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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TBX3

Z-value: 0.96

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Transcription factors associated with TBX3

Gene Symbol Gene ID Gene Info
ENSG00000135111.16 T-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX3hg38_v1_chr12_-_114683590_114683652,
hg38_v1_chr12_-_114684151_114684221
-0.285.0e-01Click!

Activity profile of TBX3 motif

Sorted Z-values of TBX3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_242449478 1.27 ENST00000427495.5
phospholipase D family member 5
chr4_+_40193642 1.25 ENST00000617441.4
ENST00000503941.5
ras homolog family member H
chr1_-_209652329 1.12 ENST00000367030.7
ENST00000356082.9
laminin subunit beta 3
chr19_-_35513641 1.09 ENST00000339686.8
ENST00000447113.6
dermokine
chr9_+_122519141 0.74 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr3_+_189631373 0.64 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
tumor protein p63
chr2_+_17540670 0.62 ENST00000451533.5
ENST00000295156.9
visinin like 1
chr1_-_183590876 0.61 ENST00000367536.5
neutrophil cytosolic factor 2
chr8_-_138914034 0.61 ENST00000303045.11
collagen type XXII alpha 1 chain
chr21_-_44920918 0.58 ENST00000522688.5
integrin subunit beta 2
chr2_+_17541157 0.57 ENST00000406397.1
visinin like 1
chr1_+_26543106 0.51 ENST00000530003.5
ribosomal protein S6 kinase A1
chr8_+_32646838 0.47 ENST00000651333.1
ENST00000652592.1
neuregulin 1
chr19_-_32869741 0.43 ENST00000590341.5
ENST00000587772.1
ENST00000023064.9
solute carrier family 7 member 9
chr12_-_6374803 0.41 ENST00000396966.6
sodium channel epithelial 1 subunit alpha
chr10_+_69801874 0.40 ENST00000357811.8
collagen type XIII alpha 1 chain
chr14_-_91867529 0.40 ENST00000435962.7
tandem C2 domains, nuclear
chr6_+_121435595 0.40 ENST00000649003.1
ENST00000282561.4
gap junction protein alpha 1
chr19_-_51027662 0.38 ENST00000594768.5
kallikrein related peptidase 11
chr4_-_79326008 0.38 ENST00000286794.5
N-alpha-acetyltransferase 11, NatA catalytic subunit
chr22_-_20268285 0.38 ENST00000043402.8
reticulon 4 receptor
chr22_-_40862070 0.38 ENST00000307221.5
DnaJ heat shock protein family (Hsp40) member B7
chr11_+_19117123 0.37 ENST00000399351.7
ENST00000446113.7
zinc finger DHHC-type palmitoyltransferase 13
chr17_+_76376581 0.37 ENST00000591651.5
ENST00000545180.5
sphingosine kinase 1
chr19_-_51028015 0.37 ENST00000319720.11
kallikrein related peptidase 11
chr15_-_59372863 0.35 ENST00000288235.9
myosin IE
chr9_-_98192614 0.33 ENST00000375077.5
coronin 2A
chr15_-_74725370 0.33 ENST00000567032.5
ENST00000564596.5
ENST00000566503.1
ENST00000395049.8
ENST00000379727.8
ENST00000617691.4
ENST00000395048.6
cytochrome P450 family 1 subfamily A member 1
chr7_-_93890160 0.32 ENST00000451238.1
tissue factor pathway inhibitor 2
chr11_+_34622053 0.32 ENST00000530286.5
ENST00000533754.5
ETS homologous factor
chr1_+_212035717 0.31 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr19_-_51027954 0.31 ENST00000391804.7
kallikrein related peptidase 11
chr2_+_113117889 0.31 ENST00000361779.7
ENST00000259206.9
ENST00000354115.6
interleukin 1 receptor antagonist
chr19_+_1077394 0.30 ENST00000590577.2
Rho GTPase activating protein 45
chrX_-_57680260 0.30 ENST00000434992.1
NLR family pyrin domain containing 2B
chr9_-_111328520 0.29 ENST00000374428.1
olfactory receptor family 2 subfamily K member 2
chr17_-_2336435 0.29 ENST00000301364.10
ENST00000576112.2
TSR1 ribosome maturation factor
chr19_+_9185594 0.29 ENST00000344248.4
olfactory receptor family 7 subfamily D member 2
chr3_-_121545962 0.28 ENST00000264233.6
DNA polymerase theta
chr1_-_160098675 0.28 ENST00000368086.5
ENST00000614243.4
ENST00000448417.1
immunoglobulin superfamily member 8
chr12_+_6226136 0.28 ENST00000676764.1
ENST00000646407.1
CD9 molecule
chr6_-_32853618 0.26 ENST00000354258.5
transporter 1, ATP binding cassette subfamily B member
chr4_+_177309866 0.25 ENST00000264596.4
nei like DNA glycosylase 3
chr6_-_32853813 0.25 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr2_+_202073282 0.25 ENST00000459709.5
KIAA2012
chr12_+_78036248 0.24 ENST00000644176.1
neuron navigator 3
chr2_+_202073249 0.24 ENST00000498697.3
KIAA2012
chr4_+_102869332 0.24 ENST00000503643.1
CDGSH iron sulfur domain 2
chr21_+_42499600 0.24 ENST00000398341.7
solute carrier family 37 member 1
chr17_+_55751378 0.24 ENST00000325214.10
phosphatidylcholine transfer protein
chr11_-_78139258 0.24 ENST00000530910.6
ENST00000681417.1
ENST00000681225.1
ENST00000681765.1
ENST00000525870.6
ENST00000530608.6
ENST00000532306.6
ENST00000376156.7
ENST00000681699.1
ENST00000681221.1
ENST00000679444.1
ENST00000680829.1
ENST00000680761.1
ENST00000680256.1
ENST00000525783.6
ENST00000529139.6
ENST00000680580.1
ENST00000526849.6
ENST00000680399.1
ENST00000527099.2
ENST00000681489.1
ENST00000299626.10
ENST00000679497.1
ENST00000680101.1
ENST00000532440.6
ENST00000530454.6
ENST00000525761.3
ENST00000681575.1
ENST00000679559.1
ENST00000680398.1
ENST00000615266.5
ENST00000680643.1
ALG8 alpha-1,3-glucosyltransferase
chr19_-_36152427 0.23 ENST00000589154.1
ENST00000292907.8
cytochrome c oxidase subunit 7A1
chr11_-_62839564 0.22 ENST00000311713.11
ENST00000278856.9
WD repeat domain 74
chr3_-_172711005 0.22 ENST00000424772.2
ENST00000475381.7
neutral cholesterol ester hydrolase 1
chr1_-_9910169 0.22 ENST00000377263.6
catenin beta interacting protein 1
chr1_-_152580511 0.22 ENST00000368787.4
late cornified envelope 3D
chr8_-_80171106 0.21 ENST00000519303.6
tumor protein D52
chr16_+_84768246 0.21 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr15_+_79311084 0.20 ENST00000299705.10
transmembrane p24 trafficking protein 3
chr8_+_22059198 0.20 ENST00000523266.5
ENST00000519907.5
dematin actin binding protein
chrX_-_54798253 0.20 ENST00000218436.7
inter-alpha-trypsin inhibitor heavy chain family member 6
chr6_-_46735693 0.20 ENST00000537365.1
phospholipase A2 group VII
chr12_+_1691011 0.20 ENST00000357103.5
adiponectin receptor 2
chr15_+_79311137 0.20 ENST00000424155.6
ENST00000536821.5
transmembrane p24 trafficking protein 3
chr8_+_22059169 0.20 ENST00000358242.5
dematin actin binding protein
chr3_+_57756230 0.20 ENST00000295951.7
ENST00000659705.1
ENST00000671191.1
sarcolemma associated protein
chr15_+_40569290 0.19 ENST00000315616.12
ENST00000559271.1
ENST00000616318.1
RNA pseudouridine synthase domain containing 2
chr15_+_66453418 0.19 ENST00000566326.1
mitogen-activated protein kinase kinase 1
chr7_-_135211313 0.19 ENST00000682802.1
ENST00000683848.1
ENST00000354475.5
WD repeat domain 91
chr7_+_150567347 0.19 ENST00000461940.5
GTPase, IMAP family member 4
chr12_+_88142290 0.19 ENST00000549011.5
ENST00000551088.1
ENST00000266712.11
transmembrane O-mannosyltransferase targeting cadherins 3
chr3_+_130081831 0.18 ENST00000425059.1
ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like 2
chr3_+_149474688 0.18 ENST00000305354.5
ENST00000465758.1
transmembrane 4 L six family member 4
chr20_+_8789517 0.18 ENST00000437439.2
phospholipase C beta 1
chr13_-_103066411 0.18 ENST00000245312.5
solute carrier family 10 member 2
chr17_+_55751021 0.18 ENST00000268896.10
ENST00000576183.5
ENST00000573500.5
phosphatidylcholine transfer protein
chr16_+_50065959 0.18 ENST00000299192.8
HEAT repeat containing 3
chr12_+_12070932 0.18 ENST00000308721.9
BCL2 like 14
chr8_+_97887903 0.17 ENST00000520016.5
matrilin 2
chr1_-_155990062 0.17 ENST00000462460.6
Rho/Rac guanine nucleotide exchange factor 2
chr4_+_122379508 0.17 ENST00000388725.2
adenosine deaminase domain containing 1
chr8_-_63026179 0.16 ENST00000677919.1
gamma-glutamyl hydrolase
chr8_+_132919403 0.16 ENST00000519178.5
thyroglobulin
chr2_-_88992903 0.16 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr4_-_6200520 0.15 ENST00000409021.9
ENST00000409371.8
ENST00000282924.9
ENST00000531445.3
janus kinase and microtubule interacting protein 1
chromosome 4 open reading frame 50
chr14_+_77457861 0.15 ENST00000555133.5
activator of HSP90 ATPase activity 1
chr11_+_59172116 0.15 ENST00000227451.4
deltex E3 ubiquitin ligase 4
chr14_+_21317535 0.15 ENST00000382933.8
RPGR interacting protein 1
chr1_+_171781635 0.15 ENST00000361735.4
ENST00000362019.7
ENST00000367737.9
eEF1A lysine and N-terminal methyltransferase
chr5_-_160312756 0.15 ENST00000644313.1
cyclin J like
chr15_-_74208969 0.15 ENST00000423167.6
ENST00000432245.6
signaling receptor and transporter of retinol STRA6
chr1_+_220094086 0.14 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chr11_-_105023136 0.14 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr3_-_42410558 0.14 ENST00000441172.1
ENST00000287748.8
lysozyme like 4
chr11_-_1608463 0.14 ENST00000399685.1
keratin associated protein 5-3
chr12_+_48482492 0.14 ENST00000548364.7
chromosome 12 open reading frame 54
chr19_+_36100593 0.13 ENST00000680211.1
WD repeat domain 62
chr10_-_125881282 0.13 ENST00000284690.4
DEAH-box helicase 32 (putative)
chr2_+_32277883 0.13 ENST00000238831.9
Yip1 domain family member 4
chr12_-_53335737 0.13 ENST00000303846.3
Sp7 transcription factor
chrX_+_23908006 0.12 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chr19_-_55279690 0.12 ENST00000587959.1
ENST00000585927.1
ENST00000587922.5
ENST00000585698.1
HSPA (Hsp70) binding protein 1
chr11_+_71538025 0.12 ENST00000398534.4
keratin associated protein 5-8
chrX_-_132489015 0.12 ENST00000421707.1
ENST00000370853.8
muscleblind like splicing regulator 3
chr19_-_42427379 0.12 ENST00000244289.9
lipase E, hormone sensitive type
chr7_+_150737382 0.11 ENST00000358647.5
GTPase, IMAP family member 5
chr20_-_1491407 0.11 ENST00000359801.8
signal regulatory protein beta 2
chr11_+_26332117 0.11 ENST00000531646.1
ENST00000256737.8
anoctamin 3
chr3_+_124384950 0.11 ENST00000683146.1
kalirin RhoGEF kinase
chr19_-_41428730 0.11 ENST00000321702.2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr3_+_124384513 0.11 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
kalirin RhoGEF kinase
chr21_-_14546351 0.11 ENST00000619120.4
SAM domain, SH3 domain and nuclear localization signals 1
chr11_+_71527267 0.10 ENST00000398536.6
keratin associated protein 5-7
chr3_+_119147375 0.10 ENST00000490594.2
novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)
chr19_-_10380454 0.10 ENST00000530829.1
ENST00000529370.5
tyrosine kinase 2
chr7_+_73692596 0.10 ENST00000453316.1
BUD23 rRNA methyltransferase and ribosome maturation factor
chr7_-_86965872 0.10 ENST00000398276.6
ENST00000416314.5
ENST00000425689.1
endosome-lysosome associated apoptosis and autophagy regulator family member 2
chr22_-_41285868 0.10 ENST00000422838.1
ENST00000405486.5
Ran GTPase activating protein 1
chr14_-_74875998 0.09 ENST00000556489.4
ENST00000673765.1
prospero homeobox 2
chr1_+_196888014 0.09 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
complement factor H related 4
chrX_+_44844015 0.09 ENST00000339042.6
dual specificity phosphatase 21
chr12_-_69699331 0.09 ENST00000548658.1
ENST00000476098.5
bestrophin 3
chr13_-_72782096 0.09 ENST00000545453.5
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
chr6_+_29585121 0.09 ENST00000641840.1
olfactory receptor family 2 subfamily H member 2
chr2_+_202265721 0.09 ENST00000264279.10
NOP58 ribonucleoprotein
chr6_+_26087417 0.09 ENST00000357618.10
ENST00000309234.10
homeostatic iron regulator
chr12_+_16347637 0.09 ENST00000543076.5
ENST00000396210.8
microsomal glutathione S-transferase 1
chr17_-_7114240 0.09 ENST00000446679.6
asialoglycoprotein receptor 2
chr19_-_38878247 0.08 ENST00000591812.2
Ras and Rab interactor like
chr21_-_14546297 0.08 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr9_+_100442271 0.08 ENST00000502978.1
MSANTD3-TMEFF1 readthrough
chr22_+_24603147 0.08 ENST00000412658.5
ENST00000445029.5
ENST00000400382.6
ENST00000419133.5
ENST00000438643.6
ENST00000452551.5
ENST00000412898.5
ENST00000400380.5
ENST00000455483.5
ENST00000430289.5
gamma-glutamyltransferase 1
chr12_+_16347665 0.08 ENST00000535309.5
ENST00000540056.5
ENST00000396209.5
ENST00000540126.5
microsomal glutathione S-transferase 1
chr9_+_273026 0.08 ENST00000682249.1
ENST00000453981.5
ENST00000487230.5
ENST00000469391.5
dedicator of cytokinesis 8
chr20_-_5950463 0.08 ENST00000203001.7
ENST00000453074.6
tRNA methyltransferase 6
chr3_+_139343996 0.08 ENST00000680020.1
ENST00000310776.9
ENST00000465373.5
mitochondrial ribosomal protein S22
chr19_+_21082140 0.08 ENST00000616183.1
ENST00000596053.5
zinc finger protein 714
chr5_-_138274610 0.08 ENST00000274721.8
GDNF family receptor alpha 3
chr1_-_37765105 0.08 ENST00000373048.9
ENST00000319637.6
EPH receptor A10
chrX_-_149631787 0.08 ENST00000600449.8
ENST00000611119.4
transmembrane protein 185A
chr1_+_248508073 0.08 ENST00000641804.1
olfactory receptor family 2 subfamily G member 6
chr2_+_216109323 0.08 ENST00000392132.7
ENST00000417391.1
X-ray repair cross complementing 5
chr22_+_22895368 0.08 ENST00000390321.2
immunoglobulin lambda constant 1
chr12_+_123671105 0.08 ENST00000680574.1
ENST00000426174.6
ENST00000679504.1
ENST00000303372.7
tectonic family member 2
chr6_-_169250825 0.08 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr11_-_122116215 0.07 ENST00000560104.2
BH3-like motif containing, cell death inducer
chr2_-_26346755 0.07 ENST00000651242.1
ENST00000433584.1
ENST00000333478.10
adhesion G protein-coupled receptor F3
chr4_+_154563003 0.07 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chr6_-_73225465 0.07 ENST00000370388.4
KH domain containing 1 like
chr5_-_138274565 0.07 ENST00000378362.3
GDNF family receptor alpha 3
chr3_+_124384757 0.07 ENST00000684374.1
kalirin RhoGEF kinase
chr4_+_70195719 0.07 ENST00000683306.1
odontogenic, ameloblast associated
chr19_+_19211949 0.07 ENST00000252575.11
neurocan
chr3_-_98035295 0.07 ENST00000621172.4
gamma-aminobutyric acid type A receptor subunit rho3
chr11_+_71548420 0.07 ENST00000528743.4
keratin associated protein 5-9
chr2_+_66439294 0.07 ENST00000495021.6
Meis homeobox 1
chr16_-_18868218 0.07 ENST00000566328.2
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr9_-_68540879 0.07 ENST00000377311.4
transmembrane protein 252
chr9_+_111525148 0.07 ENST00000358151.8
ENST00000309235.6
ENST00000355824.7
ENST00000374374.3
zinc finger protein 483
chr13_-_46105009 0.07 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
carboxypeptidase B2
chr11_-_61161414 0.07 ENST00000301765.10
VPS37C subunit of ESCRT-I
chr15_-_42920638 0.06 ENST00000566931.1
ENST00000564431.5
ENST00000567274.5
ENST00000267890.11
tau tubulin kinase 2
chr2_-_178108339 0.06 ENST00000358450.8
phosphodiesterase 11A
chr17_-_14236862 0.06 ENST00000420162.7
ENST00000431716.2
CMT1A duplicated region transcript 15
chr8_-_22156741 0.06 ENST00000424267.6
leucine rich repeat LGI family member 3
chr8_+_143684448 0.06 ENST00000534303.5
ENST00000529833.5
ENST00000530574.5
ENST00000358656.9
ENST00000442058.6
ENST00000526970.5
ENST00000532158.5
zinc finger protein 707
chr8_-_22156789 0.06 ENST00000306317.7
leucine rich repeat LGI family member 3
chr10_+_25174969 0.06 ENST00000376351.4
G protein-coupled receptor 158
chr2_-_208254232 0.06 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chr22_+_22720615 0.06 ENST00000390309.2
immunoglobulin lambda variable 3-19
chr12_-_54364467 0.06 ENST00000267015.4
ENST00000551809.1
G protein-coupled receptor 84
chr20_+_56533246 0.06 ENST00000371325.1
family with sequence similarity 209 member B
chr2_-_89010515 0.06 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr7_+_144086278 0.06 ENST00000641592.1
olfactory receptor family 2 subfamily A member 12
chr8_+_143684499 0.05 ENST00000526315.5
ENST00000532205.5
zinc finger protein 707
chr2_+_233729042 0.05 ENST00000482026.6
UDP glucuronosyltransferase family 1 member A3
chr6_+_42155399 0.05 ENST00000623004.2
ENST00000372963.4
ENST00000654459.1
GUCA1A neighbor
guanylate cyclase activator 1A
chr14_+_22207502 0.05 ENST00000390461.2
T cell receptor alpha variable 34
chr19_-_42220109 0.05 ENST00000595337.5
death effector domain containing 2
chr3_+_139344530 0.05 ENST00000478464.5
mitochondrial ribosomal protein S22
chr14_+_30874745 0.05 ENST00000556908.5
ENST00000555881.5
ENST00000460581.6
ENST00000643575.1
cochlin
chr20_+_58150896 0.05 ENST00000371168.4
chromosome 20 open reading frame 85
chr19_-_51034840 0.05 ENST00000529888.5
kallikrein related peptidase 12
chr11_+_78063851 0.05 ENST00000281030.2
thyroid hormone responsive
chr12_-_69699285 0.05 ENST00000553096.5
ENST00000330891.10
bestrophin 3
chr14_-_74302910 0.05 ENST00000556971.1
ENST00000356924.9
ATP binding cassette subfamily D member 4
chr12_-_88142040 0.05 ENST00000552810.6
ENST00000673058.2
ENST00000675833.1
ENST00000675476.1
ENST00000309041.12
ENST00000675408.1
ENST00000675230.1
ENST00000397838.8
ENST00000552770.3
centrosomal protein 290
chr5_-_135954962 0.05 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr19_-_51034892 0.05 ENST00000319590.8
ENST00000250351.4
kallikrein related peptidase 12
chr17_-_57745292 0.05 ENST00000299415.3
coiled-coil domain containing 182
chr11_-_123061173 0.05 ENST00000526110.5
ENST00000227378.7
heat shock protein family A (Hsp70) member 8
chr14_+_69767093 0.05 ENST00000394366.6
serine and arginine rich splicing factor 5
chr2_+_23927309 0.05 ENST00000404924.5
UBX domain protein 2A
chr14_+_73950285 0.05 ENST00000334571.7
ENST00000554920.5
coenzyme Q6, monooxygenase
chr10_+_25174796 0.04 ENST00000650135.1
G protein-coupled receptor 158
chr2_-_23927107 0.04 ENST00000238789.10
ATPase family AAA domain containing 2B
chr6_-_111605859 0.04 ENST00000651359.1
ENST00000650859.1
ENST00000359831.8
ENST00000368761.11
TRAF3 interacting protein 2
chr2_-_216694794 0.04 ENST00000449583.1
insulin like growth factor binding protein 5
chr19_+_40751179 0.04 ENST00000243563.8
ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr6_-_55579160 0.04 ENST00000370850.6
3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 0.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.2 0.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.4 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.3 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.1 0.4 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.4 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.4 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0070476 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:1904432 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.6 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.1 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 1.2 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.3 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.4 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.3 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.3 GO:0034115 negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
0.0 0.1 GO:0061741 vacuolar transmembrane transport(GO:0034486) chaperone-mediated protein transport involved in chaperone-mediated autophagy(GO:0061741) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.6 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.0 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.5 GO:0042825 TAP complex(GO:0042825)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.2 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.5 GO:0015440 peptide-transporting ATPase activity(GO:0015440) MHC class Ib protein binding(GO:0023029) TAP2 binding(GO:0046979)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033) dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.4 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1