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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SOX3_SOX2

Z-value: 1.11

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Transcription factors associated with SOX3_SOX2

Gene Symbol Gene ID Gene Info
ENSG00000134595.9 SRY-box transcription factor 3
ENSG00000181449.4 SRY-box transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX2hg38_v1_chr3_+_181711915_1817119340.821.3e-02Click!
SOX3hg38_v1_chrX_-_140505058_140505076-0.686.2e-02Click!

Activity profile of SOX3_SOX2 motif

Sorted Z-values of SOX3_SOX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_137532452 1.43 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
protocadherin 18
chr4_-_2262082 1.16 ENST00000337190.7
MAX dimerization protein 4
chr18_+_6729698 1.14 ENST00000383472.9
Rho GTPase activating protein 28
chr3_-_18424533 1.11 ENST00000417717.6
SATB homeobox 1
chr9_+_87498491 0.82 ENST00000622514.4
death associated protein kinase 1
chr14_-_59630582 0.79 ENST00000395090.5
reticulon 1
chr8_+_103372388 0.79 ENST00000520337.1
collagen triple helix repeat containing 1
chr1_+_215082731 0.79 ENST00000444842.7
potassium two pore domain channel subfamily K member 2
chr2_+_209579399 0.72 ENST00000360351.8
microtubule associated protein 2
chr14_+_96039328 0.71 ENST00000553764.1
ENST00000555004.3
ENST00000556728.1
ENST00000553782.1
chromosome 14 open reading frame 132
chr20_+_34704336 0.71 ENST00000374809.6
ENST00000374810.8
ENST00000451665.5
tumor protein p53 inducible nuclear protein 2
chr2_+_209579598 0.70 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr9_+_98943898 0.70 ENST00000375001.8
collagen type XV alpha 1 chain
chr15_-_52652031 0.65 ENST00000546305.6
family with sequence similarity 214 member A
chr5_-_111758061 0.63 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
neuronal regeneration related protein
chr18_-_28177102 0.63 ENST00000413878.2
ENST00000269141.8
cadherin 2
chr8_-_119673368 0.61 ENST00000427067.6
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr4_+_26321365 0.56 ENST00000505958.6
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_185956348 0.55 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chrX_+_87517784 0.55 ENST00000373119.9
ENST00000373114.4
kelch like family member 4
chr3_-_114624921 0.54 ENST00000393785.6
zinc finger and BTB domain containing 20
chr3_-_112641128 0.53 ENST00000206423.8
coiled-coil domain containing 80
chr4_-_158159657 0.52 ENST00000590648.5
golgi associated kinase 1B
chr6_+_71886900 0.52 ENST00000517960.5
ENST00000518273.5
ENST00000522291.5
ENST00000521978.5
ENST00000520567.5
ENST00000264839.11
regulating synaptic membrane exocytosis 1
chr4_-_5888400 0.52 ENST00000397890.6
collapsin response mediator protein 1
chr1_-_145707345 0.51 ENST00000417171.6
PDZ domain containing 1
chr9_+_98943705 0.51 ENST00000610452.1
collagen type XV alpha 1 chain
chr1_-_145707387 0.51 ENST00000451928.6
PDZ domain containing 1
chr4_+_26321192 0.50 ENST00000681484.1
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_46132650 0.50 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr2_+_209579429 0.49 ENST00000361559.8
microtubule associated protein 2
chr1_+_89524819 0.49 ENST00000439853.6
ENST00000330947.7
ENST00000449440.5
ENST00000640258.1
leucine rich repeat containing 8 VRAC subunit B
chr1_+_89524871 0.49 ENST00000639264.1
leucine rich repeat containing 8 VRAC subunit B
chr3_-_114624979 0.49 ENST00000676079.1
zinc finger and BTB domain containing 20
chr14_-_59630806 0.48 ENST00000342503.8
reticulon 1
chr4_+_61202142 0.48 ENST00000514591.5
adhesion G protein-coupled receptor L3
chr4_-_185810894 0.48 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chr6_+_113857333 0.48 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr15_-_82045998 0.47 ENST00000329713.5
mex-3 RNA binding family member B
chr15_-_93089192 0.46 ENST00000329082.11
repulsive guidance molecule BMP co-receptor a
chr1_+_33256479 0.46 ENST00000539719.6
ENST00000483388.5
zinc finger protein 362
chr7_+_44748832 0.45 ENST00000309315.9
ENST00000457123.5
zinc finger MIZ-type containing 2
chr15_-_82046119 0.45 ENST00000558133.1
mex-3 RNA binding family member B
chr5_-_151141631 0.45 ENST00000523714.5
ENST00000521749.5
annexin A6
chr12_+_15322529 0.45 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chr5_-_111757704 0.44 ENST00000379671.7
neuronal regeneration related protein
chr1_-_3611470 0.44 ENST00000356575.9
multiple EGF like domains 6
chr6_+_71886703 0.44 ENST00000491071.6
regulating synaptic membrane exocytosis 1
chr5_+_95731300 0.44 ENST00000379982.8
Rho related BTB domain containing 3
chr8_-_38467701 0.43 ENST00000425967.8
ENST00000533668.5
ENST00000413133.6
ENST00000397108.8
ENST00000526742.5
ENST00000525001.5
ENST00000529552.5
ENST00000397113.6
fibroblast growth factor receptor 1
chr9_-_92536031 0.43 ENST00000344604.9
ENST00000375540.5
extracellular matrix protein 2
chr5_-_172283743 0.43 ENST00000393792.3
ubiquitin domain containing 2
chr2_-_144516154 0.43 ENST00000637304.1
zinc finger E-box binding homeobox 2
chr6_-_24877262 0.42 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr1_-_25906457 0.42 ENST00000426559.6
stathmin 1
chr4_+_61200318 0.42 ENST00000683033.1
adhesion G protein-coupled receptor L3
chr5_-_111756245 0.42 ENST00000447165.6
neuronal regeneration related protein
chrX_+_101078861 0.42 ENST00000372930.5
transmembrane protein 35A
chr10_-_68332914 0.42 ENST00000358769.7
ENST00000495025.2
phenazine biosynthesis like protein domain containing
chr10_-_13707536 0.42 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr5_-_39425187 0.41 ENST00000545653.5
DAB adaptor protein 2
chrX_+_81202066 0.41 ENST00000373212.6
SH3 domain binding glutamate rich protein like
chr8_-_38468601 0.41 ENST00000341462.9
ENST00000683765.1
ENST00000356207.9
ENST00000326324.10
ENST00000335922.9
ENST00000532791.5
fibroblast growth factor receptor 1
chrX_-_143635081 0.40 ENST00000338017.8
SLIT and NTRK like family member 4
chr19_+_55647995 0.40 ENST00000593069.1
ENST00000308964.7
coiled-coil domain containing 106
chr17_-_10036741 0.40 ENST00000585266.5
growth arrest specific 7
chr8_-_38468627 0.40 ENST00000683815.1
ENST00000684654.1
ENST00000447712.7
ENST00000397091.9
fibroblast growth factor receptor 1
chr11_-_95232514 0.40 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr9_-_70869076 0.40 ENST00000677594.1
transient receptor potential cation channel subfamily M member 3
chrX_+_55717733 0.40 ENST00000414239.5
ENST00000374941.9
Ras related GTP binding B
chr1_+_244835616 0.39 ENST00000366528.3
ENST00000411948.7
cytochrome c oxidase assembly factor COX20
chr17_+_1771688 0.39 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr19_+_55648198 0.39 ENST00000586790.6
ENST00000588740.5
ENST00000591578.5
coiled-coil domain containing 106
chr11_-_111923722 0.39 ENST00000527950.5
crystallin alpha B
chr4_-_99321362 0.38 ENST00000625860.2
ENST00000305046.13
ENST00000506651.5
alcohol dehydrogenase 1B (class I), beta polypeptide
chr4_-_174522791 0.38 ENST00000541923.5
ENST00000542498.5
15-hydroxyprostaglandin dehydrogenase
chr1_+_159171607 0.38 ENST00000368124.8
ENST00000368125.9
ENST00000416746.1
cell adhesion molecule 3
chr5_-_168883333 0.37 ENST00000404867.7
slit guidance ligand 3
chr9_-_120714457 0.36 ENST00000373930.4
multiple EGF like domains 9
chr8_-_107498041 0.36 ENST00000297450.7
angiopoietin 1
chr5_+_15500172 0.35 ENST00000504595.2
F-box and leucine rich repeat protein 7
chr2_+_32946944 0.35 ENST00000404816.7
latent transforming growth factor beta binding protein 1
chr11_-_111910790 0.35 ENST00000533280.6
crystallin alpha B
chr2_+_209653171 0.35 ENST00000447185.5
microtubule associated protein 2
chr5_+_83471925 0.35 ENST00000502527.2
versican
chr4_-_174522446 0.35 ENST00000296521.11
ENST00000296522.11
ENST00000422112.6
ENST00000504433.1
15-hydroxyprostaglandin dehydrogenase
chr14_-_73027077 0.35 ENST00000553891.5
ENST00000556143.6
zinc finger FYVE-type containing 1
chr14_-_91946989 0.34 ENST00000556154.5
fibulin 5
chr19_+_49361783 0.34 ENST00000594268.1
dickkopf like acrosomal protein 1
chr1_+_164559739 0.34 ENST00000627490.2
PBX homeobox 1
chr11_-_67356970 0.34 ENST00000532830.5
DNA polymerase delta 4, accessory subunit
chr1_+_164559766 0.34 ENST00000367897.5
ENST00000559240.5
PBX homeobox 1
chr8_-_123541197 0.34 ENST00000517956.5
ENST00000443022.2
F-box protein 32
chr9_+_136980211 0.34 ENST00000444903.2
prostaglandin D2 synthase
chr5_+_83471764 0.34 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
versican
chr14_-_73027117 0.34 ENST00000318876.9
zinc finger FYVE-type containing 1
chr11_-_111910888 0.34 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr5_+_172641241 0.34 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr3_+_133400046 0.34 ENST00000302334.3
beaded filament structural protein 2
chr11_-_111910830 0.34 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr16_+_53208438 0.34 ENST00000565442.1
chromodomain helicase DNA binding protein 9
chr5_-_39424966 0.34 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr16_+_68539737 0.34 ENST00000398253.6
ENST00000573161.1
ZFP90 zinc finger protein
chr5_+_83471736 0.33 ENST00000265077.8
versican
chr8_+_78516329 0.33 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr14_-_21536884 0.33 ENST00000546363.5
spalt like transcription factor 2
chr2_+_30231524 0.33 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr10_-_68332878 0.33 ENST00000309049.8
phenazine biosynthesis like protein domain containing
chr11_+_114060204 0.32 ENST00000683318.1
zinc finger and BTB domain containing 16
chr6_-_46491431 0.32 ENST00000371374.6
regulator of calcineurin 2
chr11_+_114059755 0.32 ENST00000684295.1
zinc finger and BTB domain containing 16
chr5_-_147453888 0.32 ENST00000398514.7
dihydropyrimidinase like 3
chr5_-_111757382 0.32 ENST00000453526.6
ENST00000509427.5
neuronal regeneration related protein
chr12_+_94148553 0.32 ENST00000258526.9
plexin C1
chr14_-_91947654 0.31 ENST00000342058.9
fibulin 5
chr11_+_86800507 0.31 ENST00000533902.2
serine protease 23
chr3_+_69936583 0.30 ENST00000314557.10
ENST00000394351.9
melanocyte inducing transcription factor
chr17_-_64390852 0.30 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr5_-_111757549 0.30 ENST00000419114.6
neuronal regeneration related protein
chr14_-_91947383 0.30 ENST00000267620.14
fibulin 5
chr1_-_1358524 0.30 ENST00000445648.5
ENST00000309212.11
matrix remodeling associated 8
chr1_+_197917355 0.30 ENST00000367388.4
ENST00000367387.6
LIM homeobox 9
chr2_-_37671633 0.30 ENST00000295324.4
CDC42 effector protein 3
chrX_-_107717054 0.30 ENST00000503515.1
ENST00000372397.6
TSC22 domain family member 3
chr18_-_28177016 0.30 ENST00000430882.6
cadherin 2
chr2_+_209580024 0.29 ENST00000392194.5
microtubule associated protein 2
chr1_-_3531403 0.29 ENST00000294599.8
multiple EGF like domains 6
chrX_+_9912434 0.29 ENST00000418909.6
shroom family member 2
chr1_-_156859087 0.29 ENST00000368195.4
insulin receptor related receptor
chr8_-_107497909 0.29 ENST00000517746.6
angiopoietin 1
chr14_+_20999255 0.29 ENST00000554422.5
ENST00000298681.5
solute carrier family 39 member 2
chr4_+_123396785 0.29 ENST00000505319.5
ENST00000651917.1
ENST00000610581.4
ENST00000339241.1
sprouty RTK signaling antagonist 1
chr9_+_88388356 0.29 ENST00000375859.4
spindlin 1
chr1_-_1307861 0.29 ENST00000354700.10
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr3_-_58577367 0.29 ENST00000464064.5
ENST00000360997.7
family with sequence similarity 107 member A
chr21_+_25639251 0.29 ENST00000480456.6
junctional adhesion molecule 2
chr6_+_101393699 0.28 ENST00000369134.9
ENST00000684068.1
ENST00000683903.1
ENST00000681975.1
glutamate ionotropic receptor kainate type subunit 2
chr19_-_55180010 0.28 ENST00000589172.5
synaptotagmin 5
chr13_-_33185994 0.28 ENST00000255486.8
StAR related lipid transfer domain containing 13
chr11_-_70717994 0.28 ENST00000659264.1
SH3 and multiple ankyrin repeat domains 2
chr10_-_77090722 0.27 ENST00000638531.1
potassium calcium-activated channel subfamily M alpha 1
chr9_+_36036899 0.27 ENST00000377966.4
reversion inducing cysteine rich protein with kazal motifs
chr16_+_21599558 0.27 ENST00000396014.8
ENST00000358154.8
ENST00000615720.4
methyltransferase like 9
chr13_+_75760659 0.27 ENST00000526202.5
ENST00000465261.6
LIM domain 7
chr5_-_111757465 0.27 ENST00000446294.6
neuronal regeneration related protein
chr16_-_73048104 0.27 ENST00000268489.10
zinc finger homeobox 3
chr14_-_87993159 0.27 ENST00000393568.8
ENST00000261304.7
galactosylceramidase
chr9_+_36136752 0.27 ENST00000619700.1
GLI pathogenesis related 2
chr11_+_114059702 0.27 ENST00000335953.9
ENST00000684612.1
ENST00000682810.1
ENST00000544220.1
zinc finger and BTB domain containing 16
chrX_+_12975083 0.27 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr2_-_1744442 0.27 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr5_+_157266079 0.26 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
cytoplasmic FMR1 interacting protein 2
chr8_-_22693469 0.26 ENST00000317216.3
early growth response 3
chr6_+_125919296 0.26 ENST00000444128.2
nuclear receptor coactivator 7
chr9_+_36136703 0.26 ENST00000377960.9
ENST00000377959.5
GLI pathogenesis related 2
chr5_-_14871757 0.26 ENST00000284268.8
ANKH inorganic pyrophosphate transport regulator
chr16_+_55479188 0.26 ENST00000219070.9
matrix metallopeptidase 2
chr1_-_16980607 0.26 ENST00000375535.4
microfibril associated protein 2
chr19_+_7516081 0.26 ENST00000597229.2
zinc finger protein 358
chr21_+_25639272 0.26 ENST00000400532.5
ENST00000312957.9
junctional adhesion molecule 2
chr1_+_201739864 0.25 ENST00000367295.5
neuron navigator 1
chr1_+_185734362 0.25 ENST00000271588.9
hemicentin 1
chr2_-_165203870 0.25 ENST00000639244.1
ENST00000409101.7
ENST00000668657.1
sodium voltage-gated channel alpha subunit 3
chr7_+_71132123 0.25 ENST00000333538.10
polypeptide N-acetylgalactosaminyltransferase 17
chr5_+_120531464 0.25 ENST00000505123.5
proline rich 16
chr3_-_120450981 0.25 ENST00000424703.6
ENST00000469005.1
ENST00000295633.8
follistatin like 1
chr6_+_89080739 0.25 ENST00000369472.1
ENST00000336032.4
proline rich nuclear receptor coactivator 1
chr1_+_47333863 0.25 ENST00000471289.2
ENST00000450808.2
cytidine/uridine monophosphate kinase 1
chr4_-_5893075 0.25 ENST00000324989.12
collapsin response mediator protein 1
chr1_+_201888864 0.25 ENST00000362011.7
shisa family member 4
chr15_+_22094522 0.25 ENST00000328795.5
olfactory receptor family 4 subfamily N member 4
chr1_+_236142526 0.25 ENST00000366592.8
G protein-coupled receptor 137B
chr12_+_32107151 0.25 ENST00000548411.5
BICD cargo adaptor 1
chr21_-_26967057 0.25 ENST00000284987.6
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr6_+_125919210 0.24 ENST00000438495.6
nuclear receptor coactivator 7
chr9_-_70869029 0.24 ENST00000361823.9
ENST00000377101.5
ENST00000360823.6
ENST00000377105.5
transient receptor potential cation channel subfamily M member 3
chr12_+_53050014 0.24 ENST00000314250.11
tensin 2
chr12_+_53050179 0.24 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
tensin 2
chr3_-_48662877 0.24 ENST00000164024.5
cadherin EGF LAG seven-pass G-type receptor 3
chr5_+_76716182 0.24 ENST00000505600.1
coagulation factor II thrombin receptor
chr22_-_32255344 0.24 ENST00000266086.6
solute carrier family 5 member 4
chr18_-_28177934 0.24 ENST00000676445.1
cadherin 2
chr6_+_112236806 0.24 ENST00000588837.5
ENST00000590293.5
ENST00000585450.5
ENST00000629766.2
ENST00000590804.5
ENST00000590584.4
ENST00000628122.2
ENST00000627025.1
ENST00000590673.5
ENST00000585611.5
ENST00000587816.2
LAMA4 antisense RNA 1
novel ret finger protein-like 4B
chrX_+_12975216 0.24 ENST00000380635.5
thymosin beta 4 X-linked
chr3_-_115071333 0.24 ENST00000462705.5
zinc finger and BTB domain containing 20
chrX_+_52184874 0.24 ENST00000599522.7
ENST00000471932.6
MAGE family member D4
chr13_+_75788838 0.24 ENST00000497947.6
LIM domain 7
chr15_+_21651844 0.23 ENST00000623441.1
olfactory receptor family 4 subfamily N member 4C
chr2_+_148021404 0.23 ENST00000638043.2
methyl-CpG binding domain protein 5
chr9_-_129178247 0.23 ENST00000372491.4
immediate early response 5 like
chrX_+_55717796 0.23 ENST00000262850.7
Ras related GTP binding B
chr2_-_165204042 0.23 ENST00000283254.12
ENST00000453007.1
sodium voltage-gated channel alpha subunit 3
chr6_+_101181254 0.23 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr2_+_6917404 0.23 ENST00000320892.11
ring finger protein 144A
chr2_+_74458400 0.23 ENST00000393972.7
ENST00000233615.7
ENST00000409737.5
ENST00000428943.1
WW domain binding protein 1
chr17_-_19745369 0.23 ENST00000573368.5
ENST00000457500.6
aldehyde dehydrogenase 3 family member A1
chr4_-_7939789 0.23 ENST00000420658.6
ENST00000358461.6
actin filament associated protein 1
chr16_-_11636357 0.23 ENST00000576334.1
ENST00000574848.5
lipopolysaccharide induced TNF factor
chr22_-_24245059 0.23 ENST00000398292.3
ENST00000263112.11
ENST00000327365.10
ENST00000424217.1
gamma-glutamyltransferase 5
chr5_+_76716094 0.22 ENST00000319211.5
coagulation factor II thrombin receptor

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX3_SOX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1903465 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.3 0.8 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.3 0.8 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.3 0.8 GO:0035026 leading edge cell differentiation(GO:0035026)
0.2 0.6 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.2 1.3 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 0.5 GO:0006683 galactosylceramide catabolic process(GO:0006683)
0.2 1.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.2 0.5 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 0.9 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.5 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.8 GO:2000405 negative regulation of T cell migration(GO:2000405)
0.1 0.4 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.8 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 0.3 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 1.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 0.3 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 1.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.3 GO:0050904 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.1 0.5 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 0.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.3 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.6 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.5 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.5 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.2 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.1 0.7 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.7 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.2 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.4 GO:0061364 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) apoptotic process involved in luteolysis(GO:0061364)
0.1 0.4 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.2 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.3 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.3 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 1.0 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.0 0.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.1 GO:0061011 hepatic duct development(GO:0061011)
0.0 0.1 GO:0015847 putrescine transport(GO:0015847)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0061428 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 1.0 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.5 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.6 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.4 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.4 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.1 GO:0006113 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.0 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.8 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0030421 defecation(GO:0030421)
0.0 0.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0090155 negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059) inner medullary collecting duct development(GO:0072061)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.1 GO:2000481 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377) positive regulation of cAMP-dependent protein kinase activity(GO:2000481) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:1904177 regulation of adipose tissue development(GO:1904177) positive regulation of adipose tissue development(GO:1904179)
0.0 0.1 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 2.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
0.0 0.7 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.1 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.6 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0005999 xylulose biosynthetic process(GO:0005999)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.2 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.0 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.0 GO:2000174 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.0 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:1900276 negative regulation of phospholipase C activity(GO:1900275) regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0060346 bone trabecula formation(GO:0060346)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.2 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.0 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.6 GO:0090314 positive regulation of protein targeting to membrane(GO:0090314)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.0 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0061181 regulation of chondrocyte development(GO:0061181) negative regulation of chondrocyte development(GO:0061182)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.2 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.5 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.2 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846)
0.0 0.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.0 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.2 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.1 GO:0046208 spermine catabolic process(GO:0046208)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 0.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.1 GO:0071953 elastic fiber(GO:0071953)
0.1 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.8 GO:0044305 calyx of Held(GO:0044305)
0.1 1.3 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.1 0.6 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0097229 sperm end piece(GO:0097229)
0.1 1.3 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.6 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:1990769 proximal neuron projection(GO:1990769)
0.0 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.8 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0071754 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.5 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.0 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005124 scavenger receptor binding(GO:0005124)
0.2 0.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 0.5 GO:0004336 galactosylceramidase activity(GO:0004336)
0.2 0.6 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 0.7 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.5 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.4 GO:0000150 recombinase activity(GO:0000150)
0.1 0.5 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 1.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.0 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 1.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 1.1 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.1 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 1.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.1 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.0 GO:0070704 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.0 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.0 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.0 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.1 GO:0097108 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 4.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.2 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.0 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.6 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions