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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZIC1

Z-value: 0.34

Motif logo

Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ENSG00000152977.10 Zic family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC1hg38_v1_chr3_+_147409357_147409381-0.078.8e-01Click!

Activity profile of ZIC1 motif

Sorted Z-values of ZIC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_3028356 0.18 ENST00000586422.5
TLE family member 2, transcriptional corepressor
chr8_-_119673368 0.16 ENST00000427067.6
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr13_+_101452629 0.16 ENST00000622834.4
ENST00000545560.6
ENST00000376180.8
integrin subunit beta like 1
chr13_+_101452569 0.15 ENST00000618057.4
integrin subunit beta like 1
chr17_-_44968263 0.13 ENST00000253407.4
complement C1q like 1
chr6_+_132570322 0.13 ENST00000275198.1
trace amine associated receptor 6
chr9_-_16870702 0.13 ENST00000380667.6
ENST00000545497.5
ENST00000486514.5
basonuclin 2
chr17_-_41027198 0.12 ENST00000361883.6
keratin associated protein 1-5
chr19_-_58098203 0.10 ENST00000600845.1
ENST00000240727.10
ENST00000600897.5
ENST00000421612.6
ENST00000601063.1
ENST00000601144.6
zinc finger and SCAN domain containing 18
chr2_+_169069537 0.10 ENST00000428522.5
ENST00000450153.1
ENST00000674881.1
ENST00000421653.5
dehydrogenase/reductase 9
chr1_+_89524871 0.09 ENST00000639264.1
leucine rich repeat containing 8 VRAC subunit B
chr1_+_89524819 0.09 ENST00000439853.6
ENST00000330947.7
ENST00000449440.5
ENST00000640258.1
leucine rich repeat containing 8 VRAC subunit B
chr4_+_678189 0.09 ENST00000507804.1
myosin light chain 5
chr21_+_44646414 0.09 ENST00000334670.9
keratin associated protein 10-11
chr2_-_98936155 0.09 ENST00000428096.5
ENST00000397899.7
ENST00000420294.1
CRACD like
chr10_-_48493641 0.08 ENST00000417247.6
Rho GTPase activating protein 22
chr6_-_87095059 0.07 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr22_+_22375984 0.07 ENST00000390296.2
immunoglobulin lambda variable 5-45
chr11_+_68010281 0.07 ENST00000615463.4
ENST00000342456.11
aldehyde dehydrogenase 3 family member B1
chr22_-_30387078 0.06 ENST00000215798.10
ring finger protein 215
chr9_-_16870662 0.06 ENST00000380672.9
basonuclin 2
chr3_+_141386862 0.06 ENST00000513258.5
zinc finger and BTB domain containing 38
chr5_+_112976702 0.06 ENST00000515408.5
ENST00000513585.6
decapping mRNA 2
chr7_-_100896123 0.06 ENST00000428317.7
acetylcholinesterase (Cartwright blood group)
chr6_-_35688907 0.06 ENST00000539068.5
ENST00000357266.9
FKBP prolyl isomerase 5
chr17_-_41065879 0.05 ENST00000394015.3
keratin associated protein 2-4
chr16_+_30985181 0.05 ENST00000262520.10
ENST00000297679.10
ENST00000562932.5
ENST00000574447.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr16_+_55479188 0.05 ENST00000219070.9
matrix metallopeptidase 2
chr13_-_44474296 0.05 ENST00000611198.4
TSC22 domain family member 1
chr1_-_20119527 0.05 ENST00000375105.8
ENST00000617227.1
phospholipase A2 group IID
chr17_+_18377769 0.05 ENST00000399134.5
envoplakin like
chr5_+_112976757 0.05 ENST00000389063.3
decapping mRNA 2
chr17_+_41226648 0.05 ENST00000377721.3
keratin associated protein 9-2
chr9_-_124500986 0.05 ENST00000373587.3
nuclear receptor subfamily 5 group A member 1
chr11_+_116830529 0.05 ENST00000630701.1
apolipoprotein C3
chr11_-_134253248 0.04 ENST00000392595.6
ENST00000352327.5
ENST00000341541.8
ENST00000392594.7
thymocyte nuclear protein 1
chrX_-_154805386 0.04 ENST00000393531.5
ENST00000369534.8
ENST00000453245.5
ENST00000428488.1
ENST00000369531.1
membrane palmitoylated protein 1
chr2_+_135741717 0.04 ENST00000415164.5
UBX domain protein 4
chr20_+_56629296 0.04 ENST00000201031.3
transcription factor AP-2 gamma
chr19_+_44905785 0.04 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr20_-_44210697 0.04 ENST00000255174.3
oxidative stress responsive serine rich 1
chr1_+_16022004 0.04 ENST00000439316.6
chloride voltage-gated channel Ka
chr17_-_41034871 0.04 ENST00000344363.7
keratin associated protein 1-3
chr2_+_79120474 0.04 ENST00000233735.2
regenerating family member 1 alpha
chr22_+_43923755 0.04 ENST00000423180.2
ENST00000216180.8
patatin like phospholipase domain containing 3
chr1_+_18631513 0.04 ENST00000400661.3
paired box 7
chr5_-_141673160 0.04 ENST00000513878.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr22_+_39014249 0.04 ENST00000361441.5
apolipoprotein B mRNA editing enzyme catalytic subunit 3C
chrX_-_154805516 0.04 ENST00000413259.7
membrane palmitoylated protein 1
chr15_-_40564980 0.04 ENST00000558750.5
ENST00000561011.5
ENST00000560305.5
ENST00000559911.5
ENST00000558113.5
ENST00000559103.1
ENST00000558918.1
ENST00000416810.7
ENST00000558871.1
ENST00000358005.7
ENST00000625629.2
coiled-coil domain containing 32
chr1_+_18631006 0.04 ENST00000375375.7
paired box 7
chr5_+_157743703 0.04 ENST00000286307.6
LSM11, U7 small nuclear RNA associated
chr6_-_168319762 0.04 ENST00000366795.4
dishevelled binding antagonist of beta catenin 2
chr6_-_168319691 0.03 ENST00000610183.1
ENST00000607983.1
dishevelled binding antagonist of beta catenin 2
chr12_+_4809176 0.03 ENST00000280684.3
potassium voltage-gated channel subfamily A member 6
chr10_-_62268837 0.03 ENST00000373789.8
rhotekin 2
chr21_+_43728851 0.03 ENST00000327574.4
pyridoxal kinase
chr22_-_24226112 0.03 ENST00000425408.5
gamma-glutamyltransferase 5
chr11_+_68010339 0.03 ENST00000617288.4
aldehyde dehydrogenase 3 family member B1
chr5_-_127073467 0.03 ENST00000607731.5
ENST00000509733.7
ENST00000296662.10
ENST00000535381.6
chromosome 5 open reading frame 63
chr1_+_16043736 0.03 ENST00000619181.4
chloride voltage-gated channel Kb
chr10_-_33335074 0.03 ENST00000432372.6
neuropilin 1
chr14_+_57268963 0.03 ENST00000261558.8
adaptor related protein complex 5 subunit mu 1
chr15_+_41621134 0.03 ENST00000566718.6
MAX dimerization protein MGA
chr16_+_28846674 0.03 ENST00000322610.12
SH2B adaptor protein 1
chr21_+_30396030 0.03 ENST00000355459.4
keratin associated protein 13-1
chr19_-_3063101 0.03 ENST00000221561.12
TLE family member 5, transcriptional modulator
chr1_+_111449442 0.03 ENST00000369722.8
ENST00000483994.1
ATP synthase peripheral stalk-membrane subunit b
chr19_-_3062772 0.03 ENST00000586742.5
TLE family member 5, transcriptional modulator
chr1_+_61404076 0.03 ENST00000357977.5
nuclear factor I A
chr7_-_100895878 0.03 ENST00000419336.6
ENST00000241069.11
ENST00000411582.4
ENST00000302913.8
acetylcholinesterase (Cartwright blood group)
chr12_-_58920465 0.03 ENST00000320743.8
leucine rich repeats and immunoglobulin like domains 3
chr1_+_65147514 0.03 ENST00000545314.5
adenylate kinase 4
chr14_+_54567100 0.03 ENST00000554335.6
sterile alpha motif domain containing 4A
chr1_-_211133945 0.03 ENST00000640044.1
ENST00000640566.1
potassium voltage-gated channel subfamily H member 1
chr3_-_86991135 0.03 ENST00000398399.7
vestigial like family member 3
chr11_+_62242232 0.03 ENST00000244926.4
secretoglobin family 1D member 2
chr4_-_174829212 0.03 ENST00000340217.5
ENST00000274093.8
glycine receptor alpha 3
chr19_-_3062464 0.02 ENST00000327141.9
TLE family member 5, transcriptional modulator
chr10_+_113709261 0.02 ENST00000672138.1
ENST00000452490.3
caspase 7
chr19_+_13024917 0.02 ENST00000587260.1
nuclear factor I X
chr19_+_41003946 0.02 ENST00000593831.1
cytochrome P450 family 2 subfamily B member 6
chr1_+_65147657 0.02 ENST00000546702.5
adenylate kinase 4
chr1_+_16021871 0.02 ENST00000375692.5
chloride voltage-gated channel Ka
chr1_+_16043776 0.02 ENST00000375679.9
chloride voltage-gated channel Kb
chr3_-_71305986 0.02 ENST00000647614.1
forkhead box P1
chr11_-_73598183 0.02 ENST00000064778.8
family with sequence similarity 168 member A
chr1_+_16022030 0.02 ENST00000331433.5
chloride voltage-gated channel Ka
chr11_-_40294089 0.02 ENST00000278198.2
leucine rich repeat containing 4C
chr11_-_73598067 0.02 ENST00000450446.6
ENST00000356467.5
family with sequence similarity 168 member A
chr4_+_88523810 0.02 ENST00000512194.2
ENST00000598772.1
ENST00000597259.2
HECT and RLD domain containing E3 ubiquitin protein ligase 3
PIGY divergent transcript
chr4_-_40630588 0.02 ENST00000514014.1
RNA binding motif protein 47
chr13_-_28495079 0.02 ENST00000615840.4
ENST00000282397.9
ENST00000541932.5
ENST00000539099.1
ENST00000639477.1
fms related receptor tyrosine kinase 1
chr14_+_64504574 0.02 ENST00000358738.3
zinc finger and BTB domain containing 1
chr16_-_695946 0.02 ENST00000562563.1
F-box and leucine rich repeat protein 16
chr2_+_88885397 0.02 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr2_+_230878139 0.02 ENST00000620962.1
integral membrane protein 2C
chr20_-_32743406 0.02 ENST00000474815.2
ENST00000446419.6
ENST00000278980.11
ENST00000642484.1
ENST00000646357.1
COMM domain containing 7
novel protein
chr17_+_77453993 0.02 ENST00000592951.5
septin 9
chr10_-_33334898 0.02 ENST00000395995.5
neuropilin 1
chr6_-_34248989 0.02 ENST00000481533.5
ENST00000468145.1
ENST00000476320.6
ENST00000394990.8
small integral membrane protein 29
chr17_-_55732074 0.02 ENST00000575734.5
transmembrane protein 100
chrX_-_47574738 0.02 ENST00000640721.1
synapsin I
chr3_-_71306012 0.02 ENST00000649431.1
ENST00000610810.5
forkhead box P1
chr1_+_2556361 0.02 ENST00000355716.5
TNF receptor superfamily member 14
chr17_+_8339837 0.02 ENST00000328248.7
ENST00000584943.1
outer dense fiber of sperm tails 4
chr10_-_33334625 0.02 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr1_-_1779976 0.02 ENST00000378625.5
NAD kinase
chr17_+_62627628 0.02 ENST00000303375.10
mannose receptor C type 2
chr10_+_96043394 0.02 ENST00000403870.7
ENST00000265992.9
ENST00000465148.3
cyclin J
chr16_+_721596 0.02 ENST00000568916.1
adenine nucleotide translocase lysine methyltransferase
chr17_+_45999250 0.02 ENST00000537309.1
saitohin
chr7_+_107744134 0.02 ENST00000222597.6
ENST00000440859.8
ENST00000415884.6
Cbl proto-oncogene like 1
chr12_-_25648544 0.02 ENST00000540106.5
ENST00000445693.5
ENST00000545543.1
lamin tail domain containing 1
chr7_-_103149182 0.02 ENST00000417955.5
ENST00000341533.8
ENST00000425379.1
N-acyl phosphatidylethanolamine phospholipase D
chr6_-_34249102 0.02 ENST00000636500.1
small integral membrane protein 29
chr10_-_62268685 0.02 ENST00000395260.3
rhotekin 2
chr21_+_44697427 0.01 ENST00000618832.1
keratin associated protein 10-12
chr21_+_44600597 0.01 ENST00000609664.2
keratin associated protein 10-7
chrX_+_13689171 0.01 ENST00000618931.2
RAB9A, member RAS oncogene family
chr22_-_23580223 0.01 ENST00000249053.3
ENST00000330377.3
ENST00000438703.1
immunoglobulin lambda like polypeptide 1
chr4_+_24795560 0.01 ENST00000382120.4
superoxide dismutase 3
chr17_-_10036741 0.01 ENST00000585266.5
growth arrest specific 7
chr12_-_124567464 0.01 ENST00000458234.5
nuclear receptor corepressor 2
chr15_+_80060113 0.01 ENST00000618205.4
zinc finger AN1-type containing 6
chr1_+_226223618 0.01 ENST00000542034.5
ENST00000366810.6
Mix paired-like homeobox
chrX_+_13689116 0.01 ENST00000464506.2
ENST00000243325.6
RAB9A, member RAS oncogene family
chr19_+_38390055 0.01 ENST00000587947.5
ENST00000338502.8
sprouty related EVH1 domain containing 3
chr6_+_31572279 0.01 ENST00000418386.3
lymphotoxin alpha
chr4_-_108168950 0.01 ENST00000379951.6
lymphoid enhancer binding factor 1
chr15_+_80059568 0.01 ENST00000613266.4
ENST00000561060.5
zinc finger AN1-type containing 6
chr19_-_45639104 0.01 ENST00000586770.5
ENST00000591721.5
ENST00000245925.8
ENST00000590043.5
ENST00000589876.5
EMAP like 2
chr1_-_211134135 0.01 ENST00000638983.1
ENST00000271751.10
ENST00000639952.1
novel protein
potassium voltage-gated channel subfamily H member 1
chr1_+_161118083 0.01 ENST00000368009.7
ENST00000368007.8
ENST00000392190.9
ENST00000368008.5
nitrilase 1
chr4_-_108168919 0.01 ENST00000265165.6
lymphoid enhancer binding factor 1
chr17_+_30477362 0.01 ENST00000225724.9
ENST00000451249.7
ENST00000467337.6
ENST00000581721.5
ENST00000414833.2
golgi SNAP receptor complex member 1
chr6_+_28141830 0.01 ENST00000330236.7
zinc finger with KRAB and SCAN domains 8
chr15_+_80059635 0.01 ENST00000559157.5
zinc finger AN1-type containing 6
chr1_+_23793649 0.01 ENST00000374501.1
lysophospholipase 2
chr17_-_58531941 0.01 ENST00000581607.1
ENST00000317256.10
ENST00000426861.5
ENST00000580809.5
ENST00000577729.5
ENST00000583291.1
septin 4
chr17_-_41047267 0.01 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr14_+_38207893 0.01 ENST00000267377.3
somatostatin receptor 1
chr6_+_31571957 0.01 ENST00000454783.5
lymphotoxin alpha
chr3_+_32817990 0.01 ENST00000383763.6
tripartite motif containing 71
chr15_-_83067199 0.01 ENST00000261721.9
BTB domain containing 1
chr7_-_150800533 0.01 ENST00000434545.5
transmembrane protein 176B
chr7_-_103149056 0.01 ENST00000465647.6
ENST00000418294.1
N-acyl phosphatidylethanolamine phospholipase D
chr12_+_26938454 0.01 ENST00000229395.8
ENST00000544111.5
ENST00000546072.5
ENST00000327214.5
FGFR1 oncogene partner 2
chr15_+_81296913 0.01 ENST00000394652.6
interleukin 16
chr21_-_44592505 0.01 ENST00000400368.1
keratin associated protein 10-6
chr4_-_88523740 0.01 ENST00000273968.5
ENST00000527353.2
PIGY upstream reading frame
phosphatidylinositol glycan anchor biosynthesis class Y
chr1_-_89175997 0.01 ENST00000294671.3
ENST00000650452.1
guanylate binding protein 7
chr4_+_118685373 0.01 ENST00000388822.10
ENST00000508801.1
methyltransferase like 14
chr8_-_81842192 0.01 ENST00000353788.8
ENST00000520618.5
ENST00000518183.5
ENST00000396330.6
ENST00000519119.5
sorting nexin 16
chr6_-_168075831 0.01 ENST00000440994.6
FERM domain containing 1
chr17_-_7043906 0.01 ENST00000308009.5
ENST00000447225.1
solute carrier family 16 member 11
chr7_-_108240049 0.01 ENST00000379022.8
neuronal cell adhesion molecule
chr16_-_11392065 0.01 ENST00000599216.5
novel lipoprotein amino terminal region containing protein
chr17_-_7044091 0.01 ENST00000574600.3
ENST00000662352.3
ENST00000673828.2
solute carrier family 16 member 11
chr5_+_141135199 0.01 ENST00000231134.8
ENST00000623915.1
protocadherin beta 5
chr11_-_22625804 0.01 ENST00000327470.6
FA complementation group F
chr14_-_57268810 0.01 ENST00000413566.6
ENST00000340918.11
ENST00000621441.5
exocyst complex component 5
chr21_+_44697172 0.01 ENST00000400365.3
keratin associated protein 10-12
chr5_+_153491174 0.01 ENST00000521843.6
glutamate ionotropic receptor AMPA type subunit 1
chr8_-_81841958 0.01 ENST00000519817.5
ENST00000521773.5
ENST00000523757.5
ENST00000345957.9
sorting nexin 16
chr17_-_64130813 0.01 ENST00000606895.2
endoplasmic reticulum to nucleus signaling 1
chr15_+_84980440 0.01 ENST00000310298.8
ENST00000557957.5
phosphodiesterase 8A
chr1_+_15438435 0.01 ENST00000375943.6
ENST00000375949.5
chymotrypsin C
chrX_-_70931089 0.00 ENST00000374299.8
ENST00000298085.4
solute carrier family 7 member 3
chr6_-_35688935 0.00 ENST00000542713.1
FKBP prolyl isomerase 5
chr10_-_73495966 0.00 ENST00000342558.3
ENST00000360663.10
ENST00000394828.6
ENST00000394829.6
protein phosphatase 3 catalytic subunit beta
chr7_-_73842508 0.00 ENST00000297873.9
methyltransferase like 27
chr19_+_36604817 0.00 ENST00000423582.5
zinc finger protein 382
chr4_+_6269831 0.00 ENST00000503569.5
ENST00000673991.1
ENST00000682275.1
ENST00000226760.5
wolframin ER transmembrane glycoprotein
chr19_-_2740001 0.00 ENST00000545664.5
ENST00000269740.9
ENST00000589363.5
ENST00000455372.2
solute carrier family 39 member 3
chrY_+_5000226 0.00 ENST00000333703.8
ENST00000622698.4
ENST00000621505.1
protocadherin 11 Y-linked
chr3_+_52420955 0.00 ENST00000465863.1
PHD finger protein 7
chr11_-_2171805 0.00 ENST00000381178.5
ENST00000381175.5
ENST00000333684.9
ENST00000352909.8
tyrosine hydroxylase
chr12_+_5432101 0.00 ENST00000423158.4
neurotrophin 3
chr3_+_49020443 0.00 ENST00000326912.8
NADH:ubiquinone oxidoreductase complex assembly factor 3
chr12_-_54588636 0.00 ENST00000257905.13
protein phosphatase 1 regulatory inhibitor subunit 1A
chr17_-_69060906 0.00 ENST00000495634.5
ENST00000453985.6
ENST00000340001.9
ENST00000585714.1
ATP binding cassette subfamily A member 9
chr11_+_15073562 0.00 ENST00000533448.1
ENST00000324229.11
calcitonin related polypeptide beta
chr19_+_35449584 0.00 ENST00000246549.2
free fatty acid receptor 2
chr22_+_29306582 0.00 ENST00000616432.4
ENST00000416823.1
ENST00000428622.1
growth arrest specific 2 like 1
chr11_-_62921339 0.00 ENST00000306960.4
cholinergic receptor muscarinic 1
chr17_-_58544315 0.00 ENST00000671766.1
ENST00000672673.2
ENST00000321691.3
septin 4
chr10_-_69416323 0.00 ENST00000619173.4
tachykinin receptor 2
chr20_+_33031648 0.00 ENST00000349552.1
BPI fold containing family B member 6
chr18_+_63702958 0.00 ENST00000544088.6
serpin family B member 11
chr14_+_35826298 0.00 ENST00000216807.12
BRMS1 like transcriptional repressor
chr11_-_46121397 0.00 ENST00000676320.1
PHD finger protein 21A

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.0 0.1 GO:0072061 inner medullary collecting duct development(GO:0072061) negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0021649 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.0 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.0 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)