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avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)

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Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 1.80

Motif logo

Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol Gene ID Gene Info
ENSG00000180828.3 basic helix-loop-helix family member e22
ENSG00000180535.4 basic helix-loop-helix family member a15
ENSG00000125533.6 basic helix-loop-helix family member e23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BHLHA15hg38_v1_chr7_+_98211431_98211474-0.911.5e-03Click!
BHLHE22hg38_v1_chr8_+_64580357_64580374-0.531.8e-01Click!
BHLHE23hg38_v1_chr20_-_63006961_630070350.167.1e-01Click!

Activity profile of BHLHE22_BHLHA15_BHLHE23 motif

Sorted Z-values of BHLHE22_BHLHA15_BHLHE23 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_111976925 3.62 ENST00000395634.7
neuronal regeneration related protein
chr2_-_187513641 2.38 ENST00000392365.5
ENST00000435414.5
tissue factor pathway inhibitor
chr10_-_77090722 1.90 ENST00000638531.1
potassium calcium-activated channel subfamily M alpha 1
chr9_+_18474100 1.53 ENST00000327883.11
ENST00000431052.6
ENST00000380570.8
ENST00000380548.9
ADAMTS like 1
chr1_+_170664121 1.19 ENST00000239461.11
paired related homeobox 1
chr12_-_91179472 1.08 ENST00000550099.5
ENST00000546391.5
decorin
chr12_-_91179355 1.04 ENST00000550563.5
ENST00000546370.5
decorin
chr3_-_114758940 0.98 ENST00000464560.5
zinc finger and BTB domain containing 20
chr3_-_114759115 0.93 ENST00000471418.5
zinc finger and BTB domain containing 20
chr1_+_170663917 0.92 ENST00000497230.2
paired related homeobox 1
chr4_+_159267737 0.83 ENST00000264431.8
Rap guanine nucleotide exchange factor 2
chr2_-_162243375 0.74 ENST00000188790.9
ENST00000443424.5
fibroblast activation protein alpha
chr2_-_144516154 0.68 ENST00000637304.1
zinc finger E-box binding homeobox 2
chr1_-_186375671 0.59 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr5_-_59430600 0.54 ENST00000636120.1
phosphodiesterase 4D
chrX_+_71578435 0.52 ENST00000373696.8
germ cell nuclear acidic peptidase
chr12_-_108320635 0.48 ENST00000412676.5
ENST00000550573.5
chemerin chemokine-like receptor 1
chr4_+_54229261 0.46 ENST00000508170.5
ENST00000512143.1
ENST00000257290.10
platelet derived growth factor receptor alpha
chr3_-_179266971 0.44 ENST00000349697.2
ENST00000497599.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr15_-_55408018 0.43 ENST00000569205.5
cell cycle progression 1
chr22_-_28306645 0.42 ENST00000612946.4
tetratricopeptide repeat domain 28
chr2_+_209580024 0.41 ENST00000392194.5
microtubule associated protein 2
chr5_+_141373878 0.39 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr2_+_209579598 0.38 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr5_-_138338325 0.37 ENST00000510119.1
ENST00000513970.5
cell division cycle 25C
chr6_+_69232406 0.37 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr4_-_158173042 0.36 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr16_-_4846196 0.33 ENST00000589389.5
glyoxylate reductase 1 homolog
chr4_-_158173004 0.32 ENST00000585682.6
golgi associated kinase 1B
chr6_+_72366730 0.31 ENST00000414192.2
regulating synaptic membrane exocytosis 1
chr1_+_60865259 0.30 ENST00000371191.5
nuclear factor I A
chr7_+_148590760 0.30 ENST00000307003.3
chromosome 7 open reading frame 33
chr3_-_18438767 0.29 ENST00000454909.6
SATB homeobox 1
chr15_-_63156774 0.28 ENST00000462430.5
ribosomal protein S27 like
chr19_+_18097763 0.27 ENST00000262811.10
microtubule associated serine/threonine kinase 3
chr2_-_181680490 0.26 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
ceramide kinase like
neuronal differentiation 1
chr16_+_21704963 0.25 ENST00000388957.3
otoancorin
chr1_+_103750406 0.23 ENST00000370079.3
amylase alpha 1C
chr5_+_136160986 0.22 ENST00000507637.1
SMAD family member 5
chr5_+_173889337 0.22 ENST00000520867.5
ENST00000334035.9
cytoplasmic polyadenylation element binding protein 4
chr11_-_26722051 0.21 ENST00000396005.8
solute carrier family 5 member 12
chr4_+_113292838 0.20 ENST00000672411.1
ENST00000673231.1
ankyrin 2
chr4_+_113292925 0.19 ENST00000673353.1
ENST00000505342.6
ENST00000672915.1
ENST00000509550.5
ankyrin 2
chr3_-_121660892 0.19 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr15_-_55408245 0.19 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
cell cycle progression 1
chr10_+_134465 0.18 ENST00000439456.5
ENST00000397962.8
ENST00000309776.8
ENST00000397959.7
zinc finger MYND-type containing 11
chr5_+_138338256 0.17 ENST00000513056.5
ENST00000239906.10
ENST00000511276.1
family with sequence similarity 53 member C
chr7_-_98252117 0.17 ENST00000420697.1
ENST00000415086.5
ENST00000447648.7
tectonin beta-propeller repeat containing 1
chr3_-_42875871 0.17 ENST00000316161.6
ENST00000437102.1
cytochrome P450 family 8 subfamily B member 1
chr8_-_23457677 0.17 ENST00000356206.10
ENST00000417069.6
ectonucleoside triphosphate diphosphohydrolase 4
chr9_+_2158487 0.16 ENST00000634706.1
ENST00000634338.1
ENST00000635688.1
ENST00000634435.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_18474165 0.16 ENST00000380566.8
ADAMTS like 1
chr12_-_91179517 0.15 ENST00000551354.1
decorin
chr6_-_111793871 0.15 ENST00000368667.6
FYN proto-oncogene, Src family tyrosine kinase
chr18_+_34710307 0.15 ENST00000679796.1
dystrobrevin alpha
chr5_+_141968886 0.14 ENST00000347642.7
ring finger protein 14
chr9_-_127873462 0.14 ENST00000223836.10
adenylate kinase 1
chr11_+_17295322 0.14 ENST00000458064.6
ENST00000622082.4
nucleobindin 2
chr8_-_23457618 0.13 ENST00000358689.9
ENST00000518718.1
ectonucleoside triphosphate diphosphohydrolase 4
chr11_+_65638085 0.12 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1
chr3_-_126357399 0.12 ENST00000296233.4
Kruppel like factor 15
chr3_+_62319037 0.12 ENST00000494481.5
chromosome 3 open reading frame 14
chr9_+_2158239 0.12 ENST00000635133.1
ENST00000634931.1
ENST00000423555.6
ENST00000382185.6
ENST00000302401.8
ENST00000382183.6
ENST00000417599.6
ENST00000382186.6
ENST00000635530.1
ENST00000635388.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_134510182 0.11 ENST00000521673.5
zinc finger and AT-hook domain containing
chr3_+_62318983 0.11 ENST00000232519.9
ENST00000462069.6
ENST00000465142.5
chromosome 3 open reading frame 14
chr10_-_30999469 0.11 ENST00000538351.6
zinc finger protein 438
chr12_+_57772587 0.11 ENST00000300209.13
EEF1A lysine methyltransferase 3
chr2_-_32265732 0.10 ENST00000360906.9
ENST00000342905.10
NLR family CARD domain containing 4
chr4_-_73223082 0.10 ENST00000509867.6
ankyrin repeat domain 17
chr10_-_102418748 0.10 ENST00000020673.6
pleckstrin and Sec7 domain containing
chr1_+_100345018 0.10 ENST00000635056.2
ENST00000647005.1
cell division cycle 14A
chr20_-_35529618 0.09 ENST00000246199.5
ENST00000424444.1
ENST00000374345.8
ENST00000444723.3
chromosome 20 open reading frame 173
chr5_-_172006567 0.09 ENST00000517395.6
ENST00000265094.9
ENST00000393802.6
F-box and WD repeat domain containing 11
chr1_+_248508073 0.08 ENST00000641804.1
olfactory receptor family 2 subfamily G member 6
chr9_+_107306459 0.08 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr12_+_57772648 0.08 ENST00000333012.5
EEF1A lysine methyltransferase 3
chr3_-_149377637 0.07 ENST00000305366.8
transmembrane 4 L six family member 1
chr2_-_182522703 0.07 ENST00000410103.1
phosphodiesterase 1A
chr16_+_31108294 0.07 ENST00000287507.7
ENST00000394950.7
ENST00000219794.11
ENST00000561755.1
branched chain keto acid dehydrogenase kinase
chr5_-_172006817 0.07 ENST00000296933.10
F-box and WD repeat domain containing 11
chr6_+_96562548 0.07 ENST00000541107.5
ENST00000326771.2
four and a half LIM domains 5
chr20_+_43565115 0.07 ENST00000423407.7
serum/glucocorticoid regulated kinase 2
chr1_+_50103903 0.06 ENST00000371827.5
ELAV like RNA binding protein 4
chr2_-_153478753 0.06 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr9_+_12775012 0.06 ENST00000319264.4
leucine rich adaptor protein 1 like
chr15_+_65550819 0.06 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chrX_-_70289888 0.06 ENST00000239666.9
ENST00000374454.1
PDZ domain containing 11
chr3_+_137998735 0.06 ENST00000343735.8
claudin 18
chr18_+_34710249 0.06 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
dystrobrevin alpha
chr14_+_76826372 0.05 ENST00000393774.7
ENST00000555189.1
leucine rich repeat containing 74A
chr11_-_89063631 0.05 ENST00000455756.6
glutamate metabotropic receptor 5
chr1_+_159302321 0.05 ENST00000368114.1
Fc fragment of IgE receptor Ia
chr2_+_108378176 0.05 ENST00000409309.3
sulfotransferase family 1C member 4
chr4_+_153257339 0.05 ENST00000676374.1
ENST00000676196.1
ENST00000674935.1
ENST00000674769.1
ENST00000674896.1
ENST00000676191.1
ENST00000675312.1
ENST00000675456.1
ENST00000674847.1
ENST00000675977.1
ENST00000676264.1
ENST00000674726.1
ENST00000676252.1
ENST00000674730.1
ENST00000675738.1
ENST00000482578.3
tripartite motif containing 2
chr17_-_181640 0.05 ENST00000613549.3
double C2 domain beta
chr7_+_107891135 0.05 ENST00000639772.1
ENST00000440410.5
ENST00000437604.6
ENST00000205402.10
dihydrolipoamide dehydrogenase
chr11_+_55883297 0.05 ENST00000449290.6
tripartite motif-containing 51
chr6_+_37433197 0.05 ENST00000455891.5
ENST00000373451.9
cap methyltransferase 1
chr1_-_205121986 0.04 ENST00000367164.1
RB binding protein 5, histone lysine methyltransferase complex subunit
chrX_+_108091752 0.04 ENST00000457035.5
ENST00000372232.8
autophagy related 4A cysteine peptidase
chr3_+_172040554 0.04 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr2_-_182522556 0.04 ENST00000435564.5
phosphodiesterase 1A
chrX_+_108091665 0.04 ENST00000345734.7
autophagy related 4A cysteine peptidase
chr19_+_57363469 0.04 ENST00000282282.4
ENST00000543226.2
ENST00000596755.1
ENST00000597658.1
zinc finger protein 547
trafficking protein particle complex 2B
novel protein
chr9_+_105662457 0.04 ENST00000334077.6
TAL bHLH transcription factor 2
chr13_+_111114550 0.04 ENST00000317133.9
Rho guanine nucleotide exchange factor 7
chr12_-_95003666 0.04 ENST00000327772.7
ENST00000547157.1
ENST00000684171.1
ENST00000547986.5
NADH:ubiquinone oxidoreductase subunit A12
chr14_-_50831046 0.04 ENST00000476352.5
ENST00000324330.13
ENST00000382041.7
ENST00000453401.6
ENST00000530997.7
ninein
chr5_-_115296610 0.04 ENST00000379611.10
ENST00000506442.5
coiled-coil domain containing 112
chr14_-_50830479 0.04 ENST00000382043.8
ninein
chr6_-_118710065 0.04 ENST00000392500.7
ENST00000368488.9
ENST00000434604.5
centrosomal protein 85 like
chr2_+_108377947 0.03 ENST00000272452.7
sulfotransferase family 1C member 4
chr1_+_12464912 0.03 ENST00000543766.2
vacuolar protein sorting 13 homolog D
chr7_-_99976017 0.03 ENST00000411734.1
ENST00000292401.9
alpha-2-glycoprotein 1, zinc-binding
chr2_+_97669739 0.03 ENST00000599501.6
ENST00000627399.3
ENST00000627284.2
ENST00000599435.5
ENST00000597654.5
ENST00000598737.5
chromosome 2 open reading frame 92
chr15_+_57219411 0.03 ENST00000543579.5
ENST00000537840.5
ENST00000343827.7
transcription factor 12
chr3_-_50350710 0.03 ENST00000232501.8
NPR2 like, GATOR1 complex subunit
chr11_+_120236635 0.03 ENST00000260264.8
POU class 2 homeobox 3
chr4_+_2812259 0.03 ENST00000502260.5
ENST00000435136.8
SH3 domain binding protein 2
chr12_+_64610458 0.03 ENST00000542104.6
Ras association domain family member 3
chr1_+_148748774 0.03 ENST00000322209.5
nudix hydrolase 4B
chr19_+_55857437 0.02 ENST00000587891.5
NLR family pyrin domain containing 4
chrX_+_70290077 0.02 ENST00000374403.4
kinesin family member 4A
chr8_+_67064316 0.02 ENST00000675306.2
ENST00000678017.1
ENST00000262210.11
ENST00000675869.1
ENST00000677009.1
ENST00000676847.1
ENST00000676471.1
ENST00000678542.1
ENST00000677619.1
ENST00000676605.1
ENST00000678553.1
ENST00000674993.1
ENST00000678318.1
ENST00000676573.1
ENST00000676317.1
ENST00000677592.1
ENST00000679226.1
ENST00000675955.1
ENST00000676882.1
ENST00000678616.1
ENST00000678645.1
ENST00000678747.1
centrosome and spindle pole associated protein 1
chr18_+_13277351 0.02 ENST00000679091.1
low density lipoprotein receptor class A domain containing 4
chr10_+_5094405 0.01 ENST00000380554.5
aldo-keto reductase family 1 member C3
chr10_+_18340699 0.01 ENST00000377329.10
calcium voltage-gated channel auxiliary subunit beta 2
chr10_-_67838019 0.01 ENST00000483798.6
DnaJ heat shock protein family (Hsp40) member C12
chr5_+_157180816 0.01 ENST00000422843.8
IL2 inducible T cell kinase
chr15_-_65211463 0.01 ENST00000261883.6
cartilage intermediate layer protein
chrX_-_19799751 0.00 ENST00000379698.8
SH3 domain containing kinase binding protein 1
chr12_-_52703522 0.00 ENST00000341809.8
keratin 77
chr3_-_132035004 0.00 ENST00000429747.6
copine 4
chr9_+_68356603 0.00 ENST00000396396.6
phosphoglucomutase 5
chr14_-_106025628 0.00 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr10_-_67838091 0.00 ENST00000339758.7
DnaJ heat shock protein family (Hsp40) member C12
chr7_-_48029102 0.00 ENST00000297325.9
ENST00000412142.5
ENST00000395572.6
Sad1 and UNC84 domain containing 3
chr7_+_116862552 0.00 ENST00000361183.8
ENST00000639546.1
ENST00000490693.5
capping actin protein of muscle Z-line subunit alpha 2
chr10_+_134703 0.00 ENST00000509513.6
zinc finger MYND-type containing 11
chr15_+_67067780 0.00 ENST00000679624.1
SMAD family member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.3 2.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.6 GO:0031453 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453)
0.2 0.7 GO:0097325 melanocyte proliferation(GO:0097325)
0.2 0.5 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 2.1 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.9 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 2.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.4 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.7 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.5 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 1.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.5 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854) positive regulation of macrophage differentiation(GO:0045651)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.7 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 1.9 GO:0005901 caveola(GO:0005901)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 0.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 2.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.8 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 2.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.5 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.4 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects