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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for AGCAGCG

Z-value: 1.22

Motif logo

miRNA associated with seed AGCAGCG

NamemiRBASE accession
MIMAT0002874

Activity profile of AGCAGCG motif

Sorted Z-values of AGCAGCG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_27529705 1.25 ENST00000262244.6
MOB kinase activator 3B
chr8_+_94641145 1.20 ENST00000433389.8
ENST00000358397.9
epithelial splicing regulatory protein 1
chr12_+_4273751 0.97 ENST00000675880.1
ENST00000261254.8
cyclin D2
chr2_-_46462 0.76 ENST00000327669.5
family with sequence similarity 110 member C
chr3_-_13880059 0.71 ENST00000285018.5
Wnt family member 7A
chr2_-_121285194 0.67 ENST00000263707.6
transcription factor CP2 like 1
chr1_+_65147514 0.61 ENST00000545314.5
adenylate kinase 4
chr6_-_96837460 0.49 ENST00000229955.4
G protein-coupled receptor 63
chr8_+_28701487 0.47 ENST00000220562.9
exostosin like glycosyltransferase 3
chr1_-_47997348 0.46 ENST00000606738.3
TraB domain containing 2B
chr10_+_93893931 0.44 ENST00000371408.7
ENST00000427197.2
solute carrier family 35 member G1
chr17_+_32486975 0.38 ENST00000313401.4
cyclin dependent kinase 5 regulatory subunit 1
chr11_-_119729158 0.38 ENST00000264025.8
nectin cell adhesion molecule 1
chr8_-_42541898 0.36 ENST00000342228.7
solute carrier family 20 member 2
chr4_+_20251896 0.32 ENST00000504154.6
slit guidance ligand 2
chr2_-_72147819 0.32 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
cytochrome P450 family 26 subfamily B member 1
chr20_+_50731571 0.29 ENST00000371610.7
par-6 family cell polarity regulator beta
chr3_-_129688691 0.28 ENST00000432054.6
transmembrane and coiled-coil domain family 1
chr12_-_7936177 0.28 ENST00000544291.1
ENST00000075120.12
solute carrier family 2 member 3
chr7_+_30284574 0.27 ENST00000323037.5
zinc and ring finger 2
chr3_-_48188356 0.25 ENST00000351231.7
ENST00000437972.1
ENST00000302506.8
cell division cycle 25A
chr15_+_66386902 0.24 ENST00000307102.10
mitogen-activated protein kinase kinase 1
chr6_+_18387326 0.24 ENST00000259939.4
ring finger protein 144B
chr4_-_76023489 0.23 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr6_+_34889228 0.21 ENST00000360359.5
ENST00000649117.1
ENST00000650178.1
ankyrin repeat and sterile alpha motif domain containing 1A
chr4_-_98929092 0.21 ENST00000280892.10
ENST00000511644.5
ENST00000504432.5
ENST00000450253.7
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr12_-_7872843 0.20 ENST00000340749.9
ENST00000535295.5
ENST00000539234.5
solute carrier family 2 member 14
chr14_+_24398986 0.20 ENST00000382554.4
NYN domain and retroviral integrase containing
chr7_-_99144053 0.20 ENST00000361125.1
ENST00000361368.7
SMAD specific E3 ubiquitin protein ligase 1
chr10_-_118754956 0.19 ENST00000369151.8
CDK2 associated cullin domain 1
chr3_-_123884290 0.19 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
myosin light chain kinase
chr3_+_10816201 0.18 ENST00000454147.1
ENST00000254488.7
solute carrier family 6 member 11
chr6_+_15246054 0.18 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr22_-_41621014 0.17 ENST00000263256.7
desumoylating isopeptidase 1
chr12_+_57755060 0.16 ENST00000266643.6
membrane associated ring-CH-type finger 9
chr2_-_219543793 0.16 ENST00000243776.11
chondroitin polymerizing factor
chr2_+_112275588 0.16 ENST00000409871.6
ENST00000343936.4
zinc finger CCCH-type containing 6
chr4_+_127782270 0.16 ENST00000508549.5
ENST00000296464.9
heat shock protein family A (Hsp70) member 4 like
chr17_+_59155726 0.16 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr3_+_38453832 0.15 ENST00000352511.5
activin A receptor type 2B
chr18_+_57352541 0.14 ENST00000324000.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr7_+_90403386 0.14 ENST00000287916.8
ENST00000394604.5
ENST00000496677.6
ENST00000394605.2
ENST00000480135.1
claudin 12
novel transcript
chr14_+_30559142 0.13 ENST00000550944.5
ENST00000438909.6
ENST00000206595.11
ENST00000553504.5
G2/M-phase specific E3 ubiquitin protein ligase
chr4_+_183905266 0.13 ENST00000308497.9
storkhead box 2
chr1_-_243850070 0.13 ENST00000366539.6
ENST00000672578.1
AKT serine/threonine kinase 3
chr3_-_112499457 0.13 ENST00000334529.10
B and T lymphocyte associated
chr7_+_4682252 0.13 ENST00000328914.5
forkhead box K1
chr6_+_127118657 0.12 ENST00000356698.9
R-spondin 3
chr16_-_23149378 0.12 ENST00000219689.12
ubiquitin specific peptidase 31
chr4_+_93828746 0.11 ENST00000306011.6
atonal bHLH transcription factor 1
chr20_-_32483438 0.11 ENST00000359676.9
nucleolar protein 4 like
chr6_+_143608170 0.11 ENST00000427704.6
ENST00000305766.10
phosphatase and actin regulator 2
chr10_-_117375407 0.11 ENST00000334464.7
PDZ domain containing 8
chr2_+_167868948 0.11 ENST00000392690.3
beta-1,3-galactosyltransferase 1
chr4_+_165873231 0.10 ENST00000061240.7
tolloid like 1
chr19_-_14206168 0.10 ENST00000361434.7
ENST00000340736.10
adhesion G protein-coupled receptor L1
chr7_+_72879349 0.10 ENST00000395270.5
POM121 transmembrane nucleoporin
chr5_+_79612410 0.10 ENST00000423041.6
ENST00000504233.5
ENST00000453514.6
ENST00000428308.6
terminal nucleotidyltransferase 2
chr16_+_58515474 0.10 ENST00000310682.6
ENST00000394266.8
SET domain containing 6, protein lysine methyltransferase
chr2_+_231037500 0.09 ENST00000373640.5
chromosome 2 open reading frame 72
chr2_+_28392802 0.08 ENST00000379619.5
ENST00000264716.9
FOS like 2, AP-1 transcription factor subunit
chr16_-_46973634 0.08 ENST00000317089.10
DnaJ heat shock protein family (Hsp40) member A2
chr17_+_29593118 0.08 ENST00000394859.8
ankyrin repeat domain 13B
chr12_-_57006476 0.08 ENST00000300101.3
zinc finger and BTB domain containing 39
chr3_+_184315131 0.07 ENST00000427845.5
ENST00000342981.8
eukaryotic translation initiation factor 4 gamma 1
chr16_-_48610150 0.07 ENST00000262384.4
NEDD4 binding protein 1
chr9_-_92670124 0.07 ENST00000287996.8
inositol-pentakisphosphate 2-kinase
chr7_+_36389852 0.07 ENST00000265748.7
anillin actin binding protein
chr1_-_207051202 0.06 ENST00000315927.9
YOD1 deubiquitinase
chr15_+_69414304 0.06 ENST00000352331.8
ENST00000679126.1
ENST00000647715.1
ENST00000559279.6
kinesin family member 23
chr1_-_119648165 0.06 ENST00000421812.3
zinc finger protein 697
chr1_+_180230257 0.06 ENST00000263726.4
LIM homeobox 4
chr10_+_110871903 0.06 ENST00000280154.12
programmed cell death 4
chr1_+_26826682 0.06 ENST00000374142.9
zinc finger DHHC-type palmitoyltransferase 18
chr6_+_47477731 0.06 ENST00000359314.5
CD2 associated protein
chr20_-_53593829 0.06 ENST00000371471.7
zinc finger protein 217
chr3_+_189171948 0.06 ENST00000345063.8
tumor protein p63 regulated 1
chr3_+_196867856 0.06 ENST00000445299.6
ENST00000323460.10
ENST00000419026.5
SUMO specific peptidase 5
chr1_+_184386978 0.06 ENST00000235307.7
chromosome 1 open reading frame 21
chr18_+_32091849 0.05 ENST00000261593.8
ENST00000578914.1
ring finger protein 138
chr11_-_73142032 0.05 ENST00000311172.11
ENST00000409314.5
FCH and double SH3 domains 2
chr15_-_52569197 0.05 ENST00000563277.5
ENST00000566423.5
cAMP regulated phosphoprotein 19
chr19_-_17688326 0.05 ENST00000552293.5
ENST00000551649.5
ENST00000519716.7
ENST00000550896.1
unc-13 homolog A
chr17_-_5584448 0.05 ENST00000269280.8
ENST00000571451.6
ENST00000572272.6
ENST00000613500.4
ENST00000619223.4
ENST00000617618.4
ENST00000345221.7
ENST00000262467.10
NLR family pyrin domain containing 1
chr14_-_105021043 0.05 ENST00000392590.3
ENST00000336219.4
cell division cycle associated 4
chr7_+_141074038 0.05 ENST00000565468.6
ENST00000610315.1
transmembrane protein 178B
chr18_-_48950960 0.04 ENST00000262158.8
SMAD family member 7
chr2_+_61017562 0.04 ENST00000401576.1
ENST00000295030.6
ENST00000414712.2
peroxisomal biogenesis factor 13
chr3_+_122184233 0.04 ENST00000638421.1
ENST00000498619.4
calcium sensing receptor
chr11_+_9384621 0.04 ENST00000379719.8
ENST00000527431.1
ENST00000630083.1
importin 7
chr16_+_30699155 0.04 ENST00000262518.9
Snf2 related CREBBP activator protein
chrX_+_49922605 0.04 ENST00000376088.7
chloride voltage-gated channel 5
chr13_-_46387447 0.04 ENST00000676051.1
ENST00000378787.7
ENST00000378781.7
ENST00000378797.6
rubicon like autophagy enhancer
chr12_-_107761113 0.03 ENST00000228437.10
PR/SET domain 4
chr3_+_150408314 0.03 ENST00000361875.7
TSC22 domain family member 2
chr11_+_67391975 0.03 ENST00000307980.7
RAD9 checkpoint clamp component A
chr6_+_43076262 0.03 ENST00000476760.1
ENST00000230419.9
ENST00000471863.5
ENST00000345201.6
ENST00000349241.6
ENST00000352931.6
protein tyrosine kinase 7 (inactive)
chr2_+_197515565 0.03 ENST00000233892.8
ENST00000409916.5
MOB family member 4, phocein
chr11_+_117144277 0.03 ENST00000419197.6
ENST00000527958.6
ENST00000304808.10
ENST00000529887.6
ENST00000530272.1
platelet activating factor acetylhydrolase 1b catalytic subunit 2
chr15_+_49423233 0.03 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr11_-_61161414 0.03 ENST00000301765.10
VPS37C subunit of ESCRT-I
chr9_+_4679555 0.03 ENST00000381858.5
ENST00000381854.4
cell division cycle 37 like 1
chr10_+_86756580 0.03 ENST00000372037.8
bone morphogenetic protein receptor type 1A
chr3_+_42160160 0.02 ENST00000341421.7
ENST00000396175.5
trafficking kinesin protein 1
chr22_+_39502237 0.02 ENST00000325301.7
mitochondrial elongation factor 1
chr4_+_71339014 0.02 ENST00000340595.4
solute carrier family 4 member 4
chr1_+_109548567 0.02 ENST00000369851.7
G protein subunit alpha i3
chr22_+_45163910 0.02 ENST00000347635.9
ENST00000407019.6
ENST00000424634.5
ENST00000417702.5
ENST00000430547.5
nucleoporin 50
chr16_+_50548387 0.02 ENST00000268459.6
NKD inhibitor of WNT signaling pathway 1
chr1_+_15526813 0.02 ENST00000375838.5
ENST00000616884.4
ENST00000375849.5
ENST00000375847.8
DnaJ heat shock protein family (Hsp40) member C16
chr10_+_102918276 0.02 ENST00000369878.9
ENST00000369875.3
cyclin and CBS domain divalent metal cation transport mediator 2
chrX_+_129540236 0.02 ENST00000371113.9
ENST00000357121.5
OCRL inositol polyphosphate-5-phosphatase
chr19_+_49119531 0.02 ENST00000334186.9
PTPRF interacting protein alpha 3
chr16_+_67893244 0.02 ENST00000291041.6
ENST00000570631.5
protein serine kinase H1
chr11_-_65900413 0.02 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr6_+_41072939 0.02 ENST00000341376.11
ENST00000353205.5
nuclear transcription factor Y subunit alpha
chr5_-_39074377 0.01 ENST00000514735.1
ENST00000357387.8
ENST00000296782.9
RPTOR independent companion of MTOR complex 2
chr12_-_14803462 0.01 ENST00000261167.7
ENST00000535328.1
WW domain binding protein 11
chr17_-_29294141 0.01 ENST00000225388.9
nuclear FMR1 interacting protein 2
chr11_-_119381629 0.01 ENST00000260187.7
ENST00000455332.6
ubiquitin specific peptidase 2
chrX_-_84188148 0.01 ENST00000262752.5
ribosomal protein S6 kinase A6
chr3_-_120349294 0.01 ENST00000295628.4
leucine rich repeat containing 58
chr7_-_99438647 0.01 ENST00000430029.1
ENST00000419981.1
ENST00000292478.9
pentatricopeptide repeat domain 1
chr16_+_67846917 0.01 ENST00000219169.9
ENST00000567105.5
nuclear transport factor 2
chr5_+_73498408 0.01 ENST00000335895.12
ENST00000678135.1
ENST00000380591.7
ENST00000677654.1
ENST00000507081.6
basic transcription factor 3
chr7_-_99408548 0.01 ENST00000626285.1
ENST00000350498.8
PDGFA associated protein 1
chr16_-_88941198 0.01 ENST00000327483.9
ENST00000564416.1
CBFA2/RUNX1 partner transcriptional co-repressor 3
chr11_+_125626229 0.01 ENST00000532449.6
ENST00000534070.5
checkpoint kinase 1
chr2_-_219060914 0.00 ENST00000295731.7
Indian hedgehog signaling molecule
chr3_+_52455589 0.00 ENST00000345716.9
ENST00000488380.5
ENST00000420808.2
nischarin
chr11_-_126268810 0.00 ENST00000332118.11
SRP receptor subunit alpha
chr1_+_203795614 0.00 ENST00000367210.3
ENST00000432282.5
ENST00000453771.5
ENST00000367214.5
ENST00000639812.1
ENST00000367212.7
ENST00000332127.8
ENST00000550078.2
zinc finger CCCH-type containing 11A
zinc finger BED-type containing 6

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCAGCG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.4 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.3 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.7 GO:0060066 regulation of axon diameter(GO:0031133) oviduct development(GO:0060066)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.7 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.6 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.4 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 1.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.4 GO:0070166 desmosome organization(GO:0002934) enamel mineralization(GO:0070166)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:1904172 regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:1990168 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.0 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.5 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.6 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.5 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0048495 laminin-1 binding(GO:0043237) Roundabout binding(GO:0048495)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions