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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for BACH1_NFE2_NFE2L2

Z-value: 0.27

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Transcription factors associated with BACH1_NFE2_NFE2L2

Gene Symbol Gene ID Gene Info
BACH1
ENSG00000156273.16 BTB domain and CNC homolog 1
NFE2
ENSG00000123405.14 nuclear factor, erythroid 2
NFE2L2
ENSG00000116044.16 nuclear factor, erythroid 2 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BACH1hg38_v1_chr21_+_29299368_29299441,
hg38_v1_chr21_+_29298890_29298932		0.611.1e-01Click!
NFE2L2hg38_v1_chr2_-_177263522_177263572,
hg38_v1_chr2_-_177263800_177263870		-0.403.3e-01Click!

Activity profile of BACH1_NFE2_NFE2L2 motif

Sorted Z-values of BACH1_NFE2_NFE2L2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_55681647 0.68 ENST00000614691.1
METTL7B
methyltransferase like 7B
chr12_+_55681711 0.67 ENST00000394252.4
METTL7B
methyltransferase like 7B
chr10_-_125816510 0.62 ENST00000650587.1
UROS
uroporphyrinogen III synthase
chr10_-_125816596 0.58 ENST00000368786.5
UROS
uroporphyrinogen III synthase
chr8_-_30727777 0.47 ENST00000537535.5
ENST00000541648.5
ENST00000546342.5
ENST00000221130.11
GSR
glutathione-disulfide reductase
chr11_-_2903490 0.45 ENST00000455942.3
ENST00000625099.4
SLC22A18AS
solute carrier family 22 member 18 antisense
chr5_-_150155828 0.40 ENST00000261799.9
PDGFRB
platelet derived growth factor receptor beta
chr10_-_75109085 0.40 ENST00000607131.5
DUSP13
dual specificity phosphatase 13
chr14_+_21990357 0.38 ENST00000390444.1
TRAV16
T cell receptor alpha variable 16
chr5_+_179820895 0.38 ENST00000504627.1
ENST00000389805.9
ENST00000510187.5
SQSTM1
sequestosome 1
chr12_+_10213417 0.37 ENST00000546017.5
ENST00000535576.5
ENST00000539170.5
GABARAPL1
GABA type A receptor associated protein like 1
chr10_-_75109172 0.36 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
DUSP13
dual specificity phosphatase 13
chr2_+_54115437 0.35 ENST00000303536.8
ENST00000394666.7
ACYP2
acylphosphatase 2
chr19_-_58511981 0.30 ENST00000263093.7
ENST00000601355.1
SLC27A5
solute carrier family 27 member 5
chr16_-_69726506 0.29 ENST00000561500.5
ENST00000320623.10
ENST00000439109.6
ENST00000564043.1
ENST00000379046.6
ENST00000379047.7
NQO1
NAD(P)H quinone dehydrogenase 1
chr7_+_134527560 0.29 ENST00000359579.5
AKR1B10
aldo-keto reductase family 1 member B10
chr2_+_54115396 0.28 ENST00000406041.5
ACYP2
acylphosphatase 2
chrX_-_15493234 0.28 ENST00000380420.10
PIR
pirin
chr7_+_22727147 0.28 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
IL6
interleukin 6
chr4_-_993376 0.27 ENST00000398520.6
ENST00000398516.3
SLC26A1
solute carrier family 26 member 1
chr19_+_18386150 0.26 ENST00000252809.3
GDF15
growth differentiation factor 15
chr1_-_45521931 0.25 ENST00000447184.6
ENST00000262746.5
PRDX1
peroxiredoxin 1
chr1_-_45521854 0.25 ENST00000372079.1
ENST00000319248.13
PRDX1
peroxiredoxin 1
chr6_-_35921079 0.25 ENST00000507909.1
ENST00000373825.7
SRPK1
SRSF protein kinase 1
chr6_-_35921128 0.24 ENST00000510290.5
ENST00000423325.6
SRPK1
SRSF protein kinase 1
chr14_-_64942720 0.23 ENST00000557049.1
ENST00000389614.6
GPX2
glutathione peroxidase 2
chr16_+_2033264 0.23 ENST00000565855.5
ENST00000566198.1
SLC9A3R2
SLC9A3 regulator 2
chr19_+_18588789 0.23 ENST00000450195.6
ENST00000358607.11
REX1BD
required for excision 1-B domain containing
chr17_-_75154534 0.22 ENST00000356033.8
JPT1
Jupiter microtubule associated homolog 1
chr16_+_30065753 0.22 ENST00000642816.3
ENST00000643777.4
ENST00000569798.5
ALDOA
aldolase, fructose-bisphosphate A
chr2_-_210315160 0.21 ENST00000352451.4
MYL1
myosin light chain 1
chr17_+_18183052 0.20 ENST00000541285.1
ALKBH5
alkB homolog 5, RNA demethylase
chr21_+_31659666 0.20 ENST00000389995.4
ENST00000270142.11
SOD1
superoxide dismutase 1
chr14_-_64942783 0.20 ENST00000612794.1
GPX2
glutathione peroxidase 2
chr1_-_243843226 0.20 ENST00000336199.9
AKT3
AKT serine/threonine kinase 3
chr4_-_993430 0.20 ENST00000361661.6
ENST00000622731.4
SLC26A1
solute carrier family 26 member 1
chr17_-_35063648 0.20 ENST00000394597.7
RFFL
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
chr11_-_111923722 0.20 ENST00000527950.5
CRYAB
crystallin alpha B
chr10_-_91633057 0.19 ENST00000238994.6
PPP1R3C
protein phosphatase 1 regulatory subunit 3C
chr19_+_46303599 0.19 ENST00000300862.7
HIF3A
hypoxia inducible factor 3 subunit alpha
chr16_+_30065777 0.18 ENST00000395240.7
ENST00000566846.5
ALDOA
aldolase, fructose-bisphosphate A
chr5_-_177496802 0.18 ENST00000506161.5
PDLIM7
PDZ and LIM domain 7
chr10_-_5977492 0.18 ENST00000530685.5
ENST00000397255.7
ENST00000379971.5
ENST00000528354.5
ENST00000397250.6
ENST00000429135.2
IL15RA
interleukin 15 receptor subunit alpha
chr8_-_100336184 0.18 ENST00000519527.5
ENST00000522369.5
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr17_+_81977587 0.17 ENST00000306739.9
ENST00000581647.5
ENST00000580534.5
ENST00000579684.5
ASPSCR1
ASPSCR1 tether for SLC2A4, UBX domain containing
chr5_-_177496845 0.17 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7
chr17_-_30291930 0.17 ENST00000261714.11
BLMH
bleomycin hydrolase
chr12_+_12357056 0.16 ENST00000314565.9
ENST00000542728.5
BORCS5
BLOC-1 related complex subunit 5
chr6_-_35921047 0.16 ENST00000361690.7
ENST00000512445.5
SRPK1
SRSF protein kinase 1
chr6_-_132659178 0.16 ENST00000275216.3
TAAR1
trace amine associated receptor 1
chr5_-_142685654 0.16 ENST00000378046.5
ENST00000619447.4
FGF1
fibroblast growth factor 1
chr11_-_47185840 0.16 ENST00000539589.5
ENST00000528462.5
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr11_-_102955705 0.16 ENST00000615555.4
ENST00000340273.4
ENST00000260302.8
MMP13
matrix metallopeptidase 13
chr22_+_18906303 0.16 ENST00000331444.12
ENST00000608842.1
DGCR6
DiGeorge syndrome critical region gene 6
chr20_-_653189 0.15 ENST00000381962.4
SRXN1
sulfiredoxin 1
chr16_+_89921851 0.15 ENST00000554444.5
ENST00000556565.5
TUBB3
tubulin beta 3 class III
chr11_-_707063 0.15 ENST00000683307.1
DEAF1
DEAF1 transcription factor
chr6_-_28354193 0.15 ENST00000396838.6
ENST00000426434.1
ENST00000434036.5
ENST00000439628.5
ZSCAN31
zinc finger and SCAN domain containing 31
chr8_-_132111159 0.15 ENST00000673615.1
ENST00000434736.6
HHLA1
HERV-H LTR-associating 1
chrX_+_154542194 0.15 ENST00000618670.4
IKBKG
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr14_+_58244821 0.14 ENST00000216455.9
ENST00000412908.6
ENST00000557508.5
PSMA3
proteasome 20S subunit alpha 3
chr11_-_9003994 0.14 ENST00000309166.8
ENST00000525100.1
ENST00000531090.5
NRIP3
nuclear receptor interacting protein 3
chr10_+_35195843 0.14 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr5_+_55102635 0.14 ENST00000274306.7
GZMA
granzyme A
chrX_+_12975083 0.14 ENST00000451311.7
ENST00000380636.1
TMSB4X
thymosin beta 4 X-linked
chr9_+_100429511 0.14 ENST00000613183.1
MSANTD3
Myb/SANT DNA binding domain containing 3
chr3_-_48016400 0.14 ENST00000434267.5
ENST00000683076.1
ENST00000633710.1
MAP4
microtubule associated protein 4
chr10_+_84139491 0.13 ENST00000372134.6
GHITM
growth hormone inducible transmembrane protein
chr18_+_11857440 0.13 ENST00000602628.1
GNAL
G protein subunit alpha L
chr9_-_137028223 0.13 ENST00000341511.11
ABCA2
ATP binding cassette subfamily A member 2
chr19_-_45782388 0.13 ENST00000458663.6
DMPK
DM1 protein kinase
chr3_+_69866217 0.13 ENST00000314589.10
MITF
melanocyte inducing transcription factor
chr8_+_106447918 0.13 ENST00000442977.6
OXR1
oxidation resistance 1
chr3_-_150022799 0.13 ENST00000649949.1
ENST00000494827.5
PFN2
profilin 2
chr9_+_137188646 0.12 ENST00000322310.10
SSNA1
SS nuclear autoantigen 1
chr8_-_26867267 0.12 ENST00000380573.4
ADRA1A
adrenoceptor alpha 1A
chr3_-_149576203 0.12 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr9_+_137188697 0.12 ENST00000464553.2
SSNA1
SS nuclear autoantigen 1
chr17_-_78925376 0.12 ENST00000262768.11
TIMP2
TIMP metallopeptidase inhibitor 2
chrX_+_22136552 0.12 ENST00000682888.1
ENST00000684356.1
PHEX
phosphate regulating endopeptidase homolog X-linked
chr1_+_52142044 0.12 ENST00000287727.8
ENST00000371591.2
ZFYVE9
zinc finger FYVE-type containing 9
chr9_-_137028271 0.12 ENST00000265662.9
ENST00000371605.7
ABCA2
ATP binding cassette subfamily A member 2
chr1_+_156786875 0.12 ENST00000526188.5
ENST00000454659.1
PRCC
proline rich mitotic checkpoint control factor
chr9_+_72577788 0.12 ENST00000645208.2
TMC1
transmembrane channel like 1
chr1_-_51331315 0.12 ENST00000262676.9
TTC39A
tetratricopeptide repeat domain 39A
chr3_+_51943244 0.12 ENST00000498510.2
PARP3
poly(ADP-ribose) polymerase family member 3
chr17_-_39730496 0.11 ENST00000577810.1
MIEN1
migration and invasion enhancer 1
chr10_-_70132801 0.11 ENST00000307864.3
ENST00000613322.4
AIFM2
apoptosis inducing factor mitochondria associated 2
chr9_-_70414657 0.11 ENST00000377126.4
KLF9
Kruppel like factor 9
chr17_-_39730524 0.11 ENST00000394231.8
MIEN1
migration and invasion enhancer 1
chr17_+_45221993 0.11 ENST00000328118.7
FMNL1
formin like 1
chr3_+_46163465 0.11 ENST00000357422.2
CCR3
C-C motif chemokine receptor 3
chr17_-_15566276 0.11 ENST00000630868.1
CDRT1
CMT1A duplicated region transcript 1
chr2_+_234050732 0.11 ENST00000425558.1
SPP2
secreted phosphoprotein 2
chr2_-_96505345 0.11 ENST00000310865.7
ENST00000451794.6
NEURL3
neuralized E3 ubiquitin protein ligase 3
chr9_+_2158487 0.11 ENST00000634706.1
ENST00000634338.1
ENST00000635688.1
ENST00000634435.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_-_23034878 0.10 ENST00000493471.2
ENST00000460922.2
ENST00000361611.11
PSMB5
proteasome 20S subunit beta 5
chr6_+_63521738 0.10 ENST00000648894.1
ENST00000639568.2
PTP4A1
protein tyrosine phosphatase 4A1
chr19_-_45639104 0.10 ENST00000586770.5
ENST00000591721.5
ENST00000245925.8
ENST00000590043.5
ENST00000589876.5
EML2
EMAP like 2
chr12_-_120250145 0.10 ENST00000458477.6
PXN
paxillin
chrX_+_150363258 0.10 ENST00000683696.1
MAMLD1
mastermind like domain containing 1
chrX_+_150363306 0.10 ENST00000370401.7
ENST00000432680.7
MAMLD1
mastermind like domain containing 1
chr10_-_25062279 0.10 ENST00000615958.4
ENKUR
enkurin, TRPC channel interacting protein
chr9_+_72577369 0.10 ENST00000651183.1
TMC1
transmembrane channel like 1
chr11_+_119087979 0.10 ENST00000535253.5
ENST00000392841.1
ENST00000648374.1
HMBS
hydroxymethylbilane synthase
chr1_-_243843164 0.10 ENST00000491219.6
ENST00000680056.1
ENST00000492957.2
AKT3
AKT serine/threonine kinase 3
chr14_-_75069478 0.09 ENST00000555463.1
ACYP1
acylphosphatase 1
chr22_+_22697789 0.09 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr17_+_77376083 0.09 ENST00000427674.6
SEPTIN9
septin 9
chr2_-_42764116 0.09 ENST00000378661.3
OXER1
oxoeicosanoid receptor 1
chr2_-_191020960 0.09 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1
chr17_+_18183803 0.09 ENST00000399138.5
ALKBH5
alkB homolog 5, RNA demethylase
chr22_+_44676808 0.09 ENST00000624862.3
PRR5
proline rich 5
chr4_+_17614630 0.09 ENST00000237380.12
MED28
mediator complex subunit 28
chr15_-_82647960 0.09 ENST00000615198.4
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr9_-_127874964 0.08 ENST00000373156.5
AK1
adenylate kinase 1
chr16_-_1379674 0.08 ENST00000402641.6
ENST00000248104.11
ENST00000674376.1
ENST00000397464.5
UNKL
unk like zinc finger
chr17_+_21288029 0.08 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
MAP2K3
mitogen-activated protein kinase kinase 3
chr21_+_32298849 0.08 ENST00000303645.10
MRAP
melanocortin 2 receptor accessory protein
chr3_-_71725365 0.08 ENST00000425534.8
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr6_+_56955097 0.08 ENST00000370746.8
ENST00000370748.7
BEND6
BEN domain containing 6
chr16_+_11965193 0.08 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chr5_+_150640652 0.08 ENST00000307662.5
SYNPO
synaptopodin
chr19_-_38899529 0.08 ENST00000249396.12
ENST00000437828.5
SIRT2
sirtuin 2
chr22_-_45212431 0.08 ENST00000496226.1
ENST00000251993.11
KIAA0930
KIAA0930
chr17_+_7440738 0.08 ENST00000575398.5
ENST00000575082.5
FGF11
fibroblast growth factor 11
chr10_+_68106109 0.08 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr10_+_132066003 0.08 ENST00000657318.1
ENST00000666210.1
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr10_-_70146602 0.08 ENST00000335494.5
ENST00000287078.7
TYSND1
trypsin like peroxisomal matrix peptidase 1
chr14_+_79279403 0.08 ENST00000281127.11
NRXN3
neurexin 3
chr3_+_126704202 0.08 ENST00000290913.8
ENST00000508789.5
CHCHD6
coiled-coil-helix-coiled-coil-helix domain containing 6
chr1_-_162868761 0.08 ENST00000367910.5
ENST00000367912.6
CCDC190
coiled-coil domain containing 190
chr14_+_34993240 0.08 ENST00000677647.1
SRP54
signal recognition particle 54
chr16_+_29808125 0.07 ENST00000568282.1
MAZ
MYC associated zinc finger protein
chr22_+_22704265 0.07 ENST00000390307.2
IGLV3-22
immunoglobulin lambda variable 3-22
chr4_-_165279679 0.07 ENST00000505354.2
GK3P
glycerol kinase 3 pseudogene
chr10_-_50279715 0.07 ENST00000395526.9
ASAH2
N-acylsphingosine amidohydrolase 2
chr16_+_8642375 0.07 ENST00000562973.1
METTL22
methyltransferase like 22
chr8_-_100105955 0.07 ENST00000523437.5
RGS22
regulator of G protein signaling 22
chr19_-_38899800 0.07 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
SIRT2
sirtuin 2
chr2_+_89851723 0.07 ENST00000429992.2
IGKV2D-40
immunoglobulin kappa variable 2D-40
chr20_+_17699942 0.07 ENST00000427254.1
ENST00000377805.7
BANF2
BANF family member 2
chr1_-_46132650 0.07 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
PIK3R3
phosphoinositide-3-kinase regulatory subunit 3
chr1_-_150235972 0.07 ENST00000534220.1
ANP32E
acidic nuclear phosphoprotein 32 family member E
chr12_+_104286881 0.07 ENST00000526691.5
ENST00000531691.5
ENST00000526390.5
ENST00000531689.5
TXNRD1
thioredoxin reductase 1
chr3_+_191329342 0.07 ENST00000392455.9
CCDC50
coiled-coil domain containing 50
chr1_-_235588959 0.07 ENST00000484517.2
GNG4
G protein subunit gamma 4
chr22_-_30667795 0.07 ENST00000404885.5
ENST00000403268.1
ENST00000407308.1
ENST00000334679.4
ENST00000342474.4
DUSP18
dual specificity phosphatase 18
chr6_-_53510445 0.07 ENST00000509541.5
GCLC
glutamate-cysteine ligase catalytic subunit
chr10_+_132065937 0.07 ENST00000658847.1
ENST00000666974.1
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr16_+_74296789 0.07 ENST00000219313.9
ENST00000567958.5
ENST00000568615.2
PSMD7
proteasome 26S subunit, non-ATPase 7
chr11_+_93741591 0.07 ENST00000528288.5
ENST00000617482.4
ENST00000540113.5
C11orf54
chromosome 11 open reading frame 54
chr4_+_15002443 0.06 ENST00000538197.7
CPEB2
cytoplasmic polyadenylation element binding protein 2
chr2_-_219308963 0.06 ENST00000423636.6
ENST00000442029.5
ENST00000412847.5
PTPRN
protein tyrosine phosphatase receptor type N
chr1_-_15809348 0.06 ENST00000483273.2
UQCRHL
ubiquinol-cytochrome c reductase hinge protein like
chr2_-_169031317 0.06 ENST00000650372.1
ABCB11
ATP binding cassette subfamily B member 11
chr3_+_184186023 0.06 ENST00000429586.6
ENST00000292808.5
ABCF3
ATP binding cassette subfamily F member 3
chr9_+_2158239 0.06 ENST00000635133.1
ENST00000634931.1
ENST00000423555.6
ENST00000382185.6
ENST00000302401.8
ENST00000382183.6
ENST00000417599.6
ENST00000382186.6
ENST00000635530.1
ENST00000635388.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrX_-_24647091 0.06 ENST00000356768.8
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr6_+_86937500 0.06 ENST00000305344.7
HTR1E
5-hydroxytryptamine receptor 1E
chr11_+_10456186 0.06 ENST00000528723.5
AMPD3
adenosine monophosphate deaminase 3
chr5_+_150640678 0.06 ENST00000519664.1
SYNPO
synaptopodin
chr9_-_114078293 0.06 ENST00000265132.8
AMBP
alpha-1-microglobulin/bikunin precursor
chr11_+_20363780 0.06 ENST00000532505.1
HTATIP2
HIV-1 Tat interactive protein 2
chr2_+_90172802 0.06 ENST00000390277.3
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr16_+_87392327 0.06 ENST00000565788.1
ENST00000268607.10
MAP1LC3B
microtubule associated protein 1 light chain 3 beta
chr19_+_38374758 0.06 ENST00000585598.1
ENST00000602911.5
ENST00000592561.5
PSMD8
proteasome 26S subunit, non-ATPase 8
chr10_-_72217126 0.06 ENST00000317126.8
ASCC1
activating signal cointegrator 1 complex subunit 1
chr2_-_89027700 0.06 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr20_-_1329131 0.06 ENST00000360779.4
SDCBP2
syndecan binding protein 2
chr17_+_4950147 0.06 ENST00000522301.5
ENO3
enolase 3
chr3_-_170870033 0.06 ENST00000466674.5
ENST00000295830.13
ENST00000463836.1
RPL22L1
ribosomal protein L22 like 1
chr19_+_38374557 0.06 ENST00000215071.9
PSMD8
proteasome 26S subunit, non-ATPase 8
chr9_+_2157647 0.06 ENST00000452193.5
ENST00000324954.10
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_-_110256466 0.06 ENST00000374515.9
ENST00000374517.6
TXN
thioredoxin
chr1_-_17045219 0.06 ENST00000491274.5
SDHB
succinate dehydrogenase complex iron sulfur subunit B
chr5_+_161848112 0.06 ENST00000393943.10
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr4_-_86453278 0.06 ENST00000638867.2
ENST00000642019.1
ENST00000641313.1
MAPK10
mitogen-activated protein kinase 10
chr7_-_100428657 0.06 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
ZCWPW1
zinc finger CW-type and PWWP domain containing 1
chr1_-_150235943 0.05 ENST00000533654.5
ANP32E
acidic nuclear phosphoprotein 32 family member E
chrX_+_136487940 0.05 ENST00000370648.4
BRS3
bombesin receptor subtype 3
chr22_+_44677077 0.05 ENST00000403581.5
PRR5
proline rich 5
chr19_+_38374549 0.05 ENST00000620216.4
PSMD8
proteasome 26S subunit, non-ATPase 8
chr12_+_8157034 0.05 ENST00000396570.7
ZNF705A
zinc finger protein 705A
chr16_+_31117656 0.05 ENST00000219797.9
ENST00000448516.6
KAT8
lysine acetyltransferase 8
chr6_+_44247087 0.05 ENST00000353801.7
ENST00000371646.10
HSP90AB1
heat shock protein 90 alpha family class B member 1
chr18_-_57586668 0.05 ENST00000592699.6
ENST00000382873.8
ENST00000262093.11
ENST00000652755.1
FECH
ferrochelatase
chr1_+_44775531 0.05 ENST00000396651.8
ENST00000372209.3
RPS8
ribosomal protein S8
chr13_+_108269629 0.05 ENST00000430559.5
ENST00000375887.9
TNFSF13B
TNF superfamily member 13b
chr19_+_38899680 0.05 ENST00000576510.5
ENST00000392079.7
NFKBIB
NFKB inhibitor beta
chr10_-_97292625 0.05 ENST00000466484.1
ENST00000358531.9
ENST00000358308.7
ARHGAP19
Rho GTPase activating protein 19
chr17_-_7219813 0.05 ENST00000399510.8
ENST00000648172.8
DLG4
discs large MAGUK scaffold protein 4
chr11_+_67583803 0.05 ENST00000398606.10
GSTP1
glutathione S-transferase pi 1
chr20_-_44210697 0.05 ENST00000255174.3
OSER1
oxidative stress responsive serine rich 1
chr10_+_104254163 0.05 ENST00000539281.5
GSTO1
glutathione S-transferase omega 1
chr6_-_83431038 0.05 ENST00000369705.4
ME1
malic enzyme 1
chr22_+_22395005 0.05 ENST00000390298.2
IGLV7-43
immunoglobulin lambda variable 7-43
chr19_+_16185380 0.05 ENST00000589852.5
ENST00000263384.12
ENST00000588367.5
ENST00000587351.1
FAM32A
family with sequence similarity 32 member A
chrX_+_30653478 0.05 ENST00000378945.7
ENST00000378941.4
GK
glycerol kinase
chrX_-_71106728 0.05 ENST00000374251.6
CXorf65
chromosome X open reading frame 65

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH1_NFE2_NFE2L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.4 GO:0072276 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1 0.3 GO:0016487 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.1 0.3 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.3 GO:1990637 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.1 0.2 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
0.0 0.5 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.1 GO:0035732 nitric oxide storage(GO:0035732)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.8 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.0 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.0 0.2 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.0 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.2 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 1.0 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044753 amphisome(GO:0044753)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:1990913 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.7 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.1 0.3 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.1 GO:0035730 S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.9 PID TNF PATHWAY TNF receptor signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis