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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for BATF3

Z-value: 0.47

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Transcription factors associated with BATF3

Gene Symbol Gene ID Gene Info
BATF3
ENSG00000123685.9 basic leucine zipper ATF-like transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BATF3hg38_v1_chr1_-_212699817_212699846-0.763.0e-02Click!

Activity profile of BATF3 motif

Sorted Z-values of BATF3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_51002527 0.31 ENST00000595238.1
ENST00000600767.5
KLK8
kallikrein related peptidase 8
chr1_+_156061142 0.29 ENST00000361084.10
RAB25
RAB25, member RAS oncogene family
chr14_+_67619911 0.18 ENST00000261783.4
ARG2
arginase 2
chr5_-_176537361 0.17 ENST00000274811.9
RNF44
ring finger protein 44
chr12_-_122896066 0.16 ENST00000267202.7
ENST00000535765.5
VPS37B
VPS37B subunit of ESCRT-I
chr17_+_36103819 0.16 ENST00000615863.2
ENST00000621626.1
CCL4
C-C motif chemokine ligand 4
chr2_+_69915100 0.16 ENST00000264444.7
MXD1
MAX dimerization protein 1
chr2_+_69915041 0.16 ENST00000540449.5
MXD1
MAX dimerization protein 1
chr2_-_74529670 0.13 ENST00000377526.4
AUP1
AUP1 lipid droplet regulating VLDL assembly factor
chr10_+_97737115 0.12 ENST00000337540.11
ENST00000370613.7
ENST00000370610.7
ENST00000357540.8
ENST00000393677.8
ENST00000423811.3
ENST00000684270.1
ENST00000359980.5
ZFYVE27
zinc finger FYVE-type containing 27
chr12_+_7130341 0.11 ENST00000266546.11
CLSTN3
calsyntenin 3
chr1_+_153778178 0.10 ENST00000532853.5
SLC27A3
solute carrier family 27 member 3
chr6_-_90296824 0.10 ENST00000257749.9
BACH2
BTB domain and CNC homolog 2
chr15_+_34102037 0.10 ENST00000397766.4
PGBD4
piggyBac transposable element derived 4
chr6_-_90296908 0.09 ENST00000537989.5
BACH2
BTB domain and CNC homolog 2
chr14_-_24263162 0.09 ENST00000206765.11
ENST00000544573.5
TGM1
transglutaminase 1
chr22_+_31122923 0.09 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
INPP5J
inositol polyphosphate-5-phosphatase J
chr16_+_56191476 0.08 ENST00000262493.12
GNAO1
G protein subunit alpha o1
chr10_+_131900999 0.08 ENST00000455566.6
PPP2R2D
protein phosphatase 2 regulatory subunit Bdelta
chr10_+_122163426 0.07 ENST00000360561.7
TACC2
transforming acidic coiled-coil containing protein 2
chrX_-_135973975 0.07 ENST00000305963.3
ENST00000680510.1
ENST00000679621.1
MMGT1
membrane magnesium transporter 1
chr10_+_122163590 0.07 ENST00000368999.5
TACC2
transforming acidic coiled-coil containing protein 2
chr10_+_122163672 0.06 ENST00000369004.7
ENST00000260733.7
TACC2
transforming acidic coiled-coil containing protein 2
chr8_+_37736667 0.06 ENST00000518586.5
ENST00000335171.10
ENST00000521644.5
ERLIN2
ER lipid raft associated 2
chr6_+_139135063 0.06 ENST00000367658.3
HECA
hdc homolog, cell cycle regulator
chr11_+_66291887 0.05 ENST00000327259.5
TMEM151A
transmembrane protein 151A
chr1_+_92168915 0.05 ENST00000637221.2
BTBD8
BTB domain containing 8
chr22_+_38201932 0.05 ENST00000538999.1
ENST00000538320.5
ENST00000338483.7
ENST00000441709.1
MAFF
MAF bZIP transcription factor F
chr16_+_56191728 0.05 ENST00000638705.1
ENST00000262494.12
GNAO1
G protein subunit alpha o1
chr3_-_119463606 0.05 ENST00000319172.10
ENST00000491685.5
ENST00000461654.1
TMEM39A
transmembrane protein 39A
chr2_+_74530018 0.04 ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr15_-_34101807 0.04 ENST00000527822.5
ENST00000528949.1
ENST00000256545.9
EMC7
ER membrane protein complex subunit 7
chr16_+_68023276 0.04 ENST00000567100.5
ENST00000565263.6
ENST00000432752.5
ENST00000569289.5
ENST00000564781.1
DUS2
dihydrouridine synthase 2
chr3_+_38165484 0.04 ENST00000446845.5
ENST00000311806.8
OXSR1
oxidative stress responsive kinase 1
chr16_+_68023249 0.04 ENST00000358896.10
ENST00000568099.6
DUS2
dihydrouridine synthase 2
chrX_+_83861126 0.04 ENST00000621735.4
ENST00000329312.5
CYLC1
cylicin 1
chr19_-_47113756 0.04 ENST00000253048.10
ZC3H4
zinc finger CCCH-type containing 4
chr2_+_74529923 0.04 ENST00000258080.8
ENST00000352222.7
HTRA2
HtrA serine peptidase 2
chr11_-_85665077 0.03 ENST00000527447.2
CREBZF
CREB/ATF bZIP transcription factor
chr4_-_103198371 0.03 ENST00000611174.4
ENST00000380026.8
CENPE
centromere protein E
chr4_-_2009164 0.03 ENST00000542778.5
NELFA
negative elongation factor complex member A
chr8_+_37736612 0.03 ENST00000518526.5
ENST00000523887.5
ENST00000648919.1
ENST00000519638.3
ERLIN2
ER lipid raft associated 2
chr2_+_10043524 0.02 ENST00000305883.6
KLF11
Kruppel like factor 11
chr9_-_97922487 0.02 ENST00000455506.1
ENST00000375117.8
ENST00000375119.8
ENST00000611338.4
TRMO
tRNA methyltransferase O
chr18_+_79069385 0.02 ENST00000426216.6
ENST00000307671.12
ENST00000586672.5
ENST00000586722.5
ATP9B
ATPase phospholipid transporting 9B (putative)
chr2_+_10044175 0.02 ENST00000440320.5
ENST00000535335.1
KLF11
Kruppel like factor 11
chr16_-_68023201 0.02 ENST00000332395.7
DDX28
DEAD-box helicase 28
chr4_-_103198331 0.02 ENST00000265148.9
ENST00000514974.1
CENPE
centromere protein E
chr13_-_36297749 0.02 ENST00000491049.6
ENST00000503173.5
ENST00000239860.10
ENST00000379862.6
ENST00000239859.8
ENST00000379864.6
ENST00000510088.5
CCDC169
coiled-coil domain containing 169
chr11_+_102347205 0.02 ENST00000532832.5
ENST00000530675.5
ENST00000227758.7
ENST00000533742.5
ENST00000532672.5
ENST00000531259.5
ENST00000527465.1
BIRC2
baculoviral IAP repeat containing 2
chr2_-_201780878 0.02 ENST00000681152.1
ENST00000681312.1
ENST00000409632.7
ENST00000264276.11
ENST00000410052.1
ENST00000681303.1
ENST00000680287.1
ENST00000467448.5
ALS2
alsin Rho guanine nucleotide exchange factor ALS2
chr19_+_18612848 0.02 ENST00000262817.8
TMEM59L
transmembrane protein 59 like
chr4_-_2008835 0.02 ENST00000411649.3
ENST00000382882.9
ENST00000431323.6
NELFA
negative elongation factor complex member A
chr11_+_102347312 0.02 ENST00000621637.1
ENST00000613397.4
BIRC2
baculoviral IAP repeat containing 2
chr6_+_32972187 0.02 ENST00000607833.5
BRD2
bromodomain containing 2
chrX_+_48539665 0.01 ENST00000376771.9
ENST00000418627.1
TBC1D25
TBC1 domain family member 25
chr10_-_126521439 0.01 ENST00000284694.11
ENST00000432642.5
C10orf90
chromosome 10 open reading frame 90
chr8_-_66178455 0.01 ENST00000276571.5
CRH
corticotropin releasing hormone
chr4_-_39366342 0.01 ENST00000503784.1
ENST00000349703.7
ENST00000381897.5
RFC1
replication factor C subunit 1
chr17_-_51046868 0.01 ENST00000510283.5
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr17_+_31094969 0.01 ENST00000431387.8
ENST00000358273.9
NF1
neurofibromin 1
chr12_+_10212867 0.01 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABARAPL1
GABA type A receptor associated protein like 1
chr3_+_184338826 0.01 ENST00000453072.5
FAM131A
family with sequence similarity 131 member A
chr2_-_201781112 0.00 ENST00000681808.1
ENST00000681619.1
ENST00000680759.1
ENST00000680814.1
ENST00000680000.1
ENST00000679949.1
ENST00000679728.1
ALS2
alsin Rho guanine nucleotide exchange factor ALS2

Network of associatons between targets according to the STRING database.

First level regulatory network of BATF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.3 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.0 0.3 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.0 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.0 GO:0033150 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins