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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for TLX1_NFIC

Z-value: 0.61

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Transcription factors associated with TLX1_NFIC

Gene Symbol Gene ID Gene Info
TLX1
ENSG00000107807.13 T cell leukemia homeobox 1
NFIC
ENSG00000141905.19 nuclear factor I C

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIChg38_v1_chr19_+_3366549_33666210.196.5e-01Click!
TLX1hg38_v1_chr10_+_101131284_101131321-0.068.9e-01Click!

Activity profile of TLX1_NFIC motif

Sorted Z-values of TLX1_NFIC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_78620432 1.16 ENST00000370751.10
ENST00000459784.6
ENST00000680110.1
ENST00000680295.1
IFI44L
interferon induced protein 44 like
chr1_+_78620722 1.04 ENST00000679848.1
IFI44L
interferon induced protein 44 like
chr5_-_111757382 0.72 ENST00000453526.6
ENST00000509427.5
NREP
neuronal regeneration related protein
chr5_-_111757549 0.69 ENST00000419114.6
NREP
neuronal regeneration related protein
chr5_-_111757175 0.63 ENST00000509025.5
ENST00000257435.12
ENST00000515855.5
NREP
neuronal regeneration related protein
chr5_-_111757643 0.63 ENST00000508870.5
NREP
neuronal regeneration related protein
chr5_-_111757465 0.62 ENST00000446294.6
NREP
neuronal regeneration related protein
chr5_-_111757704 0.59 ENST00000379671.7
NREP
neuronal regeneration related protein
chr12_-_55712402 0.33 ENST00000452168.6
ITGA7
integrin subunit alpha 7
chr14_+_50533026 0.32 ENST00000441560.6
ATL1
atlastin GTPase 1
chr8_-_42207667 0.32 ENST00000352041.7
ENST00000679151.1
ENST00000679300.1
PLAT
plasminogen activator, tissue type
chr8_-_27611424 0.30 ENST00000405140.7
CLU
clusterin
chr13_+_31945826 0.30 ENST00000647500.1
FRY
FRY microtubule binding protein
chr8_-_42207557 0.28 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
PLAT
plasminogen activator, tissue type
chr21_-_26845402 0.28 ENST00000284984.8
ENST00000676955.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr10_+_122560639 0.27 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
DMBT1
deleted in malignant brain tumors 1
chr8_-_27611325 0.27 ENST00000523500.5
CLU
clusterin
chr10_+_122560679 0.26 ENST00000657942.1
DMBT1
deleted in malignant brain tumors 1
chr8_+_119416427 0.25 ENST00000259526.4
CCN3
cellular communication network factor 3
chr20_-_35438218 0.25 ENST00000374369.8
GDF5
growth differentiation factor 5
chr10_+_122560751 0.24 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
DMBT1
deleted in malignant brain tumors 1
chr11_-_5441514 0.24 ENST00000380211.1
OR51I1
olfactory receptor family 51 subfamily I member 1
chr17_-_15260752 0.24 ENST00000676329.1
ENST00000675551.1
ENST00000644020.1
ENST00000674947.1
PMP22
peripheral myelin protein 22
chr2_-_237414127 0.24 ENST00000472056.5
COL6A3
collagen type VI alpha 3 chain
chr2_-_237414157 0.23 ENST00000295550.9
ENST00000353578.9
ENST00000392004.7
ENST00000433762.1
ENST00000392003.6
COL6A3
collagen type VI alpha 3 chain
chr14_+_85530163 0.23 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_+_151540299 0.23 ENST00000392712.7
ENST00000368848.6
ENST00000368849.8
ENST00000353024.4
TUFT1
tuftelin 1
chr1_+_185734362 0.22 ENST00000271588.9
HMCN1
hemicentin 1
chr21_-_26843063 0.21 ENST00000678221.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr8_-_13276491 0.21 ENST00000512044.6
DLC1
DLC1 Rho GTPase activating protein
chr2_+_102104563 0.21 ENST00000409589.5
ENST00000409329.5
IL1R1
interleukin 1 receptor type 1
chr21_-_26843012 0.21 ENST00000517777.6
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr14_+_85530127 0.21 ENST00000330753.6
FLRT2
fibronectin leucine rich transmembrane protein 2
chr10_-_48251757 0.20 ENST00000305531.3
FRMPD2
FERM and PDZ domain containing 2
chr18_-_57803307 0.19 ENST00000648908.2
ATP8B1
ATPase phospholipid transporting 8B1
chrX_-_54798253 0.19 ENST00000218436.7
ITIH6
inter-alpha-trypsin inhibitor heavy chain family member 6
chr17_-_47821760 0.19 ENST00000613735.4
ENST00000007414.8
ENST00000392507.7
OSBPL7
oxysterol binding protein like 7
chr11_+_1223053 0.19 ENST00000529681.5
MUC5B
mucin 5B, oligomeric mucus/gel-forming
chr4_+_85827891 0.19 ENST00000514229.5
ARHGAP24
Rho GTPase activating protein 24
chr21_+_32412648 0.19 ENST00000401402.7
ENST00000382699.7
ENST00000300255.7
EVA1C
eva-1 homolog C
chr3_-_112638097 0.18 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr8_-_22927890 0.17 ENST00000256404.8
PEBP4
phosphatidylethanolamine binding protein 4
chr16_+_53099100 0.17 ENST00000565832.5
CHD9
chromodomain helicase DNA binding protein 9
chr12_-_52192007 0.17 ENST00000394815.3
KRT80
keratin 80
chr17_-_69327091 0.17 ENST00000592568.1
ENST00000392676.8
ABCA5
ATP binding cassette subfamily A member 5
chr22_-_36817510 0.17 ENST00000443735.1
PVALB
parvalbumin
chr3_+_63967738 0.17 ENST00000484332.1
ATXN7
ataxin 7
chr11_+_120240135 0.16 ENST00000543440.7
POU2F3
POU class 2 homeobox 3
chr19_-_11197516 0.16 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KANK2
KN motif and ankyrin repeat domains 2
chr12_-_52191981 0.16 ENST00000313234.9
KRT80
keratin 80
chr2_-_191847068 0.16 ENST00000304141.5
CAVIN2
caveolae associated protein 2
chr22_-_36817001 0.16 ENST00000406910.6
ENST00000417718.7
PVALB
parvalbumin
chr11_+_5389377 0.16 ENST00000328611.5
OR51M1
olfactory receptor family 51 subfamily M member 1
chr5_-_74641419 0.15 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ENC1
ectodermal-neural cortex 1
chr16_+_172869 0.15 ENST00000251595.11
ENST00000397806.1
ENST00000484216.1
HBA2
hemoglobin subunit alpha 2
chr1_-_201023694 0.15 ENST00000332129.6
ENST00000422435.2
ENST00000461742.7
KIF21B
kinesin family member 21B
chr12_-_55728436 0.15 ENST00000552692.5
CD63
CD63 molecule
chr1_+_240014319 0.15 ENST00000447095.5
FMN2
formin 2
chr16_-_51151259 0.15 ENST00000251020.9
SALL1
spalt like transcription factor 1
chr1_+_156126525 0.14 ENST00000504687.6
ENST00000473598.6
LMNA
lamin A/C
chr7_+_128715385 0.14 ENST00000315184.9
FAM71F1
family with sequence similarity 71 member F1
chr1_+_201739864 0.14 ENST00000367295.5
NAV1
neuron navigator 1
chr1_+_109910485 0.14 ENST00000525659.5
CSF1
colony stimulating factor 1
chr11_+_68008542 0.14 ENST00000614849.4
ALDH3B1
aldehyde dehydrogenase 3 family member B1
chr1_-_160885163 0.13 ENST00000326245.4
ITLN1
intelectin 1
chr12_+_13196718 0.13 ENST00000431267.2
ENST00000542474.5
ENST00000544053.5
ENST00000256951.10
EMP1
epithelial membrane protein 1
chr2_+_74002685 0.13 ENST00000305799.8
TET3
tet methylcytosine dioxygenase 3
chr11_-_10693740 0.13 ENST00000423302.7
IRAG1
inositol 1,4,5-triphosphate receptor associated 1
chr12_+_65824475 0.13 ENST00000403681.7
HMGA2
high mobility group AT-hook 2
chr2_+_68774921 0.13 ENST00000497079.5
ARHGAP25
Rho GTPase activating protein 25
chr16_+_28984795 0.13 ENST00000395461.7
LAT
linker for activation of T cells
chr17_-_78925376 0.13 ENST00000262768.11
TIMP2
TIMP metallopeptidase inhibitor 2
chr1_+_65309517 0.12 ENST00000371069.5
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6
chr5_+_141475928 0.12 ENST00000611950.1
ENST00000308177.5
ENST00000617641.4
ENST00000621008.1
ENST00000617222.4
PCDHGC3
protocadherin gamma subfamily C, 3
chr2_-_233013228 0.12 ENST00000264051.8
NGEF
neuronal guanine nucleotide exchange factor
chr22_-_24245059 0.12 ENST00000398292.3
ENST00000263112.11
ENST00000327365.10
ENST00000424217.1
GGT5
gamma-glutamyltransferase 5
chr1_-_160070102 0.12 ENST00000638728.1
ENST00000637644.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr11_+_72227881 0.12 ENST00000538751.5
ENST00000541756.5
INPPL1
inositol polyphosphate phosphatase like 1
chr15_+_70936487 0.12 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr8_-_143840940 0.12 ENST00000442628.7
NRBP2
nuclear receptor binding protein 2
chr10_-_126388455 0.12 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM12
ADAM metallopeptidase domain 12
chr4_-_65670478 0.12 ENST00000613740.5
ENST00000622150.4
ENST00000511294.1
EPHA5
EPH receptor A5
chr12_-_55728339 0.12 ENST00000552754.5
CD63
CD63 molecule
chr19_-_1812231 0.11 ENST00000587160.2
ENST00000310127.10
ENST00000526092.6
ATP8B3
ATPase phospholipid transporting 8B3
chr4_-_65670339 0.11 ENST00000273854.7
EPHA5
EPH receptor A5
chr3_+_170357647 0.11 ENST00000476188.5
ENST00000259119.9
ENST00000426052.6
SKIL
SKI like proto-oncogene
chr1_+_179293760 0.11 ENST00000367619.8
SOAT1
sterol O-acyltransferase 1
chr11_-_30586272 0.11 ENST00000448418.6
MPPED2
metallophosphoesterase domain containing 2
chr19_+_50432885 0.11 ENST00000357701.6
MYBPC2
myosin binding protein C2
chr1_+_179293714 0.11 ENST00000540564.5
ENST00000539888.5
SOAT1
sterol O-acyltransferase 1
chr16_-_3235143 0.11 ENST00000414144.7
ENST00000431561.7
ENST00000396870.8
ZNF200
zinc finger protein 200
chr5_+_170782682 0.11 ENST00000518525.5
ENST00000518122.5
GABRP
gamma-aminobutyric acid type A receptor subunit pi
chrX_-_149549924 0.11 ENST00000431993.4
HSFX3
heat shock transcription factor family, X-linked member 3
chr11_-_30586866 0.11 ENST00000528686.2
MPPED2
metallophosphoesterase domain containing 2
chr17_-_43833137 0.10 ENST00000398389.9
MPP3
membrane palmitoylated protein 3
chrX_-_119150579 0.10 ENST00000402510.2
KIAA1210
KIAA1210
chr16_-_19884828 0.10 ENST00000300571.7
ENST00000570142.5
ENST00000562469.5
GPRC5B
G protein-coupled receptor class C group 5 member B
chr11_-_10693955 0.10 ENST00000547195.5
IRAG1
inositol 1,4,5-triphosphate receptor associated 1
chr15_-_77071032 0.10 ENST00000559494.1
TSPAN3
tetraspanin 3
chr7_+_150368189 0.10 ENST00000519397.1
ENST00000479668.5
REPIN1
replication initiator 1
chr1_+_168280872 0.10 ENST00000367821.8
TBX19
T-box transcription factor 19
chr19_-_1812194 0.10 ENST00000525591.5
ATP8B3
ATPase phospholipid transporting 8B3
chr1_-_161223408 0.09 ENST00000491350.1
APOA2
apolipoprotein A2
chr5_+_68292562 0.09 ENST00000523872.1
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr9_-_76906090 0.09 ENST00000376718.8
PRUNE2
prune homolog 2 with BCH domain
chr11_-_111913134 0.09 ENST00000533971.2
ENST00000526180.6
CRYAB
crystallin alpha B
chr2_+_218672027 0.09 ENST00000392105.7
ENST00000455724.5
ENST00000295709.8
STK36
serine/threonine kinase 36
chr1_-_153544997 0.09 ENST00000368715.5
S100A4
S100 calcium binding protein A4
chr1_+_156126160 0.09 ENST00000448611.6
ENST00000368297.5
LMNA
lamin A/C
chr12_+_53097656 0.09 ENST00000301464.4
IGFBP6
insulin like growth factor binding protein 6
chr9_-_129753023 0.09 ENST00000340607.5
PTGES
prostaglandin E synthase
chr22_-_24005409 0.08 ENST00000621179.5
GSTT4
glutathione S-transferase theta 4
chr12_-_54419259 0.08 ENST00000293379.9
ITGA5
integrin subunit alpha 5
chr22_-_17258235 0.08 ENST00000649310.1
ENST00000649746.1
ADA2
adenosine deaminase 2
chr2_-_46916020 0.08 ENST00000409800.5
ENST00000409218.5
MCFD2
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr1_-_160070150 0.08 ENST00000644903.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr11_-_62689523 0.08 ENST00000317449.5
LRRN4CL
LRRN4 C-terminal like
chr11_-_111913195 0.08 ENST00000531198.5
ENST00000616970.5
ENST00000527899.6
CRYAB
crystallin alpha B
chrX_-_13938378 0.08 ENST00000398361.7
GPM6B
glycoprotein M6B
chr8_-_93740718 0.08 ENST00000519109.6
RBM12B
RNA binding motif protein 12B
chr2_+_218672291 0.08 ENST00000440309.5
ENST00000424080.1
STK36
serine/threonine kinase 36
chr9_-_76906041 0.08 ENST00000443509.6
ENST00000428286.5
ENST00000376713.3
PRUNE2
prune homolog 2 with BCH domain
chr9_-_127854636 0.08 ENST00000344849.4
ENST00000373203.9
ENG
endoglin
chr12_+_57128475 0.08 ENST00000243077.8
ENST00000553277.5
LRP1
LDL receptor related protein 1
chr22_+_30396991 0.08 ENST00000617837.4
ENST00000615189.5
ENST00000405717.7
ENST00000402592.7
SEC14L2
SEC14 like lipid binding 2
chr1_+_78649818 0.08 ENST00000370747.9
ENST00000438486.1
IFI44
interferon induced protein 44
chrX_-_84502442 0.08 ENST00000297977.9
ENST00000506585.6
ENST00000373177.3
ENST00000449553.2
HDX
highly divergent homeobox
chr16_-_2214776 0.07 ENST00000333503.8
PGP
phosphoglycolate phosphatase
chr15_-_68432151 0.07 ENST00000423218.6
ENST00000315757.9
ITGA11
integrin subunit alpha 11
chr1_-_230978796 0.07 ENST00000522821.5
ENST00000366662.8
ENST00000366661.9
ENST00000522399.1
TTC13
tetratricopeptide repeat domain 13
chr14_+_94581388 0.07 ENST00000554866.5
ENST00000556775.5
SERPINA5
serpin family A member 5
chr8_-_37965953 0.07 ENST00000647937.1
ENSG00000285880.1
ADRB3-GOT1L1 readthrough
chr1_-_31704001 0.07 ENST00000373672.8
COL16A1
collagen type XVI alpha 1 chain
chr11_-_65558338 0.07 ENST00000301873.11
LTBP3
latent transforming growth factor beta binding protein 3
chr9_-_14910421 0.07 ENST00000380880.4
FREM1
FRAS1 related extracellular matrix 1
chr14_+_94581407 0.07 ENST00000553511.1
ENST00000329597.12
ENST00000554633.5
ENST00000555681.1
ENST00000554276.1
SERPINA5
serpin family A member 5
chr7_+_69967464 0.07 ENST00000664521.1
AUTS2
activator of transcription and developmental regulator AUTS2
chr3_-_155854375 0.07 ENST00000643144.2
ENST00000359479.7
ENST00000646424.1
SLC33A1
solute carrier family 33 member 1
chr7_+_143381907 0.07 ENST00000392910.6
ZYX
zyxin
chr11_-_65381951 0.07 ENST00000526432.5
ENST00000527174.5
SLC25A45
solute carrier family 25 member 45
chr2_-_46915745 0.07 ENST00000649435.1
ENST00000409105.5
ENST00000319466.9
ENST00000409973.5
ENST00000409913.5
MCFD2
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chrX_-_129843388 0.07 ENST00000371064.7
ZDHHC9
zinc finger DHHC-type palmitoyltransferase 9
chrX_-_13938618 0.07 ENST00000454189.6
GPM6B
glycoprotein M6B
chr10_+_17229267 0.07 ENST00000224237.9
VIM
vimentin
chr19_-_7699466 0.07 ENST00000360067.8
FCER2
Fc fragment of IgE receptor II
chr14_+_69484722 0.07 ENST00000322564.9
PLEKHD1
pleckstrin homology and coiled-coil domain containing D1
chr2_-_37671633 0.07 ENST00000295324.4
CDC42EP3
CDC42 effector protein 3
chr1_+_224183262 0.07 ENST00000391877.3
DEGS1
delta 4-desaturase, sphingolipid 1
chr16_+_176659 0.07 ENST00000320868.9
ENST00000397797.1
HBA1
hemoglobin subunit alpha 1
chr15_+_90903288 0.06 ENST00000559717.6
MAN2A2
mannosidase alpha class 2A member 2
chr2_+_108621260 0.06 ENST00000409441.5
LIMS1
LIM zinc finger domain containing 1
chr11_+_34642468 0.06 ENST00000527935.1
EHF
ETS homologous factor
chr16_+_75148478 0.06 ENST00000568079.5
ENST00000570010.6
ENST00000464850.5
ENST00000332307.4
ENST00000393430.6
ZFP1
ZFP1 zinc finger protein
chr2_-_157874976 0.06 ENST00000682025.1
ENST00000683487.1
ENST00000682300.1
ENST00000683441.1
ENST00000684595.1
ENST00000683426.1
ENST00000683820.1
ENST00000263640.7
ACVR1
activin A receptor type 1
chr1_+_154405326 0.06 ENST00000368485.8
IL6R
interleukin 6 receptor
chr6_+_39792993 0.06 ENST00000538976.5
DAAM2
dishevelled associated activator of morphogenesis 2
chr17_-_68601357 0.06 ENST00000592554.2
FAM20A
FAM20A golgi associated secretory pathway pseudokinase
chr5_+_52787899 0.06 ENST00000274311.3
ENST00000282588.7
PELO
ITGA1
pelota mRNA surveillance and ribosome rescue factor
integrin subunit alpha 1
chr6_+_39793008 0.06 ENST00000398904.6
DAAM2
dishevelled associated activator of morphogenesis 2
chr1_-_161223559 0.06 ENST00000469730.2
ENST00000463273.5
ENST00000464492.5
ENST00000367990.7
ENST00000470459.6
ENST00000463812.1
ENST00000468465.5
APOA2
apolipoprotein A2
chr11_+_1157946 0.06 ENST00000621226.2
MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chrX_+_155382095 0.06 ENST00000369505.5
F8A2
coagulation factor VIII associated 2
chr1_+_63367619 0.06 ENST00000263440.6
ALG6
ALG6 alpha-1,3-glucosyltransferase
chr2_+_222671651 0.06 ENST00000446656.4
MOGAT1
monoacylglycerol O-acyltransferase 1
chr19_+_57599874 0.06 ENST00000332854.11
ENST00000597700.6
ENST00000597864.1
ZNF530
zinc finger protein 530
chr6_-_53148822 0.06 ENST00000259803.8
GCM1
glial cells missing transcription factor 1
chr12_-_55727796 0.06 ENST00000550776.5
CD63
CD63 molecule
chr8_+_132919403 0.06 ENST00000519178.5
TG
thyroglobulin
chr7_+_102912983 0.06 ENST00000339431.9
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr11_-_10693616 0.06 ENST00000541483.5
IRAG1
inositol 1,4,5-triphosphate receptor associated 1
chrX_-_155458620 0.06 ENST00000622749.2
F8A3
coagulation factor VIII associated 3
chr16_+_32066065 0.06 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr15_-_77071099 0.06 ENST00000267970.9
ENST00000346495.6
ENST00000424443.7
ENST00000561277.5
TSPAN3
tetraspanin 3
chr1_-_26890237 0.06 ENST00000431781.2
ENST00000374135.9
GPN2
GPN-loop GTPase 2
chr3_+_9749940 0.05 ENST00000302003.11
ENST00000349503.9
ENST00000302036.11
ENST00000344629.12
ENST00000339511.9
OGG1
8-oxoguanine DNA glycosylase
chr7_+_116524984 0.05 ENST00000614113.5
ENST00000393470.1
CAV1
caveolin 1
chr11_+_12110569 0.05 ENST00000683283.1
ENST00000256194.8
MICAL2
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr7_-_5423826 0.05 ENST00000430969.6
TNRC18
trinucleotide repeat containing 18
chr4_-_8071978 0.05 ENST00000514025.5
ABLIM2
actin binding LIM protein family member 2
chr2_-_240682879 0.05 ENST00000407834.4
ENST00000621682.4
AQP12B
aquaporin 12B
chr12_+_94262521 0.05 ENST00000545312.1
PLXNC1
plexin C1
chrX_-_153673678 0.05 ENST00000370150.5
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chrX_+_154886355 0.05 ENST00000610495.2
F8A1
coagulation factor VIII associated 1
chr9_-_136748515 0.05 ENST00000341206.9
LCN6
lipocalin 6
chr12_-_55727828 0.05 ENST00000546939.5
CD63
CD63 molecule
chr17_+_79034185 0.05 ENST00000581774.5
C1QTNF1
C1q and TNF related 1
chr3_+_52316319 0.05 ENST00000420323.7
DNAH1
dynein axonemal heavy chain 1
chr5_-_115544734 0.05 ENST00000274457.5
FEM1C
fem-1 homolog C
chrX_+_47078380 0.05 ENST00000352078.8
RGN
regucalcin
chr2_-_218671975 0.05 ENST00000295704.7
RNF25
ring finger protein 25
chrX_-_153673778 0.05 ENST00000340888.8
PNCK
pregnancy up-regulated nonubiquitous CaM kinase
chr12_+_6535278 0.05 ENST00000396858.5
GAPDH
glyceraldehyde-3-phosphate dehydrogenase
chr2_+_218382265 0.05 ENST00000233202.11
SLC11A1
solute carrier family 11 member 1
chr17_-_7179544 0.05 ENST00000619926.4
ASGR1
asialoglycoprotein receptor 1
chr7_-_7535863 0.05 ENST00000399429.8
COL28A1
collagen type XXVIII alpha 1 chain
chr1_-_93585071 0.05 ENST00000539242.5
BCAR3
BCAR3 adaptor protein, NSP family member
chr19_-_40257045 0.05 ENST00000578615.6
AKT2
AKT serine/threonine kinase 2
chr3_-_58627596 0.05 ENST00000474531.5
ENST00000465970.1
FAM107A
family with sequence similarity 107 member A
chr1_+_64470120 0.05 ENST00000651257.2
CACHD1
cache domain containing 1
chr7_+_116525028 0.05 ENST00000341049.7
CAV1
caveolin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of TLX1_NFIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0061517 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.2 GO:0060611 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.7 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:1903633 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
0.0 0.1 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.4 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.6 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0071486 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.0 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.1 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070701 mucus layer(GO:0070701)
0.1 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.1 GO:0097183 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.0 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035375 zymogen binding(GO:0035375)
0.1 0.2 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0035501 MH1 domain binding(GO:0035501)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0004341 gluconolactonase activity(GO:0004341)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.0 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.0 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions