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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TGIF1

Z-value: 1.16

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Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
ENSG00000177426.22 TGFB induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF1hg38_v1_chr18_+_3449413_34496190.561.5e-01Click!

Activity profile of TGIF1 motif

Sorted Z-values of TGIF1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_33134579 2.53 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr2_+_33134620 2.46 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr3_+_45026296 2.22 ENST00000296130.5
C-type lectin domain family 3 member B
chr15_+_32717994 2.13 ENST00000560677.5
ENST00000560830.1
ENST00000651154.1
gremlin 1, DAN family BMP antagonist
chr1_+_163068775 1.80 ENST00000421743.6
regulator of G protein signaling 4
chr15_+_32718476 1.67 ENST00000652365.1
gremlin 1, DAN family BMP antagonist
chr5_-_19988179 1.30 ENST00000502796.5
ENST00000382275.6
ENST00000511273.1
cadherin 18
chr13_-_37598750 1.23 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr2_+_24491860 0.98 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr4_+_54229261 0.94 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr17_-_55732074 0.91 ENST00000575734.5
transmembrane protein 100
chr4_-_174522791 0.91 ENST00000541923.5
ENST00000542498.5
15-hydroxyprostaglandin dehydrogenase
chr4_-_174522446 0.90 ENST00000296521.11
ENST00000296522.11
ENST00000422112.6
ENST00000504433.1
15-hydroxyprostaglandin dehydrogenase
chr5_-_128538230 0.85 ENST00000262464.9
fibrillin 2
chr3_+_69739425 0.83 ENST00000352241.9
ENST00000642352.1
melanocyte inducing transcription factor
chr1_+_6555301 0.80 ENST00000333172.11
ENST00000351136.7
taste 1 receptor member 1
chr10_-_77638369 0.79 ENST00000372443.6
potassium calcium-activated channel subfamily M alpha 1
chr10_+_68109433 0.79 ENST00000613327.4
ENST00000358913.10
ENST00000373675.3
myopalladin
chr11_+_72227881 0.78 ENST00000538751.5
ENST00000541756.5
inositol polyphosphate phosphatase like 1
chr1_-_149917826 0.76 ENST00000369145.1
ENST00000369146.8
synaptic vesicle glycoprotein 2A
chr4_-_174522315 0.73 ENST00000514584.5
15-hydroxyprostaglandin dehydrogenase
chr16_+_2830155 0.73 ENST00000382280.7
zymogen granule protein 16B
chr9_-_76692181 0.73 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chrX_+_9543103 0.72 ENST00000683056.1
transducin beta like 1 X-linked
chr7_-_23347704 0.71 ENST00000619562.4
insulin like growth factor 2 mRNA binding protein 3
chr16_+_2830368 0.69 ENST00000572863.1
zymogen granule protein 16B
chr10_+_52314272 0.68 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr12_+_108515262 0.68 ENST00000552695.6
ENST00000552758.1
ENST00000361549.2
FIC domain protein adenylyltransferase
chr17_-_68955332 0.68 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chrX_+_9786420 0.66 ENST00000380913.8
shroom family member 2
chr12_+_65279445 0.65 ENST00000642404.1
methionine sulfoxide reductase B3
chr11_+_111976902 0.63 ENST00000614104.4
DIX domain containing 1
chr20_+_36214373 0.62 ENST00000432603.1
erythrocyte membrane protein band 4.1 like 1
chr2_-_43676406 0.61 ENST00000475092.4
C1GALT1 specific chaperone 1 like
chr2_+_127419882 0.61 ENST00000409048.1
protein C, inactivator of coagulation factors Va and VIIIa
chr10_-_48652493 0.60 ENST00000435790.6
Rho GTPase activating protein 22
chr11_+_6390439 0.59 ENST00000530395.1
ENST00000342245.9
ENST00000527275.5
sphingomyelin phosphodiesterase 1
chr2_+_24491239 0.59 ENST00000348332.8
nuclear receptor coactivator 1
chr1_-_208244375 0.59 ENST00000367033.4
plexin A2
chr3_-_15797930 0.58 ENST00000683139.1
ankyrin repeat domain 28
chr5_+_141364153 0.57 ENST00000518069.2
protocadherin gamma subfamily A, 5
chr11_+_12110569 0.57 ENST00000683283.1
ENST00000256194.8
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr18_-_56638427 0.57 ENST00000586262.5
ENST00000217515.11
thioredoxin like 1
chr5_+_141969074 0.53 ENST00000506938.5
ENST00000394520.7
ENST00000394514.6
ENST00000512565.5
ring finger protein 14
chr17_+_70169516 0.53 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr5_-_160370619 0.52 ENST00000652664.2
ENST00000393975.4
C1q and TNF related 2
chr3_-_127822835 0.52 ENST00000453507.6
monoglyceride lipase
chr16_+_2830179 0.52 ENST00000570670.5
zymogen granule protein 16B
chr3_-_52685794 0.52 ENST00000424867.1
ENST00000394830.7
ENST00000431678.5
ENST00000450271.5
polybromo 1
chr11_+_46295126 0.52 ENST00000534787.1
cAMP responsive element binding protein 3 like 1
chr7_+_95772506 0.51 ENST00000537881.5
ENST00000447467.6
ENST00000524053.5
ENST00000324972.10
ENST00000630942.2
ENST00000437599.5
ENST00000359388.8
ENST00000413338.5
dynein cytoplasmic 1 intermediate chain 1
chrX_-_100731504 0.51 ENST00000372989.5
ENST00000276141.10
synaptotagmin like 4
chr2_-_197310646 0.50 ENST00000647377.1
ankyrin repeat domain 44
chr6_-_31684040 0.50 ENST00000375863.7
lymphocyte antigen 6 family member G5C
chr6_+_101181254 0.49 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr5_+_76716094 0.49 ENST00000319211.5
coagulation factor II thrombin receptor
chr11_+_68008542 0.49 ENST00000614849.4
aldehyde dehydrogenase 3 family member B1
chr6_+_31655888 0.47 ENST00000375916.4
apolipoprotein M
chr10_-_48604952 0.47 ENST00000417912.6
Rho GTPase activating protein 22
chr16_+_2830295 0.47 ENST00000571723.1
zymogen granule protein 16B
chr4_+_76949807 0.46 ENST00000505788.5
ENST00000510515.5
ENST00000504637.5
septin 11
chr8_-_92017637 0.46 ENST00000422361.6
RUNX1 partner transcriptional co-repressor 1
chr6_+_72366730 0.46 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr5_+_76716182 0.44 ENST00000505600.1
coagulation factor II thrombin receptor
chr3_-_127822455 0.44 ENST00000265052.10
monoglyceride lipase
chr12_-_62935117 0.44 ENST00000228705.7
protein phosphatase, Mg2+/Mn2+ dependent 1H
chr5_-_88877967 0.43 ENST00000508610.5
ENST00000636294.1
myocyte enhancer factor 2C
chr2_+_227813834 0.42 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr10_-_14330879 0.42 ENST00000357447.7
FERM domain containing 4A
chr8_-_92017292 0.42 ENST00000521553.5
RUNX1 partner transcriptional co-repressor 1
chr3_-_127823177 0.41 ENST00000434178.6
monoglyceride lipase
chr10_+_88880236 0.41 ENST00000371926.8
STAM binding protein like 1
chr5_+_141330494 0.41 ENST00000517417.3
ENST00000378105.4
protocadherin gamma subfamily A, 1
chrX_-_49073989 0.41 ENST00000376386.3
ENST00000553851.3
PRA1 domain family member 2
chr3_-_127823235 0.41 ENST00000398104.5
monoglyceride lipase
chr15_+_75206398 0.39 ENST00000565074.1
chromosome 15 open reading frame 39
chr20_-_41317602 0.39 ENST00000559234.5
ENST00000683867.1
zinc fingers and homeoboxes 3
chr20_-_4015389 0.39 ENST00000336095.10
ring finger protein 24
chr4_+_186069144 0.38 ENST00000513189.1
ENST00000296795.8
toll like receptor 3
chr5_-_128538218 0.37 ENST00000502468.5
fibrillin 2
chr3_-_18424533 0.37 ENST00000417717.6
SATB homeobox 1
chr11_+_111977300 0.37 ENST00000615255.1
DIX domain containing 1
chr5_+_141489066 0.36 ENST00000252087.3
protocadherin gamma subfamily C, 5
chr16_+_27402167 0.36 ENST00000564089.5
ENST00000337929.8
interleukin 21 receptor
chr9_+_122510802 0.36 ENST00000335302.5
olfactory receptor family 1 subfamily J member 2
chr7_+_134866831 0.36 ENST00000435928.1
caldesmon 1
chr7_-_100895878 0.36 ENST00000419336.6
ENST00000241069.11
ENST00000411582.4
ENST00000302913.8
acetylcholinesterase (Cartwright blood group)
chr12_+_54854505 0.35 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr3_+_63911929 0.35 ENST00000487717.5
ataxin 7
chr16_+_2537997 0.34 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr11_-_111910888 0.34 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr9_-_16728165 0.34 ENST00000603713.5
ENST00000603313.5
basonuclin 2
chr15_-_43266857 0.34 ENST00000349114.8
ENST00000220420.10
transglutaminase 5
chr8_-_42207557 0.34 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
plasminogen activator, tissue type
chr11_-_111910830 0.34 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr20_+_44401397 0.34 ENST00000682427.1
ENST00000681977.1
ENST00000684136.1
ENST00000684046.1
ENST00000684476.1
ENST00000619550.5
ENST00000682169.1
hepatocyte nuclear factor 4 alpha
chr18_+_68798065 0.34 ENST00000360242.9
coiled-coil domain containing 102B
chr2_+_201116143 0.33 ENST00000443227.5
ENST00000309955.8
ENST00000341222.10
ENST00000341582.10
CASP8 and FADD like apoptosis regulator
chr16_+_50742059 0.33 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chr6_+_108559742 0.33 ENST00000343882.10
forkhead box O3
chrX_-_135296024 0.33 ENST00000370764.1
zinc finger protein 75D
chrX_-_103832204 0.33 ENST00000674363.1
ENST00000674162.1
ENST00000674338.1
ENST00000674274.1
ENST00000674271.1
ENST00000674265.1
ENST00000674212.1
ENST00000674255.1
ENST00000674342.1
ENST00000674430.1
ENST00000243298.3
novel transcript
RAB9B, member RAS oncogene family
chr22_-_35617321 0.32 ENST00000397326.7
ENST00000442617.1
myoglobin
chr12_+_104064520 0.32 ENST00000229330.9
host cell factor C2
chr11_-_63768762 0.32 ENST00000433688.2
chromosome 11 open reading frame 95
chr7_-_152435786 0.31 ENST00000682283.1
ENST00000679882.1
ENST00000452749.2
ENST00000683616.1
ENST00000262189.11
ENST00000683490.1
ENST00000681082.1
ENST00000684550.1
lysine methyltransferase 2C
chr17_+_28319149 0.31 ENST00000226230.8
ENST00000583381.5
ENST00000582113.1
ENST00000582384.1
transmembrane protein 97
chr2_-_197310767 0.31 ENST00000282272.15
ENST00000409153.5
ENST00000409919.5
ankyrin repeat domain 44
chr5_+_141968886 0.30 ENST00000347642.7
ring finger protein 14
chr4_+_127965267 0.30 ENST00000398965.5
abhydrolase domain containing 18
chr4_+_127965361 0.30 ENST00000444616.5
abhydrolase domain containing 18
chr6_+_83067655 0.30 ENST00000237163.9
ENST00000349129.7
DOP1 leucine zipper like protein A
chr16_-_67183948 0.30 ENST00000561621.5
ENST00000563902.2
ENST00000290881.11
KIAA0895 like
chr10_+_92848461 0.30 ENST00000443748.6
ENST00000371543.5
ENST00000260762.10
exocyst complex component 6
chr15_-_62060371 0.30 ENST00000644861.2
ENST00000645819.1
ENST00000395898.3
vacuolar protein sorting 13 homolog C
chr15_-_62060460 0.29 ENST00000249837.7
vacuolar protein sorting 13 homolog C
chr14_+_31025634 0.29 ENST00000673317.1
ENST00000556232.6
ENST00000542754.7
ENST00000554345.6
ENST00000334725.8
ENST00000554609.6
ENST00000313566.11
adaptor related protein complex 4 subunit sigma 1
chr10_+_123008966 0.29 ENST00000368869.8
ENST00000358776.7
acyl-CoA dehydrogenase short/branched chain
chr4_-_2418630 0.29 ENST00000511071.5
ENST00000290974.7
ENST00000509171.5
zinc finger FYVE-type containing 28
chr7_+_17299234 0.29 ENST00000637807.1
novel protein
chr2_+_201116238 0.29 ENST00000342795.9
CASP8 and FADD like apoptosis regulator
chr5_+_140125935 0.29 ENST00000333305.5
IgA inducing protein
chr20_-_5610980 0.28 ENST00000379019.7
glycerophosphocholine phosphodiesterase 1
chr20_-_63969890 0.28 ENST00000369888.6
zinc finger protein 512B
chr3_-_39192584 0.28 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
xin actin binding repeat containing 1
chr12_+_15322480 0.28 ENST00000674188.1
ENST00000281171.9
ENST00000543886.6
protein tyrosine phosphatase receptor type O
chr8_+_23288081 0.28 ENST00000265806.12
ENST00000519952.6
ENST00000518840.6
R3H domain and coiled-coil containing 1
chr9_+_34652167 0.28 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr6_-_111483700 0.28 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr4_-_127965133 0.28 ENST00000641558.1
ENST00000641590.1
ENST00000641503.1
ENST00000641482.1
ENST00000641743.1
ENST00000641369.1
ENST00000641949.1
ENST00000641695.1
ENST00000641509.1
ENST00000641243.1
ENST00000641686.2
ENST00000641690.1
ENST00000641228.1
ENST00000642042.1
major facilitator superfamily domain containing 8
chr9_-_130043154 0.28 ENST00000355681.3
ENST00000446176.7
ENST00000443566.6
ENST00000420781.5
formin binding protein 1
chr5_+_72848161 0.27 ENST00000506351.6
transportin 1
chr4_-_127965204 0.27 ENST00000513559.6
ENST00000641186.1
ENST00000641393.1
major facilitator superfamily domain containing 8
chr7_-_85187039 0.27 ENST00000284136.11
semaphorin 3D
chr3_+_123201920 0.27 ENST00000492595.6
ENST00000473494.6
ENST00000481965.6
SEC22 homolog A, vesicle trafficking protein
chr7_+_142770960 0.27 ENST00000632805.1
ENST00000633969.1
ENST00000539842.6
serine protease 2
chr19_-_10010492 0.27 ENST00000264828.4
collagen type V alpha 3 chain
chr13_+_95677107 0.27 ENST00000602402.6
ENST00000376795.6
DnaJ heat shock protein family (Hsp40) member C3
chr5_-_78985288 0.27 ENST00000264914.10
arylsulfatase B
chr6_-_43016856 0.27 ENST00000645375.1
ENST00000645410.1
male-enhanced antigen 1
chr3_-_3179674 0.27 ENST00000424814.5
ENST00000450014.1
ENST00000231948.9
ENST00000432408.6
ENST00000639284.1
cereblon
chr8_+_28317265 0.26 ENST00000301908.8
prepronociceptin
chr12_+_99647749 0.26 ENST00000324341.2
family with sequence similarity 71 member C
chr4_-_113761724 0.26 ENST00000511664.6
calcium/calmodulin dependent protein kinase II delta
chrX_-_72305892 0.26 ENST00000450875.5
ENST00000417400.1
ENST00000431381.5
ENST00000445983.5
ENST00000651998.1
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr12_+_15322529 0.26 ENST00000348962.7
protein tyrosine phosphatase receptor type O
chr12_+_15322257 0.26 ENST00000674316.1
protein tyrosine phosphatase receptor type O
chr1_+_150067668 0.26 ENST00000611412.4
ENST00000644510.2
ENST00000643611.1
vacuolar protein sorting 45 homolog
chr10_-_3785179 0.26 ENST00000469435.1
Kruppel like factor 6
chr18_+_3449413 0.26 ENST00000549253.5
TGFB induced factor homeobox 1
chr1_+_150067820 0.26 ENST00000419023.3
ENST00000644526.1
vacuolar protein sorting 45 homolog
chr4_-_2418608 0.26 ENST00000503000.1
zinc finger FYVE-type containing 28
chr14_+_100376398 0.26 ENST00000554998.5
ENST00000402312.8
ENST00000335290.10
ENST00000554175.5
WD repeat domain 25
chr4_+_165378998 0.25 ENST00000402744.9
carboxypeptidase E
chr14_-_72894091 0.25 ENST00000556509.6
double PHD fingers 3
chr5_-_132777404 0.25 ENST00000296873.11
septin 8
chr5_-_134632769 0.25 ENST00000505758.5
ENST00000439578.5
ENST00000502286.1
ENST00000402673.7
secretion associated Ras related GTPase 1B
chr3_-_190862688 0.24 ENST00000442080.6
geminin coiled-coil domain containing
chrX_+_110520312 0.24 ENST00000602699.1
teratocarcinoma-derived growth factor 1 pseudogene 3
chr1_+_52726441 0.24 ENST00000294353.7
ENST00000545132.5
zyg-11 family member B, cell cycle regulator
chr8_-_29263063 0.24 ENST00000524189.6
kinesin family member 13B
chr12_+_103587266 0.24 ENST00000388887.7
stabilin 2
chr11_+_121102666 0.24 ENST00000264037.2
tectorin alpha
chr1_+_150067279 0.24 ENST00000643970.1
ENST00000535106.5
ENST00000369128.9
vacuolar protein sorting 45 homolog
chr14_+_103100144 0.24 ENST00000380069.7
exocyst complex component 3 like 4
chr12_-_119804472 0.24 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chr15_+_75043263 0.24 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr4_-_113761441 0.23 ENST00000394524.7
calcium/calmodulin dependent protein kinase II delta
chr7_-_80512041 0.23 ENST00000398291.4
G protein subunit alpha transducin 3
chr8_+_133191029 0.23 ENST00000250160.11
cellular communication network factor 4
chrX_+_102712438 0.23 ENST00000486814.2
ENST00000535209.6
ENST00000543253.6
ENST00000332262.10
ENST00000483720.6
G protein-coupled receptor associated sorting protein 2
chr14_+_76761453 0.23 ENST00000167106.9
vasohibin 1
chr3_-_15798184 0.23 ENST00000624145.3
ankyrin repeat domain 28
chr9_-_96778053 0.23 ENST00000375231.5
ENST00000223428.9
zinc finger protein 510
chr11_-_6405405 0.23 ENST00000608645.5
ENST00000618005.4
ENST00000610474.4
ENST00000608394.5
ENST00000529519.5
amyloid beta precursor protein binding family B member 1
chr7_-_132576463 0.23 ENST00000423507.6
plexin A4
chr9_-_136764515 0.23 ENST00000316144.6
lipocalin 15
chr12_-_119804298 0.23 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr5_+_150508110 0.23 ENST00000261797.7
N-deacetylase and N-sulfotransferase 1
chr9_-_112890868 0.23 ENST00000374228.5
solute carrier family 46 member 2
chr10_+_119726118 0.22 ENST00000369081.3
ENST00000648262.1
inositol polyphosphate-5-phosphatase F
chr10_-_48274567 0.22 ENST00000636244.1
ENST00000374201.8
FERM and PDZ domain containing 2
chr19_+_37594830 0.22 ENST00000589117.5
zinc finger protein 540
chrX_+_154547606 0.22 ENST00000594239.6
ENST00000615874.4
ENST00000619941.4
ENST00000617207.4
ENST00000611176.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr11_-_111923722 0.22 ENST00000527950.5
crystallin alpha B
chr3_+_188154150 0.22 ENST00000617246.5
LIM domain containing preferred translocation partner in lipoma
chr1_+_240014319 0.22 ENST00000447095.5
formin 2
chr19_-_38224215 0.21 ENST00000355526.10
ENST00000420980.7
ENST00000614244.4
double PHD fingers 1
chr2_+_37084486 0.21 ENST00000281932.6
ENST00000674370.2
G-patch domain containing 11
chr16_+_2148603 0.21 ENST00000210187.11
RAB26, member RAS oncogene family
chr5_-_132777371 0.21 ENST00000620483.4
septin 8
chr17_-_81911200 0.21 ENST00000570391.5
phosphate cytidylyltransferase 2, ethanolamine
chr20_-_33720221 0.21 ENST00000409299.8
ENST00000217398.3
ENST00000344022.7
peroxisomal membrane protein 4
chr3_+_112562059 0.21 ENST00000261034.6
solute carrier family 35 member A5
chr9_-_16727980 0.21 ENST00000418777.5
ENST00000468187.6
basonuclin 2
chr2_+_61905646 0.20 ENST00000311832.5
copper metabolism domain containing 1
chr11_+_64284982 0.20 ENST00000539833.5
G protein-coupled receptor 137
chr1_-_169630115 0.20 ENST00000263686.11
ENST00000367788.6
selectin P
chr2_+_37084440 0.20 ENST00000409774.6
G-patch domain containing 11
chr3_+_112562030 0.20 ENST00000468642.5
ENST00000492406.6
solute carrier family 35 member A5

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.8 6.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.5 1.6 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.3 0.9 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 0.9 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.3 1.2 GO:1990523 bone regeneration(GO:1990523)
0.2 0.7 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2 2.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.2 0.6 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 2.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 0.8 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 1.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.2 0.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 1.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.4 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.4 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.2 GO:1904397 negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.4 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.5 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.3 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.4 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.1 0.6 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.4 GO:0034343 microglial cell activation involved in immune response(GO:0002282) type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.8 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.7 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.3 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.8 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 1.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.8 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.6 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.3 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.7 GO:0030091 protein repair(GO:0030091)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.4 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.2 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662)
0.1 0.3 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.7 GO:0045176 apical protein localization(GO:0045176)
0.1 0.3 GO:0070253 somatostatin secretion(GO:0070253)
0.1 0.5 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.1 GO:0072229 nitric oxide transport(GO:0030185) cerebrospinal fluid secretion(GO:0033326) cellular response to mercury ion(GO:0071288) proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.6 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.2 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 1.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.4 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:2000078 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.1 GO:1903217 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 2.5 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.5 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.0 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 1.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.8 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:1904526 regulation of microtubule binding(GO:1904526)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.3 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.5 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.8 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572) regulation of integrin activation(GO:0033623)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.1 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.9 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.2 GO:0042262 DNA protection(GO:0042262)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.5 GO:0060004 reflex(GO:0060004)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 1.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.1 GO:0060440 trachea formation(GO:0060440)
0.0 0.4 GO:0015813 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.0 0.1 GO:0060272 positive regulation of skeletal muscle fiber development(GO:0048743) embryonic skeletal joint morphogenesis(GO:0060272)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0001652 granular component(GO:0001652)
0.3 6.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 0.1 GO:0005715 late recombination nodule(GO:0005715)
0.0 0.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.6 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.3 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.6 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0044307 dendritic branch(GO:0044307)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.7 GO:0097542 ciliary tip(GO:0097542)
0.0 1.6 GO:0005902 microvillus(GO:0005902)
0.0 2.2 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.7 GO:0050436 microfibril binding(GO:0050436)
0.5 1.6 GO:0033142 progesterone receptor binding(GO:0033142)
0.5 2.5 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.3 3.8 GO:0016015 morphogen activity(GO:0016015)
0.3 0.9 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 1.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.9 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.1 1.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.8 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.4 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.2 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.8 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.5 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.8 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0042806 fucose binding(GO:0042806) glycosphingolipid binding(GO:0043208)
0.0 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.5 GO:0004030 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.9 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.5 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.4 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.7 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 2.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 2.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 6.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 3.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism