Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
ZFHX3 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000140836.17	zinc finger homeobox 3

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZFHX3	hg38_v1_chr16_-_73048104_73048136	-0.21	6.3e-01	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_+_73481737 Show fit	0.14	ENST00000226355.5	AFM Links Ensembl NCBI GeneCards UniProt NextProt Show fit	afamin
chr3_-_114758940 Show fit	0.13	ENST00000464560.5	ZBTB20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and BTB domain containing 20
chr4_-_154590735 Show fit	0.12	ENST00000403106.8 ENST00000622532.1 ENST00000651975.1	FGA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fibrinogen alpha chain
chr7_+_130486171 Show fit	0.08	ENST00000341441.9 ENST00000416162.7	MEST Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mesoderm specific transcript
chr7_+_130486324 Show fit	0.08	ENST00000427521.6 ENST00000378576.9	MEST Links Ensembl NCBI GeneCards UniProt NextProt Show fit	mesoderm specific transcript
chrX_-_32155462 Show fit	0.08	ENST00000359836.5 ENST00000378707.7 ENST00000541735.5 ENST00000684130.1 ENST00000682238.1 ENST00000620040.5 ENST00000474231.5	DMD Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dystrophin
chr14_-_100569780 Show fit	0.08	ENST00000355173.7	BEGAIN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	brain enriched guanylate kinase associated
chr1_-_247758680 Show fit	0.07	ENST00000408896.4	OR1C1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactory receptor family 1 subfamily C member 1
chr8_+_103819244 Show fit	0.07	ENST00000262231.14 ENST00000507740.5 ENST00000408894.6	RIMS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	regulating synaptic membrane exocytosis 2
chr8_-_69833338 Show fit	0.07	ENST00000524945.5	SLCO5A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier organic anion transporter family member 5A1
chr9_-_121050264 Show fit	0.06	ENST00000223642.3	C5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	complement C5
chr3_-_165078480 Show fit	0.06	ENST00000264382.8	SI Links Ensembl NCBI GeneCards UniProt NextProt Show fit	sucrase-isomaltase
chr6_-_29045175 Show fit	0.05	ENST00000377175.2	OR2W1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactory receptor family 2 subfamily W member 1
chr5_-_35195236 Show fit	0.05	ENST00000509839.5	PRLR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	prolactin receptor
chr6_+_29111560 Show fit	0.05	ENST00000377169.2	OR2J3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactory receptor family 2 subfamily J member 3
chr19_-_58353482 Show fit	0.05	ENST00000263100.8	A1BG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	alpha-1-B glycoprotein
chr12_+_53954870 Show fit	0.05	ENST00000243103.4	HOXC12 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox C12
chr14_+_94561435 Show fit	0.05	ENST00000557004.6 ENST00000555095.5 ENST00000298841.5 ENST00000554220.5 ENST00000553780.5	SERPINA4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit SERPINA5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin family A member 4 serpin family A member 5
chr1_+_159587817 Show fit	0.05	ENST00000255040.3	APCS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	amyloid P component, serum
chr18_-_55422306 Show fit	0.04	ENST00000566777.5 ENST00000626584.2	TCF4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transcription factor 4
chr7_-_100428657 Show fit	0.04	ENST00000360951.8 ENST00000398027.6 ENST00000684423.1 ENST00000472716.1	ZCWPW1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger CW-type and PWWP domain containing 1
chr2_-_60553409 Show fit	0.04	ENST00000358510.6 ENST00000643004.1	BCL11A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BAF chromatin remodeling complex subunit BCL11A
chr6_-_154430495 Show fit	0.04	ENST00000424998.3	CNKSR3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CNKSR family member 3
chr8_-_144529048 Show fit	0.04	ENST00000527462.1 ENST00000313465.5 ENST00000524821.6	C8orf82 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 8 open reading frame 82
chr15_+_76336755 Show fit	0.04	ENST00000290759.9	ISL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ISL LIM homeobox 2
chr2_-_60553558 Show fit	0.04	ENST00000642439.1 ENST00000356842.9	BCL11A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BAF chromatin remodeling complex subunit BCL11A
chr4_-_99435134 Show fit	0.04	ENST00000476959.5 ENST00000482593.5	ADH7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_-_157503339 Show fit	0.04	ENST00000392833.6	VEPH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ventricular zone expressed PH domain containing 1
chr3_-_157503375 Show fit	0.04	ENST00000362010.7	VEPH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ventricular zone expressed PH domain containing 1
chr22_+_38705922 Show fit	0.03	ENST00000216044.10	GTPBP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GTP binding protein 1
chrX_+_103376389 Show fit	0.03	ENST00000372645.3 ENST00000372635.1	BEX3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	brain expressed X-linked 3
chr5_+_119354771 Show fit	0.03	ENST00000503646.1	TNFAIP8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TNF alpha induced protein 8
chr14_+_39233908 Show fit	0.03	ENST00000280082.4	MIA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MIA SH3 domain ER export factor 2
chr12_+_130953898 Show fit	0.03	ENST00000261654.10	ADGRD1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adhesion G protein-coupled receptor D1
chr2_-_87021844 Show fit	0.03	ENST00000355705.4 ENST00000409310.6	PLGLB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	plasminogen like B1
chr4_-_151227881 Show fit	0.03	ENST00000652233.1 ENST00000514152.5	SH3D19 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SH3 domain containing 19
chr4_-_148444674 Show fit	0.03	ENST00000344721.8	NR3C2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nuclear receptor subfamily 3 group C member 2
chr4_+_3441960 Show fit	0.03	ENST00000382774.8 ENST00000511533.1	HGFAC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	HGF activator
chr15_+_58431985 Show fit	0.03	ENST00000433326.2 ENST00000299022.10	LIPC Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lipase C, hepatic type
chr11_+_8019193 Show fit	0.03	ENST00000534099.5	TUB Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TUB bipartite transcription factor
chr2_+_184598520 Show fit	0.03	ENST00000302277.7	ZNF804A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger protein 804A
chr6_-_116060859 Show fit	0.03	ENST00000606080.2	FRK Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fyn related Src family tyrosine kinase
chr2_-_2324642 Show fit	0.02	ENST00000650485.1 ENST00000649207.1	MYT1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin transcription factor 1 like
chr3_+_35680994 Show fit	0.02	ENST00000441454.5	ARPP21 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cAMP regulated phosphoprotein 21
chr14_+_64704380 Show fit	0.02	ENST00000247226.13 ENST00000394691.7	PLEKHG3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	pleckstrin homology and RhoGEF domain containing G3
chr5_+_141245384 Show fit	0.02	ENST00000623671.1 ENST00000231173.6	PCDHB15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protocadherin beta 15
chr17_+_17782108 Show fit	0.02	ENST00000395774.1	RAI1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	retinoic acid induced 1
chr9_-_123184233 Show fit	0.02	ENST00000447404.6	STRBP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spermatid perinuclear RNA binding protein
chr1_-_160579439 Show fit	0.02	ENST00000368054.8 ENST00000368048.7 ENST00000311224.8 ENST00000368051.3 ENST00000534968.5	CD84 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	CD84 molecule
chr18_+_34976928 Show fit	0.02	ENST00000591734.5 ENST00000413393.5 ENST00000589180.5 ENST00000587359.5	MAPRE2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microtubule associated protein RP/EB family member 2
chr3_-_157503574 Show fit	0.02	ENST00000494677.5 ENST00000468233.5	VEPH1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ventricular zone expressed PH domain containing 1
chr3_-_39280021 Show fit	0.02	ENST00000399220.3	CX3CR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	C-X3-C motif chemokine receptor 1
chr17_+_7407838 Show fit	0.02	ENST00000302926.7	NLGN2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	neuroligin 2
chr4_+_70592253 Show fit	0.02	ENST00000322937.10 ENST00000613447.4	AMBN Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ameloblastin
chr12_-_101407727 Show fit	0.02	ENST00000539055.5 ENST00000551688.1 ENST00000551671.5 ENST00000261636.13	ARL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP ribosylation factor like GTPase 1
chr2_-_60553618 Show fit	0.02	ENST00000643716.1 ENST00000359629.10 ENST00000642384.2 ENST00000335712.11	BCL11A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	BAF chromatin remodeling complex subunit BCL11A
chr11_+_5389377 Show fit	0.02	ENST00000328611.5	OR51M1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactory receptor family 51 subfamily M member 1
chr6_+_47781982 Show fit	0.02	ENST00000489301.6 ENST00000638973.1 ENST00000371211.6 ENST00000393699.2	OPN5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	opsin 5
chr20_+_43558968 Show fit	0.02	ENST00000647834.1 ENST00000373100.7 ENST00000648083.1 ENST00000648530.1	SGK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serum/glucocorticoid regulated kinase 2
chr2_+_233712905 Show fit	0.02	ENST00000373414.4	UGT1A5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP glucuronosyltransferase family 1 member A5
chr12_-_7665897 Show fit	0.02	ENST00000229304.5	APOBEC1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein B mRNA editing enzyme catalytic subunit 1
chr12_-_68159732 Show fit	0.02	ENST00000229135.4	IFNG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	interferon gamma
chr2_+_87748087 Show fit	0.02	ENST00000359481.9	PLGLB2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	plasminogen like B2
chr6_-_127918604 Show fit	0.01	ENST00000537166.5	THEMIS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thymocyte selection associated
chr6_+_28349907 Show fit	0.01	ENST00000252211.7 ENST00000341464.9 ENST00000377255.3	ZKSCAN3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger with KRAB and SCAN domains 3
chr2_-_2324323 Show fit	0.01	ENST00000648339.1 ENST00000647694.1	MYT1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin transcription factor 1 like
chr17_-_40999903 Show fit	0.01	ENST00000391587.3	KRTAP3-2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	keratin associated protein 3-2
chr6_-_127918540 Show fit	0.01	ENST00000368250.5	THEMIS Links Ensembl NCBI GeneCards UniProt NextProt Show fit	thymocyte selection associated
chr11_-_61920267 Show fit	0.01	ENST00000531922.2 ENST00000301773.9	RAB3IL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB3A interacting protein like 1
chr2_+_233729042 Show fit	0.01	ENST00000482026.6	UGT1A3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP glucuronosyltransferase family 1 member A3
chr22_-_30246739 Show fit	0.01	ENST00000403987.3 ENST00000249075.4	LIF Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LIF interleukin 6 family cytokine
chr6_+_160702238 Show fit	0.01	ENST00000366924.6 ENST00000308192.14 ENST00000418964.1	PLG Links Ensembl NCBI GeneCards UniProt NextProt Show fit	plasminogen
chr2_+_233718734 Show fit	0.01	ENST00000373409.8	UGT1A4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	UDP glucuronosyltransferase family 1 member A4
chr1_-_66801276 Show fit	0.01	ENST00000304526.3	INSL5 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin like 5
chr6_+_157036315 Show fit	0.01	ENST00000637904.1	ARID1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	AT-rich interaction domain 1B
chr4_+_99574812 Show fit	0.01	ENST00000422897.6 ENST00000265517.10	MTTP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	microsomal triglyceride transfer protein
chrX_-_15601077 Show fit	0.01	ENST00000680121.1	ACE2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	angiotensin I converting enzyme 2
chr20_-_7940444 Show fit	0.01	ENST00000378789.4	HAO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	hydroxyacid oxidase 1
chr12_+_53441724 Show fit	0.01	ENST00000551003.5 ENST00000429243.7 ENST00000549068.5 ENST00000549740.5 ENST00000546581.5 ENST00000549581.5 ENST00000547368.5 ENST00000379786.8 ENST00000551945.5 ENST00000547717.1	PRR13 Links Ensembl NCBI GeneCards UniProt NextProt Show fit ENSG00000257379.1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	proline rich 13 novel transcript
chr6_-_32407123 Show fit	0.01	ENST00000374993.4 ENST00000544175.2 ENST00000454136.7 ENST00000446536.2	BTNL2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	butyrophilin like 2
chr3_-_49029378 Show fit	0.01	ENST00000442157.2 ENST00000326739.9 ENST00000677010.1 ENST00000678724.1 ENST00000429182.6	IMPDH2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	inosine monophosphate dehydrogenase 2
chr8_-_140764386 Show fit	0.01	ENST00000520151.5 ENST00000519024.5 ENST00000519465.5	PTK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein tyrosine kinase 2
chr6_-_30932147 Show fit	0.01	ENST00000359086.4	SFTA2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	surfactant associated 2
chrX_+_16650155 Show fit	0.01	ENST00000380200.3	S100G Links Ensembl NCBI GeneCards UniProt NextProt Show fit	S100 calcium binding protein G
chr11_+_74748831 Show fit	0.01	ENST00000299563.5	RNF169 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ring finger protein 169
chrX_+_85003863 Show fit	0.01	ENST00000373173.7	APOOL Links Ensembl NCBI GeneCards UniProt NextProt Show fit	apolipoprotein O like
chr6_-_160664270 Show fit	0.00	ENST00000316300.10	LPA Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lipoprotein(a)
chr22_-_30574572 Show fit	0.00	ENST00000402369.5	GAL3ST1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	galactose-3-O-sulfotransferase 1
chr6_-_2971048 Show fit	0.00	ENST00000612421.3	SERPINB6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	serpin family B member 6
chr12_+_64497968 Show fit	0.00	ENST00000676593.1 ENST00000677093.1	TBK1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit ENSG00000288665.1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TANK binding kinase 1 novel transcript
chr16_+_56191476 Show fit	0.00	ENST00000262493.12	GNAO1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	G protein subunit alpha o1
chr18_+_58341038 Show fit	0.00	ENST00000679791.1	NEDD4L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr16_-_69351778 Show fit	0.00	ENST00000288025.4	TMED6 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane p24 trafficking protein 6
chr6_-_116126120 Show fit	0.00	ENST00000452729.1 ENST00000651968.1 ENST00000243222.8	COL10A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen type X alpha 1 chain
chr1_-_153613095 Show fit	0.00	ENST00000368706.9	S100A16 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	S100 calcium binding protein A16
chr19_-_45730861 Show fit	0.00	ENST00000317683.4	FBXO46 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	F-box protein 46

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:2000173	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.0	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
0.0	0.0	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	GO:0036029	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0008431	vitamin E binding(GO:0008431)
0.0	0.1	GO:0004925	prolactin receptor activity(GO:0004925)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)