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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZBTB16

Z-value: 1.12

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Transcription factors associated with ZBTB16

Gene Symbol Gene ID Gene Info
ENSG00000109906.15 zinc finger and BTB domain containing 16

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB16hg38_v1_chr11_+_114059755_114059881,
hg38_v1_chr11_+_114060204_114060247
0.866.7e-03Click!

Activity profile of ZBTB16 motif

Sorted Z-values of ZBTB16 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91146195 1.94 ENST00000548218.1
decorin
chr2_+_232662733 1.35 ENST00000410095.5
ENST00000611312.1
EF-hand domain family member D1
chr1_+_170663917 1.21 ENST00000497230.2
paired related homeobox 1
chr9_-_92482350 1.19 ENST00000375543.2
asporin
chr2_-_187554351 1.00 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr3_+_148697784 1.00 ENST00000497524.5
ENST00000418473.7
ENST00000349243.8
ENST00000404754.2
angiotensin II receptor type 1
chr18_-_54959391 0.88 ENST00000591504.6
coiled-coil domain containing 68
chr6_+_32844789 0.85 ENST00000414474.5
proteasome 20S subunit beta 9
chr14_+_21990357 0.82 ENST00000390444.1
T cell receptor alpha variable 16
chr4_-_158173042 0.82 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr9_-_92482499 0.77 ENST00000375544.7
asporin
chr4_-_158173004 0.74 ENST00000585682.6
golgi associated kinase 1B
chr21_-_30480364 0.74 ENST00000390689.3
keratin associated protein 19-1
chr6_+_135851681 0.72 ENST00000308191.11
phosphodiesterase 7B
chr10_+_102854251 0.68 ENST00000339834.10
ENST00000369883.3
BLOC-1 related complex subunit 7
chr4_+_73481737 0.68 ENST00000226355.5
afamin
chr5_+_68290637 0.68 ENST00000336483.9
phosphoinositide-3-kinase regulatory subunit 1
chr20_-_18497218 0.60 ENST00000337227.9
RB binding protein 9, serine hydrolase
chr11_-_70826887 0.58 ENST00000656230.1
SH3 and multiple ankyrin repeat domains 2
chr10_+_110005804 0.55 ENST00000360162.7
adducin 3
chr9_+_76459152 0.55 ENST00000444201.6
ENST00000376730.5
glucosaminyl (N-acetyl) transferase 1
chr7_+_7566866 0.54 ENST00000405785.5
ENST00000340080.9
ENST00000433635.1
meiosis regulator for oocyte development
chr12_+_15546344 0.53 ENST00000674388.1
ENST00000542557.5
ENST00000445537.6
ENST00000544244.5
ENST00000442921.7
protein tyrosine phosphatase receptor type O
chr10_+_8054808 0.52 ENST00000346208.4
GATA binding protein 3
chr4_+_70242583 0.50 ENST00000304954.3
casein kappa
chr17_-_445939 0.47 ENST00000329099.4
refilin B
chr7_-_93148345 0.45 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr10_+_80131660 0.45 ENST00000372270.6
placenta associated 9
chr22_+_37807891 0.43 ENST00000323205.10
ENST00000445195.5
ENST00000248924.11
glycine C-acetyltransferase
chr10_+_8054668 0.43 ENST00000379328.9
GATA binding protein 3
chr4_-_82848843 0.43 ENST00000511338.1
SEC31 homolog A, COPII coat complex component
chr19_+_14583076 0.39 ENST00000547437.5
ENST00000417570.6
C-type lectin domain containing 17A
chr15_+_75336018 0.39 ENST00000567195.5
COMM domain containing 4
chr10_-_28334439 0.39 ENST00000441595.2
membrane palmitoylated protein 7
chr14_-_105242605 0.38 ENST00000549655.5
BRF1 RNA polymerase III transcription initiation factor subunit
chr5_+_141330494 0.37 ENST00000517417.3
ENST00000378105.4
protocadherin gamma subfamily A, 1
chr15_+_75336078 0.37 ENST00000567377.5
ENST00000562789.5
ENST00000568301.1
COMM domain containing 4
chr2_-_210303608 0.37 ENST00000341685.8
myosin light chain 1
chr15_+_75336053 0.35 ENST00000564815.5
ENST00000338995.10
ENST00000267935.13
COMM domain containing 4
chrX_-_47659128 0.35 ENST00000333119.7
ENST00000335890.3
ubiquitously expressed prefoldin like chaperone
chr1_+_35869750 0.35 ENST00000373206.5
argonaute RISC component 1
chr15_-_52652031 0.35 ENST00000546305.6
family with sequence similarity 214 member A
chr1_+_178341445 0.34 ENST00000462775.5
RAS protein activator like 2
chr11_-_66677748 0.31 ENST00000525754.5
ENST00000531969.5
ENST00000524637.1
ENST00000531036.2
ENST00000310046.9
RNA binding motif protein 4B
chr8_+_12104389 0.31 ENST00000400085.7
zinc finger protein 705D
chr3_-_15341368 0.30 ENST00000408919.7
SH3 domain binding protein 5
chr21_+_39445824 0.29 ENST00000380637.7
ENST00000380634.5
ENST00000458295.5
ENST00000440288.6
ENST00000380631.5
SH3 domain binding glutamate rich protein
chr10_+_122910605 0.29 ENST00000368894.2
family with sequence similarity 24 member A
chr6_+_132570322 0.29 ENST00000275198.1
trace amine associated receptor 6
chr4_+_85778681 0.29 ENST00000395183.6
Rho GTPase activating protein 24
chr6_+_25962792 0.29 ENST00000357085.5
tripartite motif containing 38
chr9_-_128191878 0.28 ENST00000538431.5
CDKN1A interacting zinc finger protein 1
chr12_+_53442555 0.28 ENST00000549135.1
proline rich 13
chr1_+_156126160 0.27 ENST00000448611.6
ENST00000368297.5
lamin A/C
chr3_-_138594319 0.27 ENST00000489254.5
ENST00000474781.5
ENST00000462419.5
centrosomal protein 70
chr3_-_138594129 0.27 ENST00000485115.1
ENST00000484888.5
ENST00000468900.5
ENST00000481834.5
ENST00000264982.8
centrosomal protein 70
chr22_-_35840577 0.27 ENST00000405409.6
RNA binding fox-1 homolog 2
chr6_-_34671918 0.26 ENST00000374021.1
inflammation and lipid regulator with UBA-like and NBR1-like domains
chr3_+_40477107 0.26 ENST00000314686.9
ENST00000447116.6
ENST00000429348.6
ENST00000432264.4
ENST00000456778.5
zinc finger protein 619
chr7_-_108130349 0.25 ENST00000205386.8
ENST00000418464.1
ENST00000388781.8
laminin subunit beta 4
chrX_+_12867064 0.25 ENST00000380659.4
toll like receptor 7
chr19_+_20776292 0.25 ENST00000360204.5
ENST00000344519.10
ENST00000594534.5
zinc finger protein 66
chr7_+_28685968 0.24 ENST00000396298.6
cAMP responsive element binding protein 5
chr19_-_58150772 0.24 ENST00000597186.5
ENST00000598312.6
zinc finger protein 329
chr1_-_15809348 0.24 ENST00000483273.2
ubiquinol-cytochrome c reductase hinge protein like
chr21_-_29019314 0.24 ENST00000493196.2
RWD domain containing 2B
chr12_+_18262730 0.24 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr13_-_100588731 0.24 ENST00000471912.1
ENST00000683975.1
gamma-glutamylamine cyclotransferase
chr14_-_89412025 0.24 ENST00000553840.5
ENST00000556916.5
forkhead box N3
chr15_-_55270383 0.24 ENST00000396307.6
RAB27A, member RAS oncogene family
chr3_-_165837412 0.24 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chrX_+_72181676 0.23 ENST00000218432.10
ENST00000664196.1
ENST00000423432.6
peptidylprolyl cis/trans isomerase, NIMA-interacting 4
chr1_+_33081145 0.23 ENST00000294517.11
ENST00000373443.7
antizyme inhibitor 2
chr3_+_183635605 0.22 ENST00000493074.1
ENST00000437402.5
ENST00000454495.6
ENST00000473045.5
ENST00000468101.5
ENST00000427201.2
ENST00000482138.1
ENST00000454652.6
ENST00000242810.11
kelch like family member 24
chr22_-_35840218 0.22 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr10_+_5094405 0.22 ENST00000380554.5
aldo-keto reductase family 1 member C3
chr12_+_21131187 0.22 ENST00000256958.3
solute carrier organic anion transporter family member 1B1
chr16_+_22490337 0.22 ENST00000415833.6
nuclear pore complex interacting protein family member B5
chr1_+_210328244 0.21 ENST00000541565.5
ENST00000413764.6
hedgehog acyltransferase
chr1_+_201648136 0.21 ENST00000367296.8
neuron navigator 1
chr17_+_48831021 0.20 ENST00000509507.5
ENST00000448105.6
ENST00000570513.5
ENST00000509415.5
ENST00000513119.5
ENST00000416445.6
ENST00000508679.5
ENST00000258947.8
ENST00000505071.5
calcium binding and coiled-coil domain 2
chr12_+_10307950 0.20 ENST00000543420.5
ENST00000543777.5
killer cell lectin like receptor D1
chr5_+_161850597 0.20 ENST00000634335.1
ENST00000635880.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr11_+_120385286 0.20 ENST00000532993.5
Rho guanine nucleotide exchange factor 12
chr1_-_246193727 0.20 ENST00000391836.3
SET and MYND domain containing 3
chr15_+_41286011 0.19 ENST00000661438.1
novel protein
chr4_-_139302460 0.19 ENST00000394223.2
ENST00000676245.1
NADH:ubiquinone oxidoreductase subunit C1
chr12_+_47773195 0.18 ENST00000442218.3
solute carrier family 48 member 1
chr3_-_71493500 0.18 ENST00000648380.1
ENST00000650295.1
forkhead box P1
chr2_+_241350087 0.18 ENST00000451310.1
septin 2
chr1_+_13171848 0.18 ENST00000415919.3
PRAME family member 9
chr10_-_99235783 0.18 ENST00000370546.5
ENST00000614306.1
heparanase 2 (inactive)
chr19_+_35748549 0.18 ENST00000301159.14
lin-37 DREAM MuvB core complex component
chr9_-_15472732 0.18 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr10_-_99235846 0.17 ENST00000370552.8
ENST00000370549.5
ENST00000628193.2
heparanase 2 (inactive)
chr11_-_13496018 0.17 ENST00000529816.1
parathyroid hormone
chr19_+_43575801 0.17 ENST00000599207.6
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr2_+_131105296 0.17 ENST00000628582.2
pleckstrin homology domain containing B2
chr12_+_26011713 0.17 ENST00000542004.5
Ras association domain family member 8
chr3_-_165078480 0.17 ENST00000264382.8
sucrase-isomaltase
chr17_-_9575811 0.17 ENST00000306357.9
ENST00000574431.5
syntaxin 8
chr4_-_48080172 0.17 ENST00000507351.1
TXK tyrosine kinase
chr6_+_37929959 0.17 ENST00000373389.5
zinc finger AN1-type containing 3
chr1_+_12791397 0.16 ENST00000332296.7
PRAME family member 1
chr1_+_12857086 0.16 ENST00000240189.2
PRAME family member 2
chr19_+_47745534 0.16 ENST00000246802.10
NOP53 ribosome biogenesis factor
chr3_-_187139477 0.16 ENST00000455270.5
ENST00000296277.9
ribosomal protein L39 like
chr22_+_28772664 0.16 ENST00000448492.6
ENST00000421503.6
ENST00000249064.9
ENST00000444523.1
coiled-coil domain containing 117
chr5_+_76875177 0.16 ENST00000613039.1
S100 calcium binding protein Z
chr22_+_23856703 0.15 ENST00000345044.10
solute carrier family 2 member 11
chr7_-_138627444 0.15 ENST00000463557.1
SVOP like
chr4_-_139302516 0.15 ENST00000394228.5
ENST00000539387.5
NADH:ubiquinone oxidoreductase subunit C1
chr16_-_4474549 0.15 ENST00000404295.7
ENST00000283429.11
ENST00000574425.5
NmrA like redox sensor 1
chr18_-_50825373 0.15 ENST00000588444.5
ENST00000256425.6
ENST00000428869.6
maestro
chr2_-_227379297 0.15 ENST00000304568.4
transmembrane 4 L six family member 20
chr17_-_59151794 0.15 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr19_+_24087179 0.15 ENST00000339642.10
ENST00000357002.5
zinc finger protein 254
chr19_+_35651245 0.14 ENST00000590618.1
cytochrome c oxidase subunit 6B1
chr9_+_5890872 0.14 ENST00000381477.8
ENST00000381476.5
ENST00000381471.1
melan-A
chr3_+_184812138 0.14 ENST00000287546.8
VPS8 subunit of CORVET complex
chr1_-_114749900 0.14 ENST00000438362.6
cold shock domain containing E1
chr19_-_13506408 0.14 ENST00000637736.1
ENST00000637432.1
ENST00000638029.1
ENST00000360228.11
ENST00000638009.2
ENST00000637769.1
ENST00000635895.1
calcium voltage-gated channel subunit alpha1 A
chr12_+_133080875 0.13 ENST00000412146.6
ENST00000544426.5
ENST00000355557.7
ENST00000319849.7
ENST00000440550.6
zinc finger protein 140
chr20_-_45670239 0.13 ENST00000324384.4
ENST00000356562.6
WAP four-disulfide core domain 11
chr3_+_184812159 0.13 ENST00000625842.3
ENST00000436792.6
ENST00000446204.6
ENST00000422105.5
VPS8 subunit of CORVET complex
chr19_-_45691771 0.13 ENST00000588599.5
ENST00000585392.2
ENST00000590212.1
ENST00000587367.5
ENST00000391932.7
ENST00000342669.8
small nuclear ribonucleoprotein D2 polypeptide
chr12_+_10307818 0.13 ENST00000350274.9
ENST00000336164.9
killer cell lectin like receptor D1
chr1_+_198638968 0.13 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr5_+_69565122 0.12 ENST00000507595.1
GTF2H2 family member C
chr5_-_88731827 0.12 ENST00000627170.2
myocyte enhancer factor 2C
chr18_+_616711 0.12 ENST00000579494.1
clusterin like 1
chr12_-_10909562 0.12 ENST00000390677.2
taste 2 receptor member 13
chr5_-_56116946 0.11 ENST00000434982.2
ankyrin repeat domain 55
chr3_+_150408314 0.11 ENST00000361875.7
TSC22 domain family member 2
chr7_+_134779663 0.11 ENST00000361901.6
caldesmon 1
chr5_+_160421847 0.11 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1 regulator of sister chromatid separation, securin
chr6_+_42782020 0.11 ENST00000314073.9
BRD4 interacting chromatin remodeling complex associated protein like
chr16_+_81037187 0.11 ENST00000564241.5
ENST00000565237.1
ATM interactor
chr20_-_33004307 0.10 ENST00000420875.5
ENST00000375519.2
ENST00000375523.7
ENST00000356173.8
Sad1 and UNC84 domain containing 5
chr19_-_19821704 0.10 ENST00000443905.6
ENST00000590766.5
ENST00000587452.5
ENST00000545006.1
ENST00000590319.1
ENST00000587461.5
ENST00000450683.6
ENST00000540806.7
ENST00000590274.1
zinc finger protein 506
novel transcript
chrX_-_49233309 0.10 ENST00000376251.5
ENST00000323022.10
ENST00000376265.2
calcium voltage-gated channel subunit alpha1 F
chr18_+_616672 0.10 ENST00000338387.11
clusterin like 1
chr1_+_247549002 0.10 ENST00000366488.5
germinal center associated signaling and motility like
chr22_+_24011192 0.09 ENST00000454754.5
ENST00000263119.10
ENST00000617531.4
calcineurin binding protein 1
chrX_+_88749318 0.09 ENST00000614120.1
CPX chromosome region candidate 1
chr18_+_41955186 0.08 ENST00000639914.1
ENST00000262039.9
ENST00000398870.7
ENST00000586545.5
ENST00000585528.5
phosphatidylinositol 3-kinase catalytic subunit type 3
chr11_-_95910665 0.08 ENST00000674610.1
ENST00000675660.1
myotubularin related protein 2
chr22_-_30505650 0.08 ENST00000381982.3
ENST00000255858.12
SEC14 like lipid binding 4
chr18_+_36129888 0.08 ENST00000351393.10
ENST00000442325.6
ENST00000423854.6
ENST00000358232.11
ENST00000350494.10
ENST00000542824.5
elongator acetyltransferase complex subunit 2
chr19_+_57128643 0.08 ENST00000598197.1
ubiquitin specific peptidase 29
chr2_+_131105326 0.08 ENST00000438882.6
ENST00000404460.5
pleckstrin homology domain containing B2
chr7_+_1688119 0.08 ENST00000424383.4
extracellular leucine rich repeat and fibronectin type III domain containing 1
chr19_+_24087147 0.07 ENST00000611359.3
ENST00000616028.2
zinc finger protein 254
chr7_+_120951116 0.07 ENST00000431467.1
inhibitor of growth family member 3
chr3_+_172754457 0.07 ENST00000441497.6
epithelial cell transforming 2
chr12_+_133181409 0.07 ENST00000416488.5
ENST00000228289.9
ENST00000541211.6
ENST00000536435.7
ENST00000500625.7
ENST00000539248.6
ENST00000542711.6
ENST00000536899.6
ENST00000542986.6
ENST00000611984.4
ENST00000541975.2
zinc finger protein 268
chr15_+_81196871 0.07 ENST00000559383.5
ENST00000394660.6
ENST00000683961.1
interleukin 16
chrX_-_24027186 0.07 ENST00000328046.8
kelch like family member 15
chr20_+_32819942 0.07 ENST00000375571.6
microtubule associated protein RP/EB family member 1
chr11_-_95910824 0.06 ENST00000674528.1
ENST00000675477.1
ENST00000675636.1
myotubularin related protein 2
chr12_-_7503744 0.06 ENST00000396620.7
ENST00000432237.3
CD163 molecule
chr11_-_124313949 0.06 ENST00000641015.1
olfactory receptor family 8 subfamily D member 1
chr12_-_121669646 0.06 ENST00000355329.7
MORN repeat containing 3
chr11_-_95910748 0.06 ENST00000675933.1
myotubularin related protein 2
chr19_+_4153616 0.06 ENST00000078445.7
ENST00000595923.5
ENST00000602257.5
ENST00000602147.1
cAMP responsive element binding protein 3 like 3
chr1_+_241532370 0.05 ENST00000366559.9
ENST00000366557.8
kynurenine 3-monooxygenase
chr6_-_137044269 0.05 ENST00000635289.1
ENST00000541547.5
interleukin 20 receptor subunit alpha
chr12_-_7503841 0.05 ENST00000359156.8
CD163 molecule
chr9_-_7799752 0.05 ENST00000358227.5
distal membrane arm assembly complex 1
chr9_-_21240002 0.05 ENST00000380222.4
interferon alpha 14
chr5_-_175968280 0.04 ENST00000513482.1
ENST00000265097.9
ENST00000628318.2
THO complex 3
chr19_-_22215746 0.04 ENST00000650058.1
zinc finger protein 676
chr4_+_36281591 0.04 ENST00000639862.2
ENST00000357504.7
death domain containing 1
chr17_-_41160746 0.04 ENST00000390661.5
keratin associated protein 4-4
chr12_-_53207241 0.04 ENST00000267082.10
ENST00000549086.2
integrin subunit beta 7
chr19_-_23687163 0.04 ENST00000601010.5
ENST00000601935.5
ENST00000600313.5
ENST00000596211.5
ENST00000359788.9
ENST00000599168.1
zinc finger protein 675
chr7_+_106865474 0.03 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr2_-_212124901 0.03 ENST00000402597.6
erb-b2 receptor tyrosine kinase 4
chr4_+_37960397 0.03 ENST00000504686.2
pituitary tumor-transforming 2
chr13_+_75549734 0.03 ENST00000563635.5
ENST00000377595.8
novel transcript
ubiquitin C-terminal hydrolase L3
chr1_+_110451132 0.03 ENST00000271331.4
prokineticin 1
chr10_+_113125536 0.03 ENST00000349937.7
transcription factor 7 like 2
chr10_-_67838019 0.03 ENST00000483798.6
DnaJ heat shock protein family (Hsp40) member C12
chr12_-_53207271 0.03 ENST00000552972.5
ENST00000422257.7
integrin subunit beta 7
chr2_-_177263800 0.03 ENST00000397063.8
ENST00000421929.5
nuclear factor, erythroid 2 like 2
chrX_-_120878924 0.02 ENST00000613352.1
novel protein similar to cancer/testis antigen family 47, member A12 (CT47A12)
chr7_-_50093204 0.02 ENST00000419417.5
ENST00000046087.7
zona pellucida binding protein
chr9_+_129626287 0.02 ENST00000372480.1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr19_-_43575458 0.02 ENST00000262887.10
ENST00000594107.1
ENST00000543982.5
X-ray repair cross complementing 1
chr10_-_67838091 0.02 ENST00000339758.7
DnaJ heat shock protein family (Hsp40) member C12
chr16_-_85688912 0.01 ENST00000253462.8
GINS complex subunit 2
chr2_-_73293538 0.01 ENST00000436467.4
ENST00000545030.1
early growth response 4
chr15_-_55270280 0.01 ENST00000564609.5
RAB27A, member RAS oncogene family
chr12_-_68302872 0.01 ENST00000539972.5
Mdm1 nuclear protein
chr17_-_41982321 0.01 ENST00000587727.6
DnaJ heat shock protein family (Hsp40) member C7
chr2_+_171687457 0.01 ENST00000397119.8
ENST00000410079.7
ENST00000438879.5
dynein cytoplasmic 1 intermediate chain 2
chr17_-_18363504 0.01 ENST00000583780.1
ENST00000316694.8
ENST00000352886.10
serine hydroxymethyltransferase 1
chr11_+_43358908 0.01 ENST00000039989.9
ENST00000299240.10
tetratricopeptide repeat domain 17
chr17_+_76467597 0.00 ENST00000392492.8
aralkylamine N-acetyltransferase
chr17_-_40885232 0.00 ENST00000167588.4
keratin 20

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB16

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 0.9 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 1.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2 0.5 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 0.4 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.5 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 1.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.2 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.2 GO:0015847 putrescine transport(GO:0015847) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.2 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.2 GO:1903004 regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.0 0.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.6 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384) tRNA transcription(GO:0009304)
0.0 0.7 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.6 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0021551 central nervous system morphogenesis(GO:0021551) cardiac muscle tissue regeneration(GO:0061026)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.7 GO:0051180 vitamin transport(GO:0051180)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0043201 response to leucine(GO:0043201)
0.0 0.4 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 1.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.6 GO:0005883 neurofilament(GO:0005883)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 0.7 GO:0008431 vitamin E binding(GO:0008431)
0.2 0.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.4 GO:0030305 heparanase activity(GO:0030305)
0.1 0.4 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.1 0.4 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 0.2 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.1 0.2 GO:0045550 geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.4 GO:0042806 fucose binding(GO:0042806)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 3.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.9 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.7 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin