Project
avrg: Epithelial-Mesenchymal Transition, human (Scheel, 2011)
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Results for DMBX1
Z-value: 0.77
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Transcription factors associated with DMBX1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| DMBX1 | hg38_v1_chr1_+_46489800_46489842 | 0.04 | 9.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_70553638 Show fit | 0.76 |
ENST00000444975.5
ENST00000445399.5 ENST00000295400.11 ENST00000418333.6 |
transforming growth factor alpha |
|
| chr10_+_116427839 Show fit | 0.66 |
ENST00000369230.4
|
pancreatic lipase related protein 3 |
|
| chr18_+_31447732 Show fit | 0.63 |
ENST00000257189.5
|
desmoglein 3 |
|
| chr6_-_106975616 Show fit | 0.57 |
ENST00000610952.1
|
CD24 molecule |
|
| chr2_-_70553440 Show fit | 0.55 |
ENST00000450929.5
|
transforming growth factor alpha |
|
| chrX_-_103311004 Show fit | 0.53 |
ENST00000372674.5
|
brain expressed X-linked 2 |
|
| chr8_-_124565699 Show fit | 0.40 |
ENST00000519168.5
|
MTSS I-BAR domain containing 1 |
|
| chrX_-_32155462 Show fit | 0.33 |
ENST00000359836.5
ENST00000378707.7 ENST00000541735.5 ENST00000684130.1 ENST00000682238.1 ENST00000620040.5 ENST00000474231.5 |
dystrophin |
|
| chr7_+_148339452 Show fit | 0.26 |
ENST00000463592.3
|
contactin associated protein 2 |
|
| chr17_-_4739866 Show fit | 0.26 |
ENST00000574412.6
ENST00000293778.12 |
C-X-C motif chemokine ligand 16 |
Network of associatons between targets according to the STRING database.
First level regulatory network of DMBX1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.1 | 0.6 | GO:0032913 | B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606) |
| 0.1 | 0.4 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.1 | 0.3 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
| 0.0 | 0.3 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 0.3 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.0 | 0.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.0 | 0.1 | GO:1902960 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.0 | 0.1 | GO:0002331 | pre-B cell allelic exclusion(GO:0002331) |
| 0.0 | 0.1 | GO:1990167 | protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.0 | 0.6 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 0.6 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.3 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.0 | 0.3 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.0 | 0.1 | GO:1990246 | uniplex complex(GO:1990246) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.7 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.6 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.0 | 0.4 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.3 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.2 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.0 | 0.1 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 0.0 | 0.1 | GO:0042835 | BRE binding(GO:0042835) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |