Epithelial-Mesenchymal Transition, human (Scheel, 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
ZNF8 Links Ensembl NCBI GeneCards UniProt NextProt	ENSG00000278129.2	zinc finger protein 8

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ZNF8	hg38_v1_chr19_+_58278948_58278992	-0.74	3.5e-02	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_+_35248994 Show fit	0.63	ENST00000427250.5 ENST00000605618.6	LSR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lipolysis stimulated lipoprotein receptor
chr19_+_35248879 Show fit	0.60	ENST00000347609.8	LSR Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lipolysis stimulated lipoprotein receptor
chr3_-_57079287 Show fit	0.48	ENST00000338458.8 ENST00000468727.5	ARHGEF3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho guanine nucleotide exchange factor 3
chr19_-_55140922 Show fit	0.39	ENST00000589745.5	TNNT1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	troponin T1, slow skeletal type
chr1_-_54801290 Show fit	0.23	ENST00000371276.9	TTC22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tetratricopeptide repeat domain 22
chr6_+_18155399 Show fit	0.17	ENST00000650836.2 ENST00000449850.2 ENST00000297792.9	KDM1B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	lysine demethylase 1B
chrX_+_129779930 Show fit	0.15	ENST00000356892.4	SASH3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	SAM and SH3 domain containing 3
chr17_+_50508384 Show fit	0.12	ENST00000436259.6 ENST00000652471.1 ENST00000323776.11 ENST00000419930.2	MYCBPAP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	MYCBP associated protein
chr6_+_29723340 Show fit	0.10	ENST00000334668.8	HLA-F Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class I, F
chr7_+_48035511 Show fit	0.09	ENST00000420324.5 ENST00000539619.5 ENST00000435376.5 ENST00000430738.5 ENST00000348904.4	C7orf57 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 7 open reading frame 57
chr12_-_46268989 Show fit	0.09	ENST00000549049.5 ENST00000439706.5 ENST00000398637.10	SLC38A1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 38 member 1
chr6_+_29723421 Show fit	0.09	ENST00000259951.12 ENST00000434407.6	HLA-F Links Ensembl NCBI GeneCards UniProt NextProt Show fit	major histocompatibility complex, class I, F
chr2_-_171433950 Show fit	0.08	ENST00000375258.9 ENST00000442541.1 ENST00000392599.6	METTL8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	methyltransferase like 8
chr1_-_235128819 Show fit	0.07	ENST00000366607.5	TOMM20 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	translocase of outer mitochondrial membrane 20
chr11_+_13668653 Show fit	0.06	ENST00000354817.8	FAR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acyl-CoA reductase 1
chr9_+_32552305 Show fit	0.06	ENST00000451672.2 ENST00000644531.1	SMIM27 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small integral membrane protein 27
chr8_-_108248700 Show fit	0.06	ENST00000220849.10 ENST00000678937.1 ENST00000678901.1 ENST00000678243.1 ENST00000677674.1 ENST00000521297.2 ENST00000677272.1 ENST00000522352.6 ENST00000678042.1 ENST00000519627.2 ENST00000521440.6 ENST00000678773.1 ENST00000676698.1 ENST00000518345.2 ENST00000677447.1 ENST00000676548.1 ENST00000519030.6 ENST00000518442.5	EIF3E Links Ensembl NCBI GeneCards UniProt NextProt Show fit	eukaryotic translation initiation factor 3 subunit E
chr11_+_13668702 Show fit	0.06	ENST00000532701.1	FAR1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acyl-CoA reductase 1
chr6_+_116280098 Show fit	0.05	ENST00000643175.1 ENST00000452085.7	DSE Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dermatan sulfate epimerase
chr6_-_107459504 Show fit	0.05	ENST00000369037.9 ENST00000369031.4	PDSS2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	decaprenyl diphosphate synthase subunit 2
chr2_+_119431846 Show fit	0.05	ENST00000306406.5	TMEM37 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 37
chr2_+_197500371 Show fit	0.04	ENST00000409468.1 ENST00000233893.10	HSPE1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock protein family E (Hsp10) member 1
chr9_-_32552553 Show fit	0.04	ENST00000379858.1 ENST00000360538.7 ENST00000681750.1 ENST00000680198.1	TOPORS Links Ensembl NCBI GeneCards UniProt NextProt Show fit ENSG00000288684.1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase novel protein
chr1_-_54801161 Show fit	0.04	ENST00000371274.8	TTC22 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	tetratricopeptide repeat domain 22
chr17_+_35809474 Show fit	0.04	ENST00000604879.5 ENST00000603427.5 ENST00000603777.5 ENST00000605844.6 ENST00000604841.5	TAF15 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TATA-box binding protein associated factor 15
chr13_+_36819214 Show fit	0.03	ENST00000255476.3	RFXAP Links Ensembl NCBI GeneCards UniProt NextProt Show fit	regulatory factor X associated protein
chr15_+_84980440 Show fit	0.03	ENST00000310298.8 ENST00000557957.5	PDE8A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphodiesterase 8A
chr6_+_87407965 Show fit	0.03	ENST00000369562.9	CFAP206 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cilia and flagella associated protein 206
chr1_-_100249815 Show fit	0.03	ENST00000370131.3 ENST00000681617.1 ENST00000681780.1 ENST00000370132.8	DBT Links Ensembl NCBI GeneCards UniProt NextProt Show fit	dihydrolipoamide branched chain transacylase E2
chr7_+_118184105 Show fit	0.03	ENST00000424702.1	LSM8 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	LSM8 homolog, U6 small nuclear RNA associated
chr6_+_44246166 Show fit	0.02	ENST00000620073.4	HSP90AB1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	heat shock protein 90 alpha family class B member 1
chr4_+_185426234 Show fit	0.02	ENST00000511138.5 ENST00000511581.5 ENST00000378850.5	C4orf47 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 4 open reading frame 47
chr7_+_100706061 Show fit	0.02	ENST00000303151.5	POP7 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	POP7 homolog, ribonuclease P/MRP subunit
chr16_+_21953341 Show fit	0.02	ENST00000268379.9 ENST00000561553.5 ENST00000565331.5	UQCRC2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	ubiquinol-cytochrome c reductase core protein 2
chr6_-_26056460 Show fit	0.02	ENST00000343677.4	H1-2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	H1.2 linker histone, cluster member
chr10_+_988425 Show fit	0.02	ENST00000360803.9	GTPBP4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GTP binding protein 4
chr13_+_52455429 Show fit	0.02	ENST00000468284.1 ENST00000378034.7 ENST00000378037.9 ENST00000258607.10	CKAP2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	cytoskeleton associated protein 2
chr3_+_113838772 Show fit	0.02	ENST00000358160.9	GRAMD1C Links Ensembl NCBI GeneCards UniProt NextProt Show fit	GRAM domain containing 1C
chr6_-_116279837 Show fit	0.01	ENST00000368608.4	TSPYL1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	TSPY like 1
chr2_-_105329685 Show fit	0.01	ENST00000393359.7	TGFBRAP1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transforming growth factor beta receptor associated protein 1
chr7_+_45574358 Show fit	0.01	ENST00000297323.12	ADCY1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	adenylate cyclase 1
chr1_+_25338294 Show fit	0.01	ENST00000374358.5	TMEM50A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 50A
chr7_+_1709162 Show fit	0.01	ENST00000561626.3	ELFN1 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	extracellular leucine rich repeat and fibronectin type III domain containing 1
chr13_-_21176540 Show fit	0.01	ENST00000400018.7 ENST00000314759.6	SKA3 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	spindle and kinetochore associated complex subunit 3
chr7_-_75073844 Show fit	0.01	ENST00000614461.4 ENST00000618035.4	RCC1L Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RCC1 like
chr9_+_32551670 Show fit	0.01	ENST00000450093.3	SMIM27 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	small integral membrane protein 27
chrX_+_130401962 Show fit	0.01	ENST00000305536.11 ENST00000370947.1	RBMX2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif protein X-linked 2
chr9_+_93263948 Show fit	0.01	ENST00000448251.5	WNK2 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WNK lysine deficient protein kinase 2
chr2_+_189441460 Show fit	0.01	ENST00000314761.9 ENST00000631047.1	WDR75 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	WD repeat domain 75
chr2_+_171434196 Show fit	0.00	ENST00000375255.8 ENST00000539783.5	DCAF17 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	DDB1 and CUL4 associated factor 17
chr12_-_122266410 Show fit	0.00	ENST00000451053.3	VPS33A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	VPS33A core subunit of CORVET and HOPS complexes
chr8_+_26291758 Show fit	0.00	ENST00000522535.5 ENST00000665949.1	PPP2R2A Links Ensembl NCBI GeneCards UniProt NextProt Show fit	protein phosphatase 2 regulatory subunit Balpha
chr4_-_76148382 Show fit	0.00	ENST00000264883.8 ENST00000514987.5 ENST00000514901.5	NUP54 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	nucleoporin 54
chr17_-_28842727 Show fit	0.00	ENST00000583307.6 ENST00000581229.6 ENST00000582266.6 ENST00000577376.6 ENST00000577682.6 ENST00000581407.6 ENST00000341217.7 ENST00000583522.6	FAM222B Links Ensembl NCBI GeneCards UniProt NextProt Show fit	family with sequence similarity 222 member B
chr2_-_239400949 Show fit	0.00	ENST00000345617.7	HDAC4 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	histone deacetylase 4
chr12_+_52069967 Show fit	0.00	ENST00000336854.9 ENST00000550604.1 ENST00000553049.5 ENST00000548915.1	ATG101 Links Ensembl NCBI GeneCards UniProt NextProt Show fit	autophagy related 101

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.2	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.0	0.4	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.2	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0	0.1	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.0	0.2	GO:0034720	histone H3-K4 demethylation(GO:0034720)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.4	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	GO:0031014	troponin T binding(GO:0031014)
0.0	0.2	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0046979	TAP2 binding(GO:0046979)
0.0	0.1	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0	0.1	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway