Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
SREBF2 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000198911.12	sterol regulatory element binding transcription factor 2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SREBF2	hg38_v1_chr22_+_41833079_41833142	0.35	4.0e-01	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_+_103500696 Show fit	0.22	ENST00000666250.1 ENST00000668113.1 ENST00000504942.6 ENST00000632716.1	RIMS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	regulating synaptic membrane exocytosis 2
chr1_+_55039511 Show fit	0.17	ENST00000302118.5	PCSK9 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proprotein convertase subtilisin/kexin type 9
chr10_-_114684612 Show fit	0.08	ENST00000533213.6 ENST00000369252.8	ABLIM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin binding LIM protein 1
chr10_-_114684457 Show fit	0.08	ENST00000392955.7	ABLIM1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	actin binding LIM protein 1
chr3_+_50269140 Show fit	0.07	ENST00000616701.5 ENST00000433753.4 ENST00000611067.4	SEMA3B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	semaphorin 3B
chr8_-_123416327 Show fit	0.06	ENST00000521903.5	ATAD2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATPase family AAA domain containing 2
chr17_-_41118369 Show fit	0.06	ENST00000391413.4	KRTAP4-11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin associated protein 4-11
chrX_-_153971169 Show fit	0.06	ENST00000369984.4	HCFC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	host cell factor C1
chrX_-_153971810 Show fit	0.06	ENST00000310441.12	HCFC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	host cell factor C1
chr8_-_17722217 Show fit	0.05	ENST00000381861.7	MTUS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule associated scaffold protein 1
chr15_+_47184076 Show fit	0.05	ENST00000558014.5	SEMA6D Links Ensembl NCBI GeneCards UniProt NextProt Show fit	semaphorin 6D
chr16_+_2033264 Show fit	0.05	ENST00000565855.5 ENST00000566198.1	SLC9A3R2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SLC9A3 regulator 2
chr12_-_52949818 Show fit	0.05	ENST00000546897.5 ENST00000552551.5	KRT8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin 8
chr14_-_74493322 Show fit	0.05	ENST00000553490.5 ENST00000557510.5	NPC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NPC intracellular cholesterol transporter 2
chr14_-_74493275 Show fit	0.05	ENST00000541064.5	NPC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NPC intracellular cholesterol transporter 2
chr14_-_74493291 Show fit	0.04	ENST00000238633.6 ENST00000555619.6 ENST00000434013.6	NPC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NPC intracellular cholesterol transporter 2
chr19_+_11089446 Show fit	0.04	ENST00000557933.5 ENST00000455727.6 ENST00000535915.5 ENST00000545707.5 ENST00000558518.6 ENST00000558013.5	LDLR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	low density lipoprotein receptor
chr12_-_91111460 Show fit	0.04	ENST00000266718.5	LUM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lumican
chr17_-_82098187 Show fit	0.04	ENST00000634990.1	FASN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid synthase
chr14_+_74493743 Show fit	0.04	ENST00000298818.12 ENST00000554924.1 ENST00000556816.6	ISCA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	iron-sulfur cluster assembly 2
chr15_-_82952683 Show fit	0.04	ENST00000450735.7 ENST00000304231.12	HOMER2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homer scaffold protein 2
chr10_-_50623897 Show fit	0.03	ENST00000361781.7 ENST00000429490.5 ENST00000619438.4	SGMS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sphingomyelin synthase 1
chrX_-_112840815 Show fit	0.03	ENST00000304758.5 ENST00000371959.9	AMOT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	angiomotin
chr15_-_72783685 Show fit	0.03	ENST00000456471.3 ENST00000311669.12	ADPGK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP dependent glucokinase
chr6_+_12012304 Show fit	0.03	ENST00000379388.7 ENST00000627968.2 ENST00000541134.5	HIVEP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HIVEP zinc finger 1
chr4_+_74365136 Show fit	0.03	ENST00000244869.3	EREG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	epiregulin
chr7_-_44541318 Show fit	0.03	ENST00000381160.8	NPC1L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NPC1 like intracellular cholesterol transporter 1
chr18_+_79395942 Show fit	0.03	ENST00000397790.6	NFATC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear factor of activated T cells 1
chr6_-_53348902 Show fit	0.03	ENST00000370913.5 ENST00000304434.11	ELOVL5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ELOVL fatty acid elongase 5
chr18_-_23586422 Show fit	0.03	ENST00000269228.10	NPC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NPC intracellular cholesterol transporter 1
chr19_+_55080363 Show fit	0.02	ENST00000588359.5 ENST00000245618.5	EPS8L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	EPS8 like 1
chr2_-_236503688 Show fit	0.02	ENST00000418802.2 ENST00000431676.6	IQCA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	IQ motif containing with AAA domain 1
chr15_+_67067780 Show fit	0.02	ENST00000679624.1	SMAD3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SMAD family member 3
chr15_-_72783611 Show fit	0.02	ENST00000563907.5	ADPGK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP dependent glucokinase
chr3_+_183253230 Show fit	0.02	ENST00000326505.4	B3GNT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr1_+_32753991 Show fit	0.02	ENST00000373481.7	KIAA1522 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KIAA1522
chr8_+_123416766 Show fit	0.02	ENST00000287387.7 ENST00000650311.1 ENST00000523356.1	NTAQ1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	N-terminal glutamine amidase 1
chr8_+_123416718 Show fit	0.02	ENST00000523984.5	NTAQ1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	N-terminal glutamine amidase 1
chr3_+_183253795 Show fit	0.02	ENST00000460419.1	B3GNT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr22_+_41833079 Show fit	0.02	ENST00000612482.4 ENST00000361204.9	SREBF2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sterol regulatory element binding transcription factor 2
chr3_+_160399630 Show fit	0.02	ENST00000465903.5 ENST00000485645.5 ENST00000472991.5 ENST00000467468.5 ENST00000469762.5 ENST00000357388.8 ENST00000489573.5 ENST00000462787.5 ENST00000490207.5 ENST00000485867.5	SMC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	structural maintenance of chromosomes 4
chr3_-_171810432 Show fit	0.02	ENST00000356327.9 ENST00000351298.9	PLD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phospholipase D1
chr17_-_29005913 Show fit	0.02	ENST00000442608.7 ENST00000317338.17 ENST00000335960.10	SEZ6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	seizure related 6 homolog
chr11_+_65712231 Show fit	0.02	ENST00000530446.5 ENST00000534104.5 ENST00000341318.9 ENST00000530605.5 ENST00000528198.5 ENST00000531880.1 ENST00000534650.5	KAT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine acetyltransferase 5
chr11_+_65711991 Show fit	0.02	ENST00000377046.7 ENST00000352980.8	KAT5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine acetyltransferase 5
chr5_+_160229499 Show fit	0.02	ENST00000402432.4	FABP6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid binding protein 6
chr6_+_78867524 Show fit	0.01	ENST00000369940.7	IRAK1BP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interleukin 1 receptor associated kinase 1 binding protein 1
chr19_-_55279690 Show fit	0.01	ENST00000587959.1 ENST00000585927.1 ENST00000587922.5 ENST00000585698.1	HSPBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HSPA (Hsp70) binding protein 1
chr5_-_150290093 Show fit	0.01	ENST00000672479.1	CAMK2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium/calmodulin dependent protein kinase II alpha
chr1_-_155262348 Show fit	0.01	ENST00000302631.8 ENST00000355379.3	SCAMP3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	secretory carrier membrane protein 3
chr6_+_41637005 Show fit	0.01	ENST00000419164.6 ENST00000373051.6	MDFI Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MyoD family inhibitor
chr14_+_32939243 Show fit	0.01	ENST00000346562.6 ENST00000548645.5 ENST00000356141.8 ENST00000357798.9	NPAS3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuronal PAS domain protein 3
chr11_+_22666604 Show fit	0.01	ENST00000454584.6	GAS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	growth arrest specific 2
chr17_-_41918944 Show fit	0.01	ENST00000352035.7 ENST00000590770.5 ENST00000590151.5	ACLY Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP citrate lyase
chr12_+_49295138 Show fit	0.01	ENST00000257860.9	PRPH Links Ensembl NCBI GeneCards UniProt NextProt Show fit	peripherin
chr17_-_75261586 Show fit	0.01	ENST00000580799.2 ENST00000538886.5 ENST00000537686.6	GGA3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr11_+_65615755 Show fit	0.01	ENST00000355703.4	PCNX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pecanex 3
chr5_-_39424966 Show fit	0.01	ENST00000515700.5 ENST00000320816.11 ENST00000339788.10	DAB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DAB adaptor protein 2
chr12_+_49950733 Show fit	0.01	ENST00000199280.4 ENST00000550862.1	AQP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	aquaporin 2
chr12_-_57846686 Show fit	0.01	ENST00000548823.1 ENST00000398073.7	CTDSP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CTD small phosphatase 2
chr8_+_123416735 Show fit	0.01	ENST00000524254.5	NTAQ1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	N-terminal glutamine amidase 1
chrX_+_27807990 Show fit	0.01	ENST00000356790.2	MAGEB10 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MAGE family member B10
chr15_+_78264552 Show fit	0.01	ENST00000394852.8 ENST00000343789.7	DNAJA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DnaJ heat shock protein family (Hsp40) member A4
chr9_+_128689201 Show fit	0.01	ENST00000322030.13	SET Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SET nuclear proto-oncogene
chr6_-_42746054 Show fit	0.01	ENST00000372876.2	TBCC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tubulin folding cofactor C
chr11_+_75240761 Show fit	0.01	ENST00000562197.3	TPBGL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	trophoblast glycoprotein like
chr16_+_66880503 Show fit	0.01	ENST00000568869.1 ENST00000311765.4 ENST00000561704.1 ENST00000568398.1 ENST00000566776.1	PDP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pyruvate dehyrogenase phosphatase catalytic subunit 2
chr7_-_44541262 Show fit	0.01	ENST00000289547.8 ENST00000546276.5 ENST00000423141.1	NPC1L1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NPC1 like intracellular cholesterol transporter 1
chr12_-_48004496 Show fit	0.01	ENST00000337299.7	COL2A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen type II alpha 1 chain
chr17_-_41918966 Show fit	0.00	ENST00000537919.5 ENST00000353196.5 ENST00000393896.6	ACLY Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ATP citrate lyase
chr22_+_23772839 Show fit	0.00	ENST00000215743.8	MMP11 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	matrix metallopeptidase 11
chr6_-_32184243 Show fit	0.00	ENST00000375055.6 ENST00000375076.9	AGER Links Ensembl NCBI GeneCards UniProt NextProt Show fit	advanced glycosylation end-product specific receptor
chr5_+_173989160 Show fit	0.00	ENST00000340147.7	C5orf47 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 5 open reading frame 47
chr10_-_73096850 Show fit	0.00	ENST00000307116.6 ENST00000373008.6 ENST00000394890.7	P4HA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolyl 4-hydroxylase subunit alpha 1
chr17_+_75261661 Show fit	0.00	ENST00000579761.5	MRPS7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S7
chr17_+_75261864 Show fit	0.00	ENST00000245539.11 ENST00000579002.5	MRPS7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mitochondrial ribosomal protein S7
chr10_-_73096974 Show fit	0.00	ENST00000440381.5 ENST00000263556.3	P4HA1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolyl 4-hydroxylase subunit alpha 1
chr5_-_139904460 Show fit	0.00	ENST00000340391.8	NRG2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuregulin 2
chr6_+_42173358 Show fit	0.00	ENST00000372958.2	GUCA1A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	guanylate cyclase activator 1A
chr1_+_32013848 Show fit	0.00	ENST00000327300.12 ENST00000492989.1	KHDRBS1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	KH RNA binding domain containing, signal transduction associated 1
chr6_-_32184287 Show fit	0.00	ENST00000375069.7 ENST00000375070.7 ENST00000438221.6 ENST00000620802.4 ENST00000538695.2	AGER Links Ensembl NCBI GeneCards UniProt NextProt Show fit	advanced glycosylation end-product specific receptor

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
0.0	0.1	GO:0019046	release from viral latency(GO:0019046)
0.0	0.2	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.1	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.0	0.0	GO:1905167	positive regulation of lysosomal protein catabolic process(GO:1905167)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:1990666	PCSK9-LDLR complex(GO:1990666)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	GO:0034189	very-low-density lipoprotein particle binding(GO:0034189)
0.0	0.0	GO:0047256	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0	0.0	GO:0016419	[acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)