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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TBX2

Z-value: 1.01

Motif logo

Transcription factors associated with TBX2

Gene Symbol Gene ID Gene Info
ENSG00000121068.14 T-box transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX2hg38_v1_chr17_+_61399835_613998510.482.2e-01Click!

Activity profile of TBX2 motif

Sorted Z-values of TBX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_12751789 1.32 ENST00000553030.6
bestrophin 2
chr1_+_78620432 1.31 ENST00000370751.10
ENST00000459784.6
ENST00000680110.1
ENST00000680295.1
interferon induced protein 44 like
chr13_+_101452569 1.21 ENST00000618057.4
integrin subunit beta like 1
chr5_+_111071710 1.17 ENST00000344895.4
thymic stromal lymphopoietin
chr1_+_78620722 1.01 ENST00000679848.1
interferon induced protein 44 like
chr2_+_120013068 1.01 ENST00000443902.6
ENST00000263713.10
erythrocyte membrane protein band 4.1 like 5
chr17_-_19745602 0.95 ENST00000444455.5
ENST00000439102.6
aldehyde dehydrogenase 3 family member A1
chr4_+_123396785 0.94 ENST00000505319.5
ENST00000651917.1
ENST00000610581.4
ENST00000339241.1
sprouty RTK signaling antagonist 1
chr6_+_123803853 0.90 ENST00000368417.6
sodium/potassium transporting ATPase interacting 2
chr9_+_87497222 0.81 ENST00000358077.9
death associated protein kinase 1
chr1_-_79006773 0.80 ENST00000671209.1
adhesion G protein-coupled receptor L4
chr9_-_76906041 0.79 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
prune homolog 2 with BCH domain
chr11_-_27722021 0.79 ENST00000314915.6
brain derived neurotrophic factor
chr3_-_112641128 0.78 ENST00000206423.8
coiled-coil domain containing 80
chr2_+_56183973 0.77 ENST00000407595.3
coiled-coil domain containing 85A
chr12_+_53050179 0.77 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
tensin 2
chr3_+_148730100 0.76 ENST00000474935.5
ENST00000475347.5
ENST00000461609.1
angiotensin II receptor type 1
chr1_-_79006680 0.71 ENST00000370742.4
ENST00000656841.1
adhesion G protein-coupled receptor L4
chr3_-_66500973 0.71 ENST00000383703.3
ENST00000273261.8
leucine rich repeats and immunoglobulin like domains 1
chr5_+_83471925 0.70 ENST00000502527.2
versican
chr12_+_65278643 0.70 ENST00000355192.8
ENST00000308259.10
ENST00000540804.5
ENST00000535664.5
ENST00000541189.5
methionine sulfoxide reductase B3
chr12_+_65279092 0.68 ENST00000646299.1
methionine sulfoxide reductase B3
chr22_+_30607145 0.67 ENST00000405742.7
transcobalamin 2
chr3_-_112641292 0.65 ENST00000439685.6
coiled-coil domain containing 80
chr22_+_30607167 0.64 ENST00000215838.8
transcobalamin 2
chr13_+_75804169 0.64 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr12_+_18242955 0.64 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr2_-_199457931 0.63 ENST00000417098.6
SATB homeobox 2
chr2_-_175005357 0.62 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr14_+_20999255 0.61 ENST00000554422.5
ENST00000298681.5
solute carrier family 39 member 2
chr12_+_65278919 0.60 ENST00000538045.5
ENST00000642411.1
ENST00000535239.5
ENST00000614640.4
methionine sulfoxide reductase B3
chr17_-_15263162 0.59 ENST00000674673.1
ENST00000675950.1
peripheral myelin protein 22
chr16_+_53099100 0.59 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr17_+_70169516 0.59 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr3_+_148739798 0.58 ENST00000402260.2
angiotensin II receptor type 1
chr12_+_65279445 0.58 ENST00000642404.1
methionine sulfoxide reductase B3
chr7_-_138701352 0.56 ENST00000421622.5
ENST00000674285.1
SVOP like
chr9_+_131502789 0.53 ENST00000372228.9
ENST00000341012.13
ENST00000677216.1
ENST00000676640.1
ENST00000441334.5
ENST00000402686.8
ENST00000677029.1
ENST00000676915.1
ENST00000676803.1
ENST00000677293.1
ENST00000678303.1
ENST00000677626.1
ENST00000372220.5
ENST00000683229.1
ENST00000418774.6
ENST00000430619.2
ENST00000448212.5
ENST00000679221.1
ENST00000678785.1
protein O-mannosyltransferase 1
chr7_+_48455063 0.53 ENST00000411975.5
ATP binding cassette subfamily A member 13
chr15_+_41621134 0.48 ENST00000566718.6
MAX dimerization protein MGA
chr10_+_52314272 0.46 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr19_+_35031263 0.46 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr9_-_20622479 0.44 ENST00000380338.9
MLLT3 super elongation complex subunit
chr2_-_79086847 0.44 ENST00000454188.5
regenerating family member 1 beta
chr2_+_157257687 0.43 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr15_+_41621492 0.43 ENST00000570161.6
MAX dimerization protein MGA
chr1_-_46132616 0.43 ENST00000423209.5
ENST00000262741.10
phosphoinositide-3-kinase regulatory subunit 3
chr1_-_46132650 0.43 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr9_+_121286586 0.43 ENST00000545652.6
gelsolin
chr4_-_165279679 0.42 ENST00000505354.2
glycerol kinase 3 pseudogene
chr8_-_27600000 0.42 ENST00000521770.1
clusterin
chr5_+_134525649 0.41 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr5_+_141192330 0.40 ENST00000239446.6
protocadherin beta 10
chr6_+_113857333 0.40 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr11_-_58844695 0.39 ENST00000287275.6
glycine-N-acyltransferase like 2
chr12_-_106987131 0.39 ENST00000240050.9
ENST00000392830.6
mitochondrial transcription termination factor 2
chr2_-_2326378 0.38 ENST00000647618.1
myelin transcription factor 1 like
chr15_+_92904447 0.37 ENST00000626782.2
chromodomain helicase DNA binding protein 2
chr12_-_89630552 0.36 ENST00000393164.6
ATPase plasma membrane Ca2+ transporting 1
chr13_+_23570370 0.36 ENST00000403372.6
ENST00000248484.9
TNF receptor superfamily member 19
chr1_-_150808251 0.36 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
cathepsin K
chr12_+_75481204 0.35 ENST00000550491.1
GLI pathogenesis related 1
chr12_-_90955172 0.35 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr2_-_177392673 0.35 ENST00000447413.1
ENST00000397057.6
ENST00000456746.5
ENST00000464747.5
novel transcript
nuclear factor, erythroid 2 like 2
chr11_-_615570 0.34 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr8_-_133571909 0.34 ENST00000521180.5
ENST00000517668.5
ENST00000399640.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr8_-_13514744 0.34 ENST00000316609.9
DLC1 Rho GTPase activating protein
chr6_+_159800249 0.32 ENST00000610273.5
ENST00000392167.4
PARN like, ribonuclease domain containing 1
chrX_+_51893533 0.32 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr12_-_106987068 0.32 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
mitochondrial transcription termination factor 2
chr2_+_188291854 0.32 ENST00000409830.6
GULP PTB domain containing engulfment adaptor 1
chr8_-_133571857 0.32 ENST00000522652.6
ENST00000648219.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr12_-_55728436 0.31 ENST00000552692.5
CD63 molecule
chr11_+_62611722 0.31 ENST00000525801.1
ENST00000534093.5
retinal outer segment membrane protein 1
chr1_+_61203496 0.31 ENST00000663597.1
nuclear factor I A
chr12_-_89708816 0.31 ENST00000428670.8
ATPase plasma membrane Ca2+ transporting 1
chrX_+_103607906 0.31 ENST00000243286.7
ENST00000372627.10
transcription elongation factor A like 3
chr15_-_89751292 0.30 ENST00000300057.4
mesoderm posterior bHLH transcription factor 1
chr6_+_83512501 0.30 ENST00000369700.4
serine protease 35
chr6_-_84227596 0.30 ENST00000257766.8
centrosomal protein 162
chr2_+_201129318 0.29 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr12_-_55727796 0.29 ENST00000550776.5
CD63 molecule
chr6_-_84227634 0.29 ENST00000617909.1
ENST00000403245.8
centrosomal protein 162
chr12_+_51424965 0.28 ENST00000514353.7
solute carrier family 4 member 8
chr5_+_141392616 0.28 ENST00000398604.3
protocadherin gamma subfamily A, 8
chr16_+_27402167 0.28 ENST00000564089.5
ENST00000337929.8
interleukin 21 receptor
chr2_-_165204042 0.27 ENST00000283254.12
ENST00000453007.1
sodium voltage-gated channel alpha subunit 3
chr21_-_30480364 0.27 ENST00000390689.3
keratin associated protein 19-1
chr2_-_40452046 0.27 ENST00000406785.6
solute carrier family 8 member A1
chr1_+_37556913 0.27 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr10_+_123008966 0.26 ENST00000368869.8
ENST00000358776.7
acyl-CoA dehydrogenase short/branched chain
chr2_-_119366682 0.26 ENST00000409877.5
ENST00000409523.1
ENST00000409466.6
chromosome 2 open reading frame 76
chr6_+_132552693 0.26 ENST00000275200.1
trace amine associated receptor 8
chr17_-_3063607 0.25 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr1_-_28643005 0.25 ENST00000263974.4
ENST00000373824.9
ENST00000495422.2
TATA-box binding protein associated factor 12
chr2_-_61018228 0.25 ENST00000316752.11
pseudouridine synthase 10
chr19_-_46023046 0.25 ENST00000008938.5
peptidoglycan recognition protein 1
chr17_+_60677822 0.25 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chr12_-_55727828 0.25 ENST00000546939.5
CD63 molecule
chr15_-_55289756 0.25 ENST00000336787.6
RAB27A, member RAS oncogene family
chr19_-_50025936 0.25 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr8_+_22565236 0.25 ENST00000523900.5
sorbin and SH3 domain containing 3
chr17_-_8163522 0.25 ENST00000404970.3
vesicle associated membrane protein 2
chr3_-_49429252 0.25 ENST00000615713.4
nicolin 1
chr5_-_131797030 0.24 ENST00000615660.4
folliculin interacting protein 1
chr12_-_55728640 0.24 ENST00000551173.5
ENST00000420846.7
CD63 molecule
chr5_-_160852200 0.24 ENST00000327245.10
ATPase phospholipid transporting 10B (putative)
chr14_+_94612383 0.24 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr2_-_119366807 0.24 ENST00000334816.12
chromosome 2 open reading frame 76
chr6_+_131573219 0.23 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr19_-_45478817 0.23 ENST00000423698.6
ERCC excision repair 1, endonuclease non-catalytic subunit
chr2_+_177392734 0.23 ENST00000680770.1
ENST00000637633.2
ENST00000679459.1
ENST00000409888.1
ENST00000264167.11
ENST00000642466.2
alkylglycerone phosphate synthase
chr10_+_13100075 0.23 ENST00000378747.8
ENST00000378757.6
ENST00000378752.7
ENST00000378748.7
optineurin
chr14_-_69153106 0.23 ENST00000341516.10
DDB1 and CUL4 associated factor 5
chr3_-_49429304 0.23 ENST00000636166.1
ENST00000273598.8
ENST00000436744.2
novel protein
nicolin 1
chr5_-_131796921 0.23 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr11_+_61680373 0.23 ENST00000257215.10
diacylglycerol lipase alpha
chr4_-_128288791 0.23 ENST00000613358.4
ENST00000520121.6
progesterone receptor membrane component 2
chr3_+_119468952 0.23 ENST00000476573.5
ENST00000295588.9
protein O-glucosyltransferase 1
chrX_-_57910458 0.23 ENST00000358697.6
zinc finger X-linked duplicated A
chr19_-_6670151 0.22 ENST00000675206.1
TNF superfamily member 14
chr5_+_102755269 0.22 ENST00000304400.12
ENST00000455264.7
ENST00000684529.1
ENST00000438793.8
ENST00000682882.1
ENST00000682972.1
ENST00000348126.7
ENST00000512073.1
peptidylglycine alpha-amidating monooxygenase
chr22_+_40045451 0.22 ENST00000402203.5
trinucleotide repeat containing adaptor 6B
chr19_-_44448435 0.22 ENST00000588655.1
ENST00000592308.1
ENST00000614049.5
ENST00000613197.4
novel transcript
zinc finger protein 229
chr1_-_1074303 0.21 ENST00000453464.3
ring finger protein 223
chr5_+_140107777 0.21 ENST00000505703.2
ENST00000651386.1
purine rich element binding protein A
chr12_+_26052563 0.21 ENST00000537946.5
ENST00000541218.5
ENST00000282884.13
ENST00000545413.1
Ras association domain family member 8
chr13_+_30713477 0.21 ENST00000617770.4
arachidonate 5-lipoxygenase activating protein
chr7_+_35800932 0.21 ENST00000635172.1
ENST00000399034.7
ENST00000350320.10
ENST00000435235.6
ENST00000672279.1
ENST00000634600.1
ENST00000635047.1
septin 7
chr10_+_44911316 0.21 ENST00000544540.5
ENST00000389583.5
transmembrane protein 72
chr19_-_6670117 0.21 ENST00000245912.7
TNF superfamily member 14
chr19_-_18255385 0.21 ENST00000355502.7
ENST00000643046.1
novel protein
novel protein
chr12_-_55728339 0.21 ENST00000552754.5
CD63 molecule
chr12_+_57460127 0.21 ENST00000532291.5
ENST00000543426.5
ENST00000546141.5
GLI family zinc finger 1
chr9_+_122510802 0.21 ENST00000335302.5
olfactory receptor family 1 subfamily J member 2
chr16_+_14945885 0.21 ENST00000537062.1
nuclear pore complex interacting protein family member A1
chr11_-_26572130 0.21 ENST00000527569.1
mucin 15, cell surface associated
chr2_+_85354720 0.20 ENST00000409331.6
ENST00000409344.7
ENST00000393852.8
ENST00000409013.8
ENST00000315658.11
ENST00000462891.7
ELMO domain containing 3
chr12_+_56266934 0.20 ENST00000308197.10
coenzyme Q10A
chr6_+_45422485 0.20 ENST00000359524.7
RUNX family transcription factor 2
chrX_-_19670983 0.20 ENST00000379716.5
SH3 domain containing kinase binding protein 1
chr9_+_2157647 0.20 ENST00000452193.5
ENST00000324954.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_53945567 0.20 ENST00000371378.6
heat shock protein family B (small) member 11
chr12_+_56267249 0.20 ENST00000433805.6
coenzyme Q10A
chr12_-_55728977 0.19 ENST00000552164.5
CD63 molecule
chr9_+_33750669 0.19 ENST00000361005.10
ENST00000342836.9
ENST00000429677.8
serine protease 3
chr1_-_150629470 0.19 ENST00000638926.1
ENST00000503241.1
ENST00000369016.8
ENST00000339643.9
ENST00000271690.12
ENST00000356527.9
ENST00000362052.7
ENST00000503345.1
ENST00000369014.10
endosulfine alpha
chr17_-_15262537 0.19 ENST00000395936.7
ENST00000675819.1
ENST00000674707.1
ENST00000675854.1
ENST00000426385.4
ENST00000395938.7
ENST00000612492.5
ENST00000675808.1
peripheral myelin protein 22
chr12_-_55727044 0.19 ENST00000548160.5
CD63 molecule
chr15_-_43266857 0.19 ENST00000349114.8
ENST00000220420.10
transglutaminase 5
chr10_+_68560317 0.19 ENST00000373644.5
tet methylcytosine dioxygenase 1
chr5_-_55994945 0.19 ENST00000381298.7
ENST00000502326.7
interleukin 6 signal transducer
chr1_-_150010675 0.19 ENST00000417191.2
ENST00000581312.6
OTU deubiquitinase 7B
chr9_-_130043154 0.19 ENST00000355681.3
ENST00000446176.7
ENST00000443566.6
ENST00000420781.5
formin binding protein 1
chr11_-_114400417 0.19 ENST00000325636.8
ENST00000623205.2
chromosome 11 open reading frame 71
chr19_+_51693327 0.19 ENST00000637797.2
sperm acrosome associated 6
chr2_-_119366757 0.19 ENST00000414534.1
chromosome 2 open reading frame 76
chr14_-_94517844 0.18 ENST00000341228.2
serpin family A member 12
chr10_-_70132801 0.18 ENST00000307864.3
ENST00000613322.4
apoptosis inducing factor mitochondria associated 2
chrX_+_18425597 0.18 ENST00000623535.2
ENST00000674046.1
cyclin dependent kinase like 5
chr2_+_201129483 0.18 ENST00000440180.5
CASP8 and FADD like apoptosis regulator
chr11_-_615921 0.18 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
interferon regulatory factor 7
chr16_-_30893990 0.18 ENST00000215115.5
BAF chromatin remodeling complex subunit BCL7C
chr10_+_7818497 0.18 ENST00000344293.6
TATA-box binding protein associated factor 3
chr20_+_44966478 0.17 ENST00000499879.6
ENST00000372806.8
ENST00000372801.5
serine/threonine kinase 4
chr12_-_55728994 0.17 ENST00000257857.9
CD63 molecule
chr1_-_145927447 0.17 ENST00000632555.1
ENST00000369307.4
ENST00000583313.7
RNA binding motif protein 8A
chr16_-_30893942 0.17 ENST00000572628.5
BAF chromatin remodeling complex subunit BCL7C
chr12_-_55727080 0.17 ENST00000548898.5
ENST00000552067.5
CD63 molecule
chr15_+_41332862 0.17 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr6_-_89352706 0.17 ENST00000435041.3
ubiquitin conjugating enzyme E2 J1
chr5_-_131796965 0.17 ENST00000514667.1
ENST00000511848.1
ENST00000510461.6
novel protein
folliculin interacting protein 1
chr1_-_53945584 0.17 ENST00000371377.3
heat shock protein family B (small) member 11
chr9_+_17135017 0.16 ENST00000380641.4
ENST00000380647.8
centlein
chr19_+_54769808 0.16 ENST00000291633.7
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
chr1_-_34929574 0.16 ENST00000373347.6
DLG associated protein 3
chr1_+_203475798 0.16 ENST00000343110.3
proline and arginine rich end leucine rich repeat protein
chr10_-_22714531 0.16 ENST00000376573.9
phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
chr2_+_119366924 0.16 ENST00000535757.5
ENST00000535617.5
ENST00000627093.2
ENST00000355857.8
ENST00000409094.5
ENST00000542275.5
ENST00000311521.8
diazepam binding inhibitor, acyl-CoA binding protein
chrX_+_65588368 0.16 ENST00000609672.5
moesin
chr6_-_24935942 0.16 ENST00000645100.1
ENST00000643898.2
ENST00000613507.4
RHO family interacting cell polarization regulator 2
chr8_-_19602484 0.16 ENST00000454498.6
ENST00000520003.5
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chrX_-_53434341 0.16 ENST00000375298.4
ENST00000375304.9
ENST00000684692.1
ENST00000168216.11
hydroxysteroid 17-beta dehydrogenase 10
chr4_-_139084289 0.15 ENST00000510408.5
ENST00000379549.7
ENST00000358635.7
E74 like ETS transcription factor 2
chr11_-_7941708 0.15 ENST00000642047.1
olfactory receptor family 10 subfamily A member 3
chr7_+_17299234 0.15 ENST00000637807.1
novel protein
chr7_+_116525524 0.15 ENST00000405348.6
caveolin 1
chr2_-_168913277 0.15 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr6_-_30617232 0.15 ENST00000376511.7
protein phosphatase 1 regulatory subunit 10
chr19_+_7678501 0.15 ENST00000597959.1
novel protein
chr11_+_73647549 0.15 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr19_+_54769785 0.15 ENST00000336077.11
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1
chr5_-_69332723 0.15 ENST00000511257.1
ENST00000396496.7
ENST00000383374.6
coiled-coil domain containing 125
chr21_-_30497160 0.15 ENST00000334058.3
keratin associated protein 19-4
chr19_+_36916298 0.15 ENST00000427117.5
ENST00000333987.12
ENST00000587130.5
ENST00000415168.5
ENST00000444991.5
zinc finger protein 568
chr22_-_24555920 0.14 ENST00000621833.4
ENST00000404664.7
guanylyl cyclase domain containing 1
chr2_+_218382265 0.14 ENST00000233202.11
solute carrier family 11 member 1
chr1_+_244835616 0.14 ENST00000366528.3
ENST00000411948.7
cytochrome c oxidase assembly factor COX20
chr5_-_178590367 0.14 ENST00000390654.8
collagen type XXIII alpha 1 chain
chr1_+_109539865 0.14 ENST00000618721.4
ENST00000527748.5
ENST00000616874.1
G protein-coupled receptor 61

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.3 1.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.3 0.8 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.2 0.9 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 0.7 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.2 2.6 GO:0030091 protein repair(GO:0030091)
0.2 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 0.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 0.5 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of mesodermal cell fate specification(GO:0042662) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 2.0 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.6 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 1.3 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.3 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.1 0.3 GO:0060032 notochord regression(GO:0060032)
0.1 0.4 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.3 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 0.5 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.4 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.3 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.1 0.7 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 0.5 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.5 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.2 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.1 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.2 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.4 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.5 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.3 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.2 GO:0043320 natural killer cell degranulation(GO:0043320) regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.8 GO:0032060 bleb assembly(GO:0032060)
0.0 0.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0042231 interleukin-13 biosynthetic process(GO:0042231) positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.8 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.9 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0051586 peptidyl-cysteine methylation(GO:0018125) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.1 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.3 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.6 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.0 GO:2000157 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.0 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0097646 positive regulation of protein kinase A signaling(GO:0010739) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.6 GO:0005879 axonemal microtubule(GO:0005879)
0.1 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.4 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0097545 axonemal outer doublet(GO:0097545)
0.0 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.5 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.8 GO:0043218 compact myelin(GO:0043218)
0.0 0.3 GO:0033276 SAGA complex(GO:0000124) transcription factor TFTC complex(GO:0033276)
0.0 1.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.1 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.0 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.3 2.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 0.8 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.2 1.0 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.3 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.4 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0004923 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 1.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0047238 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237) glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.9 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation