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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZBTB6

Z-value: 1.54

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Transcription factors associated with ZBTB6

Gene Symbol Gene ID Gene Info
ENSG00000186130.5 zinc finger and BTB domain containing 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB6hg38_v1_chr9_-_122913299_122913333-0.373.6e-01Click!

Activity profile of ZBTB6 motif

Sorted Z-values of ZBTB6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_52452139 6.13 ENST00000252252.4
keratin 6B
chr12_-_52493250 4.75 ENST00000330722.7
keratin 6A
chr1_+_43530847 3.27 ENST00000617451.4
ENST00000359947.9
ENST00000438120.5
protein tyrosine phosphatase receptor type F
chr17_+_56593685 3.05 ENST00000332822.6
noggin
chr12_-_52520371 3.04 ENST00000549420.1
ENST00000252242.9
ENST00000551275.1
ENST00000546577.1
keratin 5
chr5_-_150302884 2.38 ENST00000328668.8
arylsulfatase family member I
chr19_-_35510384 2.03 ENST00000602679.5
ENST00000492341.6
ENST00000472252.6
ENST00000602781.5
ENST00000402589.6
ENST00000458071.5
ENST00000436012.5
ENST00000443640.5
ENST00000450261.1
ENST00000467637.5
ENST00000480502.5
ENST00000474928.5
ENST00000414866.6
ENST00000392206.6
ENST00000488892.5
dermokine
chr12_-_52473798 2.02 ENST00000252250.7
keratin 6C
chr5_+_53480619 1.97 ENST00000396947.7
ENST00000256759.8
follistatin
chr17_+_50532713 1.76 ENST00000503690.5
ENST00000514874.5
ENST00000268933.8
epsin 3
chr17_-_41521719 1.61 ENST00000393976.6
keratin 15
chr6_+_150143018 1.47 ENST00000361131.5
protein phosphatase 1 regulatory inhibitor subunit 14C
chr19_-_14979676 1.43 ENST00000598504.5
ENST00000597262.1
solute carrier family 1 member 6
chr1_+_26529745 1.41 ENST00000374168.7
ENST00000374166.8
ribosomal protein S6 kinase A1
chr15_+_43594027 1.41 ENST00000453733.5
ENST00000441322.6
ENST00000627381.1
creatine kinase, mitochondrial 1B
chr15_+_43693859 1.41 ENST00000413453.7
ENST00000415044.3
ENST00000626814.1
creatine kinase, mitochondrial 1A
chr10_-_47484133 1.39 ENST00000583911.5
ENST00000611843.4
annexin A8
chr10_+_46375645 1.37 ENST00000622769.4
annexin A8 like 1
chrX_+_71910818 1.27 ENST00000633930.1
NHS like 2
chr10_-_47484081 1.27 ENST00000583448.2
ENST00000583874.5
ENST00000585281.6
annexin A8
chr10_+_46375619 1.23 ENST00000584982.7
ENST00000613703.4
annexin A8 like 1
chr12_+_52948840 1.22 ENST00000388837.6
ENST00000550600.5
keratin 18
chr2_+_219627565 1.21 ENST00000273063.10
solute carrier family 4 member 3
chr3_-_190322434 1.21 ENST00000295522.4
claudin 1
chr5_+_140841183 1.20 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr2_+_219627650 1.17 ENST00000317151.7
solute carrier family 4 member 3
chr2_+_219627394 1.17 ENST00000373760.6
solute carrier family 4 member 3
chr2_+_219627622 1.16 ENST00000358055.8
solute carrier family 4 member 3
chr7_+_26152188 1.15 ENST00000056233.4
nuclear factor, erythroid 2 like 3
chr12_+_52949107 1.14 ENST00000388835.4
keratin 18
chr11_+_111540659 1.13 ENST00000375615.7
ENST00000525126.5
ENST00000375614.7
ENST00000533265.5
layilin
chr22_+_44702186 1.11 ENST00000336985.11
ENST00000403696.5
ENST00000457960.5
ENST00000361473.9
proline rich 5
PRR5-ARHGAP8 readthrough
chr3_-_190120881 1.05 ENST00000319332.10
prolyl 3-hydroxylase 2
chr19_+_44809053 1.02 ENST00000611077.5
basal cell adhesion molecule (Lutheran blood group)
chr6_+_30882914 0.95 ENST00000509639.5
ENST00000412274.6
ENST00000507901.5
ENST00000507046.5
ENST00000437124.6
ENST00000454612.6
ENST00000396342.6
discoidin domain receptor tyrosine kinase 1
chr2_+_85133376 0.90 ENST00000282111.4
transcription factor 7 like 1
chr1_+_153778178 0.89 ENST00000532853.5
solute carrier family 27 member 3
chr15_+_45129933 0.84 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
dual oxidase 1
chr5_-_141878396 0.81 ENST00000503492.5
ENST00000287008.8
ENST00000394536.4
protocadherin 1
chr3_-_48429429 0.79 ENST00000358536.8
plexin B1
chr11_+_45922640 0.78 ENST00000401752.6
ENST00000325468.9
LARGE xylosyl- and glucuronyltransferase 2
chr17_+_49495286 0.77 ENST00000172229.8
nerve growth factor receptor
chr9_-_114387973 0.75 ENST00000374088.8
AT-hook transcription factor
chr20_+_6767678 0.73 ENST00000378827.5
bone morphogenetic protein 2
chr7_+_144355288 0.72 ENST00000498580.5
ENST00000056217.10
Rho guanine nucleotide exchange factor 5
chr1_+_1033987 0.72 ENST00000651234.1
ENST00000652369.1
agrin
chr10_-_103855406 0.72 ENST00000355946.6
ENST00000369774.8
SH3 and PX domains 2A
chr9_-_133129395 0.71 ENST00000393157.8
ral guanine nucleotide dissociation stimulator
chr3_-_133895753 0.71 ENST00000460865.3
RAB6B, member RAS oncogene family
chr5_+_140966466 0.69 ENST00000615316.1
ENST00000289269.7
protocadherin alpha subfamily C, 2
chr18_-_50195138 0.67 ENST00000285039.12
myosin VB
chr1_-_54406385 0.63 ENST00000610401.5
single stranded DNA binding protein 3
chr3_-_13880059 0.62 ENST00000285018.5
Wnt family member 7A
chr1_-_18956669 0.62 ENST00000455833.7
intermediate filament family orphan 2
chr16_+_2964216 0.61 ENST00000572045.5
ENST00000571007.5
ENST00000575885.5
ENST00000303746.10
ENST00000319500.10
kringle containing transmembrane protein 2
chr2_-_20225123 0.60 ENST00000254351.9
syndecan 1
chr3_-_116444983 0.60 ENST00000333617.8
limbic system associated membrane protein
chr2_-_20225433 0.60 ENST00000381150.5
syndecan 1
chr10_+_23694707 0.59 ENST00000376462.5
KIAA1217
chr4_-_1406442 0.59 ENST00000422806.2
NK1 homeobox 1
chr6_+_30914329 0.58 ENST00000541562.6
valyl-tRNA synthetase 2, mitochondrial
chr16_+_30740621 0.58 ENST00000615541.3
ENST00000483578.1
transmembrane protein 265
novel transcript
chr4_-_73620391 0.57 ENST00000395777.6
ENST00000307439.10
Ras association domain family member 6
chr12_-_6374803 0.57 ENST00000396966.6
sodium channel epithelial 1 subunit alpha
chr2_-_20225083 0.57 ENST00000403076.5
syndecan 1
chr17_+_28357638 0.57 ENST00000292114.8
ENST00000591482.1
transmembrane protein 199
novel transcript readthrough between TMEM199 and SARM1
chr18_-_26548527 0.57 ENST00000580059.7
potassium channel tetramerization domain containing 1
chr6_+_30914205 0.56 ENST00000672801.1
ENST00000321897.9
ENST00000625423.2
ENST00000676266.1
ENST00000428017.5
valyl-tRNA synthetase 2, mitochondrial
chr18_+_31498168 0.56 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr8_+_31639222 0.56 ENST00000519301.6
ENST00000652698.1
neuregulin 1
chr6_-_30744537 0.56 ENST00000259874.6
ENST00000376377.2
immediate early response 3
chr19_+_1507976 0.56 ENST00000673796.1
polo like kinase 5 (inactive)
chr10_+_127907036 0.55 ENST00000254667.8
ENST00000442830.5
protein tyrosine phosphatase receptor type E
chr22_+_32801697 0.55 ENST00000266085.7
TIMP metallopeptidase inhibitor 3
chr6_+_137871208 0.54 ENST00000614035.4
ENST00000621150.3
ENST00000619035.4
ENST00000615468.4
ENST00000620204.3
TNF alpha induced protein 3
chr18_+_58149314 0.54 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4 like E3 ubiquitin protein ligase
chr8_-_544825 0.53 ENST00000324079.11
testis development related protein
chr4_+_152936315 0.52 ENST00000511601.6
FH2 domain containing 1
chr4_+_151409169 0.51 ENST00000435205.6
family with sequence similarity 160 member A1
chr15_-_74725370 0.50 ENST00000567032.5
ENST00000564596.5
ENST00000566503.1
ENST00000395049.8
ENST00000379727.8
ENST00000617691.4
ENST00000395048.6
cytochrome P450 family 1 subfamily A member 1
chr10_+_132397168 0.50 ENST00000631148.2
ENST00000305233.6
PWWP domain containing 2B
chr10_-_102120246 0.50 ENST00000425280.2
LIM domain binding 1
chr8_+_31639291 0.50 ENST00000651149.1
ENST00000650866.1
neuregulin 1
chr19_+_41193198 0.50 ENST00000597754.1
ENST00000310054.9
cytochrome P450 family 2 subfamily S member 1
chr20_+_62656359 0.47 ENST00000370507.5
solute carrier organic anion transporter family member 4A1
chr2_+_147844601 0.47 ENST00000404590.1
activin A receptor type 2A
chr19_-_51026593 0.47 ENST00000600362.5
ENST00000453757.8
ENST00000601671.1
kallikrein related peptidase 11
chrX_-_120311533 0.47 ENST00000440464.5
ENST00000519908.1
transmembrane protein 255A
chr20_-_45910898 0.46 ENST00000372420.5
phospholipid transfer protein
chr19_+_55075862 0.46 ENST00000201647.11
EPS8 like 1
chr21_+_45405117 0.45 ENST00000651438.1
collagen type XVIII alpha 1 chain
chr11_+_63839173 0.45 ENST00000502399.7
ENST00000425897.3
ENST00000513765.7
ENST00000679216.1
microtubule affinity regulating kinase 2
chr12_+_50504970 0.45 ENST00000301180.10
disco interacting protein 2 homolog B
chr12_-_6375209 0.45 ENST00000360168.7
sodium channel epithelial 1 subunit alpha
chrX_-_120311452 0.44 ENST00000371369.9
transmembrane protein 255A
chr1_+_220528112 0.44 ENST00000366917.6
ENST00000402574.5
ENST00000611084.4
ENST00000366918.8
microtubule affinity regulating kinase 1
chrX_+_132023294 0.44 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chr14_-_21526312 0.44 ENST00000537235.2
spalt like transcription factor 2
chr4_+_158210479 0.44 ENST00000504569.5
ENST00000509278.5
ENST00000514558.5
ENST00000503200.5
ENST00000296529.11
transmembrane protein 144
chr5_-_79514127 0.43 ENST00000334082.11
homer scaffold protein 1
chr1_+_220528785 0.43 ENST00000678435.1
microtubule affinity regulating kinase 1
chr1_+_45500287 0.43 ENST00000401061.9
ENST00000616135.1
metabolism of cobalamin associated C
chrX_-_120311408 0.42 ENST00000309720.9
transmembrane protein 255A
chr1_+_14945775 0.42 ENST00000400797.3
kazrin, periplakin interacting protein
chr3_+_10816201 0.41 ENST00000454147.1
ENST00000254488.7
solute carrier family 6 member 11
chr8_+_103500696 0.41 ENST00000666250.1
ENST00000668113.1
ENST00000504942.6
ENST00000632716.1
regulating synaptic membrane exocytosis 2
chr1_+_220528333 0.41 ENST00000677505.1
microtubule affinity regulating kinase 1
chr11_-_72794032 0.41 ENST00000334805.11
StAR related lipid transfer domain containing 10
chr1_+_206507520 0.40 ENST00000579436.7
Ras association domain family member 5
chr5_+_140794832 0.40 ENST00000378132.2
ENST00000526136.2
ENST00000520672.2
protocadherin alpha 2
chr6_+_150683593 0.39 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr2_+_202634960 0.39 ENST00000392238.3
family with sequence similarity 117 member B
chr9_-_130939205 0.38 ENST00000372338.9
fibrinogen C domain containing 1
chr14_-_91060113 0.38 ENST00000536315.6
ribosomal protein S6 kinase A5
chr8_-_143578315 0.37 ENST00000449291.7
ENST00000435154.7
ENST00000426292.7
nicotinate phosphoribosyltransferase
chr16_+_3046552 0.37 ENST00000336577.9
matrix metallopeptidase 25
chr14_-_21526391 0.37 ENST00000611430.4
spalt like transcription factor 2
chr10_-_102120318 0.37 ENST00000673968.1
LIM domain binding 1
chr2_-_96116565 0.37 ENST00000620793.2
adrenoceptor alpha 2B
chr3_-_27484374 0.37 ENST00000445684.5
ENST00000425128.6
solute carrier family 4 member 7
chr19_+_55075897 0.37 ENST00000540810.5
EPS8 like 1
chr1_+_206507546 0.36 ENST00000580449.5
ENST00000581503.6
Ras association domain family member 5
chr10_-_101775974 0.36 ENST00000346714.7
ENST00000347978.2
fibroblast growth factor 8
chr1_-_109397888 0.35 ENST00000256637.8
sortilin 1
chr6_-_142946312 0.35 ENST00000367604.6
HIVEP zinc finger 2
chr2_+_147844488 0.35 ENST00000535787.5
activin A receptor type 2A
chr4_-_73620629 0.35 ENST00000342081.7
Ras association domain family member 6
chr1_-_204411804 0.35 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr17_+_82458174 0.35 ENST00000579198.5
ENST00000390006.8
ENST00000580296.5
nuclear prelamin A recognition factor
chr6_-_6006878 0.34 ENST00000244766.7
neuritin 1
chr6_+_70413417 0.34 ENST00000505769.5
ENST00000515323.5
family with sequence similarity 135 member A
chr3_+_129001581 0.34 ENST00000436022.2
EF-hand and coiled-coil domain containing 1
chr16_+_56191476 0.34 ENST00000262493.12
G protein subunit alpha o1
chr6_+_70413462 0.33 ENST00000418814.7
ENST00000515280.5
ENST00000507085.5
ENST00000457062.6
ENST00000361499.7
family with sequence similarity 135 member A
chr10_+_125896549 0.33 ENST00000368693.6
fibronectin type III and ankyrin repeat domains 1
chr22_-_46537593 0.33 ENST00000262738.9
ENST00000674500.2
cadherin EGF LAG seven-pass G-type receptor 1
chr3_+_129001298 0.33 ENST00000683648.1
EF-hand and coiled-coil domain containing 1
chr1_-_92961440 0.32 ENST00000370310.5
ENST00000615519.4
ENST00000613902.4
ENST00000616709.4
divergent protein kinase domain 1A
chr16_-_11586903 0.32 ENST00000571459.5
ENST00000570798.5
ENST00000622633.5
ENST00000572255.5
ENST00000574763.5
ENST00000574703.5
ENST00000571277.1
lipopolysaccharide induced TNF factor
chr4_-_25862979 0.32 ENST00000399878.8
SEL1L family member 3
chr19_+_17751467 0.32 ENST00000596536.5
ENST00000593870.5
ENST00000598086.5
ENST00000598932.5
ENST00000595023.5
ENST00000594068.5
ENST00000596507.5
ENST00000595033.5
ENST00000597718.5
FCH and mu domain containing endocytic adaptor 1
chr17_-_45410414 0.32 ENST00000532038.5
ENST00000528677.1
Rho GTPase activating protein 27
chr3_-_133895453 0.32 ENST00000486858.5
ENST00000477759.5
RAB6B, member RAS oncogene family
chr17_+_82458649 0.32 ENST00000345415.11
ENST00000412079.6
ENST00000457415.7
ENST00000584411.5
ENST00000577432.5
nuclear prelamin A recognition factor
chr2_+_147845020 0.31 ENST00000241416.12
activin A receptor type 2A
chr10_+_102065322 0.31 ENST00000299238.7
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3
chr11_+_68460712 0.31 ENST00000528635.5
ENST00000533127.5
ENST00000529907.5
ENST00000529344.5
ENST00000534534.5
ENST00000524845.5
ENST00000393800.7
ENST00000265637.8
ENST00000524904.5
ENST00000393801.7
ENST00000265636.9
ENST00000529710.5
protein phosphatase 6 regulatory subunit 3
chr9_+_68705414 0.31 ENST00000541509.5
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr19_-_16627943 0.30 ENST00000611692.4
mediator complex subunit 26
chr17_-_44324770 0.30 ENST00000592857.5
ENST00000586016.5
ENST00000590194.5
ENST00000588049.5
ENST00000586633.5
ENST00000377095.10
ENST00000537904.6
ENST00000585636.5
ENST00000585523.1
ENST00000225308.12
solute carrier family 25 member 39
chr17_+_7705193 0.30 ENST00000226091.3
ephrin B3
chr14_-_91060578 0.30 ENST00000418736.6
ENST00000614987.5
ribosomal protein S6 kinase A5
chr3_-_27484335 0.30 ENST00000454389.5
ENST00000440156.5
ENST00000437179.5
ENST00000446700.5
ENST00000455077.5
solute carrier family 4 member 7
chr5_+_79689825 0.30 ENST00000446378.3
cardiomyopathy associated 5
chr10_+_102152380 0.30 ENST00000605788.6
ENST00000488254.6
ENST00000461421.5
ENST00000476468.5
ENST00000370007.5
nucleolar and coiled-body phosphoprotein 1
chr16_-_11586941 0.30 ENST00000571976.1
ENST00000413364.6
lipopolysaccharide induced TNF factor
chr16_+_2009870 0.29 ENST00000567649.1
neuropeptide W
chr16_-_11587162 0.29 ENST00000570904.5
ENST00000574701.5
lipopolysaccharide induced TNF factor
chr4_+_41256921 0.29 ENST00000284440.9
ENST00000508768.5
ENST00000512788.1
ubiquitin C-terminal hydrolase L1
chr11_-_66546021 0.29 ENST00000310442.5
zinc finger DHHC-type containing 24
chr12_-_64222239 0.29 ENST00000311915.12
ENST00000398055.8
ENST00000544871.1
chromosome 12 open reading frame 66
chr3_+_38453832 0.28 ENST00000352511.5
activin A receptor type 2B
chr4_+_88457110 0.28 ENST00000264350.8
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr1_-_45500040 0.28 ENST00000629482.3
coiled-coil domain containing 163
chr1_+_110034607 0.28 ENST00000369795.8
striatin interacting protein 1
chr8_+_123416735 0.28 ENST00000524254.5
N-terminal glutamine amidase 1
chr16_+_1706163 0.28 ENST00000250894.8
ENST00000673691.1
ENST00000356010.9
ENST00000610761.2
mitogen-activated protein kinase 8 interacting protein 3
chr15_-_51738095 0.28 ENST00000560491.2
LysM domain containing 2
chr12_+_11649666 0.28 ENST00000396373.9
ETS variant transcription factor 6
chr18_+_62715526 0.28 ENST00000262719.10
PH domain and leucine rich repeat protein phosphatase 1
chr9_+_68705230 0.28 ENST00000265382.8
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr4_-_25863537 0.27 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr6_-_6007511 0.27 ENST00000616243.1
neuritin 1
chr19_-_49361475 0.27 ENST00000598810.5
TEA domain transcription factor 2
chr3_-_59049947 0.27 ENST00000491845.5
ENST00000472469.5
ENST00000482387.6
ENST00000295966.11
CFAP20 domain containing
chr9_+_84669760 0.27 ENST00000304053.10
neurotrophic receptor tyrosine kinase 2
chr11_+_68312542 0.27 ENST00000294304.12
LDL receptor related protein 5
chr10_-_101776104 0.27 ENST00000320185.7
ENST00000344255.8
fibroblast growth factor 8
chr17_-_7252054 0.26 ENST00000575783.5
ENST00000573600.5
CTD nuclear envelope phosphatase 1
chr2_+_202073282 0.26 ENST00000459709.5
KIAA2012
chr2_+_202073249 0.26 ENST00000498697.3
KIAA2012
chr10_-_119165542 0.26 ENST00000419372.5
ENST00000369131.8
ENST00000355697.7
sideroflexin 4
chr18_+_44680093 0.26 ENST00000426838.8
ENST00000677068.1
SET binding protein 1
chr10_+_102152169 0.26 ENST00000405356.5
nucleolar and coiled-body phosphoprotein 1
chr16_+_81495340 0.25 ENST00000539778.6
c-Maf inducing protein
chr16_-_67416420 0.25 ENST00000348579.6
ENST00000565726.3
zinc finger DHHC-type containing 1
chr1_-_11805924 0.25 ENST00000418034.1
methylenetetrahydrofolate reductase
chrX_+_69616067 0.25 ENST00000338901.4
ENST00000525810.5
ENST00000527388.5
ENST00000374553.6
ENST00000374552.9
ENST00000524573.5
ectodysplasin A
chr6_+_156777882 0.25 ENST00000350026.10
ENST00000647938.1
ENST00000674298.1
AT-rich interaction domain 1B
chr5_+_139795795 0.25 ENST00000274710.4
pleckstrin and Sec7 domain containing 2
chr12_+_48119323 0.24 ENST00000551339.6
ENST00000629846.2
ENST00000359794.11
ENST00000548345.5
phosphofructokinase, muscle
chr17_+_43398984 0.24 ENST00000320033.5
ADP ribosylation factor like GTPase 4D
chrY_+_6246223 0.24 ENST00000429039.5
ENST00000320701.8
ENST00000383042.1
testis specific protein Y-linked 2
chr6_+_43076262 0.24 ENST00000476760.1
ENST00000230419.9
ENST00000471863.5
ENST00000345201.6
ENST00000349241.6
ENST00000352931.6
protein tyrosine kinase 7 (inactive)
chr19_-_42242526 0.24 ENST00000222330.8
ENST00000676537.1
glycogen synthase kinase 3 alpha
chr4_+_7192519 0.24 ENST00000507866.6
sortilin related VPS10 domain containing receptor 2
chr8_+_123416718 0.24 ENST00000523984.5
N-terminal glutamine amidase 1
chr1_+_5992639 0.24 ENST00000666163.1
ENST00000671676.1
ENST00000658883.1
ENST00000445501.6
ENST00000668706.1
ENST00000653262.1
ENST00000389632.9
ENST00000341524.6
ENST00000462676.3
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr8_+_143368869 0.24 ENST00000289013.11
rhophilin Rho GTPase binding protein 1
chr15_+_67521693 0.24 ENST00000557807.1
chromosome 15 open reading frame 61

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
1.0 3.1 GO:1905006 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.8 2.4 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.7 2.7 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.6 0.6 GO:0060066 oviduct development(GO:0060066)
0.5 2.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.5 1.4 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.4 1.8 GO:0048627 myoblast development(GO:0048627)
0.4 3.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.4 1.2 GO:0071284 establishment of blood-nerve barrier(GO:0008065) cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
0.3 0.9 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.3 0.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.3 1.6 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.2 0.7 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.2 0.8 GO:0042335 cuticle development(GO:0042335)
0.2 1.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 0.7 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 0.5 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.2 6.3 GO:0007398 ectoderm development(GO:0007398)
0.2 0.5 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.2 1.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 0.5 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.1 0.7 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:0019542 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.1 0.8 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 2.0 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.1 0.5 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 3.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.5 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.6 GO:0002357 defense response to tumor cell(GO:0002357)
0.1 0.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 1.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.6 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 1.4 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.4 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.7 GO:0032439 endosome localization(GO:0032439)
0.1 0.6 GO:0003164 His-Purkinje system development(GO:0003164)
0.1 0.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.3 GO:0097069 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.1 0.3 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 1.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.6 GO:0007506 gonadal mesoderm development(GO:0007506)
0.1 0.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.2 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 4.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.6 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1 1.1 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.2 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0015692 lead ion transport(GO:0015692)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.7 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 0.3 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.2 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.4 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 0.1 GO:0035732 nitric oxide storage(GO:0035732)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.0 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.2 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.4 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:0036048 protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698) peptidyl-lysine deglutarylation(GO:0061699)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.5 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:0019230 proprioception(GO:0019230)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.2 GO:0032903 viral protein processing(GO:0019082) negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.2 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.0 0.6 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0048560 establishment of anatomical structure orientation(GO:0048560)
0.0 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.0 1.8 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.1 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.0 0.3 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.1 GO:0032759 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:1903971 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 0.2 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.3 GO:0002249 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.3 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
0.0 0.2 GO:0019086 late viral transcription(GO:0019086)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:1900107 embryonic hindgut morphogenesis(GO:0048619) regulation of nodal signaling pathway(GO:1900107)
0.0 0.1 GO:0042414 phthalate metabolic process(GO:0018963) epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418) phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.6 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.0 0.5 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.1 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0005999 xylulose biosynthetic process(GO:0005999)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.2 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.4 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.0 GO:0021558 trochlear nerve development(GO:0021558)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 1.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.3 GO:0030903 notochord development(GO:0030903)
0.0 1.8 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.9 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.0 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) histone H3-R2 methylation(GO:0034970)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684) positive regulation of tooth mineralization(GO:0070172)
0.0 0.5 GO:1903205 regulation of hydrogen peroxide-induced cell death(GO:1903205)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.0 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.0 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.2 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 17.7 GO:0045095 keratin filament(GO:0045095)
0.1 0.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.9 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.3 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.7 GO:0045179 apical cortex(GO:0045179)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 1.2 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.3 GO:0005816 spindle pole body(GO:0005816)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 3.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 2.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.0 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 1.0 GO:0005055 laminin receptor activity(GO:0005055)
0.3 1.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.3 1.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 4.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.4 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 1.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.5 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.1 2.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.1 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 1.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 2.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.5 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.4 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.6 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 1.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.1 0.8 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 2.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.2 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 15.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 2.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.8 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 2.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.3 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.3 GO:0042835 BRE binding(GO:0042835)
0.1 0.2 GO:0070905 serine binding(GO:0070905)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.4 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.2 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0061697 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 1.6 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.0 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) pyrimidine ribonucleotide binding(GO:0032557)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.3 PID BMP PATHWAY BMP receptor signaling
0.0 4.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 5.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 ST GAQ PATHWAY G alpha q Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 5.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 2.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 0.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 2.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 4.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 3.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives