Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
ENSG00000184937.16 | WT1 transcription factor | |
ENSG00000188786.10 | metal regulatory transcription factor 1 | |
ENSG00000160685.13 | zinc finger and BTB domain containing 7B |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
WT1 | hg38_v1_chr11_-_32430811_32430817, hg38_v1_chr11_-_32435557_32435578 | 0.66 | 7.7e-02 | Click! |
MTF1 | hg38_v1_chr1_-_37859583_37859609 | -0.23 | 5.8e-01 | Click! |
ZBTB7B | hg38_v1_chr1_+_155002630_155002689 | 0.08 | 8.5e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 10.1 | GO:0051823 | regulation of synapse structural plasticity(GO:0051823) |
1.4 | 5.7 | GO:0032597 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
0.0 | 4.9 | GO:0070268 | cornification(GO:0070268) |
0.1 | 4.8 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
0.8 | 3.9 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
0.2 | 3.6 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.4 | 3.5 | GO:2000620 | innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620) |
0.1 | 3.4 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.1 | 3.3 | GO:0007172 | signal complex assembly(GO:0007172) |
0.5 | 3.1 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 11.8 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.1 | 8.8 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
0.2 | 5.5 | GO:0030057 | desmosome(GO:0030057) |
0.2 | 5.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.1 | 3.9 | GO:0005922 | connexon complex(GO:0005922) |
0.2 | 3.8 | GO:0031932 | TORC2 complex(GO:0031932) |
0.1 | 3.5 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.1 | 3.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 3.1 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 2.9 | GO:0005861 | troponin complex(GO:0005861) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 6.5 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.1 | 6.3 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 4.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.8 | 3.9 | GO:0004122 | cystathionine beta-synthase activity(GO:0004122) |
0.1 | 3.8 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.1 | 3.6 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.3 | 3.5 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.2 | 3.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 3.4 | GO:0005112 | Notch binding(GO:0005112) |
0.5 | 3.2 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 9.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
0.1 | 5.4 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
0.1 | 4.6 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.1 | 4.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 4.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 3.2 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 2.9 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.1 | 2.7 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
0.0 | 2.5 | PID P73PATHWAY | p73 transcription factor network |
0.0 | 2.4 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 9.6 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
0.2 | 3.9 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
0.1 | 3.6 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.1 | 3.3 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 3.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.2 | 3.1 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
0.1 | 3.0 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.0 | 2.9 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.1 | 2.8 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
0.1 | 2.8 | REACTOME KINESINS | Genes involved in Kinesins |