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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for SPIC

Z-value: 1.56

Motif logo

Transcription factors associated with SPIC

Gene Symbol Gene ID Gene Info
ENSG00000166211.8 Spi-C transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIChg38_v1_chr12_+_101475319_1014753400.167.1e-01Click!

Activity profile of SPIC motif

Sorted Z-values of SPIC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_68644988 2.93 ENST00000429102.6
cadherin 3
chr19_-_50952942 2.24 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr18_+_23949847 2.03 ENST00000588004.1
laminin subunit alpha 3
chr2_-_112836702 1.86 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr7_-_143408848 1.76 ENST00000275815.4
EPH receptor A1
chr15_+_40844018 1.63 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr10_-_97401277 1.61 ENST00000315563.10
ENST00000370992.9
ENST00000414986.5
ribosomal RNA processing 12 homolog
chr19_-_50953063 1.53 ENST00000391809.6
kallikrein related peptidase 5
chr3_-_111595339 1.52 ENST00000317012.5
zinc finger BED-type containing 2
chr19_-_50953093 1.51 ENST00000593428.5
kallikrein related peptidase 5
chr1_-_183590876 1.50 ENST00000367536.5
neutrophil cytosolic factor 2
chr11_+_1840168 1.37 ENST00000381905.3
troponin I2, fast skeletal type
chr1_-_175192769 1.37 ENST00000423313.6
KIAA0040
chr12_-_51391398 1.35 ENST00000356317.8
ENST00000603188.5
ENST00000604847.5
ENST00000604506.5
polypeptide N-acetylgalactosaminyltransferase 6
chr10_-_96271508 1.31 ENST00000427367.6
ENST00000413476.6
ENST00000371176.6
B cell linker
chr13_+_36431510 1.30 ENST00000630422.2
cyclin A1
chr11_-_79441016 1.28 ENST00000278550.12
teneurin transmembrane protein 4
chr1_+_161707205 1.22 ENST00000367957.7
Fc receptor like A
chr6_+_116461364 1.20 ENST00000368606.7
ENST00000368605.3
calcium homeostasis modulator family member 6
chr1_+_161707244 1.16 ENST00000349527.8
ENST00000294796.8
ENST00000309691.10
ENST00000367953.7
ENST00000367950.2
Fc receptor like A
chr1_+_161707222 1.12 ENST00000236938.12
Fc receptor like A
chr10_-_96271553 1.08 ENST00000224337.10
B cell linker
chr6_+_106086316 1.07 ENST00000369091.6
ENST00000369096.9
PR/SET domain 1
chr16_+_30183595 1.06 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
coronin 1A
chr3_+_130894050 1.03 ENST00000510168.6
ATPase secretory pathway Ca2+ transporting 1
chr1_+_233327710 1.02 ENST00000366624.8
mitogen-activated protein kinase kinase kinase 21
chr2_+_162318884 1.01 ENST00000446271.5
ENST00000429691.6
grancalcin
chr1_-_99766620 1.01 ENST00000646001.2
ferric chelate reductase 1
chr3_+_130894157 1.00 ENST00000504948.5
ENST00000513801.5
ENST00000505072.5
ATPase secretory pathway Ca2+ transporting 1
chrX_+_30215551 1.00 ENST00000378988.5
MAGE family member B2
chrX_+_71910818 0.99 ENST00000633930.1
NHS like 2
chr13_-_46182136 0.97 ENST00000323076.7
lymphocyte cytosolic protein 1
chr17_-_45410414 0.97 ENST00000532038.5
ENST00000528677.1
Rho GTPase activating protein 27
chr3_-_116444983 0.97 ENST00000333617.8
limbic system associated membrane protein
chr4_-_88231322 0.96 ENST00000515655.5
ATP binding cassette subfamily G member 2 (Junior blood group)
chr2_+_101991953 0.96 ENST00000332549.8
interleukin 1 receptor type 2
chr3_+_130893959 0.94 ENST00000508532.5
ENST00000533801.6
ATPase secretory pathway Ca2+ transporting 1
chr12_+_50924005 0.90 ENST00000550502.1
methyltransferase like 7A
chr1_-_183590596 0.90 ENST00000418089.5
ENST00000413720.5
neutrophil cytosolic factor 2
chr6_-_11779606 0.90 ENST00000506810.1
androgen dependent TFPI regulating protein
chr11_+_1839602 0.90 ENST00000617947.4
ENST00000252898.11
troponin I2, fast skeletal type
chr4_-_121381007 0.90 ENST00000394427.3
pyroglutamylated RFamide peptide receptor
chr8_-_126557691 0.89 ENST00000652209.1
LRAT domain containing 2
chr1_-_183590439 0.88 ENST00000367535.8
neutrophil cytosolic factor 2
chr4_+_83536097 0.87 ENST00000395226.6
ENST00000264409.5
glycerol-3-phosphate acyltransferase 3
chr1_+_24319342 0.87 ENST00000361548.9
grainyhead like transcription factor 3
chr16_+_82035245 0.86 ENST00000199936.9
hydroxysteroid 17-beta dehydrogenase 2
chr8_-_123042244 0.84 ENST00000259512.9
ENST00000419562.6
derlin 1
chr4_-_80073465 0.84 ENST00000404191.5
ANTXR cell adhesion molecule 2
chr4_-_80073057 0.82 ENST00000681710.1
ANTXR cell adhesion molecule 2
chr2_+_113127588 0.79 ENST00000409930.4
interleukin 1 receptor antagonist
chr5_-_78985951 0.79 ENST00000396151.7
arylsulfatase B
chr12_-_8066331 0.78 ENST00000546241.1
ENST00000307637.5
complement C3a receptor 1
chr12_+_112938284 0.78 ENST00000681346.1
2'-5'-oligoadenylate synthetase 3
chr15_+_74541200 0.77 ENST00000622429.1
ENST00000346246.10
AT-rich interaction domain 3B
chr2_+_147844601 0.77 ENST00000404590.1
activin A receptor type 2A
chr4_-_80073170 0.77 ENST00000403729.7
ANTXR cell adhesion molecule 2
chr8_-_123042122 0.77 ENST00000405944.7
derlin 1
chr2_+_105851748 0.76 ENST00000425756.1
ENST00000393349.2
NCK adaptor protein 2
chr2_-_162318475 0.76 ENST00000648433.1
interferon induced with helicase C domain 1
chr6_+_111259474 0.76 ENST00000672554.1
ENST00000673024.1
major facilitator superfamily domain containing 4B
chr12_-_54384687 0.76 ENST00000550120.1
ENST00000547210.5
ENST00000394313.7
zinc finger protein 385A
chr4_+_8199363 0.75 ENST00000382521.7
ENST00000457650.7
SH3 domain and tetratricopeptide repeats 1
chr3_+_130894382 0.74 ENST00000509662.5
ENST00000328560.12
ENST00000428331.6
ENST00000359644.7
ENST00000422190.6
ATPase secretory pathway Ca2+ transporting 1
chr9_-_33473884 0.74 ENST00000297990.9
ENST00000353159.6
ENST00000379471.3
nucleolar protein 6
chr1_+_161706949 0.74 ENST00000350710.3
ENST00000367949.6
ENST00000367959.6
ENST00000540521.5
ENST00000546024.5
ENST00000674251.1
ENST00000674323.1
Fc receptor like A
chr17_-_7290392 0.74 ENST00000571464.1
Y-box binding protein 2
chr11_-_120123026 0.73 ENST00000533302.5
tripartite motif containing 29
chr6_+_111259294 0.73 ENST00000672303.1
ENST00000671876.2
ENST00000368847.5
major facilitator superfamily domain containing 4B
chr4_+_8199239 0.73 ENST00000245105.8
SH3 domain and tetratricopeptide repeats 1
chr12_-_95217373 0.73 ENST00000549499.1
ENST00000546711.5
ENST00000343958.9
FYVE, RhoGEF and PH domain containing 6
chr8_+_32721823 0.72 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chr6_+_26500296 0.72 ENST00000684113.1
butyrophilin subfamily 1 member A1
chr19_-_54173151 0.72 ENST00000619895.5
transmembrane channel like 4
chr6_-_136250260 0.71 ENST00000418509.2
ENST00000420702.6
ENST00000451457.6
mitochondrial fission regulator 2
chr19_+_1067144 0.70 ENST00000313093.7
Rho GTPase activating protein 45
chr16_+_69339758 0.70 ENST00000254940.10
ENST00000254941.6
nucleolar pre-rRNA processing protein NIP7
chr4_+_102501885 0.70 ENST00000505458.5
nuclear factor kappa B subunit 1
chr19_+_1067493 0.69 ENST00000586866.5
Rho GTPase activating protein 45
chr14_+_94174284 0.68 ENST00000304338.8
protein phosphatase 4 regulatory subunit 4
chrX_+_139530730 0.67 ENST00000218099.7
coagulation factor IX
chr7_-_91880672 0.67 ENST00000456229.1
ENST00000442961.1
ENST00000406735.6
ENST00000419292.1
ENST00000351870.8
mitochondrial transcription termination factor 1
chr17_-_31314040 0.66 ENST00000330927.5
ecotropic viral integration site 2B
chr19_+_49335396 0.65 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr19_+_1067272 0.65 ENST00000590214.5
Rho GTPase activating protein 45
chr6_+_14117764 0.64 ENST00000379153.4
CD83 molecule
chr2_-_20225433 0.64 ENST00000381150.5
syndecan 1
chr11_-_72752376 0.63 ENST00000393609.8
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_-_50968125 0.63 ENST00000594641.1
kallikrein related peptidase 6
chr19_-_54173190 0.62 ENST00000617472.4
transmembrane channel like 4
chr3_+_124584625 0.62 ENST00000291478.9
ENST00000682363.1
ENST00000454902.1
kalirin RhoGEF kinase
chr8_-_85341705 0.61 ENST00000517618.5
carbonic anhydrase 1
chr1_+_43974902 0.61 ENST00000532642.5
ENST00000236067.8
ENST00000471859.6
ENST00000472174.7
ATPase H+ transporting V0 subunit b
chr15_+_80695277 0.61 ENST00000258884.5
ENST00000558464.1
abhydrolase domain containing 17C, depalmitoylase
chr12_-_94650506 0.60 ENST00000261226.9
transmembrane and coiled-coil domain family 3
chr2_+_168456215 0.60 ENST00000392687.4
ENST00000305747.11
ceramide synthase 6
chr16_-_88651015 0.59 ENST00000568278.1
ENST00000569359.5
ENST00000567174.5
ENST00000261623.8
cytochrome b-245 alpha chain
chr1_+_115976488 0.58 ENST00000369503.9
solute carrier family 22 member 15
chr21_-_44920918 0.58 ENST00000522688.5
integrin subunit beta 2
chr2_+_147844488 0.58 ENST00000535787.5
activin A receptor type 2A
chr17_-_76585808 0.57 ENST00000225276.10
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr14_-_22815856 0.57 ENST00000554758.1
ENST00000397528.8
solute carrier family 7 member 7
chr14_-_22815801 0.57 ENST00000397532.9
solute carrier family 7 member 7
chr2_+_102355750 0.57 ENST00000233957.7
interleukin 18 receptor 1
chr9_-_5304713 0.57 ENST00000381627.4
relaxin 2
chr20_+_1894462 0.56 ENST00000622179.4
signal regulatory protein alpha
chr3_+_187024614 0.56 ENST00000416235.6
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr2_+_102355881 0.56 ENST00000409599.5
interleukin 18 receptor 1
chr1_-_156816738 0.54 ENST00000368198.7
SH2 domain containing 2A
chr1_-_161045961 0.54 ENST00000368021.7
upstream transcription factor 1
chr15_+_76995118 0.54 ENST00000558012.6
ENST00000379595.7
proline-serine-threonine phosphatase interacting protein 1
chr5_-_140633690 0.53 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr4_-_109801978 0.53 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr3_+_122077850 0.53 ENST00000482356.5
ENST00000393627.6
CD86 molecule
chr8_-_18083184 0.52 ENST00000636269.1
N-acylsphingosine amidohydrolase 1
chr1_-_161044941 0.52 ENST00000368020.5
upstream transcription factor 1
chr4_+_102501298 0.52 ENST00000394820.8
ENST00000226574.9
ENST00000511926.5
ENST00000507079.5
nuclear factor kappa B subunit 1
chr3_-_20186127 0.52 ENST00000425061.5
ENST00000443724.5
ENST00000421451.5
ENST00000452020.5
ENST00000417364.1
ENST00000306698.6
ENST00000419233.6
ENST00000263753.8
ENST00000437051.5
ENST00000442720.5
ENST00000412997.6
shugoshin 1
chrX_-_40735476 0.51 ENST00000324817.6
mediator complex subunit 14
chr6_+_139028680 0.50 ENST00000367660.4
ABRA C-terminal like
chr8_-_103415085 0.50 ENST00000297578.9
solute carrier family 25 member 32
chr17_+_44345291 0.49 ENST00000593167.5
ENST00000585512.5
ENST00000591740.5
ENST00000592783.5
ENST00000587387.5
ENST00000588237.5
ENST00000053867.8
ENST00000589265.5
granulin precursor
chr18_-_77127935 0.49 ENST00000581878.5
myelin basic protein
chr18_-_55586092 0.48 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr18_-_55585773 0.48 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
transcription factor 4
chr16_-_23641270 0.48 ENST00000568219.5
ENST00000261584.9
partner and localizer of BRCA2
chr5_+_38845824 0.46 ENST00000502536.5
oncostatin M receptor
chrX_-_119837918 0.46 ENST00000636792.1
UPF3B regulator of nonsense mediated mRNA decay
chr11_+_57667974 0.45 ENST00000528177.5
ENST00000287169.8
zinc finger DHHC-type palmitoyltransferase 5
chr11_-_60952559 0.45 ENST00000538739.2
solute carrier family 15 member 3
chr17_+_18781155 0.45 ENST00000574226.5
ENST00000575261.5
ENST00000307767.13
trans-golgi network vesicle protein 23 homolog B
chr10_+_43606415 0.45 ENST00000430885.5
ENST00000374435.3
ENST00000361807.8
zinc finger protein 485
chr3_+_148865288 0.44 ENST00000296046.4
carboxypeptidase A3
chr11_-_60952067 0.44 ENST00000681275.1
solute carrier family 15 member 3
chr14_+_77457861 0.44 ENST00000555133.5
activator of HSP90 ATPase activity 1
chr3_+_57556244 0.44 ENST00000311180.9
ENST00000487257.1
phosphodiesterase 12
chr11_-_123654939 0.44 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr3_+_32391694 0.43 ENST00000349718.8
CKLF like MARVEL transmembrane domain containing 7
chr11_-_57426745 0.43 ENST00000529554.5
solute carrier family 43 member 3
chr7_+_128937917 0.43 ENST00000357234.10
ENST00000613821.4
ENST00000477535.5
ENST00000479582.5
ENST00000464557.5
ENST00000402030.6
interferon regulatory factor 5
chr5_+_83077559 0.42 ENST00000511817.1
X-ray repair cross complementing 4
chr2_-_180007254 0.42 ENST00000410053.8
CWC22 spliceosome associated protein homolog
chr1_+_43969970 0.42 ENST00000255108.8
ENST00000396758.6
diphthamide biosynthesis 2
chr14_+_77458032 0.42 ENST00000535854.6
ENST00000555517.1
ENST00000216479.8
activator of HSP90 ATPase activity 1
chr1_-_246566238 0.42 ENST00000366514.5
transcription factor B2, mitochondrial
chr17_+_2056073 0.42 ENST00000576444.1
ENST00000322941.3
HIC ZBTB transcriptional repressor 1
chr1_-_212414815 0.41 ENST00000261455.9
ENST00000535273.2
proton activated chloride channel 1
chr16_+_81495340 0.41 ENST00000539778.6
c-Maf inducing protein
chr4_-_86101922 0.41 ENST00000472236.5
ENST00000641881.1
mitogen-activated protein kinase 10
chr3_-_121545962 0.41 ENST00000264233.6
DNA polymerase theta
chr7_-_108569453 0.40 ENST00000313516.5
THAP domain containing 5
chr3_+_32391871 0.40 ENST00000465248.1
CKLF like MARVEL transmembrane domain containing 7
chr12_+_6946468 0.40 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr12_+_12070932 0.40 ENST00000308721.9
BCL2 like 14
chr22_+_46620380 0.40 ENST00000406902.6
GRAM domain containing 4
chr1_-_46604283 0.40 ENST00000341183.9
ENST00000649800.1
ENST00000650026.1
ENST00000650508.1
ENST00000496619.6
MAPK interacting serine/threonine kinase 1
chr6_-_150025520 0.40 ENST00000367341.6
ENST00000286380.2
retinoic acid early transcript 1L
chr19_-_46787278 0.39 ENST00000412532.6
solute carrier family 1 member 5
chr4_-_102760914 0.39 ENST00000505239.1
ENST00000647097.2
mannosidase beta
chr3_+_130850585 0.39 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr5_+_83077498 0.39 ENST00000282268.7
ENST00000338635.10
ENST00000396027.9
X-ray repair cross complementing 4
chr11_+_100687279 0.39 ENST00000298815.13
Rho GTPase activating protein 42
chr8_-_85341659 0.39 ENST00000522389.5
carbonic anhydrase 1
chr3_-_156555083 0.39 ENST00000265044.7
ENST00000476217.5
signal sequence receptor subunit 3
chr17_+_18781250 0.39 ENST00000476139.5
trans-golgi network vesicle protein 23 homolog B
chr2_+_218710931 0.38 ENST00000442769.5
ENST00000424644.1
tubulin tyrosine ligase like 4
chr19_-_16542415 0.38 ENST00000198939.6
ENST00000546361.7
calcium homeostasis endoplasmic reticulum protein
chr2_+_112542413 0.38 ENST00000417433.6
ENST00000263331.10
RNA polymerase I subunit B
chr6_+_12290353 0.38 ENST00000379375.6
endothelin 1
chr20_-_45912047 0.38 ENST00000477313.5
ENST00000354050.8
ENST00000372431.8
ENST00000420868.2
phospholipid transfer protein
chr11_-_65117639 0.38 ENST00000528598.1
ENST00000310597.6
zinc finger HIT-type containing 2
chr1_-_46604214 0.38 ENST00000371946.9
ENST00000428112.7
ENST00000529170.6
ENST00000371945.10
MAPK interacting serine/threonine kinase 1
chr12_+_123602085 0.38 ENST00000238146.9
ENST00000538744.5
DEAD-box helicase 55
chr14_+_69879408 0.38 ENST00000361956.8
ENST00000381280.4
SPARC related modular calcium binding 1
chr10_-_129964240 0.38 ENST00000440978.2
ENST00000355311.10
EBF transcription factor 3
chr3_+_46242453 0.37 ENST00000452454.1
ENST00000395940.3
ENST00000457243.1
C-C motif chemokine receptor 3
chr4_-_110198650 0.37 ENST00000394607.7
ELOVL fatty acid elongase 6
chr2_-_162318613 0.37 ENST00000649979.2
ENST00000421365.2
interferon induced with helicase C domain 1
chr8_+_74824526 0.37 ENST00000649643.1
ENST00000260113.7
peptidase inhibitor 15
chr1_+_212035717 0.37 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr19_-_38426195 0.37 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RAS guanyl releasing protein 4
chr4_-_110198579 0.36 ENST00000302274.8
ELOVL fatty acid elongase 6
chr1_+_152719522 0.36 ENST00000368775.3
chromosome 1 open reading frame 68
chr11_+_7605719 0.36 ENST00000530181.5
PPFIA binding protein 2
chr6_+_110982028 0.36 ENST00000441448.7
ribosome production factor 2 homolog
chr11_-_59212869 0.36 ENST00000361050.4
macrophage expressed 1
chr12_+_131929194 0.36 ENST00000443358.6
pseudouridine synthase 1
chr17_+_74431338 0.36 ENST00000342648.9
ENST00000652232.1
ENST00000481232.2
G protein-coupled receptor class C group 5 member C
chr5_-_74767105 0.35 ENST00000509430.5
ENST00000296805.8
ENST00000345239.6
ENST00000427854.6
ENST00000506778.1
GTP dependent ribosome recycling factor mitochondrial 2
chr19_-_8577405 0.35 ENST00000596675.1
ENST00000644032.2
ENST00000613525.4
myosin IF
chr11_+_112176364 0.35 ENST00000526088.5
ENST00000532593.5
ENST00000531169.5
beta-carotene oxygenase 2
chr1_+_75786246 0.34 ENST00000319942.8
Rab geranylgeranyltransferase subunit beta
chr11_+_59787067 0.34 ENST00000528805.1
syntaxin 3
chr12_-_124863783 0.34 ENST00000546215.5
ENST00000415380.6
ENST00000545493.1
ENST00000261693.11
ENST00000680596.1
scavenger receptor class B member 1
chr14_+_51240205 0.34 ENST00000457354.7
thioredoxin related transmembrane protein 1
chr4_-_102760976 0.34 ENST00000644159.1
ENST00000642252.1
mannosidase beta
chr14_+_94174334 0.34 ENST00000328839.3
protein phosphatase 4 regulatory subunit 4
chr22_+_36913620 0.34 ENST00000403662.8
ENST00000262825.9
colony stimulating factor 2 receptor subunit beta
chr22_+_41800662 0.34 ENST00000402061.7
ENST00000255784.6
coiled-coil domain containing 134
chr3_+_122077776 0.34 ENST00000264468.9
CD86 molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912) negative regulation of hair follicle maturation(GO:0048817) regulation of melanosome transport(GO:1902908)
0.9 5.3 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.7 4.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.6 1.9 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.4 1.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.4 1.1 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.3 0.9 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.3 1.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.3 0.9 GO:0043017 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.3 1.6 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.3 0.8 GO:0061580 colon epithelial cell migration(GO:0061580)
0.2 0.7 GO:0009386 translational attenuation(GO:0009386)
0.2 1.2 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.2 1.0 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 1.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 0.7 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.2 0.8 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.6 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 1.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 0.8 GO:0070889 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 1.3 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 1.1 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.2 1.3 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.2 1.1 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2 0.6 GO:0048627 myoblast development(GO:0048627)
0.2 0.6 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.2 0.9 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.2 0.5 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.5 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.8 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 0.4 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.5 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.4 GO:0016108 tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247)
0.1 0.3 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.1 1.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.6 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.3 GO:1990641 response to iron ion starvation(GO:1990641)
0.1 1.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.4 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 3.6 GO:0045730 respiratory burst(GO:0045730)
0.1 0.3 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.1 0.5 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.5 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 1.0 GO:0015886 heme transport(GO:0015886)
0.1 0.7 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 1.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.4 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 2.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.1 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.6 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.3 GO:1904379 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.4 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.2 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.3 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.2 GO:1902263 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.6 GO:0046959 habituation(GO:0046959)
0.1 0.6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.7 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.3 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) positive regulation of muscle adaptation(GO:0014744)
0.0 0.1 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:0003350 pulmonary myocardium development(GO:0003350)
0.0 0.1 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.0 0.8 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 1.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.2 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.9 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.2 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.0 2.4 GO:1901998 toxin transport(GO:1901998)
0.0 1.4 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:0061738 late endosomal microautophagy(GO:0061738)
0.0 0.6 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 1.1 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0002396 MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399)
0.0 2.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.4 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 1.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 1.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.9 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.0 0.4 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.0 GO:0048630 skeletal muscle tissue growth(GO:0048630) regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:0090197 positive regulation of chemokine secretion(GO:0090197)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.3 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.1 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 1.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 1.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.0 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.3 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.0 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.6 GO:0051031 tRNA transport(GO:0051031)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 1.0 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.0 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.4 GO:0071800 podosome assembly(GO:0071800)
0.0 0.4 GO:0001771 immunological synapse formation(GO:0001771)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.0 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.2 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.3 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.4 GO:0015991 vacuolar acidification(GO:0007035) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.4 3.7 GO:0032010 phagolysosome(GO:0032010)
0.3 1.3 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.3 1.6 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.3 2.0 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.8 GO:0032807 DNA ligase IV complex(GO:0032807)
0.2 0.5 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 1.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.4 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 2.3 GO:0005861 troponin complex(GO:0005861)
0.1 1.1 GO:0016589 NURF complex(GO:0016589)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.3 GO:0071920 cleavage body(GO:0071920)
0.1 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 2.3 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.1 0.2 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 1.0 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 3.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 3.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.4 GO:0030684 preribosome(GO:0030684)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 1.2 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 2.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 3.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.3 3.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 0.9 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.3 0.9 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 0.8 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.2 1.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 0.8 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 1.0 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 1.2 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 1.4 GO:0098821 BMP receptor activity(GO:0098821)
0.2 2.3 GO:0031014 troponin T binding(GO:0031014)
0.2 1.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 1.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.4 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 2.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 3.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.4 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.3 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 1.0 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.5 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 1.0 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.3 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)
0.1 0.3 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.1 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 1.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.5 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.2 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.8 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 0.6 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.2 GO:0004040 amidase activity(GO:0004040)
0.1 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.0 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.0 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 2.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 1.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 1.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.5 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 2.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0033749 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.0 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.6 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 5.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0047012 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.0 0.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.4 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.1 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.9 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 2.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 3.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 0.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 2.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 2.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.4 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 2.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 3.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis