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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for ATF5

Z-value: 0.99

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Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ENSG00000169136.12 activating transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF5hg38_v1_chr19_+_49928702_499287690.472.4e-01Click!

Activity profile of ATF5 motif

Sorted Z-values of ATF5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_188974364 1.09 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr6_+_71886900 0.93 ENST00000517960.5
ENST00000518273.5
ENST00000522291.5
ENST00000521978.5
ENST00000520567.5
ENST00000264839.11
regulating synaptic membrane exocytosis 1
chr6_+_71886703 0.70 ENST00000491071.6
regulating synaptic membrane exocytosis 1
chr5_-_20575850 0.67 ENST00000507958.5
cadherin 18
chr6_+_101181254 0.63 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr2_-_187554351 0.62 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr1_+_215082731 0.50 ENST00000444842.7
potassium two pore domain channel subfamily K member 2
chr8_-_13276491 0.46 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr10_+_102419189 0.43 ENST00000432590.5
F-box and leucine rich repeat protein 15
chr5_+_83471925 0.41 ENST00000502527.2
versican
chr2_-_213151590 0.39 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr8_+_78516329 0.39 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr1_-_46132650 0.39 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr5_+_137867868 0.38 ENST00000515645.1
myotilin
chr12_+_32502114 0.37 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FYVE, RhoGEF and PH domain containing 4
chr5_+_83471764 0.36 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
versican
chr3_-_187736493 0.35 ENST00000232014.8
BCL6 transcription repressor
chr14_+_23377136 0.34 ENST00000382809.2
CKLF like MARVEL transmembrane domain containing 5
chr5_+_83471668 0.34 ENST00000342785.8
ENST00000343200.9
versican
chr5_+_83471736 0.33 ENST00000265077.8
versican
chrX_-_136780925 0.32 ENST00000250617.7
Rac/Cdc42 guanine nucleotide exchange factor 6
chr21_-_43058941 0.31 ENST00000451248.5
ENST00000458223.5
cystathionine beta-synthase
chr14_+_23376765 0.30 ENST00000649278.1
CKLF like MARVEL transmembrane domain containing 5
chr17_-_7043906 0.30 ENST00000308009.5
ENST00000447225.1
solute carrier family 16 member 11
chr14_-_65102339 0.30 ENST00000555419.5
MYC associated factor X
chr17_-_7044091 0.30 ENST00000574600.3
ENST00000662352.3
ENST00000673828.2
solute carrier family 16 member 11
chr1_-_16978276 0.30 ENST00000375534.7
microfibril associated protein 2
chr6_+_113857333 0.29 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr14_-_65102383 0.29 ENST00000341653.6
MYC associated factor X
chr20_+_44582549 0.28 ENST00000372886.6
cAMP-dependent protein kinase inhibitor gamma
chr2_-_187554473 0.26 ENST00000453013.5
ENST00000417013.5
tissue factor pathway inhibitor
chr5_+_137867852 0.26 ENST00000421631.6
ENST00000239926.9
myotilin
chr14_+_23377001 0.25 ENST00000342473.8
ENST00000397227.7
ENST00000339180.9
ENST00000555731.5
CKLF like MARVEL transmembrane domain containing 5
chr2_-_86790900 0.25 ENST00000283635.8
CD8a molecule
chr19_+_48465837 0.24 ENST00000595676.1
novel protein
chr2_+_27051637 0.24 ENST00000451003.5
ENST00000360131.5
ENST00000323064.12
ATP/GTP binding protein like 5
chr8_+_35235467 0.23 ENST00000404895.7
unc-5 netrin receptor D
chr14_+_23376786 0.23 ENST00000359320.7
CKLF like MARVEL transmembrane domain containing 5
chr4_+_70242583 0.23 ENST00000304954.3
casein kappa
chr1_-_145095528 0.22 ENST00000612199.4
ENST00000641863.1
SLIT-ROBO Rho GTPase activating protein 2B
chr15_+_63189554 0.22 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr9_+_2622053 0.22 ENST00000681306.1
ENST00000681618.1
very low density lipoprotein receptor
chr5_+_111223905 0.22 ENST00000512453.5
calcium/calmodulin dependent protein kinase IV
chr1_+_151766655 0.21 ENST00000400999.7
ornithine decarboxylase antizyme 3
chr8_+_38820332 0.20 ENST00000518809.5
ENST00000520611.1
transforming acidic coiled-coil containing protein 1
chr6_-_31546552 0.20 ENST00000303892.10
ENST00000376151.4
ATPase H+ transporting V1 subunit G2
chr4_+_158521937 0.20 ENST00000343542.9
ENST00000470033.2
relaxin family peptide receptor 1
chr9_+_2621766 0.20 ENST00000382100.8
very low density lipoprotein receptor
chr20_+_56412249 0.19 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chr5_+_126631680 0.18 ENST00000357147.4
testis expressed 43
chr1_+_121184964 0.18 ENST00000367123.8
SLIT-ROBO Rho GTPase activating protein 2C
chr12_-_54258275 0.18 ENST00000552562.1
chromobox 5
chr12_-_114683590 0.18 ENST00000257566.7
T-box transcription factor 3
chr10_+_110005804 0.17 ENST00000360162.7
adducin 3
chr2_-_40512361 0.17 ENST00000403092.5
solute carrier family 8 member A1
chr12_-_114684151 0.17 ENST00000349155.7
T-box transcription factor 3
chr19_-_38840178 0.17 ENST00000594769.5
ENST00000602021.1
novel protein
chr20_+_56412112 0.16 ENST00000360314.7
Cas scaffold protein family member 4
chrX_-_19965142 0.16 ENST00000340625.3
BCLAF1 and THRAP3 family member 3
chr16_-_72093557 0.16 ENST00000562153.5
thioredoxin like 4B
chr21_-_26843063 0.16 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr17_+_35587239 0.16 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr21_-_26843012 0.15 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr22_-_35840577 0.15 ENST00000405409.6
RNA binding fox-1 homolog 2
chr12_+_32107151 0.15 ENST00000548411.5
BICD cargo adaptor 1
chr1_+_206406377 0.15 ENST00000605476.5
SLIT-ROBO Rho GTPase activating protein 2
chr17_+_35587478 0.14 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr14_-_65102468 0.14 ENST00000555932.5
ENST00000284165.10
ENST00000358402.8
ENST00000246163.2
ENST00000358664.9
ENST00000556979.5
ENST00000555667.5
ENST00000557746.5
ENST00000556443.5
ENST00000618858.4
ENST00000557277.5
ENST00000556892.5
MYC associated factor X
chr7_+_43764191 0.14 ENST00000424330.1
biliverdin reductase A
chr12_+_9971402 0.14 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
C-type lectin domain family 12 member A
chr17_+_35147807 0.13 ENST00000394570.7
ENST00000268876.9
unc-45 myosin chaperone B
chr1_+_61404076 0.13 ENST00000357977.5
nuclear factor I A
chr20_+_56412393 0.13 ENST00000679529.1
Cas scaffold protein family member 4
chr14_+_79279403 0.12 ENST00000281127.11
neurexin 3
chr1_-_182671902 0.12 ENST00000483095.6
regulator of G protein signaling 8
chr12_-_12338674 0.12 ENST00000545735.1
MANSC domain containing 1
chr8_+_106726115 0.12 ENST00000521592.5
oxidation resistance 1
chrX_+_154144242 0.12 ENST00000369951.9
opsin 1, long wave sensitive
chr1_-_182671853 0.12 ENST00000367556.5
regulator of G protein signaling 8
chr17_-_48944772 0.12 ENST00000290330.7
ENST00000502492.6
SNF8 subunit of ESCRT-II
chrX_+_154182596 0.11 ENST00000595290.6
opsin 1, medium wave sensitive
chr13_+_27792479 0.11 ENST00000302945.3
GS homeobox 1
chr11_-_6440980 0.11 ENST00000265983.8
ENST00000615166.1
hemopexin
chr5_+_139293939 0.11 ENST00000508689.1
ENST00000514528.5
matrin 3
chr5_+_51383394 0.11 ENST00000230658.12
ISL LIM homeobox 1
chr11_+_118606428 0.11 ENST00000361417.6
pleckstrin homology like domain family B member 1
chr14_+_79279906 0.10 ENST00000428277.6
neurexin 3
chr3_-_99850976 0.10 ENST00000487087.5
filamin A interacting protein 1 like
chr22_-_35840218 0.10 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr9_+_79573162 0.10 ENST00000425506.5
TLE family member 4, transcriptional corepressor
chr11_-_64166102 0.10 ENST00000255681.7
ENST00000675777.1
mono-ADP ribosylhydrolase 1
chr1_+_206203541 0.09 ENST00000573034.8
SLIT-ROBO Rho GTPase activating protein 2
chr12_-_120446372 0.09 ENST00000546954.2
TP53 regulated inhibitor of apoptosis 1
chr17_-_75153826 0.09 ENST00000481647.5
ENST00000470924.5
Jupiter microtubule associated homolog 1
chr7_-_102592444 0.09 ENST00000514917.3
novel protein
chr2_-_196171565 0.09 ENST00000263955.9
serine/threonine kinase 17b
chr3_+_19947316 0.09 ENST00000422242.1
RAB5A, member RAS oncogene family
chr22_-_35961623 0.09 ENST00000408983.2
RNA binding fox-1 homolog 2
chrX_+_155071414 0.09 ENST00000340647.8
BRCA1/BRCA2-containing complex subunit 3
chr11_+_62728642 0.09 ENST00000532583.1
tetratricopeptide repeat domain 9C
chr16_-_30012294 0.08 ENST00000564979.5
ENST00000563378.5
double C2 domain alpha
chr1_+_177170916 0.08 ENST00000361539.5
BMP/retinoic acid inducible neural specific 2
chr6_+_31897775 0.08 ENST00000469372.5
ENST00000497706.5
complement C2
chr19_-_18255385 0.08 ENST00000355502.7
ENST00000643046.1
novel protein
novel protein
chr10_-_7410973 0.08 ENST00000684547.1
ENST00000673876.1
ENST00000397167.6
Scm like with four mbt domains 2
chr2_-_87021844 0.08 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr1_+_211259932 0.07 ENST00000367005.8
REST corepressor 3
chr19_-_55580829 0.07 ENST00000592239.1
ENST00000325421.7
zinc finger protein 579
chr7_+_128758947 0.07 ENST00000493278.1
calumenin
chr2_+_87748087 0.07 ENST00000359481.9
plasminogen like B2
chr3_+_190388120 0.07 ENST00000456423.2
ENST00000264734.3
claudin 16
chr13_-_36297838 0.07 ENST00000511166.1
CCDC169-SOHLH2 readthrough
chr14_+_79279681 0.07 ENST00000679122.1
neurexin 3
chr1_+_66534171 0.07 ENST00000682762.1
ENST00000424320.6
SH3GL interacting endocytic adaptor 1
chr4_+_133149307 0.07 ENST00000618019.1
protocadherin 10
chr1_+_66534082 0.07 ENST00000683257.1
ENST00000684083.1
ENST00000682938.1
ENST00000683581.1
ENST00000682293.1
SH3GL interacting endocytic adaptor 1
chrX_-_13817346 0.06 ENST00000356942.9
glycoprotein M6B
chr1_+_3690654 0.06 ENST00000378285.5
ENST00000378280.5
ENST00000378288.8
tumor protein p73
chr13_-_36370111 0.06 ENST00000650221.1
spartin
chr5_+_139293660 0.06 ENST00000512876.5
ENST00000513678.5
matrin 3
chr1_-_158330957 0.06 ENST00000451207.5
CD1b molecule
chr7_-_100464248 0.06 ENST00000332375.4
chromosome 7 open reading frame 61
chr3_-_182980531 0.06 ENST00000292782.9
ENST00000632685.1
defective in cullin neddylation 1 domain containing 1
chr12_-_24949026 0.06 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
branched chain amino acid transaminase 1
chr12_+_120446418 0.06 ENST00000551765.6
ENST00000229384.5
glutamyl-tRNA amidotransferase subunit C
chr7_-_116030735 0.06 ENST00000393485.5
transcription factor EC
chr7_-_42152396 0.06 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI family zinc finger 3
chr15_-_75579248 0.06 ENST00000306726.6
ENST00000618819.5
protein tyrosine phosphatase non-receptor type 9
chr1_+_66534107 0.06 ENST00000371037.9
ENST00000684651.1
SH3GL interacting endocytic adaptor 1
chrX_-_13817027 0.06 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr12_-_110502065 0.06 ENST00000447578.6
ENST00000546588.1
ENST00000360579.11
ENST00000549578.6
ENST00000549970.5
VPS29 retromer complex component
chr11_+_62728465 0.06 ENST00000316461.9
tetratricopeptide repeat domain 9C
chr1_-_206970457 0.06 ENST00000324852.9
ENST00000450945.3
ENST00000400962.8
Fc fragment of IgA and IgM receptor
chr1_+_66534014 0.06 ENST00000684664.1
ENST00000682416.1
ENST00000683499.1
SH3GL interacting endocytic adaptor 1
chr12_-_52573816 0.06 ENST00000549343.5
ENST00000305620.3
keratin 74
chrX_+_132023580 0.06 ENST00000496850.1
serine/threonine kinase 26
chr5_+_155013755 0.06 ENST00000435029.6
kinesin family member 4B
chrX_+_154219756 0.05 ENST00000369929.8
opsin 1, medium wave sensitive 2
chr19_-_54360949 0.05 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr13_-_36370171 0.05 ENST00000355182.8
spartin
chr10_+_101354083 0.05 ENST00000408038.6
ENST00000370187.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr12_+_56521798 0.05 ENST00000262031.10
RNA binding motif single stranded interacting protein 2
chr19_+_32405758 0.05 ENST00000392250.7
dpy-19 like C-mannosyltransferase 3
chr14_+_79280263 0.05 ENST00000555387.1
neurexin 3
chr5_-_39219555 0.05 ENST00000512982.4
ENST00000351578.12
ENST00000509072.5
ENST00000504542.1
ENST00000506557.5
FYN binding protein 1
chr1_+_42463221 0.05 ENST00000654683.1
ENST00000667205.1
ENST00000655164.1
ENST00000657597.1
ENST00000667947.1
ENST00000668663.1
ENST00000660083.1
ENST00000655845.1
ENST00000671281.1
ENST00000664805.1
ENST00000654604.1
ENST00000655447.1
ENST00000661864.1
ENST00000665176.1
ENST00000670982.1
ENST00000668036.1
coiled-coil domain containing 30
chr8_+_37695774 0.05 ENST00000331569.6
zinc finger protein 703
chr8_+_99013247 0.05 ENST00000441350.2
ENST00000357162.7
ENST00000358544.7
vacuolar protein sorting 13 homolog B
chr6_-_87702221 0.05 ENST00000257787.6
akirin 2
chr10_+_101354028 0.05 ENST00000393441.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr22_-_26479664 0.05 ENST00000402105.7
HPS4 biogenesis of lysosomal organelles complex 3 subunit 2
chr1_+_66533948 0.05 ENST00000684178.1
SH3GL interacting endocytic adaptor 1
chr7_+_133253064 0.05 ENST00000393161.6
ENST00000253861.5
exocyst complex component 4
chr14_+_49598910 0.05 ENST00000298288.11
leucine rich repeat protein 1
chr5_+_80319997 0.05 ENST00000296739.6
spermatogenic leucine zipper 1
chr19_-_10380558 0.05 ENST00000524462.5
ENST00000525621.6
ENST00000531836.5
tyrosine kinase 2
chr3_-_101513175 0.05 ENST00000394091.5
ENST00000394094.6
ENST00000394095.7
ENST00000348610.3
ENST00000314261.11
SUMO specific peptidase 7
chr4_-_174829212 0.04 ENST00000340217.5
ENST00000274093.8
glycine receptor alpha 3
chr6_-_32176051 0.04 ENST00000375107.8
1-acylglycerol-3-phosphate O-acyltransferase 1
chr2_-_190062721 0.04 ENST00000260950.5
myostatin
chr16_+_22092532 0.04 ENST00000567131.5
ENST00000389398.10
ENST00000568328.5
von Willebrand factor A domain containing 3A
chr11_-_40294089 0.04 ENST00000278198.2
leucine rich repeat containing 4C
chr4_+_83456045 0.04 ENST00000507349.5
ENST00000295491.9
ENST00000509970.5
ENST00000505719.1
mitochondrial ribosomal protein S18C
chr16_-_72093598 0.04 ENST00000268483.8
thioredoxin like 4B
chr8_+_20197369 0.04 ENST00000276390.7
ENST00000519667.1
ATPase H+ transporting V1 subunit B2
chr12_+_53380639 0.04 ENST00000426431.2
Sp1 transcription factor
chr2_-_208254232 0.04 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chr7_-_42152444 0.04 ENST00000479210.1
GLI family zinc finger 3
chr10_-_102419934 0.04 ENST00000406432.5
pleckstrin and Sec7 domain containing
chr19_-_45370384 0.04 ENST00000485403.6
ENST00000586856.1
ENST00000586131.6
ENST00000391945.10
ENST00000684407.1
ENST00000391944.8
ERCC excision repair 2, TFIIH core complex helicase subunit
chr22_+_37282464 0.04 ENST00000402997.5
ENST00000405206.3
ENST00000248901.11
cytohesin 4
chr3_+_19947074 0.04 ENST00000273047.9
RAB5A, member RAS oncogene family
chr6_-_160664270 0.04 ENST00000316300.10
lipoprotein(a)
chrX_-_155071064 0.03 ENST00000369484.8
ENST00000369476.8
C-X9-C motif containing 4
mature T cell proliferation 1
chr8_-_109680812 0.03 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
syntabulin
chr11_+_63681573 0.03 ENST00000354497.4
reticulon 3
chr14_+_49598761 0.03 ENST00000318317.8
leucine rich repeat protein 1
chr9_-_113303271 0.03 ENST00000297894.5
ENST00000489339.2
ring finger protein 183
chr11_+_63681483 0.03 ENST00000339997.8
ENST00000540798.5
ENST00000545432.5
ENST00000543552.5
ENST00000377819.10
ENST00000537981.5
reticulon 3
chr12_+_32106762 0.03 ENST00000551848.1
ENST00000652176.1
BICD cargo adaptor 1
chr4_-_83455796 0.03 ENST00000295488.8
ENST00000510985.1
helicase, POLQ like
chr4_+_83455962 0.03 ENST00000507019.5
mitochondrial ribosomal protein S18C
chrX_+_12137409 0.03 ENST00000672010.1
FERM and PDZ domain containing 4
chr17_-_48614628 0.03 ENST00000576562.1
homeobox B8
chr1_-_151831768 0.03 ENST00000318247.7
RAR related orphan receptor C
chr12_+_110502200 0.03 ENST00000409246.5
ENST00000392672.8
ENST00000409425.5
RAD9 checkpoint clamp component B
chr11_+_63681444 0.03 ENST00000341307.6
ENST00000356000.7
ENST00000542238.5
reticulon 3
chr1_+_202122881 0.03 ENST00000683302.1
ENST00000683557.1
G protein-coupled receptor 37 like 1
chrX_+_155071473 0.03 ENST00000369459.6
ENST00000369462.5
ENST00000330045.12
ENST00000411985.5
ENST00000399042.4
ENST00000620502.4
ENST00000630295.1
BRCA1/BRCA2-containing complex subunit 3
chrX_-_129523436 0.03 ENST00000371123.5
ENST00000371121.5
ENST00000371122.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr16_+_30064142 0.03 ENST00000562168.5
ENST00000569545.5
aldolase, fructose-bisphosphate A
chr12_+_78036248 0.03 ENST00000644176.1
neuron navigator 3
chr2_-_100142575 0.03 ENST00000317233.8
ENST00000672204.1
ENST00000416492.5
ENST00000672857.1
ENST00000672756.2
AF4/FMR2 family member 3
chr12_+_104286881 0.03 ENST00000526691.5
ENST00000531691.5
ENST00000526390.5
ENST00000531689.5
thioredoxin reductase 1
chr12_+_110502307 0.03 ENST00000409778.7
ENST00000409300.6
RAD9 checkpoint clamp component B
chr1_-_11803383 0.03 ENST00000641407.1
ENST00000376583.7
ENST00000423400.7
methylenetetrahydrofolate reductase
chr2_-_208255055 0.03 ENST00000345146.7
isocitrate dehydrogenase (NADP(+)) 1
chrX_+_123184153 0.03 ENST00000616590.4
glutamate ionotropic receptor AMPA type subunit 3
chr8_-_42207557 0.02 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
plasminogen activator, tissue type
chr19_+_15049469 0.02 ENST00000427043.4
caspase 14

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0060931 sinoatrial node cell development(GO:0060931) His-Purkinje system cell differentiation(GO:0060932)
0.1 0.4 GO:0021816 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 1.6 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.4 GO:0048294 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.2 GO:0015847 putrescine transport(GO:0015847)
0.1 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.3 GO:0046439 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) homocysteine catabolic process(GO:0043418) L-cysteine metabolic process(GO:0046439)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 1.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.4 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.6 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.7 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0060366 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.6 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.2 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:0021859 pyramidal neuron differentiation(GO:0021859)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.1 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.0 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.5 GO:0044305 calyx of Held(GO:0044305)
0.1 0.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.0 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.3 GO:0098809 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.2 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0022841 outward rectifier potassium channel activity(GO:0015271) potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.0 GO:0036505 prosaposin receptor activity(GO:0036505)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling