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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SOX9

Z-value: 0.51

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Transcription factors associated with SOX9

Gene Symbol Gene ID Gene Info
SOX9
ENSG00000125398.8 SRY-box transcription factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX9hg38_v1_chr17_+_72121012_72121033-0.167.0e-01Click!

Activity profile of SOX9 motif

Sorted Z-values of SOX9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_121873089 0.33 ENST00000651065.1
PTPRZ1
protein tyrosine phosphatase receptor type Z1
chr7_+_121873152 0.30 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
PTPRZ1
protein tyrosine phosphatase receptor type Z1
chr9_+_2622053 0.26 ENST00000681306.1
ENST00000681618.1
VLDLR
very low density lipoprotein receptor
chr10_-_104085847 0.24 ENST00000648076.2
COL17A1
collagen type XVII alpha 1 chain
chrX_-_117973579 0.23 ENST00000371878.5
KLHL13
kelch like family member 13
chr12_-_52493250 0.22 ENST00000330722.7
KRT6A
keratin 6A
chr16_+_788614 0.20 ENST00000262315.14
ENST00000455171.6
ENST00000317063.10
CHTF18
chromosome transmission fidelity factor 18
chr8_+_94641074 0.19 ENST00000423620.6
ESRP1
epithelial splicing regulatory protein 1
chr12_-_24902243 0.19 ENST00000538118.5
BCAT1
branched chain amino acid transaminase 1
chr4_+_112860981 0.18 ENST00000671704.1
ANK2
ankyrin 2
chr4_+_112860912 0.18 ENST00000671951.1
ANK2
ankyrin 2
chr4_+_112861053 0.18 ENST00000672221.1
ANK2
ankyrin 2
chr6_-_106975452 0.17 ENST00000619869.1
ENST00000619133.4
CD24
CD24 molecule
chr3_-_8644782 0.17 ENST00000544814.6
SSUH2
ssu-2 homolog
chr12_-_8662619 0.17 ENST00000544889.1
ENST00000543369.5
MFAP5
microfibril associated protein 5
chr20_+_20368096 0.16 ENST00000310227.3
INSM1
INSM transcriptional repressor 1
chr12_-_8662703 0.16 ENST00000535336.5
MFAP5
microfibril associated protein 5
chr6_-_106975309 0.16 ENST00000615659.1
CD24
CD24 molecule
chr6_-_106974721 0.15 ENST00000606017.2
ENST00000620405.1
CD24
CD24 molecule
chr3_+_189789643 0.15 ENST00000354600.10
TP63
tumor protein p63
chr12_+_77830886 0.14 ENST00000397909.7
ENST00000549464.5
NAV3
neuron navigator 3
chr9_+_78297143 0.14 ENST00000347159.6
PSAT1
phosphoserine aminotransferase 1
chr9_-_6645712 0.13 ENST00000321612.8
GLDC
glycine decarboxylase
chr12_-_95217373 0.13 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FGD6
FYVE, RhoGEF and PH domain containing 6
chr5_+_140834230 0.13 ENST00000356878.5
ENST00000525929.2
PCDHA7
protocadherin alpha 7
chr9_+_78297117 0.13 ENST00000376588.4
PSAT1
phosphoserine aminotransferase 1
chr14_-_70809494 0.13 ENST00000381250.8
ENST00000554752.7
ENST00000555993.6
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr8_-_80080816 0.13 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
TPD52
tumor protein D52
chr22_+_21632751 0.12 ENST00000292779.4
CCDC116
coiled-coil domain containing 116
chr5_-_16936231 0.12 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
MYO10
myosin X
chr9_+_27109393 0.12 ENST00000406359.8
TEK
TEK receptor tyrosine kinase
chr8_+_103819244 0.12 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
RIMS2
regulating synaptic membrane exocytosis 2
chr18_+_22169580 0.12 ENST00000269216.10
GATA6
GATA binding protein 6
chr6_+_33620329 0.11 ENST00000374316.9
ITPR3
inositol 1,4,5-trisphosphate receptor type 3
chr12_-_91058016 0.11 ENST00000266719.4
KERA
keratocan
chr15_+_40844018 0.11 ENST00000344051.8
ENST00000562057.6
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr8_+_101492423 0.10 ENST00000521085.1
ENST00000646743.1
GRHL2
grainyhead like transcription factor 2
chr10_-_102114935 0.10 ENST00000361198.9
LDB1
LIM domain binding 1
chr19_+_1249870 0.10 ENST00000591446.6
MIDN
midnolin
chr15_-_34367045 0.10 ENST00000617710.4
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr9_-_122227525 0.10 ENST00000373755.6
ENST00000373754.6
LHX6
LIM homeobox 6
chr15_-_34367159 0.10 ENST00000314891.11
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr17_-_39607876 0.10 ENST00000302584.5
NEUROD2
neuronal differentiation 2
chr3_+_189789734 0.09 ENST00000437221.5
ENST00000392463.6
ENST00000392461.7
ENST00000449992.5
ENST00000456148.1
TP63
tumor protein p63
chr1_+_156149657 0.09 ENST00000414683.5
SEMA4A
semaphorin 4A
chr3_-_65597886 0.09 ENST00000460329.6
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr1_+_61952036 0.09 ENST00000646453.1
ENST00000635137.1
PATJ
PATJ crumbs cell polarity complex component
chr2_-_61538180 0.09 ENST00000677150.1
ENST00000678182.1
ENST00000677928.1
ENST00000406957.5
XPO1
exportin 1
chr3_-_149333407 0.09 ENST00000470080.5
TM4SF18
transmembrane 4 L six family member 18
chr11_-_79441016 0.08 ENST00000278550.12
TENM4
teneurin transmembrane protein 4
chr8_-_109680812 0.08 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
SYBU
syntabulin
chr4_+_20251896 0.08 ENST00000504154.6
SLIT2
slit guidance ligand 2
chr15_+_85380625 0.08 ENST00000560302.5
AKAP13
A-kinase anchoring protein 13
chr22_-_46537593 0.08 ENST00000262738.9
ENST00000674500.2
CELSR1
cadherin EGF LAG seven-pass G-type receptor 1
chr10_+_89701580 0.08 ENST00000371728.8
ENST00000260753.8
KIF20B
kinesin family member 20B
chr3_-_123620496 0.08 ENST00000578202.1
MYLK
myosin light chain kinase
chr2_-_61538313 0.08 ENST00000677803.1
ENST00000677239.1
ENST00000401558.7
XPO1
exportin 1
chr1_+_160400543 0.08 ENST00000368061.3
VANGL2
VANGL planar cell polarity protein 2
chr2_-_61538290 0.08 ENST00000678790.1
XPO1
exportin 1
chr19_+_44891206 0.08 ENST00000405636.6
ENST00000252487.9
ENST00000592434.5
ENST00000589649.1
ENST00000426677.7
TOMM40
translocase of outer mitochondrial membrane 40
chr3_-_123620571 0.08 ENST00000583087.5
MYLK
myosin light chain kinase
chr8_-_42501224 0.08 ENST00000520262.6
ENST00000517366.1
SLC20A2
solute carrier family 20 member 2
chr12_-_85836372 0.08 ENST00000361228.5
RASSF9
Ras association domain family member 9
chr12_-_10098940 0.08 ENST00000420265.2
CLEC1A
C-type lectin domain family 1 member A
chr1_+_26177482 0.08 ENST00000361530.11
ENST00000374253.9
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr17_+_17042433 0.08 ENST00000651222.2
MPRIP
myosin phosphatase Rho interacting protein
chr4_+_53377749 0.08 ENST00000507166.5
ENSG00000282278.1
novel FIP1L1-PDGFRA fusion protein
chr19_+_10654327 0.08 ENST00000407004.7
ENST00000589998.5
ENST00000589600.5
ILF3
interleukin enhancer binding factor 3
chr11_-_46846233 0.07 ENST00000529230.6
ENST00000312055.9
CKAP5
cytoskeleton associated protein 5
chr7_-_11832190 0.07 ENST00000423059.9
ENST00000617773.1
THSD7A
thrombospondin type 1 domain containing 7A
chr2_-_61538516 0.07 ENST00000676771.1
ENST00000677814.1
ENST00000443240.5
ENST00000677556.1
ENST00000676553.1
XPO1
exportin 1
chr7_+_77538059 0.07 ENST00000435495.6
PTPN12
protein tyrosine phosphatase non-receptor type 12
chrX_+_68829009 0.07 ENST00000204961.5
EFNB1
ephrin B1
chr6_-_85644043 0.07 ENST00000678930.1
ENST00000678355.1
SYNCRIP
synaptotagmin binding cytoplasmic RNA interacting protein
chr7_+_26152188 0.07 ENST00000056233.4
NFE2L3
nuclear factor, erythroid 2 like 3
chr2_-_53970985 0.07 ENST00000404125.6
PSME4
proteasome activator subunit 4
chrX_-_24672654 0.07 ENST00000379145.5
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_156150008 0.07 ENST00000355014.6
SEMA4A
semaphorin 4A
chr3_+_14402576 0.07 ENST00000613060.4
SLC6A6
solute carrier family 6 member 6
chr11_+_73950985 0.07 ENST00000339764.6
DNAJB13
DnaJ heat shock protein family (Hsp40) member B13
chr3_+_39467672 0.07 ENST00000436143.6
ENST00000441980.6
ENST00000682069.1
ENST00000311042.10
MOBP
myelin associated oligodendrocyte basic protein
chr12_-_10098977 0.07 ENST00000315330.8
ENST00000457018.6
CLEC1A
C-type lectin domain family 1 member A
chr1_+_147902789 0.07 ENST00000369235.2
GJA8
gap junction protein alpha 8
chr1_-_243255170 0.07 ENST00000366542.6
CEP170
centrosomal protein 170
chr19_+_10654261 0.07 ENST00000449870.5
ILF3
interleukin enhancer binding factor 3
chr7_-_22193728 0.07 ENST00000620335.4
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr12_-_122500520 0.07 ENST00000540586.1
ENST00000543897.5
ZCCHC8
zinc finger CCHC-type containing 8
chr5_+_138352674 0.07 ENST00000314358.10
KDM3B
lysine demethylase 3B
chr1_-_243255320 0.07 ENST00000366544.5
ENST00000366543.5
CEP170
centrosomal protein 170
chr11_+_1390273 0.07 ENST00000526678.5
BRSK2
BR serine/threonine kinase 2
chr7_+_107470050 0.07 ENST00000304402.6
GPR22
G protein-coupled receptor 22
chr18_+_58863580 0.06 ENST00000586085.5
ENST00000589288.5
ZNF532
zinc finger protein 532
chr19_+_55376818 0.06 ENST00000291934.4
TMEM190
transmembrane protein 190
chr7_-_75738930 0.06 ENST00000336926.11
ENST00000434438.6
HIP1
huntingtin interacting protein 1
chr2_+_54456311 0.06 ENST00000615901.4
ENST00000356805.9
SPTBN1
spectrin beta, non-erythrocytic 1
chr20_-_51768327 0.06 ENST00000311637.9
ENST00000338821.6
ATP9A
ATPase phospholipid transporting 9A (putative)
chr6_+_32164586 0.06 ENST00000333845.11
ENST00000395512.5
ENST00000432129.1
EGFL8
EGF like domain multiple 8
chr12_-_122500924 0.06 ENST00000633063.3
ZCCHC8
zinc finger CCHC-type containing 8
chr7_-_22193824 0.06 ENST00000401957.6
RAPGEF5
Rap guanine nucleotide exchange factor 5
chr9_+_22446808 0.06 ENST00000325870.3
DMRTA1
DMRT like family A1
chr7_+_116672357 0.06 ENST00000456159.1
MET
MET proto-oncogene, receptor tyrosine kinase
chr8_+_24294107 0.06 ENST00000437154.6
ADAM28
ADAM metallopeptidase domain 28
chr2_-_157325808 0.06 ENST00000410096.6
ENST00000420719.6
ENST00000409216.5
ENST00000419116.2
ERMN
ermin
chr12_-_8662881 0.06 ENST00000433590.6
MFAP5
microfibril associated protein 5
chr21_-_17819386 0.06 ENST00000400559.7
ENST00000400558.7
C21orf91
chromosome 21 open reading frame 91
chr1_+_180928133 0.06 ENST00000367587.1
KIAA1614
KIAA1614
chr3_+_39467598 0.06 ENST00000428261.5
ENST00000420739.5
ENST00000415443.5
ENST00000447324.5
ENST00000383754.7
MOBP
myelin associated oligodendrocyte basic protein
chr1_+_61952283 0.06 ENST00000307297.8
PATJ
PATJ crumbs cell polarity complex component
chr12_-_122500947 0.06 ENST00000672018.1
ZCCHC8
zinc finger CCHC-type containing 8
chr16_+_3654683 0.06 ENST00000246949.10
DNASE1
deoxyribonuclease 1
chr1_-_225427897 0.06 ENST00000421383.1
ENST00000272163.9
LBR
lamin B receptor
chr17_+_59155726 0.06 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
PRR11
proline rich 11
chr15_+_40594241 0.06 ENST00000532056.5
ENST00000527044.5
ENST00000399668.7
KNL1
kinetochore scaffold 1
chr4_+_53377630 0.06 ENST00000337488.11
ENST00000358575.9
ENST00000507922.5
ENST00000306932.10
FIP1L1
factor interacting with PAPOLA and CPSF1
chr16_+_30923565 0.06 ENST00000338343.10
FBXL19
F-box and leucine rich repeat protein 19
chr15_+_40594001 0.06 ENST00000346991.9
ENST00000528975.5
KNL1
kinetochore scaffold 1
chr3_+_111998915 0.06 ENST00000478951.6
TAGLN3
transgelin 3
chr6_-_85643832 0.06 ENST00000677771.1
ENST00000676688.1
SYNCRIP
synaptotagmin binding cytoplasmic RNA interacting protein
chr1_-_16212598 0.06 ENST00000270747.8
ARHGEF19
Rho guanine nucleotide exchange factor 19
chr3_+_14402592 0.06 ENST00000622186.5
ENST00000621751.4
SLC6A6
solute carrier family 6 member 6
chr8_+_97644164 0.06 ENST00000336273.8
MTDH
metadherin
chr7_-_93226449 0.06 ENST00000394468.7
ENST00000453812.2
HEPACAM2
HEPACAM family member 2
chr9_+_121699328 0.06 ENST00000373782.7
DAB2IP
DAB2 interacting protein
chr2_-_200963633 0.06 ENST00000234296.7
ORC2
origin recognition complex subunit 2
chr11_-_116837586 0.06 ENST00000375320.5
ENST00000359492.6
ENST00000375329.6
ENST00000375323.5
ENST00000236850.5
APOA1
apolipoprotein A1
chr16_+_89923333 0.06 ENST00000315491.12
ENST00000555576.5
ENST00000554336.5
ENST00000553967.1
TUBB3
tubulin beta 3 class III
chr1_-_182672232 0.05 ENST00000508450.5
RGS8
regulator of G protein signaling 8
chr3_+_111999189 0.05 ENST00000455401.6
TAGLN3
transgelin 3
chrX_-_130903187 0.05 ENST00000432489.5
ENST00000394363.6
ENST00000338144.8
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr14_+_74763308 0.05 ENST00000325680.12
ENST00000552421.5
YLPM1
YLP motif containing 1
chr10_-_128126405 0.05 ENST00000368654.8
MKI67
marker of proliferation Ki-67
chr10_-_128126204 0.05 ENST00000368653.7
MKI67
marker of proliferation Ki-67
chr1_-_39901996 0.05 ENST00000397332.2
MYCL
MYCL proto-oncogene, bHLH transcription factor
chr1_-_39901861 0.05 ENST00000372816.3
ENST00000372815.1
MYCL
MYCL proto-oncogene, bHLH transcription factor
chr1_-_197146620 0.05 ENST00000367409.9
ENST00000680265.1
ASPM
assembly factor for spindle microtubules
chr1_-_197146688 0.05 ENST00000294732.11
ASPM
assembly factor for spindle microtubules
chr9_-_137302264 0.05 ENST00000356628.4
NRARP
NOTCH regulated ankyrin repeat protein
chrX_-_130903224 0.05 ENST00000370935.5
ENOX2
ecto-NOX disulfide-thiol exchanger 2
chr9_-_71768386 0.05 ENST00000377066.9
ENST00000377044.9
CEMIP2
cell migration inducing hyaluronidase 2
chr4_+_112231748 0.05 ENST00000274000.10
ENST00000309703.10
AP1AR
adaptor related protein complex 1 associated regulatory protein
chr9_+_131125578 0.05 ENST00000359428.10
ENST00000411637.6
ENST00000652454.1
NUP214
nucleoporin 214
chr22_+_49853801 0.05 ENST00000216268.6
ZBED4
zinc finger BED-type containing 4
chr7_+_155298561 0.05 ENST00000476756.1
INSIG1
insulin induced gene 1
chr8_-_20303955 0.05 ENST00000381569.5
LZTS1
leucine zipper tumor suppressor 1
chr1_+_248038172 0.05 ENST00000366479.4
OR2L2
olfactory receptor family 2 subfamily L member 2
chr11_+_60924452 0.05 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
TMEM132A
transmembrane protein 132A
chr19_+_7595830 0.05 ENST00000160298.9
ENST00000446248.4
CAMSAP3
calmodulin regulated spectrin associated protein family member 3
chr9_-_137070548 0.05 ENST00000409687.5
SAPCD2
suppressor APC domain containing 2
chr16_+_88570387 0.05 ENST00000452588.6
ENST00000301011.10
ZC3H18
zinc finger CCCH-type containing 18
chr3_+_189789672 0.05 ENST00000434928.5
TP63
tumor protein p63
chr1_-_116667668 0.05 ENST00000369486.8
ENST00000369483.5
IGSF3
immunoglobulin superfamily member 3
chr6_-_105403062 0.05 ENST00000652536.2
PREP
prolyl endopeptidase
chr22_+_23180365 0.05 ENST00000359540.7
ENST00000305877.13
BCR
BCR activator of RhoGEF and GTPase
chr3_-_186109067 0.05 ENST00000306376.10
ETV5
ETS variant transcription factor 5
chr3_+_124033356 0.05 ENST00000682506.1
KALRN
kalirin RhoGEF kinase
chr6_-_85643778 0.05 ENST00000676637.1
ENST00000678528.1
SYNCRIP
synaptotagmin binding cytoplasmic RNA interacting protein
chr9_+_27109135 0.05 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr10_-_60572599 0.05 ENST00000503366.5
ANK3
ankyrin 3
chr11_+_64186163 0.05 ENST00000305218.9
ENST00000538945.5
STIP1
stress induced phosphoprotein 1
chr6_-_75206044 0.05 ENST00000322507.13
COL12A1
collagen type XII alpha 1 chain
chr11_-_44950151 0.05 ENST00000533940.5
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr9_+_4792971 0.05 ENST00000381732.3
ENST00000442869.5
RCL1
RNA terminal phosphate cyclase like 1
chr9_+_105700953 0.05 ENST00000374688.5
TMEM38B
transmembrane protein 38B
chr11_+_67391975 0.05 ENST00000307980.7
RAD9A
RAD9 checkpoint clamp component A
chr18_-_13915531 0.05 ENST00000327606.4
MC2R
melanocortin 2 receptor
chrX_-_38220824 0.05 ENST00000378533.4
ENST00000432886.6
ENST00000544439.5
ENST00000538295.5
SRPX
sushi repeat containing protein X-linked
chr9_+_72577939 0.05 ENST00000645773.1
TMC1
transmembrane channel like 1
chr10_+_123135938 0.05 ENST00000357878.7
HMX3
H6 family homeobox 3
chr19_-_17264718 0.05 ENST00000431146.6
ENST00000594190.5
USHBP1
USH1 protein network component harmonin binding protein 1
chr12_+_69585666 0.05 ENST00000543146.2
CCT2
chaperonin containing TCP1 subunit 2
chr1_-_169485931 0.05 ENST00000367804.4
ENST00000646596.1
ENST00000236137.10
SLC19A2
solute carrier family 19 member 2
chr7_+_5592805 0.05 ENST00000382361.8
FSCN1
fascin actin-bundling protein 1
chr7_-_140176970 0.05 ENST00000397560.7
KDM7A
lysine demethylase 7A
chr17_+_7857695 0.05 ENST00000571846.5
CYB5D1
cytochrome b5 domain containing 1
chr11_-_119729158 0.05 ENST00000264025.8
NECTIN1
nectin cell adhesion molecule 1
chrM_+_4467 0.05 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr7_+_2631978 0.05 ENST00000258796.12
TTYH3
tweety family member 3
chr12_-_23951020 0.05 ENST00000441133.2
ENST00000545921.5
SOX5
SRY-box transcription factor 5
chr8_-_100953331 0.05 ENST00000353245.7
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr6_-_112087451 0.05 ENST00000368662.10
TUBE1
tubulin epsilon 1
chr7_-_151227035 0.05 ENST00000441774.1
ENST00000287844.7
ENST00000222388.6
ABCF2
ABCF2-H2BE1
ATP binding cassette subfamily F member 2
ABCF2-H2BE1 readthrough
chr1_+_200739542 0.05 ENST00000358823.6
CAMSAP2
calmodulin regulated spectrin associated protein family member 2
chr4_-_82429402 0.05 ENST00000602300.5
HNRNPDL
heterogeneous nuclear ribonucleoprotein D like
chr6_-_53348902 0.04 ENST00000370913.5
ENST00000304434.11
ELOVL5
ELOVL fatty acid elongase 5
chr16_-_48247533 0.04 ENST00000356608.7
ENST00000569991.1
ABCC11
ATP binding cassette subfamily C member 11
chr9_+_131125973 0.04 ENST00000651639.1
ENST00000451030.5
ENST00000531584.1
NUP214
nucleoporin 214
chr8_-_100952918 0.04 ENST00000395957.6
ENST00000395948.6
ENST00000457309.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr7_+_116672187 0.04 ENST00000318493.11
ENST00000397752.8
MET
MET proto-oncogene, receptor tyrosine kinase
chr16_-_27549887 0.04 ENST00000561623.5
ENST00000356183.9
GTF3C1
general transcription factor IIIC subunit 1
chr14_-_21048431 0.04 ENST00000555026.5
NDRG2
NDRG family member 2
chr7_-_149028651 0.04 ENST00000286091.9
PDIA4
protein disulfide isomerase family A member 4
chr5_-_43313403 0.04 ENST00000325110.11
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr5_+_51383394 0.04 ENST00000230658.12
ISL1
ISL LIM homeobox 1
chr7_-_16881967 0.04 ENST00000402239.7
ENST00000310398.7
ENST00000414935.1
AGR3
anterior gradient 3, protein disulphide isomerase family member
chrX_+_83508284 0.04 ENST00000644024.2
POU3F4
POU class 3 homeobox 4
chr17_-_51046868 0.04 ENST00000510283.5
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr11_+_64186219 0.04 ENST00000543847.1
STIP1
stress induced phosphoprotein 1
chr7_+_107583919 0.04 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr11_+_119085200 0.04 ENST00000650101.1
HMBS
hydroxymethylbilane synthase
chr2_-_55050556 0.04 ENST00000394611.6
RTN4
reticulon 4

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0032600 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.1 0.3 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.2 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.2 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.1 0.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.1 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.0 0.2 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.6 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.3 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.1 GO:0016476 calcium-dependent cell-matrix adhesion(GO:0016340) regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.0 GO:0097272 ammonia homeostasis(GO:0097272) urea homeostasis(GO:0097274)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.0 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.0 0.0 GO:1901258 cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.0 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.0 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.0 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:2000586 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.0 0.0 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.0 GO:1903004 flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0072534 perineuronal net(GO:0072534)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.0 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.0 GO:0044393 microspike(GO:0044393)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.2 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247) cholestenol delta-isomerase activity(GO:0047750)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.0 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0043273 CTPase activity(GO:0043273)
0.0 0.0 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.0 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)