Project

avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

Navigation
Downloads

Results for AIRE

Z-value: 0.32

Motif logo

Transcription factors associated with AIRE

Gene Symbol Gene ID Gene Info
ENSG00000160224.17 autoimmune regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
AIREhg38_v1_chr21_+_44285869_442858840.019.8e-01Click!

Activity profile of AIRE motif

Sorted Z-values of AIRE motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_75480800 0.56 ENST00000456650.7
GLI pathogenesis related 1
chr12_+_75481204 0.53 ENST00000550491.1
GLI pathogenesis related 1
chrM_+_12329 0.38 ENST00000361567.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr12_+_75480745 0.37 ENST00000266659.8
GLI pathogenesis related 1
chr14_+_75632610 0.25 ENST00000555027.1
FLVCR heme transporter 2
chr2_-_224947030 0.23 ENST00000409592.7
dedicator of cytokinesis 10
chr2_-_189179754 0.23 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr2_-_165204042 0.19 ENST00000283254.12
ENST00000453007.1
sodium voltage-gated channel alpha subunit 3
chr17_-_40565459 0.19 ENST00000578085.1
ENST00000246657.2
C-C motif chemokine receptor 7
chr8_+_103372388 0.19 ENST00000520337.1
collagen triple helix repeat containing 1
chr2_-_237414127 0.19 ENST00000472056.5
collagen type VI alpha 3 chain
chr4_-_185775271 0.18 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr5_+_141392616 0.16 ENST00000398604.3
protocadherin gamma subfamily A, 8
chr12_+_50924005 0.15 ENST00000550502.1
methyltransferase like 7A
chrX_-_101052087 0.15 ENST00000372936.4
ENST00000545398.5
tRNA methyltransferase 2 homolog B
chrX_-_101052054 0.15 ENST00000372939.5
ENST00000372935.5
tRNA methyltransferase 2 homolog B
chr12_+_12049855 0.13 ENST00000586576.5
ENST00000464885.6
BCL2 like 14
chr9_-_110999458 0.13 ENST00000374430.6
lysophosphatidic acid receptor 1
chr9_+_87497222 0.13 ENST00000358077.9
death associated protein kinase 1
chr12_+_12070932 0.13 ENST00000308721.9
BCL2 like 14
chr12_+_12049840 0.13 ENST00000589718.5
BCL2 like 14
chr10_-_100081854 0.13 ENST00000370418.8
carboxypeptidase N subunit 1
chr1_+_209938207 0.13 ENST00000472886.5
synaptotagmin 14
chr12_+_54854505 0.13 ENST00000308796.11
ENST00000619042.1
mucin like 1
chr1_+_209938169 0.12 ENST00000367019.5
ENST00000537238.5
ENST00000637265.1
synaptotagmin 14
chr12_+_12071396 0.12 ENST00000396367.5
ENST00000266434.8
BCL2 like 14
chr20_+_8789517 0.11 ENST00000437439.2
phospholipase C beta 1
chr6_-_31546552 0.11 ENST00000303892.10
ENST00000376151.4
ATPase H+ transporting V1 subunit G2
chr12_+_20695553 0.11 ENST00000545102.1
solute carrier organic anion transporter family member 1C1
chr16_-_47459130 0.11 ENST00000565940.6
integrin alpha FG-GAP repeat containing 1
chr2_-_43676406 0.10 ENST00000475092.4
C1GALT1 specific chaperone 1 like
chr19_-_52048561 0.10 ENST00000594154.5
ENST00000598745.5
ENST00000597273.1
zinc finger protein 432
chr7_+_149872955 0.10 ENST00000421974.7
ENST00000456496.7
ATPase H+ transporting V0 subunit e2
chr19_-_52048803 0.09 ENST00000221315.10
zinc finger protein 432
chr20_+_13008919 0.09 ENST00000399002.7
ENST00000434210.5
serine palmitoyltransferase long chain base subunit 3
chr1_+_174874434 0.09 ENST00000478442.5
ENST00000465412.5
RAB GTPase activating protein 1 like
chr3_-_121749704 0.09 ENST00000393667.7
ENST00000340645.9
ENST00000614479.4
golgin B1
chr12_-_11134644 0.09 ENST00000539585.1
taste 2 receptor member 30
chrM_+_5824 0.09 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr16_-_89418292 0.09 ENST00000683497.1
ENST00000642443.1
ENST00000644784.1
ENST00000647238.1
novel protein
ankyrin repeat domain 11
chr1_+_78649818 0.09 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr1_+_15153698 0.09 ENST00000400796.7
ENST00000376008.3
ENST00000434578.6
transmembrane protein 51
chr15_+_21651844 0.08 ENST00000623441.1
olfactory receptor family 4 subfamily N member 4C
chr9_-_21482313 0.08 ENST00000448696.4
interferon epsilon
chr3_-_126558926 0.08 ENST00000318225.3
chromosome 3 open reading frame 22
chr15_+_22094522 0.08 ENST00000328795.5
olfactory receptor family 4 subfamily N member 4
chrM_+_4467 0.08 ENST00000361453.3
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
chr1_+_241652275 0.08 ENST00000366552.6
ENST00000437684.7
WD repeat domain 64
chr6_+_36871841 0.08 ENST00000359359.6
chromosome 6 open reading frame 89
chr2_+_37950432 0.07 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
regulator of microtubule dynamics 2
chr16_+_50025217 0.07 ENST00000427478.7
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr10_+_89283685 0.07 ENST00000638108.1
interferon induced protein with tetratricopeptide repeats 2
chrX_-_140784366 0.06 ENST00000674533.1
cerebellar degeneration related protein 1
chr19_-_51028015 0.06 ENST00000319720.11
kallikrein related peptidase 11
chr9_-_92536031 0.06 ENST00000344604.9
ENST00000375540.5
extracellular matrix protein 2
chr6_-_149484965 0.06 ENST00000409806.8
zinc finger CCCH-type containing 12D
chr19_+_15615211 0.06 ENST00000617645.4
ENST00000612078.5
cytochrome P450 family 4 subfamily F member 8
chr11_-_71821548 0.06 ENST00000525199.1
zinc finger protein 705E
chr13_-_46182136 0.06 ENST00000323076.7
lymphocyte cytosolic protein 1
chr20_-_35147285 0.06 ENST00000374491.3
ENST00000374492.8
ER degradation enhancing alpha-mannosidase like protein 2
chr21_+_38272250 0.06 ENST00000398932.5
potassium inwardly rectifying channel subfamily J member 15
chr10_+_94089034 0.06 ENST00000676102.1
ENST00000371385.8
phospholipase C epsilon 1
chr2_+_165294031 0.06 ENST00000283256.10
sodium voltage-gated channel alpha subunit 2
chr13_-_48413105 0.06 ENST00000620633.5
lysophosphatidic acid receptor 6
chr21_+_38272410 0.06 ENST00000398934.5
ENST00000398930.5
potassium inwardly rectifying channel subfamily J member 15
chr3_+_136819069 0.05 ENST00000393079.3
ENST00000446465.3
solute carrier family 35 member G2
chrM_+_7586 0.05 ENST00000361739.1
mitochondrially encoded cytochrome c oxidase II
chr16_+_14708944 0.05 ENST00000526520.5
ENST00000531598.6
nuclear pore complex interacting protein family member A3
chr19_+_13151975 0.05 ENST00000588173.1
immediate early response 2
chr17_+_63484840 0.05 ENST00000290863.10
ENST00000413513.7
angiotensin I converting enzyme
chr14_-_55191534 0.05 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chr1_-_35031905 0.05 ENST00000317538.9
ENST00000357182.9
zinc finger MYM-type containing 6
chr11_+_7088991 0.05 ENST00000306904.7
RBMX like 2
chr19_+_44914702 0.05 ENST00000592885.5
ENST00000589781.1
apolipoprotein C1
chr11_-_117098415 0.05 ENST00000445177.6
ENST00000375300.6
ENST00000446921.6
SIK family kinase 3
chr19_-_51027954 0.05 ENST00000391804.7
kallikrein related peptidase 11
chr16_+_32066065 0.05 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr14_+_22112280 0.05 ENST00000390454.2
T cell receptor alpha variable 25
chr19_+_55769118 0.04 ENST00000341750.5
ret finger protein like 4A like 1
chr17_-_43942472 0.04 ENST00000225992.8
pancreatic polypeptide
chr14_-_24442662 0.04 ENST00000554698.5
short chain dehydrogenase/reductase family 39U member 1
chr2_-_222656067 0.04 ENST00000281828.8
phenylalanyl-tRNA synthetase subunit beta
chr1_-_21783134 0.04 ENST00000308271.14
ubiquitin specific peptidase 48
chr6_-_26043704 0.04 ENST00000615966.2
H2B clustered histone 3
chr19_+_44914588 0.04 ENST00000592535.6
apolipoprotein C1
chr7_-_15561986 0.04 ENST00000342526.8
alkylglycerol monooxygenase
chr19_-_10380558 0.04 ENST00000524462.5
ENST00000525621.6
ENST00000531836.5
tyrosine kinase 2
chr17_+_3420568 0.04 ENST00000574571.4
olfactory receptor family 3 subfamily A member 3
chr16_-_28491996 0.04 ENST00000568497.6
ENST00000357857.14
ENST00000395653.9
ENST00000635973.1
ENST00000568443.2
ENST00000568558.6
ENST00000565688.5
ENST00000637100.1
ENST00000359984.12
ENST00000636147.2
ENST00000567963.6
CLN3 lysosomal/endosomal transmembrane protein, battenin
chr19_-_58573555 0.03 ENST00000599369.5
myeloid zinc finger 1
chr1_+_47137435 0.03 ENST00000371891.8
ENST00000371890.7
ENST00000619754.4
ENST00000294337.7
ENST00000620131.1
cytochrome P450 family 4 subfamily A member 22
chr19_+_44914833 0.03 ENST00000589078.1
ENST00000586638.5
apolipoprotein C1
chr2_+_113437691 0.03 ENST00000259199.9
ENST00000416503.6
ENST00000433343.6
COBW domain containing 2
chr17_-_3398410 0.03 ENST00000322608.2
olfactory receptor family 1 subfamily E member 1
chr11_-_85665077 0.03 ENST00000527447.2
CREB/ATF bZIP transcription factor
chr12_-_6470667 0.03 ENST00000361716.8
ENST00000396308.4
vesicle associated membrane protein 1
chr2_-_37671633 0.03 ENST00000295324.4
CDC42 effector protein 3
chr4_-_65670478 0.03 ENST00000613740.5
ENST00000622150.4
ENST00000511294.1
EPH receptor A5
chr9_+_105662457 0.03 ENST00000334077.6
TAL bHLH transcription factor 2
chr3_+_39383337 0.03 ENST00000650617.1
ENST00000431510.1
ENST00000645630.1
solute carrier family 25 member 38
chr3_-_19934189 0.03 ENST00000295824.14
EF-hand domain family member B
chr17_+_79034185 0.03 ENST00000581774.5
C1q and TNF related 1
chr3_+_189789672 0.03 ENST00000434928.5
tumor protein p63
chr9_-_19049319 0.03 ENST00000542071.2
ENST00000649457.1
stabilizer of axonemal microtubules 1
chr2_-_240820945 0.03 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
kinesin family member 1A
chr4_-_174829212 0.03 ENST00000340217.5
ENST00000274093.8
glycine receptor alpha 3
chr7_-_99735093 0.03 ENST00000611620.4
ENST00000620220.6
ENST00000336374.4
CYP3A7-CYP3A51P readthrough
cytochrome P450 family 3 subfamily A member 7
chr1_-_85708382 0.03 ENST00000370574.4
ENST00000431532.6
zinc finger HIT-type containing 6
chr9_-_4666347 0.03 ENST00000381890.9
ENST00000682582.1
spermatogenesis associated 6 like
chr3_-_36739791 0.03 ENST00000416516.2
doublecortin like kinase 3
chr5_+_141245384 0.02 ENST00000623671.1
ENST00000231173.6
protocadherin beta 15
chrM_-_14669 0.02 ENST00000361681.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6
chr12_-_75209701 0.02 ENST00000350228.6
ENST00000298972.5
potassium voltage-gated channel subfamily C member 2
chr2_-_27370009 0.02 ENST00000451130.6
eukaryotic translation initiation factor 2B subunit delta
chr2_-_135876382 0.02 ENST00000264156.3
minichromosome maintenance complex component 6
chr5_-_78549151 0.02 ENST00000515007.6
LHFPL tetraspan subfamily member 2
chr4_-_65670339 0.02 ENST00000273854.7
EPH receptor A5
chrX_-_49080066 0.02 ENST00000634944.1
ENST00000423215.3
ENST00000465382.6
WD repeat domain 45
chr19_-_43883964 0.02 ENST00000587539.2
zinc finger protein 404
chr8_+_103298433 0.02 ENST00000522566.5
frizzled class receptor 6
chr19_-_23687163 0.02 ENST00000601010.5
ENST00000601935.5
ENST00000600313.5
ENST00000596211.5
ENST00000359788.9
ENST00000599168.1
zinc finger protein 675
chr19_-_3600581 0.02 ENST00000589966.1
thromboxane A2 receptor
chr21_+_38272291 0.02 ENST00000438657.5
potassium inwardly rectifying channel subfamily J member 15
chr14_-_24442765 0.02 ENST00000555365.5
ENST00000399395.8
ENST00000553930.5
short chain dehydrogenase/reductase family 39U member 1
chr8_-_16186270 0.02 ENST00000445506.6
macrophage scavenger receptor 1
chr11_-_5324297 0.02 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr3_-_88149815 0.02 ENST00000467332.1
ENST00000462901.5
CGG triplet repeat binding protein 1
chr11_+_6926417 0.02 ENST00000610573.4
ENST00000278319.10
zinc finger protein 215
chr1_-_51878711 0.02 ENST00000352171.12
nardilysin convertase
chr4_-_146945841 0.02 ENST00000325106.9
tetratricopeptide repeat domain 29
chr17_+_7306975 0.02 ENST00000336452.11
eukaryotic translation initiation factor 5A
chr13_+_52455429 0.02 ENST00000468284.1
ENST00000378034.7
ENST00000378037.9
ENST00000258607.10
cytoskeleton associated protein 2
chr12_-_6470643 0.02 ENST00000535180.5
ENST00000400911.7
vesicle associated membrane protein 1
chr1_-_51878799 0.02 ENST00000354831.11
ENST00000544028.5
nardilysin convertase
chr9_-_29739 0.02 ENST00000442898.5
WASH complex subunit 1
chr19_+_55857437 0.02 ENST00000587891.5
NLR family pyrin domain containing 4
chr4_-_146945873 0.02 ENST00000502319.1
ENST00000504425.5
tetratricopeptide repeat domain 29
chr11_+_35189964 0.02 ENST00000524922.1
CD44 molecule (Indian blood group)
chr8_-_7452365 0.02 ENST00000458665.5
ENST00000528168.3
sperm associated antigen 11B
chr4_-_146945807 0.02 ENST00000513335.5
tetratricopeptide repeat domain 29
chr8_+_53851786 0.02 ENST00000297313.8
ENST00000344277.10
regulator of G protein signaling 20
chr2_-_165953750 0.02 ENST00000243344.8
ENST00000679799.1
ENST00000679840.1
ENST00000681606.1
ENST00000680448.1
tetratricopeptide repeat domain 21B
chr1_+_207496147 0.02 ENST00000400960.7
ENST00000367049.9
complement C3b/C4b receptor 1 (Knops blood group)
chr4_-_103099811 0.01 ENST00000504285.5
ENST00000296424.9
3-hydroxybutyrate dehydrogenase 2
chr17_+_56153458 0.01 ENST00000318698.6
ENST00000682825.1
ENST00000566473.6
ankyrin repeat and fibronectin type III domain containing 1
chr7_-_88306880 0.01 ENST00000414498.1
ENST00000301959.9
ENST00000380079.9
STEAP4 metalloreductase
chr3_+_88149947 0.01 ENST00000318887.8
ENST00000486971.1
chromosome 3 open reading frame 38
chr19_+_16496383 0.01 ENST00000594035.5
ENST00000221671.8
ENST00000599550.1
ENST00000594813.1
chromosome 19 open reading frame 44
chr17_+_43780425 0.01 ENST00000449302.8
CFAP97 domain containing 1
chr12_-_11310420 0.01 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
proline rich protein BstNI subfamily 4
chr12_+_4649097 0.01 ENST00000648836.1
ENST00000266544.10
novel protein
NADH:ubiquinone oxidoreductase subunit A9
chr14_+_45135917 0.01 ENST00000267430.10
ENST00000556036.5
ENST00000542564.6
FA complementation group M
chr14_+_22105305 0.01 ENST00000390453.1
T cell receptor alpha variable 24
chr6_+_28267044 0.01 ENST00000316606.10
zinc finger and SCAN domain containing 26
chr6_+_46129930 0.01 ENST00000321037.5
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr12_-_62192762 0.01 ENST00000416284.8
TAFA chemokine like family member 2
chr1_+_100345018 0.01 ENST00000635056.2
ENST00000647005.1
cell division cycle 14A
chr1_+_111473972 0.01 ENST00000369718.4
chromosome 1 open reading frame 162
chr19_-_16496156 0.00 ENST00000269881.8
calreticulin 3
chr1_-_16431371 0.00 ENST00000612240.1
spermatogenesis associated 21
chr22_+_24806265 0.00 ENST00000400359.4
small G protein signaling modulator 1
chr4_-_16084002 0.00 ENST00000447510.7
prominin 1
chr16_+_3204247 0.00 ENST00000304646.2
olfactory receptor family 1 subfamily F member 1
chr1_+_162497805 0.00 ENST00000538489.5
ENST00000489294.2
U2AF homology motif kinase 1
chr12_-_11269696 0.00 ENST00000381842.7
proline rich protein BstNI subfamily 3
chr1_-_154627576 0.00 ENST00000648311.1
adenosine deaminase RNA specific
chr22_+_41621977 0.00 ENST00000405506.2
X-ray repair cross complementing 6
chr7_+_20647343 0.00 ENST00000443026.6
ENST00000406935.5
ATP binding cassette subfamily B member 5
chrX_-_103686687 0.00 ENST00000441076.7
ENST00000422355.5
ENST00000442614.5
ENST00000451301.5
mortality factor 4 like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of AIRE

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.0 0.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.0 GO:0036233 glycine import(GO:0036233)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:0008241 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)