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Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ZNF423

Z-value: 0.73

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Transcription factors associated with ZNF423

Gene Symbol Gene ID Gene Info
ZNF423
ENSG00000102935.12 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF423hg38_v1_chr16_-_49664225_49664298,
hg38_v1_chr16_-_49856105_49856119		-0.108.1e-01Click!

Activity profile of ZNF423 motif

Sorted Z-values of ZNF423 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_53480619 1.02 ENST00000396947.7
ENST00000256759.8
FST
follistatin
chr7_-_44225893 0.93 ENST00000425809.5
CAMK2B
calcium/calmodulin dependent protein kinase II beta
chr6_+_30884063 0.57 ENST00000511510.5
ENST00000376569.7
ENST00000376570.8
ENST00000504927.5
DDR1
discoidin domain receptor tyrosine kinase 1
chr12_-_54385727 0.47 ENST00000551109.5
ENST00000546970.5
ZNF385A
zinc finger protein 385A
chr11_+_60924452 0.46 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
TMEM132A
transmembrane protein 132A
chr16_+_2988256 0.43 ENST00000573315.2
LINC00514
long intergenic non-protein coding RNA 514
chr5_+_69492767 0.41 ENST00000681041.1
ENST00000680098.1
ENST00000680784.1
ENST00000396442.7
ENST00000681895.1
OCLN
occludin
chr9_+_113876282 0.41 ENST00000374126.9
ENST00000615615.4
ENST00000288466.11
ZNF618
zinc finger protein 618
chr7_+_20330893 0.40 ENST00000222573.5
ITGB8
integrin subunit beta 8
chr7_+_20330678 0.36 ENST00000537992.5
ITGB8
integrin subunit beta 8
chr11_-_44950867 0.36 ENST00000528290.5
ENST00000525680.6
ENST00000530035.5
ENST00000527685.5
TP53I11
tumor protein p53 inducible protein 11
chr1_-_32901330 0.36 ENST00000329151.5
ENST00000373463.8
TMEM54
transmembrane protein 54
chr11_-_44950839 0.33 ENST00000395648.7
ENST00000531928.6
TP53I11
tumor protein p53 inducible protein 11
chr8_-_79767843 0.33 ENST00000337919.9
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr11_+_45922640 0.32 ENST00000401752.6
ENST00000325468.9
LARGE2
LARGE xylosyl- and glucuronyltransferase 2
chr19_-_11578937 0.32 ENST00000592659.1
ENST00000592828.6
ENST00000218758.9
ENST00000412435.6
ACP5
acid phosphatase 5, tartrate resistant
chr8_-_79767462 0.30 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
HEY1
hes related family bHLH transcription factor with YRPW motif 1
chr16_+_2964216 0.30 ENST00000572045.5
ENST00000571007.5
ENST00000575885.5
ENST00000303746.10
ENST00000319500.10
KREMEN2
kringle containing transmembrane protein 2
chr16_+_3046552 0.29 ENST00000336577.9
MMP25
matrix metallopeptidase 25
chr7_-_19145306 0.29 ENST00000275461.3
FERD3L
Fer3 like bHLH transcription factor
chr11_-_44950151 0.28 ENST00000533940.5
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr9_+_109780179 0.27 ENST00000314527.9
PALM2AKAP2
PALM2 and AKAP2 fusion
chr17_-_29180359 0.26 ENST00000531253.5
ENST00000628822.2
MYO18A
myosin XVIIIA
chrX_-_48971829 0.26 ENST00000218176.4
KCND1
potassium voltage-gated channel subfamily D member 1
chr17_-_29180377 0.26 ENST00000527372.7
MYO18A
myosin XVIIIA
chr9_+_98807619 0.26 ENST00000375011.4
GALNT12
polypeptide N-acetylgalactosaminyltransferase 12
chr8_-_42377227 0.25 ENST00000220812.3
DKK4
dickkopf WNT signaling pathway inhibitor 4
chrX_-_51496572 0.24 ENST00000375992.4
NUDT11
nudix hydrolase 11
chr16_+_27313879 0.23 ENST00000562142.5
ENST00000561742.5
ENST00000543915.6
ENST00000395762.7
ENST00000563002.5
IL4R
interleukin 4 receptor
chr9_-_39239174 0.22 ENST00000358144.6
CNTNAP3
contactin associated protein family member 3
chr16_-_11587450 0.20 ENST00000571688.5
LITAF
lipopolysaccharide induced TNF factor
chr5_+_171309239 0.19 ENST00000296921.6
TLX3
T cell leukemia homeobox 3
chr5_+_136049513 0.19 ENST00000514554.5
TGFBI
transforming growth factor beta induced
chr12_+_109713817 0.18 ENST00000538780.2
FAM222A
family with sequence similarity 222 member A
chr16_-_11587162 0.18 ENST00000570904.5
ENST00000574701.5
LITAF
lipopolysaccharide induced TNF factor
chr19_+_45251249 0.18 ENST00000262891.9
ENST00000300843.8
MARK4
microtubule affinity regulating kinase 4
chr2_+_27496830 0.18 ENST00000264717.7
GCKR
glucokinase regulator
chr6_+_33621313 0.18 ENST00000605930.3
ITPR3
inositol 1,4,5-trisphosphate receptor type 3
chr19_+_45251363 0.18 ENST00000620044.4
MARK4
microtubule affinity regulating kinase 4
chr3_-_196082078 0.17 ENST00000360110.9
ENST00000392396.7
ENST00000420415.5
TFRC
transferrin receptor
chr16_-_70685975 0.17 ENST00000338779.11
MTSS2
MTSS I-BAR domain containing 2
chr5_-_176630364 0.16 ENST00000310112.7
SNCB
synuclein beta
chr10_+_84173793 0.16 ENST00000372126.4
C10orf99
chromosome 10 open reading frame 99
chr6_+_109440695 0.16 ENST00000258052.8
SMPD2
sphingomyelin phosphodiesterase 2
chr3_+_6861107 0.15 ENST00000357716.9
ENST00000486284.5
ENST00000389336.8
GRM7
glutamate metabotropic receptor 7
chr12_+_7189582 0.15 ENST00000266563.9
ENST00000543974.5
PEX5
peroxisomal biogenesis factor 5
chr10_+_133527355 0.15 ENST00000252945.8
ENST00000421586.5
ENST00000418356.1
CYP2E1
cytochrome P450 family 2 subfamily E member 1
chr10_+_125896549 0.15 ENST00000368693.6
FANK1
fibronectin type III and ankyrin repeat domains 1
chr5_-_176630517 0.15 ENST00000393693.7
ENST00000614675.4
SNCB
synuclein beta
chr12_+_7189845 0.14 ENST00000412720.6
ENST00000396637.7
PEX5
peroxisomal biogenesis factor 5
chr4_-_119627631 0.14 ENST00000264805.9
PDE5A
phosphodiesterase 5A
chr6_-_142147122 0.14 ENST00000258042.2
NMBR
neuromedin B receptor
chr1_-_203086001 0.14 ENST00000241651.5
MYOG
myogenin
chr12_+_7189675 0.14 ENST00000675855.1
ENST00000434354.6
ENST00000544456.5
ENST00000545574.5
ENST00000420616.6
PEX5
peroxisomal biogenesis factor 5
chr2_+_134254065 0.14 ENST00000281923.4
MGAT5
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr6_-_109440504 0.13 ENST00000520723.5
ENST00000518648.1
ENST00000417394.6
ENST00000521072.7
PPIL6
peptidylprolyl isomerase like 6
chr7_-_100656384 0.13 ENST00000461605.1
ENST00000160382.10
ACTL6B
actin like 6B
chr19_+_48393657 0.13 ENST00000263269.4
GRIN2D
glutamate ionotropic receptor NMDA type subunit 2D
chr12_+_50057548 0.13 ENST00000228468.8
ENST00000447966.7
ASIC1
acid sensing ion channel subunit 1
chr22_-_37427433 0.12 ENST00000452946.1
ENST00000402918.7
ELFN2
ELFN2
extracellular leucine rich repeat and fibronectin type III domain containing 2
extracellular leucine rich repeat and fibronectin type III domain containing 2
chr6_-_35512863 0.12 ENST00000428978.1
ENST00000614066.4
ENST00000322263.8
TULP1
TUB like protein 1
chr20_+_31475278 0.12 ENST00000201979.3
REM1
RRAD and GEM like GTPase 1
chr19_-_42242526 0.11 ENST00000222330.8
ENST00000676537.1
GSK3A
glycogen synthase kinase 3 alpha
chr4_-_165112852 0.11 ENST00000505095.1
ENST00000306480.11
TMEM192
transmembrane protein 192
chr19_-_35900532 0.11 ENST00000396901.5
ENST00000641389.2
ENST00000585925.7
NFKBID
NFKB inhibitor delta
chr14_-_93115869 0.11 ENST00000556603.6
ENST00000354313.7
ENST00000267615.11
ITPK1
inositol-tetrakisphosphate 1-kinase
chr12_-_57129001 0.10 ENST00000556155.5
STAT6
signal transducer and activator of transcription 6
chr11_-_61891381 0.10 ENST00000525588.5
FADS3
fatty acid desaturase 3
chr14_-_93115812 0.10 ENST00000553452.5
ITPK1
inositol-tetrakisphosphate 1-kinase
chr8_+_30384511 0.10 ENST00000339877.8
ENST00000320203.8
ENST00000287771.9
ENST00000397323.9
RBPMS
RNA binding protein, mRNA processing factor
chr15_-_41230697 0.10 ENST00000314992.9
ENST00000558396.1
ENST00000458580.7
EXD1
exonuclease 3'-5' domain containing 1
chr20_+_23035312 0.10 ENST00000255008.5
SSTR4
somatostatin receptor 4
chr19_-_12881460 0.10 ENST00000592506.1
DNASE2
deoxyribonuclease 2, lysosomal
chr10_-_75099489 0.10 ENST00000472493.6
ENST00000478873.7
ENST00000605915.5
DUSP13
dual specificity phosphatase 13
chr17_+_79024142 0.10 ENST00000579760.6
ENST00000339142.6
C1QTNF1
C1q and TNF related 1
chr19_-_4066892 0.09 ENST00000322357.9
ZBTB7A
zinc finger and BTB domain containing 7A
chr2_+_62705644 0.09 ENST00000427809.5
ENST00000405482.5
ENST00000431489.6
EHBP1
EH domain binding protein 1
chr17_+_79024243 0.09 ENST00000311661.4
C1QTNF1
C1q and TNF related 1
chr19_-_11481044 0.09 ENST00000359227.8
ELAVL3
ELAV like RNA binding protein 3
chr4_-_119628007 0.09 ENST00000420633.1
ENST00000394439.5
PDE5A
phosphodiesterase 5A
chr7_-_103989649 0.09 ENST00000428762.6
RELN
reelin
chr10_-_119536533 0.09 ENST00000392865.5
RGS10
regulator of G protein signaling 10
chr9_-_128724088 0.09 ENST00000406904.2
ENST00000452105.5
ENST00000372667.9
ENST00000372663.9
ZDHHC12
zinc finger DHHC-type palmitoyltransferase 12
chr6_-_35512882 0.08 ENST00000229771.11
TULP1
TUB like protein 1
chr6_+_11093753 0.08 ENST00000416247.4
SMIM13
small integral membrane protein 13
chr19_-_49867251 0.07 ENST00000631020.2
ENST00000596014.5
ENST00000636994.1
PNKP
polynucleotide kinase 3'-phosphatase
chr19_+_41264345 0.07 ENST00000378215.8
ENST00000392006.8
ENST00000617774.1
ENST00000602130.5
ENST00000617305.4
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U like 1
chr3_+_122795039 0.07 ENST00000261038.6
SLC49A4
solute carrier family 49 member 4
chr21_-_17612842 0.07 ENST00000339775.10
ENST00000348354.7
BTG3
BTG anti-proliferation factor 3
chr1_+_1512137 0.07 ENST00000378756.8
ENST00000378755.9
ATAD3A
ATPase family AAA domain containing 3A
chr16_+_71358713 0.06 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
CALB2
calbindin 2
chr10_+_112950240 0.06 ENST00000627217.3
ENST00000534894.5
ENST00000538897.5
ENST00000536810.5
ENST00000355995.8
ENST00000542695.5
ENST00000543371.5
TCF7L2
transcription factor 7 like 2
chr19_+_4279285 0.06 ENST00000599689.1
SHD
Src homology 2 domain containing transforming protein D
chr9_-_16870662 0.06 ENST00000380672.9
BNC2
basonuclin 2
chr1_-_101996919 0.06 ENST00000370103.9
OLFM3
olfactomedin 3
chr3_-_52897541 0.06 ENST00000355083.11
ENST00000504329.1
STIMATE
STIMATE-MUSTN1
STIM activating enhancer
STIMATE-MUSTN1 readthrough
chr5_+_151020438 0.06 ENST00000622181.4
ENST00000614343.4
ENST00000388825.9
ENST00000521650.5
ENST00000517973.1
GPX3
glutathione peroxidase 3
chr9_-_37904085 0.06 ENST00000377716.6
ENST00000242275.7
SLC25A51
solute carrier family 25 member 51
chr3_+_184338826 0.06 ENST00000453072.5
FAM131A
family with sequence similarity 131 member A
chr19_-_55599493 0.05 ENST00000221665.5
ENST00000592585.1
FIZ1
FLT3 interacting zinc finger 1
chr12_-_118372883 0.05 ENST00000542532.5
ENST00000392533.8
TAOK3
TAO kinase 3
chr11_-_30586866 0.05 ENST00000528686.2
MPPED2
metallophosphoesterase domain containing 2
chr19_+_45079195 0.05 ENST00000591607.1
ENST00000591747.5
ENST00000270257.9
ENST00000391951.2
ENST00000587566.5
GEMIN7
MARK4
gem nuclear organelle associated protein 7
microtubule affinity regulating kinase 4
chr17_-_81239025 0.05 ENST00000637944.2
TEPSIN
TEPSIN adaptor related protein complex 4 accessory protein
chr8_+_22165358 0.05 ENST00000306349.13
ENST00000306385.10
BMP1
bone morphogenetic protein 1
chr11_-_107858777 0.05 ENST00000525815.6
SLC35F2
solute carrier family 35 member F2
chr19_+_4279247 0.05 ENST00000543264.7
SHD
Src homology 2 domain containing transforming protein D
chr11_-_30586344 0.05 ENST00000358117.10
MPPED2
metallophosphoesterase domain containing 2
chrX_+_137566119 0.05 ENST00000287538.10
ZIC3
Zic family member 3
chr1_+_53062052 0.05 ENST00000395871.7
ENST00000673702.1
ENST00000673956.1
ENST00000312553.10
ENST00000371500.8
ENST00000618387.1
PODN
podocan
chr1_+_1471751 0.04 ENST00000673477.1
ENST00000308647.8
ATAD3B
ATPase family AAA domain containing 3B
chr11_-_1036706 0.04 ENST00000421673.7
MUC6
mucin 6, oligomeric mucus/gel-forming
chr4_-_20984011 0.04 ENST00000382149.9
KCNIP4
potassium voltage-gated channel interacting protein 4
chr12_-_49707220 0.04 ENST00000550488.5
FMNL3
formin like 3
chr7_-_27180230 0.04 ENST00000396344.4
HOXA10
homeobox A10
chr1_+_26317950 0.03 ENST00000374213.3
CD52
CD52 molecule
chr15_-_58933668 0.03 ENST00000380516.7
SLTM
SAFB like transcription modulator
chr7_+_151051201 0.03 ENST00000490540.1
ASIC3
acid sensing ion channel subunit 3
chr11_-_61891534 0.03 ENST00000278829.7
FADS3
fatty acid desaturase 3
chr17_-_44376169 0.03 ENST00000587295.5
ITGA2B
integrin subunit alpha 2b
chr6_+_42929430 0.03 ENST00000372836.5
CNPY3
canopy FGF signaling regulator 3
chr9_-_96619783 0.03 ENST00000375241.6
CDC14B
cell division cycle 14B
chr12_+_52079700 0.02 ENST00000546390.2
SMIM41
small integral membrane protein 41
chr6_+_142147162 0.02 ENST00000452973.6
ENST00000620996.4
ENST00000367621.1
ENST00000367630.9
VTA1
vesicle trafficking 1
chr7_+_29194757 0.02 ENST00000222792.11
CHN2
chimerin 2
chr1_-_204152010 0.02 ENST00000367202.9
ETNK2
ethanolamine kinase 2
chr1_-_204151884 0.02 ENST00000367201.7
ETNK2
ethanolamine kinase 2
chr11_-_63015831 0.02 ENST00000430500.6
ENST00000336232.7
SLC22A8
solute carrier family 22 member 8
chr16_+_70114306 0.02 ENST00000288050.9
ENST00000398122.7
ENST00000568530.5
PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr3_+_32685128 0.02 ENST00000331889.10
ENST00000328834.9
CNOT10
CCR4-NOT transcription complex subunit 10
chr22_+_35257452 0.02 ENST00000420166.5
ENST00000216106.6
ENST00000455359.5
HMGXB4
HMG-box containing 4
chr11_-_63917129 0.02 ENST00000301459.5
RCOR2
REST corepressor 2
chr1_+_26993684 0.02 ENST00000522111.3
TRNP1
TMF1 regulated nuclear protein 1
chr3_-_69080350 0.02 ENST00000630585.1
ENST00000361055.9
ENST00000415609.6
ENST00000349511.8
UBA3
ubiquitin like modifier activating enzyme 3
chr13_-_46052712 0.01 ENST00000242848.8
ENST00000679008.1
ENST00000282007.7
ZC3H13
zinc finger CCCH-type containing 13
chr9_-_127980976 0.01 ENST00000373095.6
FAM102A
family with sequence similarity 102 member A
chr9_-_96619378 0.01 ENST00000375240.7
ENST00000463569.5
CDC14B
cell division cycle 14B
chr2_-_206086057 0.01 ENST00000403263.6
INO80D
INO80 complex subunit D
chr19_+_35533436 0.01 ENST00000222286.9
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr19_-_46714269 0.01 ENST00000600194.5
PRKD2
protein kinase D2
chr6_+_42929127 0.01 ENST00000394142.7
CNPY3
canopy FGF signaling regulator 3
chr16_+_283157 0.01 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
PDIA2
protein disulfide isomerase family A member 2
chr18_-_5543988 0.01 ENST00000341928.7
EPB41L3
erythrocyte membrane protein band 4.1 like 3
chr8_+_22165140 0.01 ENST00000397814.7
ENST00000354870.5
BMP1
bone morphogenetic protein 1
chr2_+_14632688 0.01 ENST00000331243.4
ENST00000295092.3
LRATD1
LRAT domain containing 1
chr19_-_15200902 0.01 ENST00000601011.1
ENST00000263388.7
NOTCH3
notch receptor 3
chr2_+_170929198 0.00 ENST00000234160.5
GORASP2
golgi reassembly stacking protein 2
chr19_-_56671746 0.00 ENST00000537055.4
ENST00000601659.1
ZNF835
zinc finger protein 835
chr12_+_57128656 0.00 ENST00000338962.8
LRP1
LDL receptor related protein 1
chr9_-_127897399 0.00 ENST00000542456.5
ENST00000373141.5
ST6GALNAC6
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF423

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0036304 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.2 0.5 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.5 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.4 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:1990834 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.1 1.0 GO:0051798 negative regulation of activin receptor signaling pathway(GO:0032926) positive regulation of hair follicle development(GO:0051798)
0.0 0.2 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.1 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.9 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:1901910 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.3 GO:0033504 floor plate development(GO:0033504)
0.0 0.4 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258) negative regulation of type B pancreatic cell development(GO:2000077)
0.0 0.2 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.8 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.3 GO:0060022 hard palate development(GO:0060022)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0035939 microsatellite binding(GO:0035939)
0.2 0.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.2 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.1 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 1.0 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0052845 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.2 GO:0070905 serine binding(GO:0070905)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.0 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction