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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TBX21_TBR1

Z-value: 0.61

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Transcription factors associated with TBX21_TBR1

Gene Symbol Gene ID Gene Info
ENSG00000073861.3 T-box transcription factor 21
ENSG00000136535.15 T-box brain transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX21hg38_v1_chr17_+_47733228_477332420.639.1e-02Click!
TBR1hg38_v1_chr2_+_161416273_161416325-0.285.0e-01Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_12751789 1.30 ENST00000553030.6
bestrophin 2
chr4_+_123396785 1.04 ENST00000505319.5
ENST00000651917.1
ENST00000610581.4
ENST00000339241.1
sprouty RTK signaling antagonist 1
chr6_+_123803853 1.01 ENST00000368417.6
sodium/potassium transporting ATPase interacting 2
chr19_+_12751672 0.97 ENST00000549706.5
bestrophin 2
chr3_-_100993409 0.92 ENST00000471714.6
ABI family member 3 binding protein
chr3_-_100993507 0.92 ENST00000284322.10
ABI family member 3 binding protein
chr9_-_76906041 0.90 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
prune homolog 2 with BCH domain
chr1_+_78620432 0.79 ENST00000370751.10
ENST00000459784.6
ENST00000680110.1
ENST00000680295.1
interferon induced protein 44 like
chr1_+_78620722 0.70 ENST00000679848.1
interferon induced protein 44 like
chr11_-_27722021 0.65 ENST00000314915.6
brain derived neurotrophic factor
chr12_-_91182652 0.56 ENST00000552145.5
ENST00000546745.5
decorin
chr14_+_94612383 0.54 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr12_-_91182784 0.52 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chr2_-_199457931 0.52 ENST00000417098.6
SATB homeobox 2
chr12_-_95790755 0.52 ENST00000343702.9
ENST00000344911.8
netrin 4
chr3_-_66500973 0.51 ENST00000383703.3
ENST00000273261.8
leucine rich repeats and immunoglobulin like domains 1
chr2_-_175005357 0.46 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr5_+_111071710 0.45 ENST00000344895.4
thymic stromal lymphopoietin
chr1_+_37556913 0.44 ENST00000296218.8
ENST00000652629.1
dynein axonemal light intermediate chain 1
chr5_+_141192330 0.41 ENST00000239446.6
protocadherin beta 10
chr22_+_30607145 0.41 ENST00000405742.7
transcobalamin 2
chr12_-_89630552 0.40 ENST00000393164.6
ATPase plasma membrane Ca2+ transporting 1
chr15_+_41621134 0.40 ENST00000566718.6
MAX dimerization protein MGA
chr22_+_30607167 0.39 ENST00000215838.8
transcobalamin 2
chr6_-_46491956 0.39 ENST00000306764.11
regulator of calcineurin 2
chr16_+_53099100 0.38 ENST00000565832.5
chromodomain helicase DNA binding protein 9
chr1_-_163202835 0.38 ENST00000527988.1
ENST00000531476.1
ENST00000530507.5
ENST00000313961.10
regulator of G protein signaling 5
chr13_+_75804169 0.37 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr22_+_30607203 0.36 ENST00000407817.3
transcobalamin 2
chr15_+_41621492 0.36 ENST00000570161.6
MAX dimerization protein MGA
chr5_-_147906530 0.35 ENST00000318315.5
ENST00000515291.1
chromosome 5 open reading frame 46
chr12_+_65278643 0.35 ENST00000355192.8
ENST00000308259.10
ENST00000540804.5
ENST00000535664.5
ENST00000541189.5
methionine sulfoxide reductase B3
chr12_+_65279092 0.35 ENST00000646299.1
methionine sulfoxide reductase B3
chr9_+_87497222 0.34 ENST00000358077.9
death associated protein kinase 1
chr9_+_131502789 0.32 ENST00000372228.9
ENST00000341012.13
ENST00000677216.1
ENST00000676640.1
ENST00000441334.5
ENST00000402686.8
ENST00000677029.1
ENST00000676915.1
ENST00000676803.1
ENST00000677293.1
ENST00000678303.1
ENST00000677626.1
ENST00000372220.5
ENST00000683229.1
ENST00000418774.6
ENST00000430619.2
ENST00000448212.5
ENST00000679221.1
ENST00000678785.1
protein O-mannosyltransferase 1
chr5_+_134525649 0.31 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr11_-_83071819 0.31 ENST00000524635.1
ENST00000526205.5
ENST00000533486.5
ENST00000533276.6
ENST00000527633.6
RAB30, member RAS oncogene family
chr13_+_75804221 0.31 ENST00000489941.6
ENST00000525373.5
LIM domain 7
chr12_+_65278919 0.30 ENST00000538045.5
ENST00000642411.1
ENST00000535239.5
ENST00000614640.4
methionine sulfoxide reductase B3
chr15_-_89751292 0.29 ENST00000300057.4
mesoderm posterior bHLH transcription factor 1
chr2_-_2326378 0.28 ENST00000647618.1
myelin transcription factor 1 like
chrX_+_51893533 0.27 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr17_-_15263162 0.27 ENST00000674673.1
ENST00000675950.1
peripheral myelin protein 22
chr11_+_61680373 0.27 ENST00000257215.10
diacylglycerol lipase alpha
chr15_-_82647503 0.26 ENST00000567678.1
ENST00000620182.4
cytoplasmic polyadenylation element binding protein 1
chr2_+_157257687 0.25 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr15_-_82647336 0.25 ENST00000617522.4
ENST00000684509.1
cytoplasmic polyadenylation element binding protein 1
chr6_-_167157980 0.25 ENST00000366834.2
G protein-coupled receptor 31
chr1_-_46132650 0.25 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr1_-_46132616 0.25 ENST00000423209.5
ENST00000262741.10
phosphoinositide-3-kinase regulatory subunit 3
chr2_-_79086847 0.24 ENST00000454188.5
regenerating family member 1 beta
chr12_-_90955172 0.24 ENST00000358859.3
coiled-coil glutamate rich protein 1
chr18_+_6729698 0.23 ENST00000383472.9
Rho GTPase activating protein 28
chr2_-_156332694 0.23 ENST00000424077.1
ENST00000426264.5
ENST00000421709.1
ENST00000339562.9
nuclear receptor subfamily 4 group A member 2
chr6_-_153131221 0.23 ENST00000206262.2
regulator of G protein signaling 17
chr11_+_73647549 0.22 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr12_+_65279445 0.22 ENST00000642404.1
methionine sulfoxide reductase B3
chr5_+_102754631 0.22 ENST00000510208.2
peptidylglycine alpha-amidating monooxygenase
chr11_-_83071917 0.22 ENST00000534141.5
RAB30, member RAS oncogene family
chr1_+_25819926 0.22 ENST00000533762.5
ENST00000529116.5
ENST00000474295.5
ENST00000488327.6
ENST00000472643.5
ENST00000374303.7
ENST00000526894.5
ENST00000524618.5
ENST00000374307.9
mitochondrial fission regulator 1 like
chr7_+_27242796 0.21 ENST00000496902.7
even-skipped homeobox 1
chr1_+_25820146 0.21 ENST00000525713.5
ENST00000374301.7
mitochondrial fission regulator 1 like
chr5_-_131797030 0.21 ENST00000615660.4
folliculin interacting protein 1
chr5_-_131796921 0.21 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr11_-_114400417 0.20 ENST00000325636.8
ENST00000623205.2
chromosome 11 open reading frame 71
chr14_+_20999255 0.20 ENST00000554422.5
ENST00000298681.5
solute carrier family 39 member 2
chr3_-_187745460 0.19 ENST00000406870.7
BCL6 transcription repressor
chr2_-_177392673 0.19 ENST00000447413.1
ENST00000397057.6
ENST00000456746.5
ENST00000464747.5
novel transcript
nuclear factor, erythroid 2 like 2
chr7_-_138701352 0.19 ENST00000421622.5
ENST00000674285.1
SVOP like
chr4_+_159267737 0.18 ENST00000264431.8
Rap guanine nucleotide exchange factor 2
chr17_-_8163522 0.18 ENST00000404970.3
vesicle associated membrane protein 2
chr8_-_27600000 0.18 ENST00000521770.1
clusterin
chr4_+_26584064 0.18 ENST00000264866.9
ENST00000505206.5
ENST00000511789.5
TBC1 domain family member 19
chr15_+_60004305 0.18 ENST00000396057.6
forkhead box B1
chr5_+_141370236 0.17 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr6_+_131573219 0.17 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr8_+_38728550 0.17 ENST00000520340.5
ENST00000518415.5
transforming acidic coiled-coil containing protein 1
chr15_+_43826961 0.17 ENST00000381246.6
ENST00000452115.1
ENST00000263795.11
WD repeat domain 76
chr12_+_18242955 0.17 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr19_-_35745391 0.17 ENST00000378975.8
ENST00000587886.2
ENST00000412391.6
ENST00000292879.9
U2 small nuclear RNA auxiliary factor 1 like 4
chr1_+_50970234 0.16 ENST00000371761.4
cyclin dependent kinase inhibitor 2C
chr4_-_8071978 0.16 ENST00000514025.5
actin binding LIM protein family member 2
chr4_-_185810894 0.16 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chr10_+_92691897 0.16 ENST00000492654.3
hematopoietically expressed homeobox
chr9_-_35815034 0.16 ENST00000259667.6
histidine triad nucleotide binding protein 2
chr17_+_60677822 0.16 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3 microtubule associated cell migration factor
chrX_+_103607906 0.15 ENST00000243286.7
ENST00000372627.10
transcription elongation factor A like 3
chr1_-_37034492 0.15 ENST00000373091.8
glutamate ionotropic receptor kainate type subunit 3
chr20_+_36092698 0.15 ENST00000430276.5
ENST00000373950.6
ENST00000373946.7
ENST00000441639.5
ENST00000628415.2
ENST00000452261.5
erythrocyte membrane protein band 4.1 like 1
chr6_+_39792298 0.15 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr9_+_17135017 0.15 ENST00000380641.4
ENST00000380647.8
centlein
chr3_-_61251376 0.15 ENST00000476844.5
ENST00000488467.5
ENST00000492590.6
ENST00000468189.5
fragile histidine triad diadenosine triphosphatase
chr2_-_61018228 0.15 ENST00000316752.11
pseudouridine synthase 10
chr12_+_130953898 0.15 ENST00000261654.10
adhesion G protein-coupled receptor D1
chr17_-_28335421 0.14 ENST00000578122.5
ENST00000579419.5
ENST00000585313.5
ENST00000578985.5
ENST00000577498.1
ENST00000585089.5
ENST00000357896.7
ENST00000395418.8
ENST00000588477.5
intraflagellar transport 20
chr2_+_161231078 0.14 ENST00000439442.1
TRAF family member associated NFKB activator
chr1_-_145927447 0.14 ENST00000632555.1
ENST00000369307.4
ENST00000583313.7
RNA binding motif protein 8A
chr6_+_45422485 0.14 ENST00000359524.7
RUNX family transcription factor 2
chr3_-_49429252 0.14 ENST00000615713.4
nicolin 1
chr20_+_18145083 0.14 ENST00000489634.2
lysine acetyltransferase 14
chr19_+_45864318 0.14 ENST00000302177.3
forkhead box A3
chr11_+_134069060 0.14 ENST00000534549.5
ENST00000441717.3
ENST00000299106.9
junctional adhesion molecule 3
chr16_+_69106219 0.14 ENST00000219322.7
hyaluronan synthase 3
chr1_-_1074303 0.14 ENST00000453464.3
ring finger protein 223
chrX_+_16650155 0.13 ENST00000380200.3
S100 calcium binding protein G
chr19_-_50025936 0.13 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr21_-_30497160 0.13 ENST00000334058.3
keratin associated protein 19-4
chrX_-_70289888 0.13 ENST00000239666.9
ENST00000374454.1
PDZ domain containing 11
chr6_-_84227596 0.13 ENST00000257766.8
centrosomal protein 162
chrX_+_110002635 0.13 ENST00000372072.7
transmembrane protein 164
chr3_-_49429304 0.13 ENST00000636166.1
ENST00000273598.8
ENST00000436744.2
novel protein
nicolin 1
chr8_+_22570944 0.13 ENST00000517962.1
sorbin and SH3 domain containing 3
chr6_-_84227634 0.12 ENST00000617909.1
ENST00000403245.8
centrosomal protein 162
chr5_-_131796965 0.12 ENST00000514667.1
ENST00000511848.1
ENST00000510461.6
novel protein
folliculin interacting protein 1
chr9_+_121286586 0.12 ENST00000545652.6
gelsolin
chr1_-_120176450 0.12 ENST00000578049.4
SEC22 homolog B, vesicle trafficking protein
chr8_-_92095215 0.12 ENST00000360348.6
ENST00000520428.5
ENST00000518992.5
ENST00000520556.5
ENST00000518317.5
ENST00000521319.5
ENST00000521375.5
ENST00000518449.5
ENST00000613886.4
RUNX1 partner transcriptional co-repressor 1
chr8_-_42768602 0.12 ENST00000534622.5
cholinergic receptor nicotinic alpha 6 subunit
chr2_+_209771814 0.12 ENST00000673951.1
ENST00000673920.1
unc-80 homolog, NALCN channel complex subunit
chr9_+_122510802 0.12 ENST00000335302.5
olfactory receptor family 1 subfamily J member 2
chr1_+_69567906 0.12 ENST00000651989.2
leucine rich repeat containing 7
chr5_+_55024250 0.12 ENST00000231009.3
granzyme K
chr12_+_57460127 0.12 ENST00000532291.5
ENST00000543426.5
ENST00000546141.5
GLI family zinc finger 1
chr6_+_159800249 0.12 ENST00000610273.5
ENST00000392167.4
PARN like, ribonuclease domain containing 1
chr11_+_45885625 0.11 ENST00000241014.6
mitogen-activated protein kinase 8 interacting protein 1
chr2_+_201129318 0.11 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr16_-_79599902 0.11 ENST00000569649.1
MAF bZIP transcription factor
chr7_+_44748547 0.11 ENST00000413916.5
zinc finger MIZ-type containing 2
chr8_-_42768781 0.11 ENST00000276410.7
cholinergic receptor nicotinic alpha 6 subunit
chr12_-_55727044 0.11 ENST00000548160.5
CD63 molecule
chr12_+_75481204 0.11 ENST00000550491.1
GLI pathogenesis related 1
chr11_+_6481473 0.11 ENST00000530751.1
ENST00000254616.11
translocase of inner mitochondrial membrane 10B
chr17_+_6756035 0.11 ENST00000361842.8
ENST00000574907.5
XIAP associated factor 1
chr2_+_74549026 0.10 ENST00000409429.5
docking protein 1
chr1_+_212950634 0.10 ENST00000366965.6
ENST00000366967.6
vasohibin 2
chr1_-_112704921 0.10 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr13_+_53028806 0.10 ENST00000219022.3
olfactomedin 4
chr12_-_68933161 0.10 ENST00000549781.1
ENST00000551568.6
ENST00000548262.5
carboxypeptidase M
chr5_+_95391361 0.10 ENST00000283357.10
family with sequence similarity 81 member B
chr12_+_12785652 0.10 ENST00000356591.5
apolipoprotein L domain containing 1
chr6_+_132552693 0.10 ENST00000275200.1
trace amine associated receptor 8
chr12_-_76486061 0.10 ENST00000548341.5
oxysterol binding protein like 8
chr11_-_33892010 0.10 ENST00000257818.3
LIM domain only 2
chr5_+_138084015 0.10 ENST00000504809.5
ENST00000506684.6
ENST00000398754.1
Wnt family member 8A
chr13_+_30713477 0.10 ENST00000617770.4
arachidonate 5-lipoxygenase activating protein
chr17_-_3063607 0.10 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr17_-_8376658 0.10 ENST00000643221.1
ENST00000647210.1
ENST00000649935.1
ENST00000396267.3
KRAB-A domain containing 2
chr22_+_40045451 0.10 ENST00000402203.5
trinucleotide repeat containing adaptor 6B
chr2_+_203328378 0.10 ENST00000430418.5
ENST00000261018.12
ENST00000295851.10
ENST00000424558.5
ENST00000417864.5
ENST00000422511.6
abl interactor 2
chr8_+_38728186 0.10 ENST00000519416.5
ENST00000520615.5
transforming acidic coiled-coil containing protein 1
chr17_+_44847874 0.10 ENST00000253410.3
HIG1 hypoxia inducible domain family member 1B
chr9_-_35684766 0.10 ENST00000644325.1
tropomyosin 2
chr2_+_218382265 0.10 ENST00000233202.11
solute carrier family 11 member 1
chr16_+_27402167 0.10 ENST00000564089.5
ENST00000337929.8
interleukin 21 receptor
chr2_+_209771972 0.10 ENST00000439458.5
ENST00000272845.10
unc-80 homolog, NALCN channel complex subunit
chr17_-_58531941 0.09 ENST00000581607.1
ENST00000317256.10
ENST00000426861.5
ENST00000580809.5
ENST00000577729.5
ENST00000583291.1
septin 4
chr17_+_9162935 0.09 ENST00000436734.1
netrin 1
chr1_-_28643005 0.09 ENST00000263974.4
ENST00000373824.9
ENST00000495422.2
TATA-box binding protein associated factor 12
chr4_-_128288791 0.09 ENST00000613358.4
ENST00000520121.6
progesterone receptor membrane component 2
chr10_+_92691813 0.09 ENST00000472590.6
hematopoietically expressed homeobox
chr12_-_55727080 0.09 ENST00000548898.5
ENST00000552067.5
CD63 molecule
chrX_-_15854791 0.09 ENST00000545766.7
ENST00000380291.5
ENST00000672987.1
ENST00000329235.6
adaptor related protein complex 1 subunit sigma 2
chr16_-_18926408 0.09 ENST00000446231.7
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr10_-_63269057 0.09 ENST00000542921.5
jumonji domain containing 1C
chr1_-_241640347 0.09 ENST00000366554.3
ENST00000366553.3
opsin 3
CHM like Rab escort protein
chr5_+_140107777 0.09 ENST00000505703.2
ENST00000651386.1
purine rich element binding protein A
chrX_-_141176999 0.09 ENST00000370526.5
LDOC1 regulator of NFKB signaling
chr5_+_6448832 0.09 ENST00000399816.4
ubiquitin conjugating enzyme E2 Q family like 1
chr22_-_42646960 0.09 ENST00000402438.5
ENST00000407623.7
ENST00000438270.1
cytochrome b5 reductase 3
chr6_-_33711684 0.09 ENST00000374231.8
ENST00000607484.6
ubiquinol-cytochrome c reductase complex assembly factor 2
chr19_-_38899529 0.09 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr2_+_227813834 0.09 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr5_-_177006350 0.09 ENST00000377227.8
ubiquitin interaction motif containing 1
chr17_-_78360066 0.09 ENST00000587578.1
ENST00000330871.3
suppressor of cytokine signaling 3
chrX_+_18425597 0.09 ENST00000623535.2
ENST00000674046.1
cyclin dependent kinase like 5
chr8_-_22232020 0.09 ENST00000454243.7
ENST00000321613.7
phytanoyl-CoA 2-hydroxylase interacting protein
chr17_-_15262537 0.08 ENST00000395936.7
ENST00000675819.1
ENST00000674707.1
ENST00000675854.1
ENST00000426385.4
ENST00000395938.7
ENST00000612492.5
ENST00000675808.1
peripheral myelin protein 22
chr19_-_51372640 0.08 ENST00000600427.5
ENST00000221978.10
natural killer cell granule protein 7
chr16_+_21704963 0.08 ENST00000388957.3
otoancorin
chr10_+_123008966 0.08 ENST00000368869.8
ENST00000358776.7
acyl-CoA dehydrogenase short/branched chain
chr1_-_53945567 0.08 ENST00000371378.6
heat shock protein family B (small) member 11
chr19_+_49877694 0.08 ENST00000221543.10
TBC1 domain family member 17
chr19_-_46023046 0.08 ENST00000008938.5
peptidoglycan recognition protein 1
chr6_+_391743 0.08 ENST00000380956.9
interferon regulatory factor 4
chr11_+_66510626 0.08 ENST00000526815.5
ENST00000318312.12
ENST00000525809.5
ENST00000455748.6
ENST00000393994.4
ENST00000630659.2
Bardet-Biedl syndrome 1
chr11_-_1762403 0.08 ENST00000367196.4
cathepsin D
chr1_+_26787926 0.08 ENST00000674202.1
ENST00000674222.1
phosphatidylinositol glycan anchor biosynthesis class V
chr12_-_106987068 0.08 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
mitochondrial transcription termination factor 2
chr2_+_177392734 0.08 ENST00000680770.1
ENST00000637633.2
ENST00000679459.1
ENST00000409888.1
ENST00000264167.11
ENST00000642466.2
alkylglycerone phosphate synthase
chr17_-_11997372 0.08 ENST00000322748.7
ENST00000454073.7
ENST00000580306.7
ENST00000580903.1
zinc finger protein 18
chr8_+_78666056 0.08 ENST00000263849.9
zinc finger C2HC-type containing 1A
chr9_-_111794926 0.08 ENST00000682961.1
ENST00000374283.5
shortage in chiasmata 1
chr9_+_34329495 0.08 ENST00000346365.8
ENST00000379155.9
ENST00000618590.1
nudix hydrolase 2
chr9_+_34329545 0.08 ENST00000379158.7
nudix hydrolase 2
chr9_-_130043154 0.08 ENST00000355681.3
ENST00000446176.7
ENST00000443566.6
ENST00000420781.5
formin binding protein 1
chr6_-_30617232 0.08 ENST00000376511.7
protein phosphatase 1 regulatory subunit 10
chr22_-_17221841 0.07 ENST00000449907.7
ENST00000441548.1
ENST00000399839.5
adenosine deaminase 2
chr16_-_1379674 0.07 ENST00000402641.6
ENST00000248104.11
ENST00000674376.1
ENST00000397464.5
unk like zinc finger
chr13_-_96994350 0.07 ENST00000298440.5
ENST00000543457.6
ENST00000541038.2
oxoglutarate receptor 1
chr19_+_36916298 0.07 ENST00000427117.5
ENST00000333987.12
ENST00000587130.5
ENST00000415168.5
ENST00000444991.5
zinc finger protein 568

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.2 0.6 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.1 0.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.5 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 1.2 GO:0030091 protein repair(GO:0030091)
0.1 1.2 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.3 GO:0060913 cardiac cell fate determination(GO:0060913) negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0061011 hepatic duct development(GO:0061011)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.3 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.3 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 1.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:0018032 protein amidation(GO:0018032)
0.1 0.2 GO:0060032 notochord regression(GO:0060032)
0.0 0.4 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.1 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.2 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:0048294 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.2 GO:0061518 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:2000078 positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.1 GO:0044335 canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.0 0.1 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.0 0.1 GO:0045082 interleukin-13 biosynthetic process(GO:0042231) positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.6 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 2.2 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.0 0.0 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 1.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 2.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 1.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.2 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 3.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 2.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors