_130421086 0.28 ENST00000545622.5
transmembrane protein 200A
chr15_-_78937198 0.27 ENST00000677207.1
cathepsin H
chr8_-_42501224 0.27 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr4_-_22443110 0.26 ENST00000508133.5
adhesion G protein-coupled receptor A3
chr4_+_99816797 0.26 ENST00000512369.2
ENST00000296414.11
dual adaptor of phosphotyrosine and 3-phosphoinositides 1
chr7_-_105522204 0.26 ENST00000356362.6
pseudouridine synthase 7
chr10_-_121598412 0.25 ENST00000360144.7
ENST00000358487.10
ENST00000369059.5
ENST00000613048.4
ENST00000356226.8
fibroblast growth factor receptor 2
chr12_+_77830886 0.25 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chrX_+_108044967 0.25 ENST00000415430.7
V-set and immunoglobulin domain containing 1
chr2_+_102311546 0.24 ENST00000233954.6
ENST00000447231.5
interleukin 1 receptor like 1
chr11_+_55262152 0.24 ENST00000417545.5
tripartite motif containing 48
chr3_-_112845950 0.24 ENST00000398214.5
CD200 receptor 1 like
chr7_-_41703062 0.24 ENST00000242208.5
inhibin subunit beta A
chr4_+_76435216 0.23 ENST00000296043.7
shroom family member 3
chr10_-_114684612 0.23 ENST00000533213.6
ENST00000369252.8
actin binding LIM protein 1
chr15_-_99251207 0.23 ENST00000394129.6
ENST00000558663.5
ENST00000394135.7
ENST00000561365.5
ENST00000560279.5
tetratricopeptide repeat domain 23
chr7_+_117020191 0.23 ENST00000434836.5
ENST00000393443.5
ENST00000465133.5
ENST00000477742.5
ENST00000393444.7
ENST00000393447.8
suppression of tumorigenicity 7
chr5_+_122129533 0.22 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr14_+_22271921 0.22 ENST00000390464.2
T cell receptor alpha variable 38-1
chr12_+_25052512 0.22 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
inositol 1,4,5-triphosphate receptor associated 2
chr9_-_39239174 0.22 ENST00000358144.6
contactin associated protein family member 3
chr3_+_58008350 0.22 ENST00000490882.5
ENST00000358537.7
ENST00000429972.6
ENST00000682871.1
ENST00000295956.9
filamin B
chr2_-_88947820 0.22 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr13_+_31739520 0.22 ENST00000298386.7
relaxin family peptide receptor 2
chr1_+_161706949 0.21 ENST00000350710.3
ENST00000367949.6
ENST00000367959.6
ENST00000540521.5
ENST00000546024.5
ENST00000674251.1
ENST00000674323.1
Fc receptor like A
chr1_-_153041111 0.21 ENST00000360379.4
small proline rich protein 2D
chr12_-_84892120 0.21 ENST00000680379.1
solute carrier family 6 member 15
chr6_+_106086316 0.21 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr4_-_121381007 0.21 ENST00000394427.3
pyroglutamylated RFamide peptide receptor
chr1_+_161707205 0.21 ENST00000367957.7
Fc receptor like A
chr3_+_32391694 0.20 ENST00000349718.8
CKLF like MARVEL transmembrane domain containing 7
chr1_+_161707222 0.20 ENST00000236938.12
Fc receptor like A
chr13_+_31739542 0.20 ENST00000380314.2
relaxin family peptide receptor 2
chr12_-_54384687 0.20 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
zinc finger protein 385A
chr11_+_34632464 0.20 ENST00000531794.5
ETS homologous factor
chr13_+_73054969 0.20 ENST00000539231.5
Kruppel like factor 5
chr9_-_21385395 0.20 ENST00000380206.4
interferon alpha 2
chr4_+_99511008 0.20 ENST00000514652.5
ENST00000326581.9
chromosome 4 open reading frame 17
chr19_-_55140922 0.20 ENST00000589745.5
troponin T1, slow skeletal type
chr10_-_14604389 0.19 ENST00000468747.5
ENST00000378467.8
family with sequence similarity 107 member B
chr20_-_51768327 0.19 ENST00000311637.9
ENST00000338821.6
ATPase phospholipid transporting 9A (putative)
chr11_+_35180342 0.19 ENST00000639002.1
CD44 molecule (Indian blood group)
chrX_+_106693838 0.19 ENST00000324342.7
ring finger protein 128
chr3_+_32391841 0.19 ENST00000334983.10
CKLF like MARVEL transmembrane domain containing 7
chrX_+_108045050 0.19 ENST00000458383.1
ENST00000217957.10
V-set and immunoglobulin domain containing 1
chr6_+_130018565 0.19 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL histone methyl-lysine binding protein 3
chr1_-_153057504 0.18 ENST00000392653.3
small proline rich protein 2A
chr3_+_32391871 0.18 ENST00000465248.1
CKLF like MARVEL transmembrane domain containing 7
chr17_+_58238426 0.18 ENST00000421678.6
ENST00000262290.9
ENST00000543544.5
lactoperoxidase
chr14_+_39233908 0.18 ENST00000280082.4
MIA SH3 domain ER export factor 2
chr11_+_35176575 0.18 ENST00000526000.6
CD44 molecule (Indian blood group)
chr6_+_116399395 0.18 ENST00000644499.1
novel protein
chr12_+_25052634 0.18 ENST00000548766.5
inositol 1,4,5-triphosphate receptor associated 2
chr4_+_186227501 0.18 ENST00000446598.6
ENST00000264690.11
ENST00000513864.2
kallikrein B1
chr11_-_48983826 0.17 ENST00000649162.1
tripartite motif-containing 51G, pseudogene
chr6_+_137867414 0.17 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr2_+_90114838 0.17 ENST00000417279.3
immunoglobulin kappa variable 3D-15
chr19_-_42594918 0.17 ENST00000244336.10
CEA cell adhesion molecule 8
chr5_+_40841308 0.17 ENST00000381677.4
ENST00000254691.10
caspase recruitment domain family member 6
chr4_-_142305935 0.17 ENST00000511838.5
inositol polyphosphate-4-phosphatase type II B
chr4_-_142305826 0.17 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr5_-_177409535 0.17 ENST00000253496.4
coagulation factor XII
chr6_+_12290353 0.17 ENST00000379375.6
endothelin 1
chrX_-_32155462 0.17 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr6_-_139291987 0.17 ENST00000358430.8
taxilin beta
chr11_-_89921767 0.17 ENST00000530311.6
tripartite motif containing 49D1
chrX_-_79367307 0.17 ENST00000373298.7
integral membrane protein 2A
chr8_-_85341705 0.17 ENST00000517618.5
carbonic anhydrase 1
chr6_-_53148822 0.17 ENST00000259803.8
glial cells missing transcription factor 1
chr6_-_49744434 0.16 ENST00000433368.6
ENST00000354620.4
cysteine rich secretory protein 3
chrX_-_19965142 0.16 ENST00000340625.3
BCLAF1 and THRAP3 family member 3
chrX_+_23908006 0.16 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chr17_+_55751021 0.16 ENST00000268896.10
ENST00000576183.5
ENST00000573500.5
phosphatidylcholine transfer protein
chr18_+_44680875 0.16 ENST00000649279.2
ENST00000677699.1
SET binding protein 1
chr5_+_141187138 0.15 ENST00000316105.7
ENST00000624909.1
protocadherin beta 9
chr10_-_59753388 0.15 ENST00000430431.5
myoregulin
chr6_-_116060859 0.15 ENST00000606080.2
fyn related Src family tyrosine kinase
chr4_-_89838289 0.15 ENST00000336904.7
synuclein alpha
chr14_+_56117702 0.15 ENST00000559044.5
pellino E3 ubiquitin protein ligase family member 2
chr10_-_107164692 0.15 ENST00000263054.11
sortilin related VPS10 domain containing receptor 1
chr11_+_59713403 0.15 ENST00000641815.1
syntaxin 3
chr1_-_152325232 0.15 ENST00000368799.2
filaggrin
chr19_+_4402615 0.15 ENST00000301280.10
chromatin assembly factor 1 subunit A
chr7_-_36367141 0.15 ENST00000453212.5
ENST00000415803.2
ENST00000431396.1
ENST00000440378.6
ENST00000317020.10
ENST00000436884.5
KIAA0895
chr12_-_31326111 0.14 ENST00000539409.5
SIN3-HDAC complex associated factor
chr21_-_32813679 0.14 ENST00000487113.1
ENST00000382373.4
chromosome 21 open reading frame 62
chr18_-_72544336 0.14 ENST00000269503.9
cerebellin 2 precursor
chr1_+_24319342 0.14 ENST00000361548.9
grainyhead like transcription factor 3
chr16_+_2817180 0.14 ENST00000450020.7
serine protease 21
chr16_+_50266530 0.14 ENST00000566433.6
ENST00000394697.7
ENST00000673801.1
adenylate cyclase 7
chr6_-_118935146 0.14 ENST00000619706.5
ENST00000316316.10
minichromosome maintenance 9 homologous recombination repair factor
chr15_-_75712828 0.14 ENST00000308508.5
chondroitin sulfate proteoglycan 4
chr11_-_60184633 0.14 ENST00000529054.5
ENST00000530839.5
ENST00000426738.6
membrane spanning 4-domains A6A
chr9_-_33473884 0.14 ENST00000297990.9
ENST00000353159.6
ENST00000379471.3
nucleolar protein 6
chr19_+_40775154 0.14 ENST00000594436.5
ENST00000597784.5
MIA SH3 domain containing
chrX_+_105948429 0.14 ENST00000540278.1
Nik related kinase
chrX_+_135309480 0.14 ENST00000635820.1
embryonic testis differentiation homolog C
chr3_-_197226351 0.14 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr1_+_207752046 0.14 ENST00000367042.6
ENST00000322875.8
ENST00000322918.9
ENST00000354848.5
ENST00000357714.5
ENST00000358170.6
ENST00000367041.5
ENST00000367047.5
ENST00000360212.6
ENST00000480003.5
CD46 molecule
chr19_+_15628343 0.14 ENST00000589722.2
cytochrome P450 family 4 subfamily F member 8
chr19_+_1077394 0.14 ENST00000590577.2
Rho GTPase activating protein 45
chr15_-_79090760 0.13 ENST00000419573.7
ENST00000558480.7
Ras protein specific guanine nucleotide releasing factor 1
chr6_+_89433164 0.13 ENST00000369408.9
ENST00000447838.6
ankyrin repeat domain 6
chr10_-_23344678 0.13 ENST00000649478.1
ENST00000636213.3
ENST00000673651.1
ENST00000323327.5
chromosome 10 open reading frame 67
chr19_+_21082140 0.13 ENST00000616183.1
ENST00000596053.5
zinc finger protein 714
chr12_-_31326142 0.13 ENST00000337682.9
SIN3-HDAC complex associated factor
chr14_+_39233884 0.13 ENST00000553728.1
MIA SH3 domain ER export factor 2
chr11_+_55811367 0.13 ENST00000625203.2
olfactory receptor family 5 subfamily L member 1
chr13_-_51974775 0.13 ENST00000674147.1
ATPase copper transporting beta
chr22_-_40862070 0.13 ENST00000307221.5
DnaJ heat shock protein family (Hsp40) member B7
chr1_+_153416517 0.13 ENST00000368729.9
S100 calcium binding protein A7A
chr6_-_49744378 0.13 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr12_-_31326171 0.13 ENST00000542983.1
SIN3-HDAC complex associated factor
chrX_-_33211540 0.13 ENST00000357033.9
dystrophin
chr19_+_41708635 0.13 ENST00000617332.4
ENST00000615021.4
ENST00000616453.1
ENST00000405816.5
ENST00000435837.2
CEA cell adhesion molecule 5
novel protein, readthrough between CEACAM5-CEACAM6
chr17_+_37491464 0.13 ENST00000613659.1
dual specificity phosphatase 14
chr12_+_25052732 0.12 ENST00000547044.5
inositol 1,4,5-triphosphate receptor associated 2
chr17_-_40665121 0.12 ENST00000394052.5
keratin 222
chr12_-_11134644 0.12 ENST00000539585.1
taste 2 receptor member 30
chr14_-_105864247 0.12 ENST00000461719.1
immunoglobulin heavy joining 4
chr9_-_123184233 0.12 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr13_-_46142834 0.12 ENST00000674665.1
lymphocyte cytosolic protein 1
chr8_+_102551583 0.12 ENST00000285402.4
outer dense fiber of sperm tails 1
chr21_-_26051023 0.12 ENST00000415997.1
amyloid beta precursor protein
chr8_+_103819244 0.12 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr6_+_29395631 0.12 ENST00000642051.1
olfactory receptor family 12 subfamily D member 2
chr11_+_73950985 0.12 ENST00000339764.6
DnaJ heat shock protein family (Hsp40) member B13
chr8_+_103880412 0.12 ENST00000436393.6
regulating synaptic membrane exocytosis 2
chr12_+_101594849 0.12 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr6_+_89433127 0.12 ENST00000339746.9
ankyrin repeat domain 6
chr11_+_7605719 0.11 ENST00000530181.5
PPFIA binding protein 2
chr2_+_71453538 0.11 ENST00000258104.8
dysferlin
chr12_-_23951020 0.11 ENST00000441133.2
ENST00000545921.5
SRY-box transcription factor 5
chr16_-_10694922 0.11 ENST00000283025.7
tektin 5
chr12_+_48482492 0.11 ENST00000548364.7
chromosome 12 open reading frame 54
chr4_+_122378966 0.11 ENST00000446706.5
ENST00000296513.7
adenosine deaminase domain containing 1
chr7_+_77538027 0.11 ENST00000433369.6
ENST00000415482.6
protein tyrosine phosphatase non-receptor type 12
chr6_-_112087451 0.11 ENST00000368662.10
tubulin epsilon 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX13_SOX12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.2 0.5 GO:0009720 detection of hormone stimulus(GO:0009720)
0.1 0.6 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 1.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.4 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.3 GO:0051919 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.1 0.4 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.9 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 0.3 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 3.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.2 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.2 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 0.2 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.1 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0060003 copper ion export(GO:0060003)
0.0 0.3 GO:0035603 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.4 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.4 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:1905026 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.4 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.4 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0072757 cellular response to camptothecin(GO:0072757)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.1 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0051563 astrocyte activation involved in immune response(GO:0002265) microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 2.7 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0015820 leucine transport(GO:0015820)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0048549 positive regulation of sodium:proton antiporter activity(GO:0032417) positive regulation of pinocytosis(GO:0048549)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0015827 tryptophan transport(GO:0015827)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 1.7 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.0 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0072387 flavin-containing compound biosynthetic process(GO:0042727) flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.0 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.0 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0032401 establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.1 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.0 0.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 1.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.0 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 2.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 0.3 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.3 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 3.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0008903 hydroxypyruvate isomerase activity(GO:0008903)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.0 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID FGF PATHWAY FGF signaling pathway
0.0 0.8 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME DEVELOPMENTAL BIOLOGY Genes involved in Developmental Biology
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling