Epithelial-Mesenchymal Transition, human (Scheel, 2011)
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
ZEB1 | hg38_v1_chr10_+_31319125_31319227 | -0.99 | 1.5e-06 | Click! |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
chr14_-_61281310 Show fit | 33.39 |
ENST00000555868.2
|
transmembrane protein 30B |
|
chr8_+_94641199 Show fit | 31.55 |
ENST00000646773.1
ENST00000454170.7 |
epithelial splicing regulatory protein 1 |
|
chr8_+_94641145 Show fit | 30.32 |
ENST00000433389.8
ENST00000358397.9 |
epithelial splicing regulatory protein 1 |
|
chr8_+_94641074 Show fit | 29.90 |
ENST00000423620.6
|
epithelial splicing regulatory protein 1 |
|
chr6_-_136550407 Show fit | 27.99 |
ENST00000354570.8
|
microtubule associated protein 7 |
|
chr19_+_38264563 Show fit | 25.46 |
ENST00000301244.12
ENST00000587090.5 ENST00000454580.7 |
serine peptidase inhibitor, Kunitz type 2 |
|
chr19_+_35248656 Show fit | 25.45 |
ENST00000621372.4
|
lipolysis stimulated lipoprotein receptor |
|
chr19_+_35248694 Show fit | 25.35 |
ENST00000361790.7
|
lipolysis stimulated lipoprotein receptor |
|
chr19_+_35248879 Show fit | 25.34 |
ENST00000347609.8
|
lipolysis stimulated lipoprotein receptor |
|
chr19_+_35248728 Show fit | 25.22 |
ENST00000602003.1
ENST00000360798.7 ENST00000354900.7 |
lipolysis stimulated lipoprotein receptor |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
23.4 | 140.2 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
0.6 | 102.6 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
1.1 | 98.2 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
2.1 | 57.4 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
7.8 | 54.5 | GO:0010482 | epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482) |
12.3 | 49.1 | GO:0060671 | epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672) |
1.6 | 40.6 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
0.2 | 39.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
4.9 | 39.1 | GO:0086042 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) |
0.5 | 36.4 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 276.3 | GO:0016021 | integral component of membrane(GO:0016021) |
15.0 | 150.1 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.6 | 115.1 | GO:0070160 | occluding junction(GO:0070160) |
0.1 | 99.9 | GO:0016604 | nuclear body(GO:0016604) |
2.4 | 81.8 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.5 | 61.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.4 | 48.4 | GO:0070821 | tertiary granule membrane(GO:0070821) |
1.5 | 47.3 | GO:0030057 | desmosome(GO:0030057) |
1.7 | 44.9 | GO:0005922 | connexon complex(GO:0005922) |
0.2 | 39.4 | GO:0005875 | microtubule associated complex(GO:0005875) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 99.6 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
0.2 | 67.4 | GO:0045296 | cadherin binding(GO:0045296) |
0.2 | 66.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.7 | 53.4 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.6 | 47.7 | GO:0019894 | kinesin binding(GO:0019894) |
0.7 | 45.6 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
0.7 | 43.3 | GO:0042379 | chemokine receptor binding(GO:0042379) |
1.4 | 42.7 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.3 | 42.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
5.1 | 41.0 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 84.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
1.5 | 59.8 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.5 | 38.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
2.0 | 38.8 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
0.9 | 37.0 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.8 | 31.3 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
0.4 | 28.8 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
0.3 | 23.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
0.6 | 22.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
0.4 | 22.2 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 78.8 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
2.1 | 54.8 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
1.9 | 44.9 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
1.1 | 40.6 | REACTOME CELL CELL JUNCTION ORGANIZATION | Genes involved in Cell-cell junction organization |
0.3 | 36.8 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
0.9 | 33.6 | REACTOME KINESINS | Genes involved in Kinesins |
0.6 | 31.2 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
0.8 | 29.1 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.5 | 25.8 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
0.7 | 24.5 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |