Project

Epithelial-Mesenchymal Transition, human (Scheel, 2011)

Navigation
Downloads

Results for TP73

Z-value: 0.27

Motif logo

logo of

Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
TP73
ENSG00000078900.15 tumor protein p73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg38_v1_chr1_+_3698027_36980580.677.1e-02Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153615858 0.18 ENST00000476873.5
S100A14
S100 calcium binding protein A14
chr19_+_44777860 0.17 ENST00000341505.4
ENST00000647358.2
CBLC
Cbl proto-oncogene C
chr14_+_75279637 0.15 ENST00000555686.1
ENST00000555672.1
FOS
Fos proto-oncogene, AP-1 transcription factor subunit
chr19_+_35106510 0.13 ENST00000648240.1
ENSG00000285526.1
novel protein
chr14_+_75278820 0.13 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
FOS
Fos proto-oncogene, AP-1 transcription factor subunit
chr10_+_46375645 0.13 ENST00000622769.4
ANXA8L1
annexin A8 like 1
chr10_+_46375619 0.12 ENST00000584982.7
ENST00000613703.4
ANXA8L1
annexin A8 like 1
chr17_+_75754618 0.11 ENST00000584939.1
ITGB4
integrin subunit beta 4
chr15_+_40844018 0.11 ENST00000344051.8
ENST00000562057.6
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr3_+_136957948 0.10 ENST00000329582.9
IL20RB
interleukin 20 receptor subunit beta
chr11_+_60429595 0.10 ENST00000528905.1
ENST00000528093.1
MS4A5
membrane spanning 4-domains A5
chr1_-_204190324 0.09 ENST00000638118.1
REN
renin
chr3_-_69386079 0.09 ENST00000398540.8
FRMD4B
FERM domain containing 4B
chr12_-_56488153 0.08 ENST00000311966.9
GLS2
glutaminase 2
chr19_-_291132 0.08 ENST00000327790.7
PLPP2
phospholipid phosphatase 2
chr6_+_36676455 0.07 ENST00000615513.4
CDKN1A
cyclin dependent kinase inhibitor 1A
chr6_+_36676489 0.07 ENST00000448526.6
CDKN1A
cyclin dependent kinase inhibitor 1A
chr11_+_60429567 0.07 ENST00000300190.7
MS4A5
membrane spanning 4-domains A5
chr12_-_6635938 0.07 ENST00000329858.9
LPAR5
lysophosphatidic acid receptor 5
chr3_+_50205254 0.07 ENST00000614032.5
ENST00000445096.5
SLC38A3
solute carrier family 38 member 3
chr2_+_95274439 0.07 ENST00000317620.14
ENST00000403131.6
ENST00000317668.8
PROM2
prominin 2
chr10_-_103452356 0.06 ENST00000260743.10
CALHM2
calcium homeostasis modulator family member 2
chr10_+_46375721 0.06 ENST00000616785.1
ENST00000611655.1
ENST00000619162.5
ENSG00000285402.1
ANXA8L1
novel transcript
annexin A8 like 1
chr10_-_103452384 0.06 ENST00000369788.7
CALHM2
calcium homeostasis modulator family member 2
chr9_+_35673917 0.06 ENST00000617161.1
ENST00000378357.9
CA9
carbonic anhydrase 9
chr3_-_185821092 0.05 ENST00000421047.3
IGF2BP2
insulin like growth factor 2 mRNA binding protein 2
chr18_-_55586092 0.05 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
TCF4
transcription factor 4
chr18_-_55585773 0.05 ENST00000563824.5
ENST00000626425.2
ENST00000566514.5
ENST00000568673.5
ENST00000562847.5
ENST00000568147.5
TCF4
transcription factor 4
chr17_-_44123628 0.05 ENST00000587135.1
ENST00000225983.10
ENST00000682912.1
ENST00000588703.5
HDAC5
histone deacetylase 5
chr6_-_46735351 0.04 ENST00000274793.12
PLA2G7
phospholipase A2 group VII
chr1_+_64745089 0.04 ENST00000294428.7
ENST00000371072.8
RAVER2
ribonucleoprotein, PTB binding 2
chr3_+_44976236 0.04 ENST00000265564.8
EXOSC7
exosome component 7
chr2_+_74002685 0.04 ENST00000305799.8
TET3
tet methylcytosine dioxygenase 3
chr12_+_49295138 0.04 ENST00000257860.9
PRPH
peripherin
chr20_-_54173516 0.03 ENST00000395955.7
CYP24A1
cytochrome P450 family 24 subfamily A member 1
chr12_-_31729010 0.03 ENST00000537562.5
ENST00000537960.5
ENST00000281471.11
ENST00000536761.5
ENST00000542781.5
ENST00000457428.6
AMN1
antagonist of mitotic exit network 1 homolog
chr4_+_38664189 0.03 ENST00000514033.1
ENST00000261438.10
KLF3
Kruppel like factor 3
chr2_+_176116768 0.03 ENST00000249501.5
HOXD10
homeobox D10
chr19_+_43533384 0.03 ENST00000601282.1
ZNF575
zinc finger protein 575
chr17_+_39200507 0.03 ENST00000678573.1
RPL19
ribosomal protein L19
chr6_-_46735693 0.03 ENST00000537365.1
PLA2G7
phospholipase A2 group VII
chr19_-_35490456 0.03 ENST00000338897.4
ENST00000484218.6
KRTDAP
keratinocyte differentiation associated protein
chr16_+_30923565 0.03 ENST00000338343.10
FBXL19
F-box and leucine rich repeat protein 19
chr16_+_2019777 0.03 ENST00000566435.4
NPW
neuropeptide W
chrX_+_153642473 0.03 ENST00000370167.8
DUSP9
dual specificity phosphatase 9
chr17_+_39200334 0.03 ENST00000579260.5
ENST00000582193.5
RPL19
ribosomal protein L19
chr14_-_100569780 0.03 ENST00000355173.7
BEGAIN
brain enriched guanylate kinase associated
chr18_+_13277351 0.03 ENST00000679091.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr17_+_39200275 0.03 ENST00000225430.9
RPL19
ribosomal protein L19
chr11_-_236821 0.03 ENST00000529382.5
ENST00000528469.1
SIRT3
sirtuin 3
chr14_+_22086401 0.03 ENST00000390451.2
TRAV23DV6
T cell receptor alpha variable 23/delta variable 6
chr16_+_56191476 0.03 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr19_+_19516216 0.03 ENST00000507754.9
ENST00000503283.5
ENST00000428459.6
ENST00000555938.1
NDUFA13
ENSG00000258674.5
NADH:ubiquinone oxidoreductase subunit A13
novel protein
chr2_+_219572304 0.03 ENST00000243786.3
INHA
inhibin subunit alpha
chr17_+_39200302 0.02 ENST00000579374.5
RPL19
ribosomal protein L19
chr17_-_40867200 0.02 ENST00000647902.1
ENST00000251643.5
KRT12
keratin 12
chr16_+_74999003 0.02 ENST00000335325.9
ENST00000320619.10
ZNRF1
zinc and ring finger 1
chr17_+_21288029 0.02 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
MAP2K3
mitogen-activated protein kinase kinase 3
chr17_+_7888783 0.02 ENST00000330494.12
ENST00000358181.8
CHD3
chromodomain helicase DNA binding protein 3
chr19_+_41860236 0.02 ENST00000601492.5
ENST00000600467.6
ENST00000598742.6
ENST00000221975.6
ENST00000598261.2
RPS19
ribosomal protein S19
chr2_-_26641363 0.02 ENST00000288861.5
CIB4
calcium and integrin binding family member 4
chr16_-_8797624 0.02 ENST00000333050.7
TMEM186
transmembrane protein 186
chr9_+_36169382 0.02 ENST00000335119.4
CCIN
calicin
chr19_-_38735405 0.02 ENST00000597987.5
ENST00000595177.1
CAPN12
calpain 12
chr17_-_76027296 0.02 ENST00000301607.8
EVPL
envoplakin
chr11_+_66466745 0.02 ENST00000349459.10
ENST00000320740.12
ENST00000524466.5
ENST00000526296.5
PELI3
pellino E3 ubiquitin protein ligase family member 3
chr4_+_6716131 0.02 ENST00000320776.5
BLOC1S4
biogenesis of lysosomal organelles complex 1 subunit 4
chr14_+_103385450 0.02 ENST00000416682.6
MARK3
microtubule affinity regulating kinase 3
chr22_-_37580075 0.02 ENST00000215886.6
LGALS2
galectin 2
chr8_+_119873710 0.02 ENST00000523492.5
ENST00000286234.6
DEPTOR
DEP domain containing MTOR interacting protein
chr12_+_82358496 0.02 ENST00000248306.8
ENST00000548200.5
METTL25
methyltransferase like 25
chr2_+_158968608 0.02 ENST00000263635.8
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr16_-_636270 0.01 ENST00000397665.6
ENST00000397666.6
ENST00000301686.13
ENST00000338401.8
ENST00000397664.8
ENST00000568830.1
ENST00000614890.4
METTL26
methyltransferase like 26
chr4_-_20984011 0.01 ENST00000382149.9
KCNIP4
potassium voltage-gated channel interacting protein 4
chr19_+_41350911 0.01 ENST00000539627.5
TMEM91
transmembrane protein 91
chr2_+_89884740 0.01 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr10_-_103479240 0.01 ENST00000369783.4
CALHM3
calcium homeostasis modulator 3
chr14_+_103385506 0.01 ENST00000303622.13
MARK3
microtubule affinity regulating kinase 3
chr10_+_68901258 0.01 ENST00000373585.8
DDX50
DExD-box helicase 50
chr20_-_63572455 0.01 ENST00000467148.1
HELZ2
helicase with zinc finger 2
chr20_-_59940289 0.01 ENST00000370996.5
PPP1R3D
protein phosphatase 1 regulatory subunit 3D
chr19_+_43716095 0.01 ENST00000596627.1
IRGC
immunity related GTPase cinema
chr1_+_26159071 0.01 ENST00000374268.5
FAM110D
family with sequence similarity 110 member D
chr14_+_103385374 0.01 ENST00000678179.1
ENST00000676938.1
ENST00000678619.1
ENST00000440884.7
ENST00000560417.6
ENST00000679330.1
ENST00000556744.2
ENST00000676897.1
ENST00000677560.1
ENST00000561314.6
ENST00000677829.1
ENST00000677133.1
ENST00000676645.1
ENST00000678175.1
ENST00000429436.7
ENST00000677360.1
ENST00000678237.1
ENST00000677347.1
ENST00000677432.1
MARK3
microtubule affinity regulating kinase 3
chr7_-_128405930 0.01 ENST00000470772.5
ENST00000480861.5
ENST00000496200.5
IMPDH1
inosine monophosphate dehydrogenase 1
chr20_-_54173976 0.01 ENST00000216862.8
CYP24A1
cytochrome P450 family 24 subfamily A member 1
chr10_-_77926724 0.01 ENST00000372391.7
DLG5
discs large MAGUK scaffold protein 5
chr1_+_156815633 0.01 ENST00000392302.7
ENST00000674537.1
NTRK1
neurotrophic receptor tyrosine kinase 1
chr9_-_135499846 0.01 ENST00000429260.7
C9orf116
chromosome 9 open reading frame 116
chr11_+_237016 0.01 ENST00000352303.9
PSMD13
proteasome 26S subunit, non-ATPase 13
chr17_-_82101850 0.01 ENST00000583053.1
CCDC57
coiled-coil domain containing 57
chr17_-_5123102 0.01 ENST00000250076.7
ZNF232
zinc finger protein 232
chr2_+_69741974 0.01 ENST00000409920.5
ANXA4
annexin A4
chr11_+_236957 0.01 ENST00000532097.6
ENST00000431206.6
ENST00000528906.5
ENST00000621534.4
PSMD13
proteasome 26S subunit, non-ATPase 13
chrX_-_132094263 0.01 ENST00000370879.5
FRMD7
FERM domain containing 7
chr10_+_62804710 0.01 ENST00000373783.3
ADO
2-aminoethanethiol dioxygenase
chr5_+_126423122 0.01 ENST00000515200.5
GRAMD2B
GRAM domain containing 2B
chr9_+_84669760 0.01 ENST00000304053.10
NTRK2
neurotrophic receptor tyrosine kinase 2
chr5_+_126423176 0.01 ENST00000542322.5
ENST00000544396.5
GRAMD2B
GRAM domain containing 2B
chr16_+_56191728 0.01 ENST00000638705.1
ENST00000262494.12
GNAO1
G protein subunit alpha o1
chr16_+_8797813 0.01 ENST00000268261.9
ENST00000569958.5
PMM2
phosphomannomutase 2
chr5_+_126423363 0.01 ENST00000285689.8
GRAMD2B
GRAM domain containing 2B
chrX_+_131058340 0.01 ENST00000276211.10
ENST00000370922.5
ARHGAP36
Rho GTPase activating protein 36
chr1_+_109539865 0.01 ENST00000618721.4
ENST00000527748.5
ENST00000616874.1
GPR61
G protein-coupled receptor 61
chr3_+_48440246 0.01 ENST00000438607.2
TMA7
translation machinery associated 7 homolog
chr3_-_48898813 0.01 ENST00000319017.5
ENST00000430379.5
SLC25A20
solute carrier family 25 member 20
chr17_-_76027212 0.01 ENST00000586740.1
EVPL
envoplakin
chr2_-_27134611 0.01 ENST00000406567.7
ENST00000260643.7
PREB
prolactin regulatory element binding
chr19_+_12995554 0.01 ENST00000397661.6
NFIX
nuclear factor I X
chr18_-_4455257 0.01 ENST00000581527.5
DLGAP1
DLG associated protein 1
chr3_+_42160160 0.01 ENST00000341421.7
ENST00000396175.5
TRAK1
trafficking kinesin protein 1
chr4_+_105710809 0.01 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
GSTCD
glutathione S-transferase C-terminal domain containing
chr20_+_59940362 0.01 ENST00000360816.8
FAM217B
family with sequence similarity 217 member B
chrX_-_139642518 0.01 ENST00000370573.8
ENST00000338585.6
MCF2
MCF.2 cell line derived transforming sequence
chr16_+_89918855 0.01 ENST00000555147.2
MC1R
melanocortin 1 receptor
chr1_-_203086001 0.01 ENST00000241651.5
MYOG
myogenin
chr19_+_44751251 0.00 ENST00000444487.1
BCL3
BCL3 transcription coactivator
chr19_+_17215716 0.00 ENST00000593597.1
USE1
unconventional SNARE in the ER 1
chr12_-_82358380 0.00 ENST00000256151.8
ENST00000552377.5
CCDC59
coiled-coil domain containing 59
chr1_+_16043776 0.00 ENST00000375679.9
CLCNKB
chloride voltage-gated channel Kb
chr6_+_31547560 0.00 ENST00000376148.9
ENST00000376145.8
NFKBIL1
NFKB inhibitor like 1
chr12_-_116881431 0.00 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein
chr14_-_25050111 0.00 ENST00000323944.9
STXBP6
syntaxin binding protein 6
chr1_+_16043736 0.00 ENST00000619181.4
CLCNKB
chloride voltage-gated channel Kb
chr14_-_25049889 0.00 ENST00000419632.6
ENST00000396700.5
STXBP6
syntaxin binding protein 6
chr8_+_144504131 0.00 ENST00000394955.3
GPT
glutamic--pyruvic transaminase
chr19_+_43716070 0.00 ENST00000244314.6
IRGC
immunity related GTPase cinema
chr2_-_38602626 0.00 ENST00000378915.7
HNRNPLL
heterogeneous nuclear ribonucleoprotein L like
chr14_-_24576240 0.00 ENST00000216336.3
CTSG
cathepsin G
chr19_+_41114430 0.00 ENST00000331105.7
CYP2F1
cytochrome P450 family 2 subfamily F member 1
chr2_+_127535746 0.00 ENST00000428314.5
ENST00000409816.7
MYO7B
myosin VIIB

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0015817 histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.0 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.0 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.0 GO:0042369 vitamin D catabolic process(GO:0042369)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0044393 microspike(GO:0044393)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors